Subcellular Location: cytosol
Found 500 associated metabolites.
5557 associated genes.
AAAS, AACS, AAGAB, AAK1, AAMP, AANAT, AARS1, AASDHPPT, AASS, ABCA12, ABCB4, ABCB6, ABCD1, ABCD2, ABCD3, ABCE1, ABCF1, ABHD10, ABHD14B, ABHD5, ABI1, ABI2, ABL1, ABL2, ABR, ABRAXAS2, ABTB1, ACAA1, ACACA, ACACB, ACAT2, ACBD5, ACBD6, ACIN1, ACKR2, ACLY, ACMSD, ACO1, ACO2, ACOT1, ACOT11, ACOT12, ACOT13, ACOT2, ACOT4, ACOT6, ACOT7, ACOT8, ACOX1, ACOX2, ACOX3, ACP1, ACP3, ACP5, ACSBG1, ACSBG2, ACSS2, ACTA1, ACTA2, ACTB, ACTC1, ACTG1, ACTG2, ACTN1, ACTN2, ACTN3, ACTR10, ACTR1A, ACTR1B, ACTR2, ACTR3, ACVR1B, ACY1, ACY3, ADA, ADAL, ADAM17, ADAM18, ADAP1, ADAR, ADARB1, ADCY10, ADCY9, ADD1, ADD2, ADD3, ADGRD1, ADGRG2, ADH1A, ADH1B, ADH1C, ADH4, ADH5, ADH6, ADH7, ADI1, ADIRF, ADK, ADO, ADPRM, ADRA1A, ADRA2B, ADRM1, ADSL, ADSS1, ADSS2, AFAP1, AFAP1L1, AFAP1L2, AFDN, AFF3, AFMID, AFTPH, AGAP2, AGBL1, AGBL2, AGBL3, AGBL4, AGBL5, AGFG1, AGK, AGL, AGO1, AGO2, AGO3, AGO4, AGPS, AGTPBP1, AGXT, AHCTF1, AHCY, AHCYL1, AHCYL2, AHI1, AHNAK, AHNAK2, AHR, AHRR, AHSA1, AHSA2P, AICDA, AIF1, AIFM1, AIFM2, AIFM3, AIM2, AIMP1, AIMP2, AIP, AIPL1, AIRIM, AJUBA, AK1, AK5, AK7, AK8, AK9, AKAIN1, AKAP1, AKAP10, AKAP11, AKAP12, AKAP13, AKAP17A, AKAP5, AKAP7, AKAP9, AKNA, AKR1A1, AKR1B1, AKR1B10, AKR1B15, AKR1C1, AKR1C2, AKR1C3, AKR1C4, AKR1D1, AKR1E2, AKR7A2, AKR7A3, AKR7L, AKT1, AKT1S1, AKT2, ALAD, ALAS1, ALB, ALDH1A1, ALDH1A2, ALDH1A3, ALDH1B1, ALDH1L1, ALDH3A1, ALDH3A2, ALDH3B1, ALDH4A1, ALDH7A1, ALDH8A1, ALDH9A1, ALDOA, ALDOB, ALDOC, ALG2, ALKBH3, ALKBH5, ALKBH8, ALMS1, ALOX12, ALOX12B, ALOX15, ALOX15B, ALOX5, ALOXE3, ALPK1, ALS2, ALS2CL, ALYREF, AMACR, AMBP, AMBRA1, AMD1, AMDHD1, AMDHD2, AMER1, AMFR, AMOT, AMOTL1, AMOTL2, AMPD1, AMPD2, AMPD3, AMPH, ANAPC1, ANAPC10, ANAPC11, ANAPC15, ANAPC16, ANAPC2, ANAPC4, ANAPC5, ANAPC7, ANG, ANGEL1, ANK1, ANK2, ANK3, ANKFY1, ANKLE1, ANKRA2, ANKRD1, ANKRD11, ANKRD12, ANKRD2, ANKRD23, ANKRD27, ANKRD28, ANKRD33, ANKRD37, ANKRD9, ANKS1A, ANKS1B, ANLN, ANO6, ANO7, ANXA1, ANXA11, ANXA2, ANXA5, ANXA8, ANXA9, AOX1, AP1AR, AP1B1, AP1G1, AP1M1, AP1M2, AP1S1, AP1S2, AP1S3, AP2A1, AP2A2, AP2B1, AP2M1, AP2S1, AP4B1, AP4M1, AP5M1, AP5S1, APAF1, APBA1, APBB1IP, APBB3, APC, APC2, APEH, APIP, APLF, APOA1, APOA2, APOA4, APOB, APOBEC3G, APOBEC3H, APOO, APP, APPL1, APRT, AR, ARAF, ARAP1, ARC, ARCN1, AREL1, ARF1, ARF4, ARF6, ARFGAP1, ARFGAP2, ARFGAP3, ARFGEF1, ARFGEF2, ARFIP1, ARFIP2, ARFRP1, ARG1, ARGLU1, ARHGAP1, ARHGAP10, ARHGAP11A, ARHGAP11B, ARHGAP15, ARHGAP17, ARHGAP18, ARHGAP19, ARHGAP20, ARHGAP21, ARHGAP22, ARHGAP23, ARHGAP26, ARHGAP27, ARHGAP28, ARHGAP29, ARHGAP30, ARHGAP31, ARHGAP32, ARHGAP33, ARHGAP35, ARHGAP39, ARHGAP4, ARHGAP40, ARHGAP44, ARHGAP45, ARHGAP5, ARHGAP6, ARHGAP8, ARHGAP9, ARHGDIA, ARHGDIB, ARHGDIG, ARHGEF1, ARHGEF10, ARHGEF10L, ARHGEF11, ARHGEF12, ARHGEF15, ARHGEF16, ARHGEF17, ARHGEF18, ARHGEF19, ARHGEF2, ARHGEF25, ARHGEF26, ARHGEF28, ARHGEF3, ARHGEF4, ARHGEF40, ARHGEF5, ARHGEF6, ARHGEF7, ARHGEF9, ARID1B, ARID3A, ARID4B, ARIH1, ARL1, ARL13B, ARL14EP, ARL2, ARL2BP, ARL4A, ARL4C, ARL6IP1, ARL8B, ARMC1, ARMC5, ARMC6, ARMC8, ARMCX3, ARMH3, ARPC1A, ARPC1B, ARPC2, ARPC3, ARPC4, ARPC5, ARRB1, ARRB2, ART4, AS3MT, ASAP1, ASAP2, ASAP3, ASB1, ASB10, ASB11, ASB12, ASB13, ASB14, ASB15, ASB16, ASB17, ASB18, ASB2, ASB3, ASB4, ASB5, ASB6, ASB7, ASB8, ASB9, ASCC3, ASF1B, ASL, ASMT, ASMTL, ASNS, ASPA, ASPG, ASPSCR1, ASRGL1, ASS1, ATAD1, ATAT1, ATF4, ATF5, ATF6, ATF6B, ATF7IP, ATG10, ATG101, ATG12, ATG13, ATG14, ATG16L1, ATG16L2, ATG3, ATG4B, ATG5, ATG7, ATIC, ATM, ATOX1, ATP12A, ATP23, ATP6V0A1, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1C1, ATP6V1C2, ATP6V1D, ATP6V1E1, ATP6V1E2, ATP6V1F, ATP6V1G1, ATP6V1G2, ATP6V1G3, ATP6V1H, ATP7A, ATP8A1, ATP8B1, ATP8B2, ATPAF2, ATXN1, ATXN10, ATXN2, ATXN2L, ATXN3, ATXN3L, ATXN7, AURKA, AURKB, AVEN, AVP, AXIN1, AXIN2, AZIN1, AZIN2, B2M, B4GALT3, B9D1, B9D2, BAALC, BAAT, BABAM1, BABAM2, BACH1, BACH2, BAD, BAG1, BAG2, BAG3, BAG4, BAG5, BAG6, BAIAP2, BAIAP2L1, BAIAP2L2, BAIAP3, BAK1, BANF1, BAP1, BARX2, BATF3, BAX, BAZ2A, BBC3, BBIP1, BBOX1, BBS1, BBS2, BBS4, BBS5, BBS7, BBS9, BCAP31, BCAR1, BCAT1, BCCIP, BCDIN3D, BCL10, BCL11A, BCL2, BCL2A1, BCL2L1, BCL2L10, BCL2L11, BCL2L14, BCL2L15, BCL2L2, BCL3, BCO1, BCR, BDH2, BDP1, BECN1, BEST1, BET1L, BEX3, BEX4, BHMT, BHMT2, BICD1, BICD2, BID, BIN1, BIRC2, BIRC3, BIRC5, BIRC6, BIRC7, BLID, BLK, BLM, BLMH, BLNK, BLOC1S1, BLOC1S2, BLOC1S3, BLOC1S4, BLOC1S6, BLTP3B, BLVRA, BLVRB, BMF, BMI1, BMT2, BMX, BNIP2, BNIPL, BOLA2, BOLA2B, BOLA3, BORA, BORCS8-MEF2B, BPGM, BPIFB4, BPNT1, BPNT2, BRAF, BRAP, BRCA2, BRCC3, BRD7, BRF1, BRK1, BRPF1, BRPF3, BRWD1, BTBD1, BTBD2, BTBD3, BTBD6, BTF3, BTG2, BTK, BTRC, BUB1, BUB1B, BUB3, BYSL, C10orf90, C11orf65, C14orf119, C15orf39, C16orf46, C16orf89, C17orf49, C17orf75, C19orf12, C19orf33, C1orf116, C1orf198, C1orf43, C1QBP, C2CD2, C2CD3, C2CD4C, C2CD5, C4orf46, C9orf72, C9orf78, CA1, CA13, CA2, CA3, CA6, CA7, CAB39, CAB39L, CABIN1, CABLES1, CABP4, CABP5, CABYR, CACNB3, CACNB4, CACTIN, CACYBP, CAD, CADPS, CALB1, CALB2, CALCOCO1, CALCOCO2, CALD1, CALM1, CALR, CAMK1, CAMK2A, CAMK2B, CAMK2D, CAMK2G, CAMK2N2, CAMKK1, CAMKK2, CAMKMT, CAMSAP2, CAMTA1, CAND1, CAND2, CAPG, CAPN1, CAPN10, CAPN2, CAPN3, CAPN7, CAPNS1, CAPNS2, CAPRIN1, CAPRIN2, CAPS, CAPZA1, CAPZA2, CAPZA3, CAPZB, CARD11, CARD14, CARD19, CARD8, CARD9, CARHSP1, CARM1, CARMIL1, CARNMT1, CARNS1, CARS1, CASC3, CASK, CASP1, CASP10, CASP14, CASP2, CASP3, CASP4, CASP5, CASP6, CASP7, CASP8, CASP9, CAST, CASTOR1, CASTOR2, CASTOR3P, CASZ1, CAT, CAVIN1, CAVIN2, CAVIN3, CAVIN4, CBL, CBLB, CBLL1, CBR1, CBR3, CBS, CBX7, CBY1, CC2D1A, CC2D1B, CC2D2A, CCDC106, CCDC110, CCDC124, CCDC13, CCDC134, CCDC22, CCDC39, CCDC43, CCDC50, CCDC6, CCDC66, CCDC8, CCDC88A, CCDC88B, CCDC91, CCHCR1, CCKAR, CCL3, CCN1, CCN4, CCNA1, CCNA2, CCNB1, CCNB2, CCND1, CCND2, CCND3, CCNE1, CCNE2, CCNF, CCNT1, CCNT2, CCP110, CCR10, CCR4, CCS, CCT2, CCT3, CCT4, CCT5, CCT6A, CCT6B, CCT7, CCT8, CCZ1, CD109, CD151, CD163, CD1B, CD28, CD2BP2, CD3G, CD44, CDA, CDAN1, CDC14A, CDC16, CDC20, CDC23, CDC25A, CDC25B, CDC25C, CDC26, CDC27, CDC34, CDC37, CDC37L1, CDC42, CDC42BPA, CDC42BPB, CDC42BPG, CDC42EP1, CDC42EP2, CDC42EP3, CDC42EP4, CDC42EP5, CDC6, CDC73, CDCA2, CDCA3, CDCA4, CDCA5, CDCA7, CDCA7L, CDCA8, CDH1, CDK1, CDK13, CDK14, CDK15, CDK16, CDK19, CDK2, CDK2AP1, CDK4, CDK5, CDK5R1, CDK5RAP1, CDK5RAP2, CDK5RAP3, CDK6, CDK7, CDKN1A, CDKN1B, CDKN2A, CDKN2B, CDKN2C, CDKN2D, CDKN3, CDO1, CDS2, CDV3, CEACAM7, CELA2A, CEMIP2, CENPA, CENPC, CENPE, CENPF, CENPH, CENPI, CENPJ, CENPK, CENPL, CENPM, CENPN, CENPO, CENPP, CENPQ, CENPS, CENPT, CENPU, CENPV, CENPX, CEP131, CEP135, CEP152, CEP162, CEP164, CEP170, CEP192, CEP250, CEP290, CEP295, CEP295NL, CEP41, CEP43, CEP57, CEP63, CEP68, CEP70, CEP72, CEP76, CEP78, CEP83, CEP85, CEP89, CEP97, CERKL, CERT1, CES1, CES2, CES3, CETN1, CETN2, CFAP157, CFAP298, CFAP410, CFAP418, CFL1, CFLAR, CFTR, CGAS, CH25H, CHAC1, CHAC2, CHAT, CHCHD1, CHCHD6, CHD1L, CHD5, CHD9, CHEK1, CHKA, CHKB, CHM, CHML, CHMP1A, CHMP1B, CHMP2A, CHMP2B, CHMP3, CHMP4A, CHMP4B, CHMP4C, CHMP5, CHMP6, CHMP7, CHN1, CHN2, CHODL, CHP2, CHPF, CHST2, CHTF18, CHUK, CIAO2A, CIAO2B, CIDEA, CIDEB, CIDEC, CIITA, CILK1, CIP2A, CIPC, CISH, CIT, CITED1, CITED2, CKAP2L, CKAP5, CKB, CKM, CLASP1, CLASP2, CLC, CLCA2, CLCN5, CLDN20, CLEC16A, CLEC5A, CLIC2, CLIC3, CLIC4, CLINT1, CLIP1, CLIP3, CLN3, CLN5, CLNS1A, CLOCK, CLP1, CLPX, CLTA, CLTB, CLTC, CLTCL1, CLU, CMA1, CMBL, CMIP, CMPK1, CMTM3, CMYA5, CNBD2, CNBP, CNDP1, CNDP2, CNEP1R1, CNN3, CNOT1, CNOT10, CNOT11, CNOT2, CNOT3, CNOT4, CNOT6, CNOT6L, CNOT7, CNOT8, CNOT9, CNTLN, CNTRL, COA1, COG3, COG4, COG5, COIL, COL21A1, COMMD1, COMMD3-BMI1, COMMD4, COMMD5, COMMD8, COMMD9, COMT, COP1, COPA, COPB1, COPB2, COPE, COPG1, COPG2, COPRS, COPS2, COPS3, COPS4, COPS5, COPS6, COPS7A, COPS7B, COPS8, COPZ1, COPZ2, COQ8B, CORO1A, CORO1B, CORO7, COTL1, COX10, COX19, COX4I1, CPEB1, CPEB3, CPLX1, CPLX2, CPLX3, CPN1, CPNE1, CPNE3, CPO, CPOX, CPPED1, CPTP, CRABP1, CRABP2, CRACD, CRADD, CRAT, CRBN, CRCP, CREB3, CREB3L1, CREB3L3, CREBBP, CRK, CRKL, CRLF1, CRLF3, CRMP1, CROCC, CROT, CRPPA, CRTC1, CRTC3, CRY2, CRYAA, CRYAB, CRYL1, CRYM, CRYZ, CRYZL1, CSDE1, CSE1L, CSK, CSN2, CSN3, CSNK1A1, CSNK1A1L, CSNK1D, CSNK1E, CSNK1G1, CSNK1G2, CSNK2A1, CSNK2A2, CSNK2A3, CSNK2B, CSRP3, CST6, CSTA, CSTB, CSTP1, CTC1, CTCFL, CTH, CTIF, CTNNA1, CTNNA2, CTNNAL1, CTNNB1, CTNNBIP1, CTNNBL1, CTNND1, CTPS1, CTPS2, CTSG, CTSH, CTTN, CTU1, CTU2, CUBN, CUEDC2, CUL1, CUL2, CUL3, CUL4B, CUL5, CUL7, CUL9, CUTC, CUX1, CWC22, CXXC1, CXXC5, CYB5A, CYB5R1, CYB5R3, CYCS, CYFIP1, CYFIP2, CYGB, CYLD, CYS1, CYTH1, CYTH2, CYTH3, CYTH4, CYTIP, DAAM1, DAB1, DAB2, DAB2IP, DACH1, DACT1, DAG1, DAO, DAOA, DAP, DAPK3, DAPP1, DARS1, DAXX, DAZAP1, DBNL, DBT, DCAF12, DCAF13, DCAF17, DCAF6, DCAF7, DCAF8, DCC, DCDC2, DCK, DCP1A, DCP1B, DCP2, DCPS, DCT, DCTD, DCTN1, DCTN2, DCTN3, DCTN4, DCTN5, DCTN6, DCTPP1, DCUN1D1, DCUN1D3, DCX, DCXR, DDAH1, DDC, DDHD1, DDHD2, DDI2, DDIT3, DDIT4, DDO, DDX1, DDX17, DDX20, DDX21, DDX28, DDX3X, DDX3Y, DDX41, DDX42, DDX5, DDX53, DDX55, DDX56, DDX6, DDX60, DECR1, DECR2, DEF6, DELE1, DENND1A, DENND1B, DENND1C, DENND2A, DENND2D, DENND3, DENND4A, DENND4B, DENND4C, DENND5A, DENND5B, DENND6A, DENND6B, DEPDC5, DERA, DES, DESI1, DFFA, DFFB, DGAT2, DGCR8, DGKA, DGKB, DGKD, DGKE, DGKG, DGKI, DGKQ, DGKZ, DGUOK, DHFR, DHFR2, DHODH, DHPS, DHRS4, DHX30, DHX36, DHX8, DHX9, DIABLO, DIAPH1, DIAPH2, DIAPH3, DICER1, DIMT1, DIS3, DIS3L, DISC1, DIXDC1, DLC1, DLEC1, DLG1, DLG2, DLG3, DLG4, DLGAP5, DLST, DLX1, DMAP1, DMC1, DMD, DMP1, DMPK, DMTF1, DMTN, DNAAF1, DNAAF11, DNAAF2, DNAAF4, DNAH7, DNAJA1, DNAJA2, DNAJA3, DNAJA4, DNAJB1, DNAJB13, DNAJB2, DNAJB4, DNAJB5, DNAJB6, DNAJB8, DNAJC13, DNAJC2, DNAJC21, DNAJC3, DNAJC5, DNAJC6, DNAJC7, DNAJC8, DNAJC9, DNLZ, DNM1L, DNM2, DNMBP, DNMT3L, DNPEP, DNPH1, DNTT, DOCK1, DOCK10, DOCK11, DOCK2, DOCK3, DOCK4, DOCK5, DOCK6, DOCK8, DOCK9, DOHH, DOK1, DOK2, DOK4, DOK5, DOK6, DOP1A, DOP1B, DPF2, DPH1, DPH2, DPH3, DPH5, DPH6, DPP3, DPP8, DPP9, DPYD, DPYS, DPYSL2, DPYSL3, DPYSL4, DPYSL5, DRC1, DRC3, DRG1, DRG2, DROSHA, DSG1, DSG3, DSN1, DST, DTL, DTNBP1, DTX1, DTX3L, DTX4, DTYMK, DUOX2, DUOXA2, DUS2, DUSP10, DUSP12, DUSP15, DUSP16, DUSP22, DUSP23, DUSP3, DUSP6, DUSP7, DUSP9, DUX4, DVL1, DVL1P1, DVL2, DVL3, DXO, DYNC1H1, DYNC1I1, DYNC1I2, DYNC1LI1, DYNC1LI2, DYNC2I2, DYNC2LI1, DYNLL1, DYNLL2, DYRK2, DYRK3, E2F8, ECD, ECH1, ECHDC1, ECI2, ECSCR, ECSIT, ECT2, EDARADD, EDC3, EDC4, EDF1, EEA1, EED, EEF1A1, EEF1AKMT1, EEF1AKMT2, EEF1AKMT3, EEF1B2, EEF1D, EEF1E1, EEF1G, EEF2, EEF2K, EEF2KMT, EFL1, EFR3A, EFR3B, EFTUD2, EGLN1, EGLN3, EHBP1, EHD2, EHD3, EHHADH, EI24, EIF1AD, EIF1AX, EIF2A, EIF2AK1, EIF2AK2, EIF2AK3, EIF2AK4, EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5, EIF2D, EIF2S1, EIF2S2, EIF2S3, EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L, EIF3M, EIF4A1, EIF4A2, EIF4A3, EIF4B, EIF4E, EIF4E2, EIF4E3, EIF4EBP1, EIF4ENIF1, EIF4G1, EIF4G2, EIF4G3, EIF4H, EIF5, EIF5A, EIF5A2, EIF5B, EIF6, ELAC1, ELAC2, ELANE, ELAVL1, ELF2, ELF3, ELK4, ELL, ELL3, ELMO1, ELMO2, ELOB, ELOC, ELP1, ELP2, ELP3, ELP5, ELP6, EMD, EML1, EML4, ENAH, ENDOD1, ENGASE, ENO1, ENO2, ENO3, ENOPH1, ENOX2, EP300, EPAS1, EPB41, EPB41L1, EPB41L2, EPB41L3, EPB41L4B, EPB41L5, EPHA3, EPHB1, EPHB2, EPHB3, EPHB4, EPHB6, EPHX2, EPM2A, EPN1, EPN2, EPRS1, EPS15, EPS15L1, EPS8L1, EPS8L2, ERAL1, ERAP1, ERBB2, ERBB4, ERCC2, ERCC6L, ERCC6L2, ERF, ERG, ERLIN2, ERMAP, ERN2, ERRFI1, ESD, ESPL1, ESR1, ESRRB, ESYT2, ETAA1, ETF1, ETNK1, ETNK2, ETS2, ETV6, EVI5, EVL, EVPL, EXO5, EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7, EXOC8, EXOSC1, EXOSC10, EXOSC2, EXOSC3, EXOSC4, EXOSC5, EXOSC6, EXOSC7, EXOSC8, EXOSC9, EXTL2, EYA2, EZHIP, EZR, F10, FAAP100, FAAP20, FAAP24, FABP1, FABP12, FABP2, FABP3, FABP4, FABP5, FABP5P3, FABP6, FABP7, FABP9, FADD, FAF1, FAH, FAHD1, FAM110A, FAM110B, FAM114A1, FAM120A, FAM131B, FAM13A, FAM13B, FAM162A, FAM217B, FAM72A, FAM72B, FAM72C, FAM72D, FAM83B, FAM83D, FAM83G, FAN1, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, FANK1, FARP1, FARP2, FARSA, FARSB, FAS, FASN, FAT1, FAU, FBF1, FBLIM1, FBLP1, FBP1, FBP2, FBXL12, FBXL13, FBXL14, FBXL15, FBXL16, FBXL17, FBXL18, FBXL19, FBXL20, FBXL21P, FBXL22, FBXL3, FBXL4, FBXL5, FBXL7, FBXL8, FBXO10, FBXO11, FBXO15, FBXO17, FBXO2, FBXO21, FBXO22, FBXO27, FBXO3, FBXO30, FBXO31, FBXO32, FBXO38, FBXO4, FBXO40, FBXO41, FBXO44, FBXO5, FBXO6, FBXO7, FBXO9, FBXW10, FBXW11, FBXW12, FBXW2, FBXW4, FBXW5, FBXW7, FBXW8, FBXW9, FCHO1, FCHO2, FCSK, FDPS, FEM1A, FEM1B, FEM1C, FER, FERMT1, FERMT2, FES, FEZF1, FGD1, FGD2, FGD3, FGD4, FGD5, FGF1, FGF13, FGFR1, FGFR1OP2, FGR, FH, FHIT, FHL1, FHOD1, FHOD3, FILIP1, FIP1L1, FIRRM, FIS1, FKBP1A, FKBP4, FKBP5, FKBP6, FKBP8, FKBPL, FKRP, FLAD1, FLCN, FLG, FLI1, FLII, FLNA, FLNB, FLNC, FLRT3, FLT3LG, FLT4, FLYWCH1, FMN2, FMNL1, FMNL2, FMNL3, FMO5, FMR1, FN3K, FN3KRP, FNBP1, FNBP1L, FNDC3A, FNIP1, FNIP2, FNTA, FNTB, FOCAD, FOS, FOSB, FOXC1, FOXO1, FOXO3, FOXO3B, FOXO4, FOXP3, FPGS, FPGT, FRAT1, FRAT2, FRK, FRMD7, FRMD8, FRMPD1, FRS2, FSCN1, FTCD, FTH1, FTL, FTO, FTSJ1, FUOM, FXN, FXR1, FXR2, FYB1, FYN, FZR1, G2E3, G3BP1, G3BP2, G6PD, GAB1, GAB2, GABARAP, GABARAPL1, GABARAPL2, GABRA5, GAD2, GADL1, GAK, GALE, GALK1, GALK2, GALT, GAMT, GAN, GAPDH, GAPDHS, GAPVD1, GARRE1, GARS1, GART, GAS2, GAS8, GBA2, GBA3, GBE1, GBF1, GBP1, GBP2, GBP3, GBP4, GC, GCA, GCC1, GCC2, GCFC2, GCH1, GCHFR, GCK, GCKR, GCLC, GCLM, GCN1, GDA, GDAP1, GDAP1L1, GDI1, GDI2, GEMIN2, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, GET4, GFAP, GFER, GFPT1, GFPT2, GFRA3, GFUS, GGA1, GGACT, GGCT, GGPS1, GHR, GID4, GID8, GIGYF1, GIGYF2, GIMAP4, GIMAP6, GIMAP8, GIPC1, GIT1, GJA1, GK, GK2, GLE1, GLI1, GLI2, GLI3, GLMP, GLO1, GLRX, GLRX3, GLS, GLT1D1, GLTP, GLTPD2, GLUL, GLYCTK, GLYR1, GM2A, GMDS, GMEB2, GMIP, GMNN, GMPPA, GMPPB, GMPR, GMPR2, GMPS, GNA13, GNAI1, GNAI2, GNAS, GNAT1, GNB1, GNB2, GNB3, GNB4, GNB5, GNE, GNL3L, GNMT, GNPAT, GNPDA1, GNPDA2, GNPNAT1, GOLGA1, GOLGA3, GOLGA4, GOLGA8A, GOLGA8B, GOLGB1, GOLPH3, GOLPH3L, GOLT1A, GOLT1B, GON7, GORAB, GOSR1, GOSR2, GOT1, GOT1L1, GPAA1, GPATCH3, GPBP1, GPC1, GPCPD1, GPD1, GPD1L, GPER1, GPHN, GPI, GPN1, GPR142, GPR20, GPR63, GPRASP1, GPRASP2, GPRASP3, GPRC5B, GPS1, GPS2, GPSM1, GPSM2, GPT, GPX1, GPX2, GPX4, GRAMD1A, GRAP, GRAP2, GRAPL, GRB10, GRB14, GRB2, GRB7, GRHPR, GRIA1, GRIP1, GRIP2, GRIPAP1, GRK2, GRK3, GRK4, GRK5, GRWD1, GSDMA, GSDMC, GSDMD, GSDME, GSK3A, GSK3B, GSN, GSPT1, GSPT2, GSR, GSS, GSTA1, GSTA2, GSTA3, GSTA4, GSTA5, GSTK1, GSTM1, GSTM2, GSTM3, GSTM4, GSTM5, GSTO1, GSTO2, GSTP1, GSTT1, GSTT2, GSTT2B, GSTT4, GSTZ1, GTF2A1, GTF2E1, GTF2E2, GTF2IRD1, GTPBP1, GTPBP4, GTSE1, GUCY1A1, GUCY1A2, GUCY1B1, GUCY1B2, GUK1, GVINP1, GYG1, GYG2, GYPA, GYS1, GYS2, GZMB, H2BC10, H2BC11, H2BC12, H2BC12L, H2BC13, H2BC14, H2BC15, H2BC17, H2BC18, H2BC21, H2BC26, H2BC3, H2BC4, H2BC5, H2BC6, H2BC7, H2BC8, H2BC9, HAAO, HABP4, HACL1, HAGH, HAL, HAO1, HAO2, HAP1, HARBI1, HARS1, HARS2, HAUS1, HAUS2, HAUS3, HAUS4, HAUS5, HAUS6, HAUS7, HAUS8, HBA2, HBB, HBD, HBE1, HBG1, HBG2, HBS1L, HCCS, HCFC2, HCK, HCLS1, HDAC1, HDAC10, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDC, HDGFL3, HEATR5A, HEATR5B, HECTD2, HECW1, HELB, HELZ, HELZ2, HERC1, HERC2, HERC4, HERC5, HERC6, HEXA, HEXIM2, HGD, HGFAC, HGS, HID1, HIF1A, HIF1AN, HIF3A, HIKESHI, HILPDA, HINT1, HIP1, HIP1R, HIPK1, HIPK3, HIVEP1, HJURP, HK1, HK2, HK3, HKDC1, HLCS, HMBOX1, HMBS, HMGA1, HMGCL, HMGCLL1, HMGCS1, HMGN3, HMMR, HMOX1, HNF4G, HNMT, HNRNPA1, HNRNPC, HNRNPD, HNRNPDL, HNRNPF, HNRNPH1, HNRNPH2, HNRNPU, HOMER1, HOMER2, HOMER3, HOMEZ, HOOK2, HORMAD2, HOXB5, HOXB7, HOXC11, HOXC6, HOXD10, HPCA, HPD, HPGD, HPGDS, HPRT1, HPS1, HPS3, HPS4, HPS5, HPS6, HRAS, HRH1, HSBP1, HSBP1L1, HSCB, HSD17B1, HSD17B11, HSD17B13, HSD17B14, HSD17B4, HSF1, HSF2BP, HSFY1, HSFY2, HSP90AA1, HSP90AA2P, HSP90AA4P, HSP90AB1, HSP90AB2P, HSP90AB3P, HSP90AB4P, HSP90B1, HSPA13, HSPA14, HSPA1A, HSPA1B, HSPA1L, HSPA2, HSPA4, HSPA4L, HSPA5, HSPA6, HSPA8, HSPB1, HSPB2, HSPB6, HSPB8, HSPB9, HSPD1, HSPH1, HTATIP2, HTRA1, HTRA2, HTT, HUS1, HUWE1, HYAL2, HYCC1, HYCC2, HYLS1, IARS1, ICA1, ICE2, ID2, IDE, IDH1, IDH2, IDI1, IDI2, IDO1, IDO2, IER3, IFI16, IFI30, IFI35, IFIH1, IFIT1, IFIT1B, IFIT2, IFIT3, IFIT5, IFITM5, IFT88, IFTAP, IGBP1, IGBP1C, IGF2BP1, IGF2BP2, IGF2BP3, IKBKB, IKBKE, IKBKG, IKZF1, IKZF3, IL10RA, IL12B, IL15, IL16, IL18, IL1A, IL1B, IL1RL1, IL1RN, IL22RA2, IL26, IL27, IL2RB, IL2RG, IL32, IL36G, IL37, IL7R, ILDR1, ILF2, ILF3, ILK, ILRUN, IMP3, IMPA1, IMPA2, IMPDH1, IMPDH2, INCENP, ING4, INMT, INO80, INPP1, INPP4A, INPP4B, INPP5B, INPP5D, INPP5E, INPP5J, INPP5K, INPPL1, INTS11, INTS5, INTS9, IP6K1, IP6K3, IPO11, IPO5, IPO7, IPO8, IPO9, IPPK, IQCB1, IQCG, IQGAP1, IQGAP2, IQGAP3, IQSEC3, IRAK1, IRAK2, IRAK4, IREB2, IRF1, IRF2, IRF3, IRF4, IRF5, IRF6, IRF7, IRF8, IRF9, IRGM, IRS1, IRS2, IRS4, ISCU, ISG15, IST1, ISYNA1, ITCH, ITFG2, ITGAV, ITGB1BP1, ITGB3BP, ITK, ITPA, ITPK1, ITPKA, ITPKB, ITPKC, ITPRID2, ITSN1, ITSN2, IVL, IVNS1ABP, JADE1, JAK1, JAK2, JAK3, JAZF1, JMJD4, JMJD6, JMJD7, JOSD1, JOSD2, JPT1, JPT2, JUP, KALRN, KANK4, KANSL2, KARS1, KAT2B, KAT5, KAT6A, KAT7, KATNB1, KAZN, KBTBD13, KBTBD6, KBTBD7, KBTBD8, KCMF1, KCNA1, KCNA6, KCNAB1, KCNAB2, KCNIP3, KCNIP4, KCNK2, KCNN4, KCNS3, KCTD1, KCTD10, KCTD13, KCTD5, KCTD6, KCTD7, KDM4A, KDM4B, KDM5B, KDM5C, KDM8, KEAP1, KEL, KHDRBS1, KHK, KHSRP, KIAA0753, KIDINS220, KIF11, KIF14, KIF15, KIF16B, KIF17, KIF18A, KIF18B, KIF20B, KIF21A, KIF22, KIF23, KIF24, KIF26A, KIF2A, KIF2B, KIF2C, KIF3A, KIF3B, KIF3C, KIF4A, KIF4B, KIF5A, KIF5B, KIFAP3, KLC1, KLC2, KLF11, KLF12, KLF14, KLF4, KLF6, KLF7, KLF8, KLF9, KLHDC1, KLHDC3, KLHDC8B, KLHL11, KLHL12, KLHL13, KLHL14, KLHL2, KLHL20, KLHL21, KLHL22, KLHL25, KLHL3, KLHL41, KLHL42, KLHL5, KLHL7, KLHL9, KLK5, KMO, KMT2A, KMT2C, KMT5A, KNL1, KNTC1, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, KPNA6, KPNA7, KPNB1, KRAS, KRT1, KRT10, KRT12, KRT13, KRT14, KRT15, KRT16, KRT17, KRT18, KRT19, KRT2, KRT20, KRT23, KRT24, KRT25, KRT26, KRT27, KRT28, KRT3, KRT31, KRT32, KRT33A, KRT33B, KRT34, KRT35, KRT36, KRT37, KRT38, KRT39, KRT4, KRT40, KRT5, KRT6A, KRT6B, KRT6C, KRT7, KRT71, KRT72, KRT73, KRT74, KRT75, KRT76, KRT77, KRT78, KRT79, KRT8, KRT80, KRT81, KRT82, KRT83, KRT84, KRT85, KRT86, KRT9, KRTAP1-1, KRTAP1-3, KRTAP1-4, KRTAP1-5, KRTAP10-1, KRTAP10-10, KRTAP10-11, KRTAP10-12, KRTAP10-2, KRTAP10-3, KRTAP10-4, KRTAP10-5, KRTAP10-6, KRTAP10-7, KRTAP10-8, KRTAP10-9, KRTAP11-1, KRTAP12-1, KRTAP12-2, KRTAP12-3, KRTAP12-4, KRTAP13-1, KRTAP13-2, KRTAP13-3, KRTAP13-4, KRTAP15-1, KRTAP16-1, KRTAP17-1, KRTAP19-1, KRTAP19-2, KRTAP19-3, KRTAP19-4, KRTAP19-5, KRTAP19-6, KRTAP19-7, KRTAP19-8, KRTAP2-1, KRTAP2-2, KRTAP2-3, KRTAP2-4, KRTAP20-1, KRTAP20-2, KRTAP21-1, KRTAP21-2, KRTAP21-3, KRTAP22-1, KRTAP23-1, KRTAP24-1, KRTAP25-1, KRTAP26-1, KRTAP27-1, KRTAP29-1, KRTAP3-1, KRTAP3-2, KRTAP3-3, KRTAP4-1, KRTAP4-11, KRTAP4-12, KRTAP4-16, KRTAP4-2, KRTAP4-3, KRTAP4-4, KRTAP4-5, KRTAP4-6, KRTAP4-7, KRTAP4-8, KRTAP4-9, KRTAP5-1, KRTAP5-10, KRTAP5-11, KRTAP5-2, KRTAP5-3, KRTAP5-4, KRTAP5-5, KRTAP5-6, KRTAP5-7, KRTAP5-8, KRTAP5-9, KRTAP6-1, KRTAP6-2, KRTAP6-3, KRTAP8-1, KRTAP9-1, KRTAP9-2, KRTAP9-3, KRTAP9-4, KRTAP9-6, KRTAP9-7, KRTAP9-8, KRTAP9-9, KSR1, KSR2, KYAT1, KYNU, LACTB, LAMP1, LAMTOR5, LANCL2, LAPTM5, LARP1, LARP1B, LARP4, LARP4B, LARP7, LARS1, LATS1, LATS2, LAX1, LCE1A, LCE3D, LCK, LCLAT1, LCMT1, LCP1, LCP2, LDHA, LDHB, LDHC, LDLRAP1, LEP, LGALS1, LGALS3, LGALS4, LGALS8, LGALS9, LGALS9B, LGALS9C, LGTN, LHPP, LIF, LIMA1, LIMD1, LIMD2, LIMK1, LIMS1, LIMS2, LIN28A, LIN28B, LIPA, LIPE, LLGL2, LMLN, LMNA, LMO7, LMOD1, LNPEP, LOC100996750, LONP1, LONP2, LONRF1, LORICRIN, LPIN1, LPIN2, LPP, LPXN, LRBA, LRCH3, LRGUK, LRR1, LRRC1, LRRC14, LRRC23, LRRC25, LRRC41, LRRC45, LRRC7, LRRFIP1, LRRK1, LRRK2, LRSAM1, LSAMP, LSG1, LSM1, LSM14A, LSM2, LSM3, LSM4, LSM5, LSM6, LSM7, LST1, LTA4H, LTN1, LTV1, LURAP1, LYN, LYPLA1, LYPLA2, LYPLAL1, LYST, LZTFL1, LZTS2, MAD1L1, MAD2L1, MADD, MAEA, MAF1, MAGEA10, MAGEA11, MAGEC2, MAGED1, MAGED2, MAGEE1, MAGEL2, MAGOH, MAGOHB, MAL, MALSU1, MALT1, MAN1A1, MAN2C1, MANF, MAOA, MAP1A, MAP1B, MAP1LC3A, MAP1LC3B, MAP1LC3C, MAP1S, MAP2, MAP2K1, MAP2K2, MAP2K3, MAP2K4, MAP2K6, MAP2K7, MAP3K1, MAP3K11, MAP3K12, MAP3K14, MAP3K2, MAP3K20, MAP3K3, MAP3K5, MAP3K7, MAP3K7CL, MAP3K8, MAP4, MAP4K5, MAP7, MAPK1, MAPK10, MAPK11, MAPK12, MAPK13, MAPK14, MAPK3, MAPK4, MAPK6, MAPK7, MAPK8, MAPK8IP1, MAPK9, MAPKAP1, MAPKAPK2, MAPKAPK3, MAPKAPK5, MAPRE1, MAPT, MARCHF2, MARCHF7, MARK3, MARK4, MARS1, MAS1L, MASP1, MAST1, MAT1A, MAT2A, MAT2B, MATK, MB, MBD2, MBIP, MBLAC1, MBNL1, MBNL3, MBP, MCC, MCCC1, MCCC2, MCF2, MCF2L, MCL1, MCM2, MCM3AP, MCM7, MCMBP, MCTP2, MDH1, MDM1, MDM2, MDN1, ME1, MEAK7, MECOM, MECP2, MED27, MEF2A, MEF2B, MEF2C, MEFV, MEIG1, MEMO1, MEN1, METAP1, METAP2, METTL1, METTL13, METTL18, METTL21A, METTL21C, METTL21EP, METTL3, METTL4, METTL5, MEX3A, MEX3B, MFN2, MGLL, MGRN1, MIB1, MIB2, MICAL1, MICAL3, MICALL2, MID1, MID1IP1, MIDN, MIEN1, MIF, MIF4GD, MINK1, MIOS, MIOX, MIS12, MIS18A, MITF, MKKS, MKLN1, MKNK1, MKRN1, MKS1, MLC1, MLIP, MLKL, MLLT1, MLLT10, MLLT11, MLLT3, MLNR, MLPH, MLST8, MLX, MLXIPL, MLYCD, MMAA, MMACHC, MMADHC, MMP14, MMP3, MMS19, MMS22L, MNDA, MNX1, MOAP1, MOB1A, MOB1B, MOB2, MOCOS, MOCS1, MOCS2, MOCS3, MON1A, MON2, MORC2, MOS, MOV10, MOV10L1, MPG, MPHOSPH6, MPHOSPH8, MPI, MPIG6B, MPP4, MPRIP, MPV17, MRE11, MRI1, MRPL28, MRPL38, MRPL50, MRPS16, MRTFA, MSH6, MSI2, MSN, MSRA, MSRB1, MSRB2, MSRB3, MST1, MSTO1, MSX2, MT1A, MT2A, MT3, MTA1, MTAP, MTERF3, MTERF4, MTF1, MTFR1, MTHFD1, MTHFD1L, MTHFR, MTHFS, MTM1, MTMR1, MTMR10, MTMR12, MTMR14, MTMR2, MTMR3, MTMR4, MTMR6, MTMR7, MTMR8, MTMR9, MTO1, MTOR, MTPN, MTR, MTRR, MTTP, MUC13, MVB12A, MVB12B, MVD, MVK, MVP, MX1, MX2, MXD1, MXI1, MYB, MYBL2, MYBPC1, MYBPC2, MYBPC3, MYCBP2, MYD88, MYF6, MYH10, MYH11, MYH14, MYH15, MYH2, MYH3, MYH6, MYH8, MYH9, MYL1, MYL10, MYL11, MYL12A, MYL12B, MYL2, MYL3, MYL4, MYL5, MYL6, MYL6B, MYL7, MYL9, MYLIP, MYLK, MYLK3, MYO10, MYO19, MYO1C, MYO1F, MYO5A, MYO6, MYO7A, MYO9A, MYO9B, MYPN, MYRF, MYRIP, MYT1, MZT1, MZT2A, MZT2B, N4BP1, N4BP2, N6AMT1, NAA10, NAA11, NAA15, NAA16, NAA20, NAA25, NAA30, NAA35, NAA40, NAA50, NAA80, NABP1, NABP2, NADK, NADSYN1, NAE1, NAF1, NAGK, NAIF1, NAMPT, NANOS3, NANP, NANS, NAPA, NAPRT, NARS1, NARS2, NAT1, NAT2, NAXE, NBAS, NBEA, NBEAL1, NBEAL2, NBN, NBR1, NCALD, NCAM1, NCAPD2, NCAPG, NCAPH, NCBP1, NCBP2, NCCRP1, NCDN, NCF1, NCF2, NCF4, NCK1, NCK2, NCKAP1, NCKAP1L, NCKIPSD, NCOA1, NCOA3, NCOA6, NCOR1, NDC80, NDE1, NDEL1, NDN, NDOR1, NDRG1, NDRG2, NDRG4, NDUFA12, NDUFAF1, NDUFAF4, NDUFV1, NEB, NECAB1, NECAP1, NEDD1, NEDD4, NEDD4L, NEDD8, NEDD9, NEFL, NEIL1, NEK1, NEK2, NEK4, NEK6, NEK8, NEK9, NELFA, NEMF, NET1, NEU2, NEURL1B, NEURL2, NEURL3, NEXMIF, NF1, NF2, NFAT5, NFATC1, NFATC2, NFATC3, NFATC4, NFE2L1, NFE2L2, NFKB1, NFKB2, NFKBIA, NFKBIB, NFKBIE, NFS1, NFU1, NFX1, NGB, NGEF, NGF, NGFR, NGLY1, NHERF4, NHLRC1, NHLRC2, NIBAN1, NIBAN2, NINL, NIP7, NIPBL, NIPSNAP3A, NISCH, NIT2, NKAP, NKIRAS1, NKX3-1, NLK, NLN, NLRC3, NLRC4, NLRC5, NLRP1, NLRP10, NLRP12, NLRP2, NLRP3, NLRP4, NLRP5, NLRP6, NLRX1, NMBR, NME1, NME1-NME2, NME2, NME3, NME7, NME8, NMI, NMNAT2, NMRAL1, NMRK1, NMRK2, NMT1, NMT2, NNMT, NOB1, NOC2L, NOD1, NOD2, NOL3, NOL4L, NOP53, NOP58, NOS1, NOS1AP, NOS2, NOS3, NOSIP, NOTCH1, NOTCH3, NOTCH4, NOXA1, NPAS2, NPAS4, NPEPPS, NPHP1, NPHP3, NPHP4, NPL, NPLOC4, NPM1, NPM3, NQO1, NQO2, NR1H2, NR1H3, NR1I3, NR2F1, NR2F2, NR3C1, NR3C2, NR4A1, NR5A1, NRAS, NRDC, NRF1, NRGN, NRIP1, NRK, NRL, NRP1, NSF, NSFL1C, NSL1, NSMAF, NSUN6, NT5C, NT5C1A, NT5C1B, NT5C2, NT5C3A, NT5C3B, NT5DC3, NT5E, NTAQ1, NTMT1, NTN1, NTRK2, NUB1, NUBP1, NUBP2, NUCB2, NUDC, NUDCD1, NUDCD2, NUDT1, NUDT10, NUDT11, NUDT14, NUDT15, NUDT18, NUDT19, NUDT3, NUDT4, NUDT4B, NUDT5, NUDT7, NUF2, NUFIP2, NUMA1, NUP107, NUP133, NUP153, NUP155, NUP160, NUP188, NUP205, NUP214, NUP35, NUP37, NUP42, NUP43, NUP85, NUP88, NUP93, NUP98, NUTF2, NWD1, NXF1, NXF2, NXF2B, NXN, NXT1, NXT2, OAS1, OAS2, OAS3, OASL, OAZ1, OAZ2, OAZ3, OBSCN, OBSL1, OCRL, ODAM, ODC1, ODCP, ODF2, OFD1, OGA, OGFOD1, OGG1, OGT, OLA1, OLAH, OLFM4, OMP, OPA1, OPLAH, OPN1SW, OPRK1, OPTN, OR6B2, OR6B3, ORC1, ORC4, ORC5, ORC6, OSBP, OSBP2, OSBPL10, OSBPL11, OSBPL1A, OSBPL2, OSBPL3, OSBPL5, OSBPL6, OSBPL7, OSBPL8, OSBPL9, OSGEP, OSR1, OSTM1, OTOF, OTOG, OTUB1, OTUD3, OTUD4, OTUD5, OTUD7A, OTUD7B, OTULIN, OVGP1, OXSM, OXSR1, P2RX5, P3H2, P4HA2, P4HB, PABPC1, PABPC1L, PABPC1L2A, PABPC1L2B, PABPC3, PABPC4, PABPC4L, PABPC5, PACRG, PACS1, PACSIN1, PACSIN2, PACSIN3, PADI1, PADI2, PADI3, PADI4, PAF1, PAFAH1B1, PAFAH1B2, PAFAH1B3, PAH, PAICS, PAIP1, PAK1, PAK2, PAK3, PAK4, PAK5, PAK6, PALD1, PALLD, PAM, PAN2, PAN3, PANK1, PANK2, PANK3, PANK4, PAOX, PAPOLG, PAPSS1, PAPSS2, PARD3, PARD6A, PARD6B, PARD6G, PARG, PARK7, PARM1, PARN, PARP1, PARP10, PARP11, PARP14, PARP16, PARP4, PARP9, PARVA, PARVB, PASK, PATJ, PATL1, PAWR, PAX6, PAXBP1, PBOV1, PBXIP1, PC, PCBD1, PCBP1, PCBP2, PCBP3, PCBP4, PCCA, PCCB, PCK1, PCM1, PCMT1, PCNT, PCP4, PCTP, PCYT1A, PDAP1, PDC, PDCD10, PDCD11, PDCD4, PDCD5, PDCD6, PDCD6IP, PDCL, PDCL3, PDE10A, PDE11A, PDE12, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A, PDE6D, PDE7A, PDE7B, PDE8A, PDE8B, PDE9A, PDGFC, PDIA6, PDK1, PDK2, PDLIM3, PDLIM5, PDLIM7, PDPK1, PDPN, PDS5A, PDS5B, PDSS2, PDX1, PDXK, PDXP, PDZD11, PDZD2, PEA15, PEAK1, PEBP1, PECR, PEG10, PELI1, PELI2, PELI3, PEMT, PER1, PER2, PES1, PEX1, PEX11B, PEX12, PEX13, PEX14, PEX16, PEX19, PEX2, PEX26, PEX5, PEX5L, PEX6, PEX7, PFAS, PFDN2, PFDN4, PFDN5, PFKFB1, PFKFB2, PFKFB3, PFKFB4, PFKL, PFKM, PFKP, PFN1, PGAM1, PGAM2, PGD, PGGHG, PGK1, PGK2, PGLS, PGM1, PGM2, PGM2L1, PGM3, PGM5, PGPEP1, PGPEP1L, PGR, PHACTR1, PHAX, PHETA1, PHETA2, PHF1, PHF20, PHF7, PHGDH, PHKA1, PHKA2, PHKB, PHKG1, PHKG2, PHLDA1, PHLDB1, PHLDB2, PHLPP1, PHLPP2, PHOSPHO1, PHPT1, PHYH, PI3, PI4K2A, PI4K2B, PI4KA, PI4KB, PICALM, PICK1, PIDD1, PIGN, PIK3AP1, PIK3C2A, PIK3C2B, PIK3C2G, PIK3C3, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3R1, PIK3R2, PIK3R3, PIK3R4, PIK3R5, PIK3R6, PIKFYVE, PIM1, PIM3, PIN1, PINK1, PIP4K2A, PIP4K2B, PIP4K2C, PIP5K1A, PIP5K1B, PIP5K1C, PIP5KL1, PIPOX, PIR, PISD, PITPNA, PITPNC1, PITPNM1, PITPNM2, PITPNM3, PKD1, PKD2, PKD2L1, PKHD1L1, PKLR, PKM, PKMYT1, PKN1, PKN2, PKN3, PKNOX1, PLA2G2F, PLA2G4A, PLA2G4B, PLA2G4C, PLA2G4D, PLA2G4E, PLA2G4F, PLA2G6, PLAAT1, PLAAT2, PLAAT3, PLAAT4, PLAAT5, PLAG1, PLBD1, PLCB1, PLCB2, PLCB3, PLCB4, PLCD4, PLCE1, PLCG1, PLCG2, PLCH1, PLCZ1, PLEC, PLEK, PLEKHA1, PLEKHA3, PLEKHA5, PLEKHA7, PLEKHA8, PLEKHA8P1, PLEKHG1, PLEKHG2, PLEKHG3, PLEKHG4, PLEKHG4B, PLEKHG5, PLEKHG6, PLEKHH2, PLEKHJ1, PLIN1, PLIN2, PLIN3, PLIN4, PLIN5, PLK1, PLK2, PLK4, PLPBP, PLS1, PLS3, PLSCR1, PLSCR3, PLXNA1, PMAIP1, PMF1, PML, PMM1, PMM2, PMP2, PMP22, PMS2, PMVK, PNISR, PNMT, PNO1, PNP, PNPLA2, PNPLA4, PNPLA5, PNPLA6, PNPO, PNPT1, PNRC2, POC5, POGLUT2, POGZ, POLA1, POLA2, POLD1, POLDIP3, POLH, POLQ, POLR1B, POLR1C, POLR1D, POLR1E, POLR1G, POLR2C, POLR2D, POLR2E, POLR2F, POLR2H, POLR2K, POLR2L, POLR3A, POLR3B, POLR3C, POLR3D, POLR3E, POLR3F, POLR3G, POLR3GL, POLR3H, POLR3K, POMP, POMT2, POP1, POR, POTEKP, POU1F1, POU2AF2, POU2F3, POU5F1, POU5F1B, PPA1, PPARG, PPARGC1A, PPARGC1B, PPAT, PPCDC, PPCS, PPEF1, PPEF2, PPFIA1, PPFIA2, PPFIA3, PPFIA4, PPFIBP1, PPFIBP2, PPHLN1, PPIA, PPIB, PPID, PPIE, PPIG, PPIH, PPIL4, PPIP5K1, PPIP5K2, PPL, PPM1A, PPM1B, PPM1D, PPM1F, PPM1N, PPP1CA, PPP1CB, PPP1CC, PPP1R12A, PPP1R12B, PPP1R13B, PPP1R13L, PPP1R14A, PPP1R15A, PPP1R1B, PPP1R3C, PPP2CA, PPP2CB, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R2B, PPP2R2C, PPP2R2D, PPP2R3B, PPP2R3C, PPP2R5A, PPP2R5B, PPP2R5C, PPP2R5D, PPP2R5E, PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2, PPP4C, PPP4R3A, PPP4R4, PPP5C, PPP6C, PPP6R1, PPP6R2, PPP6R3, PPT1, PRAC1, PRAG1, PRC1, PRDM11, PRDM16, PRDX1, PRDX2, PRDX3, PRDX4, PRDX5, PRDX6, PREP, PREPL, PREX1, PREX2, PRF1, PRG1, PRG3, PRICKLE1, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKACA, PRKACB, PRKACG, PRKAG1, PRKAG2, PRKAG3, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PRKCH, PRKCI, PRKCQ, PRKCZ, PRKD1, PRKD2, PRKD3, PRKDC, PRKG1, PRKG2, PRKN, PRKRA, PRM1, PRMT1, PRMT2, PRMT3, PRMT5, PRMT7, PRMT9, PRNP, PROX1, PRPF3, PRPS1, PRPS2, PRR13, PRR5, PRR7, PRRC2A, PRRC2C, PRRX1, PRSS55, PRTFDC1, PRTN3, PRUNE1, PRUNE2, PRXL2B, PSAPL1, PSAT1, PSIP1, PSKH1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMA8, PSMB1, PSMB10, PSMB11, PSMB2, PSMB3, PSMB4, PSMB5, PSMB6, PSMB7, PSMB8, PSMB9, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMC6, PSMD1, PSMD10, PSMD11, PSMD12, PSMD13, PSMD14, PSMD2, PSMD3, PSMD4, PSMD5, PSMD6, PSMD7, PSMD8, PSMD9, PSME1, PSME2, PSME3, PSME4, PSMF1, PSMG1, PSMG2, PSPH, PSRC1, PSTPIP1, PSTPIP2, PTCD3, PTEN, PTGES2, PTGES3, PTGES3L, PTGIR, PTH2, PTHLH, PTK2, PTK2B, PTK6, PTMA, PTMAP7, PTP4A2, PTPN1, PTPN11, PTPN12, PTPN13, PTPN18, PTPN2, PTPN22, PTPN3, PTPN4, PTPN5, PTPN6, PTPN7, PTPRH, PTPRQ, PTPRR, PTPRS, PTRH2, PTS, PTTG1, PUDP, PUM1, PUM2, PUS3, PWWP3A, PXK, PXMP2, PXMP4, PXN, PYCARD, PYCR3, PYDC1, PYDC2, PYGL, PYGM, PYHIN1, PYM1, QARS1, QDPR, QKI, QPRT, RAB10, RAB11A, RAB11B, RAB11FIP1, RAB11FIP3, RAB12, RAB13, RAB14, RAB18, RAB1A, RAB1B, RAB1C, RAB21, RAB23, RAB24, RAB27A, RAB29, RAB2A, RAB31, RAB32, RAB35, RAB38, RAB39A, RAB3A, RAB3GAP1, RAB3GAP2, RAB3IL1, RAB3IP, RAB41, RAB4B, RAB5A, RAB6A, RAB6B, RAB6C, RAB6D, RAB7A, RAB8A, RAB9A, RAB9B, RABEP2, RABEPK, RABGAP1, RABGEF1, RABGGTA, RABGGTB, RABIF, RABL6, RAC1, RAC2, RAC3, RACGAP1, RACK1, RAD21, RAD23A, RAD23B, RAD51, RAD51C, RAF1, RAI14, RALBP1, RALGAPA2, RALGDS, RAN, RANBP1, RANBP10, RANBP2, RANBP9, RANGAP1, RANGRF, RAP1A, RAP1B, RAP1BL, RAP1GAP, RAP1GAP2, RAP1GDS1, RAP2A, RAP2B, RAP2C, RAPGEF1, RAPGEF2, RAPGEF4, RAPGEF6, RAPH1, RAPSN, RARA, RARS1, RASA1, RASA2, RASA3, RASA4, RASA4B, RASAL1, RASAL2, RASAL3, RASEF, RASGEF1A, RASGRF1, RASGRF2, RASGRP1, RASGRP2, RASGRP4, RASSF10, RASSF2, RASSF3, RASSF4, RASSF9, RAX, RB1, RB1CC1, RBBP4, RBBP6, RBBP7, RBCK1, RBIS, RBKS, RBL2, RBM18, RBM24, RBM38, RBM4, RBM4B, RBM8A, RBMS1, RBMS2, RBMS3, RBP1, RBP2, RBP5, RBP7, RBPMS, RBPMS2, RBSN, RBX1, RCAN3, RCC2, RCCD1, RCE1, RCHY1, RCOR3, RCSD1, RDH14, RDH8, RDM1, RECQL5, REL, RELA, RELB, RENBP, REPIN1, REPS1, REPS2, RERG, REST, RFFL, RFK, RFPL1, RFPL2, RFPL3, RFPL4A, RFPL4AL1, RFPL4B, RFXANK, RGCC, RGL1, RGL2, RGL3, RGP1, RGS1, RGS10, RGS12, RGS13, RGS2, RGS22, RGS3, RGS5, RGS6, RGS7, RHEB, RHOA, RHOB, RHOBTB3, RHOC, RHOD, RHOF, RHOG, RHOU, RHOXF1, RHPN1, RHPN2, RIC1, RIC8B, RICTOR, RIDA, RIGI, RILP, RILPL1, RILPL2, RIMKLA, RIMKLB, RIMOC1, RIMS1, RIN1, RIN2, RIN3, RING1, RINL, RINT1, RIOK1, RIOK2, RIOK3, RIOX2, RIPK1, RIPK2, RIPK3, RIT2, RLBP1, RLIM, RMDN2, RMI2, RMND5A, RMND5B, RNASEH2A, RNASEK-C17orf49, RNASEL, RND1, RND2, RND3, RNF111, RNF114, RNF115, RNF123, RNF126, RNF128, RNF13, RNF135, RNF14, RNF144B, RNF146, RNF167, RNF168, RNF169, RNF187, RNF19A, RNF19B, RNF208, RNF213, RNF216, RNF217, RNF25, RNF31, RNF32, RNF34, RNF41, RNF7, RNF8, RNH1, RNPS1, RO60, ROCK1, ROCK2, RPAP2, RPAP3, RPE, RPEL1, RPF1, RPGRIP1L, RPH3A, RPIA, RPL10, RPL10A, RPL10L, RPL11, RPL12, RPL13, RPL13A, RPL14, RPL15, RPL17, RPL18, RPL18A, RPL19, RPL21, RPL22, RPL23, RPL23A, RPL24, RPL26, RPL27, RPL27A, RPL28, RPL29, RPL3, RPL30, RPL31, RPL32, RPL34, RPL35, RPL35A, RPL36, RPL36A, RPL36A-HNRNPH2, RPL36AL, RPL37, RPL37A, RPL38, RPL39, RPL4, RPL41, RPL5, RPL6, RPL7, RPL7A, RPL8, RPL9, RPLP0, RPLP1, RPLP2, RPN1, RPP21, RPS10, RPS10-NUDT3, RPS11, RPS12, RPS13, RPS14, RPS15, RPS15A, RPS16, RPS17, RPS18, RPS19, RPS19BP1, RPS2, RPS20, RPS21, RPS23, RPS24, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, RPS3, RPS3A, RPS4X, RPS4Y1, RPS5, RPS6, RPS6KA1, RPS6KA2, RPS6KA3, RPS6KA4, RPS6KA6, RPS6KB1, RPS7, RPS8, RPS9, RPSA, RPTN, RPTOR, RRAD, RRAGA, RRAGB, RRAGC, RRAGD, RRM1, RRM2, RRM2B, RRP1, RRP12, RRP1B, RRP8, RSPH1, RSU1, RTCB, RTKN, RTRAF, RUBCN, RUFY1, RUFY3, RUNX2, RUNX3, RUSC1, RUSC2, RUVBL1, RUVBL2, RWDD1, RXRA, RXRB, S100A1, S100A12, S100A13, S100A16, S100A3, S100A4, S100A6, S100A7, S100A7A, S100A8, S100A9, S100B, S100PBP, SAG, SAMD4A, SAMD4B, SAMD8, SAMD9, SAMSN1, SAP18, SAPCD2, SAR1A, SAR1B, SARM1, SARS1, SART1, SASH1, SAT1, SAV1, SBDS, SBF1, SBF2, SCAP, SCAPER, SCFD1, SCG2, SCGN, SCHIP1, SCLT1, SCLY, SCNN1A, SCOC, SCP2, SCP2D1, SCPEP1, SCYL1, SCYL3, SDCBP, SDCBP2, SDCCAG8, SDE2, SDHAF2, SDS, SDSL, SEC13, SEC14L1, SEC14L2, SEC16A, SEC16B, SEC23A, SEC23B, SEC23IP, SEC24A, SEC24B, SEC24C, SEC24D, SEC31A, SEC61B, SEC61G, SEH1L, SELENBP1, SEM1, SENP2, SENP6, SENP8, SEPHS2, SEPSECS, SEPTIN4, SEPTIN7, SERBP1, SERF1A, SERF1B, SERF2, SERGEF, SERINC5, SERP1, SERPINB10, SERPINB13, SERPINB3, SERPINB4, SERPINB6, SERPINB8, SERPINB9, SERPINE2, SERTAD2, SESN1, SESN2, SET, SETBP1, SETD4, SETD6, SETDB2, SF1, SFI1, SFMBT2, SFN, SFPQ, SFRP1, SGIP1, SGK1, SGK2, SGK3, SGO1, SGO2, SGSM1, SGSM3, SGTA, SH2B1, SH2B2, SH2B3, SH2D1A, SH2D1B, SH2D2A, SH2D3C, SH2D4A, SH3BGRL, SH3BGRL3, SH3BP1, SH3D19, SH3GL1, SH3GL2, SH3GLB1, SH3GLB2, SH3KBP1, SH3PXD2A, SH3RF1, SHANK1, SHANK2, SHANK3, SHARPIN, SHB, SHC1, SHC2, SHC3, SHFL, SHH, SHMT1, SHOC2, SHPK, SHQ1, SIAH1, SIAH2, SIGLEC6, SIGMAR1, SIKE1, SIPA1, SIRT1, SIRT2, SIRT5, SIX5, SKA1, SKA2, SKA3, SKAP1, SKAP2, SKIC2, SKIC3, SKIC8, SKP1, SKP2, SLA, SLA2, SLAIN2, SLBP, SLC12A3, SLC13A5, SLC16A13, SLC16A7, SLC17A2, SLC17A5, SLC22A16, SLC22A5, SLC22A7, SLC25A17, SLC25A20, SLC26A6, SLC27A2, SLC28A1, SLC2A1, SLC2A10, SLC2A4, SLC34A1, SLC35F6, SLC40A1, SLC44A1, SLC66A2, SLC7A14, SLC7A5, SLFN11, SLFN12, SLK, SLU7, SLX4, SMAD1, SMAD2, SMAD3, SMAD4, SMAD5, SMAD6, SMAD7, SMAD9, SMAP1, SMAP2, SMC1A, SMC1B, SMC2, SMC3, SMC4, SMG1, SMG5, SMG6, SMG7, SMG8, SMG9, SMN1, SMN2, SMO, SMOX, SMS, SMUG1, SMURF1, SMURF2, SMYD2, SMYD3, SNAI1, SNAP25, SNAP29, SNAPC2, SNAPIN, SNCA, SNCAIP, SNCB, SND1, SNF8, SNIP1, SNRNP25, SNRNP40, SNRNP48, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNUPN, SNX1, SNX14, SNX15, SNX17, SNX2, SNX27, SNX3, SNX30, SNX32, SNX33, SNX5, SNX6, SNX8, SNX9, SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS6, SOCS7, SOD1, SORBS1, SORBS3, SORCS2, SORD, SORT1, SOS1, SOS2, SOX2, SOX30, SP3, SP4, SP6, SPAG1, SPAG5, SPAG9, SPART, SPAST, SPATA13, SPATA2, SPATA24, SPATA33, SPATA7, SPATS2, SPATS2L, SPC24, SPC25, SPDL1, SPECC1, SPESP1, SPG11, SPG21, SPHK1, SPHK2, SPIN1, SPIN2A, SPIN2B, SPIN3, SPIN4, SPINK5, SPIRE1, SPIRE2, SPMIP6, SPMIP9, SPR, SPRED1, SPRED2, SPRN, SPRR1A, SPRR1B, SPRR2A, SPRR2B, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, SPRY1, SPRY2, SPRY3, SPRY4, SPSB1, SPSB2, SPSB3, SPSB4, SPTA1, SPTAN1, SPTB, SPTBN1, SPTBN2, SPTBN4, SPTBN5, SQSTM1, SRA1, SRC, SREBF1, SREBF2, SRGAP1, SRGAP2, SRGAP3, SRI, SRM, SRMS, SRP14, SRP19, SRP54, SRP68, SRP72, SRP9, SRPK1, SRPK2, SRR, SRRM1, SRSF10, SRSF2, SRSF5, SRSF8, SRXN1, SS18L1, SSB, SSNA1, SST, SSTR2, SSU72, ST13, STAB2, STAC, STAC2, STAC3, STAG1, STAG2, STAM, STAM2, STAMBP, STAMBPL1, STAP1, STAP2, STARD10, STARD13, STARD3, STARD3NL, STARD4, STARD5, STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6, STAU1, STEAP2, STH, STIL, STING1, STIP1, STK10, STK11, STK16, STK24, STK26, STK3, STK36, STK38, STK38L, STK39, STK4, STK40, STMN1, STMN2, STMN3, STON2, STOX1, STRADA, STRADB, STRAP, STRIP1, STRIP2, STRN, STUB1, STX10, STX16, STX17, STX1A, STX1B, STX4, STX5, STX6, STXBP1, STXBP2, STXBP3, STXBP5, STYX, SUDS3, SUFU, SUGT1, SULT1A1, SULT1A2, SULT1A3, SULT1A4, SULT1B1, SULT1C2, SULT1C4, SULT1E1, SULT2A1, SULT2B1, SULT4A1, SULT6B1, SUMO1, SURF4, SVIL, SWAP70, SYAP1, SYDE2, SYK, SYMPK, SYNC, SYNCRIP, SYNGAP1, SYNJ1, SYNJ2, SYNPO, SYNPO2, SYS1, SYT6, SYT7, SYTL2, TAB1, TAB2, TAB3, TACC1, TACC2, TACC3, TACSTD2, TADA1, TAF1D, TAF4, TAF6, TAGAP, TAGLN2, TALDO1, TANGO2, TANK, TAOK1, TAOK2, TAPT1, TARBP2, TARS1, TASL, TASOR2, TASP1, TAT, TAX1BP1, TAX1BP3, TBATA, TBC1D10A, TBC1D10B, TBC1D10C, TBC1D13, TBC1D14, TBC1D16, TBC1D17, TBC1D2, TBC1D23, TBC1D2B, TBC1D30, TBC1D4, TBC1D5, TBC1D7, TBC1D8B, TBCB, TBCC, TBK1, TBXAS1, TCAP, TCF25, TCF3, TCF7L1, TCHH, TCHP, TCIM, TCL1A, TCOF1, TCP1, TCTN1, TDO2, TDRD3, TDRP, TEAD2, TEC, TELO2, TENT4B, TEP1, TEPSIN, TERT, TES, TESC, TESK1, TESPA1, TEX264, TFAM, TFAP2C, TFCP2, TFDP1, TFE3, TFEB, TFEC, TFG, TGFB1I1, TGFBR2, TGFBR3, TGM1, TGM2, TGS1, TH, THAP11, THAP4, THEM4, THG1L, THOC7, THOP1, THRA, THRSP, THSD1, THTPA, THUMPD3, TIA1, TIAL1, TIAM1, TIAM2, TICAM1, TICRR, TIFA, TIGAR, TIPRL, TIRAP, TJP1, TJP2, TK1, TKFC, TKT, TKTL1, TLE1, TLN1, TMCC1, TMEM134, TMEM214, TMEM216, TMEM266, TMEM87A, TMEM87B, TMEM88, TMF1, TMIGD1, TMOD1, TMSB4X, TMT1A, TMT1B, TNFAIP1, TNFAIP3, TNFAIP8L3, TNFRSF10A, TNFRSF11A, TNFRSF25, TNFSF13, TNIK, TNIP1, TNIP2, TNIP3, TNK2, TNKS, TNKS1BP1, TNKS2, TNNC1, TNNC2, TNNI1, TNNI2, TNNI3, TNNT1, TNNT2, TNNT3, TNPO1, TNRC18, TNRC6A, TNRC6B, TNRC6C, TNS3, TNS4, TOB2, TOLLIP, TOM1, TOM1L1, TOMM34, TOMM40, TOP2B, TOPAZ1, TOR1A, TOX3, TP53, TP53BP2, TP53I3, TP53INP1, TP53INP2, TP53RK, TP73, TPCN2, TPH1, TPH2, TPI1, TPK1, TPM1, TPM2, TPM3, TPM4, TPMT, TPP1, TPP2, TPPP, TPPP2, TPRKB, TPT1, TPTE, TPTE2, TPX2, TRADD, TRAF1, TRAF2, TRAF3, TRAF4, TRAF5, TRAF6, TRAK1, TRAK2, TRAM1, TRAPPC1, TRAPPC10, TRAPPC11, TRAPPC12, TRAPPC13, TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC6A, TRAPPC6B, TRAPPC8, TRAPPC9, TRDN, TREML1, TRERF1, TREX1, TRIB1, TRIB3, TRIM11, TRIM16, TRIM17, TRIM21, TRIM22, TRIM24, TRIM25, TRIM26, TRIM27, TRIM31, TRIM32, TRIM34, TRIM36, TRIM37, TRIM38, TRIM39, TRIM39-RPP21, TRIM4, TRIM45, TRIM47, TRIM48, TRIM5, TRIM50, TRIM52, TRIM56, TRIM58, TRIM6, TRIM60, TRIM61, TRIM62, TRIM65, TRIM68, TRIM69, TRIM73, TRIM74, TRIM75, TRIM8, TRIO, TRIP10, TRIP12, TRIP4, TRIP6, TRMT10A, TRMT10B, TRMT112, TRMT2A, TRNT1, TRUB1, TSC1, TSC2, TSC22D1, TSC22D3, TSEN2, TSG101, TSN, TSNAX, TSPAN15, TSPO, TSPOAP1, TSR1, TSR3, TSTD1, TTBK1, TTBK2, TTC1, TTC17, TTC3, TTC5, TTC7B, TTC8, TTF2, TTLL10, TTLL11, TTLL12, TTLL13, TTLL3, TTLL4, TTLL5, TTLL6, TTLL7, TTLL8, TTN, TTPA, TUB, TUBA1A, TUBA4A, TUBB, TUBB4A, TUBB4B, TUBD1, TUBG1, TUBG2, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5, TUBGCP6, TULP1, TULP4, TUT1, TUT4, TUT7, TWF1, TXK, TXLNA, TXLNG, TXN, TXNDC17, TXNDC9, TXNIP, TXNL1, TXNL4A, TXNL4B, TXNRD1, TXNRD2, TXNRD3, TYK2, TYMP, TYMS, TYSND1, UACA, UAP1, UBA1, UBA3, UBA5, UBA52, UBA6, UBA7, UBAC1, UBAP1, UBASH3A, UBB, UBC, UBD, UBE2A, UBE2C, UBE2D1, UBE2D2, UBE2D3, UBE2E1, UBE2E3, UBE2F, UBE2G1, UBE2G2, UBE2H, UBE2I, UBE2J2, UBE2K, UBE2L3, UBE2L6, UBE2M, UBE2N, UBE2O, UBE2Q1, UBE2Q2, UBE2R2, UBE2S, UBE2V1, UBE2Z, UBE3A, UBE3D, UBL4A, UBL7, UBP1, UBQLN1, UBQLN2, UBQLN3, UBQLN4, UBQLNL, UBR1, UBR2, UBR4, UBR5, UBXN1, UBXN11, UBXN2A, UBXN2B, UBXN4, UBXN6, UBXN7, UCHL1, UCHL3, UCHL5, UCK1, UCK2, UCKL1, UFD1, UFL1, UFSP1, UGDH, UGP2, ULBP1, ULK1, ULK2, ULK3, UMPS, UNC119, UNC119B, UNC13B, UNC13D, UNC45A, UNC45B, UNKL, UPB1, UPF1, UPF2, UPF3A, UPF3B, UPP1, UPP2, UQCC3, URGCP, URI1, URM1, UROC1, UROD, UROS, USH1C, USH1G, USO1, USP1, USP10, USP11, USP12, USP13, USP14, USP15, USP17L1, USP17L10, USP17L11, USP17L12, USP17L13, USP17L15, USP17L17, USP17L18, USP17L19, USP17L2, USP17L20, USP17L21, USP17L22, USP17L24, USP17L3, USP17L30, USP17L4, USP17L5, USP17L6P, USP17L7, USP17L8, USP18, USP19, USP20, USP21, USP24, USP25, USP26, USP27X, USP28, USP29, USP30, USP31, USP32, USP33, USP34, USP35, USP36, USP37, USP38, USP4, USP40, USP42, USP45, USP46, USP47, USP48, USP5, USP50, USP6NL, USP7, USP8, USP9X, USP9Y, UTP14A, UTP14C, VAC14, VAMP1, VAMP2, VAMP3, VAMP8, VAPA, VARS1, VARS2, VASH2, VASP, VAV1, VAV2, VAV3, VBP1, VCL, VCP, VCPKMT, VDR, VEZT, VHL, VIM, VIRMA, VPS13A, VPS13C, VPS25, VPS26A, VPS26B, VPS28, VPS29, VPS33B, VPS35, VPS36, VPS37A, VPS41, VPS4A, VPS4B, VPS50, VPS51, VPS52, VPS53, VPS54, VPS9D1, VRK1, VSNL1, VTA1, VTI1A, VTI1B, VWA3B, WAPL, WARS1, WAS, WASF1, WASF2, WASH2P, WASH3P, WASH4P, WASH6P, WASHC1, WASHC2A, WASHC2C, WASHC5, WASL, WBP11, WBP2, WDFY1, WDFY3, WDR1, WDR11, WDR24, WDR26, WDR4, WDR44, WDR45, WDR45B, WDR48, WDR59, WDR6, WDR62, WDR73, WDR77, WDR81, WDR91, WDTC1, WEE2, WHAMM, WIPF1, WIPF2, WIPF3, WIPI1, WIPI2, WLS, WNK1, WNK2, WNK4, WRAP53, WSB1, WSB2, WT1, WWC1, WWC2, WWC3, WWOX, WWP1, WWP2, WWTR1, XAF1, XBP1, XDH, XIAP, XPC, XPNPEP1, XPNPEP3, XPO1, XPO4, XPO5, XPO6, XPOT, XRCC3, XRCC4, XRCC5, XRCC6, XRN1, XYLB, YAF2, YAP1, YARS1, YARS2, YBX1, YBX3, YES1, YKT6, YOD1, YTHDF2, YTHDF3, YWHAB, YWHAE, YWHAG, YWHAH, YWHAQ, YWHAZ, ZAP70, ZBED3, ZBP1, ZBTB14, ZBTB16, ZBTB21, ZBTB33, ZBTB4, ZBTB49, ZC3H15, ZC3H4, ZC3HAV1, ZC3HAV1L, ZCCHC7, ZCRB1, ZDHHC8, ZDHHC9, ZEB1, ZEB2, ZFAND6, ZFAT, ZFP36, ZFP36L1, ZFYVE16, ZFYVE27, ZFYVE28, ZFYVE9, ZHX2, ZMIZ1, ZMYM2, ZNF106, ZNF146, ZNF175, ZNF232, ZNF260, ZNF268, ZNF318, ZNF322, ZNF34, ZNF354A, ZNF385A, ZNF395, ZNF397, ZNF436, ZNF438, ZNF474, ZNF480, ZNF540, ZNF598, ZNF622, ZNF641, ZNF687, ZNF746, ZNRF1, ZNRF2, ZRANB1, ZSCAN26, ZSWIM8, ZUP1, ZW10, ZWILCH, ZWINT, ZYX
ParishinB
Parishin B is a glycoside. Parishin B is a natural product found in Artemisia absinthium with data available. Parishin B, a parishin derivative isolated from Gastrodia elata, may have antioxidant property[1]. Parishin B, a parishin derivative isolated from Gastrodia elata, may have antioxidant property[1].
Hemigossypol
Hemigossypol is a sesquiterpenoid. Hemigossypol is a natural product found in Sida rhombifolia, Hibiscus trionum, and other organisms with data available.
Corypalmine
(+/-)-Corypalmine is a natural product found in Corydalis heterocarpa var. japonica, Corydalis turtschaninovii, and other organisms with data available. Corypalmine is an alkaloid from Stephania cepharantha. Corypalmine is an antifungal. Corypalmine is an alkaloid from Stephania cepharantha. Corypalmine is an antifungal.
Melilotoside
Melilotoside, also known as trans-beta-D-glucosyl-2-hydroxycinnamic acid or beta-D-glucosyl-2-coumarate, belongs to the class of organic compounds known as phenolic glycosides. These are organic compounds containing a phenolic structure attached to a glycosyl moiety. Some examples of phenolic structures include lignans and flavonoids. Melilotoside is an extremely weak basic (essentially neutral) compound (based on its pKa). Melilotoside is found in herbs and spices. Melilotoside has been isolated from Melilotus alba (white melilot), Melilotus altissimus (tall yellow sweet clover), and other plants. Trans-beta-D-glucosyl-2-hydroxycinnamic acid is a glucosyl hydroxycinnamic acid. It is a conjugate acid of a trans-beta-D-glucosyl-2-hydroxycinnamate. Melilotoside is a natural product found in Mikania laevigata, Serpocaulon triseriale, and other organisms with data available.
6-Deoxyjacareubin
6-Deoxyjacareubin is a member of pyranoxanthones. 6-Deoxyjacareubin is a natural product found in Mourera fluviatilis, Hypericum brasiliense, and other organisms with data available.
Fargesone A
Fargesone A is a member of benzodioxoles. Fargesone A is a natural product found in Piper wightii, Piper hymenophyllum, and other organisms with data available.
Eucommiol
Eucommiol is an alicyclic compound that is cyclopent-3-en-1-ol carrying additional hydroxymethyl substituents at positions 3 and 4 as well as a 2-hydroxyethyl substituent at position 2 (the 1R,2R-diastereomer). It has a role as a sedative and a plant metabolite. It is a tetrol, a primary allylic alcohol and an alicyclic compound. Eucommiol is a natural product found in Aucuba japonica, Vitex trifolia, and other organisms with data available. An alicyclic compound that is cyclopent-3-en-1-ol carrying additional hydroxymethyl substituents at positions 3 and 4 as well as a 2-hydroxyethyl substituent at position 2 (the 1R,2R-diastereomer).
3-Isopropylmalic acid
3-Isopropylmalic acid (CAS: 16048-89-8) is an intermediate in valine, leucine, and isoleucine biosynthesis. It is a substrate for 3-isopropylmalate dehydrogenase (TT_C0867) and can be generated from the reduction of 2-isopropyl-3-oxosuccinate. Leucine biosynthesis involves a five-step conversion process starting with the valine precursor 2-keto-isovalerate. The final step in this pathway is catalyzed by two transaminases of broad specificity: branched-chain amino acid transferase (IlvE) and tyrosine aminotransferase (TyrB). This pathway is part of the super pathway of leucine, valine, and isoleucine biosynthesis that generates not only isoleucine and valine but also leucine.
4-Sulfophenol
4-Hydroxybenzenesulfonic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=98-67-9 (retrieved 2024-08-06) (CAS RN: 98-67-9). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
RESORCINOL MONOACETATE
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent Same as: D02393
2-Naphthalenesulfonic acid
CONFIDENCE standard compound; INTERNAL_ID 1273; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3266; ORIGINAL_PRECURSOR_SCAN_NO 3264 CONFIDENCE standard compound; INTERNAL_ID 1273; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3270; ORIGINAL_PRECURSOR_SCAN_NO 3268 CONFIDENCE standard compound; INTERNAL_ID 1273; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3298; ORIGINAL_PRECURSOR_SCAN_NO 3294 CONFIDENCE standard compound; INTERNAL_ID 1273; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3290; ORIGINAL_PRECURSOR_SCAN_NO 3285 CONFIDENCE standard compound; INTERNAL_ID 1273; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3285; ORIGINAL_PRECURSOR_SCAN_NO 3282 CONFIDENCE standard compound; INTERNAL_ID 1273; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3292; ORIGINAL_PRECURSOR_SCAN_NO 3289 CONFIDENCE standard compound; INTERNAL_ID 626; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3356; ORIGINAL_PRECURSOR_SCAN_NO 3352 CONFIDENCE standard compound; INTERNAL_ID 626; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3363; ORIGINAL_PRECURSOR_SCAN_NO 3361 CONFIDENCE standard compound; INTERNAL_ID 626; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3353; ORIGINAL_PRECURSOR_SCAN_NO 3350 CONFIDENCE standard compound; INTERNAL_ID 626; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3351; ORIGINAL_PRECURSOR_SCAN_NO 3348 CONFIDENCE standard compound; INTERNAL_ID 626; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3344; ORIGINAL_PRECURSOR_SCAN_NO 3341 CONFIDENCE standard compound; INTERNAL_ID 626; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3371; ORIGINAL_PRECURSOR_SCAN_NO 3368 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 8811 CONFIDENCE standard compound; EAWAG_UCHEM_ID 653 CONFIDENCE standard compound; INTERNAL_ID 2300
2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine
2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine, also known as EDDP, is a major inactive metabolite of the opioid methadone. Methadone is an opioid drug that is often used to treat addiction to other opioids, such as heroin, oxycodone or fentanyl. Methadone is metabolised in the liver and small intestine where it is converted to EDDP through N-demethylation and cyclization by CYP3A4 (PMID: 15501692, 27320437). EDDP and methadone are eliminated through the kidneys. As such it is common to monitor the urine of patients in a clinical and forensic settings. EDDP is formed through N-desmethylmethadone reacting with itself and cyclizing through condensation of the secondary amine with the carbonyl group (PMID: 27320437). EDDP belongs to the family of compounds known as Diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups. EDDP is only found in individuals who have taken or been given methadone. CONFIDENCE standard compound; EAWAG_UCHEM_ID 2825
Chloramben
CONFIDENCE standard compound; INTERNAL_ID 246; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3455; ORIGINAL_PRECURSOR_SCAN_NO 3453 CONFIDENCE standard compound; INTERNAL_ID 246; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3520; ORIGINAL_PRECURSOR_SCAN_NO 3516
2-(1-Naphthyl)acetamide
Plant growth regulator. Plant growth regulator
Carbinoxamine
Carbinoxamine, also known as carbinoxamine maleate or clistin, is a member of the class of compounds known as benzylethers. Benzylethers are aromatic ethers with the general formula ROCR (R = alkyl, aryl; R=benzene). Carbinoxamine is practically insoluble (in water) and a very strong basic compound (based on its pKa). Carbinoxamine can be found in barley and garden onion, which makes carbinoxamine a potential biomarker for the consumption of these food products. Carbinoxamine can be found primarily in blood and urine. In humans, carbinoxamine is involved in the carbinoxamine h1-antihistamine action. Carbinoxamine is a non-carcinogenic (not listed by IARC) potentially toxic compound. Carbinoxamine is a drug which is used for symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis, as well as allergic conjunctivitis caused by foods and inhaled allergens. also for the relief of allergic reactions to blood or plasma, and the symptomatic management of mild, uncomplicated allergic skin manifestations of urticaria and angioedema. Carbinoxamine (Clistin, Palgic, Rondec, Rhinopront) is a antihistamine and anticholinergic agent. It was first launched in the United States by the McNeil Corporation under the brand name Clistin. It is now available under the brand name Palgic as 4 mg tablets or 4 mg/5 mL liquid. It is approved by the U.S. Food and Drug Administration (FDA) (specifically at the 4 mg dose/strength) for hay fever (a.k.a. allergic rhinitis, SAR and PAR); vasomotor rhinitis; mild urticaria; angioedema, dermatographism and allergic conjunctivitis. Carbinoxamine is a histamine antagonist, specifically an H1-antagonist. The maleic acid salt of the levorotatory isomer is sold as the prescription drug rotoxamine . Carbinoxamine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. Carbinoxamines anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown (DrugBank). Carbinoxamine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. Carbinoxamines anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown (T3DB). Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. The product label for carbinoxamine as an over the counter cough and cold medicine is being modified to state do not use in children under 4 years of age in order to prevent and reduce misuse, as many unapproved carbinoxamine-containing preparations contained inappropriate labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and the use in children under 2 years of age), which can potentially cause serious health risks. R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AA - Aminoalkyl ethers D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist
Metosulam
Selective post-emergence herbicide used on cereals against broad-leaved weeds Selective post-emergence herbicide used on cereals against broad-leaved weed
Benzoyl ecgonine
Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver. [Wikipedia] CONFIDENCE standard compound; INTERNAL_ID 1590
Aminocarb
CONFIDENCE standard compound; INTERNAL_ID 666; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3190; ORIGINAL_PRECURSOR_SCAN_NO 3188 CONFIDENCE standard compound; INTERNAL_ID 666; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3698; ORIGINAL_PRECURSOR_SCAN_NO 3696 CONFIDENCE standard compound; INTERNAL_ID 666; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3181; ORIGINAL_PRECURSOR_SCAN_NO 3177 CONFIDENCE standard compound; INTERNAL_ID 666; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3692; ORIGINAL_PRECURSOR_SCAN_NO 3690 CONFIDENCE standard compound; INTERNAL_ID 666; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3193; ORIGINAL_PRECURSOR_SCAN_NO 3192 CONFIDENCE standard compound; INTERNAL_ID 666; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3182; ORIGINAL_PRECURSOR_SCAN_NO 3180 CONFIDENCE standard compound; INTERNAL_ID 666; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3706; ORIGINAL_PRECURSOR_SCAN_NO 3704 CONFIDENCE standard compound; INTERNAL_ID 666; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3178; ORIGINAL_PRECURSOR_SCAN_NO 3176 CONFIDENCE standard compound; INTERNAL_ID 666; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3676; ORIGINAL_PRECURSOR_SCAN_NO 3673 CONFIDENCE standard compound; INTERNAL_ID 666; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3212; ORIGINAL_PRECURSOR_SCAN_NO 3210 CONFIDENCE standard compound; INTERNAL_ID 666; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3701; ORIGINAL_PRECURSOR_SCAN_NO 3699 CONFIDENCE standard compound; INTERNAL_ID 666; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3672; ORIGINAL_PRECURSOR_SCAN_NO 3670 C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor D010575 - Pesticides > D007306 - Insecticides D016573 - Agrochemicals
Testosterone Phenylpropionate
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Fluvastatin
Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reducuase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent C471 - Enzyme Inhibitor > C1655 - HMG-CoA Reductase Inhibitor Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].
Monolinuron
CONFIDENCE standard compound; INTERNAL_ID 955; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8335; ORIGINAL_PRECURSOR_SCAN_NO 8330 CONFIDENCE standard compound; INTERNAL_ID 955; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8309; ORIGINAL_PRECURSOR_SCAN_NO 8304
linustatin
2-Ethyl-5-methyl-3,3-diphenyl-1-pyrroline
2-Ethyl-5-methyl-3,3-diphenyl-1-pyrroline is a metabolite of methadone. Methadone (also known as Symoron, Dolophine, Amidone, Methadose, Physeptone, Heptadon, Phy and many other names) is a synthetic opioid, used medically as an analgesic and a maintenance anti-addictive for use in patients with opioid dependency. It was developed in Germany in 1937. Although chemically unlike morphine or heroin, methadone acts on the same opioid receptors as these drugs, and thus has many of the same effects. (Wikipedia)
3-Acetylmorphine
D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids
Thiethylperazine
A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457) R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AD - Phenothiazine derivatives D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent D005765 - Gastrointestinal Agents > D000932 - Antiemetics D002491 - Central Nervous System Agents Thiethylperazine, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine is also a selective ABCC1activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine has anti-emetic, antipsychotic and antimicrobial effects[1][2][3].
D-Chicoric acid
D-Chicoric acid is found in green vegetables. D-Chicoric acid is isolated from chicory (Cichorium intybus) and Cichorium endivia (endive). Isolated from chicory (Cichorium intybus) and Cichorium endivia (endive). D-Chicoric acid is found in green vegetables. Chicoric acid (Cichoric acid), an orally active dicaffeyltartaric acid, induces reactive oxygen species (ROS) generation. Chicoric acid inhibits cell viability and induces mitochondria-dependent apoptosis in 3T3-L1 preadipocytes through ROS-mediated PI3K/Akt and MAPK signaling pathways. Chicoric acid increases glucose uptake, improves insulin resistance, and attenuates glucosamine-induced inflammation. Chicoric acid has antidiabetic properties and antioxidant, anti-inflammatory effects[1][2][3]. Chicoric acid (Cichoric acid), an orally active dicaffeyltartaric acid, induces reactive oxygen species (ROS) generation. Chicoric acid inhibits cell viability and induces mitochondria-dependent apoptosis in 3T3-L1 preadipocytes through ROS-mediated PI3K/Akt and MAPK signaling pathways. Chicoric acid increases glucose uptake, improves insulin resistance, and attenuates glucosamine-induced inflammation. Chicoric acid has antidiabetic properties and antioxidant, anti-inflammatory effects[1][2][3]. L-Chicoric Acid ((-)-Chicoric acid) is a dicaffeoyltartaric acid and a potent, selective and reversible HIV-1 integrase inhibitor with an IC50 of ~100 nM. L-Chicoric Acid inhibits HIV-1 replication in tissue culture[1][2][3]. L-Chicoric Acid ((-)-Chicoric acid) is a dicaffeoyltartaric acid and a potent, selective and reversible HIV-1 integrase inhibitor with an IC50 of ~100 nM. L-Chicoric Acid inhibits HIV-1 replication in tissue culture[1][2][3].
2-METHYLPYRROLIDINE
A member of the class of pyrrolidines that is pyrrolidine which is substituted by a methyl group at position 2. MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; RGHPCLZJAFCTIK-UHFFFAOYSA-N_STSL_0186_2-Methylpyrrolidine_0500fmol_180831_S2_L02M02_68; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I. MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
benz(a)acridine
CONFIDENCE standard compound; INTERNAL_ID 8030 CONFIDENCE standard compound; INTERNAL_ID 10
Michlers ketone
INTERNAL_ID 250; CONFIDENCE standard compound; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9520; ORIGINAL_PRECURSOR_SCAN_NO 9519 CONFIDENCE standard compound; INTERNAL_ID 250; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9492; ORIGINAL_PRECURSOR_SCAN_NO 9487 CONFIDENCE standard compound; INTERNAL_ID 250; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9500; ORIGINAL_PRECURSOR_SCAN_NO 9498 CONFIDENCE standard compound; INTERNAL_ID 250; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9534; ORIGINAL_PRECURSOR_SCAN_NO 9532 CONFIDENCE standard compound; INTERNAL_ID 250; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9547; ORIGINAL_PRECURSOR_SCAN_NO 9546 CONFIDENCE standard compound; INTERNAL_ID 250; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9470; ORIGINAL_PRECURSOR_SCAN_NO 9468 CONFIDENCE standard compound; INTERNAL_ID 250; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9520; ORIGINAL_PRECURSOR_SCAN_NO 9519 CONFIDENCE standard compound; INTERNAL_ID 2291 CONFIDENCE standard compound; INTERNAL_ID 8123 CONFIDENCE standard compound; INTERNAL_ID 4144
1,2-CYCLOHEXANEDIOL
trans-Cyclohexane-1,2-diol is an endogenous metabolite.
N-[4-[1-[2-(6-Methylpyridin-2-yl)ethyl]piperidine-4-carbonyl]phenyl]methanesulfonamide
D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents
2-(Methylamino)benzoic acid
2-(Methylamino)benzoic acid is found in citrus. 2-(Methylamino)benzoic acid is isolated from grapefruit peel oi KEIO_ID M127 2-(Methylamino)benzoic acid is the main metabolite of methyl-N-methylanthranilates (MMA) (HY-76705) and is the compound in which the ester group is converted. MMA can be isolated from citrus fruits and has potential analgesic activity. 2-(Methylamino)benzoic acid was used to detect the metabolic levels of MMA in rat liver[1].
Ketopantolactone
2-dehydropantolactone is a tetrahydrofurandione. It is functionally related to a pantoic acid. 2-Dehydropantolactone is a metabolite found in or produced by Saccharomyces cerevisiae. Ketopantolactone. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=13031-04-4 (retrieved 2024-10-30) (CAS RN: 13031-04-4). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
18R-hydroxy-5Z,8Z,11Z,14Z,16E-eicosapentaenoic acid
18R-hydroxy-5Z,8Z,11Z,14Z,16E-eicosapentaenoic acid is also known as 18-HEPE or 18(R)-Hydroxyeicosa-5Z,8Z,11E,14Z,16E-pentaenoate. 18R-hydroxy-5Z,8Z,11Z,14Z,16E-eicosapentaenoic acid is considered to be practically insoluble (in water) and acidic. 18R-hydroxy-5Z,8Z,11Z,14Z,16E-eicosapentaenoic acid is an eicosanoid lipid molecule
xi-gamma-Undecalactone
(±)-5-Heptyldihydro-2(3H)-furanone is a flavouring ingredient. [Raw Data] CB092_gamma-Undecalactone_pos_20eV_CB000039.txt [Raw Data] CB092_gamma-Undecalactone_pos_30eV_CB000039.txt [Raw Data] CB092_gamma-Undecalactone_pos_10eV_CB000039.txt
Cytidine 3'-monophosphate
Cytidine 3-monophosphate (3-CMP), also known as 3-cytidylic acid or 3-cytidylate, belongs to the class of organic compounds known as pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups. Cytidine 3-monophosphate has been identified in the human placenta (PMID: 32033212). Acquisition and generation of the data is financially supported in part by CREST/JST.
1-(2,6-Dihydroxy-4-methoxyphenyl)-3-phenyl-1-propanone
1-(2,6-Dihydroxy-4-methoxyphenyl)-3-phenyl-1-propanone is isolated from Populus balsamifera (balsam poplar) oi Isolated from Populus balsamifera (balsam poplar) oil.
trans-cinnamoyl-beta-D-glucoside
Trans-cinnamoyl-beta-d-glucoside, also known as 1-O-trans-cinnamoyl-beta-D-glucopyranose, is a member of the class of compounds known as O-cinnamoyl glycosides. O-cinnamoyl glycosides are o-glycoside derivatives of cinnamic acid. Cinnamic acid is an aromatic compound containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid. Trans-cinnamoyl-beta-d-glucoside is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Trans-cinnamoyl-beta-d-glucoside can be found in a number of food items such as angelica, cherry tomato, garden cress, and yam, which makes trans-cinnamoyl-beta-d-glucoside a potential biomarker for the consumption of these food products. Trans-cinnamoyl-β-d-glucoside, also known as 1-O-trans-cinnamoyl-beta-D-glucopyranose, is a member of the class of compounds known as O-cinnamoyl glycosides. O-cinnamoyl glycosides are o-glycoside derivatives of cinnamic acid. Cinnamic acid is an aromatic compound containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid. Trans-cinnamoyl-β-d-glucoside is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Trans-cinnamoyl-β-d-glucoside can be found in a number of food items such as angelica, cherry tomato, garden cress, and yam, which makes trans-cinnamoyl-β-d-glucoside a potential biomarker for the consumption of these food products.
Antiarol
3,4,5-trimethoxyphenol is a member of the class of phenols that is phenol substituted by methoxy groups at positions 3, 4 and 5. It has a role as a plant metabolite. It is a member of phenols and a member of methoxybenzenes. 3,4,5-Trimethoxyphenol is a natural product found in Diospyros eriantha, Tarenna attenuata, and other organisms with data available. A member of the class of phenols that is phenol substituted by methoxy groups at positions 3, 4 and 5. Antiarol (3,4,5-Trimethoxyphenol) is a natural compound isolated from Cochlospermum vitifolium. Antiarol (3,4,5-Trimethoxyphenol) is a natural compound isolated from Cochlospermum vitifolium.
3-Hydroxy-N-(2-oxotetrahydrofuran-3-yl)octanamide
Chromafenozide
Leucyl-leucine
Leucylleucine is a dipeptide composed of two leucine residues. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signalling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. Leu-Leu-OH, a Leu derivative, is a dipeptide.
Spheroidenone
The carotenone that is the 2-oxo derivative of (3E)-1-methoxy-3,4-didehydro-1,2,7,8-tetrahydro-psi,psi-carotene. D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
4a-Carbinolamine tetrahydrobiopterin
Carbinolamine 4a-hydroxytetrahydrobiopterin is formed as a consequence of the hydroxylation of phenylalanine to tyrosine. During the physiological reaction tetrahydrobiopterin (the naturally occurring cofactor for phenylalanine hydroxylase), and the two substrates phenylalanine and molecular oxygen combine with phenylalanine hydroxylase to form a quarternary complex. An enzyme, 4a-carbinolamine dehydratase, catalyzes the reaction. (PMID: 2722790) [HMDB] Carbinolamine 4a-hydroxytetrahydrobiopterin is formed as a consequence of the hydroxylation of phenylalanine to tyrosine. During the physiological reaction tetrahydrobiopterin (the naturally occurring cofactor for phenylalanine hydroxylase), and the two substrates phenylalanine and molecular oxygen combine with phenylalanine hydroxylase to form a quarternary complex. An enzyme, 4a-carbinolamine dehydratase, catalyzes the reaction. (PMID: 2722790). COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
oxalyl-CoA
An omega-carboxyacyl-CoA that results from the formal condensation of the thiol group of coenzyme A with one of the carboxy groups of oxalic acid.
Sinapoyl-CoA
The S-sinapoyl derivative of coenzyme A.
5-Formiminotetrahydrofolic acid
5-Formiminotetrahydrofolic acid is a substrate for Formimidoyltransferase-cyclodeaminase. [HMDB] 5-Formiminotetrahydrofolic acid is a substrate for Formimidoyltransferase-cyclodeaminase.
streptidine
An amino cyclitol that is scyllo-inositol in which the hydroxy groups at positions 1 and 3 are replaced by guanidino groups.
2-Acetolactate
2-Acetolactate is involved in the butanoate metabolism and pantothenate and CoA biosynthesis pathways. In the butanoate metabolism pathway, 2-Acetolactate is created from 2-(alpha-Hydroxyethyl)thiamine diphosphate by acetolactate synthase [EC:2.2.1.6]. 2-Acetolactate is then converted to (R)-Acetoin by acetolactate decarboxylase [EC:4.1.1.5]. In the pantothenate and CoA pathway, 2-Acetolactate is irreversibly created from pyruvate by acetolactate synthase [EC:2.2.1.6]. 2-Acetolactate is then irreversibly converted to 2,3-Dihydroxy-3-methylbutanoate by ketol-acid reductoisomerase [EC:1.1.1.86]. 2-Acetolactate is involved in the butanoate metabolism and pantothenate and CoA biosynthesis pathways.
Formylmethanofuran
UDP-D-apiose
D-apiose is a plant-specific branched-chain monosaccharide found in rhamnogalacturonan II (RG-II), apiogalacturonan, and several apioglycosides. Within RG-II, d-apiose serves as the binding site for borate, which leads to the formation of cross-links within the wall. Biochemical studies in duckweed and parsley have established that uridine 5-diphospho-d-apiose (UDP-d-apiose) is formed from UDP-d-glucuronate by decarboxylation and re-arrangement of the carbon skeleton, leading to ring contraction and branch formation. The enzyme catalyzing this reaction also forms UDP-d-xylose by decarboxylation of UDP-d-glucuronate, and has therefore been named UDP-d-apiose/UDP-d-xylose synthase. (PMID: 12969423) [HMDB] D-Apiose is a plant-specific branched-chain monosaccharide found in rhamnogalacturonan II (RG-II), apiogalacturonan, and several apioglycosides. Within RG-II, D-apiose serves as the binding site for borate, which leads to the formation of cross-links within the wall. Biochemical studies in duckweed and parsley have established that uridine 5-diphospho-D-apiose (UDP-D-apiose) is formed from UDP-D-glucuronate by decarboxylation and re-arrangement of the carbon skeleton, leading to ring contraction and branch formation. The enzyme catalyzing this reaction also forms UDP-D-xylose by decarboxylation of UDP-D-glucuronate, and has therefore been named UDP-D-apiose/UDP-D-xylose synthase (PMID: 12969423).
Rifamycin O
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D012294 - Rifamycins
(+)-Sabinone
(+)-sabinone is a member of the class of compounds known as bicyclic monoterpenoids. Bicyclic monoterpenoids are monoterpenoids containing exactly 2 rings, which are fused to each other. Thus, (+)-sabinone is considered to be an isoprenoid lipid molecule (+)-sabinone is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). (+)-sabinone can be found in common sage, which makes (+)-sabinone a potential biomarker for the consumption of this food product.
Gentamicin A
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D005839 - Gentamicins
Aspulvinone E
A 4-hydroxy-5-(4-hydroxybenzylidene)-3-(4-hydroxyphenyl)furan-2(5H)-one in which the double bond adopts a Z-configuration. It is a marine metabolite isolated from the fungus Aspergillus terreus and exhibits antiviral activity.
Prostanoic acid
A carbocyclic fatty acid composed of heptanoic acid having a (1S,2S)-2-octylcyclopentyl substituent at position 7.
cis-Sabinol
(+)-cis-Sabinol belongs to the class of organic compounds known as bicyclic monoterpenoids. These are monoterpenoids containing exactly 2 rings, which are fused to each other. Thus, (+)-cis-sabinol is an isoprenoid lipid molecule. Monoterpenoids are terpenes that contain 10 carbon atoms and are comprised of two isoprene units. The biosynthesis of monoterpenes is known to occur mainly through the methyl-eritritol-phosphate (MEP) pathway in the plastids (PMID: 23746261). Geranyl diphosphate (GPP) is a key intermediate in the biosynthesis of cyclic monoterpenes. GPP undergoes several cyclization reactions to yield a diverse number of cyclic arrangements. (+)-cis-Sabinol is very hydrophobic, practically insoluble in water, and relatively neutral. Artemisia annuaand (https://doi.org/10.1007/s11418-006-0112-9) and in herbal plant Dendranthema indicum (PMID: 29510531). (+)-cis-sabinol, also known as sabinol or sabinol, (1alpha,3alpha,5alpha)-isomer, is a member of the class of compounds known as bicyclic monoterpenoids. Bicyclic monoterpenoids are monoterpenoids containing exactly 2 rings, which are fused to each other. Thus, (+)-cis-sabinol is considered to be an isoprenoid lipid molecule (+)-cis-sabinol is slightly soluble (in water) and an extremely weak acidic compound (based on its pKa). (+)-cis-sabinol can be found in peppermint, which makes (+)-cis-sabinol a potential biomarker for the consumption of this food product.
Uridine 2',3'-cyclic phosphate
Uridine 2,3-cyclic phosphate is a cyclic nucleotide. A cyclic nucleotide is any nucleotide in which the phosphate group is bonded to two of the sugars hydroxyl groups, forming a cyclical or ring structure. Cyclic phosphates are commonly found at the 3 end of mRNAs and other small RNAs. Uridine 2,3-cyclic phosphate is a substrate for the enzyme 2,3-cyclic nucleotide-3-phosphodiesterase (CNPase, EC 3.1.4.37) which hydrolyses it to Uridine 2-phosphate. CNPase is a unique RNase in that it only cleaves nucleoside 2,3-cyclic phosphates and not the RNA internucleotide linkage, like other RNases such as RNase A and RNase T1. [HMDB] Uridine 2,3-cyclic phosphate is a cyclic nucleotide. A cyclic nucleotide is any nucleotide in which the phosphate group is bonded to two of the sugars hydroxyl groups, forming a cyclical or ring structure. Cyclic phosphates are commonly found at the 3 end of mRNAs and other small RNAs. Uridine 2,3-cyclic phosphate is a substrate for the enzyme 2,3-cyclic nucleotide-3-phosphodiesterase (CNPase, EC 3.1.4.37) which hydrolyses it to Uridine 2-phosphate. CNPase is a unique RNase in that it only cleaves nucleoside 2,3-cyclic phosphates and not the RNA internucleotide linkage, like other RNases such as RNase A and RNase T1.
2-Oxosuccinamate
This compound belongs to the family of Short-chain Keto Acids and Derivatives. These are keto acids with an alkyl chain the contains less than 6 carbon atoms
(2E)-Pentenoyl-CoA
(2E)-Pentenoyl-CoA is also known as (2E)-Pent-2-enoyl-coenzyme A(4-). (2E)-Pentenoyl-CoA is considered to be slightly soluble (in water) and acidic
4-Hydroxy-3-methoxy-cinnamoylglycine
4-Hydroxy-3-methoxy-cinnamoylglycine belongs to the family of Acyl Glycines. These are organic compounds containing a glycine residue with the N-atom attached to another moiety through an N-ester bond
Acetylblasticidin S
A member of the class of blasticidins that is blasticidin S in which the side-chain amino group is acetylated.
Cortisol 21-sulfate
Cortisol 21-sulfate is also known as Cortisol-21-sulfuric acid or 4-Pregnen-11,17,21-triol-3,20-dione 21-sulfate. Cortisol 21-sulfate is considered to be practically insoluble (in water) and acidic. Cortisol 21-sulfate is a steroid conjugate lipid molecule D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
N-Hydroxy-L-tyrosine
Biosynthetic intermediate of dhurrin in Sorghum bicolor (sorghum). N-Hydroxy-L-tyrosine is found in many foods, some of which are allspice, asparagus, lemon thyme, and sparkleberry. N-Hydroxy-L-tyrosine is found in cereals and cereal products. Biosynthetic intermediate of dhurrin in Sorghum bicolor (sorghum).
Gamma-linolenoyl-CoA
Gamma-linolenoyl-CoA is the product of a chemical reaction that involves linoleoyl-CoA desaturase which acts as a catalyst. In enzymology, linoleoyl-CoA desaturase (EC 1.14.19.3) is an enzyme that catalyzes the chemical reaction. linoleoyl-CoA + AH2 + O2 gamma-linolenoyl-CoA + A + 2 H2O. The 3 substrates of this enzyme are linoleoyl-CoA, AH2, and O2, whereas its 3 products are gamma-linolenoyl-CoA, A, and H2O. (Wikipedia). gamma-Linolenoyl-CoA is the product of a chemical reaction that involves linoleoyl-CoA desaturase which acts as a catalyst. In enzymology, linoleoyl-CoA desaturase (EC 1.14.19.3) is an enzyme that catalyzes the chemical reaction
9-O-Acetylneuraminic acid
The acetate ester of the primary hydroxy group of neuraminic acid.
8Z,11Z,14Z-eicosatrienoyl-CoA
8Z,11Z,14Z-eicosatrienoyl-CoA participates in the biosynthesis of unsaturated fatty acids. 8Z,11Z,14Z-eicosatrienoyl-CoA is converted from (8Z,11Z,14Z)-Icosatrienoic acid via palmitoyl-CoA hydrolase [EC:3.1.2.2].
Unsaturated fatty acids are of similar form, except that one or more alkenyl functional groups exist along the chain, with each alkene substituting a single-bonded "-CH2-CH2-" part of the chain with a double-bonded "-CH=CH-" portion (that is, a carbon double-bonded to another carbon). The differences in geometry between the various types of unsaturated fatty acids, as well as between saturated and unsaturated fatty acids, play an important role in biological processes, and in the construction of biological structures (such as cell membranes). (Wikipedia)
.8Z,11Z,14Z-eicosatrienoyl-CoA participates in the biosynthesis of unsaturated fatty acids. 8Z,11Z,14Z-eicosatrienoyl-CoA is converted from (8Z,11Z,14Z)-Icosatrienoic acid via palmitoyl-CoA hydrolase [EC:3.1.2.2].
D-Erythrulose 4-phosphate
A ketotetrose phosphate that is D-erythrulose carrying a phosphono substituent at position O-4.
4-Amino-3-hydroxybutyrate
4-Amino-3-hydroxybutyrate belongs to the class of organic compounds known as hydroxy fatty acids. These are fatty acids in which the chain bears a hydroxyl group.
CMP-N-glycoloylneuraminate
CMP-N-glycoloylneuraminate is an intermediate in Aminosugars metabolism. It is generated from CMP-N-acetylneuraminate via the enzyme CMP-N-acetylneuraminate monooxygenase (EC 1.14.18.2). CMP-N-glycoloylneuraminate can be converted to N-Glycolylneuraminate via the enzyme N-acylneuraminate cytidylyltransferase (EC 2.7.7.43). [HMDB] CMP-N-glycoloylneuraminate is an intermediate in Aminosugars metabolism. It is generated from CMP-N-acetylneuraminate via the enzyme CMP-N-acetylneuraminate monooxygenase (EC 1.14.18.2). CMP-N-glycoloylneuraminate can be converted to N-Glycolylneuraminate via the enzyme N-acylneuraminate cytidylyltransferase (EC 2.7.7.43).
(Z)-But-1-ene-1,2,4-tricarboxylate
This compound belongs to the family of Tricarboxylic Acids and Derivatives. These are organic compounds containing three carboxylic acid groups (or salt/ester derivatives thereof).
UDP-4-dehydro-6-deoxy-D-glucose
UDP-4-dehydro-6-deoxy-D-glucose, also known as UDP-4-keto-6-deoxy-D-glucose, belongs to the class of organic compounds known as pyrimidine nucleotide sugars. These are pyrimidine nucleotides bound to a saccharide derivative through the terminal phosphate group. UDP-4-dehydro-6-deoxy-D-glucose is an extremely weak basic (essentially neutral) compound (based on its pKa). Outside of the human body, UDP-4-dehydro-6-deoxy-D-glucose has been detected, but not quantified in, several different foods, such as Oregon yampahs, oriental wheat, Chinese mustards, blackcurrants, and pomegranates. This could make UDP-4-dehydro-6-deoxy-D-glucose a potential biomarker for the consumption of these foods. UDP-4-dehydro-6-deoxy-D-glucose is synthesized from UDP-glucose via the enzyme UDP-glucose 4,6-dehydratase. UDP-4-dehydro-6-deoxy-D-glucose is synthesized from UDP-glucose through the enzyme UDP-glucose 4,6-dehydratase. [HMDB]. UDP-4-dehydro-6-deoxy-D-glucose is found in many foods, some of which are alaska wild rhubarb, soy bean, ginkgo nuts, and common beet.
SCHEMBL4290912
D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids
BENZOYLARGININE NITROANILIDE
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D002863 - Chromogenic Compounds D004396 - Coloring Agents
3alpha,7alpha-Dihydroxycoprostanic acid
3α,7α-Dihydroxycoprostanic acid is a bile acid excreted in small amounts in the urine of healthy subjects (PMID: 864325). 3α,7α-Dihydroxycoprostanic acid is the precursor to chenodeoxycholic acid, a bile acid. Bile acids are steroid acids found predominantly in the bile of mammals. The distinction between different bile acids is minute, depending only on the presence or absence of hydroxyl groups on positions 3, 7, and 12. Bile acids are physiological detergents that facilitate excretion, absorption, and transport of fats and sterols in the intestine and liver. Bile acids are also steroidal amphipathic molecules derived from the catabolism of cholesterol. They modulate bile flow and lipid secretion, are essential for the absorption of dietary fats and vitamins, and have been implicated in the regulation of all the key enzymes involved in cholesterol homeostasis. Bile acids recirculate through the liver, bile ducts, small intestine, and portal vein to form an enterohepatic circuit. They exist as anions at physiological pH, and consequently require a carrier for transport across the membranes of the enterohepatic tissues. The unique detergent properties of bile acids are essential for the digestion and intestinal absorption of hydrophobic nutrients. Bile acids have potent toxic properties (e.g. membrane disruption) and there are a plethora of mechanisms to limit their accumulation in blood and tissues. 3a,7a-Dihydroxycoprostanic acid is a bile acid excreted in small amounts in the urine of healthy subjects (PMID 864325)
9S-hydroxy-11,15-dioxo-5Z,13E-prostadienoic acid
9S-hydroxy-11,15-dioxo-5Z,13E-prostadienoic acid is also known as 15-Deoxy-15-oxo-prostaglandin D2. 9S-hydroxy-11,15-dioxo-5Z,13E-prostadienoic acid is considered to be practically insoluble (in water) and acidic. 9S-hydroxy-11,15-dioxo-5Z,13E-prostadienoic acid is an eicosanoid lipid molecule
Histidylleucine
Histidylleucine is a dipeptide composed of histidine and leucine. It is an incomplete breakdown product of protein digestion or protein catabolism. Dipeptides are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. Some dipeptides are known to have physiological or cell-signalling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.
3-Oxodecanoyl-CoA
3-oxodecanoyl-coa, also known as 3-ketodecanoyl-CoA is an acyl-CoA or acyl-coenzyme A. More specifically, it is a 3-oxodecanoic acid thioester of coenzyme A. 3-oxodecanoyl-coa is an acyl-CoA with 10 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. 3-oxodecanoyl-coa is therefore classified as a medium chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. 3-oxodecanoyl-coa, being a medium chain acyl-CoA is a substrate for medium chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, 3-Oxodecanoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of 3-Oxodecanoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts 3-Oxodecanoyl-CoA into 3-oxodecanoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, 3-oxodecanoylcarnitine is converted back to 3-Oxodecanoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of 3-Oxodecanoyl-CoA occurs in four steps. First, since 3-Oxodecanoyl-CoA is a medium chain acyl-CoA it is the substrate for a medium chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of 3-Oxodecanoyl-CoA, creating a double bond between the alpha and beta carbons. FAD is the hydrogen acceptor, yielding FADH2. Second, Enoyl-CoA hydrase catalyzes the addition of water across the newly formed double bond to make an alcohol. Third, 3-hydroxyacyl-CoA dehydrogenase oxidizes the alcohol group to a ketone and NADH is ... 3-Oxodecanoyl-CoA is an intermediate in fatty acid metabolism, the substrate of the enzyme acetyl-Coenzyme A acetyltransferase 1 and 2 [EC:2.3.1.16-2.3.1.9]; 3-Oxodecanoyl-CoA is an intermediate in fatty acid elongation in mitochondria, being the substrate of the enzymes beta-hydroxyacyl-CoA dehydrogenase and 3-hydroxyacyl-CoA dehydrogenase [EC 1.1.1.211-1.1.1.35]. (KEGG) [HMDB]. 3-Oxodecanoyl-CoA is found in many foods, some of which are chinese cabbage, calabash, safflower, and sunburst squash (pattypan squash).
3-Oxooctanoyl-CoA
3-Oxooctanoyl-CoA is the substrate of the acetyl-CoA C-acyltransferase/oxoacyl-CoA thiolase A (EC 2.3.1.16, SCP2/3-oxoacyl-CoA thiolase) present in peroxisomes from normal liver. Peroxisomes beta -oxidize a wide variety of substrates including straight chain fatty acids, 2-methyl-branched fatty acids, and the side chain of the bile acid intermediates di- and trihydroxycoprostanic acids. Peroxisomes contain several beta -oxidation pathways with different substrate specificities; or example, straight chain acyl-CoAs are desaturated by palmitoyl-CoA oxidase, and their enoyl-CoAs are then converted to 3-oxoacyl-CoAs by MFP-1, which forms (hydration) and dehydrogenates L-3(3S)-hydroxyacyl-CoAs; for example, straight chain acyl-CoAs are desaturated by palmitoyl-CoA oxidase (23), and their enoyl-CoAs are then converted to 3-oxoacyl-CoAs by 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35), which forms (hydration) and dehydrogenates L-3(3S)-hydroxyacyl-CoAs and their enoyl-CoAs are then converted to the corresponding 3-oxoacyl-CoAs by long-chain-enoyl-CoA hydratase(EC 4.2.1.74), which forms and dehydrogenates D-3(3R)-hydroxyacyl-CoAs. (PMID: 9325339). 3-Oxooctanoyl-CoA is the substrate of the acetyl-CoA C-acyltransferase/oxoacyl-CoA thiolase A (EC 2.3.1.16, SCP2/3-oxoacyl-CoA thiolase) present in peroxisomes from normal liver.
w Hydroxy testosterone
This compound belongs to the family of Androgens and Derivatives. These are hydroxylated C19 steroid hormones. They are known to favour the development of masculine characteristics. They also show profound effects on scalp and body hair in humans
19-Oxoandrost-4-ene-3,17-dione
19-Oxoandrost-4-ene-3,17-dione is an intermediate in Androgen and estrogen metabolism. 19-Oxoandrost-4-ene-3,17-dione is the 4th to last step in the synthesis of 2-Methoxyestrone 3-glucuronide. It is generated from 19-Hydroxyandrost-4-ene-3,17-dione and then converted to Estrone. [HMDB] 19-Oxoandrost-4-ene-3,17-dione is an intermediate in Androgen and estrogen metabolism. 19-Oxoandrost-4-ene-3,17-dione is the 4th to last step in the synthesis of 2-Methoxyestrone 3-glucuronide. It is generated from 19-Hydroxyandrost-4-ene-3,17-dione and then converted to Estrone. D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
3-Sulfopyruvic acid
Sulfopyruvate, also known as 2-carboxy-2-oxoethanesulfonic acid or beta-sulfopyruvic acid, belongs to alpha-keto acids and derivatives class of compounds. Those are organic compounds containing an aldehyde substituted with a keto group on the adjacent carbon. Sulfopyruvate is soluble (in water) and an extremely strong acidic compound (based on its pKa). Sulfopyruvate can be found in a number of food items such as french plantain, sago palm, sweet cherry, and ostrich fern, which makes sulfopyruvate a potential biomarker for the consumption of these food products. Sulfopyruvate exists in all living organisms, ranging from bacteria to humans. 3-Sulfopyruvic acid is the product of the transamination of cysteinesulfonate in a reaction catalyzed by aspartate aminotransferase. 3-sulfopyruvic acid is stable and is reduced by malate dehydrogenase to beta-sulfolactate, which is excreted in the urine. Cysteinesulfonate, 3-sulfopyruvic acid, and beta-sulfolactate are reversibly interconverted in vivo. (PMID: 3346220).
3-Methoxy-4-hydroxyphenylglycolaldehyde
3-Methoxy-4-hydroxyphenylglycolaldehyde is the monoamine oxidase (MAO) aldehyde metabolite of metanephrine. Metanephrine is an O-methylated metabolite formed by catechol-O-methyltransferase (COMT) from epinephrine. Catecholamines play an important role in platelet activation and aggregation, epinephrine being the most potent one. Catecholamines are substantially increased during stress, exercise or smoking and could result in clinically important platelet activation if their action was not rapidly regulated. The inhibitory effects of methoxy phenolic derivatives on epinephrine-induced platelet aggregation may possibly be attributed to their free radical scavenging properties. There is substantial evidence to conclude that an internal rapid autoregulation of epinephrine-induced platelet aggregation, caused by its metabolic degradation products, takes place in vivo. (PMID: 11958479, 9706478) [HMDB]. 3-Methoxy-4-hydroxyphenylglycolaldehyde is found in many foods, some of which are nutmeg, peach (variety), common oregano, and olive. 3-Methoxy-4-hydroxyphenylglycolaldehyde is the monoamine oxidase (MAO) aldehyde metabolite of metanephrine. Metanephrine is an O-methylated metabolite formed by catechol-O-methyltransferase (COMT) from epinephrine. Catecholamines play an important role in platelet activation and aggregation, epinephrine being the most potent one. Catecholamines are substantially increased during stress, exercise or smoking and could result in clinically important platelet activation if their action was not rapidly regulated. The inhibitory effects of methoxy phenolic derivatives on epinephrine-induced platelet aggregation may possibly be attributed to their free radical scavenging properties. There is substantial evidence to conclude that an internal rapid autoregulation of epinephrine-induced platelet aggregation, caused by its metabolic degradation products, takes place in vivo. (PMID: 11958479, 9706478).
2-Octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone
7-Hydroxy-6-methyl-8-ribityl lumazine
7-Hydroxy-6-methyl-8-ribityl lumazine is an intermediate in Riboflavin metabolism. it is converted from 6,7-Dimethyl-8-(1-D-ribityl)lumazine. [HMDB] 7-Hydroxy-6-methyl-8-ribityl lumazine is an intermediate in Riboflavin metabolism. it is converted from 6,7-Dimethyl-8-(1-D-ribityl)lumazine.
5-(5-(2,6-Dichloro-4-(4,5-Dihydro-2-Oxazoly)phenoxy)pentyl)-3-Methyl Isoxazole
2,5-dichloro-2,5-cyclohexadiene-1,4-diol
A cyclohexadienediol that is cyclohexa-2,5-diene-1,4-diol in which positions 2 and 5 are substituted by chlorines.
berythromycin
An erythromycin that consists of erythronolide B having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively. D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents C784 - Protein Synthesis Inhibitor > C261 - Macrolide Antibiotic C254 - Anti-Infective Agent > C258 - Antibiotic
Isopropamide
Isopropamide is only found in individuals that have used or taken this drug. It is a long-acting quaternary anticholinergic drug. It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.Anticholinergics are a class of medications that inhibit parasympathetic nerve impulses by selectively blocking the binding of the neurotransmitter acetylcholine to its receptor in nerve cells. The nerve fibers of the parasympathetic system are responsible for the involuntary movements of smooth muscles present in the gastrointestinal tract. Inhibition here decreases acidity and motility, aiding in the treatment of gastrointestinal disorders. A - Alimentary tract and metabolism > A03 - Drugs for functional gastrointestinal disorders > A03A - Drugs for functional gastrointestinal disorders > A03AB - Synthetic anticholinergics, quaternary ammonium compounds C78272 - Agent Affecting Nervous System > C66880 - Anticholinergic Agent
3,6-dichlorocatechol
3,6-dichlorocatechol, also known as 3,6-dichloro-1,2-benzenediol, is a member of the class of compounds known as 3-chlorocatechols. 3-chlorocatechols are chlorocatechols with the chlorine atom attached at position C3 of the benzene ring. 3,6-dichlorocatechol is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). 3,6-dichlorocatechol can be found in a number of food items such as gooseberry, jicama, nutmeg, and lingonberry, which makes 3,6-dichlorocatechol a potential biomarker for the consumption of these food products.
Phenindamine
Phenindamine is an antihistamine. Phenindamine blocks the effects of the naturally occurring chemical histamine in your body. Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. It is used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold. Symptoms of a phenindamine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures. R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist
D-glycero-D-manno-Heptose 1-phosphate
Metocurine
D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents > D009466 - Neuromuscular Blocking Agents C78281 - Agent Affecting Musculoskeletal System > C29696 - Muscle Relaxant
Fluphenazine enanthate
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent
2-Hydroxy-6-oxo-(2-aminophenyl)-hexa-2,4-dienoate
Glucocochlearin
Glucocochlearin, also known as 1-methylpropyl glucosinolate, is a member of the class of compounds known as alkylglucosinolates. Alkylglucosinolates are organic compounds containing a glucosinolate moiety that carries an alkyl chain. Glucocochlearin is soluble (in water) and an extremely strong acidic compound (based on its pKa). Glucocochlearin can be found in a number of food items such as horseradish tree, horseradish, wasabi, and white mustard, which makes glucocochlearin a potential biomarker for the consumption of these food products.
Albafuran A
Albafuran A is found in fruits. Albafuran A is a constituent of white mulberry (Morus alba) Constituent of white mulberry (Morus alba). Albafuran A is found in fruits.
Senegin II
A triterpenoid saponin isolated from Polygala senega var latifolia and has been shown to exhibit hypoglycemic activity.
Aurasperone D
Aurasperone D is found in mango. Aurasperone D is a mycotoxin from Aspergillus niger infected mango fruits. Mycotoxin from Aspergillus niger infected mango fruits. Aurasperone D is found in mango.
Rhazin
Akuammidine is a natural product found in Aspidosperma quebracho-blanco, Tabernaemontana citrifolia, and other organisms with data available.
tinyatoxin
A heteropentacyclic compound found in Euphorbia poissonii with molecular formula C36H38O8. It is an agonist of the transient receptor potential cation channel subfamily V member 1 (TrpV1).
Arbusculin A
A sesquiterpene lactone isolated from Saussureae Radix and has been shown to exhibit inhibitory activity against melanogenesis.
Epilubimin
Stress product from potato tubers. Lubimin is found in eggplant and potato. Lubimin is found in eggplant. Stress product from potato tuber
Rishitin
Constituent of the tubers of white potatoes (Solanum subspecies) infected by Phytophthora infestans. Rishitin is found in many foods, some of which are pepper (c. annuum), yellow bell pepper, red bell pepper, and garden tomato (variety). Rishitin is found in alcoholic beverages. Rishitin is a constituent of the tubers of white potatoes (Solanum species) infected by Phytophthora infestans
Pollinastanol
Pollinastanol is found in dandelion. Pollinastanol is isolated from Smilax medica (Sarsaparilla
Swertiaperennin
2-O-methylswertianin is a member of the class of xanthones that is swertianin in which the hydroxy group at position 2 has been replaced by a methoxy group. It has a role as a plant metabolite. It is a member of xanthones, an aromatic ether and a polyphenol. It is functionally related to a swertianin. 1,8-Dihydroxy-2,6-dimethoxy-9H-xanthen-9-one is a natural product found in Gentiana orbicularis, Swertia japonica, and other organisms with data available. A member of the class of xanthones that is swertianin in which the hydroxy group at position 2 has been replaced by a methoxy group.
Isodiospyrin
Isodiospyrin is a member of biphenyls. Isodiospyrin is a natural product found in Diospyros morrisiana, Diospyros verrucosa, and other organisms with data available. Isodiospyrin, a natural dimeric naphthoquinone, is a human DNA topoisomerase I (Topoisomerase) inhibitor. Isodiospyrin can prevent both DNA relaxation and kinase activities of human topoisomerase I. Isodiospyrin shows anticancer, antibacterial and antifungal activities[1][2][3]. Isodiospyrin, a natural dimeric naphthoquinone, is a human DNA topoisomerase I (Topoisomerase) inhibitor. Isodiospyrin can prevent both DNA relaxation and kinase activities of human topoisomerase I. Isodiospyrin shows anticancer, antibacterial and antifungal activities[1][2][3].
5-O-Methylembelin
5-O-Methylembelin is a constituent of Myrsine africana (cape myrtle). Constituent of Myrsine africana (cape myrtle) 5-O-Methylembelin is a natural isocoumarin that inhibits PCSK9, inducible degrader of the low-density lipoprotein receptor (IDLR), and sterol regulatory element binding protein 2 (SREBP2) mRNA expression[1].
Phaseollinisoflavan
Phytoalexin from Phaseolus vulgaris (kidney bean), other Phaseolus subspecies and Glycyrrhiza glabra (licorice). Phaseollinisoflavan is found in many foods, some of which are green bean, yellow wax bean, herbs and spices, and common bean. Phaseollinisoflavan is found in common bean. Phytoalexin from Phaseolus vulgaris (kidney bean), other Phaseolus species and Glycyrrhiza glabra (licorice
Sophoraisoflavanone A
A hydroxyisoflavanone that is isoflavanone substituted by hydroxy groups at positions 5, 7 and 4, a methoxy substituent at position 2 and a prenyl group at position 3.
Multifidol
A butanone that is the 2-methylbutanoyl derivative of phloroglucinol.
protoveratrine B
Apoatropine
Etaconazole
N-Ethylphenylacetamide
A monocarboxylic acid amide obtained by formal condensation of the carboxy group of phenylacetic acid with the amino group of ethylamine.
N-(Hydrocinchonidin-8-yl)-4-azido-2-hydroxybenzamide
omega-COOH-LTE4NAc
magnesium;methyl (3R,21S,22S)-11,16-bis(ethenyl)-12,17,21,26-tetramethyl-4-oxo-22-[3-oxo-3-[(E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enoxy]propyl]-23,25-diaza-7,24-diazanidahexacyclo[18.2.1.15,8.110,13.115,18.02,6]hexacosa-1,5,8(26),9,11,13(25),14,16,18,20(23)-decaene-3-carboxylate
10-Deoxymethynolide
A macrolide that consists of oxacyclododec-9-ene-2,8-dione bearing four methyl substituents at positions 3, 5, 7 and 11 as well as a hydroxy group at position 4 and an ethyl substituent at position 12. The aglycone of the macrolide antibiotic 10-deoxymethymycin.
Narbonolide
A 14-membererd macrolide containing seven stereocentres carrying one ethyl, one hydroxy and five methyl substituents. It is the aglycone of the antibiotic narbonomycin and an intermediate in the biosynthesis of pikromycin.
Bisnoryangonin
Bisnoryangonin is a member of the class of compounds known as styrenes. Styrenes are organic compounds containing an ethenylbenzene moiety. Bisnoryangonin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Bisnoryangonin can be found in a number of food items such as pepper (c. baccatum), celeriac, french plantain, and olive, which makes bisnoryangonin a potential biomarker for the consumption of these food products.
dTDP-beta-L-daunosamine
A dTDP-sugar having beta-L-daunosamine as the sugar component.
5,8-Diethoxypsoralen
D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins D002317 - Cardiovascular Agents > D026902 - Potassium Channel Blockers D049990 - Membrane Transport Modulators
m-Cresotic acid
A monohydroxybenzoic acid consisting of salicylic acid having a methyl group at the 4-position.
DHT benzoate
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Tridecanol
1-tridecanol is a long chain fatty alcohol with a C-13 carbon back bone. It was found to be the most effective for controlling cariogenic bacterium. [HMDB] 1-tridecanol is a long chain fatty alcohol with a C-13 carbon back bone. It was found to be the most effective for controlling cariogenic bacterium.
m-Ethyl_toluene
m-Ethyl_toluene belongs to the family of Toluenes. These are compounds containing a benzene ring which bears a methane group.
4-t-Butylbenzoic acid
CONFIDENCE standard compound; INTERNAL_ID 218; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4630; ORIGINAL_PRECURSOR_SCAN_NO 4625 CONFIDENCE standard compound; INTERNAL_ID 218; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4617; ORIGINAL_PRECURSOR_SCAN_NO 4616 CONFIDENCE standard compound; INTERNAL_ID 218; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4640; ORIGINAL_PRECURSOR_SCAN_NO 4636 CONFIDENCE standard compound; INTERNAL_ID 218; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4710; ORIGINAL_PRECURSOR_SCAN_NO 4706 CONFIDENCE standard compound; INTERNAL_ID 218; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4650; ORIGINAL_PRECURSOR_SCAN_NO 4645 CONFIDENCE standard compound; INTERNAL_ID 218; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4623; ORIGINAL_PRECURSOR_SCAN_NO 4620
Karphos
CONFIDENCE standard compound; INTERNAL_ID 790; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9696; ORIGINAL_PRECURSOR_SCAN_NO 9695 CONFIDENCE standard compound; INTERNAL_ID 790; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9735; ORIGINAL_PRECURSOR_SCAN_NO 9730 CONFIDENCE standard compound; INTERNAL_ID 790; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9644; ORIGINAL_PRECURSOR_SCAN_NO 9642 CONFIDENCE standard compound; INTERNAL_ID 790; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9682; ORIGINAL_PRECURSOR_SCAN_NO 9680 CONFIDENCE standard compound; INTERNAL_ID 790; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9725; ORIGINAL_PRECURSOR_SCAN_NO 9724 CONFIDENCE standard compound; INTERNAL_ID 790; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9709; ORIGINAL_PRECURSOR_SCAN_NO 9708
Tetrahydrodeoxycortisol
Tetrahydrodeoxycortisol (THS) is a mineralocorticoid, the main urinary metabolite of 11-deoxycortisol. THS excretion is significantly associated with tetrahydroaldosterone excretion, total androgen excretion, and cortisol metabolites. Aldosterone synthesis is highly heritable and is affected by genotype at CYP11B1. Variation in the region of chromosome 8 including the genes steroid 11-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) influences mineralocorticoid and glucocorticoid metabolism; differences in 11-hydroxylation efficiency can have downstream effects on mineralocorticoid synthesis. Such effects may be of relevance to the development of low-renin essential hypertension. Genotype differences in CYP11B1 explains approx. 5\\% of the variance in urinary THS excretion in the population. Excretion of THS is heritable (19.4\\%) and the T-allele of the −344 C/T polymorphism of CYP11B2 is more strongly assocd. with higher THS levels than the C-allele. (PMID: 16984984, 15522937, 15272911) [HMDB] Tetrahydrodeoxycortisol (THS) is a mineralocorticoid, the main urinary metabolite of 11-deoxycortisol. THS excretion is significantly associated with tetrahydroaldosterone excretion, total androgen excretion, and cortisol metabolites. Aldosterone synthesis is highly heritable and is affected by genotype at CYP11B1. Variation in the region of chromosome 8 including the genes steroid 11-beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) influences mineralocorticoid and glucocorticoid metabolism; differences in 11-hydroxylation efficiency can have downstream effects on mineralocorticoid synthesis. Such effects may be of relevance to the development of low-renin essential hypertension. Genotype differences in CYP11B1 explains approximately 5\\% of the variance in urinary THS excretion in the population. Excretion of THS is heritable (19.4\\%) and the T-allele of the -344 C/T polymorphism of CYP11B2 is more strongly associated with higher THS levels than the C-allele. (PMID: 16984984, 15522937, 15272911). D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Androstane-3,17-diol dipropionate
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
2-chloro-4-biphenylol
CONFIDENCE standard compound; INTERNAL_ID 1048; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5119; ORIGINAL_PRECURSOR_SCAN_NO 5116 CONFIDENCE standard compound; INTERNAL_ID 1048; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5104; ORIGINAL_PRECURSOR_SCAN_NO 5103 CONFIDENCE standard compound; INTERNAL_ID 1048; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5184; ORIGINAL_PRECURSOR_SCAN_NO 5183 CONFIDENCE standard compound; INTERNAL_ID 1048; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5105; ORIGINAL_PRECURSOR_SCAN_NO 5101 CONFIDENCE standard compound; INTERNAL_ID 1048; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5089; ORIGINAL_PRECURSOR_SCAN_NO 5088 CONFIDENCE standard compound; INTERNAL_ID 1048; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5081; ORIGINAL_PRECURSOR_SCAN_NO 5079
1-nitrosonaphthalene
1-nitrosonaphthalene is considered to be practically insoluble (in water) and basic
1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene
This compound belongs to the family of Peptides. These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another.
1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene
This compound belongs to the family of Peptides. These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another.
1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene
This compound belongs to the family of Peptides. These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another.
1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene
This compound belongs to the family of Peptides. These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another.
11H-14,15-EETA
11H-14,15-EETA is an epoxyeicosatrienoic acid. Epoxyeicosatrienoic acids (EpETrEs) have been reported recently having vasodilatory effects and a role of P-450-dependent arachidonic acid monooxygenase metabolites is suggested in vasoregulation. The physiological role of this compound has not been totally established, although in other tissues EpETrEs are mainly involved in hormone production and in the vascular and renal systems. Some studies have implicated epoxygenase metabolites of arachidonic acid in the control of steroidogenesis in luteinised granulosa cells. (PMID: 12749593, 12361727, 1650001) [HMDB] 11H-14,15-EETA is an epoxyeicosatrienoic acid. Epoxyeicosatrienoic acids (EpETrEs) have been reported recently having vasodilatory effects and a role of P-450-dependent arachidonic acid monooxygenase metabolites is suggested in vasoregulation. The physiological role of this compound has not been totally established, although in other tissues EpETrEs are mainly involved in hormone production and in the vascular and renal systems. Some studies have implicated epoxygenase metabolites of arachidonic acid in the control of steroidogenesis in luteinised granulosa cells. (PMID: 12749593, 12361727, 1650001).
Bromobenzene-3,4-oxide
This compound belongs to the family of Epoxides. These are compounds containing a cyclic ether with three ring atoms(one oxygen and two carbon atoms)Volume 18, Issue 17, 4 September 2007, Pages 2001-2010) ; [2] A. Trabocchi, D. Scarpi, and A. Guarna. 2007. Structural diversity of bicyclic amino acids. Amino Acids (2008) 34: 1-24. DOI 10.1007/s00726-007-0588-y
Benzo[a]pyrene-7,8-oxide
This compound belongs to the family of Pyrenes. These are compounds containing a pyrene moiety, which consists four fused benzene rings, resulting in a flat aromatic system.
2-BUTYL-3-(3,5-DIIODO-4-HYDROXYBENZOYL) BENZOFURAN
17beta-Acetylestradiol
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones β-Estradiol 17-acetate is a metabolite of estradiol. Target: Others β-Estradiol 17-acetate is a metabolite of estradiol.
1,2-Dihydroxy-3-keto-5-methylthiopentene
At physiological pH, this molecule, 1,2-dihydroxy-3-keto-5-methylthiopentene, is a monoanion, 1,2-dihydroxy-3-keto-5-methylthiopentene anion. 1,2-dihydroxy-3-keto-5-methylthiopentene anion, an aci-reductone, is believed to be an unstable intermediate in the methionine salvage pathway in Klebsiella pneumoniae. (MetaCyc).
ST 28:0;O3
Typhasterol in which the oxygen atom of the keto group has been substituted by two hydrogen atoms. A member of a biosynthetic pathway to castasterone, it has been isolated from the primary roots of maize.
Hydroxyspheroidene
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
Chlorobactene
A carotenoid that is 1,2,4-trimethylmenzene in which the hydrogen at position 3 has been replaced by an all-trans-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,23-undecaen-1-yl group. Found in photosynthetic green bacteria. D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
6-(alpha-D-Glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate
A myo-inositol cyclic phosphate that is 1D-myo-inositol 1,2-cyclic phosphate having an alpha-D-glucosaminyl residue attached at the 6-position.
Medicocarpin
Isolated from roots of Medicago sativa (alfalfa) and Trifolium repens (white clover). Medicocarpin is found in many foods, some of which are alfalfa, herbs and spices, pulses, and tea. Medicocarpin is found in alfalfa. Medicocarpin is isolated from roots of Medicago sativa (alfalfa) and Trifolium repens (white clover). Medicarpin 3-O-glucoside. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=52766-70-8 (retrieved 2024-08-20) (CAS RN: 52766-70-8). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
7,8-Dihydro-beta-carotene
A cyclic carotene that is beta-carotene which the double bond between positions 7 and 8 has been hydrogenated.
FA 18:4;O
A long-chain, divinyl ether fatty acid composed of 8-nonenoic acid in which the E-hydrogen at position 9 is substituted by a (1E,3Z,6Z)-nona-1,3,6-trien-1-yloxy group.
4-hydroxylamino-2,6-dinitrotoluene
4-hydroxylamino-2,6-dinitrotoluene, also known as 4-hadnt, is a member of the class of compounds known as dinitrotoluenes. Dinitrotoluenes are organic aromatic compounds containing a benzene that carries a single methyl group and exactly two nitro groups. 4-hydroxylamino-2,6-dinitrotoluene is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 4-hydroxylamino-2,6-dinitrotoluene can be found in a number of food items such as elderberry, pigeon pea, tea leaf willow, and tree fern, which makes 4-hydroxylamino-2,6-dinitrotoluene a potential biomarker for the consumption of these food products.
13Z-docosenoyl-CoA
13Z-docosenoyl-CoA is also known as C22:1(N-9) -CoA or Erucyl-CoA. 13Z-docosenoyl-CoA is considered to be practically insoluble (in water) and acidic. 13Z-docosenoyl-CoA is a fatty ester lipid molecule
Aldoifosfamide
Aldoifosfamide is a metabolite of ifosfamide. Ifosfamide (pronounced eye. fos. fa. mide) (also marketed as Mitoxana and Ifex) is a nitrogen mustard alkylating agent used in the treatment of cancer. It is sometimes abbreviated IFO. (Wikipedia)
6-Mercaptopurine ribonucleoside triphosphate
6-Mercaptopurine ribonucleoside triphosphate is a metabolite of mercaptopurine. Mercaptopurine (also called 6-mercaptopurine, 6-MP or its brand name Purinethol) is an immunosuppressive drug. It is a thiopurine. (Wikipedia)
N,N-Diethylglycine
An N-alkyl glycine that is glycine in which the amino group is replaced by a diethylnitrilo group.
Neosurugatoxin
D009676 - Noxae > D011042 - Poisons > D008978 - Mollusk Venoms D009676 - Noxae > D011042 - Poisons > D008387 - Marine Toxins D009676 - Noxae > D011042 - Poisons > D014688 - Venoms
Ophiobolene
A sesterterpenoid that is (7Z)-ophiobola-7,19-diene carrying a hydroxy substituent at position 3.
Homomethionine
Homomethionine (CAS: 6094-76-4) belongs to the class of organic compounds known as alpha-amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). Homomethionine is possibly neutral. Homomethionine has been detected, but not quantified in, several different foods, such as lima beans, red huckleberries, catjang pea, Chinese chestnuts, and pepper (C. annuum). This could make homomethionine a potential biomarker for the consumption of these foods. Homomethionine is found in brassicas and is isolated from cabbage and horseradish. Isolated from cabbage and horseradish. L-2-Amino-5-(methylthio)pentanoic acid is found in many foods, some of which are pepper (c. frutescens), vanilla, cauliflower, and pineappple sage.
gamma-Terpineol
gamma-Terpineol is found in ceylan cinnamon. gamma-Terpineol is isolated from carrot oils, from the cinnamon tree (Cinnamomum zeylanicum) and Scotch pine (Pinus sylvestris).Terpineol is a naturally occurring monoterpene alcohol that has been isolated from a variety of sources such as cajuput oil, pine oil, and petitgrain oil. There are three isomers, alpha-, beta-, and gamma-terpineol, the last two differing only by the location of the double bond. Terpineol is usually a mixture of these isomers with alpha-terpineol as the major constituent. (Wikipedia). Isolated from carrot oils, from the cinnamon tree (Cinnamomum zeylanicum) and Scotch pine (Pinus sylvestris)
3,3-Diethyl-2,4-dioxopiperidine
R - Respiratory system > R05 - Cough and cold preparations > R05D - Cough suppressants, excl. combinations with expectorants C78273 - Agent Affecting Respiratory System > C66917 - Antitussive Agent
Albaflavenone
A carbotricyclic compound that is (+)-epi-isozizaene in which the hydrogens at position 5 have been replaced by an oxo group.
(S)-3-Hydroxyisobutyryl-CoA
(S)-3-Hydroxyisobutyryl-CoA is s metabolite of 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4 ) during beta-alanine metabolism (KEGG 00410), propanoate metabolism (KEGG 00640), and valine, leucine and isoleucine degradation (KEGG 00280). Deficiencies of this enzyme in valine degradation can result in hypotonia, poor feeding, motor delay, and subsequent neurological regression in infancy, episodes of ketoacidosis and Leigh-like changes in the basal ganglia on a magnetic resonance imaging scan (PMID 17160907). [HMDB] (S)-3-Hydroxyisobutyryl-CoA is s metabolite of 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4 ) during beta-alanine metabolism (KEGG 00410), propanoate metabolism (KEGG 00640), and valine, leucine and isoleucine degradation (KEGG 00280). Deficiencies of this enzyme in valine degradation can result in hypotonia, poor feeding, motor delay, and subsequent neurological regression in infancy, episodes of ketoacidosis and Leigh-like changes in the basal ganglia on a magnetic resonance imaging scan (PMID 17160907).
1,2-Cyclohexanediol, 1-methyl-4-(1-methylethenyl)-
P-mentha-8(9)-en-1,2-diol, also known as 1-methyl-4-(1-methylethenyl)-1,2-cyclohexanediol, is a member of the class of compounds known as menthane monoterpenoids. Menthane monoterpenoids are monoterpenoids with a structure based on the o-, m-, or p-menthane backbone. P-menthane consists of the cyclohexane ring with a methyl group and a (2-methyl)-propyl group at the 1 and 4 ring position, respectively. The o- and m- menthanes are much rarer, and presumably arise by alkyl migration of p-menthanes. P-mentha-8(9)-en-1,2-diol is soluble (in water) and a very weakly acidic compound (based on its pKa). P-mentha-8(9)-en-1,2-diol can be found in wild celery, which makes P-mentha-8(9)-en-1,2-diol a potential biomarker for the consumption of this food product.
(E)-1-O-Cinnamoyl-beta-D-glucose
(E)-1-O-Cinnamoyl-beta-D-glucose is found in fruits. (E)-1-O-Cinnamoyl-beta-D-glucose is a constituent of Vaccinium vitis-idaea (cowberry)
CMP-N-glycoloyl-beta-neuraminate(2-)
CMP-N-glycoloyl-beta-neuraminate(2-) is also known as CMP-N-Glycoloyl-beta-neuraminic acid. CMP-N-glycoloyl-beta-neuraminate(2-) is considered to be soluble (in water) and acidic
19-Hydroxytestosterone
19-Hydroxytestosterone is an intermediate in Androgen and estrogen metabolism. 19-Hydroxytestosterone is the 4th to last step in the synthesis of 16-Glucuronide-estriol. It is generated from Testosterone via the enzyme cytochrome P450 (EC 1.14.14.1) and then converted to 19-Oxotestosterone.
Phosphodimethylethanolamine
Phosphomonomethylethanolamine, phosphodimethylethanolamine and phosphocholine were weak competitive inhibitors of the cytidylyltransferase catalyzed reaction when phosphoethanolamine was used as a substrate, with Ki values of 7.0, 6.8 and 52.9 mM, respectively. (PMID: 8130268) Unlike the plant and Plasmodium PEAMT, which catalyze all three methylations in the pathway, PMT-2 catalyzes only the last two steps in the pathway, i.e., the methylation of phosphomonomethylethanolamine (P-MME) to phosphodimethylethanolamine (P-DME) and of P-DME to phosphocholine. (PMID: 16681378)
(10E,12Z)-(9S)-9-Hydroperoxyoctadeca-10,12-dienoic acid
(9s,10e,12z,15z)-9-hydroperoxy-10,12,15-octadecadienoate, also known as 9(S)-hpod or 9-hydroperoxy-11,12-octadecadienoic acid, belongs to lineolic acids and derivatives class of compounds. Those are derivatives of lineolic acid. Lineolic acid is a polyunsaturated omega-6 18 carbon long fatty acid, with two CC double bonds at the 9- and 12-positions. Thus, (9s,10e,12z,15z)-9-hydroperoxy-10,12,15-octadecadienoate is considered to be an octadecanoid lipid molecule (9s,10e,12z,15z)-9-hydroperoxy-10,12,15-octadecadienoate is practically insoluble (in water) and a weakly acidic compound (based on its pKa). (9s,10e,12z,15z)-9-hydroperoxy-10,12,15-octadecadienoate can be found in a number of food items such as burdock, oat, parsnip, and cocoa bean, which makes (9s,10e,12z,15z)-9-hydroperoxy-10,12,15-octadecadienoate a potential biomarker for the consumption of these food products. (10E,12Z)-(9S)-9-Hydroperoxyoctadeca-10,12-dienoic acid, also known as 9(S)-HPOD or (9S,10E,12Z)-9-Hydroperoxy-10,12-octadecadienoate, is classified as a lineolic acid or a Lineolic acid derivative. Lineolic acids are derivatives of lineolic acid. Lineolic acid is a polyunsaturated omega-6 18 carbon long fatty acid, with two CC double bonds at the 9- and 12-positions. (10E,12Z)-(9S)-9-Hydroperoxyoctadeca-10,12-dienoic acid is considered to be practically insoluble (in water) and acidic. (10E,12Z)-(9S)-9-Hydroperoxyoctadeca-10,12-dienoic acid is an octadecanoid lipid molecule. (10E,12Z)-(9S)-9-Hydroperoxyoctadeca-10,12-dienoic acid can be found throughout numerous foods such as Barley, Prunus (Cherry, Plum), Cherimoya, and Prairie turnips D004791 - Enzyme Inhibitors > D016859 - Lipoxygenase Inhibitors D009676 - Noxae > D016877 - Oxidants > D010545 - Peroxides
Racemethorphan
D018377 - Neurotransmitter Agents > D018683 - Excitatory Amino Acid Agents > D018691 - Excitatory Amino Acid Antagonists D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids D019141 - Respiratory System Agents > D000996 - Antitussive Agents D002491 - Central Nervous System Agents
2-Deoxy-2,3-dehydro-n-acetyl-neuraminic acid
BENZOYLARGININE NITROANILIDE
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D002863 - Chromogenic Compounds D004396 - Coloring Agents
N-acetyl Leukotriene E4
Risbitin
Risbitin, also known as rishitin, (1s-(1alpha,2beta,3alpha,7beta))-isomer, is a member of the class of compounds known as 1,2-diols. 1,2-diols are polyols containing an alcohol group at two adjacent positions. Risbitin is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Risbitin can be found in potato, which makes risbitin a potential biomarker for the consumption of this food product.
ent-16-Kauren-19-ol
ent-16-Kauren-19-ol, also known as ent-kaurenol or kaur-16-en-18-ol, belongs to the class of organic compounds known as kaurane diterpenoids. These are diterpene alkaloids with a structure that is based on the kaurane skeleton. Kaurane is a tetracyclic compound that arises by cyclisation of a pimarane precursor followed by rearrangement. It possesses a [3,2,1]-bicyclic ring system with C15-C16 bridge connected to C13, forming the five-membered ring D. ent-16-Kauren-19-ol is an extremely weak basic (essentially neutral) compound (based on its pKa).
trimethylalanine
A beta-alanine derivative arising from quaternisation of the nitrogen of beta-alanine with three methyl groups and removal of the proton attached to the carboxy group. It is an osmoprotective compound accumulated by most members of the highly stress-tolerant Plumbaginaceae family. β-alanine betaine, also known as beta-homobetaine or propiobetaine, is a member of the class of compounds known as tetraalkylammonium salts. Tetraalkylammonium salts are organonitrogen compounds containing a quaternary ammonium substituted with four alkyl chains. β-alanine betaine is practically insoluble (in water) and a weakly acidic compound (based on its pKa). β-alanine betaine can be found in a number of food items such as cabbage, ohelo berry, olive, and common salsify, which makes β-alanine betaine a potential biomarker for the consumption of these food products.
Demethylmedicarpin
(6ar,11ar)-3,9-dihydroxypterocarpan is a member of the class of compounds known as pterocarpans. Pterocarpans are benzo-pyrano-furano-benzene compounds, containing the 6H-[1]benzofuro[3,2-c]chromene skeleton. They are derivatives of isoflavonoids. Thus, (6ar,11ar)-3,9-dihydroxypterocarpan is considered to be a flavonoid lipid molecule (6ar,11ar)-3,9-dihydroxypterocarpan is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). (6ar,11ar)-3,9-dihydroxypterocarpan can be found in a number of food items such as bayberry, sweet bay, agave, and red bell pepper, which makes (6ar,11ar)-3,9-dihydroxypterocarpan a potential biomarker for the consumption of these food products.
5-O-Methylembelin
5-O-methyl embelin is a member of the class of monohydroxy-1,4-benzoquinones that is embelin in which the hydroxy group at position 5 is replaced by a methoxy group. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antileishmanial activity as well as inhibitory activity towards hepatitis C protease. It has a role as a metabolite, a hepatitis C protease inhibitor, an antileishmanial agent and an antineoplastic agent. It is an enol ether and a member of monohydroxy-1,4-benzoquinones. It is functionally related to an embelin. 5-O-Methylembelin is a natural product found in Lysimachia punctata, Embelia schimperi, and other organisms with data available. 5-O-Methylembelin is a constituent of Myrsine africana (cape myrtle). Constituent of Myrsine africana (cape myrtle) 5-O-Methylembelin is a natural isocoumarin that inhibits PCSK9, inducible degrader of the low-density lipoprotein receptor (IDLR), and sterol regulatory element binding protein 2 (SREBP2) mRNA expression[1].
Benzoylecgonine
CONFIDENCE standard compound; EAWAG_UCHEM_ID 2823
fluvastatin
C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent C471 - Enzyme Inhibitor > C1655 - HMG-CoA Reductase Inhibitor CONFIDENCE standard compound; EAWAG_UCHEM_ID 3136 Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].
MONOLINURON
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3173
thiethylperazine
R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AD - Phenothiazine derivatives D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent D005765 - Gastrointestinal Agents > D000932 - Antiemetics D002491 - Central Nervous System Agents Thiethylperazine, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine is also a selective ABCC1activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine has anti-emetic, antipsychotic and antimicrobial effects[1][2][3].
3-CMP
A cytidine 3-phosphate compound with a monophosphate group at the 3-position. relative retention time with respect to 9-anthracene Carboxylic Acid is 0.054 Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group[1]. Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group[1].
Melilotoside
E-4031
D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents
N-Methylanthranilic acid
An aromatic amino acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is substituted by a methyl group. 2-(Methylamino)benzoic acid is the main metabolite of methyl-N-methylanthranilates (MMA) (HY-76705) and is the compound in which the ester group is converted. MMA can be isolated from citrus fruits and has potential analgesic activity. 2-(Methylamino)benzoic acid was used to detect the metabolic levels of MMA in rat liver[1].
12-HETE-[d8]
PROCESSING averaging of repeated ion fragments at 30.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ]; CONFIDENCE standard compound; NATIVE_RUN_ID STD_neg_MSMS_1min0088.mzML CONFIDENCE standard compound; NATIVE_RUN_ID STD_neg_MSMS_1min0088.mzML; PROCESSING averaging of repeated ion fragments at 30.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID STD_neg_MSMS_1min0088.mzML; PROCESSING averaging of repeated ion fragments at 20.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID STD_neg_MSMS_1min0088.mzML; PROCESSING averaging of repeated ion fragments at 10.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001295.mzML; PROCESSING averaging of repeated ion fragments at 30.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001295.mzML; PROCESSING averaging of repeated ion fragments at 20.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001295.mzML; PROCESSING averaging of repeated ion fragments at 10.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001295.mzML; PROCESSING averaging of repeated ion fragments at 40.0 NCE within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001295.mzML; PROCESSING averaging of repeated ion fragments at 30.0 NCE within 5 ppm window [MS, MS:1000575, mean of spectra, ] CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001295.mzML; PROCESSING averaging of repeated ion fragments at 20.0 NCE within 5 ppm window [MS, MS:1000575, mean of spectra, ]
RESORCINOL MONOACETATE
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent Same as: D02393
AMINOCARB
C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor D010575 - Pesticides > D007306 - Insecticides D016573 - Agrochemicals
3alpha,7alpha-Dihydroxy-5beta-cholestan-26-oic acid
A cholestanoid that is 5beta-cholestan-26-oic acid substituted by alpha-hydroxy groups at positions 3 and 7 respectively.
3-oxodecanoyl-CoA
An oxo-fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxylic acid group of 3-oxodecanoic acid.
FA 5:1;O2
D018377 - Neurotransmitter Agents > D018847 - Opioid Peptides D018377 - Neurotransmitter Agents > D004399 - Dynorphins 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy. Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency.
CoA 20:3
CoA 10:1;O
anthraniloyl-CoA
A member of the class of benzoyl-CoAs having 2-aminobenzoyl as the S-acyl group.
CoA 22:1
ST 21:3;O5;S
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
carthamidin
A tetrahydroxyflavanone that is (S)-naringenin substituted by an additional hydroxy group at position 6.
β-Estradiol 17-acetate
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones β-Estradiol 17-acetate is a metabolite of estradiol. Target: Others β-Estradiol 17-acetate is a metabolite of estradiol.
Protirelina
H - Systemic hormonal preparations, excl. sex hormones and insulins > H01 - Pituitary and hypothalamic hormones and analogues > H01A - Anterior pituitary lobe hormones and analogues > H01AB - Thyrotropin
6-Fluoro-2,5-dioxo-2,3-dihydrospiro[chromene-4,4-imidazolidine]-2-carboxamide
Albafuran A
A member of the class of 1-benzofurans that is 1-benzofuran substituted by a hydroxy group at position 6 and a 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3,5-dihydroxyphenyl group at position 2.
Streptomycin C
AI3-05924
2-(Methylamino)benzoic acid is the main metabolite of methyl-N-methylanthranilates (MMA) (HY-76705) and is the compound in which the ester group is converted. MMA can be isolated from citrus fruits and has potential analgesic activity. 2-(Methylamino)benzoic acid was used to detect the metabolic levels of MMA in rat liver[1].
19-Hydroxytestosterone
A 3-oxo Delta(4)-steroid that is testosterone which is substituted by a hydroxy group at positions 19. 19-Hydroxytestosterone is an intermediate in Androgen and estrogen metabolism. 19-Hydroxytestosterone is the 4th to last step in the synthesis of 16-Glucuronide-estriol. It is generated from Testosterone via the enzyme cytochrome P450 (EC 1.14.14.1) and then converted to 19-Oxotestosterone. [HMDB]. 19-Hydroxytestosterone is found in many foods, some of which are hedge mustard, tinda, black walnut, and babassu palm.
CMP-N-glycoloyl-beta-neuraminate(2-)
CMP-N-glycoloyl-beta-neuraminate(2-) is also known as CMP-N-Glycoloyl-beta-neuraminic acid. CMP-N-glycoloyl-beta-neuraminate(2-) is considered to be soluble (in water) and acidic
3-Deoxyestrone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Stanolone benzoate
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
carbinoxamine
R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AA - Aminoalkyl ethers D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist
Phenindamine
R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist
Isopropamide
A - Alimentary tract and metabolism > A03 - Drugs for functional gastrointestinal disorders > A03A - Drugs for functional gastrointestinal disorders > A03AB - Synthetic anticholinergics, quaternary ammonium compounds C78272 - Agent Affecting Nervous System > C66880 - Anticholinergic Agent
fluphenazine enanthate
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent
4-Chlorophenylacetic acid
A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-chlorophenyl group.
Hypoglycin a
A diastereoisomeric mixture of (2S,4R)- and (2S,4S)- hypoglycin A, found in the edible part of the fruit of the Ackee, Blighia sapida (where the 2S,4R diastereoisomer is more dominant (17\\% d.e.) than its 2S,4S counterpart) as well as in the sycamore maple tree (Acer pseudoplatanus). D009676 - Noxae > D011042 - Poisons > D007005 - Hypoglycins
LYSERGAMIDE
An ergoline alkaloid comprising ergoline lacking hydrogens at positions 9 and 10 and also having a methyl group attached to the piperidine nitrogen.
2-acetyllactic acid
A derivative of butyric acid having methyl, hydroxy and oxo substituents at the 2-, 2- and 3-positions respectively.
gamma-linolenoyl-CoA
An octadecatrienoyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of gamma-linolenic acid.
1-(2,6-Dihydroxy-4-methoxyphenyl)-3-phenylpropan-1-one
2,3-cyclic ump
A 2,3-cyclic pyrimidine nucleotide in which uridine is the parent nucleoside.
O-Butanoylcarnitine
A C4-acylcarnitine that is the O-butanoyl derivative of carnitine.
8Z,11Z,14Z-eicosatrienoyl-CoA
An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of all-cis-icosa-8,11,14-trienoic acid.
3-Oxooctanoyl-CoA
An oxo-fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxylic acid group of 3-oxooctanoic acid.
erucoyl-CoA
An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of erucic acid.
15-dehydro-prostaglandin D2
The 15-dehydro derivative of prostaglandin D2.
2-Amino-4-hydroxy-6-pyrophosphoryl-methylpteridine
1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol
4-Methylene-L-glutamic acid
The L-enantiomer of 4-methyleneglutamic acid.
3-Methoxy-4-hydroxyphenylglycolaldehyde
A member of the class of glycolaldehydes that is 3,4-dihydroxymandelaldehyde in which the hydroxy group at position 4 is replaced by a methoxy group.
5-Formimidoyltetrahydrofolic acid
The 5-formimidoyl derivative of tetrahydrofolic acid.
Acetylpyruvic acid
A dioxo monocarboxylic acid that is pentanoic acid carrying two oxo groups at positions 2 and 4.
5-(5-(2,6-Dichloro-4-(4,5-Dihydro-2-Oxazoly)phenoxy)pentyl)-3-Methyl Isoxazole
CMP-N-Glycoloyl-beta-neuraminic acid
A CMP-N-acyl-beta-neuraminic acid in which the N-acyl group is glycoloyl.
Aconitane-7,8,14-triol, 20-ethyl-4-(methoxymethyl)-1,6,16-trimethoxy-, (1-alpha,6-beta,14-alpha,16-beta)-
3-Hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-octanamide
ascorbate 2-sulfate
D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D000924 - Anticholesteremic Agents D009676 - Noxae > D000963 - Antimetabolites
3,7-Dimethylocta-1,6-dien-3-yl phosphono hydrogen phosphate
N(6)-[(indol-3-yl)acetyl]-L-lysine
D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids
[(7S,11S,15R,19R,22R,26R,30S,34S,43S,47S,51R,55R,58R,62R,66S,70S)-38-(hydroxymethyl)-7,11,15,19,22,26,30,34,43,47,51,55,58,62,66,70-hexadecamethyl-1,4,37,40-tetraoxacyclodoheptacont-2-yl]methanol
(2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid
4-Hydroxylamino-2,6-dinitrotoluene
A member of the class of nitrotoluenes that is 2,6-dinitrotoluene bearing an additional hydroxylamino substituent at position 4.
cortisol 21-sulfate
A steroid sulfate obtained by the formal condensation of hydroxy group at position 21 of cortisol with sulfuric acid. D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
(S,E)-Zearalenone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D004967 - Estrogens D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins
3,5,14-trihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carboxaldehyde
1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene
1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene
1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene
1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene
7-Hydroxyisoflavone
The simplest member of the class of 7-hydroxyisoflavones that is isoflavone with a hydroxy substituent at position 7.