Gene Association: RND2

UniProt Search: RND2 (PROTEIN_CODING)
Function Description: Rho family GTPase 2

found 3 associated metabolites with current gene based on the text mining result from the pubmed database.

Etomidate

(R)-(+)-1-(alpha-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester

Etomidate is only found in individuals that have used or taken this drug. It is an midazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic. [PubChem]Etomidate binds at a distinct binding site associated with a Cl^- ionopore at the GABA_A receptor, increasing the duration of time for which the Cl^- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged. D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics N - Nervous system > N01 - Anesthetics > N01A - Anesthetics, general C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent

Isobutyronitrile

2-methylpropanenitrile

C4H7N (69.0578)

Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate

C14H16N2O2 (244.1212)