Gene Association: TNIP3

UniProt Search: TNIP3 (PROTEIN_CODING)
Function Description: TNFAIP3 interacting protein 3

found 14 associated metabolites with current gene based on the text mining result from the pubmed database.

hydroxymuconic semialdehyde

2-hydroxy-6-oxohexa-2,4-dienoic acid

C6H6O4 (142.0266)


   

3-Oxoadipic acid

3-Oxoadipic acid, disodium salt

C6H8O5 (160.0372)


3-Oxoadipic acid is a regularly occurring Adipic dicarboxylic acid human metabolite found occasionally in biofluids of healthy individuals. (PMIDs 8340451, 1769109, 2338430) Increased amounts of 3-Oxoadipic acid are excreted after ingestion of Sebacic acid, supporting the hypothesis that dicarboxylic acids are degraded by ordinary beta-oxidation. (PMID 3220884) [HMDB] 3-Oxoadipic acid is a regularly occurring Adipic dicarboxylic acid human metabolite found occasionally in biofluids of healthy individuals. (PMIDs 8340451, 1769109, 2338430) Increased amounts of 3-Oxoadipic acid are excreted after ingestion of Sebacic acid, supporting the hypothesis that dicarboxylic acids are degraded by ordinary beta-oxidation. (PMID 3220884).

   

2-Maleylacetate

(2Z)-4-oxohex-2-enedioic acid

C6H6O5 (158.0215)


This compound belongs to the family of Medium-chain Keto Acids and Derivatives. These are keto acids with a 6 to 12 carbon atoms long side chain

   

2,5-dichlorohydroquinone

2,5-Dichloro-1,4-benzenediol

C6H4Cl2O2 (177.9588)


A dichlorohydroquinone that is hydroquinone substituted by chloro groups at positions 2 and 5 respectively.

   

Chloroquinol

1,4-Dihydroxyl-2-chlorobenzene

C6H5ClO2 (143.9978)


   

beta-Hexachlorocyclohexane

(1alpha,2beta,3alpha,4beta,5alpha,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane

C6H6Cl6 (287.8601)


beta-Hexachlorocyclohexane is a by-product of the production of the insecticide lindane. It belongs to the family of Cycloalkanes. These are alkanes containing one or more saturated rings of carbon atoms. They consist of only carbon and hydrogen atoms and are saturated. P - Antiparasitic products, insecticides and repellents > P03 - Ectoparasiticides, incl. scabicides, insecticides and repellents > P03A - Ectoparasiticides, incl. scabicides > P03AB - Chlorine containing products A - Alimentary tract and metabolism > A09 - Digestives, incl. enzymes > A09A - Digestives, incl. enzymes > A09AA - Enzyme preparations

   

Lindane

(1alpha,2alpha,3beta,4alpha,5alpha,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane

C6H6Cl6 (287.8601)


An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports of resistance, neurotoxicity, and bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical treatment of pediculosis capitis (head lice), pediculosis pubis (pubic lice), or scabies in patients greater than two years of age who cannot tolerate or have failed first-line treatment. P - Antiparasitic products, insecticides and repellents > P03 - Ectoparasiticides, incl. scabicides, insecticides and repellents > P03A - Ectoparasiticides, incl. scabicides > P03AB - Chlorine containing products A - Alimentary tract and metabolism > A09 - Digestives, incl. enzymes > A09A - Digestives, incl. enzymes > A09AA - Enzyme preparations

   

Pepsin

1,2,3,4,5,6-Hexachlorocyclohexane

C6H6Cl6 (287.8601)


It is used in the preparation of fish meal and other protein hydrolysates and in the manuf. of cheese as a milk-clotting agent. Pepsin is an enzyme that is released by the chief cells in the stomach and that degrades food proteins into peptides. Pepsin was discovered in 1836 by Theodor Schwann who also coined this enzymes name from the Greek word pepsis, meaning digestion (peptein: to digest). It was the first animal enzyme to be discovered, and, in 1929, it became one of the first enzymes to be crystallized, by John H. Northrop. Pepsin is a digestive protease. P - Antiparasitic products, insecticides and repellents > P03 - Ectoparasiticides, incl. scabicides, insecticides and repellents > P03A - Ectoparasiticides, incl. scabicides > P03AB - Chlorine containing products A - Alimentary tract and metabolism > A09 - Digestives, incl. enzymes > A09A - Digestives, incl. enzymes > A09AA - Enzyme preparations It is used in the preparation of fish meal and other protein hydrolysates and in the manuf. of cheese as a milk-clotting agent

   

lindane

l-α-Hexachlorocyclohexane

C6H6Cl6 (287.8601)


P - Antiparasitic products, insecticides and repellents > P03 - Ectoparasiticides, incl. scabicides, insecticides and repellents > P03A - Ectoparasiticides, incl. scabicides > P03AB - Chlorine containing products A - Alimentary tract and metabolism > A09 - Digestives, incl. enzymes > A09A - Digestives, incl. enzymes > A09AA - Enzyme preparations

   

3-ketoadipate

3-Oxoadipic acid

C6H8O5 (160.0372)


An oxo dicarboxylic acid consisting of adipic acid having a single oxo group at the 3-position.

   

FA 6:3;O2

(2E,4Z)-4-hydroxy-6-oxohexa-2,4-dienoic acid

C6H6O4 (142.0266)


cis,cis-Muconic acid, a metabolic intermediate of Klebsiella pneumonia, can be converted to adipic acid and terephthalic acid, which are important monomers of synthetic polymers. cis,cis-Muconic acid is also a biochemical material that can be used for the production of various plastics and polymers and is particularly gaining attention as an adipic acid precursor for the synthesis of nylon-6,6[1][2].

   

γ-lindane

l-α-Hexachlorocyclohexane

C6H6Cl6 (287.8601)


P - Antiparasitic products, insecticides and repellents > P03 - Ectoparasiticides, incl. scabicides, insecticides and repellents > P03A - Ectoparasiticides, incl. scabicides > P03AB - Chlorine containing products A - Alimentary tract and metabolism > A09 - Digestives, incl. enzymes > A09A - Digestives, incl. enzymes > A09AA - Enzyme preparations

   

chlorohydroquinone

chlorohydroquinone

C6H5ClO2 (143.9978)


A benzenediol that consists of hydroquinone bearing a single chloro substituent.

   

4-Oxohex-2-enedioate

4-Oxohex-2-enedioate

C6H6O5 (158.0215)