Gene Association: PSMD5

UniProt Search: PSMD5 (PROTEIN_CODING)
Function Description: proteasome 26S subunit, non-ATPase 5

found 4 associated metabolites with current gene based on the text mining result from the pubmed database.

m-chlorophenylpiperazine (m-CPP)

1-(3-Chlorophenyl)piperazine monohydrochloride

C10H13ClN2 (196.0767)


m-chlorophenylpiperazine (m-CPP) is a metabolite of trazodone. Trazodone (also sold under the brand names Desyrel, Oleptro, Beneficat, Deprax, Desirel, Molipaxin, Thombran, Trazorel, Trialodine, Trittico, and Mesyrel) is an antidepressant of the serotonin antagonist and reuptake inhibitor (SARI) class. It is a phenylpiperazine compound. Trazodone also has anxiolytic and hypnotic effects. Trazodone has considerably fewer prominent anticholinergic and sexual side effects than most of the tricyclic antidepressants (TCAs). (Wikipedia) D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists CONFIDENCE Parent Substance with Reference Standard (Level 1); INTERNAL_ID 1300 EAWAG_UCHEM_ID 2818; CONFIDENCE standard compound CONFIDENCE standard compound; EAWAG_UCHEM_ID 2818

   

Oxamate

Oxalic monoamide

C2H3NO3 (89.0113)


KEIO_ID O011

   

OXAMIC ACID

OXAMIC ACID

C2H3NO3 (89.0113)


A dicarboxylic acid monoamide resulting from the formal condensation of one of the carboxy groups of oxalic acid with ammonia.

   

3-Chlorophenyl piperazine

1-(3-Chlorophenyl)piperazine

C10H13ClN2 (196.0767)


A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone. D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists