Gene Association: PYCR3

UniProt Search: PYCR3 (PROTEIN_CODING)
Function Description: pyrroline-5-carboxylate reductase 3

found 4 associated metabolites with current gene based on the text mining result from the pubmed database.

1-Pyrroline-2-carboxylic acid

3,4-dihydro-2H-pyrrol-1-ium-5-carboxylate

C5H7NO2 (113.0477)


1-Pyrroline-2-carboxylic acid is a terminal product of D-proline metabolism. Specifically D-proline is converted to 1-Pyrroline-2-carboxylic acid via D-amino acid oxidase. This spontaneously breaks down to 2-oxo-5-amino-valerate. [HMDB] 1-Pyrroline-2-carboxylic acid is a terminal product of D-proline metabolism. Specifically D-proline is converted to 1-Pyrroline-2-carboxylic acid via D-amino acid oxidase. This spontaneously breaks down to 2-oxo-5-amino-valerate.

   

Gamma-glutamyl-L-putrescine

(2S)-2-amino-4-[(4-aminobutyl)carbamoyl]butanoic acid

C9H19N3O3 (217.1426)


Gamma-glutamyl-L-putrescine is involved in the putrescine II degradation pathway. γ-glutamyl-L-putrescine reacts with H2O and O2 to produce γ-glutamyl-γ-aminobutyraldehyde, H2O2, and NH4+. γ-glutamyl-L-putrescine is formed from an ATP-driven reaction between putrescine, L-glutamate. Gamma-glutamyl-L-putrescine is involved in the putrescine II degradation pathway.

   

1-Pyrroline-2-carboxylic acid

3,4-Dihydro-2H-pyrrole-5-carboxylic acid

C5H7NO2 (113.0477)


The product resulting from formal oxidation of DL-proline by loss of hydrogen from the nitrogen and from the carbon alpha to the carboxylic acid, with the formation of a C=N bond.

   

gamma-L-Glutamylputrescine

gamma-L-Glutamylputrescine

C9H19N3O3 (217.1426)