Chemical Formula: C11H10O5

Chemical Formula C11H10O5

Found 85 metabolite its formula value is C11H10O5

Isofraxidin

7-Hydroxy-6,8-dimethoxy-2H-1-benzopyran-2-one

C11H10O5 (222.052821)


Isofraxidin, also known as 6,8-dimethoxy-7-hydroxycoumarin or 7-hydroxy-6,8-dimethoxy-2h-1-benzopyran-2-one, is a member of the class of compounds known as 7-hydroxycoumarins. 7-hydroxycoumarins are coumarins that contain one or more hydroxyl groups attached to the C7 position the coumarin skeleton. Isofraxidin is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Isofraxidin can be found in muskmelon, tarragon, and watermelon, which makes isofraxidin a potential biomarker for the consumption of these food products. Isofraxidin is a chemical compound found in a variety of plants including Eleutherococcus senticosus . Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2]. Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2].

   

Fraxidin

InChI=1/C11H10O5/c1-14-7-5-6-3-4-8(12)16-10(6)9(13)11(7)15-2/h3-5,13H,1-2H

C11H10O5 (222.052821)


Fraxidin is a hydroxycoumarin. Fraxidin is a natural product found in Artemisia minor, Melilotus messanensis, and other organisms with data available. CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2344 Fraxidin is a class of coumarin isolated from the roots of Jatropha podagrica, exhibits antibacterial activity against Bacillus subtilis with an inhibition zone of 12 mm at a concentration of 20 μg/disk[1][2]. Fraxidin is a class of coumarin isolated from the roots of Jatropha podagrica, exhibits antibacterial activity against Bacillus subtilis with an inhibition zone of 12 mm at a concentration of 20 μg/disk[1][2].

   

2-succinylbenzoate

4-(2-Carboxyphenyl)-4-oxobutyric acid

C11H10O5 (222.052821)


O-succinylbenzoate, also known as 4-(2-carboxyphenyl)-4-oxobutyric acid or 2-(3-carboxypropionyl)benzoic acid, is a member of the class of compounds known as alkyl-phenylketones. Alkyl-phenylketones are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group. O-succinylbenzoate is practically insoluble (in water) and a weakly acidic compound (based on its pKa). O-succinylbenzoate can be synthesized from benzoic acid. O-succinylbenzoate can also be synthesized into 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA. O-succinylbenzoate can be found in a number of food items such as nectarine, green bean, japanese persimmon, and rye, which makes O-succinylbenzoate a potential biomarker for the consumption of these food products. O-succinylbenzoate may be a unique E.coli metabolite.

   

Leptodactylone

8-hydroxy-5,7-dimethoxy-chromen-2-one

C11H10O5 (222.052821)


   

Sphagnum acid

p-hydroxy-beta-(carboxymethyl)-cinnamic acid

C11H10O5 (222.052821)


   

6-(2-Methoxyvinyl)benzo[1,3]dioxole-5-carboxylic acid

6-(2-Methoxyvinyl)benzo[1,3]dioxole-5-carboxylic acid

C11H10O5 (222.052821)


   

2-Hydroxy-7-hydroxymethylchromene-2-carboxylate

2-Hydroxy-7-hydroxymethylchromene-2-carboxylate

C11H10O5 (222.052821)


   

2-Hydroxy-4-hydroxymethylbenzalpyruvate

2-Hydroxy-4-hydroxymethylbenzalpyruvate

C11H10O5 (222.052821)


   

Isofraxidin

7-hydroxy-6,8-dimethoxy-chromen-2-one;Isofraxidin

C11H10O5 (222.052821)


Isofraxidin is a hydroxycoumarin. Isofraxidin is a natural product found in Artemisia alba, Artemisia assoana, and other organisms with data available. Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2]. Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2].

   

Tomentin[coumarin]

Tomentin[coumarin]

C11H10O5 (222.052821)


   

Fraxinol

6-hydroxy-5,7-dimethoxy-2H-chromen-2-one

C11H10O5 (222.052821)


Fraxinol is isolated from Lobelia chinensis[1]. Fraxinol is isolated from Lobelia chinensis[1].

   

Acetyl 2-acetyloxybenzoate

Acetyl 2-(acetyloxy)benzoic acid

C11H10O5 (222.052821)


   

p-Coumaroyl glycolic acid

2-{[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}acetic acid

C11H10O5 (222.052821)


P-coumaroyl glycolic acid is a member of the class of compounds known as coumaric acid esters. Coumaric acid esters are aromatic compounds containing an ester derivative of coumaric acid. P-coumaroyl glycolic acid is practically insoluble (in water) and a weakly acidic compound (based on its pKa). P-coumaroyl glycolic acid can be found in lentils, which makes P-coumaroyl glycolic acid a potential biomarker for the consumption of this food product.

   

Fraxinol

2H-1-Benzopyran-2-one, 6-hydroxy-5,7-dimethoxy-

C11H10O5 (222.052821)


Fraxinol is a member of the class of compounds known as hydroxycoumarins. Hydroxycoumarins are coumarins that contain one or more hydroxyl groups attached to the coumarin skeleton. Fraxinol is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Fraxinol can be found in sour cherry, which makes fraxinol a potential biomarker for the consumption of this food product. Fraxinol is a natural product found in Elsholtzia bodinieri, Prunus prostrata, and other organisms with data available. Fraxinol is isolated from Lobelia chinensis[1]. Fraxinol is isolated from Lobelia chinensis[1].

   
   

Ochratoxin beta, (+/-)-

Ochratoxin beta, (+/-)-

C11H10O5 (222.052821)


   

Umckalin

2H-1-Benzopyran-2-one, 7-hydroxy-5,6-dimethoxy-

C11H10O5 (222.052821)


Umckalin is a natural product found in Allamanda blanchetii, Diatenopteryx sorbifolia, and other organisms with data available.

   

7,8-Dimethoxy-6-hydroxycoumarin

7,8-Dimethoxy-6-hydroxycoumarin

C11H10O5 (222.052821)


   
   

Saikochromone A

Saikochromone A

C11H10O5 (222.052821)


   

6,8-dihydroxy-4-(1-hydroxyethyl)isochromen-1-one

6,8-dihydroxy-4-(1-hydroxyethyl)isochromen-1-one

C11H10O5 (222.052821)


   

6-formyl-5-hydroxy-7-methoxy-4-methylphthalide

6-formyl-5-hydroxy-7-methoxy-4-methylphthalide

C11H10O5 (222.052821)


   

Convolvulanic acid B

Convolvulanic acid B

C11H10O5 (222.052821)


   

3,4-dihydro-8-hydroxy-3-methyl-1 h -2-benzopyran-1-one-5-carboxylic acid

3,4-dihydro-8-hydroxy-3-methyl-1 h -2-benzopyran-1-one-5-carboxylic acid

C11H10O5 (222.052821)


   
   
   
   

Benzaldehyde, 2,4-bis(acetyloxy)-

Benzaldehyde, 2,4-bis(acetyloxy)-

C11H10O5 (222.052821)


   
   

Pisonin A

Pisonin A

C11H10O5 (222.052821)


A member of the class of chromones that is chromone substituted by a hydroxy group at position 5 and methoxy groups at positions 6 and 7 respectively. It has been isolated from Pisonia aculeata.

   

(E)-3-methoxy-2-[3,4-(methylenedioxy)phenyl]propenoic acid

(E)-3-methoxy-2-[3,4-(methylenedioxy)phenyl]propenoic acid

C11H10O5 (222.052821)


   

Rosellinic acid

Rosellinic acid

C11H10O5 (222.052821)


   

4-hydroxymethyl-5-(5-hydroxymethylfuran-2-ylmethylene)-5H-furan-2-one|ellipsoidone A

4-hydroxymethyl-5-(5-hydroxymethylfuran-2-ylmethylene)-5H-furan-2-one|ellipsoidone A

C11H10O5 (222.052821)


   

3,4-Diacetoxybenzaldehyde

3,4-Diacetoxybenzaldehyde

C11H10O5 (222.052821)


   

Arteminin

5-hydroxy-6,8-dimethoxychromen-2-one

C11H10O5 (222.052821)


Arteminin is a natural product found in Artemisia apiacea and Artemisia carvifolia with data available.

   
   

2,3-Diformyl-6-methoxy-5-methylbenzoic acid, 9CI

2,3-Diformyl-6-methoxy-5-methylbenzoic acid, 9CI

C11H10O5 (222.052821)


   

6-hydroxy-7,8-dimethoxycoumarin

6-hydroxy-7,8-dimethoxycoumarin

C11H10O5 (222.052821)


   

6-formyl-7-hydroxy-5-methoxy-4-methylphthalide

6-formyl-7-hydroxy-5-methoxy-4-methylphthalide

C11H10O5 (222.052821)


   
   
   
   
   

SCHEMBL16431771

SCHEMBL16431771

C11H10O5 (222.052821)


   

Pisonin B

Pisonin B

C11H10O5 (222.052821)


A member of the class of chromones that is chromone substituted by hydroxy groups at positions 5 and 7, a methoxy groups at position 6 and a methyl group at position 2. Isolated from Pisonia aculeata, it exhibits antitubercular activity.

   

6-hydroxy-3-hydroxymethyl-8-methoxyisocoumarin

6-hydroxy-3-hydroxymethyl-8-methoxyisocoumarin

C11H10O5 (222.052821)


   

Halenichlomone C

Halenichlomone C

C11H10O5 (222.052821)


   

methyl (3R)-3,4-dihydro-8-hydroxyisocoumarin-3-carboxylate|tenuissimasatin

methyl (3R)-3,4-dihydro-8-hydroxyisocoumarin-3-carboxylate|tenuissimasatin

C11H10O5 (222.052821)


   

polyporapyranone H

polyporapyranone H

C11H10O5 (222.052821)


   

MCULE-2063396728

MCULE-2063396728

C11H10O5 (222.052821)


   

Microsphaerophthalide B

Microsphaerophthalide B

C11H10O5 (222.052821)


   
   

6,7,9-Trihydroxy-3-methylcyclohepta[c]pyran-8(1H)-one

6,7,9-Trihydroxy-3-methylcyclohepta[c]pyran-8(1H)-one

C11H10O5 (222.052821)


   

7-hydroxy-6,8-dimethoxychromen-4-one

7-hydroxy-6,8-dimethoxychromen-4-one

C11H10O5 (222.052821)


   

(Z)-2-<(4-hydroxyphenyl)methyl>but-2-enedioic acid

(Z)-2-<(4-hydroxyphenyl)methyl>but-2-enedioic acid

C11H10O5 (222.052821)


   

5-hydroxy-7,8-dimethoxycoumarin

5-hydroxy-7,8-dimethoxycoumarin

C11H10O5 (222.052821)


   

Tomentin

5-HYDROXY-6,7-DIMETHOXYCHROMEN-2-ONE

C11H10O5 (222.052821)


5-Hydroxy-6,7-dimethoxychromen-2-one is a natural product found in Artemisia capillaris, Artemisia annua, and Artemisia monosperma with data available.

   

Isofraxidin

Isofraxidin

C11H10O5 (222.052821)


Annotation level-1 Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2]. Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2].

   

7-hydroxy-6,8-dimethoxychromen-2-one

NCGC00385522-01!7-hydroxy-6,8-dimethoxychromen-2-one

C11H10O5 (222.052821)


   

8-hydroxy-3-methyl-1-oxo-3,4-dihydroisochromene-5-carboxylic acid

NCGC00386094-01!8-hydroxy-3-methyl-1-oxo-3,4-dihydroisochromene-5-carboxylic acid

C11H10O5 (222.052821)


   

6,8-dihydroxy-7-methoxy-3-methylisochromen-1-one

NCGC00381372-01!6,8-dihydroxy-7-methoxy-3-methylisochromen-1-one

C11H10O5 (222.052821)


   

8-hydroxy-6,7-dimethoxychromen-2-one

NCGC00384767-01!8-hydroxy-6,7-dimethoxychromen-2-one

C11H10O5 (222.052821)


   

Fraxidin

InChI=1/C11H10O5/c1-14-7-5-6-3-4-8(12)16-10(6)9(13)11(7)15-2/h3-5,13H,1-2H

C11H10O5 (222.052821)


Fraxidin is a hydroxycoumarin. Fraxidin is a natural product found in Artemisia minor, Melilotus messanensis, and other organisms with data available. Fraxidin, also known as 8-hydroxy-6,7-dimethoxy-2h-1-benzopyran-2-one, is a member of the class of compounds known as hydroxycoumarins. Hydroxycoumarins are coumarins that contain one or more hydroxyl groups attached to the coumarin skeleton. Fraxidin is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Fraxidin can be found in durian and watermelon, which makes fraxidin a potential biomarker for the consumption of these food products. Fraxidin is a class of coumarin isolated from the roots of Jatropha podagrica, exhibits antibacterial activity against Bacillus subtilis with an inhibition zone of 12 mm at a concentration of 20 μg/disk[1][2]. Fraxidin is a class of coumarin isolated from the roots of Jatropha podagrica, exhibits antibacterial activity against Bacillus subtilis with an inhibition zone of 12 mm at a concentration of 20 μg/disk[1][2]. Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2]. Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2].

   

ETHYL 3,4-METHYLENEDIOXYBENZOYLFORMATE

ETHYL 3,4-METHYLENEDIOXYBENZOYLFORMATE

C11H10O5 (222.052821)


   

4-(3-Methoxy-phenyl)-2,4-dioxo-butyric acid

4-(3-Methoxy-phenyl)-2,4-dioxo-butyric acid

C11H10O5 (222.052821)


   

ethyl 5-formyl-1,3-benzodioxole-4-carboxylate

ethyl 5-formyl-1,3-benzodioxole-4-carboxylate

C11H10O5 (222.052821)


   

4-(4-Methoxy-phenyl)-2,4-dioxo-butyric acid

4-(4-Methoxy-phenyl)-2,4-dioxo-butyric acid

C11H10O5 (222.052821)


   

5,6-dimethoxy-1-benzofuran-2-carboxylic acid

5,6-dimethoxy-1-benzofuran-2-carboxylic acid

C11H10O5 (222.052821)


   

4-(2-Methoxy-phenyl)-2,4-dioxo-butyric acid

4-(2-Methoxy-phenyl)-2,4-dioxo-butyric acid

C11H10O5 (222.052821)


   

Methyl 3-(1,3-benzodioxol-5-yl)-2-oxiranecarboxylate

Methyl 3-(1,3-benzodioxol-5-yl)-2-oxiranecarboxylate

C11H10O5 (222.052821)


   

Benzoic acid,2,3-diformyl-6-methoxy-5-methyl-

Benzoic acid,2,3-diformyl-6-methoxy-5-methyl-

C11H10O5 (222.052821)


   

3,4-Dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-carboxylic acid

3,4-Dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-carboxylic acid

C11H10O5 (222.052821)


   

8-Hydroxy-3-methyl-1-oxo-3,4-dihydroisochromene-5-carboxylic acid

8-Hydroxy-3-methyl-1-oxo-3,4-dihydroisochromene-5-carboxylic acid

C11H10O5 (222.052821)


   

7-Oxocyclohepta-1,3,5-triene-1,4-diyl diacetate

7-Oxocyclohepta-1,3,5-triene-1,4-diyl diacetate

C11H10O5 (222.052821)


   

2,4-Diacetoxytropone

2,4-Diacetoxytropone

C11H10O5 (222.052821)


   

Phytodolor

2H-1- Benzopyran-2-one, 7-hydroxy-6,8-dimethoxy-

C11H10O5 (222.052821)


Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2]. Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2].

   

2-Benzyl-3-oxobutanedioic acid

2-Benzyl-3-oxobutanedioic acid

C11H10O5 (222.052821)


   

5-Formyl-3-methoxy-4-hydroxybenzeneacrylic acid

5-Formyl-3-methoxy-4-hydroxybenzeneacrylic acid

C11H10O5 (222.052821)


   

2-Hydroxy-4-hydroxymethylbenzalpyruvate

2-Hydroxy-4-hydroxymethylbenzalpyruvate

C11H10O5 (222.052821)


   

2-Hydroxy-4-hydroxymethylbenzylidenepyruvic acid

2-Hydroxy-4-hydroxymethylbenzylidenepyruvic acid

C11H10O5 (222.052821)


   

(E)-3-(6-hydroxy-7-methoxy-1,3-benzodioxol-5-yl)prop-2-enal

(E)-3-(6-hydroxy-7-methoxy-1,3-benzodioxol-5-yl)prop-2-enal

C11H10O5 (222.052821)


   

(E)-3-(7-hydroxy-6-methoxy-1,3-benzodioxol-5-yl)prop-2-enal

(E)-3-(7-hydroxy-6-methoxy-1,3-benzodioxol-5-yl)prop-2-enal

C11H10O5 (222.052821)


   

4,6-Diformyl-2,5-dimethoxytropone

4,6-Diformyl-2,5-dimethoxytropone

C11H10O5 (222.052821)


   

2-Acetoxy-2-methyl-5H-cyclohepta-1,3-dioxol-5-one

2-Acetoxy-2-methyl-5H-cyclohepta-1,3-dioxol-5-one

C11H10O5 (222.052821)


   

2-succinylbenzoate

o-Succinylbenzoic acid

C11H10O5 (222.052821)