Gene Association: SH2B3

UniProt Search: SH2B3 (PROTEIN_CODING)
Function Description: SH2B adaptor protein 3

found 2 associated metabolites with current gene based on the text mining result from the pubmed database.

Pipobroman

3-bromo-1-[4-(3-bromopropanoyl)piperazin-1-yl]propan-1-one

C10H16Br2N2O2 (353.9578)


Pipobroman is only found in individuals that have used or taken this drug. It is an antineoplastic agent that acts by alkylation. [PubChem]The mechanism of action is uncertain but pipobroman is thought to alkylate DNA leading to disruption of DNA synthesis and eventual cell death. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D009676 - Noxae > D000477 - Alkylating Agents D000970 - Antineoplastic Agents

   

pipobroman

pipobroman

C10H16Br2N2O2 (353.9578)


L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D009676 - Noxae > D000477 - Alkylating Agents D000970 - Antineoplastic Agents