Gene Association: NUMA1

UniProt Search: NUMA1 (PROTEIN_CODING)
Function Description: nuclear mitotic apparatus protein 1

found 3 associated metabolites with current gene based on the text mining result from the pubmed database.

(S)-scoulerine

(13aS)-5,8,13,13a-Tetrahydro-3,10-dimethoxy-6H- dibenzo[a,g]quinolizine-2,9-diol

C19H21NO4 (327.1471)


(s)-scoulerine, also known as discretamine or aequaline, belongs to protoberberine alkaloids and derivatives class of compounds. Those are alkaloids with a structure based on a protoberberine moiety, which consists of a 5,6-dihydrodibenzene moiety fused to a quinolizinium and forming 5,6-Dihydrodibenzo(a,g)quinolizinium skeleton (s)-scoulerine is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). (s)-scoulerine can be found in a number of food items such as rice, lemon grass, chinese bayberry, and sea-buckthornberry, which makes (s)-scoulerine a potential biomarker for the consumption of these food products.

   

Scoulerine

6H-Dibenzo[a,g]quinolizine-2,9-diol, 5,8,13,13a-tetrahydro-3,10-dimethoxy-, (.+/-.)-

C19H21NO4 (327.1471)


(R,S)-Scoulerine is an alkaloid. Scoulerine is a natural product found in Sarcocapnos saetabensis, Corydalis bungeana, and other organisms with data available.

   

Scoulerin

(13aS)-3,10-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,9-diol

C19H21NO4 (327.1471)


A berberine alkaloid isolated from Corydalis saxicola.