Gene Association: DNAJA1

UniProt Search: DNAJA1 (PROTEIN_CODING)
Function Description: DnaJ heat shock protein family (Hsp40) member A1

found 6 associated metabolites with current gene based on the text mining result from the pubmed database.

Mevalonic acid-5P

(3R)-3-Hydroxy-3-methyl-5-(phosphonooxy)pentanoic acid

C6H13O7P (228.0399)


Mevalonic acid-5p, also known as (R)-5-phosphomevalonate or mevalonate-5p, is a member of the class of compounds known as monoalkyl phosphates. Monoalkyl phosphates are organic compounds containing a phosphate group that is linked to exactly one alkyl chain. Thus, mevalonic acid-5p is considered to be a fatty acid lipid molecule. Mevalonic acid-5p is soluble (in water) and a moderately acidic compound (based on its pKa). Mevalonic acid-5p can be found in a number of food items such as rowanberry, common oregano, caraway, and cherry tomato, which makes mevalonic acid-5p a potential biomarker for the consumption of these food products. Mevalonic acid-5p can be found primarily throughout most human tissues. Mevalonic acid-5p exists in all eukaryotes, ranging from yeast to humans. In humans, mevalonic acid-5p is involved in several metabolic pathways, some of which include pamidronate action pathway, rosuvastatin action pathway, pravastatin action pathway, and lovastatin action pathway. Mevalonic acid-5p is also involved in several metabolic disorders, some of which include hypercholesterolemia, lysosomal acid lipase deficiency (wolman disease), hyper-igd syndrome, and mevalonic aciduria. Mevalonic acid-5P (CAS: 1189-94-2), also known as 5-phosphomevalonic acid, belongs to the class of organic compounds known as monoalkyl phosphates. These are organic compounds containing a phosphate group that is linked to exactly one alkyl chain. Within humans, mevalonic acid-5P participates in many enzymatic reactions. In particular, mevalonic acid-5P can be biosynthesized from mevalonate; which is mediated by the enzyme mevalonate kinase. In addition, mevalonic acid-5P can be converted into mevalonic acid-5-pyrophosphate through its interaction with the enzyme phosphomevalonate kinase. In humans, mevalonic acid-5P is involved in the mevalonate pathway. Outside of the human body, mevalonic acid-5P has been detected, but not quantified in, several different foods, such as oriental wheat, devilfish, pepper (spice), redcurrants, and star fruits. This could make mevalonic acid-5P a potential biomarker for the consumption of these foods.

   

Cyhalothrin

Cyclopropanecarboxylicacid, 3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethyl-,(S)-cyano(3-phenoxyphenyl)methyl ester, (1R,3R)-

C23H19ClF3NO3 (449.1005)


D010575 - Pesticides > D007306 - Insecticides > D011722 - Pyrethrins D016573 - Agrochemicals Same as: D07762

   

2-Chlorobiphenyl

1-Chloro-2-phenylbenzene

C12H9Cl (188.0393)


   

pcb 1

2-Monochlorobiphenyl

C12H9Cl (188.0393)


   

(3R)-3-Hydroxy-3-methyl-5-(phosphonooxy)pentanoic acid

(3R)-3-Hydroxy-3-methyl-5-(phosphonooxy)pentanoic acid

C6H13O7P (228.0399)


   

λ-Cyhalothrin

Cyclopropanecarboxylicacid, 3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethyl-,(S)-cyano(3-phenoxyphenyl)methyl ester, (1R,3R)-

C23H19ClF3NO3 (449.1005)


D010575 - Pesticides > D007306 - Insecticides > D011722 - Pyrethrins D016573 - Agrochemicals