UDP-4-dehydro-6-deoxy-D-glucose (BioDeep_00000005404)

 

Secondary id: BioDeep_00001870059

human metabolite Endogenous


代谢物信息卡片


{[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-hydroxy-2-oxo-1,2-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}[({[(2R,3R,4R,6R)-3,4-dihydroxy-6-methyl-5-oxooxan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphinic acid

化学式: C15H22N2O16P2 (548.0444552)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 2.98%

分子结构信息

SMILES: CC1C(=O)C(C(C(O1)OP(=O)(O)OP(=O)(O)OCC2C(C(C(O2)N3C=CC(=O)NC3=O)O)O)O)O
InChI: InChI=1S/C15H22N2O16P2/c1-5-8(19)10(21)12(23)14(30-5)32-35(27,28)33-34(25,26)29-4-6-9(20)11(22)13(31-6)17-3-2-7(18)16-15(17)24/h2-3,5-6,9-14,20-23H,4H2,1H3,(H,25,26)(H,27,28)(H,16,18,24)/t5-,6-,9-,10+,11-,12-,13-,14+/m1/s1

描述信息

UDP-4-dehydro-6-deoxy-D-glucose, also known as UDP-4-keto-6-deoxy-D-glucose, belongs to the class of organic compounds known as pyrimidine nucleotide sugars. These are pyrimidine nucleotides bound to a saccharide derivative through the terminal phosphate group. UDP-4-dehydro-6-deoxy-D-glucose is an extremely weak basic (essentially neutral) compound (based on its pKa). Outside of the human body, UDP-4-dehydro-6-deoxy-D-glucose has been detected, but not quantified in, several different foods, such as Oregon yampahs, oriental wheat, Chinese mustards, blackcurrants, and pomegranates. This could make UDP-4-dehydro-6-deoxy-D-glucose a potential biomarker for the consumption of these foods. UDP-4-dehydro-6-deoxy-D-glucose is synthesized from UDP-glucose via the enzyme UDP-glucose 4,6-dehydratase.
UDP-4-dehydro-6-deoxy-D-glucose is synthesized from UDP-glucose through the enzyme UDP-glucose 4,6-dehydratase. [HMDB]. UDP-4-dehydro-6-deoxy-D-glucose is found in many foods, some of which are alaska wild rhubarb, soy bean, ginkgo nuts, and common beet.

同义名列表

14 个代谢物同义名

{[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-hydroxy-2-oxo-1,2-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}[({[(2R,3R,4R,6R)-3,4-dihydroxy-6-methyl-5-oxooxan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphinic acid; [(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-hydroxy-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy({[(2R,3R,4R,6R)-3,4-dihydroxy-6-methyl-5-oxooxan-2-yl]oxy(hydroxy)phosphoryl}oxy)phosphinic acid; UDP-4-Dehydro-6-deoxy-alpha-D-glucose; UDP-4-Keto-6-deoxy-alpha-D-glucose; UDP-4-Dehydro-6-deoxy-a-D-glucose; UDP-4-Dehydro-6-deoxy-α-D-glucose; UDP-4-oxo-6-Deoxy-alpha-D-glucose; UDP-4-dehydro-6-deoxy-D-glucose; UDP-4-Keto-6-deoxy-α-D-glucose; UDP-4-oxo-6-Deoxy-α-D-glucose; UDP-4-Keto-6-deoxy-D-glucose; UDP-4-oxo-6-Deoxy-D-glucose; UDP-4-keto-6-deoxyglucose; UDP 4-Keto-6-deoxyglucose



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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INOH(0)

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2 个相关的物种来源信息

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  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
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  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Liang Ma, Omar Salas, Kyle Bowler, Maor Bar-Peled, Amir Sharon. UDP-4-Keto-6-Deoxyglucose, a Transient Antifungal Metabolite, Weakens the Fungal Cell Wall Partly by Inhibition of UDP-Galactopyranose Mutase. mBio. 2017 11; 8(6):. doi: 10.1128/mbio.01559-17. [PMID: 29162710]
  • Viviana Martinez, Miles Ingwers, James Smith, John Glushka, Ting Yang, Maor Bar-Peled. Biosynthesis of UDP-4-keto-6-deoxyglucose and UDP-rhamnose in pathogenic fungi Magnaporthe grisea and Botryotinia fuckeliana. The Journal of biological chemistry. 2012 Jan; 287(2):879-92. doi: 10.1074/jbc.m111.287367. [PMID: 22102281]