Leucyl-leucine (BioDeep_00000004072)

 

Secondary id: BioDeep_00000180442, BioDeep_00000897215, BioDeep_00000897326, BioDeep_00001878053

human metabolite Endogenous


代谢物信息卡片


(2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanoic acid

化学式: C12H24N2O3 (244.1787)
中文名称: L-亮氨酸二肽
谱图信息: 最多检出来源 Homo sapiens(feces) 10.31%

Reviewed

Last reviewed on 2024-09-13.

Cite this Page

Leucyl-leucine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/leucyl-leucine (retrieved 2025-03-11) (BioDeep RN: BioDeep_00000004072). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC(C)CC(C(=O)NC(CC(C)C)C(=O)O)N
InChI: InChI=1S/C12H24N2O3/c1-7(2)5-9(13)11(15)14-10(12(16)17)6-8(3)4/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)

描述信息

Leucylleucine is a dipeptide composed of two leucine residues. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signalling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.
Leu-Leu-OH, a Leu derivative, is a dipeptide.

同义名列表

24 个代谢物同义名

(2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanoic acid; Leucylleucine monohydrochloride, (L-leu-L-leu)-isomer; Leucylleucine, (L-leu-D-leu)-isomer; Leucylleucine, (D-leu-D-leu)-isomer; Leucylleucine, (L-leu-L-leu)-isomer; Leucine leucine dipeptide; Leucine-leucine dipeptide; N-L-Leucinyl-L-leucine; N-L-Leucyl-L-leucine; L-Leucinyl-L-leucine; L-Leucyl-L-leucine; N-Leucinylleucine; Leucinyl-leucine; H-L-Leu-L-leu-OH; N-Leucylleucine; Leucyl-leucine; Leucylleucine; L-L Dipeptide; LL Dipeptide; H-Leu-leu-OH; L-Leu-L-leu; Leu-leu; LL; Leu-Leu-OH



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Amanda J Cross, Steven C Moore, Simina Boca, Wen-Yi Huang, Xiaoqin Xiong, Rachael Stolzenberg-Solomon, Rashmi Sinha, Joshua N Sampson. A prospective study of serum metabolites and colorectal cancer risk. Cancer. 2014 Oct; 120(19):3049-57. doi: 10.1002/cncr.28799. [PMID: 24894841]
  • Li Zheng, Cosmo A Saunders, Erika B Sorensen, Nicole C Waxmonsky, Sean D Conner. Notch signaling from the endosome requires a conserved dileucine motif. Molecular biology of the cell. 2013 Feb; 24(3):297-307. doi: 10.1091/mbc.e12-02-0081. [PMID: 23171551]
  • Ya-Yun Wang, Yi-Fang Tsay. Arabidopsis nitrate transporter NRT1.9 is important in phloem nitrate transport. The Plant cell. 2011 May; 23(5):1945-57. doi: 10.1105/tpc.111.083618. [PMID: 21571952]
  • Griet Van Zeebroeck, Beatriz Monge Bonini, Matthias Versele, Johan M Thevelein. Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor. Nature chemical biology. 2009 Jan; 5(1):45-52. doi: 10.1038/nchembio.132. [PMID: 19060912]
  • Chanyarat Paungfoo-Lonhienne, Peer M Schenk, Thierry G A Lonhienne, Richard Brackin, Stefan Meier, Doris Rentsch, Susanne Schmidt. Nitrogen affects cluster root formation and expression of putative peptide transporters. Journal of experimental botany. 2009; 60(9):2665-76. doi: 10.1093/jxb/erp111. [PMID: 19380419]
  • John S Ramsey, Alex C C Wilson, Martin de Vos, Qi Sun, Cecilia Tamborindeguy, Agnese Winfield, Gaynor Malloch, Dawn M Smith, Brian Fenton, Stewart M Gray, Georg Jander. Genomic resources for Myzus persicae: EST sequencing, SNP identification, and microarray design. BMC genomics. 2007 Nov; 8(?):423. doi: 10.1186/1471-2164-8-423. [PMID: 18021414]
  • Lesley Colgan, Hao Liu, Steven Y Huang, Yong-Jian Liu. Dileucine motif is sufficient for internalization and synaptic vesicle targeting of vesicular acetylcholine transporter. Traffic (Copenhagen, Denmark). 2007 May; 8(5):512-22. doi: 10.1111/j.1600-0854.2007.00555.x. [PMID: 17451554]
  • J A Vizcaíno, R E Cardoza, M Hauser, R Hermosa, M Rey, A Llobell, J M Becker, S Gutiérrez, E Monte. ThPTR2, a di/tri-peptide transporter gene from Trichoderma harzianum. Fungal genetics and biology : FG & B. 2006 Apr; 43(4):234-46. doi: 10.1016/j.fgb.2005.12.003. [PMID: 16466953]
  • Y Ito, Y Watanabe, K Hirano, M Sugiura, S Sawaki, T Ogiso. A fluorometric method for dipeptidase activity measurement in urine, using L-alanyl-L-alanine as substrate. Journal of biochemistry. 1984 Jul; 96(1):1-8. doi: 10.1093/oxfordjournals.jbchem.a134801. [PMID: 6436229]