Gene Association: NARS1

UniProt Search: NARS1 (PROTEIN_CODING)
Function Description: asparaginyl-tRNA synthetase 1

found 4 associated metabolites with current gene based on the text mining result from the pubmed database.

Etomidate

(R)-(+)-1-(alpha-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester

Etomidate is only found in individuals that have used or taken this drug. It is an midazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic. [PubChem]Etomidate binds at a distinct binding site associated with a Cl^- ionopore at the GABA_A receptor, increasing the duration of time for which the Cl^- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged. D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics N - Nervous system > N01 - Anesthetics > N01A - Anesthetics, general C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent

threo-b-methylaspartate

DL-threo-beta-Methylaspartic acid

C5H9NO4 (147.0532)

Acquisition and generation of the data is financially supported in part by CREST/JST. KEIO_ID M009

Hydroxylated lecithin

(2S)-2-amino-3-(hydroxycarbamoyl)propanoic acid

C4H8N2O4 (148.0484)

Hydroxylated lecithin is used as a food additive [EAFUS] ("EAFUS: Everything Added to Food in the United States. [http://www.eafus.com/]") D000890 - Anti-Infective Agents > D000998 - Antiviral Agents D000970 - Antineoplastic Agents

Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate

C14H16N2O2 (244.1212)