Palmitic acid (BioDeep_00000000476)

 

Secondary id: BioDeep_00000229690, BioDeep_00000264842, BioDeep_00000859352

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite PANOMIX LipidSearch BioNovoGene_Lab2019 Volatile Flavor Compounds natural product


代谢物信息卡片


hexadecanoic acid

化学式: C16H32O2 (256.2402172)
中文名称: 软脂酸, 棕榈酸, 十六烷酸, 软脂酸; 棕榈酸，十六(烷)酸, 正十六烷酸
谱图信息: 最多检出来源 Homo sapiens(feces) 0.09%

Reviewed

Last reviewed on 2024-07-01.

Cite this Page

Palmitic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/palmitic_acid (retrieved 2024-11-21) (BioDeep RN: BioDeep_00000000476). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CCCCCCCCCCCCCCCC(=O)O
InChI: InChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)

描述信息

Palmitic acid, also known as palmitate or hexadecanoic acid, is a member of the class of compounds known as long-chain fatty acids. Long-chain fatty acids are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms. Thus, palmitic acid is considered to be a fatty acid lipid molecule. Palmitic acid is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Palmitic acid can be found in a number of food items such as sacred lotus, spinach, shallot, and corn salad, which makes palmitic acid a potential biomarker for the consumption of these food products. Palmitic acid can be found primarily in most biofluids, including feces, sweat, cerebrospinal fluid (CSF), and urine, as well as throughout most human tissues. Palmitic acid exists in all living species, ranging from bacteria to humans. In humans, palmitic acid is involved in several metabolic pathways, some of which include alendronate action pathway, rosuvastatin action pathway, simvastatin action pathway, and cerivastatin action pathway. Palmitic acid is also involved in several metabolic disorders, some of which include hypercholesterolemia, familial lipoprotein lipase deficiency, ethylmalonic encephalopathy, and carnitine palmitoyl transferase deficiency (I). Moreover, palmitic acid is found to be associated with schizophrenia. Palmitic acid is a non-carcinogenic (not listed by IARC) potentially toxic compound. Palmitic acid, or hexadecanoic acid in IUPAC nomenclature, is the most common saturated fatty acid found in animals, plants and microorganisms. Its chemical formula is CH3(CH2)14COOH, and its C:D is 16:0. As its name indicates, it is a major component of the oil from the fruit of oil palms (palm oil). Palmitic acid can also be found in meats, cheeses, butter, and dairy products. Palmitate is the salts and esters of palmitic acid. The palmitate anion is the observed form of palmitic acid at physiologic pH (7.4) . Palmitic acid is the first fatty acid produced during lipogenesis (fatty acid synthesis) and from which longer fatty acids can be produced. Palmitate negatively feeds back on acetyl-CoA carboxylase (ACC) which is responsible for converting acetyl-ACP to malonyl-ACP on the growing acyl chain, thus preventing further palmitate generation (DrugBank).
Palmitic acid, or hexadecanoic acid, is one of the most common saturated fatty acids found in animals, plants, and microorganisms. As its name indicates, it is a major component of the oil from the fruit of oil palms (palm oil). Excess carbohydrates in the body are converted to palmitic acid. Palmitic acid is the first fatty acid produced during fatty acid synthesis and is the precursor to longer fatty acids. As a consequence, palmitic acid is a major body component of animals. In humans, one analysis found it to make up 21–30\\\% (molar) of human depot fat (PMID: 13756126), and it is a major, but highly variable, lipid component of human breast milk (PMID: 352132). Palmitic acid is used to produce soaps, cosmetics, and industrial mould release agents. These applications use sodium palmitate, which is commonly obtained by saponification of palm oil. To this end, palm oil, rendered from palm tree (species Elaeis guineensis), is treated with sodium hydroxide (in the form of caustic soda or lye), which causes hydrolysis of the ester groups, yielding glycerol and sodium palmitate. Aluminium salts of palmitic acid and naphthenic acid were combined during World War II to produce napalm. The word "napalm" is derived from the words naphthenic acid and palmitic acid (Wikipedia). Palmitic acid is also used in the determination of water hardness and is a surfactant of Levovist, an intravenous ultrasonic contrast agent.
Hexadecanoic acid is a straight-chain, sixteen-carbon, saturated long-chain fatty acid. It has a role as an EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor, a plant metabolite, a Daphnia magna metabolite and an algal metabolite. It is a long-chain fatty acid and a straight-chain saturated fatty acid. It is a conjugate acid of a hexadecanoate.
A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
Palmitic acid is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Palmitic Acid is a saturated long-chain fatty acid with a 16-carbon backbone. Palmitic acid is found naturally in palm oil and palm kernel oil, as well as in butter, cheese, milk and meat.
Palmitic acid, or hexadecanoic acid is one of the most common saturated fatty acids found in animals and plants, a saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids. It occurs in the form of esters (glycerides) in oils and fats of vegetable and animal origin and is usually obtained from palm oil, which is widely distributed in plants. Palmitic acid is used in determination of water hardness and is an active ingredient of *Levovist*TM, used in echo enhancement in sonographic Doppler B-mode imaging and as an ultrasound contrast medium.
A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
A straight-chain, sixteen-carbon, saturated long-chain fatty acid.

Palmitic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=57-10-3 (retrieved 2024-07-01) (CAS RN: 57-10-3). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

同义名列表

148 个代谢物同义名

Palmitic acid, Pharmaceutical Secondary Standard; Certified Reference Material; Palmitic acid, United States Pharmacopeia (USP) Reference Standard; Palmitic acid, European Pharmacopoeia (EP) Reference Standard; Palmitic acid, certified reference material, TraceCERT(R); PALMITIC ACID (CONSTITUENT OF EVENING PRIMROSE OIL); PALMITIC ACID (CONSTITUENT OF SAW PALMETTO) [DSC]; PALMITIC ACID (CONSTITUENT OF SPIRULINA) [DSC]; PALMITIC ACID (CONSTITUENT OF BORAGE SEED OIL); Hexadecanoic acid 10 microg/mL in Acetonitrile; Palmitic acid, >=98\\% palmitic acid basis (GC); 4-02-00-01157 (Beilstein Handbook Reference); PALMITIC ACID (CONSTITUENT OF FLAX SEED OIL); Palmitic acid, Vetec(TM) reagent grade, 98\\%; PALMITIC ACID (CONSTITUENT OF SAW PALMETTO); PALMITIC ACID (CONSTITUENT OF SPIRULINA); Palmitic acid, SAJ first grade, >=95.0\\%; Palmitic acid, for synthesis, 98.0\\%; BA71C79B-C9B1-451A-A5BE-B480B5CC7D0C; LUCINACTANT COMPONENT PALMITIC ACID; Palmitic acid, purum, >=98.0\\% (GC); Palmitic acid, analytical standard; SURFAXIN COMPONENT PALMITIC ACID; Palmitic acid, natural, 98\\%, FG; HEXADECANOIC-11,11,12,12-D4 ACID; Palmitic acid; Hexadecanoic acid; Hexadecanoic acid Palmitic acid; Palmitic acid, >=95\\%, FCC, FG; Palmitic acid, BioXtra, >=99\\%; Palmitic acid, Grade II, ~95\\%; 1-Pentadecanecarboxylic acid; PALMITIC ACID [EP MONOGRAPH]; PALMITIC ACID (EP MONOGRAPH); (1(1)(3)C)hexadecanoic acid; Pentadecanecarboxylic acid; 1-Pentadecanecarboxylate; Palmitic acid (natural); Hexadecanoic acid (9CI); Palmitic acid (7CI,8CI); Hexadecanoate (n-C16:0); Palmitic acid [USAN:NF]; Hexadecanoic acid anion; PALMITIC ACID [WHO-DD]; PALMITIC ACID [USP-RS]; pentadecanecarboxylate; Hexadecanoic--d5 Acid; PALMITIC ACID [VANDF]; PALMITIC ACID (MART.); PALMITIC ACID [MART.]; Palmitic acid, >=99\\%; PALMITIC ACID [USAN]; PALMITIC ACID [INCI]; 1-Hexyldecanoic Acid; PALMITIC ACID [HSDB]; Palmitic acid_RaGuSa; PALMITIC ACID [FHFI]; Palmitic acid, pure; n-Hexadecanoic acid; n-Hexadecyclic Acid; PALMITIC ACID [FCC]; PALMITIC ACID [DSC]; Palmitic acid_jeyam; PALMITIC ACID [MI]; Palmitate, Calcium; CETYL ACID [VANDF]; Palmitic acid 95\\%; Palmitic Acid, FCC; PALMITIC ACID [II]; Palmitic acid (NF); EDENOR C 16-98-100; Acid, Hexadecanoic; Hydrofol acid 1690; PALMITIC ACID (II); Hexadecanoic acid; n-Hexadecoic acid; Palmitate, Sodium; Calcium Palmitate; Sodium Palmitate; Hexadecanoicacid; CH3-(CH2)14-COOH; hexaectylic acid; 1-hexyldecanoate; CH3-[CH2]14-COOH; Hexadecylic acid; Palmitinic acid; Industrene 4516; UNII-2V16EO95H1; hexadecoic acid; fatty acid 16:0; N-Hexadecanoate; Pristerene 4934; Tox21_112105_1; palmitoic acid; C16 Fatty acid; Palmitinsaeure; Acid, Palmitic; palmitic-acid; Aethalic acid; Palmitinsaure; n-hexadecoate; Hystrene 8016; Hystrene 9016; Palmitic Acid; Kortacid 1698; Hexadecanoate; Loxiol ep 278; Tox21_201671; Lunac P 95KC; Cetylic acid; Hexaectylate; Tox21_302966; Tox21_112105; Hexadecylate; Prifrac 2960; Prifac 2960; Emersol 143; CAS-57-10-3; Univol u332; Hexadecoate; Emersol 140; palmic acid; Glycon P-45; Palmitinate; 2V16EO95H1; palmitoate; Lunac P 95; Cetyl acid; Edenor C16; Lunac P 98; WLN: QV15; palmitate; AI3-01594; Hydrofol; Cetylate; FA(16:0); FA 16:0; 16:00; C16:0; 2hmb; 3v2q; 2hnx; 1b56; FAT; PAM; C16; PLM; Palmitic acid; Hexadecanoic acid; n-Hexadecanoic acid



数据库引用编号

36 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(18)

BioCyc(0)

PlantCyc(0)

代谢反应

1213 个相关的代谢反应过程信息。

Reactome(343)

BioCyc(0)

WikiPathways(7)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(863)

PharmGKB(0)

2356 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lisa Morisseau, Fumiya Tokito, Mathilde Lucas, Stéphane Poulain, Soo Hyeon Kim, Valérie Plaisance, Valérie Pawlowski, Cécile Legallais, Rachid Jellali, Yasuyuki Sakai, Amar Abderrahmani, Eric Leclerc. Transcriptomic profiling analysis of the effect of palmitic acid on 3D spheroids of β-like cells derived from induced pluripotent stem cells. Gene. 2024 Jul; 917(?):148441. doi: 10.1016/j.gene.2024.148441. [PMID: 38608795]
  • Louyin Ji, Hui Han, Xiaoli Shan, Pei Zhao, Huihua Chen, Chen Zhang, Ming Xu, Rong Lu, Wei Guo. Ginsenoside Rb1 ameliorates lipotoxicity-induced myocardial injury in diabetes mellitus by regulating Mfn2. European journal of pharmacology. 2024 Jul; 974(?):176609. doi: 10.1016/j.ejphar.2024.176609. [PMID: 38677536]
  • Danyang Liu, Tao Wang, Xingqi Zhao, Juan Chen, Tianqi Yang, Yi Shen, Yu-Dong Zhou. Saturated fatty acids stimulate cytokine production in tanycytes via the PP2Ac-dependent signaling pathway. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2024 Jun; 44(6):985-999. doi: 10.1177/0271678x231219115. [PMID: 38069840]
  • Yunping Yao, Zhiyuan Qiang, Meng Zhang, Jia Lin, Changmo Li. Thermal oxidation mechanism of palmitic aicd. Food research international (Ottawa, Ont.). 2024 Jun; 186(?):114372. doi: 10.1016/j.foodres.2024.114372. [PMID: 38729730]
  • Lingming Chen, Shuai Liu, Yunting Zhang, Qiling Tang, Chunyu Quan, Jundan Wang, Xinsheng Peng, Xiaofang Zhong. Palmitic acid-capped MIL-101-Al as a nano-adjuvant to amplify immune responses against Pseudomonas aeruginosa. Nanoscale. 2024 May; 16(21):10306-10317. doi: 10.1039/d4nr01180e. [PMID: 38727538]
  • Swaraj Kumar Babu, Dibya Ranjan Sahoo, Prajna Parimita Mohanta, Pradeep Kumar Naik. Exploring the antifilarial potential of an important medicinal plant Typhonium trilobatum (L. Schoot): Isolation, characterization, and structural elucidation of bioactive compounds against Brugia malayi. Journal of ethnopharmacology. 2024 May; 326(?):117858. doi: 10.1016/j.jep.2024.117858. [PMID: 38346526]
  • Ziyi Zhao, Jiandong Wang, Weimin Kong, Meredith A Newton, Wesley C Burkett, Wenchuan Sun, Lindsey Buckingham, Jillian O'Donnell, Hongyan Suo, Boer Deng, Xiaochang Shen, Xin Zhang, Tianran Hao, Chunxiao Zhou, Victoria L Bae-Jump. Palmitic Acid Exerts Anti-Tumorigenic Activities by Modulating Cellular Stress and Lipid Droplet Formation in Endometrial Cancer. Biomolecules. 2024 May; 14(5):. doi: 10.3390/biom14050601. [PMID: 38786008]
  • Chenyang Jin, Shuangjie Wang, Xiangyu Sui, Qingyang Meng, Guohao Wu. Low expression of ELOVL6 may be involved in fat loss in white adipose tissue of cancer-associated cachexia. Lipids in health and disease. 2024 May; 23(1):144. doi: 10.1186/s12944-024-02126-9. [PMID: 38760797]
  • Yoshihiro Shidoji. Induction of Hepatoma Cell Pyroptosis by Endogenous Lipid Geranylgeranoic Acid-A Comparison with Palmitic Acid and Retinoic Acid. Cells. 2024 May; 13(10):. doi: 10.3390/cells13100809. [PMID: 38786033]
  • Xi Chen, Kun Chen, Jun Hu, Yijun Dong, Menglong Zheng, Jiang Jiang, Qingsong Hu, Wenzhi Zhang. Palmitic acid induces lipid droplet accumulation and senescence in nucleus pulposus cells via ER-stress pathway. Communications biology. 2024 May; 7(1):539. doi: 10.1038/s42003-024-06248-9. [PMID: 38714886]
  • Sajad Malik, Shrirang Inamdar, Jhankar Acharya, Pranay Goel, Saroj Ghaskadbi. Characterization of palmitic acid toxicity induced insulin resistance in HepG2 cells. Toxicology in vitro : an international journal published in association with BIBRA. 2024 May; 97(?):105802. doi: 10.1016/j.tiv.2024.105802. [PMID: 38431059]
  • Huiquan Zhu, Pu Zhao, Xiaodan Wang, Yunna Wang, Shuwen Zhang, Xiaoyang Pang, Jiaping Lv. Fabrication of Human Milk Fat Substitute: Based on the Similarity Evaluation Model and Computer Software. Molecules (Basel, Switzerland). 2024 May; 29(9):. doi: 10.3390/molecules29092096. [PMID: 38731587]
  • Man-Ru Zhang, Bang-Yun Zuo, Yu-Chen Song, Dan-Dan Guo, Qing-Liu Li, Jin-Xiu Lyu, Hua Zhu, Jing Zhao, Peng-Zhou Hang. BDNF mimetics recover palmitic acid-induced injury in cardiomyocytes by ameliorating Akt-dependent mitochondrial impairments. Toxicology and applied pharmacology. 2024 May; 486(?):116951. doi: 10.1016/j.taap.2024.116951. [PMID: 38705401]
  • Dongxiao Liu, Ruth Cruz-Cosme, Yong Wu, Julian Leibowitz, Qiyi Tang. 2-Bromopalmitate depletes lipid droplets to inhibit viral replication. Journal of virology. 2024 Apr; 98(4):e0017124. doi: 10.1128/jvi.00171-24. [PMID: 38488361]
  • Ruimin Tian, Xianfeng Liu, Yang Xiao, Lijia Jing, Honglin Tao, Lu Yang, Xianli Meng. Huang-Lian-Jie-Du decoction drug-containing serum inhibits IL-1β secretion from D-glucose and PA induced BV2 cells via autophagy/NLRP3 signaling. Journal of ethnopharmacology. 2024 Apr; 323(?):117686. doi: 10.1016/j.jep.2023.117686. [PMID: 38160864]
  • Jinhui Dong, Xiaohui Tong, Jing Xu, Min Pan, Lei Wang, Fei Xu, Yajuan Wang, Li Li, Tongsheng Wang. Metformin improves obesity-related oligoasthenospermia via regulating the expression of HSL in testis in mice. European journal of pharmacology. 2024 Apr; 968(?):176388. doi: 10.1016/j.ejphar.2024.176388. [PMID: 38367685]
  • Maria Sofia Molonia, Federica Lina Salamone, Antonio Speciale, Antonella Saija, Francesco Cimino. D-Allulose Reduces Hypertrophy and Endoplasmic Reticulum Stress Induced by Palmitic Acid in Murine 3T3-L1 Adipocytes. International journal of molecular sciences. 2024 Apr; 25(7):. doi: 10.3390/ijms25074059. [PMID: 38612868]
  • Chaofeng Wu, Junjie Li, Hui Jia, Jiamin Zhao, Mengchen Qin, Hao Shi, Chang Liu, Jiajie Lin, Min Cai, Yong Gu, Bin Liu, Lei Gao. Indoleamine 2,3-dioxygenase 1-mediated iron metabolism in macrophages contributes to lipid deposition in nonalcoholic steatohepatitis. Journal of gastroenterology. 2024 04; 59(4):342-356. doi: 10.1007/s00535-024-02082-2. [PMID: 38402297]
  • Yu-Feng Song, Ling-Jiao Wang, Zhi Luo, Christer Hogstrand, Xiao-Hong Lai, Fei-Fei Zheng. Moderate replacement of fish oil with palmitic acid-stimulated mitochondrial fusion promotes β-oxidation by Mfn2 interacting with Cpt1α via its GTPase-domain. The Journal of nutritional biochemistry. 2024 Apr; 126(?):109559. doi: 10.1016/j.jnutbio.2023.109559. [PMID: 38158094]
  • Wuxian Zhong, Ai Zhao, Xuetao Wei, Shuai Mao, Pin Li, Qianqian Shen, Hong Zhang, Hua Jiang, Peiyu Wang, Yumei Zhang. The Effect of Sn-2 Palmitate on Blood Glucose, Lipids and Body Composition in Middle-Aged and Elderly Adults: A Randomized, Double-Blinded Controlled Trial. Nutrients. 2024 Mar; 16(7):. doi: 10.3390/nu16070973. [PMID: 38613008]
  • Yan Yang, Wen Qiu, Jiyuan Xiao, Jie Sun, Xuan Ren, Luxia Jiang. Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway. Journal of translational medicine. 2024 Mar; 22(1):309. doi: 10.1186/s12967-024-05060-7. [PMID: 38532480]
  • Juan Li, Zhengcai Ma, Zhipeng Yang, Maochun Yang, Changsheng Li, Mengmeng Li, Xiaoduo Li, Xiantao Chen, Hang Ma, Wanqun Chen, Xiaoli Ye, Xuegang Li. Integrating transcriptomics and network pharmacology to reveal the mechanisms of total Rhizoma Coptidis alkaloids against nonalcoholic steatohepatitis. Journal of ethnopharmacology. 2024 Mar; 322(?):117600. doi: 10.1016/j.jep.2023.117600. [PMID: 38103844]
  • Eugene Chang. Vitamin D Mitigates Hepatic Fat Accumulation and Inflammation and Increases SIRT1/AMPK Expression in AML-12 Hepatocytes. Molecules (Basel, Switzerland). 2024 Mar; 29(6):. doi: 10.3390/molecules29061401. [PMID: 38543036]
  • Ting Hu, Wen Zhang, Feifei Han, Rui Zhao, Hongchuan Liu, Zhuoling An. Machine learning reveals serum myristic acid, palmitic acid and heptanoylcarnitine as biomarkers of coronary artery disease risk in patients with type 2 diabetes mellitus. Clinica chimica acta; international journal of clinical chemistry. 2024 Mar; 556(?):117852. doi: 10.1016/j.cca.2024.117852. [PMID: 38438006]
  • Peipei Han, Chunhua Yuan, Xiaoyu Chen, Yuanqing Hu, Xiaodan Hu, Zhangtao Xu, Qi Guo. Metabolic signatures and potential biomarkers of sarcopenia in suburb-dwelling older Chinese: based on untargeted GC-MS and LC-MS. Skeletal muscle. 2024 Mar; 14(1):4. doi: 10.1186/s13395-024-00337-3. [PMID: 38454497]
  • Hang Pan, Longfeng Wei, Hao Zhao, Yang Xiao, Zhu Li, Haixia Ding. Perception of the Biocontrol Potential and Palmitic Acid Biosynthesis Pathway of Bacillus subtilis H2 through Merging Genome Mining with Chemical Analysis. Journal of agricultural and food chemistry. 2024 Mar; 72(9):4834-4848. doi: 10.1021/acs.jafc.3c06411. [PMID: 38401001]
  • Wendy L Hall, Aseel Alkoblan, Philippa S Gibson, Maria D'Annibale, Astrid Coekaerts, Mathilde Bauer, Johanna H Bruce, Beryle Lecomte, Armelle Penhoat, Fabienne Laugerette, Marie-Caroline Michalski, Louise J Salt, Peter J Wilde, Sarah E Berry. Postprandial lipid and vascular responses following consumption of a commercially-relevant interesterified palmitic acid-rich spread in comparison to functionally-equivalent non-interesterified spread and spreadable butter: a randomised controlled trial in healthy adults. Food & function. 2024 Mar; 15(5):2733-2750. doi: 10.1039/d3fo05324e. [PMID: 38380649]
  • Fan Zhang, Guangping Li, Xueyin Li, Yi Zheng, Wanting Du, Bo Zhao, Da Sun. Creation of an Atherosclerosis Model Using Palmitic Acid and Oleic Acid in the Vascular Smooth Muscle Cells of Rats. Discovery medicine. 2024 Mar; 36(182):538-545. doi: 10.24976/discov.med.202436182.50. [PMID: 38531794]
  • Qiuyan Liu, Ji Li, Yuefeng Huang, Yueping Luo, Ruijie Li, Yuanchen He, Caian He, Qiang Peng, Min Wang. Preparation of starch-palmitic acid complexes by three different starches: A comparative study using the method of heating treatment and autoclaving treatment. International journal of biological macromolecules. 2024 Mar; 262(Pt 1):130009. doi: 10.1016/j.ijbiomac.2024.130009. [PMID: 38336331]
  • Yang Yu, Jing Yang, Lixia Zheng, Han Su, Sunrun Cao, Xuehan Jiang, Xiyan Liu, Weiwei Liu, Zhuo Wang, Fang Meng, Hongde Xu, Deliang Wen, Chen Sun, Xiaoyu Song, Antonio Vidal-Puig, Liu Cao. Dysfunction of Akt/FoxO3a/Atg7 regulatory loop magnifies obesity-regulated muscular mass decline. Molecular metabolism. 2024 Mar; 81(?):101892. doi: 10.1016/j.molmet.2024.101892. [PMID: 38331318]
  • Jian Dong, Muzi Li, Runsheng Peng, Yuchuan Zhang, Zilin Qiao, Na Sun. ACACA reduces lipid accumulation through dual regulation of lipid metabolism and mitochondrial function via AMPK- PPARα- CPT1A axis. Journal of translational medicine. 2024 Feb; 22(1):196. doi: 10.1186/s12967-024-04942-0. [PMID: 38395901]
  • Meng-Yao Cai, Xu-Shun Jiang, Yun-Xin Wei, Rui-Zhi Wen, Xiao-Gang Du. Role of TFEB-autophagy lysosomal pathway in palmitic acid induced renal tubular epithelial cell injury. Biochemical and biophysical research communications. 2024 Feb; 696(?):149472. doi: 10.1016/j.bbrc.2024.149472. [PMID: 38241809]
  • Kévin Bernal, Charbel Touma, Béatrice Le-Grand, Sophie Rose, Selenay Degerli, Valentine Genêt, Dominique Lagadic-Gossmann, Xavier Coumoul, Corinne Martin-Chouly, Sophie Langouët, Etienne B Blanc. Assessment of endocrine disruptor impacts on lipid metabolism in a fatty acid-supplemented HepaRG human hepatic cell line. Chemosphere. 2024 Feb; 349(?):140883. doi: 10.1016/j.chemosphere.2023.140883. [PMID: 38092172]
  • Guanghui Deng, Junjie Li, Manping Huang, Yunjia Li, Hao Shi, Chaofeng Wu, Jiamin Zhao, Mengchen Qin, Chang Liu, Menghan Yang, Yunqing Wang, Yuxue Zhang, Yuxin Liao, Chuying Zhou, Jian Yang, Yunsheng Xu, Bin Liu, Lei Gao. Erchen decoction alleviates the progression of NAFLD by inhibiting lipid accumulation and iron overload through Caveolin-1 signaling. Journal of ethnopharmacology. 2024 Jan; 319(Pt 3):117320. doi: 10.1016/j.jep.2023.117320. [PMID: 37838297]
  • Lu Wei, Cheng Yang, Jerome Jeyakumar John Martin, Rui Li, Lixia Zhou, Shuanghong Cheng, Hongxing Cao, Xiaoyu Liu. Metabonomics and Transcriptomic Analysis of Free Fatty Acid Synthesis in Seedless and Tenera Oil Palm. International journal of molecular sciences. 2024 Jan; 25(3):. doi: 10.3390/ijms25031686. [PMID: 38338979]
  • Shishuo Sun, Heng Xu, Wanxin Zhao, Qihong Li, Yifan Yuan, Guopeng Zhang, Shuyu Li, Bixi Wang, Wei Zhang, Xiaoge Gao, Junnian Zheng, Qing Zhang. PA suppresses antitumor immunity of T cells by disturbing mitochondrial activity through Akt/mTOR-mediated Ca2+ flux. Cancer letters. 2024 01; 581(?):216511. doi: 10.1016/j.canlet.2023.216511. [PMID: 38013049]
  • Lucia Alcober-Boquet, Nico Kraus, Lisa Sophie Huber, Rajkumar Vutukuri, Dominik Christian Fuhrmann, Claudia Stross, Liliana Schaefer, Klaus Scholich, Stefan Zeuzem, Albrecht Piiper, Marcel H Schulz, Jonel Trebicka, Christoph Welsch, Cristina Ortiz. BI-3231, an enzymatic-inhibitor of HSD17B13, reduces lipotoxic effects induced by palmitic acid in murine and human hepatocytes. American journal of physiology. Cell physiology. 2024 Jan; ?(?):. doi: 10.1152/ajpcell.00413.2023. [PMID: 38223924]
  • Kang Chen, Guran Yu. Tetrahydroalstonine possesses protective potentials on palmitic acid stimulated SK-N-MC cells by suppression of Aβ1-42 and tau through regulation of PI3K/Akt signaling pathway. European journal of pharmacology. 2024 Jan; 962(?):176251. doi: 10.1016/j.ejphar.2023.176251. [PMID: 38061471]
  • Pham Thanh, Viet Ty Pham, Thi Quynh Trang Nguyen, Van Giang Tran, Ty Nguyen, Thi Quynh Nguyen. The composition of chemicals and anti-osteogenic properties in the volatile extracts from Homalomena gigantea rhizome. Pakistan journal of pharmaceutical sciences. 2024 Jan; 37(1(Special)):223-229. doi: ". [PMID: 38747273]
  • Xue Zhang, Yixue Xia, Lu Cao, Benlong Ji, Zhe Ge, Qingyun Zheng, Zhengtang Qi, Shuzhe Ding. PC 18:1/18:1 mediates the anti-inflammatory effects of exercise and remodels tumor microenvironment of hepatocellular carcinoma. Life sciences. 2024 Jan; 336(?):122335. doi: 10.1016/j.lfs.2023.122335. [PMID: 38103729]
  • Wen Liu, Min Zhu, Jingyi Liu, Shan Su, Xin Zeng, Fudong Fu, Yanrong Lu, Zhiyong Rao, Younan Chen. Comparison of the effects of monounsaturated fatty acids and polyunsaturated fatty acids on the lipotoxicity of islets. Frontiers in endocrinology. 2024; 15(?):1368853. doi: 10.3389/fendo.2024.1368853. [PMID: 38501107]
  • Qingting Yu, Yanzhuo Yang, Ting Xu, Yinsheng Cai, Zuisu Yang, Falei Yuan. Palmitoleic acid protects microglia from palmitate-induced neurotoxicity in vitro. PloS one. 2024; 19(1):e0297031. doi: 10.1371/journal.pone.0297031. [PMID: 38241239]
  • Yuqing Duan, Chen Chao, Jinglin Yu, Ye Liu, Shujun Wang. Effects of different sources of proteins on the formation of starch-lipid-protein complexes. International journal of biological macromolecules. 2023 Dec; 253(Pt 3):126853. doi: 10.1016/j.ijbiomac.2023.126853. [PMID: 37703984]
  • Ji-Sun Kim, Hyunjung Lee, Ahyoung Yoo, Hang Yeon Jeong, Chang Hwa Jung, Jiyun Ahn, Tae-Youl Ha. Gromwell (Lithospermum erythrorhizon) Attenuates High-Fat-Induced Skeletal Muscle Wasting by Increasing Protein Synthesis and Mitochondrial Biogenesis. Journal of microbiology and biotechnology. 2023 Dec; 34(3):1-10. doi: 10.4014/jmb.2311.11034. [PMID: 38247215]
  • J Lin, B Li, Q Xu, Y S Liu, Y L Kang, X Wang, Y Wang, Y Lei, Y L Bai, X M Li, J Zhou. DACH1 attenuated PA-induced renal tubular injury through TLR4/MyD88/NF-κB and TGF-β/Smad signalling pathway. Journal of endocrinological investigation. 2023 Dec; ?(?):. doi: 10.1007/s40618-023-02253-7. [PMID: 38147289]
  • Anna Migni, Francesca Mancuso, Tiziano Baroni, Gabriele Di Sante, Mario Rende, Francesco Galli, Desirée Bartolini. Melatonin as a Repairing Agent in Cadmium- and Free Fatty Acid-Induced Lipotoxicity. Biomolecules. 2023 12; 13(12):. doi: 10.3390/biom13121758. [PMID: 38136629]
  • Xiangyang Zhu, Fan Si, Rili Hao, Jingjie Zheng, Chen Zhang. Nuciferine Protects against Obesity-Induced Nephrotoxicity through Its Hypolipidemic, Anti-Inflammatory, and Antioxidant Effects. Journal of agricultural and food chemistry. 2023 Dec; 71(48):18769-18779. doi: 10.1021/acs.jafc.3c05735. [PMID: 38006352]
  • Na Li, Xuan Wu, Hailong Liu, Diandong Xie, Shuqi Hao, Zeyu Lu, Wei Quan, Jie Chen, Huaide Xu, Mei Li. Effect of edible oil type on the formation of protein-bound Nε-(carboxymethyl)lysine in roasted pork patties. Food research international (Ottawa, Ont.). 2023 Dec; 174(Pt 1):113628. doi: 10.1016/j.foodres.2023.113628. [PMID: 37986479]
  • Jiapei Lv, Wang Yanting, Shan Wei. Regulatory roles of ACSL5 in the anti-tumor function of palmitic acid (C16:0) via the ERK signaling pathway. European journal of histochemistry : EJH. 2023 Nov; 67(4):. doi: 10.4081/ejh.2023.3867. [PMID: 37946526]
  • Natasha Chattergoon, Samantha Louey, Sonnet S Jonker, Kent L Thornburg. Thyroid hormone increases fatty acid use in fetal ovine cardiac myocytes. Physiological reports. 2023 Nov; 11(22):e15865. doi: 10.14814/phy2.15865. [PMID: 38010207]
  • Shuai Xu, Lina Kong, Lin Li, Changyuan Wang, Jiangning Gu, Haifeng Luo, Qiang Meng. Farnesoid X receptor overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in nonalcoholic fatty liver disease. Biochimica et biophysica acta. Molecular basis of disease. 2023 Oct; 1870(2):166930. doi: 10.1016/j.bbadis.2023.166930. [PMID: 37918680]
  • Chenchen Liang, Siyuan Gao, Jianpeng Gao, Yanwen Xu, Qilong Li. Comparison of effects of HucMSCs, exosomes, and conditioned medium on NASH. Scientific reports. 2023 10; 13(1):18431. doi: 10.1038/s41598-023-45828-3. [PMID: 37891247]
  • Ibrahim Elsaid Elshahawy, Diaa Attia Marrez. Antagonistic activity of Trichoderma asperellum against Fusarium species, chemical profile and their efficacy for management of Fusarium-root rot disease in dry bean. Pest management science. 2023 Oct; ?(?):. doi: 10.1002/ps.7846. [PMID: 37874198]
  • Zuman Dou, Yulong Zhang, Waijiao Tang, Qiong Deng, Baishun Hu, Xianwei Chen, Hui Niu, Wenduo Wang, Zhuang Li, Hongwei Zhou, Nianyi Zeng. Ultrasonic effects on the degradation kinetics, structural characteristics and protective effects on hepatocyte lipotoxicity induced by palmitic acid of Pueraria Lobata polysaccharides. Ultrasonics sonochemistry. 2023 Oct; 101(?):106652. doi: 10.1016/j.ultsonch.2023.106652. [PMID: 37865008]
  • Xinran Gao, Huaizhi Sun, Shengwei Hao, Huimin Sun, Jinfang Ge. Melatonin protects HT-22 cells against palmitic acid-induced glucolipid metabolic dysfunction and cell injuries: Involved in the regulation of synaptic plasticity and circadian rhythms. Biochemical pharmacology. 2023 Oct; ?(?):115846. doi: 10.1016/j.bcp.2023.115846. [PMID: 37804870]
  • Xinyan Pan, Chunqiao Liu, Xing Wang, Ming Zhao, Zhimei Zhang, Xuemei Zhang, Chao Wang, Guangyao Song. Resveratrol improves palmitic acid‑induced insulin resistance via the DDIT4/mTOR pathway in C2C12 cells. Molecular medicine reports. 2023 Oct; 28(4):. doi: 10.3892/mmr.2023.13068. [PMID: 37594055]
  • Austin Sears, Fernanda Hentz, Jonas de Souza, Benjamin Wenner, Robert E Ward, Fernanda Batistel. Supply of palmitic, stearic, and oleic acid changes rumen fiber digestibility and microbial composition. Journal of dairy science. 2023 Sep; ?(?):. doi: 10.3168/jds.2023-23568. [PMID: 37776997]
  • Wenhui Zhu, Ming Chen, Yang Wang, Yao Chen, Yonggang Zhang, Yan Wang, Peng Liu, Ping Li. Regulation of renal lipid deposition in diabetic nephropathy on morroniside via inhibition of NF-KB/TNF-a/SREBP1c signaling pathway. Chemico-biological interactions. 2023 Sep; 385(?):110711. doi: 10.1016/j.cbi.2023.110711. [PMID: 37769864]
  • Lucia Longhitano, Alfio Distefano, Angela Maria Amorini, Laura Orlando, Sebastiano Giallongo, Daniele Tibullo, Giuseppe Lazzarino, Anna Nicolosi, Amer M Alanazi, Concetta Saoca, Vincenzo Macaione, M'hammed Aguennouz, Federico Salomone, Emanuela Tropea, Ignazio Alberto Barbagallo, Giovanni Li Volti, Giacomo Lazzarino. (+)-Lipoic Acid Reduces Lipotoxicity and Regulates Mitochondrial Homeostasis and Energy Balance in an In Vitro Model of Liver Steatosis. International journal of molecular sciences. 2023 Sep; 24(19):. doi: 10.3390/ijms241914491. [PMID: 37833939]
  • Eziuche Amadike Ugbogu, Happiness Okoro, Okezie Emmanuel, Ositadinma Chinyere Ugbogu, Celestine Nwabu Ekweogu, Miracle Uche, Emmanuel Dike Dike, Solomon Nnah Ijioma. Phytochemical characterization, anti-diarrhoeal, analgesic, anti-inflammatory activities and toxicity profile of Ananas comosus (L.) Merr (pineapple) leaf in albino rats. Journal of ethnopharmacology. 2023 Sep; 319(Pt 2):117224. doi: 10.1016/j.jep.2023.117224. [PMID: 37748634]
  • Miao Zhang, Xue Bai, Qian Du, Jiaojiao Xu, Danqing Wang, Lei Chen, Keting Dong, Ziyue Chen, Jianhong Yang. The Different Mechanisms of Lipid Accumulation in Hepatocytes Induced by Oleic Acid/Palmitic Acid and High-Fat Diet. Molecules (Basel, Switzerland). 2023 Sep; 28(18):. doi: 10.3390/molecules28186714. [PMID: 37764494]
  • John R Guyton, Michelle Ponder, Carol F Kirkpatrick. Advances in understanding palmitic acid metabolism and health risks. Journal of clinical lipidology. 2023 Sep; 17(5):571-572. doi: 10.1016/j.jacl.2023.09.011. [PMID: 37806801]
  • Sonia Salaria, J Lucas Boatwright, Nathan Johnson, Amod Madurapperumage, Priyanka Joshi, Pushparajah Thavarajah, George Vandemark, Dil Thavarajah. Fatty acid composition and genome-wide associations of a chickpea (Cicer arietinum L.) diversity panel for biofortification efforts. Scientific reports. 2023 Aug; 13(1):14002. doi: 10.1038/s41598-023-41274-3. [PMID: 37635199]
  • Po-Shun Hsu, Shu-Ting Liu, Yi-Lin Chiu, Chien-Sung Tsai. The Functional Role of Myogenin in Cardiomyoblast H9c2 Cells Treated with High Glucose and Palmitic Acid: Insights into No-Rejection Heart Transplantation. International journal of molecular sciences. 2023 Aug; 24(17):. doi: 10.3390/ijms241713031. [PMID: 37685838]
  • Oliver C Watkins, Reshma Appukuttan Pillai, Preben Selvam, Hannah E J Yong, Victoria K B Cracknell-Hazra, Neha Sharma, Amaury Cazenave-Gassiot, Anne K Bendt, Keith M Godfrey, Rohan M Lewis, Markus R Wenk, Shiao-Yng Chan. Myo-inositol alters the effects of glucose, leptin and insulin on placental palmitic acid and oleic acid metabolism. The Journal of physiology. 2023 Aug; ?(?):. doi: 10.1113/jp285036. [PMID: 37602663]
  • Prasanth Ravi, Subasankari Kumaresan, Jeyapragash Danaraj, Ushani Uthirakrishnan, Sureshkumar Pandian, Ramachandran Sivaramakrishnan, Sebastin Belcia Prakasam, Arivalagan Pugazhendhi. Anti-fouling potential and in-silico analysis of carotenoid and fatty acids from Rauvolfia tetraphylla L. Environmental research. 2023 08; 231(Pt 2):116158. doi: 10.1016/j.envres.2023.116158. [PMID: 37201709]
  • Jing Qi, Xueqing Yan, Lanqian Li, Kexin Qiu, Weizhi Huang, Zixiong Zhou. CXCL5 promotes lipotoxicity of hepatocytes through upregulating NLRP3/Caspase-1/IL-1β signaling in Kupffer cells and exacerbates nonalcoholic steatohepatitis in mice. International immunopharmacology. 2023 Aug; 123(?):110752. doi: 10.1016/j.intimp.2023.110752. [PMID: 37573690]
  • Lu Liu, Sen Sun, Xiaohua Li. A network pharmacology-based approach to explore the effect of dihydromyricetin on non-alcoholic fatty liver rats via regulating PPARG and CASP3. Molecular and cellular probes. 2023 Aug; ?(?):101926. doi: 10.1016/j.mcp.2023.101926. [PMID: 37567321]
  • Mateusz Chmielarz, Beata Sobieszczańska, Andrzej Teisseyre, Magdalena Wawrzyńska, Edyta Bożemska, Kamila Środa-Pomianek. Palmitic Acid Modulates Microglial Cell Response to Metabolic Endotoxemia in an In Vitro Study. Nutrients. 2023 Aug; 15(15):. doi: 10.3390/nu15153463. [PMID: 37571401]
  • Ying Zheng, Xiaoling Chen, Ting Lu, Zhiyong Lin, Chaoqi Liu, Ding Yuan, Chengfu Yuan. miR-871-5p / PGC1α regulates aging-induced lipid deposition in hepatocytes through fatty acid β-oxidation. The journals of gerontology. Series A, Biological sciences and medical sciences. 2023 Aug; ?(?):. doi: 10.1093/gerona/glad185. [PMID: 37539727]
  • Lin Zhu, Shuaizhen Fang, Wenwen Liu, Hong Zhang, Yaqiong Zhang, Zhuohong Xie, Puyu Yang, Jianchun Wan, Boyan Gao, Liangli Lucy Yu. The triacylglycerol structure and composition of a human milk fat substitute affect the absorption of fatty acids and calcium, lipid metabolism and bile acid metabolism in newly-weaned Sprague-Dawley rats. Food & function. 2023 Aug; ?(?):. doi: 10.1039/d2fo01800d. [PMID: 37526948]
  • Pengzhou Li, Song Dai, Xiang Gao, Weizheng Li. Guf1 overexpression improves pancreatic β cell functions in type 2 diabetes mellitus rats with Roux-en-Y gastric bypass (RYGB) surgery. Journal of physiology and biochemistry. 2023 Aug; 79(3):569-582. doi: 10.1007/s13105-023-00952-6. [PMID: 36905457]
  • Dóra Kovács, Emanuela Camera, Szilárd Póliska, Alessia Cavallo, Miriam Maiellaro, Katalin Dull, Florian Gruber, Christos C Zouboulis, Andrea Szegedi, Dániel Törőcsik. Linoleic Acid Induced Changes in SZ95 Sebocytes-Comparison with Palmitic Acid and Arachidonic Acid. Nutrients. 2023 Jul; 15(15):. doi: 10.3390/nu15153315. [PMID: 37571253]
  • Hana Nůsková, Fabiola Garcia Cortizo, Lena Sophie Schwenker, Timo Sachsenheimer, Egor Diakonov, Marcel Tiebe, Martin Schneider, Jasmin Lohbeck, Carissa Reid, Annette Kopp-Schneider, Dominic Helm, Britta Brügger, Aubry K Miller, Aurelio A Teleman. Competition for cysteine acylation by C16:0 and C18:0 derived lipids is a global phenomenon in the proteome. The Journal of biological chemistry. 2023 Jul; ?(?):105088. doi: 10.1016/j.jbc.2023.105088. [PMID: 37495107]
  • Cecilia E Villanueva, Bruno Hagenbuch. Palmitoylation of solute carriers. Biochemical pharmacology. 2023 Jul; 215(?):115695. doi: 10.1016/j.bcp.2023.115695. [PMID: 37481134]
  • Zhihao Liu, Qixiang Shang, Haimeng Li, Daozheng Fang, Zhuohuan Li, Yuqi Huang, Mimi Zhang, Kam Ming Ko, Jihang Chen. Exploring the possible mechanism(s) underlying the nephroprotective effect of Zhenwu Decoction in diabetic kidney disease: An integrated analysis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Jul; 119(?):154988. doi: 10.1016/j.phymed.2023.154988. [PMID: 37523837]
  • Yansong Li, Yuming Zhang, Qinghua Deng, Jingdong Mao, Zhenwei Jia, Mingyu Tang, Yue Zhang, Junkang Zhao, Jiaojiao Chen, Yiru Wang, Ziying Feng, Xinbo Wang, Liyin Du. Resveratrol reverses Palmitic Acid-induced cow neutrophils apoptosis through shifting glucose metabolism into lipid metabolism via Cav-1/ CPT 1-mediated FAO enhancement. The Journal of steroid biochemistry and molecular biology. 2023 Jul; 233(?):106363. doi: 10.1016/j.jsbmb.2023.106363. [PMID: 37454955]
  • Lu Jiang, Yang Liu, Yongchang Zhou, Qingyang Xu, Siyang Cheng, Junkai Yan, Yongtao Xiao, Lianshu Han, Ying Wang, Wei Cai. Targeted metabolomics unravels altered phenylalanine levels in piglets receiving total parenteral nutrition. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023 Jul; 37(7):e23014. doi: 10.1096/fj.202300261rr. [PMID: 37261736]
  • Ming-Yue Li, Li-Zhong Liu, Qihang Xin, Jiaying Zhou, Xiaoyang Zhang, Rui Zhang, Zangshu Wu, Junbo Yi, Ming Dong. Downregulation of mTORC1 and Mcl-1 by lipid-oversupply contributes to islet β-cell apoptosis and dysfunction. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2023 07; 1868(7):159332. doi: 10.1016/j.bbalip.2023.159332. [PMID: 37196823]
  • Shintaro Hamada, Yukari Mae, Tomoaki Takata, Hinako Hanada, Misaki Kubo, Sosuke Taniguchi, Takuji Iyama, Takaaki Sugihara, Hajime Isomoto. Five-Aminolevulinic Acid (5-ALA) Induces Heme Oxygenase-1 and Ameliorates Palmitic Acid-Induced Endoplasmic Reticulum Stress in Renal Tubules. International journal of molecular sciences. 2023 Jun; 24(12):. doi: 10.3390/ijms241210151. [PMID: 37373300]
  • Qiuyan Li, Xuye Jiang, Yujia Zhou, Yingying Gu, Yijie Ding, Jing Luo, Nengzhi Pang, Yan Sun, Lei Pei, Jie Pan, Mengqi Gao, Sixi Ma, Ying Xiao, De Hu, Feilong Wu, Lili Yang. Improving Mitochondrial Function in Skeletal Muscle Contributes to the Amelioration of Insulin Resistance by Nicotinamide Riboside. International journal of molecular sciences. 2023 Jun; 24(12):. doi: 10.3390/ijms241210015. [PMID: 37373163]
  • Y Zang, L H P Silva, Y C Geng, M J Lange, M A Zambom, A F Brito. Replacing ground corn with soyhulls plus palmitic acid in low metabolizable protein diets with or without rumen-protected amino acids: Effects on production and nutrient utilization in dairy cows. Journal of dairy science. 2023 Jun; 106(6):4002-4017. doi: 10.3168/jds.2022-22270. [PMID: 37105871]
  • Qingqing Du, Xiaoyun Wu, Kai Ma, Weiwei Liu, Panwen Liu, Toshihiko Hayashi, Kazunori Mizuno, Shunji Hattori, Hitomi Fujisaki, Takashi Ikejima. Silibinin alleviates ferroptosis of rat islet β cell INS-1 induced by the treatment with palmitic acid and high glucose through enhancing PINK1/parkin-mediated mitophagy. Archives of biochemistry and biophysics. 2023 May; ?(?):109644. doi: 10.1016/j.abb.2023.109644. [PMID: 37245586]
  • Alexis Felipe Rojas-Cruz, Cynthia Alexandra Martín-Jiménez, Janneth González, Yeimy González-Giraldo, Andrés Mauricio Pinzón, George E Barreto, Andrés Felipe Aristizábal-Pachón. Palmitic Acid Upregulates Type I Interferon-Mediated Antiviral Response and Cholesterol Biosynthesis in Human Astrocytes. Molecular neurobiology. 2023 May; ?(?):. doi: 10.1007/s12035-023-03366-z. [PMID: 37184765]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Maria Sofia Molonia, Antonio Speciale, Claudia Muscarà, Federica Lina Salamone, Antonella Saija, Francesco Cimino. Low concentrations of α-lipoic acid reduce palmitic acid-induced alterations in murine hypertrophic adipocytes. Natural product research. 2023 May; ?(?):1-10. doi: 10.1080/14786419.2023.2207137. [PMID: 37129014]
  • Kaile Zong, Kewei Xu, Xingjiang Zhang, Pan Wang, Zhekun Wang, Shan Yang, Huijuan Li, Hui Ke, Shengsheng He, Yunwei Hu, Yuyo Go, Xi Hui Felicia Chan, Jianxin Wu, Qing Huang. Explorating the mechanism of Huangqin Tang against skin lipid accumulation through network pharmacology and experimental validation. Journal of ethnopharmacology. 2023 May; 313(?):116581. doi: 10.1016/j.jep.2023.116581. [PMID: 37142143]
  • Hao Yu, Siru Yan, Meiyu Jin, Yunfei Wei, Lilei Zhao, Jiaqi Cheng, Lu Ding, Haihua Feng. Aescin can alleviate NAFLD through Keap1-Nrf2 by activating antioxidant and autophagy. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 May; 113(?):154746. doi: 10.1016/j.phymed.2023.154746. [PMID: 36905866]
  • Tatsuya Aoki, Jun Kinoshita, Seiichi Munesue, Toshihide Hamabe-Horiike, Takahisa Yamaguchi, Yusuke Nakamura, Koichi Okamoto, Hideki Moriyama, Keishi Nakamura, Shinichi Harada, Yasuhiko Yamamoto, Noriyuki Inaki, Sachio Fushida. Hypoxia-Induced CD36 Expression in Gastric Cancer Cells Promotes Peritoneal Metastasis via Fatty Acid Uptake. Annals of surgical oncology. 2023 May; 30(5):3125-3136. doi: 10.1245/s10434-022-12465-5. [PMID: 36042102]
  • Lijuan Lv, Xiangpei Wang, Hongmei Wu. Assessment of palmitic acid toxicity to animal hearts and other major organs based on acute toxicity, network pharmacology, and molecular docking. Computers in biology and medicine. 2023 05; 158(?):106899. doi: 10.1016/j.compbiomed.2023.106899. [PMID: 37058761]
  • Kun Zuo, Chen Fang, Yuanfeng Gao, Yuan Fu, Hongjiang Wang, Jing Li, Jiuchang Zhong, Xinchun Yang, Li Xu. Suppression of the gut microbiota-bile acid-FGF19 axis in patients with atrial fibrillation. Cell proliferation. 2023 Apr; ?(?):e13488. doi: 10.1111/cpr.13488. [PMID: 37186335]
  • Gulcin Satir, Kasim Utku Akturk, Musa Yavuz, Hayati Koknaroglu. Effects of adding rumen-protected palm oil in diet on milk fatty acid profile and lipid health indices in Kivircik ewes. Tropical animal health and production. 2023 Apr; 55(3):159. doi: 10.1007/s11250-023-03580-w. [PMID: 37058194]
  • Xiaolei Pan, Han Liang, Xinrui Zhao, Qionglin Zhang, Lei Chen, Zhuo Yue, Liwen Yin, Yongxin Jin, Fang Bai, Zhihui Cheng, Mark Bartlam, Weihui Wu. Regulatory and structural mechanisms of PvrA-mediated regulation of the PQS quorum-sensing system and PHA biosynthesis in Pseudomonas aeruginosa. Nucleic acids research. 2023 04; 51(6):2691-2708. doi: 10.1093/nar/gkad059. [PMID: 36744476]
  • Jie Wang, Feng Zhang, Weiwei Yang, Dandan Gao, Linglong Yang, Chenhua Yu, Chengshui Chen, Xiaokun Li, Jin-San Zhang. FGF1 ameliorates obesity-associated hepatic steatosis by reversing IGFBP2 hypermethylation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023 04; 37(4):e22881. doi: 10.1096/fj.202201950r. [PMID: 36934380]
  • Danqing Wang, Miao Zhang, Jiaojiao Xu, Jianhong Yang. Uncarboxylated Osteocalcin Decreases SCD1 by Activating AMPK to Alleviate Hepatocyte Lipid Accumulation. Molecules (Basel, Switzerland). 2023 Mar; 28(7):. doi: 10.3390/molecules28073121. [PMID: 37049884]
  • Cristiana Maia, Thomas Jung, Aschwin Engelen, Marília Horta Jung, Luísa Custódio. Unravelling the Lipids Content and the Fatty Acid Profiles of Eight Recently Described Halophytophthora Species and H. avicennae from the South Coast of Portugal. Marine drugs. 2023 Mar; 21(4):. doi: 10.3390/md21040227. [PMID: 37103366]
  • Saowaluk Saisomboon, Ryusho Kariya, Piyanard Boonnate, Kanlayanee Sawanyawisuth, Ubon Cha'on, Vor Luvira, Yaovalux Chamgramol, Chawalit Pairojkul, Wunchana Seubwai, Atit Silsirivanit, Sopit Wongkham, Seiji Okada, Sarawut Jitrapakdee, Kulthida Vaeteewoottacharn. Diminishing acetyl-CoA carboxylase 1 attenuates CCA migration via AMPK-NF-κB-snail axis. Biochimica et biophysica acta. Molecular basis of disease. 2023 Mar; 1869(5):166694. doi: 10.1016/j.bbadis.2023.166694. [PMID: 36972768]
  • Qin Zhou, Min Mo, Anliang Wang, Bobin Tang, Qiang He. Changes in N-nitrosamines, Residual Nitrites, Lipid Oxidation, Biogenic Amines, and Microbiota in Chinese Sausages Following Treatment with Tea Polyphenols and Their Palmitic Acid-modified Derivatives. Journal of food protection. 2023 Mar; 86(5):100072. doi: 10.1016/j.jfp.2023.100072. [PMID: 37001484]
  • Hao Kuang, Xuehua Sun, Ying Liu, Meng Tang, Yan Wei, Yingying Shi, Ruibin Li, Guohui Xiao, Jinlin Kang, Fen Wang, Jin Peng, Hui Xu, Fuxiang Zhou. Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells. The FEBS journal. 2023 Mar; ?(?):. doi: 10.1111/febs.16772. [PMID: 36906928]