Caffeic acid (BioDeep_00000000252)

 

Secondary id: BioDeep_00000027880, BioDeep_00000398020, BioDeep_00000398289, BioDeep_00000859476

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid

化学式: C9H8O4 (180.0422568)
中文名称: 3,4-二羟基肉桂酸, 咖啡酸
谱图信息: 最多检出来源 Viridiplantae(plant) 0.35%

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Caffeic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/caffeic_acid (retrieved 2024-11-22) (BioDeep RN: BioDeep_00000000252). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC(=C(C=C1C=CC(=O)O)O)O
InChI: InChI=1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2-

描述信息

Caffeic acid is a hydroxycinnamic acid that is cinnamic acid in which the phenyl ring is substituted by hydroxy groups at positions 3 and 4. It exists in cis and trans forms; the latter is the more common. It has a role as a plant metabolite, an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor, an EC 2.5.1.18 (glutathione transferase) inhibitor, an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor, an antioxidant and an EC 3.5.1.98 (histone deacetylase) inhibitor. It is a hydroxycinnamic acid and a member of catechols.
Caffeic Acid is a natural product found in Pavetta indica, Eupatorium cannabinum, and other organisms with data available.
Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities. Upon administration, caffeic acid acts as an antioxidant and prevents oxidative stress, thereby preventing DNA damage induced by free radicals. Caffeic acid targets and inhibits the histone demethylase (HDM) oncoprotein gene amplified in squamous cell carcinoma 1 (GASC1; JMJD2C; KDM4C) and inhibits cancer cell proliferation. GASC1, a member of the KDM4 subgroup of Jumonji (Jmj) domain-containing proteins, demethylates trimethylated lysine 9 and lysine 36 on histone H3 (H3K9 and H3K36), and plays a key role in tumor cell development.
Caffeic acid is a metabolite found in or produced by Saccharomyces cerevisiae.
See also: Black Cohosh (part of); Arctium lappa Root (part of); Comfrey Leaf (part of) ... View More ...
3,4-Dihydroxy-trans-cinnamate, also known as trans-Caffeate, is a polyphenol present in normal human urine positively correlated to coffee consumption and influenced by the dietary intake of diverse types of food (PMID:16870009). trans-Caffeic acid is found in many foods, some of which are flaxseed, cereal and cereal products, common grape, fruits, and common sage. It is also found in wine and coffee in free and conjugated forms.
Caffeic acid (CAS: 331-39-5) is a polyphenol present in normal human urine positively correlated to coffee consumption and influenced by the dietary intake of diverse types of food (PMID:16870009). Caffeic acid has been found to be a microbial metabolite of Escherichia (PMID: 28396925).

Caffeic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=331-39-5 (retrieved 2024-06-28) (CAS RN: 331-39-5). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).
Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).
Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).

同义名列表

85 个代谢物同义名

Caffeic acid, matrix substance for MALDI-MS, >=99.0\\% (HPLC), powder, light beige; InChI=1/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2; Caffeic acid, United States Pharmacopeia (USP) Reference Standard; trans-Caffeic acid, certified reference material, TraceCERT(R); Caffeic acid, matrix substance for MALDI-MS, >=99.0\\% (HPLC); 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, (2E)-; 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, (E)-; 2-Propenoic acid,3-(3,4-dihydroxyphenyl)-, (2E)-; CAFFEIC ACID (CONSTITUENT OF BLACK COHOSH) [DSC]; 3,4-Dihydroxycinnamic acid, predominantly trans; (2E)-3-(3,4-Dihydroxyphenyl)prop-2-enoic acid;; 2-Morpholin-4-yl-isonicotinicacidhydrochloride; (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid; (2E)-3-(3,4-Dihydroxyphenyl)-2-propenoic acid; (e)-3-(3,4-Dihydroxyphenyl)-2-propenoic acid; (E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid; (E)-3-(3,4-dihydroxyphenyl)prop-2-enoicacid; (2E)-(3,4-Dihydroxyphenyl)-2-propenoic acid; CAFFEIC ACID (CONSTITUENT OF BLACK COHOSH); 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-; 4-(2-Carboxyethenyl)-1,2-dihydroxybenzene; 3-(3,4-Dihydroxy phenyl)-2-propenoic acid; 2-Propenoic acid, 3-(3,4-dihdroxyphenyl)-; 3,4-dihydroxycinnamic acid (caffeic acid); 3-(3,4-dihydroxyphenyl)prop-2-enoic acid; (2E)-3-(3,4-dihydroxyphenyl)acrylic acid; 3-(3,4-Dihydroxyphenyl)-2-propenoic acid; 4-(2’-carboxyvinyl)-1,2-dihydroxybenzene; (E)-3-(3,4-dihydroxyphenyl)acrylic acid; 4-(2-Carboxyvinyl)-1,2-dihydroxybenzene; 4-(2Carboxyvinyl)-1,2-dihydroxybenzene; (E)-3-(3,4-dihydroxyphenyl)acrylicacid; 3-(3,4-Dihydroxyphenyl)propenoic acid; 2-Propenoic acid,4-dihydroxyphenyl)-; 8B3E4DA7-F3B0-4972-A315-2E387071737F; Caffeic acid, purum, >=95.0\\% (HPLC); 3-(3,4-dihydroxyphenyl)acrylic acid; 3,4-Dihydroxy-trans-cinnamic acid; trans-3,4-Dihydroxycinnamic Acid; 3,4-Dihydroxybenzeneacrylic acid; Trans 3,4-Dihydroxycinnamic acid; (E)-3,4-dihydroxycinnamic acid; 3,4-Dihydroxy-trans-cinnamate; Caffeic acid, >=98.0\\% (HPLC); caffeic acid, monosodium salt; Cinnamic acid, 3,4-dihydroxy-; 3,4-Dihydroxybenzeneacrylate; 3,4-Dihydroxycinnamate, XVII; 3,4-Dihydroxycinnamic acid; Cinnamic acid,4-dihydroxy-; 3,4-dihydroxycinnamic acid; caffeic acid, (E)-isomer; caffeic acid, (Z)-isomer; 3,4-dihydroxycinnamate; Caffeic acid - Natural; CAFFEIC ACID [WHO-DD]; Caffeic acid, trans-; CAFFEIC ACID natural; CAFFEIC ACID [HSDB]; CAFFEIC ACID (IARC); CAFFEIC ACID [IARC]; CAFFEIC ACID [INCI]; trans-caffeic acid; CAFFEIC ACID [DSC]; CAFFEIC ACID [MI]; Caffeic acid pure; (e)-Caffeic acid; cis-caffeic acid; Caffeic Acid,(S); Caffeic acid, 1; UNII-U2S3A33KVM; sodium caffeate; trans-Caffeate; caffeic-acid; Caffeic Acid; Tox21_500208; Tox21_200648; Caffeicacid; U2S3A33KVM; AI3-63211; Caffeate; Caffeic; DHCA; Caffeate; Caffeate



数据库引用编号

45 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2882 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Fan-Zhi Bu, Su-Su Meng, Ling-Yang Wang, Zhi-Yong Wu, Yan-Tuan Li. Bifonazole caffeate: The first molecular salt of bifonazole with enhanced biopharmaceutical property based on experiments and quantum chemistry research. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2024 Sep; 317(?):124403. doi: 10.1016/j.saa.2024.124403. [PMID: 38710138]
  • Jinyue He, Zhuoen He, Hao Wang, Chi Zhang, Tingting Pei, Shihua Yan, Yangtian Yan, Fujing Wang, Yuchi Chen, Ningning Yuan, Mingqing Wang, Wei Xiao. Caffeic acid alleviates skeletal muscle atrophy in 5/6 nephrectomy rats through the TLR4/MYD88/NF-kB pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 May; 174(?):116556. doi: 10.1016/j.biopha.2024.116556. [PMID: 38636398]
  • Wei Fang, Mingyu Jin, Wentao Qi, Chunli Kong, Ge Song, Wenting Peng, Yong Wang. Caffeic acid combined with arabinoxylan or β-glucan attenuates diet-induced obesity in mice via modulation of gut microbiota and metabolites. International journal of biological macromolecules. 2024 May; 268(Pt 2):131683. doi: 10.1016/j.ijbiomac.2024.131683. [PMID: 38649076]
  • Jiahui Yu, Jingchen Xie, Miao Sun, Suhui Xiong, Chunfang Xu, Zhimin Zhang, Minjie Li, Chun Li, Limei Lin. Plant-Derived Caffeic Acid and Its Derivatives: An Overview of Their NMR Data and Biosynthetic Pathways. Molecules (Basel, Switzerland). 2024 Apr; 29(7):. doi: 10.3390/molecules29071625. [PMID: 38611904]
  • Maciej Jakobina, Jacek Łyczko, Antoni Szumny, Renata Galek. The influence of cultivation conditions on the formation of psychoactive salvinorin A, salvinorin B, rosmarinic acid and caffeic acid in Coleus scutellarioides. Scientific reports. 2024 03; 14(1):6693. doi: 10.1038/s41598-024-57399-y. [PMID: 38509159]
  • Jiang-Yan Chen, Sheng Guo, Xiao-Xue Xu, Ya Yang, Yue Zhu, Hong-Jie Kang, Jin-Ao Duan. [Comparison of in vivo pharmacokinetics of twelve constituents in Qihe Fenqing Yin in normal rats and diabetic rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2024 Mar; 49(5):1378-1387. doi: 10.19540/j.cnki.cjcmm.20231210.201. [PMID: 38621986]
  • Yi Xiao, Cao-An Hong, Fang Liu, Dandan Shi, Xinting Zhu, Changyan Yu, Nian Jiang, Sanhua Li, Yun Liu. Caffeic acid activates mitochondrial UPR to resist pathogen infection in Caenorhabditis elegans via the transcription factor ATFS-1. Infection and immunity. 2024 Jan; ?(?):e0049423. doi: 10.1128/iai.00494-23. [PMID: 38294242]
  • Shaweta Sharma, Pawan Kumar Malhotra, Meenakshi Goyal, Vishal Sharma, Amandeep Mittal, Inderjit Singh Yadav, Gulzar Singh Sanghera, Parveen Chhuneja. Characterization of sugarcane mutants developed through gamma irradiations for their lignin content and caffeic acid-O-methyl transferase (COMT) gene mutations. International journal of radiation biology. 2024; 100(4):619-626. doi: 10.1080/09553002.2023.2295962. [PMID: 38166242]
  • Mei-Ling Chen, Hui-Yu Jiang, Jun Zeng, Ling Huang, Chuan-Zhu Lv. Caffeic acid attenuates tissue damage and inflammatory response in Klebsiella pneumonia by modulating AhR-Src-STAT3-IL-10 signaling pathway. Environmental toxicology. 2023 Dec; ?(?):. doi: 10.1002/tox.24086. [PMID: 38148636]
  • Marika Mróz, Barbara Kusznierewicz. Phytochemical screening and biological evaluation of Greek sage (Salvia fruticosa Mill.) extracts. Scientific reports. 2023 12; 13(1):22309. doi: 10.1038/s41598-023-49695-w. [PMID: 38102229]
  • Erik K R Hanko, João Correia, Caio S Souza, Alison Green, Jakub Chromy, Ruth Stoney, Cunyu Yan, Eriko Takano, Diana Lousa, Cláudio M Soares, Rainer Breitling. Microbial production of the plant flavanone hesperetin from caffeic acid. BMC research notes. 2023 Nov; 16(1):343. doi: 10.1186/s13104-023-06620-8. [PMID: 37978406]
  • Xiuli Li, Lumin Yang, Meng Hao, Tingting Song, Yufeng He, Mingchuan Yang, Jinsong Zhang. Chlorogenic acid as an indispensible partner of caffeic acid in coffee via selective regulation of prooxidative actions of caffeic acid. Food research international (Ottawa, Ont.). 2023 Nov; 173(Pt 2):113482. doi: 10.1016/j.foodres.2023.113482. [PMID: 37803805]
  • Jin-Chao Xiao, Ling Wang, Li Zhang, Ming-Yan Chi, Yong Huang, Zi-Peng Gong, Lin Zheng, Feng He. [Determination of plasma protein binding rate of Shuganning Injection using equilibrium dialysis and UPLC-MS/MS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Nov; 48(22):6183-6190. doi: 10.19540/j.cnki.cjcmm.20230618.204. [PMID: 38114225]
  • Enade P Istyastono, Nunung Yuniarti, Vivitri D Prasasty, Sudi Mungkasi, Stephanus S W Waskitha, Michael R S Yanuar, Florentinus D O Riswanto. Caffeic Acid in Spent Coffee Grounds as a Dual Inhibitor for MMP-9 and DPP-4 Enzymes. Molecules (Basel, Switzerland). 2023 Oct; 28(20):. doi: 10.3390/molecules28207182. [PMID: 37894660]
  • Xin-Nan Li, Nian-Ying Shang, Yu-Ying Kang, Ning Sheng, Jia-Qi Lan, Jing-Shu Tang, Lei Wu, Jin-Lan Zhang, Ying Peng. Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway. Acta pharmacologica Sinica. 2023 Oct; ?(?):. doi: 10.1038/s41401-023-01177-5. [PMID: 37833536]
  • Yi-Fen Chiang, I-Cheng Lin, Ko-Chieh Huang, Hsin-Yuan Chen, Mohamed Ali, Yun-Ju Huang, Shih-Min Hsia. Caffeic acid's role in mitigating polycystic ovary syndrome by countering apoptosis and ER stress triggered by oxidative stress. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Oct; 166(?):115327. doi: 10.1016/j.biopha.2023.115327. [PMID: 37619480]
  • Aytül Uzun Akgeyik, Emine Yalçın, Kültiğin Çavuşoğlu. Phytochemical fingerprint and biological activity of raw and heat-treated Ornithogalum umbellatum. Scientific reports. 2023 08; 13(1):13733. doi: 10.1038/s41598-023-41057-w. [PMID: 37612432]
  • Aleksandra Petrović, Višnja Madić, Gordana Stojanović, Ivana Zlatanović, Bojan Zlatković, Perica Vasiljević, Ljubiša Đorđević. Antidiabetic effects of polyherbal mixture made of Centaurium erythraea, Cichorium intybus and Potentilla erecta. Journal of ethnopharmacology. 2023 Aug; ?(?):117032. doi: 10.1016/j.jep.2023.117032. [PMID: 37582477]
  • Phuong Hong Le, Linh Thuy Thi Ho, Dao Hong Thi Le, Viet Nguyen. Purification of Coffee Polyphenols Extracted from Coffee Pulps (Coffee arabica L.) Using Aqueous Two-Phase System. Molecules (Basel, Switzerland). 2023 Aug; 28(15):. doi: 10.3390/molecules28155922. [PMID: 37570892]
  • Farkhondeh Safari, Hamid Hassanpour, Ahmad Alijanpour. Evaluation of hackberry (Celtis australis L.) fruits as sources of bioactive compounds. Scientific reports. 2023 07; 13(1):12233. doi: 10.1038/s41598-023-39421-x. [PMID: 37507445]
  • Xiao-Jing Lin, Zheng-Shi-Yu Lai, Qun Luo, Mei Kong, Min-Jian Liang, Hong Wu, Mei Bai. Correlation between Polyphenol Contents and Antioxidant Activities in Different Echinacea Purpurea Varieties. Current medical science. 2023 Jul; ?(?):. doi: 10.1007/s11596-022-2647-8. [PMID: 37480412]
  • Yueting Yu, Jia Wang, Qingze Liu, Fangyong Wei, Xuejun Xie, Mei Zhang. Integrated serum pharmacochemistry and serum pharmacology to investigate the active components and mechanism of Bushen Huoxue Prescription in the treatment of diabetic retinopathy. Journal of pharmaceutical and biomedical analysis. 2023 Jul; 235(?):115586. doi: 10.1016/j.jpba.2023.115586. [PMID: 37494766]
  • Chunliu Wang, Jie Zhou, Shixiang Wang, Yang Liu, Kaihua Long, Tingting Sun, Wenbing Zhi, Yang Yang, Hong Zhang, Ye Zhao, Xiaopu Zheng, Xiaohui Zheng, Ye Li, Pu Jia. Guanxining injection alleviates fibrosis in heart failure mice and regulates SLC7A11/GPX4 axis. Journal of ethnopharmacology. 2023 Jun; 310(?):116367. doi: 10.1016/j.jep.2023.116367. [PMID: 36914037]
  • Flávia Almeida Santos, Ana Flávia Seraine Custódio Viana, Paulo Iury Gomes Nunes, Benedito Yago Machado Portela, Ana Paula Negreiros Nunes Alves, Daniel de Araújo Viana, Kaline Rodrigues Carvalho, Rita de Cássia Alves Pereira, Paulo Riceli Vasconcelos Ribeiro, Elenilson Godoy Alves-Filho, Edy Sousa de Brito, Edilberto Rocha Silveira, Kirley Marques Canuto. UPLC-QTOF-MS/MS-based metabolomic approach and gastroprotective effect of two chemotypes of Egletes viscosa (L.) less. against ethanol-induced gastric ulcer in mice. Journal of ethnopharmacology. 2023 Jun; 309(?):116348. doi: 10.1016/j.jep.2023.116348. [PMID: 36894109]
  • Rupesh Banerjee, Barun Das Gupta, Amit Kar, Pardeep Kumar Bhardwaj, Nanaocha Sharma, Pallab Kanti Haldar, Rajib Bandyopadhyay, Pulok Kumar Mukherjee. Quality evaluation of different black rice varieties of northeastern region of India. Phytochemical analysis : PCA. 2023 May; ?(?):. doi: 10.1002/pca.3230. [PMID: 37192739]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Peng Zheng, Jieyu Ge, Jiayi Ji, Jingling Zhong, Hongyu Chen, Daren Luo, Wei Li, Bo Bi, Yongjun Ma, Wanghui Tong, Leiqin Han, Siqi Ma, Yuqi Zhang, Jianping Wu, Yanqiu Zhao, Ronghui Pan, Pengxiang Fan, Mengzhu Lu, Hao Du. Metabolic engineering and mechanical investigation of enhanced plant autoluminescence. Plant biotechnology journal. 2023 May; ?(?):. doi: 10.1111/pbi.14068. [PMID: 37155328]
  • Godfrey R Matowane, Samson S Mashele, Tshepiso J Makhafola, Chika I Chukwuma. The ameliorative effect of zinc acetate with caffeic acid in the animal model of type 2 diabetes. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Apr; 163(?):114779. doi: 10.1016/j.biopha.2023.114779. [PMID: 37119739]
  • Lin Lin, Shuangxi Peng, Xiaochen Chen, Changzhu Li, Haiying Cui. Silica nanoparticles loaded with caffeic acid to optimize the performance of cassava starch/sodium carboxymethyl cellulose film for meat packaging. International journal of biological macromolecules. 2023 Apr; 241(?):124591. doi: 10.1016/j.ijbiomac.2023.124591. [PMID: 37116847]
  • Aline Yammine, Lizette Auezova, Gérard Lizard, Hélène Greige-Gerges. Activity of Na+/K+- and Ca2+-ATPases in human erythrocyte membranes: Protocol improvement, relation to cholesterol content, and effects of polyphenols. Biochimie. 2023 Apr; 212(?):95-105. doi: 10.1016/j.biochi.2023.04.010. [PMID: 37098369]
  • Joo Young Kim, Keun Ho Cho, Shea A Keene, Thomas A Colquhoun. Altered profile of floral volatiles and lignin content by down-regulation of Caffeoyl Shikimate Esterase in Petunia. BMC plant biology. 2023 Apr; 23(1):210. doi: 10.1186/s12870-023-04203-0. [PMID: 37085749]
  • Visessakseth So, Philip Poul, Sokunvary Oeung, Pich Srey, Kimchhay Mao, Huykhim Ung, Poliny Eng, Mengkhim Heim, Marnick Srun, Chantha Chheng, Sin Chea, Tarapong Srisongkram, Natthida Weerapreeyakul. Bioactive Compounds, Antioxidant Activities, and HPLC Analysis of Nine Edible Sprouts in Cambodia. Molecules (Basel, Switzerland). 2023 Mar; 28(6):. doi: 10.3390/molecules28062874. [PMID: 36985845]
  • Stéphanie Andrade, Maria C Pereira, Joana A Loureiro. Caffeic acid loaded into engineered lipid nanoparticles for Alzheimer's disease therapy. Colloids and surfaces. B, Biointerfaces. 2023 Mar; 225(?):113270. doi: 10.1016/j.colsurfb.2023.113270. [PMID: 36996633]
  • Marielena Vogel Saivish, Carolina Colombelli Pacca, Vivaldo Gomes da Costa, Gabriela de Lima Menezes, Roosevelt Alves da Silva, Liliane Nebo, Gislaine Celestino Dutra da Silva, Bruno Henrique Gonçalves de Aguiar Milhim, Igor da Silva Teixeira, Tiago Henrique, Natalia Franco Bueno Mistrão, Victor Miranda Hernandes, Nathalia Zini, Ana Carolina de Carvalho, Marina Alves Fontoura, Paula Rahal, Lívia Sacchetto, Rafael Elias Marques, Maurício Lacerda Nogueira. Caffeic Acid Has Antiviral Activity against Ilhéus Virus In Vitro. Viruses. 2023 Feb; 15(2):. doi: 10.3390/v15020494. [PMID: 36851709]
  • Rui Sun, Tao Wu, Shu Xing, Sheng Wei, John K Bielicki, Xuefang Pan, Mingyang Zhou, Jianbin Chen. Caffeic acid protects against atherosclerotic lesions and cognitive decline in ApoE-/- mice. Journal of pharmacological sciences. 2023 Feb; 151(2):110-118. doi: 10.1016/j.jphs.2022.12.006. [PMID: 36707176]
  • Alejandra Arancibia-Díaz, Carolina Astudillo-Castro, Claudia Altamirano, Carmen Soto-Maldonado, Mauricio Vergara-Castro, Andrés Córdova, María Elvira Zúñiga-Hansen. Development of solid-state fermentation process of spent coffee grounds for the differentiated obtaining of chlorogenic, quinic, and caffeic acids. Journal of the science of food and agriculture. 2023 Jan; 103(1):420-427. doi: 10.1002/jsfa.12156. [PMID: 36373791]
  • Junying Ma, Xiaoyan Li, Maolin He, Yanwen Li, Wei Lu, Mengyao Li, Bo Sun, Yangxia Zheng. A Joint Transcriptomic and Metabolomic Analysis Reveals the Regulation of Shading on Lignin Biosynthesis in Asparagus. International journal of molecular sciences. 2023 Jan; 24(2):. doi: 10.3390/ijms24021539. [PMID: 36675053]
  • Luka Šturm, Ilja Gasan Osojnik Črnivec, Iztok Prislan, Nataša Poklar Ulrih. Comparing the Effects of Encapsulated and Non-Encapsulated Propolis Extracts on Model Lipid Membranes and Lactic Bacteria, with Emphasis on the Synergistic Effects of Its Various Compounds. Molecules (Basel, Switzerland). 2023 Jan; 28(2):. doi: 10.3390/molecules28020712. [PMID: 36677770]
  • Ling-Ling Zheng, Mei-Lan Chen, Li-Ping Kang, Ying-Li Wang, Xiu-Teng Zhou. [Effect of Rhizophagus intraradices on growth of Salvia miltiorrhiza]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Jan; 48(2):349-355. doi: 10.19540/j.cnki.cjcmm.20221017.101. [PMID: 36725224]
  • Rongrong Xing, Tingyu Xue, Peng Ye, Li Yang, Runqin Wang, Xuan Chen, Shuang Hu. pH-Responsive epitope-imprinted magnetic nanoparticles for selective separation and extraction of chlorogenic acid and caffeic acid in traditional Chinese medicines. Analytical methods : advancing methods and applications. 2022 12; 14(47):4931-4937. doi: 10.1039/d2ay01667b. [PMID: 36441178]
  • Jungwon Choi, Quynh Nhu Nguyen, Ji Yun Baek, Da-Eun Cho, Ki Sung Kang, Dae-Hyun Hahm, Tae Won Jang, Jae Ho Park, Ah Young Lee, Sanghyun Lee. Beneficial role of Boehmeria nivea in health and phytochemical constituents. Journal of food biochemistry. 2022 12; 46(12):e14474. doi: 10.1111/jfbc.14474. [PMID: 36209491]
  • Hemanjali Mude, Aniket Balapure, Anindita Thakur, Ramakrishnan Ganesan, Jayati Ray Dutta. Enhanced antibacterial, antioxidant and anticancer activity of caffeic acid by simple acid-base complexation with spermine/spermidine. Natural product research. 2022 Dec; 36(24):6453-6458. doi: 10.1080/14786419.2022.2038597. [PMID: 35142575]
  • Karin Jöhrer, Mayra Galarza Pérez, Brigitte Kircher, Serhat Sezai Çiçek. Flavones, Flavonols, Lignans, and Caffeic Acid Derivatives from Dracocephalum moldavica and Their In Vitro Effects on Multiple Myeloma and Acute Myeloid Leukemia. International journal of molecular sciences. 2022 Nov; 23(22):. doi: 10.3390/ijms232214219. [PMID: 36430695]
  • Florencia Martinez, Lucia Maria Ghietto, Giuliana Lingua, M Laura Mugas, J Javier Aguilar, Pedro Gil, M Belén Pisano, Juliana Marioni, María Gabriela Paglini, Marta S Contigiani, Susana C Núñez-Montoya, Brenda S Konigheim. New insights into the antiviral activity of nordihydroguaiaretic acid: Inhibition of dengue virus serotype 1 replication. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2022 Nov; 106(?):154424. doi: 10.1016/j.phymed.2022.154424. [PMID: 36126544]
  • Ali Naseri, Abolfazl Alirezalu, Parviz Noruzi, Kazem Alirezalu. The effect of different ammonium to nitrate ratios on antioxidant activity, morpho-physiological and phytochemical traits of Moldavian balm (Dracocephalum moldavica). Scientific reports. 2022 10; 12(1):16841. doi: 10.1038/s41598-022-21338-6. [PMID: 36207586]
  • Mustafa Abdullah Yilmaz, Abdulselam Ertas, Ismail Yener, Ozge Tokul Olmez, Mehmet Firat, Hamdi Temel, Mehmet Ozturk, Ufuk Kolak. Development and Validation of a Novel LC-MS/MS Method for the Quantitation of 19 Fingerprint Phytochemicals in Salvia Species: A Chemometric Approach. Journal of chromatographic science. 2022 Oct; 60(8):770-785. doi: 10.1093/chromsci/bmab125. [PMID: 34725681]
  • Jinqian Chen, Hao Zhang, Xia Hu, Mengyuan Xu, Yanjun Su, Chunze Zhang, Yuan Yue, Xiaomin Zhang, Xinyu Wang, Wei Cui, Zhenyu Zhao, Xichuan Li. Phloretin exhibits potential food-drug interactions by inhibiting human UDP-glucuronosyltransferases in vitro. Toxicology in vitro : an international journal published in association with BIBRA. 2022 Oct; 84(?):105447. doi: 10.1016/j.tiv.2022.105447. [PMID: 35868516]
  • Laura Ravazzolo, Benedetto Ruperti, Marco Frigo, Oriana Bertaiola, Giovanna Pressi, Mario Malagoli, Silvia Quaggiotti. C3H Expression Is Crucial for Methyl Jasmonate Induction of Chicoric Acid Production by Echinacea purpurea (L.) Moench Cell Suspension Cultures. International journal of molecular sciences. 2022 Sep; 23(19):. doi: 10.3390/ijms231911179. [PMID: 36232482]
  • Sheikh I Hossain, Mathilda Seppelt, Natalie Nguyen, Chelsea Stokes, Evelyne Deplazes. The role of ion-lipid interactions and lipid packing in transient defects caused by phenolic compounds. Biophysical journal. 2022 09; 121(18):3520-3532. doi: 10.1016/j.bpj.2022.08.001. [PMID: 35932150]
  • Miao-Yi Wu, Chia-Chu Liu, Su-Chu Lee, Yueh-Hsiung Kuo, Tusty-Jiuan Hsieh. N-Octyl Caffeamide, a Caffeic Acid Amide Derivative, Prevents Progression of Diabetes and Hepatic Steatosis in High-Fat Diet Induced Obese Mice. International journal of molecular sciences. 2022 Aug; 23(16):. doi: 10.3390/ijms23168948. [PMID: 36012215]
  • Zhicheng Zhou, Ping Han, Shiqi Bai, Ning Ma, Donglu Fang, Wenjian Yang, Qiuhui Hu, Fei Pei. Caffeic acid-grafted-chitosan/polylactic acid film packaging enhances the postharvest quality of Agaricus bisporus by regulating membrane lipid metabolism. Food research international (Ottawa, Ont.). 2022 08; 158(?):111557. doi: 10.1016/j.foodres.2022.111557. [PMID: 35840249]
  • Ehsan Ahmadifar, Sedigheh Mohammadzadeh, Naser Kalhor, Farzin Salehi, Mahboubeh Eslami, Amine Zaretabar, Mohsen S Moghadam, Seyed H Hoseinifar, Hien Van Doan. Effects of caffeic acid on the growth performance, growth genes, digestive enzyme activity, and serum immune parameters of beluga (Huso huso). Journal of experimental zoology. Part A, Ecological and integrative physiology. 2022 08; 337(7):715-723. doi: 10.1002/jez.2607. [PMID: 35652427]
  • Veronica F Salau, Ochuko L Erukainure, Omamuyovwi M Ijomone, Md Shahidul Islam. Caffeic acid regulates glucose homeostasis and inhibits purinergic and cholinergic activities while abating oxidative stress and dyslipidaemia in fructose-streptozotocin-induced diabetic rats. The Journal of pharmacy and pharmacology. 2022 Jul; 74(7):973-984. doi: 10.1093/jpp/rgac021. [PMID: 35640634]
  • Jingyang Hong, Taihua Mu, Hongnan Sun, Christophe Blecker, Aurore Richel. Photoprotective effects of sweet potato leaf polyphenols and caffeic acid against UV-induced skin-damage in BALB/C nude mice. Food & function. 2022 Jul; 13(13):7075-7087. doi: 10.1039/d2fo00425a. [PMID: 35695741]
  • Yuanyu Li, Wansheng Chen, Ying Xiao. [Advances in plant caffeic acid-O-methyltransferase]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 2022 Jun; 38(6):2187-2200. doi: 10.13345/j.cjb.210818. [PMID: 35786471]
  • Godfrey R Matowane, Limpho M Ramorobi, Samson S Mashele, Susanna L Bonnet, Anwar E M Noreljaleel, Shasank S Swain, Tshepiso J Makhafola, Chika I Chukwuma. Novel Caffeic Acid - Zinc Acetate Complex: Studies on Promising Antidiabetic and Antioxidant Synergism Through Complexation. Medicinal chemistry (Shariqah (United Arab Emirates)). 2022 Jun; ?(?):. doi: 10.2174/1573406418666220620144601. [PMID: 35726433]
  • Miao Cai, Jiayu Liu, Xiaofei Song, Hang Qi, Yuanzi Li, Zhenzhou Wu, Haijin Xu, Mingqiang Qiao. De novo biosynthesis of p-coumaric acid and caffeic acid from carboxymethyl-cellulose by microbial co-culture strategy. Microbial cell factories. 2022 May; 21(1):81. doi: 10.1186/s12934-022-01805-5. [PMID: 35538542]
  • Sanja Kostić, Aleksandra Vilotić, Andrea Pirković, Dragana Dekanski, Sunčica Borozan, Mirjana Nacka-Aleksić, Svetlana Vrzić-Petronijević, Milica Jovanović Krivokuća. Caffeic acid protects human trophoblast HTR-8/SVneo cells from H2O2-induced oxidative stress and genotoxicity. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022 May; 163(?):112993. doi: 10.1016/j.fct.2022.112993. [PMID: 35398184]
  • Raghda Abdelnasser Singab, Nooran Sherif Elleboudy, Walid Faisal Elkhatib, Mahmoud Abdulmegead Yassein, Nadia Adelhaleem Hassouna. Improvement of caffeic acid biotransformation into para-hydroxybenzoic acid by Candida albicans CI-24 via gamma irradiation and model-based optimization. Biotechnology and applied biochemistry. 2022 Apr; 69(2):469-478. doi: 10.1002/bab.2124. [PMID: 33576532]
  • Jun Lu, Yan Zhang, Ying-Zhao Wang, Yuan-Yuan Li, Rui Wang, Yu-Juan Zhong, Li Chen, Meng-Wei Song, Lin Shi, Li Li, Yong-Wen Li. Caffeic acid dimethyl ether alleviates alcohol-induced hepatic steatosis via microRNA-378b-mediated CaMKK2-AMPK pathway. Bioengineered. 2022 04; 13(4):11122-11136. doi: 10.1080/21655979.2022.2060586. [PMID: 35481488]
  • Maria Kuznowicz, Tomasz Rębiś, Artur Jędrzak, Grzegorz Nowaczyk, Mirosław Szybowicz, Teofil Jesionowski. Glucose determination using amperometric non-enzymatic sensor based on electroactive poly(caffeic acid)@MWCNT decorated with CuO nanoparticles. Mikrochimica acta. 2022 03; 189(4):159. doi: 10.1007/s00604-022-05256-y. [PMID: 35348884]
  • Monika Naumowicz, Magdalena Kusaczuk, Marcin Zając, Agata Jabłońska-Trypuć, Agnieszka Mikłosz, Miroslav Gál, Mateusz Worobiczuk, Joanna Kotyńska. The influence of the pH on the incorporation of caffeic acid into biomimetic membranes and cancer cells. Scientific reports. 2022 03; 12(1):3692. doi: 10.1038/s41598-022-07700-8. [PMID: 35256690]
  • Mirko Marino, Cristian Del Bo, Massimiliano Tucci, Samuele Venturi, Giacomo Mantegazza, Valentina Taverniti, Peter Møller, Patrizia Riso, Marisa Porrini. A mix of chlorogenic and caffeic acid reduces C/EBPß and PPAR-γ1 levels and counteracts lipid accumulation in macrophages. European journal of nutrition. 2022 Mar; 61(2):1003-1014. doi: 10.1007/s00394-021-02714-w. [PMID: 34698900]
  • Sabeeha Ali, Manzar Alam, Fatima Khatoon, Urooj Fatima, Abdelbaset Mohamed Elasbali, Mohd Adnan, Asimul Islam, Md Imtaiyaz Hassan, Mejdi Snoussi, Vincenzo De Feo. Natural products can be used in therapeutic management of COVID-19: Probable mechanistic insights. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Mar; 147(?):112658. doi: 10.1016/j.biopha.2022.112658. [PMID: 35066300]
  • Liwa Wang, Wenxia Wu, Shuge Tian. Qualitative and Quantitative Analyses of Four Active Components in Different Organs of Salvia Deserta Schang by High-Performance Thin-Layer Chromatography. Journal of chromatographic science. 2022 Feb; ?(?):. doi: 10.1093/chromsci/bmac014. [PMID: 35220420]
  • Solomon E Owumi, Chioma E Irozuru, Uche O Arunsi, Adegboyega K Oyelere. Caffeic acid protects against DNA damage, oxidative and inflammatory mediated toxicities, and upregulated caspases activation in the hepatorenal system of rats treated with aflatoxin B1. Toxicon : official journal of the International Society on Toxinology. 2022 Feb; 207(?):1-12. doi: 10.1016/j.toxicon.2021.12.021. [PMID: 34995555]
  • Nadjama B do Prado, Claudia B de Abreu, Cyndi S Pinho, Manoel M de N Junior, Mariana D Silva, Magdalena Espino, Maria F Silva, Fabio de S Dias. Application of multivariate analysis to assess stress by Cd, Pb and Al in basil (Ocimum basilicum L.) using caffeic acid, rosmarinic acid, total phenolics, total flavonoids and total dry mass in response. Food chemistry. 2022 Jan; 367(?):130682. doi: 10.1016/j.foodchem.2021.130682. [PMID: 34364147]
  • Yasmin B T Fonseca, Nicole M Almeida, Jamile C Caldas, Gabriel N Morais, Isaac M J Silva, Valéria B Riatto, Walter N L Santos, Fernando L B Moutinho. Effect of the seed coating with biomass of Dunaliella salina on early plant growth and in the secondary metabolites content of Coriandrum sativum. Anais da Academia Brasileira de Ciencias. 2022; 94(4):e20201735. doi: 10.1590/0001-3765202220201735. [PMID: 35830071]
  • Tianle Xu, Hao Zhu, Run Liu, Xinyue Wu, Guangjun Chang, Yi Yang, Zhangping Yang. The protective role of caffeic acid on bovine mammary epithelial cells and the inhibition of growth and biofilm formation of Gram-negative bacteria isolated from clinical mastitis milk. Frontiers in immunology. 2022; 13(?):1005430. doi: 10.3389/fimmu.2022.1005430. [PMID: 36341408]
  • Xinmiao Wang, Weinian Liao, Jun Chen, Yiding Wu, Chaonan Liu, Shilei Chen, Yang Xu, Song Wang, Yongping Su, Changhong Du, Junping Wang. Caffeic acid attenuates irradiation-induced hematopoietic stem cell apoptosis through inhibiting mitochondrial damage. Experimental cell research. 2021 12; 409(2):112934. doi: 10.1016/j.yexcr.2021.112934. [PMID: 34801561]
  • Rafaela Lopes, Marlene Costa, Mariana Ferreira, Paula Gameiro, Sara Fernandes, Cristina Catarino, Alice Santos-Silva, Fátima Paiva-Martins. Caffeic acid phenolipids in the protection of cell membranes from oxidative injuries. Interaction with the membrane phospholipid bilayer. Biochimica et biophysica acta. Biomembranes. 2021 12; 1863(12):183727. doi: 10.1016/j.bbamem.2021.183727. [PMID: 34400139]
  • David S Goldstein, Patti Sullivan, Abraham Corrales, Risa Isonaka, Janna Gelsomino, Jamie Cherup, Genessis Castillo, Courtney Holmes. Multiple catechols in human plasma after drinking caffeinated or decaffeinated coffee. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2021 Nov; 1185(?):122988. doi: 10.1016/j.jchromb.2021.122988. [PMID: 34731744]
  • Isadora Caruso Fontana Oliveira, Edson Hideaki Yoshida, Murilo Melo Juste Dini, Ana Beatriz Olívio Paschoal, José Carlos Cogo, Maria Alice da Cruz-Höfling, Stephen Hyslop, Yoko Oshima-Franco. Evaluation of Protection by Caffeic Acid, Chlorogenic Acid, Quercetin and Tannic Acid against the In Vitro Neurotoxicity and In Vivo Lethality of Crotalus durissus terrificus (South American Rattlesnake) Venom. Toxins. 2021 11; 13(11):. doi: 10.3390/toxins13110801. [PMID: 34822584]
  • Stéphanie Andrade, Joana Angélica Loureiro, Maria Carmo Pereira. Caffeic acid for the prevention and treatment of Alzheimer's disease: The effect of lipid membranes on the inhibition of aggregation and disruption of Aβ fibrils. International journal of biological macromolecules. 2021 Nov; 190(?):853-861. doi: 10.1016/j.ijbiomac.2021.08.198. [PMID: 34480909]
  • Tahany Saad Abdelwahab, Rania Ellisy Abdelhamed, Eman Noaman Ali, Nahla Ahmed Mansour, Mohga Shafik Abdalla. Evaluation of Silver Nanoparticles Caffeic Acid Complex Compound as New Potential Therapeutic Agent against Cancer Incidence in Mice. Asian Pacific journal of cancer prevention : APJCP. 2021 Oct; 22(10):3189-3201. doi: 10.31557/apjcp.2021.22.10.3189. [PMID: 34710995]
  • Maryam Dehdashti Moghadam, Hasan Baghshani, Hamideh Ghodrati Azadi, Zahra Moosavi. Ameliorative Effects of Caffeic Acid Against Arsenic-Induced Testicular Injury in Mice. Biological trace element research. 2021 Oct; 199(10):3772-3780. doi: 10.1007/s12011-020-02518-9. [PMID: 33394308]
  • Cheng-Wei Huang, Shih-Yi Lee, Tzu-Tang Wei, Yueh-Hsiung Kuo, Shao-Tung Wu, Hui-Chun Ku. A novel caffeic acid derivative prevents renal remodeling after ischemia/reperfusion injury. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Oct; 142(?):112028. doi: 10.1016/j.biopha.2021.112028. [PMID: 34399201]
  • Abdulmomem Awwad, Patrick Poucheret, Yanis A Idres, Damien S T Tshibangu, Adrien Servent, Karine Ferrare, Françoise Lazennec, Luc P R Bidel, Guillaume Cazals, Didier Tousch. In Vitro Tests for a Rapid Evaluation of Antidiabetic Potential of Plant Species Containing Caffeic Acid Derivatives: A Validation by Two Well-Known Antidiabetic Plants, Ocimum gratissimum L. Leaf and Musanga cecropioides R. Br. ex Tedlie (Mu) Stem Bark. Molecules (Basel, Switzerland). 2021 Sep; 26(18):. doi: 10.3390/molecules26185566. [PMID: 34577036]
  • Małgorzata Kikowska, Barbara Thiem, Karolina Jafernik, Marta Klimek-Szczykutowicz, Elżbieta Studzińska-Sroka, Halina Ekiert, Agnieszka Szopa. Effect of Elicitation with (+)-Usnic Acid on Accumulation of Phenolic Acids and Flavonoids in Agitated Microshoots of Eryngium alpinum L. Molecules (Basel, Switzerland). 2021 Sep; 26(18):. doi: 10.3390/molecules26185532. [PMID: 34577004]
  • Nellysha Namela Muhammad Abdul Kadar, Fairus Ahmad, Seong Lin Teoh, Mohamad Fairuz Yahaya. Caffeic Acid on Metabolic Syndrome: A Review. Molecules (Basel, Switzerland). 2021 Sep; 26(18):. doi: 10.3390/molecules26185490. [PMID: 34576959]
  • Haiqiang Liu, Manman Han, Jinming Li, Liang Qin, Lulu Chen, Qichen Hao, Dongxu Jiang, Difan Chen, Yuanyuan Ji, Hang Han, Chunlin Long, Yijun Zhou, Jinchao Feng, Xiaodong Wang. A Caffeic Acid Matrix Improves In Situ Detection and Imaging of Proteins with High Molecular Weight Close to 200,000 Da in Tissues by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging. Analytical chemistry. 2021 09; 93(35):11920-11928. doi: 10.1021/acs.analchem.0c05480. [PMID: 34405989]
  • Sepideh Mirzaei, Mohammad Hossein Gholami, Amirhossein Zabolian, Hossein Saleki, Mahdi Vasheghani Farahani, Soodeh Hamzehlou, Fatemeh Bakhtiari Far, Seyed Omid Sharifzadeh, Saeed Samarghandian, Haroon Khan, Amir Reza Aref, Milad Ashrafizadeh, Ali Zarrabi, Gautam Sethi. Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer. Pharmacological research. 2021 09; 171(?):105759. doi: 10.1016/j.phrs.2021.105759. [PMID: 34245864]
  • Raquel Mur, Juan I Pardo, M Rosa Pino-Otín, José S Urieta, Ana M Mainar. Supercritical Antisolvent Fractionation of Antioxidant Compounds from Salvia officinalis. International journal of molecular sciences. 2021 Aug; 22(17):. doi: 10.3390/ijms22179351. [PMID: 34502255]
  • Rajashri R Naik, Ashok K Shakya, Ghaleb A Oriquat, Shankar Katekhaye, Anant Paradkar, Hugo Fearnley, James Fearnley. Fatty Acid Analysis, Chemical Constituents, Biological Activity and Pesticide Residues Screening in Jordanian Propolis. Molecules (Basel, Switzerland). 2021 Aug; 26(16):. doi: 10.3390/molecules26165076. [PMID: 34443664]
  • Halil Ibrahim Guler, Gizem Tatar, Oktay Yildiz, Ali Osman Belduz, Sevgi Kolayli. Investigation of potential inhibitor properties of ethanolic propolis extracts against ACE-II receptors for COVID-19 treatment by molecular docking study. Archives of microbiology. 2021 Aug; 203(6):3557-3564. doi: 10.1007/s00203-021-02351-1. [PMID: 33950349]
  • Isabel Cristina da Costa Araldi, Thiele Piber de Souza, Marina de Souza Vencato, Thainara de Andrade Fortes, Camila Benaduce Emanuelli Mello, Juliana Sorraila de Oliveira, Guilherme Lopes Dornelles, Cinthia Melazzo de Andrade, Roberto Marinho Maciel, Cristiane Cademartori Danesi, Amanda Leitão Gindri, Alencar Kolinski Machado, Liliane de Freitas Bauermann. Preclinical safety assessment of the crude extract from Sida rhombifolia L. aerial parts in experimental models of acute and repeated-dose 28 days toxicity in rats. Regulatory toxicology and pharmacology : RTP. 2021 Aug; 124(?):104974. doi: 10.1016/j.yrtph.2021.104974. [PMID: 34139276]
  • Brice Cedric K Atontsa, Gabin Thierry M Bitchagno, James D Simo Mpetga, Brice Elvis N Wamba, Paul Nayim, Roland T Tchuenguem, Blanche L Ndontsa, Romeol R Koagne, Till Opatz, Victor Kuete, Pierre Tane. Caffeate and piperidine-3-ol derivatives from the stem bark of Cassia sieberiana. Natural product research. 2021 Aug; 35(15):2507-2514. doi: 10.1080/14786419.2019.1684278. [PMID: 31674835]
  • Pingping Zhou, Chunlei Yue, Bin Shen, Yi Du, Nannan Xu, Lidan Ye. Metabolic engineering of Saccharomyces cerevisiae for enhanced production of caffeic acid. Applied microbiology and biotechnology. 2021 Aug; 105(14-15):5809-5819. doi: 10.1007/s00253-021-11445-1. [PMID: 34283270]
  • Milagros Fanny Vera Castro, Naiara Stefanello, Charles Elias Assmann, Jucimara Baldissarelli, Margarete Dulce Bagatini, Aniélen Dutra da Silva, Pauline da Costa, Loren Borba, Ivana Beatrice Mânica da Cruz, Vera Maria Morsch, Maria Rosa Chitolina Schetinger. Modulatory effects of caffeic acid on purinergic and cholinergic systems and oxi-inflammatory parameters of streptozotocin-induced diabetic rats. Life sciences. 2021 Jul; 277(?):119421. doi: 10.1016/j.lfs.2021.119421. [PMID: 33785337]
  • Caigui Xiang, Moting Liu, Qiukai Lu, Chen Fan, Huimin Lu, Chunlan Feng, Xiaoqian Yang, Heng Li, Wei Tang. Blockade of TLRs-triggered macrophage activation by caffeic acid exerted protective effects on experimental ulcerative colitis. Cellular immunology. 2021 07; 365(?):104364. doi: 10.1016/j.cellimm.2021.104364. [PMID: 33932876]
  • Jingyu Ren, Yanzhong Zhen, Jian Wang, Jie Li. Catalytic degradation of caffeic acid by DBD plasma and Mn doped cobalt oxyhydroxide catalyst. Chemosphere. 2021 Jul; 275(?):130101. doi: 10.1016/j.chemosphere.2021.130101. [PMID: 33984910]
  • Lin Sun, Ananya Srinivas, Ron C Runnebaum. Understanding the Impact of Key Wine Components on the Use of a Non-Swelling Ion-Exchange Resin for Wine Protein Fining Treatment. Molecules (Basel, Switzerland). 2021 Jun; 26(13):. doi: 10.3390/molecules26133905. [PMID: 34206735]
  • Hyeri Jeong, Young-Eun Jeon, Jin-Kyoung Yang, Jaehi Kim, Woo-Jae Chung, Yoon-Sik Lee, Dong-Sik Shin. Synthesis of Caffeoyl-Prolyl-Histidyl-Xaa Derivatives and Evaluation of Their Activities and Stability upon Long-Term Storage. International journal of molecular sciences. 2021 Jun; 22(12):. doi: 10.3390/ijms22126301. [PMID: 34208348]
  • Maizatul Hasyima Omar, Rocío González Barrio, Gema Pereira-Caro, Tahani Mazyad Almutairi, Alan Crozier. In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota. International journal of food sciences and nutrition. 2021 Jun; 72(4):511-517. doi: 10.1080/09637486.2020.1850650. [PMID: 33238790]
  • Nada Oršolić, Damir Sirovina, Dyana Odeh, Goran Gajski, Vedran Balta, Lidija Šver, Maja Jazvinšćak Jembrek. Efficacy of Caffeic Acid on Diabetes and Its Complications in the Mouse. Molecules (Basel, Switzerland). 2021 May; 26(11):. doi: 10.3390/molecules26113262. [PMID: 34071554]
  • Klaudia Masztalerz, Jacek Łyczko, Krzysztof Lech. Effect of Filtrated Osmotic Solution Based on Concentrated Chokeberry Juice and Mint Extract on the Drying Kinetics, Energy Consumption and Physicochemical Properties of Dried Apples. Molecules (Basel, Switzerland). 2021 May; 26(11):. doi: 10.3390/molecules26113274. [PMID: 34071647]
  • Ancuța Chetrariu, Adriana Dabija. Spent Grain from Malt Whisky: Assessment of the Phenolic Compounds. Molecules (Basel, Switzerland). 2021 May; 26(11):. doi: 10.3390/molecules26113236. [PMID: 34072250]
  • Caroline Sefrin Speroni, Daniela Rigo Guerra, Ana Betine Beutinger Bender, Jessica Stiebe, Cristiano Augusto Ballus, Leila Picolli da Silva, Jesús Lozano-Sánchez, Tatiana Emanuelli. Micronization increases the bioaccessibility of polyphenols from granulometrically separated olive pomace fractions. Food chemistry. 2021 May; 344(?):128689. doi: 10.1016/j.foodchem.2020.128689. [PMID: 33277120]
  • Hong-Na Mu, Qi Zhou, Rui-Yue Yang, Wei-Qing Tang, Hong-Xia Li, Si-Ming Wang, Jian Li, Wen-Xiang Chen, Jun Dong. Caffeic acid prevents non-alcoholic fatty liver disease induced by a high-fat diet through gut microbiota modulation in mice. Food research international (Ottawa, Ont.). 2021 05; 143(?):110240. doi: 10.1016/j.foodres.2021.110240. [PMID: 33992352]