NCBI Taxonomy: 20025
Acalypha (ncbi_taxid: 20025)
found 25 associated metabolites at genus taxonomy rank level.
Ancestor: Acalypheae
Child Taxonomies: Acalypha rhomboidea, Acalypha aliena, Acalypha cincta, Acalypha setosa, Acalypha deamii, Acalypha dioica, Acalypha grisea, Acalypha kerrii, Acalypha ornata, Acalypha radula, Acalypha vagans, Acalypha indica, Acalypha allenii, Acalypha caturus, Acalypha crenata, Acalypha cuneata, Acalypha echinus, Acalypha filipes, Acalypha grandis, Acalypha lagopus, Acalypha lamiana, Acalypha levinii, Acalypha lyonsii, Acalypha nyasica, Acalypha plicata, Acalypha stricta, Acalypha synoica, Acalypha wilmsii, Acalypha nemorum, Acalypha radians, Acalypha ciliata, Acalypha gaumeri, Acalypha villosa, Acalypha hispida, Acalypha aristata, Acalypha acrogyna, Acalypha arvensis, Acalypha capitata, Acalypha communis, Acalypha diminuta, Acalypha insulana, Acalypha ecklonii, Acalypha gracilis, Acalypha hypogaea, Acalypha manniana, Acalypha matsudae, Acalypha mexicana, Acalypha perrieri, Acalypha pippenii, Acalypha poiretii, Acalypha saxicola, Acalypha scandens, Acalypha glabrata, Acalypha eremorum, Acalypha bisetosa, Acalypha padifolia, Acalypha amentacea, Acalypha angustata, Acalypha bipartita, Acalypha boinensis, Acalypha burquezii, Acalypha cupricola, Acalypha decaryana, Acalypha decumbens, Acalypha gillmanii, Acalypha gummifera, Acalypha hellwigii, Acalypha leptopoda, Acalypha lycioides, Acalypha virginica, Acalypha monococca, Acalypha neptunica, Acalypha ocymoides, Acalypha papillosa, Acalypha siamensis, Acalypha pubiflora, Acalypha spachiana, Acalypha stachyura, Acalypha urophylla, Acalypha volkensii, Acalypha cuspidata, Acalypha phleoides, Acalypha gracilens, Acalypha australis, Acalypha fimbriata, Acalypha fruticosa, Acalypha acmophylla, Acalypha lanceolata, Acalypha angatensis, Acalypha chordantha, Acalypha claussenii, Acalypha tricholoba, Acalypha emirnensis, Acalypha havanensis, Acalypha longispica, Acalypha lovelandii, Acalypha paniculata, Acalypha mortoniana, Acalypha schiedeana, Acalypha polymorpha, Acalypha palauensis, Acalypha subviscida, Acalypha vulneraria, Acalypha capillipes, Acalypha chirindica, Acalypha wilkesiana, Acalypha herzogiana, Acalypha filiformis, Acalypha amblyodonta, Acalypha boliviensis, Acalypha dictyoneura, Acalypha elizabethae, Acalypha fasciculata, Acalypha gillespieae, Acalypha lancetillae, Acalypha mayottensis, Acalypha membranacea, Acalypha microphylla, Acalypha monostachya, Acalypha multicaulis, Acalypha neomexicana, Acalypha californica, Acalypha pervilleana, Acalypha rafaelensis, Acalypha villicaulis, Acalypha rhombifolia, Acalypha platyphylla, Acalypha godseffiana, Acalypha ostryifolia, Acalypha ferdinandii, Acalypha cardiophylla, Acalypha peduncularis, Acalypha psilostachya, Acalypha rubroserrata, Acalypha trilaciniata, Acalypha diversifolia, Acalypha macrostachya, unclassified Acalypha, Acalypha brachystachya, Acalypha costaricensis, Acalypha grisebachiana, Acalypha glandulifolia, Acalypha medibracteata, Acalypha alopecuroidea, Acalypha portoricensis, Acalypha salvadorensis, Acalypha welwitschiana, Acalypha glechomifolia, Acalypha novoguineensis, Acalypha chamaedrifolia, Acalypha andringitrensis, Acalypha ceraceopunctata, Acalypha grandibracteata, Acalypha schlechtendaliana, Acalypha cf. glandulosa WCM-2021
Geraniin
Geraniin is a tannin. Geraniin is a natural product found in Euphorbia makinoi, Macaranga tanarius, and other organisms with data available. Geraniin is a TNF-α releasing inhibitor with numerous activities including anticancer, anti-inflammatory, and anti-hyperglycemic activities, with an IC50 of 43 μM. Geraniin is a TNF-α releasing inhibitor with numerous activities including anticancer, anti-inflammatory, and anti-hyperglycemic activities, with an IC50 of 43 μM.
Vanillic acid
Vanillic acid is a phenolic acid found in some forms of vanilla and many other plant extracts. It is a flavouring and scent agent that produces a pleasant, creamy odour. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin (J Biotechnol 1996;50(2-3):107-13). Vanillic acid, which is a chlorogenic acid, is an oxidized form of vanillin. It is also an intermediate in the production of vanillin from ferulic acid. Vanillic acid is a metabolic byproduct of caffeic acid and is often found in the urine of humans who have consumed coffee, chocolate, tea, and vanilla-flavoured confectionary. Vanillic acid selectively and specifically inhibits 5nucleotidase activity (PMID: 16899266). Vanillic acid is a microbial metabolite found in Amycolatopsis, Delftia, and Pseudomonas (PMID: 11152072, 10543794, 11728709, 9579070). Vanillic acid is a phenolic acid found in some forms of vanilla and many other plant extracts. It is a flavoring and scent agent that produces a pleasant, creamy odor. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13). Vanillic acid, which is a chlorogenic acid, is an oxidized form of vanillin. It is also an intermediate in the production of vanillin from ferulic acid. Vanillic acid is a metabolic byproduct of caffeic acid and is often found in the urine of humans who have consumed coffee, chocolate, tea and vanilla-flavored confectionary. Vanillic acid selectively and specifically inhibits 5nucleotidase activity. (PMID: 16899266). Vanillic acid is a monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a methoxy group at position 3. It has a role as a plant metabolite. It is a monohydroxybenzoic acid and a methoxybenzoic acid. It is a conjugate acid of a vanillate. Vanillic acid is a natural product found in Ficus septica, Haplophyllum cappadocicum, and other organisms with data available. Vanillic acid is a metabolite found in or produced by Saccharomyces cerevisiae. A flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13). A monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a methoxy group at position 3. Vanillic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=121-34-6 (retrieved 2024-06-29) (CAS RN: 121-34-6). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects[1]. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects[1].
Protocatechuic acid
Protocatechuic acid, also known as protocatechuate or 3,4-dihydroxybenzoate, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives. Hydroxybenzoic acid derivatives are compounds containing a hydroxybenzoic acid (or a derivative), which is a benzene ring bearing a carboxyl and a hydroxyl groups. The enzyme protocatechuate 3,4-dioxygenase uses 3,4-dihydroxybenzoate and O2 to produce 3-carboxy-cis,cis-muconate. Protocatechuic acid is a drug. In the analogous hardening of the cockroach ootheca, the phenolic substance concerned is protocatechuic acid. Protocatechuic acid is a mild, balsamic, and phenolic tasting compound. Outside of the human body, protocatechuic acid is found, on average, in the highest concentration in a few different foods, such as garden onions, cocoa powders, and star anises and in a lower concentration in lentils, liquors, and red raspberries. Protocatechuic acid has also been detected, but not quantified in several different foods, such as cloud ear fungus, american pokeweeds, common mushrooms, fruits, and feijoa. This could make protocatechuic acid a potential biomarker for the consumption of these foods. It is also found in Allium cepa (17,540 ppm). It is a major metabolite of antioxidant polyphenols found in green tea. Similarly, PCA was reported to increase proliferation and inhibit apoptosis of neural stem cells. In vitro testing documented antioxidant and anti-inflammatory activity of PCA, while liver protection in vivo was measured by chemical markers and histological assessment. 3,4-dihydroxybenzoic acid, also known as protocatechuic acid or 4-carboxy-1,2-dihydroxybenzene, belongs to hydroxybenzoic acid derivatives class of compounds. Those are compounds containing a hydroxybenzoic acid (or a derivative), which is a benzene ring bearing a carboxyl and a hydroxyl groups. 3,4-dihydroxybenzoic acid is soluble (in water) and a weakly acidic compound (based on its pKa). 3,4-dihydroxybenzoic acid can be synthesized from benzoic acid. 3,4-dihydroxybenzoic acid is also a parent compound for other transformation products, including but not limited to, methyl 3,4-dihydroxybenzoate, ethyl 3,4-dihydroxybenzoate, and 1-(3,4-dihydroxybenzoyl)-beta-D-glucopyranose. 3,4-dihydroxybenzoic acid is a mild, balsamic, and phenolic tasting compound and can be found in a number of food items such as white mustard, grape wine, abalone, and asian pear, which makes 3,4-dihydroxybenzoic acid a potential biomarker for the consumption of these food products. 3,4-dihydroxybenzoic acid can be found primarily in blood, feces, and urine, as well as in human fibroblasts and testes tissues. 3,4-dihydroxybenzoic acid exists in all eukaryotes, ranging from yeast to humans. Protocatechuic acid (PCA) is a dihydroxybenzoic acid, a type of phenolic acid. It is a major metabolite of antioxidant polyphenols found in green tea. It has mixed effects on normal and cancer cells in in vitro and in vivo studies . 3,4-dihydroxybenzoic acid is a dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4. It has a role as a human xenobiotic metabolite, a plant metabolite, an antineoplastic agent, an EC 1.1.1.25 (shikimate dehydrogenase) inhibitor and an EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor. It is a member of catechols and a dihydroxybenzoic acid. It is functionally related to a benzoic acid. It is a conjugate acid of a 3,4-dihydroxybenzoate. 3,4-Dihydroxybenzoic acid is a natural product found in Visnea mocanera, Amomum subulatum, and other organisms with data available. Protocatechuic acid is a metabolite found in or produced by Saccharomyces cerevisiae. See also: Black Cohosh (part of); Vaccinium myrtillus Leaf (part of); Menyanthes trifoliata leaf (part of) ... View More ... A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4. Protocatechuic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=99-50-3 (retrieved 2024-06-29) (CAS RN: 99-50-3). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect. Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect.
Taraxerol
Taraxerol is a pentacyclic triterpenoid that is oleanan-3-ol lacking the methyl group at position 14, with an alpha-methyl substituent at position 13 and a double bond between positions 14 and 15. It has a role as a metabolite. It is a pentacyclic triterpenoid and a secondary alcohol. Taraxerol is a natural product found in Diospyros morrisiana, Liatris acidota, and other organisms with data available. See also: Myrica cerifera root bark (part of). Constituent of Taraxacum officinale (dandelion). Taraxerol is found in many foods, some of which are kiwi, scarlet bean, prairie turnip, and grapefruit/pummelo hybrid. Taraxerol is found in alcoholic beverages. Taraxerol is a constituent of Taraxacum officinale (dandelion)
Taraxerol
Taraxerol is a pentacyclic triterpenoid that is oleanan-3-ol lacking the methyl group at position 14, with an alpha-methyl substituent at position 13 and a double bond between positions 14 and 15. It has a role as a metabolite. It is a pentacyclic triterpenoid and a secondary alcohol. Taraxerol is a natural product found in Diospyros morrisiana, Liatris acidota, and other organisms with data available. See also: Myrica cerifera root bark (part of). A pentacyclic triterpenoid that is oleanan-3-ol lacking the methyl group at position 14, with an alpha-methyl substituent at position 13 and a double bond between positions 14 and 15.
Vanillic Acid
Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects[1]. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects[1].
Columbin
Columbin is an organic heterotricyclic compound and an organooxygen compound. (2S,4AR,6aR,7R,10R,10aS,10bS)-2-(furan-3-yl)-7-hydroxy-6a,10b-dimethyl-4a,5,6,6a,7,10,10a,10b-octahydro-1H-10,7-(epoxymethano)benzo[f]isochromene-4,12(2H)-dione is a natural product found in Vateria indica, Penianthus zenkeri, and other organisms with data available. Columbin is an orally active diterpenoid furanolactone from Calumbae radix, has anti-inflammatory and anti-trypanosomal effects. Columbin selectively inhibits COX-2 (EC50=53.1 μM) over COX-1 (EC50=327 μM)[1][2]. Columbin is an orally active diterpenoid furanolactone from Calumbae radix, has anti-inflammatory and anti-trypanosomal effects. Columbin selectively inhibits COX-2 (EC50=53.1 μM) over COX-1 (EC50=327 μM)[1][2].
Vanillate
Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects[1]. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects[1].
(7r,8s,26r,28s,29s)-1,13,14,15,18,19,20,34,35,39,39-undecahydroxy-2,5,10,23,31-pentaoxo-6,9,24,27,30,40-hexaoxaoctacyclo[34.3.1.0⁴,³⁸.0⁷,²⁶.0⁸,²⁹.0¹¹,¹⁶.0¹⁷,²².0³²,³⁷]tetraconta-3,11,13,15,17(22),18,20,32,34,36-decaen-28-yl 3,4,5-trihydroxybenzoate
(1s,2r,3s,5s,8r,11r,12s)-5-(furan-3-yl)-12-hydroxy-3-methyl-6,14-dioxatetracyclo[10.2.2.0²,¹¹.0³,⁸]hexadec-15-ene-7,13-dione
(1s,2s,8r,9s,27r,29s,30r,39r)-1,2,14,15,16,19,20,21,35,36-decahydroxy-3,6,11,24,32-pentaoxo-2-(2-oxopropyl)-7,10,25,28,31,40-hexaoxaoctacyclo[35.2.1.0⁵,³⁹.0⁸,²⁷.0⁹,³⁰.0¹²,¹⁷.0¹⁸,²³.0³³,³⁸]tetraconta-4,12,14,16,18(23),19,21,33,35,37-decaen-29-yl 3,4,5-trihydroxybenzoate
(2s,3s,4s)-6-methyl-2-(4-methylphenyl)hept-5-ene-3,4-diol
(2s,3r,4s,5r,6r)-5-hydroxy-3,4-bis(3,4,5-trihydroxybenzoyloxy)-6-[(3,4,5-trihydroxybenzoyloxy)methyl]oxan-2-yl 3,4,5-trihydroxybenzoate
(4s,5r,23s,25r,26r,36s,40r)-1,10,11,12,15,16,17,31,32-nonahydroxy-2,7,20,28,35,38-hexaoxo-3,6,21,24,27,34,37-heptaoxaoctacyclo[27.10.2.0⁴,²³.0⁵,²⁶.0⁸,¹³.0¹⁴,¹⁹.0³³,⁴¹.0³⁶,⁴⁰]hentetraconta-8(13),9,11,14,16,18,29,31,33(41)-nonaen-25-yl 3,4,5-trihydroxybenzoate
(1s,4r,6r,7r,8r,17r,18s,20r,21s)-4,6,7,12,13,21-hexahydroxy-20-(hydroxymethyl)-3,15-dioxo-2,16,19,22-tetraoxapentacyclo[15.3.1.1⁷,¹⁰.0⁴,⁸.0⁹,¹⁴]docosa-9(14),10,12-trien-18-yl 3,4,5-trihydroxybenzoate
(1s,4s,5r,23s,25r,26r,36s,40r)-1,10,11,12,15,16,17,31,32-nonahydroxy-2,7,20,28,35,38-hexaoxo-3,6,21,24,27,34,37-heptaoxaoctacyclo[27.10.2.0⁴,²³.0⁵,²⁶.0⁸,¹³.0¹⁴,¹⁹.0³³,⁴¹.0³⁶,⁴⁰]hentetraconta-8(13),9,11,14,16,18,29,31,33(41)-nonaen-25-yl 3,4,5-trihydroxybenzoate
(1s,2s,3s,6r,7s,8s,9s,10r,12s)-7-[2-(furan-3-yl)-2-oxoethyl]-1-hydroxy-2,7-dimethyl-4,11,14-trioxapentacyclo[7.3.2.1³,⁶.0²,⁸.0¹⁰,¹²]pentadecane-5,13-dione
5-hydroxy-3,4-bis(3,4,5-trihydroxybenzoyloxy)-6-[(3,4,5-trihydroxybenzoyloxy)methyl]oxan-2-yl 3,4,5-trihydroxybenzoate
(2r,3s,4r,5s,6r)-3,4,5-tris(3,4,5-trihydroxybenzoyloxy)-6-[(3,4,5-trihydroxybenzoyloxy)methyl]oxan-2-yl 2-{[(1s,7s,8r,26r,28s,29r,38r)-1,13,14,15,18,20,34,35,39,39-decahydroxy-2,5,10,23,30-pentaoxo-28-(3,4,5-trihydroxybenzoyloxy)-6,9,24,27,31,40-hexaoxaoctacyclo[34.3.1.0⁴,³⁸.0⁷,²⁶.0⁸,²⁹.0¹¹,¹⁶.0¹⁷,²².0³²,³⁷]tetraconta-3,11(16),12,14,17,19,21,32,34,36-decaen-19-yl]oxy}-3,4,5-trihydroxybenzoate
(2s,3r)-2,6-dihydroxy-4-methoxy-3-{[(2r,3r,4s,5s,6s)-3,4,5,6-tetrahydroxyoxan-2-yl]oxy}-2h-pyridine-3-carbonitrile
C12H16N2O9 (332.08557659999997)