NCBI Taxonomy: 23204
Potentilla (ncbi_taxid: 23204)
found 20 associated metabolites at genus taxonomy rank level.
Ancestor: Potentilleae incertae sedis
Child Taxonomies: Potentilla nivea, Potentilla erecta, Potentilla indica, Potentilla reptans, Potentilla gordonii, Potentilla anserina, Potentilla alba, Potentilla nana, Potentilla douglasii, Potentilla norvegica, Potentilla micrantha, Potentilla hirta, Potentilla maura, Potentilla aurea, Potentilla ovina, Potentilla rubra, Potentilla recta, Potentilla verna, Potentilla nitida, Potentilla kingii, Potentilla tollii, Potentilla lyngei, Potentilla divina, Potentilla aperta, Potentilla egedei, Potentilla argaea, Potentilla effusa, Potentilla parryi, Potentilla gelida, Potentilla algida, Potentilla incana, Potentilla deorum, Potentilla pedata, Potentilla meyeri, Potentilla patula, Potentilla supina, Potentilla saxosa, Potentilla bungei, Potentilla grisea, Potentilla glabra, Potentilla suavis, Potentilla tenuis, Potentilla elegans, Potentilla biflora, Potentilla villosa, Potentilla kurdica, Potentilla pannosa, Potentilla persica, Potentilla petraea, Potentilla radiata, Potentilla iranica, Potentilla arenosa, Potentilla webberi, Potentilla rubella, Potentilla anglica, Potentilla bruceae, Potentilla collina, Potentilla crinita, Potentilla cristae, Potentilla elatior, Potentilla frigida, Potentilla cinerea, Potentilla nivalis, Potentilla turfosa, Potentilla modesta, Potentilla calabra, Potentilla festiva, Potentilla pusilla, Potentilla rivalis, Potentilla nervosa, Potentilla simplex, Potentilla subjuga, Potentilla riparia, Potentilla umbrosa, Potentilla sericea, Potentilla virgata, Potentilla arctica, Potentilla biennis, Potentilla acaulis, Potentilla montana, Potentilla cuneata, Potentilla lignosa, Potentilla taurica, Potentilla miyabei, Potentilla dombeyi, Potentilla furcata, Potentilla jaegeri, Potentilla tweedyi, Potentilla breweri, Potentilla baileyi, Potentilla lineata, Potentilla praecox, Potentilla fragarioides, Potentilla rudolfii, Potentilla uniflora, Potentilla argentea, Potentilla clusiana, Potentilla pacifica, Potentilla purpurea, Potentilla howellii, Potentilla sterilis, Potentilla alpicola, Potentilla apennina, Potentilla crantzii, Potentilla neglecta, Potentilla jepsonii, Potentilla puberula, Potentilla pamirica, Potentilla evestita, Potentilla niponica, Potentilla humifusa, Potentilla vahliana, Potentilla velutina, Potentilla wheeleri, Potentilla discolor, Potentilla lindleyi, Potentilla squamosa, Potentilla concinna, Potentilla camillae, Potentilla gracilis, Potentilla hippiana, Potentilla delavayi, Potentilla thurberi, Potentilla conferta, Potentilla strigosa, Potentilla rimicola, Potentilla longipes, Potentilla staminea, Potentilla visianii, Potentilla andicola, Potentilla finitima, Potentilla macounii, Potentilla truncata, Potentilla wilderae, Potentilla speciosa, Potentilla valderia, Potentilla tilingii, Potentilla congesta, Potentilla sericata, Potentilla sabulosa, Potentilla nubigena, Potentilla friesenii, Potentilla potaninii, Potentilla junatovii, Potentilla laciniosa, Potentilla caucasica, Potentilla pulchella, Potentilla bolanderi, Potentilla szovitsii, Potentilla pindicola, Potentilla utahensis, Potentilla albiflora, Potentilla arizonica, Potentilla brauniana, Potentilla curviseta, Potentilla lapponica, Potentilla tergemina, Potentilla volgarica, Potentilla eriocarpa, Potentilla freyniana, Potentilla anatolica, Potentilla leuconota, Potentilla litoralis, Potentilla newberryi, Potentilla kleiniana, Potentilla hispanica, Potentilla hololeuca, Potentilla pyrenaica, Potentilla villosula, Potentilla mongolica, Potentilla tetrandra, Potentilla chinensis, Potentilla multifida, Potentilla inclinata, Potentilla asperrima, Potentilla crenulata, Potentilla granulosa, Potentilla straussii, Potentilla multiceps, Potentilla smithiana, Potentilla hispidula, Potentilla stenoloba, Potentilla sanguinea, Potentilla saxifraga, Potentilla lancinata, Potentilla shockleyi, Potentilla x habievii, Potentilla caliginosa, Potentilla campestris, Potentilla crebridens, Potentilla drummondii, Potentilla neumaniana, Potentilla gorodkovii, Potentilla hyparctica, Potentilla chrysantha, Potentilla pulvinaris, Potentilla adscharica, Potentilla parvifolia, Potentilla pedersenii, Potentilla polyphylla, Potentilla articulata, Potentilla ranunculus, Potentilla daucifolia, Potentilla marinensis, Potentilla matsumurae, Potentilla canadensis, Potentilla bimundorum, Potentilla brevifolia, Potentilla desertorum, Potentilla griffithii, Potentilla carniolica, Potentilla soongorica, Potentilla hookeriana, Potentilla intermedia, Potentilla argyroloma, Potentilla aucheriana, Potentilla cardotiana, Potentilla longifolia, Potentilla millefolia, Potentilla nevadensis, Potentilla flabellata, Potentilla plattensis, Potentilla kotschyana, Potentilla rhyolitica, Potentilla oweriniana, Potentilla stipularis, Potentilla subviscosa, Potentilla centigrana, Potentilla simulatrix, Potentilla townsendii, Potentilla ruprechtii, Potentilla versicolor, Potentilla cuneifolia, Potentilla detommasii, Potentilla hypargyrea, Potentilla kryloviana, Potentilla multisecta, Potentilla caulescens, Potentilla megalantha, Potentilla nepalensis, Potentilla caruifolia, Potentilla yokusaiana, Potentilla emarginata, Potentilla lasiodonta, Potentilla uschakovii, Potentilla argyrocoma, Potentilla hebiichigo, Potentilla stolonifera, Potentilla subvahliana, Potentilla fragiformis, Potentilla microphylla, Potentilla grandiflora, Potentilla thuringiaca, Potentilla californica, Potentilla rubricaulis, Potentilla reverchonii, Potentilla clandestina, Potentilla sikkimensis, Potentilla approximata, Potentilla hendersonii, Potentilla micropetala, Potentilla anadyrensis, Potentilla heptaphylla, Potentilla astracanica, Potentilla cappadocica, Potentilla leucophylla, Potentilla carduchorum, Potentilla morefieldii, Potentilla multicaulis, Potentilla elvendensis, Potentilla ornithopoda, Potentilla geranioides, Potentilla pulcherrima, Potentilla macrosepala, Potentilla ikonnikovii, Potentilla vulcanicola, Potentilla chamissonis, Potentilla stenophylla, Potentilla angustiloba, Potentilla cryptophila, Potentilla glaucescens, Potentilla flagellaris, Potentilla mandshurica, Potentilla limprichtii, Potentilla sanguisorba, Potentilla transcaspia, Potentilla sericoleuca, Potentilla unguiculata, Potentilla x jakovlevii, Potentilla anserinoides, Potentilla montenegrina, Potentilla anemonifolia, Potentilla glabriuscula, Potentilla anachoretica, Potentilla gageodoensis, Potentilla tucumanensis, Potentilla crassinervia, Potentilla glaucophylla, Potentilla saundersiana, Potentilla pamiroalaica, Potentilla pectinisecta, Potentilla peduncularis, Potentilla brachypetala, Potentilla diversifolia, Potentilla pensylvanica, Potentilla grammopetala, Potentilla johanniniana, Potentilla oblanceolata, Potentilla sischanensis, Potentilla cryptocaulis, Potentilla quinquefolia, Potentilla purpurascens, unclassified Potentilla, Potentilla khanminczunii, Potentilla tanacetifolia, Potentilla flabellifolia, Potentilla x chemalensis, [Argentina] songzhuensis, Argentina phanerophlebia, Potentilla atrosanguinea, Potentilla santolinoides, Potentilla agrimonioides, Potentilla bipinnatifida, Potentilla eversmanniana, Potentilla jenissejensis, Potentilla ranunculoides, Potentilla subgorodkovii, Potentilla lycopodioides, Potentilla cryptotaeniae, Potentilla betonicifolia, Potentilla leucopolitana, Potentilla verticillaris, Potentilla pseudosericea, Potentilla ancistrifolia, Potentilla pimpinelloides, Potentilla multifoliolata, Potentilla astragalifolia, Potentilla fedtschenkoana, Potentilla alchimilloides, Potentilla coriandrifolia, Potentilla alchemilloides, Potentilla tabernaemontani, Potentilla turczaninowiana, Potentilla aff. verna JP-2011, Potentilla argentea x Potentilla inclinata, Potentilla pusilla x Potentilla thuringiaca
Quercetin
Quercetin appears as yellow needles or yellow powder. Converts to anhydrous form at 203-207 °F. Alcoholic solutions taste very bitter. (NTP, 1992) Quercetin is a pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3-, 4-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine. It has a role as an antibacterial agent, an antioxidant, a protein kinase inhibitor, an antineoplastic agent, an EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor, a plant metabolite, a phytoestrogen, a radical scavenger, a chelator, an Aurora kinase inhibitor and a geroprotector. It is a pentahydroxyflavone and a 7-hydroxyflavonol. It is a conjugate acid of a quercetin-7-olate. Quercetin is a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin. Quercetin is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). Quercetin is a flavonoid found in many foods and herbs and is a regular component of a normal diet. Extracts of quercetin have been used to treat or prevent diverse conditions including cardiovascular disease, hypercholesterolemia, rheumatic diseases, infections and cancer but have not been shown to be effective in clinical trials for any medical condition. Quercetin as a nutritional supplement is well tolerated and has not been linked to serum enzyme elevations or to episodes of clinically apparent liver injury. Quercetin is a natural product found in Lotus ucrainicus, Visnea mocanera, and other organisms with data available. Quercetin is a polyphenolic flavonoid with potential chemopreventive activity. Quercetin, ubiquitous in plant food sources and a major bioflavonoid in the human diet, may produce antiproliferative effects resulting from the modulation of either EGFR or estrogen-receptor mediated signal transduction pathways. Although the mechanism of action of action is not fully known, the following effects have been described with this agent in vitro: decreased expression of mutant p53 protein and p21-ras oncogene, induction of cell cycle arrest at the G1 phase and inhibition of heat shock protein synthesis. This compound also demonstrates synergy and reversal of the multidrug resistance phenotype, when combined with chemotherapeutic drugs, in vitro. Quercetin also produces anti-inflammatory and anti-allergy effects mediated through the inhibition of the lipoxygenase and cyclooxygenase pathways, thereby preventing the production of pro-inflammatory mediators. Quercetin is a flavonoid widely distributed in many plants and fruits including red grapes, citrus fruit, tomato, broccoli and other leafy green vegetables, and a number of berries, including raspberries and cranberries. Quercetin itself (aglycone quercetin), as opposed to quercetin glycosides, is not a normal dietary component. Quercitin glycosides are converted to phenolic acids as they pass through the gastrointestinal tract. Quercetin has neither been confirmed scientifically as a specific therapeutic for any condition nor been approved by any regulatory agency. The U.S. Food and Drug Administration has not approved any health claims for quercetin. Nevertheless, the interest in dietary flavonoids has grown after the publication of several epidemiological studies showing an inverse correlation between dietary consumption of flavonols and flavones and reduced incidence and mortality from cardiovascular disease and cancer. In recent years, a large amount of experimental and some clinical data have accumulated regarding the effects of flavonoids on the endothelium under physiological and pathological conditions. The meta-analysis of seven prospective cohort studies concluded that the individuals in the top third of dietary flavonol intake are associated with a reduced risk of mortality from coronary heart disease as compared with those in the bottom third, after adju... Quercetin is a flavonoid widely distributed in many plants and fruits including red grapes, citrus fruit, tomato, broccoli and other leafy green vegetables, and a number of berries, including raspberries and cranberries. Quercetin itself (aglycone quercetin), as opposed to quercetin glycosides, is not a normal dietary component. Quercetin glycosides are converted to phenolic acids as they pass through the gastrointestinal tract. Quercetin has neither been confirmed scientifically as a specific therapeutic for any condition nor been approved by any regulatory agency. The U.S. Food and Drug Administration has not approved any health claims for quercetin. Nevertheless, the interest in dietary flavonoids has grown after the publication of several epidemiological studies showing an inverse correlation between dietary consumption of flavonols and flavones and reduced incidence and mortality from cardiovascular disease and cancer. In recent years, a large amount of experimental and some clinical data have accumulated regarding the effects of flavonoids on the endothelium under physiological and pathological conditions. The meta-analysis of seven prospective cohort studies concluded that the individuals in the top third of dietary flavonol intake are associated with a reduced risk of mortality from coronary heart disease as compared with those in the bottom third, after adjustment for known risk factors and other dietary components. A limited number of intervention studies with flavonoids and flavonoid containing foods and extracts has been performed in several pathological conditions (PMID:17015250). Quercetin is isolated from many plants, especially fruits, such as Helichrysum, Euphorbia and Karwinskia spp. Present in the Solanaceae, Rhamnaceae, Passifloraceae and many other families. For example detected in almost all studied Umbelliferae. Nutriceutical with antiinflammatory props. and a positive influence on the blood lipid profile. Found in a wide variety of foods especially apples, bee pollen, blackcurrants, capers, cocoa, cranberries, dock leaves, elderberries, fennel, lovage, red onions, ancho peppers, dill weed and tarragon. A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3-, 4-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine. COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D020011 - Protective Agents > D000975 - Antioxidants Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS CONFIDENCE standard compound; INTERNAL_ID 298; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4014; ORIGINAL_PRECURSOR_SCAN_NO 4012 INTERNAL_ID 298; CONFIDENCE standard compound; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4011; ORIGINAL_PRECURSOR_SCAN_NO 4010 CONFIDENCE standard compound; INTERNAL_ID 298; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4019; ORIGINAL_PRECURSOR_SCAN_NO 4018 CONFIDENCE standard compound; INTERNAL_ID 298; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4017; ORIGINAL_PRECURSOR_SCAN_NO 4016 CONFIDENCE standard compound; INTERNAL_ID 298; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4011; ORIGINAL_PRECURSOR_SCAN_NO 4010 CONFIDENCE standard compound; INTERNAL_ID 298; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4096; ORIGINAL_PRECURSOR_SCAN_NO 4094 CONFIDENCE standard compound; INTERNAL_ID 298; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4024; ORIGINAL_PRECURSOR_SCAN_NO 4023 Acquisition and generation of the data is financially supported in part by CREST/JST. [Raw Data] CB109_Quercetin_pos_30eV_CB000041.txt IPB_RECORD: 1761; CONFIDENCE confident structure [Raw Data] CB109_Quercetin_pos_10eV_CB000041.txt [Raw Data] CB109_Quercetin_pos_20eV_CB000041.txt [Raw Data] CB109_Quercetin_pos_40eV_CB000041.txt [Raw Data] CB109_Quercetin_pos_50eV_CB000041.txt IPB_RECORD: 161; CONFIDENCE confident structure [Raw Data] CB109_Quercetin_neg_40eV_000027.txt [Raw Data] CB109_Quercetin_neg_50eV_000027.txt [Raw Data] CB109_Quercetin_neg_20eV_000027.txt [Raw Data] CB109_Quercetin_neg_30eV_000027.txt [Raw Data] CB109_Quercetin_neg_10eV_000027.txt CONFIDENCE standard compound; INTERNAL_ID 124 CONFIDENCE standard compound; ML_ID 54 Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively[1]. Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively[1].
Farnesol
Farnesol is a signaling molecule that is derived from farnesyl diphosphate, an intermediate in the isoprenoid/cholesterol biosynthetic pathway. Farnesol is a 15 carbon isoprenoid alcohol is the corresponding dephosphorylated form of the isoprenoid farnesyl diphosphate. Farnesol has a potential role in controlling the degradation of 3-hydroxy-3-methylglutaryl coenzyme A (HMGCoA) reductase (EC 1.1.1.34, NADPH-hydroxymethylglutaryl-CoA reductase). The enzyme is stabilized under conditions of cellular sterol depletion (e.g. statin-treated cells) and rapidly degraded in sterol-loaded cells. In mammalian cells, this enhanced degradation is dependent on the presence of both a sterol and a non-sterol derived from the isoprenoid pathway; farnesol, the dephosphorylated form of farnesyl diphosphate, can function as the non-sterol component. Farnesol has been shown to activate the farnesoid receptor (FXR), a nuclear receptor that forms a functional heterodimer with RXR. Thus, dephosphorylation of farnesyl diphosphate, an intermediate in the cholesterol synthetic pathway, might produce an active ligand for the FXR:RXR heterodimer. The physiological ligand for FXR remains to be identified; farnesol, may simply mimic the unidentified natural ligand(s). In addition, exogenous farnesol have an effect on several other physiological processes, including inhibition of phosphatidylcholine biosynthesis, induction of apoptosis, inhibition of cell cycle progression and actin cytoskeletal disorganization. Farnesol cellular availability is an important determinant of vascular tone in animals and humans, and provides a basis for exploring farnesyl metabolism in humans with compromised vascular function as well as for using farnesyl analogues as regulators of arterial tone in vivo. A possible metabolic fate for farnesol is its conversion to farnesoic acid, and then to farnesol-derived dicarboxylic acids (FDDCAs) which would then be excreted in the urine. Farnesol can also be oxidized to a prenyl aldehyde, presumably by an alcohol dehydrogenase (ADH), and that this activity resides in the mitochondrial and peroxisomal. Liver Endoplasmic reticulum and peroxisomal fractions are able to phosphorylate farnesol to Farnesyl diphosphate in a Cytosine triphosphate dependent fashion. (PMID: 9812197, 8636420, 9083051, 9015362). Prenol is polymerized by dehydration reactions; when there are at least four isoprene units (n in the above formula is greater than or equal to four), the polymer is called a polyprenol. Polyprenols can contain up to 100 isoprene units (n=100) linked end to end with the hydroxyl group (-OH) remaining at the end. These isoprenoid alcohols are also called terpenols These isoprenoid alcohols are important in the acylation of proteins, carotenoids, and fat-soluble vitamins A, E and K. They are also building blocks for plant oils such as farnesol and geraniol. Prenol is also a building block of cholesterol (built from six isoprene units), and thus of all steroids. Prenol has sedative properities, it is probably GABA receptor allosteric modulator.When the isoprene unit attached to the alcohol is saturated, the compound is referred to as a dolichol. Dolichols are important as glycosyl carriers in the synthesis of polysaccharides.(Wikipedia). C26170 - Protective Agent > C275 - Antioxidant Component of many flower absolutes [CCD] Farnesol is a colorless liquid with a delicate floral odor. (NTP, 1992) Farnesol is a farnesane sesquiterpenoid that is dodeca-2,6,10-triene substituted by methyl groups at positions 3, 7 and 11 and a hydroxy group at position 1. It has a role as a plant metabolite, a fungal metabolite and an antimicrobial agent. It is a farnesane sesquiterpenoid, a primary alcohol and a polyprenol. trans,trans-Farnesol is a natural product found in Lonicera japonica, Psidium guajava, and other organisms with data available. (2-trans,6-trans)-Farnesol is a metabolite found in or produced by Saccharomyces cerevisiae. A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in vertebrates. It has a delicate odor and is used in perfumery. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed) Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans, and has the activity in inhibiting bacteria. Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans, and has the activity in inhibiting bacteria.
Astragalin
Kaempferol 3-O-beta-D-glucoside is a kaempferol O-glucoside in which a glucosyl residue is attached at position 3 of kaempferol via a beta-glycosidic linkage. It has a role as a trypanocidal drug and a plant metabolite. It is a kaempferol O-glucoside, a monosaccharide derivative, a trihydroxyflavone and a beta-D-glucoside. It is a conjugate acid of a kaempferol 3-O-beta-D-glucoside(1-). Astragalin is a natural product found in Xylopia aromatica, Ficus virens, and other organisms with data available. See also: Moringa oleifera leaf (has part). Astragalin is found in alcoholic beverages. Astragalin is present in red wine. It is isolated from many plant species.Astragalin is a 3-O-glucoside of kaempferol. Astragalin is a chemical compound. It can be isolated from Phytolacca americana (the American pokeweed). A kaempferol O-glucoside in which a glucosyl residue is attached at position 3 of kaempferol via a beta-glycosidic linkage. Present in red wine. Isolated from many plant subspecies Acquisition and generation of the data is financially supported in part by CREST/JST. CONFIDENCE standard compound; INTERNAL_ID 173 Astragalin (Astragaline) a flavonoid with anti-inflammatory, antioxidant, anticancer, bacteriostatic activity. Astragalin inhibits cancer cells proliferation and migration, induces apoptosis. Astragalin is orally active and provides nerve and heart protection, and resistance against and osteoporosis[1]. Astragalin (Astragaline) a flavonoid with anti-inflammatory, antioxidant, anticancer, bacteriostatic activity. Astragalin inhibits cancer cells proliferation and migration, induces apoptosis. Astragalin is orally active and provides nerve and heart protection, and resistance against and osteoporosis[1].
Stirrup
C26170 - Protective Agent > C275 - Antioxidant Acquisition and generation of the data is financially supported in part by CREST/JST. Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans, and has the activity in inhibiting bacteria. Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans, and has the activity in inhibiting bacteria. Nerolidol is a natural membrane-active sesquiterpene, with antitumor, antibacterial, antifungal and antiparasitic activity[1]. Nerolidol is a natural membrane-active sesquiterpene, with antitumor, antibacterial, antifungal and antiparasitic activity[1]. trans-Nerolidol is a sesquiterpene alcohol. It can be isolated from f aerial parts of Warionia saharae ex Benth. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (HY-15142A) against intestinal cancer cells in vitro. trans-Nerolidol also has anti-fungal activity[1][2]. trans-Nerolidol is a sesquiterpene alcohol. It can be isolated from f aerial parts of Warionia saharae ex Benth. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (HY-15142A) against intestinal cancer cells in vitro. trans-Nerolidol also has anti-fungal activity[1][2].
Astragalin
Astragalin (Astragaline) a flavonoid with anti-inflammatory, antioxidant, anticancer, bacteriostatic activity. Astragalin inhibits cancer cells proliferation and migration, induces apoptosis. Astragalin is orally active and provides nerve and heart protection, and resistance against and osteoporosis[1]. Astragalin (Astragaline) a flavonoid with anti-inflammatory, antioxidant, anticancer, bacteriostatic activity. Astragalin inhibits cancer cells proliferation and migration, induces apoptosis. Astragalin is orally active and provides nerve and heart protection, and resistance against and osteoporosis[1].
Quercetin
Annotation level-1 COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials relative retention time with respect to 9-anthracene Carboxylic Acid is 0.898 D020011 - Protective Agents > D000975 - Antioxidants Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS relative retention time with respect to 9-anthracene Carboxylic Acid is 0.902 Acquisition and generation of the data is financially supported by the Max-Planck-Society IPB_RECORD: 1981; CONFIDENCE confident structure IPB_RECORD: 3301; CONFIDENCE confident structure IPB_RECORD: 3283; CONFIDENCE confident structure Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively[1]. Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively[1].
Farnesol
A farnesane sesquiterpenoid that is dodeca-2,6,10-triene substituted by methyl groups at positions 3, 7 and 11 and a hydroxy group at position 1. Farnesol is a colorless liquid with a delicate floral odor. (NTP, 1992) Farnesol is a farnesane sesquiterpenoid that is dodeca-2,6,10-triene substituted by methyl groups at positions 3, 7 and 11 and a hydroxy group at position 1. It has a role as a plant metabolite, a fungal metabolite and an antimicrobial agent. It is a farnesane sesquiterpenoid, a primary alcohol and a polyprenol. trans,trans-Farnesol is a natural product found in Lonicera japonica, Psidium guajava, and other organisms with data available. (2-trans,6-trans)-Farnesol is a metabolite found in or produced by Saccharomyces cerevisiae. A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in vertebrates. It has a delicate odor and is used in perfumery. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed) The (2-trans,6-trans)-stereoisomer of farnesol. C26170 - Protective Agent > C275 - Antioxidant Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans, and has the activity in inhibiting bacteria. Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans, and has the activity in inhibiting bacteria.
Quertin
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D020011 - Protective Agents > D000975 - Antioxidants Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively[1]. Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively[1].