Campesterol (BioDeep_00000000527)

 

Secondary id: BioDeep_00000017530, BioDeep_00000173721, BioDeep_00000398246, BioDeep_00000618916, BioDeep_00000860621, BioDeep_00001893179

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite natural product


代谢物信息卡片


(1S,2R,5S,10S,11S,14R,15R)-14-[(2R,5R)-5,6-dimethylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol

化学式: C28H48O (400.3705)
中文名称: 菜油甾醇
谱图信息: 最多检出来源 Homo sapiens(blood) 25.61%

Reviewed

Last reviewed on 2024-07-01.

Cite this Page

Campesterol. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/campesterol (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000000527). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1[C@@H](CC2=CC[C@@H]3[C@@H]([C@]2(C1)C)CC[C@]1([C@H]3CC[C@@H]1[C@@H](CC[C@H](C(C)C)C)C)C)O
InChI: InChI=1S/C28H48O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h9,18-20,22-26,29H,7-8,10-17H2,1-6H3/t19-,20+,22-,23-,24+,25-,26-,27-,28+/m0/s1

描述信息

Campesterol is a phytosterol, meaning it is a steroid derived from plants. As a food additive, phytosterols have cholesterol-lowering properties (reducing cholesterol absorption in intestines), and may act in cancer prevention. Phytosterols naturally occur in small amount in vegetable oils, especially soybean oil. One such phytosterol complex, isolated from vegetable oil, is cholestatin, composed of campesterol, stigmasterol, and brassicasterol, and is marketed as a dietary supplement. Sterols can reduce cholesterol in human subjects by up to 15\\\\\%. The mechanism behind phytosterols and the lowering of cholesterol occurs as follows : the incorporation of cholesterol into micelles in the gastrointestinal tract is inhibited, decreasing the overall amount of cholesterol absorbed. This may in turn help to control body total cholesterol levels, as well as modify HDL, LDL and TAG levels. Many margarines, butters, breakfast cereals and spreads are now enriched with phytosterols and marketed towards people with high cholesterol and a wish to lower it. -- Wikipedia.
Campesterol is a member of phytosterols, a 3beta-sterol, a 3beta-hydroxy-Delta(5)-steroid and a C28-steroid. It has a role as a mouse metabolite. It derives from a hydride of a campestane.
Campesterol is a natural product found in Haplophyllum bucharicum, Bugula neritina, and other organisms with data available.
Campesterol is a steroid derivative that is the simplest sterol, characterized by the hydroxyl group in position C-3 of the steroid skeleton, and saturated bonds throughout the sterol structure, with the exception of the 5-6 double bond in the B ring.

Campesterol. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=474-62-4 (retrieved 2024-07-01) (CAS RN: 474-62-4). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.
Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

同义名列表

76 个代谢物同义名

(8R,9S,10S,13R,14S,17R)-17-((2R,5R)-5,6-Dimethylheptan-2-yl)-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol; (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5,6-dimethylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; (1S,2R,5S,10S,11S,14R,15R)-14-[(2R,5R)-5,6-dimethylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol; CAMPESTEROL (CONSTITUENT OF SAW PALMETTO) [DSC]; CAMPESTEROL (CONSTITUENT OF SAW PALMETTO); CAMPESTEROL (CONSTITUENT OF PYGEUM) [DSC]; 24.alpha.-Methyl-5-cholesten-3.beta.-ol; 24 alpha-methylcholest-5-en-3 beta-ol; (24R)-24-methylcholest-5-en-3beta-ol; (24R)24-Methylcholest-5-en-3beta-ol; CAMPESTEROL (CONSTITUENT OF PYGEUM); (24R)-Methylcholest-5-en-3.beta.-ol; 24alpha-Methyl-5-cholesten-3beta-ol; Ergost-5-en-3-ol-, (24R, 3.beta.)-; .DELTA.5-24-Isoergosten-3.beta.-ol; (24R)-24-Methylcholest-5-en-3β-ol; ergost-5-en-3 beta- ol, 24 epimer; (24R)-Methylcholest-5-en-3beta-ol; campesterol, (3beta,24xi)-isomer; (24R)-Methylcholest-5-en-3β-ol; 24-Methylcholest-5-en-3beta-ol; (3.BETA.,24R)-ERGOST-5-EN-3-OL; (24R)-Methylcholest-5-en-3b-ol; Ergost-5-en-3-ol, (3beta,24R)-; delta5-24-Isoergosten-3beta-ol; (24S)-beta-Methyl cholesterol; (3-beta-24R)-Ergost-5-en-3-ol; cholest 5-en-3-ol, 24-methyl; 3 beta, 24R-ergost-5-en-3-ol; 24a-Methyl-5-cholesten-3b-ol; (3beta,24R)-ergost-5-en-3-ol; Ergost-5-en-3beta-ol, (24R)-; 24Α-methyl-5-cholesten-3β-ol; (24R)-Ergost-5-en-3-beta-ol; Ergost-5-en-3-ol, (3b,24R)-; 22,23-dihydrobrassicasterol; campesterol, (3beta)-isomer; 24.alpha.-Methylcholesterol; 24-methyl-5-Cholestene-3-ol; (24R)-Ergost-5-en-3beta-ol; 24-alpha-Methylcholesterol; (24R)-5-Ergosten-3-beta-ol; 24alpha-Methylcholesterol; (24R)-5-Ergosten-3beta-ol; (24R)ergost-5-en-3beta-ol; (3Β,24R)-ergost-5-en-3-ol; (3-beta)-Ergost-5-en-3-ol; (3b,24R)-Ergost-5-en-3-ol; 24(R)-methylcholesterol; (24R)-Ergost-5-en-3b-ol; (24R)-Ergost-5-en-3β-ol; Δ5-24-isoergosten-3β-ol; (24R)Ergost-5-en-3b-ol; (24R)-5-Ergosten-3β-ol; (24R)Ergost-5-en-3β-ol; (24R)-5-Ergosten-3b-ol; Campest-5-en-3beta-ol; Ergost-5-en-3-beta-ol; 24a-Methylcholesterol; 24Α-methylcholesterol; CAMPESTEROL [WHO-DD]; 24-methylcholesterol; Campest-5-en-3-ol; CAMPESTEROL [MI]; UNII-5L5O665639; Mieyajunsu A; Campesterin; Campasterol; Campesterol; 5L5O665639; ST 28:1;O; (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5,6-dimethylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; (24R)-5-Ergosten-3-beta-ol (24R)-5-Ergosten-3b-ol; Ergost-5-en-3-ol; Campestrol; Campesterol



数据库引用编号

30 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(4)

PlantCyc(1)

代谢反应

164 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(10)

WikiPathways(1)

Plant Reactome(5)

INOH(0)

PlantCyc(147)

COVID-19 Disease Map(0)

PathBank(1)

  • Steroid Biosynthesis: Hydrogen Ion + Lathosterol + Oxygen + ferrocytochrome b5 ⟶ 7-Dehydrocholesterol + Water + ferricytochrome b5

PharmGKB(0)

1956 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 APOB, APOE, BCL2, CASP3, PCSK9, PTGS2
Peripheral membrane protein 2 CYP1B1, PTGS2
Endosome membrane 1 APOB
Endoplasmic reticulum membrane 6 APOB, BCL2, CYP1B1, DHCR7, HMGCR, PTGS2
Nucleus 3 APOE, BCL2, CASP3
cytosol 5 APOA1, APOB, BCL2, CASP3, GPT
dendrite 1 APOE
nucleoplasm 1 CASP3
Cell membrane 5 ABCG5, ABCG8, DPP4, NPC1L1, TNF
lamellipodium 1 DPP4
Multi-pass membrane protein 5 ABCG5, ABCG8, DHCR7, HMGCR, NPC1L1
cell junction 1 DPP4
cell surface 3 DPP4, PCSK9, TNF
glutamatergic synapse 2 APOE, CASP3
Golgi apparatus 2 APOE, PCSK9
Golgi membrane 1 INS
lysosomal membrane 2 DPP4, PCSK9
neuronal cell body 4 APOB, APOE, CASP3, TNF
smooth endoplasmic reticulum 1 APOB
Lysosome 1 PCSK9
endosome 1 PCSK9
plasma membrane 9 ABCG5, ABCG8, APOA1, APOB, APOE, DPP4, NPC1L1, PCSK9, TNF
Membrane 9 ABCG5, ABCG8, APOE, BCL2, CYP1B1, DHCR7, DPP4, HMGCR, NPC1L1
apical plasma membrane 4 ABCG5, ABCG8, DPP4, NPC1L1
caveola 1 PTGS2
extracellular exosome 6 APOA1, APOB, APOE, CETP, DPP4, GPT
endoplasmic reticulum 6 APOE, BCL2, DHCR7, HMGCR, PCSK9, PTGS2
extracellular space 9 APOA1, APOB, APOE, CETP, CRP, IL6, INS, PCSK9, TNF
lysosomal lumen 1 APOB
perinuclear region of cytoplasm 1 PCSK9
intercellular canaliculus 1 DPP4
mitochondrion 2 BCL2, CYP1B1
protein-containing complex 2 BCL2, PTGS2
intracellular membrane-bounded organelle 2 APOB, CYP1B1
Microsome membrane 2 CYP1B1, PTGS2
postsynaptic density 1 CASP3
Secreted 9 APOA1, APOB, APOE, CETP, CRP, DPP4, IL6, INS, PCSK9
extracellular region 10 APOA1, APOB, APOE, CETP, CRP, DPP4, IL6, INS, PCSK9, TNF
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 2 BCL2, DPP4
mitochondrial outer membrane 1 BCL2
anchoring junction 1 DPP4
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 TNF
Endosome, multivesicular body 1 APOE
Extracellular vesicle 2 APOA1, APOE
Secreted, extracellular space, extracellular matrix 1 APOE
chylomicron 3 APOA1, APOB, APOE
high-density lipoprotein particle 3 APOA1, APOE, CETP
low-density lipoprotein particle 3 APOA1, APOB, APOE
multivesicular body 1 APOE
very-low-density lipoprotein particle 3 APOA1, APOB, APOE
cytoplasmic vesicle 1 APOA1
Early endosome 4 APOA1, APOB, APOE, PCSK9
COPII-coated ER to Golgi transport vesicle 1 PCSK9
recycling endosome 1 TNF
Single-pass type II membrane protein 2 DPP4, TNF
vesicle 1 CETP
Apical cell membrane 4 ABCG5, ABCG8, DPP4, NPC1L1
Membrane raft 2 DPP4, TNF
pore complex 1 BCL2
focal adhesion 1 DPP4
extracellular matrix 1 APOE
peroxisomal membrane 1 HMGCR
collagen-containing extracellular matrix 2 APOA1, APOE
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 2 DHCR7, PTGS2
Late endosome 1 PCSK9
receptor complex 2 ABCG5, ABCG8
neuron projection 1 PTGS2
phagocytic cup 1 TNF
Secreted, extracellular space 1 APOE
brush border membrane 1 NPC1L1
blood microparticle 2 APOA1, APOE
Endomembrane system 2 DPP4, NPC1L1
endosome lumen 2 APOB, INS
Lipid droplet 1 APOB
Cytoplasmic vesicle membrane 1 NPC1L1
Melanosome 1 APOE
myelin sheath 1 BCL2
Peroxisome membrane 1 HMGCR
secretory granule lumen 2 APOA1, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 7 APOA1, APOB, APOE, IL6, INS, PCSK9, PTGS2
endocytic vesicle 2 APOA1, DPP4
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
endoplasmic reticulum exit site 1 APOB
ATP-binding cassette (ABC) transporter complex 2 ABCG5, ABCG8
clathrin-coated endocytic vesicle membrane 2 APOB, APOE
synaptic cleft 1 APOE
endolysosome membrane 1 PCSK9
death-inducing signaling complex 1 CASP3
extrinsic component of external side of plasma membrane 1 PCSK9
discoidal high-density lipoprotein particle 1 APOE
spherical high-density lipoprotein particle 1 APOA1
lamellipodium membrane 1 DPP4
endocytic vesicle lumen 3 APOA1, APOB, APOE
PCSK9-LDLR complex 1 PCSK9
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
chylomicron remnant 2 APOB, APOE
intermediate-density lipoprotein particle 2 APOB, APOE
lipoprotein particle 1 APOE
multivesicular body, internal vesicle 1 APOE
mature chylomicron 1 APOB
Cell projection, lamellipodium membrane 1 DPP4
interleukin-6 receptor complex 1 IL6
Cell projection, invadopodium membrane 1 DPP4
PCSK9-AnxA2 complex 1 PCSK9
BAD-BCL-2 complex 1 BCL2
[Dipeptidyl peptidase 4 soluble form]: Secreted 1 DPP4
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Yu Chun Teng, Marie Claire Gielen, Nina M de Gruijter, Coziana Ciurtin, Elizabeth C Rosser, Kersti Karu. Phytosterols in human serum as measured using a liquid chromatography tandem mass spectrometry. The Journal of steroid biochemistry and molecular biology. 2024 Jul; 241(?):106519. doi: 10.1016/j.jsbmb.2024.106519. [PMID: 38614432]
  • Zhijie Qin, Yunliang Zhang, Song Liu, Weizhu Zeng, Jingwen Zhou, Sha Xu. Combining Metabolic Engineering and Lipid Droplet Assembly to Achieve Campesterol Overproduction in Saccharomyces cerevisiae. Journal of agricultural and food chemistry. 2024 Mar; 72(9):4814-4824. doi: 10.1021/acs.jafc.3c09764. [PMID: 38389392]
  • Jiarui Mi, Qingwei Jiang, Zhengwei Qi, Zhengye Liu, Xiaoyin Bai, Xia Zheng, Jiaguo Wu, Yanfei Fang, Aiming Yang, Haotian Chen. Plasma campesterol and ABCG5/ABCG8 gene loci on the risk of cholelithiasis and cholecystitis: evidence from Mendelian randomization and colocalization analyses. Human genomics. 2024 Feb; 18(1):19. doi: 10.1186/s40246-024-00583-y. [PMID: 38347599]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Shanhui Xu, Xiaoxuan Teng, Yanran Li. Optimization of Campesterol-Producing Yeast Strains as a Feasible Platform for the Functional Reconstitution of Plant Membrane-Bound Enzymes. ACS synthetic biology. 2023 Mar; ?(?):. doi: 10.1021/acssynbio.2c00599. [PMID: 36972300]
  • Ahmed Jibrin Uttu, Muhammad Sani Sallau, Hamisu Ibrahim, Ogunkemi Risikat Agbeke Iyun. In silico modelling and NMR Characterization of some steroids from Strychnos innocua (Delile) root bark as potential antifungal agents. Steroids. 2023 Mar; 194(?):109222. doi: 10.1016/j.steroids.2023.109222. [PMID: 36924816]
  • Valéria Sutti Nunes, Edite Vieira Silva de Campos, Jamal Baracat, Victor França, Érica Ivana Lázaro Gomes, Raissa Peres Coelho, Edna Regina Nakandakare, Vanessa Helena Souza Zago, Eliana Cotta de Faria, Eder Carlos Rocha Quintão. Plasma Campesterol Is Positively Associated with Carotid Plaques in Asymptomatic Subjects. International journal of molecular sciences. 2022 Oct; 23(19):. doi: 10.3390/ijms231911997. [PMID: 36233298]
  • S Baumgartner, D Lütjohann, C Husche, A Kerksiek, A K Groen, R P Mensink, J Plat. Plasma oxyphytosterols most likely originate from hepatic oxidation and subsequent spill-over in the circulation. The Journal of steroid biochemistry and molecular biology. 2022 02; 216(?):106039. doi: 10.1016/j.jsbmb.2021.106039. [PMID: 34861389]
  • Madlen Reinicke, Judith Leyh, Silke Zimmermann, Soroth Chey, Ilijana Begcevic Brkovic, Christin Wassermann, Julia Landmann, Dieter Lütjohann, Berend Isermann, Ingo Bechmann, Uta Ceglarek. Plant Sterol-Poor Diet Is Associated with Pro-Inflammatory Lipid Mediators in the Murine Brain. International journal of molecular sciences. 2021 Dec; 22(24):. doi: 10.3390/ijms222413207. [PMID: 34948003]
  • S Mashnafi, J Plat, R P Mensink, P J Joris, J P D Kleinloog, S Baumgartner. Effects of an 8-week aerobic exercise program on plasma markers for cholesterol absorption and synthesis in older overweight and obese men. Lipids in health and disease. 2021 Sep; 20(1):112. doi: 10.1186/s12944-021-01537-2. [PMID: 34548089]
  • Fabio Ferrini, Daniele Fraternale, Sabrina Donati Zeppa, Giancarlo Verardo, Andrea Gorassini, Vittoria Carrabs, Maria Cristina Albertini, Piero Sestili. Yield, Characterization, and Possible Exploitation of Cannabis Sativa L. Roots Grown under Aeroponics Cultivation. Molecules (Basel, Switzerland). 2021 Aug; 26(16):. doi: 10.3390/molecules26164889. [PMID: 34443479]
  • Teruo Jojima, Shintaro Sakurai, Sho Wakamatsu, Toshie Iijima, Masahiro Saito, Takuya Tomaru, Takahiko Kogai, Isao Usui, Yoshimasa Aso. Empagliflozin increases plasma levels of campesterol, a marker of cholesterol absorption, in patients with type 2 diabetes: Association with a slight increase in high-density lipoprotein cholesterol. International journal of cardiology. 2021 05; 331(?):243-248. doi: 10.1016/j.ijcard.2021.01.063. [PMID: 33556413]
  • Sławomira Drzymała-Czyż, Patrycja Krzyżanowska-Jankowska, Krzysztof Dziedzic, Aleksandra Lisowska, Szymon Kurek, Joanna Goździk-Spychalska, Victoria Kononets, Dagmara Woźniak, Edyta Mądry, Jarosław Walkowiak. Severe Genotype, Pancreatic Insufficiency and Low Dose of Pancreatic Enzymes Associate with Abnormal Serum Sterol Profile in Cystic Fibrosis. Biomolecules. 2021 02; 11(2):. doi: 10.3390/biom11020313. [PMID: 33669566]
  • Tabea Jahn, Christopher Clark, Anja Kerksiek, Piotr Lewczuk, Dieter Lütjohann, Julius Popp. Cholesterol metabolites and plant sterols in cerebrospinal fluid are associated with Alzheimer's cerebral pathology and clinical disease progression. The Journal of steroid biochemistry and molecular biology. 2021 01; 205(?):105785. doi: 10.1016/j.jsbmb.2020.105785. [PMID: 33171206]
  • Yujiro Nakano, Chikara Komiya, Hitomi Shimizu, Hiroyuki Mishima, Kumiko Shiba, Kazutaka Tsujimoto, Kenji Ikeda, Kenichi Kashimada, Sumito Dateki, Koh-Ichiro Yoshiura, Yoshihiro Ogawa, Tetsuya Yamada. A case of ezetimibe-effective hypercholesterolemia with a novel heterozygous variant in ABCG5. Endocrine journal. 2020 Nov; 67(11):1099-1105. doi: 10.1507/endocrj.ej20-0044. [PMID: 32641618]
  • Beibei Zhao, Yan Zhang, Hua Li, Jiawen Deng, Haodi Gong, Zhicheng Chen. Nutritional Component and Chemical Characterization of Chinese Highland Barley Bran Oil. Journal of oleo science. 2020 Nov; 69(11):1339-1347. doi: 10.5650/jos.ess19318. [PMID: 33055435]
  • Ivana Semova, Amy E Levenson, Joanna Krawczyk, Kevin Bullock, Kathryn A Williams, R Paul Wadwa, Philip R Khoury, Thomas R Kimball, Elaine M Urbina, Sarah D de Ferranti, David M Maahs, Lawrence M Dolan, Amy S Shah, Clary B Clish, Sudha B Biddinger. Markers of cholesterol synthesis are elevated in adolescents and young adults with type 2 diabetes. Pediatric diabetes. 2020 11; 21(7):1126-1131. doi: 10.1111/pedi.13097. [PMID: 32738021]
  • Takeru Koga, Takaiku Sakamoto, Eiji Sakuradani, Akihiro Tai. Neurite Outgrowth-Promoting Activity of Compounds in PC12 Cells from Sunflower Seeds. Molecules (Basel, Switzerland). 2020 Oct; 25(20):. doi: 10.3390/molecules25204748. [PMID: 33081156]
  • Ya Dan Qian, Si Yuan Tan, Gui Ru Dong, Yong Jie Niu, Ching Yuan Hu, Yong Hong Meng. Increased campesterol synthesis by improving lipid content in engineered Yarrowia lipolytica. Applied microbiology and biotechnology. 2020 Aug; 104(16):7165-7175. doi: 10.1007/s00253-020-10743-4. [PMID: 32592029]
  • Valéria Sutti Nunes, Isabela M Bensenor, Paulo A Lotufo, Marisa Passarelli, Edna Regina Nakandakare, Eder Carlos Rocha Quintão. The coronary artery calcium score is linked to plasma cholesterol synthesis and absorption markers: Brazilian Longitudinal Study of Adult Health. Bioscience reports. 2020 07; 40(7):. doi: 10.1042/bsr20201094. [PMID: 32579186]
  • Fang Liu, Xiaoping Zhang, Mingdao Wang, Lele Guo, Yingyue Yang, Mingqin Zhao. Biosorption of sterols from tobacco waste extract using living and dead of newly isolated fungus Aspergillus fumigatus strain LSD-1. Bioscience, biotechnology, and biochemistry. 2020 Jul; 84(7):1521-1528. doi: 10.1080/09168451.2020.1742089. [PMID: 32183612]
  • Josep M Llop-Talaveron, Elisabet Leiva-Badosa, Ana Novak, Raúl Rigo-Bonnin, Josep R Ticó-Grau, Josep M Suñé-Negre, Ana Suárez-Lledó, Toni Lozano-Andreu, Maria B Badía-Tahull. Phytosterolaemia associated with parenteral nutrition administration in adult patients. The British journal of nutrition. 2020 06; 123(12):1365-1372. doi: 10.1017/s0007114520000574. [PMID: 32077392]
  • Adchara Prommaban, Niramon Utama-Ang, Anan Chaikitwattana, Chairat Uthaipibull, John B Porter, Somdet Srichairatanakool. Phytosterol, Lipid and Phenolic Composition, and Biological Activities of Guava Seed Oil. Molecules (Basel, Switzerland). 2020 May; 25(11):. doi: 10.3390/molecules25112474. [PMID: 32471050]
  • Abdirahman Elmi, Rosella Spina, Arnaud Risler, Stéphanie Philippot, Ali Mérito, Raphaël E Duval, Fatouma Mohamed Abdoul-Latif, Dominique Laurain-Mattar. Evaluation of Antioxidant and Antibacterial Activities, Cytotoxicity of Acacia seyal Del Bark Extracts and Isolated Compounds. Molecules (Basel, Switzerland). 2020 May; 25(10):. doi: 10.3390/molecules25102392. [PMID: 32455580]
  • Asmita Poudel, George Gachumi, Ildiko Badea, Zafer Dallal Bashi, Anas El-Aneed. The simultaneous quantification of phytosterols and tocopherols in liposomal formulations using validated atmospheric pressure chemical ionization- liquid chromatography -tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2020 May; 183(?):113104. doi: 10.1016/j.jpba.2020.113104. [PMID: 32058287]
  • Cathelijne Heymans, Lara R Heij, Kaatje Lenaerts, Marcel den Dulk, Mhamed Hadfoune, Chantal van Heugten, Owen B Spiller, Michael L Beeton, Sarah J Stock, Alan H Jobe, Matthew S Payne, Matthew W Kemp, Boris W Kramer, Jogchum Plat, Wim G van Gemert, Tim G A M Wolfs. Prophylactic Intra-Uterine β-Cyclodextrin Administration during Intra-Uterine Ureaplasma parvum Infection Partly Prevents Liver Inflammation without Interfering with the Enterohepatic Circulation of the Fetal Sheep. Nutrients. 2020 May; 12(5):. doi: 10.3390/nu12051312. [PMID: 32380648]
  • Hiroshi Yoshida, Hayato Tada, Kumie Ito, Yoshimi Kishimoto, Hidekatsu Yanai, Tomonori Okamura, Katsunori Ikewaki, Kyoko Inagaki, Tetsuo Shoji, Hideaki Bujo, Takashi Miida, Masayuki Yoshida, Masafumi Kuzuya, Shizuya Yamashita. Reference Intervals of Serum Non-Cholesterol Sterols by Gender in Healthy Japanese Individuals. Journal of atherosclerosis and thrombosis. 2020 May; 27(5):409-417. doi: 10.5551/jat.50187. [PMID: 31484845]
  • Ivy W Chen, Robert J Grebenok, Hubert Schaller, Keyan Zhu-Salzman, Spencer T Behmer. Aphid growth and reproduction on plants with altered sterol profiles: Novel insights using Arabidopsis mutant and overexpression lines. Journal of insect physiology. 2020 May; 123(?):104054. doi: 10.1016/j.jinsphys.2020.104054. [PMID: 32275907]
  • Claudia Aparecida Silva Almeida, Sueli Regina Baggio, Lilian Regina Barros Mariutti, Neura Bragagnolo. One-step rapid extraction of phytosterols from vegetable oils. Food research international (Ottawa, Ont.). 2020 04; 130(?):108891. doi: 10.1016/j.foodres.2019.108891. [PMID: 32156349]
  • April Davis, Laura K Cole, Kevin Kyung-Jun Min, Sidney Chow, Patrick C Choy, David Mymin, Grant M Hatch. A Phytosterolemic Mixture of Sterols Inhibits Cholesterol Synthesis, Esterification, and Low-Density Lipoprotein Receptor mRNA Abundance in HepG2 Cells. Lipids. 2020 03; 55(2):193-198. doi: 10.1002/lipd.12223. [PMID: 32065674]
  • Paweł Górnaś, Magdalena Rudzińska, Anna Grygier, Pravin Kumar Sahu, Khageshwar Singh Patel. Tephrosia apollinea seed: a new rich source of essential polyunsaturated fatty acids, tocopherols, sterols, and squalene. Natural product research. 2020 Jan; 34(2):296-299. doi: 10.1080/14786419.2018.1525373. [PMID: 30406669]
  • Joon Hee Lee, Da Young Song, Sun-Hee Jun, Sang Hoon Song, Choong Ho Shin, Chang-Seok Ki, Kyunghoon Lee, Junghan Song. High prevalence of increased sitosterol levels in hypercholesterolemic children suggest underestimation of sitosterolemia incidence. PloS one. 2020; 15(8):e0238079. doi: 10.1371/journal.pone.0238079. [PMID: 32845916]
  • Manon Le Goff, Eric Le Ferrec, Claire Mayer, Virginie Mimouni, Dominique Lagadic-Gossmann, Benoît Schoefs, Lionel Ulmann. Microalgal carotenoids and phytosterols regulate biochemical mechanisms involved in human health and disease prevention. Biochimie. 2019 Dec; 167(?):106-118. doi: 10.1016/j.biochi.2019.09.012. [PMID: 31545993]
  • Atsuko Chihara, Atsushi Tanaka, Takeshi Morimoto, Mio Sakuma, Michio Shimabukuro, Takashi Nomiyama, Osamu Arasaki, Shinichiro Ueda, Koichi Node. Differences in lipid metabolism between anagliptin and sitagliptin in patients with type 2 diabetes on statin therapy: a secondary analysis of the REASON trial. Cardiovascular diabetology. 2019 11; 18(1):158. doi: 10.1186/s12933-019-0965-3. [PMID: 31733647]
  • Ulrich Pecks, Verena Bornemann, Anika Klein, Laura Segger, Nicolai Maass, Ibrahim Alkatout, Christel Eckmann-Scholz, Mohamed Elessawy, Dieter Lütjohann. Estimating fetal cholesterol synthesis rates by cord blood analysis in intrauterine growth restriction and normally grown fetuses. Lipids in health and disease. 2019 Oct; 18(1):185. doi: 10.1186/s12944-019-1117-1. [PMID: 31653257]
  • M A Nurseitova, F B Amutova, A A Zhakupbekova, A S Omarova, A B Kondybayev, G A Bayandy, N N Akhmetsadykov, B Faye, G S Konuspayeva. Comparative study of fatty acid and sterol profiles for the investigation of potential milk fat adulteration. Journal of dairy science. 2019 Sep; 102(9):7723-7733. doi: 10.3168/jds.2018-15620. [PMID: 31255261]
  • Stefania Giammarioli, Concetta Boniglia, Luigia Di Stasio, Raffaella Gargiulo, Maurizio Mosca, Brunella Carratù. Phytosterols in supplements containing Serenoa repens: an example of variability of active principles in commercial plant based products. Natural product research. 2019 Aug; 33(15):2257-2261. doi: 10.1080/14786419.2018.1490910. [PMID: 30295072]
  • Joon Hee Lee, Kyunghoon Lee, Sun Hee Jun, Sang Hoon Song, Choong Ho Shin, Junghan Song. A Multiplex Phytosterol Assay Utilizing Gas Chromatography-Mass Spectrometry for Diagnosis of Inherited Lipid Storage Disorders. Annals of laboratory medicine. 2019 Jul; 39(4):411-413. doi: 10.3343/alm.2019.39.4.411. [PMID: 30809990]
  • Maite M Schroor, Henriette P Sennels, Jan Fahrenkrug, Henrik L Jørgensen, Jogchum Plat, Ronald P Mensink. Diurnal Variation of Markers for Cholesterol Synthesis, Cholesterol Absorption, and Bile Acid Synthesis: A Systematic Review and the Bispebjerg Study of Diurnal Variations. Nutrients. 2019 Jun; 11(7):. doi: 10.3390/nu11071439. [PMID: 31247945]
  • Dieter Lütjohann, Ingemar Björkhem, Silvia Friedrichs, Anja Kerksiek, Anita Lövgren-Sandblom, Wolf-Jochen Geilenkeuser, Robert Ahrends, Isabel Andrade, Diana Ansorena, Iciar Astiasarán, Lucía Baila-Rueda, Bianca Barriuso, Susen Becker, Lionel Bretillon, Richard W Browne, Claudio Caccia, Uta Ceglarek, Ana Cenarro, Peter J Crick, Günter Fauler, Guadalupe Garcia-Llatas, Robert Gray, William J Griffiths, Helena Gylling, Scott Harding, Christin Helmschrodt, Luigi Iuliano, Hans-Gerd Janssen, Peter Jones, Leena Kaipiainen, Frank Kannenberg, María Jesús Lagarda, Valerio Leoni, Ana Maria Lottenberg, Dylan S MacKay, Silke Matysik, Jeff McDonald, Maria Menendez-Carreño, Semone B Myrie, Valéria Sutti Nunes, Richard E Ostlund, Eliana Polisecki, Fernando Ramos, Todd C Rideout, Ernst J Schaefer, Gerd Schmitz, Yuqin Wang, Chiara Zerbinati, Ulf Diczfalusy, Hans-Frieder Schött. First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography-Urgent need for harmonisation of analytical methods. The Journal of steroid biochemistry and molecular biology. 2019 06; 190(?):115-125. doi: 10.1016/j.jsbmb.2019.03.025. [PMID: 30940596]
  • Valéria Sutti Nunes, Patrícia Miralda Cazita, Sérgio Catanozi, Edna Regina Nakandakare, Eder Carlos Rocha Quintão. Phytosterol containing diet increases plasma and whole body concentration of phytosterols in apoE-KO but not in LDLR-KO mice. Journal of bioenergetics and biomembranes. 2019 04; 51(2):131-136. doi: 10.1007/s10863-019-09786-8. [PMID: 30739226]
  • Ahmed Adebayo Ishola, Kayode Ezekiel Adewole. Phytosterols and triterpenes from Morinda lucida Benth. exhibit binding tendency against class I HDAC and HDAC7 isoforms. Molecular biology reports. 2019 Apr; 46(2):2307-2325. doi: 10.1007/s11033-019-04689-8. [PMID: 30771146]
  • Sultan Mashnafi, Jogchum Plat, Ronald P Mensink, Sabine Baumgartner. Non-Cholesterol Sterol Concentrations as Biomarkers for Cholesterol Absorption and Synthesis in Different Metabolic Disorders: A Systematic Review. Nutrients. 2019 Jan; 11(1):. doi: 10.3390/nu11010124. [PMID: 30634478]
  • Moacir Guimarães de Melo, Brina Aguiar da Silva, Gilcllys de Souza Costa, João Cândido André da Silva Neto, Patrícia Kaori Soares, Adalberto Luis Val, Jamal da Silva Chaar, Hector Henrique Ferreira Koolen, Giovana Anceski Bataglion. Sewage contamination of Amazon streams crossing Manaus (Brazil) by sterol biomarkers. Environmental pollution (Barking, Essex : 1987). 2019 Jan; 244(?):818-826. doi: 10.1016/j.envpol.2018.10.055. [PMID: 30390455]
  • Xiaohui Zhao, Banmacailang Dong, Pi Li, Wei Wei, Jun Dang, Zenggeng Liu, Yanduo Tao, Hongping Han, Yun Shao, Huilan Yue. Fatty Acid and Phytosterol Composition, and Biological Activities of Lycium ruthenicum Murr. Seed Oil. Journal of food science. 2018 Oct; 83(10):2448-2456. doi: 10.1111/1750-3841.14328. [PMID: 30178878]
  • Valéria Sutti Nunes, Patrícia Miralda Cazita, Sérgio Catanozi, Edna Regina Nakandakare, Eder Carlos Rocha Quintão. Decreased content, rate of synthesis and export of cholesterol in the brain of apoE knockout mice. Journal of bioenergetics and biomembranes. 2018 08; 50(4):283-287. doi: 10.1007/s10863-018-9757-9. [PMID: 29675736]
  • Helena E Miettinen, Kristiina Rönö, Saila B Koivusalo, Johan G Eriksson, Helena Gylling. Effect of gestational diabetes mellitus on newborn cholesterol metabolism. Atherosclerosis. 2018 08; 275(?):346-351. doi: 10.1016/j.atherosclerosis.2018.06.879. [PMID: 30015298]
  • Hans-Frieder Schött, Sabrina Krautbauer, Marcus Höring, Gerhard Liebisch, Silke Matysik. A Validated, Fast Method for Quantification of Sterols and Gut Microbiome Derived 5α/β-Stanols in Human Feces by Isotope Dilution LC-High-Resolution MS. Analytical chemistry. 2018 07; 90(14):8487-8494. doi: 10.1021/acs.analchem.8b01278. [PMID: 29920210]
  • Rajapandiyan Krishnamoorthy, Jegan Athinarayanan, Vaiyapuri Subbarayan Periasamy, Abdulraheem R Adisa, Mohammed A Al-Shuniaber, Mustafa A Gassem, Ali A Alshatwi. Antimicrobial activity of nanoemulsion on drug-resistant bacterial pathogens. Microbial pathogenesis. 2018 Jul; 120(?):85-96. doi: 10.1016/j.micpath.2018.04.035. [PMID: 29684541]
  • Nini H Sissener, Grethe Rosenlund, Ingunn Stubhaug, Nina S Liland. Tissue sterol composition in Atlantic salmon (Salmo salar L.) depends on the dietary cholesterol content and on the dietary phytosterol:cholesterol ratio, but not on the dietary phytosterol content. The British journal of nutrition. 2018 03; 119(6):599-609. doi: 10.1017/s0007114517003853. [PMID: 29397797]
  • Yuguang Lin, Diny Knol, María Menéndez-Carreño, Raymond Baris, Hans-Gerd Janssen, Elke A Trautwein. Oxidation of sitosterol and campesterol in foods upon cooking with liquid margarines without and with added plant sterol esters. Food chemistry. 2018 Feb; 241(?):387-396. doi: 10.1016/j.foodchem.2017.08.118. [PMID: 28958544]
  • Andrea Alvarez-Sala, Gabriel López-García, Alessandro Attanzio, Luisa Tesoriere, Antonio Cilla, Reyes Barberá, Amparo Alegría. Effects of Plant Sterols or β-Cryptoxanthin at Physiological Serum Concentrations on Suicidal Erythrocyte Death. Journal of agricultural and food chemistry. 2018 Feb; 66(5):1157-1166. doi: 10.1021/acs.jafc.7b05575. [PMID: 29345907]
  • Islam J A Hamdan, Lorena Claumarchirant, Guadalupe Garcia-Llatas, Amparo Alegría, María Jesús Lagarda. Sterols in infant formulas: validation of a gas chromatographic method. International journal of food sciences and nutrition. 2017 Sep; 68(6):695-703. doi: 10.1080/09637486.2017.1287883. [PMID: 28276904]
  • Nam Hee Choi, Ja Yeong Jang, Gyung Ja Choi, Yong Ho Choi, Kyoung Soo Jang, Van Thu Nguyen, Byung-Sun Min, Quang Le Dang, Jin-Cheol Kim. Antifungal activity of sterols and dipsacus saponins isolated from Dipsacus asper roots against phytopathogenic fungi. Pesticide biochemistry and physiology. 2017 Sep; 141(?):103-108. doi: 10.1016/j.pestbp.2016.12.006. [PMID: 28911735]
  • Maryam Shamloo, Elizabeth A Babawale, Agnelo Furtado, Robert J Henry, Peter K Eck, Peter J H Jones. Effects of genotype and temperature on accumulation of plant secondary metabolites in Canadian and Australian wheat grown under controlled environments. Scientific reports. 2017 08; 7(1):9133. doi: 10.1038/s41598-017-09681-5. [PMID: 28831148]
  • Karen Jaceldo-Siegl, Dieter Lütjohann, Rawiwan Sirirat, Andrew Mashchak, Gary E Fraser, Ella Haddad. Variations in dietary intake and plasma concentrations of plant sterols across plant-based diets among North American adults. Molecular nutrition & food research. 2017 08; 61(8):. doi: 10.1002/mnfr.201600828. [PMID: 28130879]
  • Maria Hukkinen, Annika Mutanen, Markku Nissinen, Laura Merras-Salmio, Helena Gylling, Mikko P Pakarinen. Parenteral Plant Sterols Accumulate in the Liver Reflecting Their Increased Serum Levels and Portal Inflammation in Children With Intestinal Failure. JPEN. Journal of parenteral and enteral nutrition. 2017 08; 41(6):1014-1022. doi: 10.1177/0148607116637855. [PMID: 26962062]
  • Xing Lin Ho, Wai Mun Loke. Dietary Plant Sterols Supplementation Increases In Vivo Nitrite and Nitrate Production in Healthy Adults: A Randomized, Controlled Study. Journal of food science. 2017 Jul; 82(7):1750-1756. doi: 10.1111/1750-3841.13752. [PMID: 28708316]
  • Akinori Sawamura, Takahiro Okumura, Hiroaki Hiraiwa, Soichiro Aoki, Toru Kondo, Takeo Ichii, Kenji Furusawa, Naoki Watanabe, Naoaki Kano, Kenji Fukaya, Ryota Morimoto, Yasuko K Bando, Toyoaki Murohara. Cholesterol metabolism as a prognostic marker in patients with mildly symptomatic nonischemic dilated cardiomyopathy. Journal of cardiology. 2017 Jun; 69(6):888-894. doi: 10.1016/j.jjcc.2016.08.012. [PMID: 27686044]
  • Oliver Weingärtner, Ivan Bogeski, Carsten Kummerow, Stephan H Schirmer, Constanze Husche, Tim Vanmierlo, Gudrun Wagenpfeil, Markus Hoth, Michael Böhm, Dieter Lütjohann, Ulrich Laufs. Plant sterol ester diet supplementation increases serum plant sterols and markers of cholesterol synthesis, but has no effect on total cholesterol levels. The Journal of steroid biochemistry and molecular biology. 2017 05; 169(?):219-225. doi: 10.1016/j.jsbmb.2016.07.016. [PMID: 27473562]
  • Blanca Barriuso, Diana Ansorena, Iciar Astiasarán. Oxysterols formation: A review of a multifactorial process. The Journal of steroid biochemistry and molecular biology. 2017 05; 169(?):39-45. doi: 10.1016/j.jsbmb.2016.02.027. [PMID: 26921766]
  • Sabine Baumgartner, Ronald P Mensink, Els De Smet, Maurice Konings, Susana Fuentes, Willem M de Vos, Jogchum Plat. Effects of plant stanol ester consumption on fasting plasma oxy(phyto)sterol concentrations as related to fecal microbiota characteristics. The Journal of steroid biochemistry and molecular biology. 2017 05; 169(?):46-53. doi: 10.1016/j.jsbmb.2016.02.029. [PMID: 26940357]
  • Frans Stellaard, Klaus von Bergmann, Thomas Sudhop, Dieter Lütjohann. The value of surrogate markers to monitor cholesterol absorption, synthesis and bioconversion to bile acids under lipid lowering therapies. The Journal of steroid biochemistry and molecular biology. 2017 05; 169(?):111-122. doi: 10.1016/j.jsbmb.2016.03.030. [PMID: 27060336]
  • Norma Elizabeth Moreno-Anzúrez, Silvia Marquina, Laura Alvarez, Alejandro Zamilpa, Patricia Castillo-España, Irene Perea-Arango, Pilar Nicasio Torres, Maribel Herrera-Ruiz, Edgar Rolando Díaz García, Jaime Tortoriello García, Jesús Arellano-García. A Cytotoxic and Anti-inflammatory Campesterol Derivative from Genetically Transformed Hairy Roots of Lopezia racemosa Cav. (Onagraceae). Molecules (Basel, Switzerland). 2017 Jan; 22(1):. doi: 10.3390/molecules22010118. [PMID: 28085103]
  • S De Vuono, M A Ricci, D Siepi, M Boni, A Gentili, M Scavizzi, G Daviddi, P Labate, A R Roscini, G Lupattelli. Laparoscopic sleeve gastrectomy modifies cholesterol synthesis but not cholesterol absorption. Obesity research & clinical practice. 2017 Jan; 11(1):118-122. doi: 10.1016/j.orcp.2016.12.004. [PMID: 28057416]
  • Zahra Amri, Houda Lazreg-Aref, Manel Mekni, Sinda El-Gharbi, Olfa Dabbaghi, Beligh Mechri, Mohamed Hammami. Oil Characterization and Lipids Class Composition of Pomegranate Seeds. BioMed research international. 2017; 2017(?):2037341. doi: 10.1155/2017/2037341. [PMID: 28812011]
  • Doyun Kim, Jung Bae Park, Woong-Kee Choi, Seung Jun Lee, Ilho Lim, Soo Kyung Bae. Simultaneous determination of β-sitosterol, campesterol, and stigmasterol in rat plasma by using LC-APCI-MS/MS: Application in a pharmacokinetic study of a titrated extract of the unsaponifiable fraction of Zea mays L. Journal of separation science. 2016 Nov; 39(21):4060-4070. doi: 10.1002/jssc.201600589. [PMID: 27591043]
  • Begoña Miras-Moreno, Ana Belén Sabater-Jara, M A Pedreño, Lorena Almagro. Bioactivity of Phytosterols and Their Production in Plant in Vitro Cultures. Journal of agricultural and food chemistry. 2016 Sep; 64(38):7049-58. doi: 10.1021/acs.jafc.6b02345. [PMID: 27615454]
  • Monica Gelzo, Concetta Sica, Ausilia Elce, Antonio Dello Russo, Paola Iacotucci, Vincenzo Carnovale, Valeria Raia, Donatello Salvatore, Gaetano Corso, Giuseppe Castaldo. Reduced absorption and enhanced synthesis of cholesterol in patients with cystic fibrosis: a preliminary study of plasma sterols. Clinical chemistry and laboratory medicine. 2016 Sep; 54(9):1461-6. doi: 10.1515/cclm-2015-1151. [PMID: 26913457]
  • Fumiaki Okahara, Junko Suzuki, Kohjiro Hashizume, Noriko Osaki, Akira Shimotoyodome. Triterpene alcohols and sterols from rice bran reduce postprandial hyperglycemia in rodents and humans. Molecular nutrition & food research. 2016 07; 60(7):1521-31. doi: 10.1002/mnfr.201500897. [PMID: 26935127]
  • Paweł Górnaś, Magdalena Rudzińska, Marianna Raczyk, Arianne Soliven. Lipophilic bioactive compounds in the oils recovered from cereal by-products. Journal of the science of food and agriculture. 2016 Jul; 96(9):3256-65. doi: 10.1002/jsfa.7511. [PMID: 26522347]
  • Piia Simonen, Jukka Lehtonen, Helena Gylling, Markku Kupari. Cholesterol metabolism in cardiac sarcoidosis. Atherosclerosis. 2016 May; 248(?):210-5. doi: 10.1016/j.atherosclerosis.2016.03.018. [PMID: 27035112]
  • Yuki Tsukagoshi, Hideyuki Suzuki, Hikaru Seki, Toshiya Muranaka, Kiyoshi Ohyama, Yoshinori Fujimoto. Ajuga Δ24-Sterol Reductase Catalyzes the Direct Reductive Conversion of 24-Methylenecholesterol to Campesterol. The Journal of biological chemistry. 2016 Apr; 291(15):8189-98. doi: 10.1074/jbc.m115.703470. [PMID: 26872973]
  • R T Ras, W P Koppenol, U Garczarek, A Otten-Hofman, D Fuchs, F Wagner, E A Trautwein. Increases in plasma plant sterols stabilize within four weeks of plant sterol intake and are independent of cholesterol metabolism. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2016 Apr; 26(4):302-9. doi: 10.1016/j.numecd.2015.11.007. [PMID: 26806045]
  • Blanca Barriuso, Iciar Astiasarán, Diana Ansorena. Unsaturated lipid matrices protect plant sterols from degradation during heating treatment. Food chemistry. 2016 Apr; 196(?):451-8. doi: 10.1016/j.foodchem.2015.09.074. [PMID: 26593514]
  • Aline Coqueiro, Young H Choi, Robert Verpoorte, Karthick B S S Gupta, Maria De Mieri, Matthias Hamburger, Maria C M Young, Paul Stapleton, Simon Gibbons, Vanderlan da S Bolzani. Antistaphylococcal Prenylated Acylphoroglucinol and Xanthones from Kielmeyera variabilis. Journal of natural products. 2016 Mar; 79(3):470-6. doi: 10.1021/acs.jnatprod.5b00858. [PMID: 26900954]
  • Isabel Andrade, Lèlita Santos, Fernando Ramos. Cholesterol absorption and synthesis markers in Portuguese hypercholesterolemic adults: A cross-sectional study. European journal of internal medicine. 2016 Mar; 28(?):85-90. doi: 10.1016/j.ejim.2015.10.022. [PMID: 26577223]
  • Nobusuke Kishikawa, Keishi Kanno, Akiko Sugiyama, Kenichi Yokobayashi, Masafumi Mizooka, Susumu Tazuma. Long-term administration of a Niemann-Pick C1-like 1 inhibitor, ezetimibe, does not worsen bile lithogenicity in dyslipidemic patients with hepatobiliary diseases. Journal of hepato-biliary-pancreatic sciences. 2016 Feb; 23(2):125-31. doi: 10.1002/jhbp.313. [PMID: 26692575]
  • Shasha Deng, Ting Wei, Kunling Tan, Mingyu Hu, Fang Li, Yunlan Zhai, Shue Ye, Yuehua Xiao, Lei Hou, Yan Pei, Ming Luo. Phytosterol content and the campesterol:sitosterol ratio influence cotton fiber development: role of phytosterols in cell elongation. Science China. Life sciences. 2016 Feb; 59(2):183-93. doi: 10.1007/s11427-015-4992-3. [PMID: 26803301]
  • Silvia Vaghini, Antonio Cilla, Guadalupe Garcia-Llatas, María Jesús Lagarda. Bioaccessibility study of plant sterol-enriched fermented milks. Food & function. 2016 Jan; 7(1):110-7. doi: 10.1039/c5fo00458f. [PMID: 26447847]
  • Hao-Xing Du, Wen-Hai Xiao, Ying Wang, Xiao Zhou, Yu Zhang, Duo Liu, Ying-Jin Yuan. Engineering Yarrowia lipolytica for Campesterol Overproduction. PloS one. 2016; 11(1):e0146773. doi: 10.1371/journal.pone.0146773. [PMID: 26751680]
  • Ana Beatriz Zanqui, Damila Rodrigues de Morais, Claudia Marques da Silva, Jandyson Machado Santos, Sandra Terezinha Marques Gomes, Jesuí Vergílio Visentainer, Marcos Nogueira Eberlin, Lúcio Cardozo-Filho, Makoto Matsushita. Subcritical extraction of flaxseed oil with n-propane: Composition and purity. Food chemistry. 2015 Dec; 188(?):452-8. doi: 10.1016/j.foodchem.2015.05.033. [PMID: 26041217]
  • Haixiang Zhao, Yongli Wang, Xiuli Xu, Heling Ren, Li Li, Li Xiang, Weike Zhong. Detection of Adulterated Vegetable Oils Containing Waste Cooking Oils Based on the Contents and Ratios of Cholesterol, β-Sitosterol, and Campesterol by Gas Chromatography/Mass Spectrometry. Journal of AOAC International. 2015 Nov; 98(6):1645-54. doi: 10.5740/jaoacint.15-053. [PMID: 26651578]
  • David A Mannock, Matthew G K Benesch, Ruthven N A H Lewis, Ronald N McElhaney. A comparative calorimetric and spectroscopic study of the effects of cholesterol and of the plant sterols β-sitosterol and stigmasterol on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine bilayer membranes. Biochimica et biophysica acta. 2015 Aug; 1848(8):1629-38. doi: 10.1016/j.bbamem.2015.04.009. [PMID: 25911208]
  • Alexandra Luister, Hans Frieder Schött, Constanze Husche, Hans-Joachim Schäfers, Michael Böhm, Jogchum Plat, Stefan Gräber, Dieter Lütjohann, Ulrich Laufs, Oliver Weingärtner. Increased plant sterol deposition in vascular tissue characterizes patients with severe aortic stenosis and concomitant coronary artery disease. Steroids. 2015 Jul; 99(Pt B):272-80. doi: 10.1016/j.steroids.2015.03.011. [PMID: 25814070]
  • Hans-Frieder Schött, Dieter Lütjohann. Validation of an isotope dilution gas chromatography-mass spectrometry method for combined analysis of oxysterols and oxyphytosterols in serum samples. Steroids. 2015 Jul; 99(Pt B):139-50. doi: 10.1016/j.steroids.2015.02.006. [PMID: 25701095]
  • Sabine Baumgartner, Ronald P Mensink, Maurice Konings, Hans-F Schött, Silvia Friedrichs, Constanze Husche, Dieter Lütjohann, Jogchum Plat. Postprandial plasma oxyphytosterol concentrations after consumption of plant sterol or stanol enriched mixed meals in healthy subjects. Steroids. 2015 Jul; 99(Pt B):281-6. doi: 10.1016/j.steroids.2015.01.017. [PMID: 25656784]
  • Ahmed A Saeed, Guillem Genové, Tian Li, Frank Hülshorst, Christer Betsholtz, Ingemar Björkhem, Dieter Lütjohann. Increased flux of the plant sterols campesterol and sitosterol across a disrupted blood brain barrier. Steroids. 2015 Jul; 99(Pt B):183-8. doi: 10.1016/j.steroids.2015.02.005. [PMID: 25683892]
  • Daniela M T Malina, Francisco A Fonseca, Sílvio A Barbosa, Soraia H Kasmas, Valéria A Machado, Carolina N França, Ney C Borges, Ronilson A Moreno, Maria C Izar. Additive effects of plant sterols supplementation in addition to different lipid-lowering regimens. Journal of clinical lipidology. 2015 Jul; 9(4):542-52. doi: 10.1016/j.jacl.2015.04.003. [PMID: 26228672]
  • Fredrik Rosqvist, Annika Smedman, Helena Lindmark-Månsson, Marie Paulsson, Paul Petrus, Sara Straniero, Mats Rudling, Ingrid Dahlman, Ulf Risérus. Potential role of milk fat globule membrane in modulating plasma lipoproteins, gene expression, and cholesterol metabolism in humans: a randomized study. The American journal of clinical nutrition. 2015 Jul; 102(1):20-30. doi: 10.3945/ajcn.115.107045. [PMID: 26016870]
  • Azadeh Hamedi, Amir Ghanbari, Razieh Razavipour, Vahid Saeidi, Mohammad M Zarshenas, Maryam Sohrabpour, Hassan Azari. Alyssum homolocarpum seeds: phytochemical analysis and effects of the seed oil on neural stem cell proliferation and differentiation. Journal of natural medicines. 2015 Jul; 69(3):387-96. doi: 10.1007/s11418-015-0905-9. [PMID: 25860174]
  • Rouyanne T Ras, Dagmar Fuchs, Wieneke P Koppenol, Ursula Garczarek, Arno Greyling, Christian Keicher, Carole Verhoeven, Hakim Bouzamondo, Frank Wagner, Elke A Trautwein. The effect of a low-fat spread with added plant sterols on vascular function markers: results of the Investigating Vascular Function Effects of Plant Sterols (INVEST) study. The American journal of clinical nutrition. 2015 Apr; 101(4):733-41. doi: 10.3945/ajcn.114.102053. [PMID: 25809853]
  • Panawan Suttiarporn, Watcharapong Chumpolsri, Sugunya Mahatheeranont, Suwaporn Luangkamin, Somsuda Teepsawang, Vijittra Leardkamolkarn. Structures of phytosterols and triterpenoids with potential anti-cancer activity in bran of black non-glutinous rice. Nutrients. 2015 Mar; 7(3):1672-87. doi: 10.3390/nu7031672. [PMID: 25756784]
  • Kevin Grosjean, Sébastien Mongrand, Laurent Beney, Françoise Simon-Plas, Patricia Gerbeau-Pissot. Differential effect of plant lipids on membrane organization: specificities of phytosphingolipids and phytosterols. The Journal of biological chemistry. 2015 Feb; 290(9):5810-25. doi: 10.1074/jbc.m114.598805. [PMID: 25575593]
  • Kazutaka Aoki, Takahiro Ijima, Hiroshi Kamiyama, Kazunari Kamiko, Yasuo Terauchi. Anagliptin decreases serum lathosterol level in patients with type 2 diabetes: a pilot study. Expert opinion on pharmacotherapy. 2015; 16(12):1749-54. doi: 10.1517/14656566.2015.1057120. [PMID: 26098722]
  • Xiaobo Lin, Susan B Racette, Lina Ma, Michael Wallendorf, Catherine Anderson Spearie, Richard E Ostlund. Plasma biomarker of dietary phytosterol intake. PloS one. 2015; 10(2):e0116912. doi: 10.1371/journal.pone.0116912. [PMID: 25668184]
  • Isabel Mendiara, Karim Bentayeb, Cristina Nerín, Celia Domeño. Online solid-phase extraction-liquid chromatography-mass spectrometry to determine free sterols in human serum. Talanta. 2015 Jan; 132(?):690-7. doi: 10.1016/j.talanta.2014.10.029. [PMID: 25476366]
  • Eric J Niesor, David Kallend, Darren Bentley, John J P Kastelein, G Kees Hovingh, Erik S G Stroes. Treatment of low HDL-C subjects with the CETP modulator dalcetrapib increases plasma campesterol only in those without ABCA1 and/or ApoA1 mutations. Lipids. 2014 Dec; 49(12):1245-9. doi: 10.1007/s11745-014-3956-x. [PMID: 25281277]
  • K Kannisto, S Rehnmark, K Slätis, P Webb, L Larsson, M Gåfvels, G Eggertsen, P Parini. The thyroid receptor β modulator GC-1 reduces atherosclerosis in ApoE deficient mice. Atherosclerosis. 2014 Dec; 237(2):544-54. doi: 10.1016/j.atherosclerosis.2014.09.035. [PMID: 25463087]