Cholesterol (BioDeep_00000003587)

 

Secondary id: BioDeep_00000337689, BioDeep_00000860104

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite natural product BioNovoGene_Lab2019


代谢物信息卡片


(1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol

化学式: C27H46O (386.3548)
中文名称: 胆固醇
谱图信息: 最多检出来源 Homo sapiens(plant) 12.81%

Reviewed

Last reviewed on 2024-06-29.

Cite this Page

Cholesterol. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/cholesterol (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000003587). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1[C@@H](CC2=CC[C@@H]3[C@@H]([C@]2(C1)C)CC[C@]1([C@H]3CC[C@@H]1[C@@H](CCCC(C)C)C)C)O
InChI: InChI=1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

描述信息

Cholesterol is a sterol (a combination steroid and alcohol) and a lipid found in the cell membranes of all body tissues and transported in the blood plasma of all animals. The name originates from the Greek chole- (bile) and stereos (solid), and the chemical suffix -ol for an alcohol. This is because researchers first identified cholesterol in solid form in gallstones in 1784. In the body, cholesterol can exist in either the free form or as an ester with a single fatty acid (of 10-20 carbons in length) covalently attached to the hydroxyl group at position 3 of the cholesterol ring. Due to the mechanism of synthesis, plasma cholesterol esters tend to contain relatively high proportions of polyunsaturated fatty acids. Most of the cholesterol consumed as a dietary lipid exists as cholesterol esters. Cholesterol esters have a lower solubility in water than cholesterol and are more hydrophobic. They are hydrolyzed by the pancreatic enzyme cholesterol esterase to produce cholesterol and free fatty acids. Cholesterol has vital structural roles in membranes and in lipid metabolism in general. It is a biosynthetic precursor of bile acids, vitamin D, and steroid hormones (glucocorticoids, estrogens, progesterones, androgens and aldosterone). In addition, it contributes to the development and functioning of the central nervous system, and it has major functions in signal transduction and sperm development. Cholesterol is a ubiquitous component of all animal tissues where much of it is located in the membranes, although it is not evenly distributed. The highest proportion of unesterified cholesterol is in the plasma membrane (roughly 30-50\\\\% of the lipid in the membrane or 60-80\\\\% of the cholesterol in the cell), while mitochondria and the endoplasmic reticulum have very low cholesterol contents. Cholesterol is also enriched in early and recycling endosomes, but not in late endosomes. The brain contains more cholesterol than any other organ where it comprises roughly a quarter of the total free cholesterol in the human body. Of all the organic constituents of blood, only glucose is present in a higher molar concentration than cholesterol. Cholesterol esters appear to be the preferred form for transport in plasma and as a biologically inert storage (de-toxified) form. They do not contribute to membranes but are packed into intracellular lipid particles. Cholesterol molecules (i.e. cholesterol esters) are transported throughout the body via lipoprotein particles. The largest lipoproteins, which primarily transport fats from the intestinal mucosa to the liver, are called chylomicrons. They carry mostly triglyceride fats and cholesterol that are from food, especially internal cholesterol secreted by the liver into the bile. In the liver, chylomicron particles give up triglycerides and some cholesterol. They are then converted into low-density lipoprotein (LDL) particles, which carry triglycerides and cholesterol on to other body cells. In healthy individuals, the LDL particles are large and relatively few in number. In contrast, large numbers of small LDL particles are strongly associated with promoting atheromatous disease within the arteries. (Lack of information on LDL particle number and size is one of the major problems of conventional lipid tests.). In conditions with elevated concentrations of oxidized LDL particles, especially small LDL particles, cholesterol promotes atheroma plaque deposits in the walls of arteries, a condition known as atherosclerosis, which is a major contributor to coronary heart disease and other forms of cardiovascular disease. There is a worldwide trend to believe that lower total cholesterol levels tend to correlate with lower atherosclerosis event rates (though some studies refute this idea). As a result, cholesterol has become a very large focus for the scientific community trying to determine the proper amount of cholesterol needed in a healthy diet. However, the primary association of atherosclerosis with c...
Constituent either free or as esters, of fish liver oils, lard, dairy fats, egg yolk and bran
Cholesterol is the major sterol in mammals. It is making up 20-25\\% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins[1][2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist[3].
Cholesterol is the major sterol in mammals. It is making up 20-25\% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins[1][2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist[3].

同义名列表

36 个代谢物同义名

(1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol; (3beta,14beta,17alpha)-Cholest-5-en-3-ol; (3Β,14β,17α)-cholest-5-en-3-ol; (3b,14b,17a)-Cholest-5-en-3-ol; 3beta-Hydroxycholest-5-ene; (3beta)-Cholest-5-en-3-ol; delta5-Cholesten-3beta-ol; 3Β-hydroxycholest-5-ene; 5:6-Cholesten-3beta-ol; (3Β)-cholest-5-en-3-ol; Cholest-5-en-3beta-ol; Cholesteryl alcohol; 5:6-Cholesten-3β-ol; Δ5-Cholesten-3β-ol; Cholesterol base H; Cholest-5-en-3β-ol; Cholest-5-en-3b-ol; Cholest-5-en-3-ol; (-)-Cholesterol; Super hartolan; Cholesterine; Cholesterin; Cholesterol; Cholestrol; Cholestrin; Hydrocerin; Fancol CH; Cordulan; Dusoline; Dusoran; Tegolan; Kathro; Dastar; Dythol; Lanol; Cholesterol



数据库引用编号

27 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(37)

BioCyc(9)

PlantCyc(3)

代谢反应

1006 个相关的代谢反应过程信息。

Reactome(671)

BioCyc(27)

WikiPathways(25)

Plant Reactome(5)

INOH(3)

PlantCyc(162)

COVID-19 Disease Map(0)

PathBank(113)

PharmGKB(0)

1628 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 ACE, CASP3, NOS3, PRL
Peripheral membrane protein 1 LPL
Endosome membrane 1 LDLR
Endoplasmic reticulum membrane 1 ABCA1
Nucleus 4 CASP3, NOS3, PLTP, PRL
cytosol 3 APOA2, CASP3, NOS3
phagocytic vesicle 1 ABCA1
nucleoplasm 3 CASP3, NOS3, PRL
RNA polymerase II transcription regulator complex 1 PRL
Cell membrane 6 ABCA1, ACE, LDLR, LPL, SELE, VCAM1
Multi-pass membrane protein 1 ABCA1
cell surface 4 ICAM1, LDLR, LPL, VCAM1
glutamatergic synapse 1 CASP3
Golgi apparatus 4 ABCA1, LDLR, NOS3, VCAM1
Golgi membrane 1 NOS3
neuronal cell body 1 CASP3
sarcolemma 1 VCAM1
Lysosome 3 ACE, LDLR, NPC2
endosome 2 ABCA1, ACE
plasma membrane 10 ABCA1, ACE, ICAM1, LDLR, LPL, NOS3, PRSS8, REN, SELE, VCAM1
Membrane 6 ABCA1, ACE, ICAM1, LDLR, REN, VCAM1
basolateral plasma membrane 2 ABCA1, LDLR
caveola 2 NOS3, SELE
extracellular exosome 9 ACE, APOA2, APOC3, ICAM1, NPC2, PRSS8, SHBG, VCAM1, VWF
endoplasmic reticulum 3 NPC2, VCAM1, VWF
extracellular space 15 ACE, APOA2, APOC3, ICAM1, IGF1, LPL, NPC2, PLTP, PRL, PRSS8, PTH, REN, SELE, VCAM1, VWF
lysosomal lumen 1 NPC2
perinuclear region of cytoplasm 3 ABCA1, NOS3, SELE
intracellular membrane-bounded organelle 1 ABCA1
filopodium 1 VCAM1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 5 ACE, ICAM1, LDLR, SELE, VCAM1
Secreted 11 ACE, APOA2, APOC3, IGF1, LPL, NPC2, PLTP, PRL, REN, SHBG, VWF
extracellular region 13 ACE, APOA2, APOC3, IGF1, LPL, NPC2, PLTP, PRL, PRSS8, PTH, REN, SHBG, VWF
Single-pass membrane protein 1 LDLR
Extracellular side 1 LPL
external side of plasma membrane 6 ABCA1, ACE, ICAM1, LDLR, SELE, VCAM1
Secreted, extracellular space, extracellular matrix 2 LPL, VWF
chylomicron 3 APOA2, APOC3, LPL
high-density lipoprotein particle 2 APOA2, PLTP
low-density lipoprotein particle 1 LDLR
very-low-density lipoprotein particle 3 APOA2, APOC3, LPL
Cytoplasm, P-body 1 NOS3
P-body 1 NOS3
Early endosome 4 APOA2, APOC3, LDLR, VCAM1
Membrane, clathrin-coated pit 1 LDLR
apical part of cell 3 LDLR, REN, VCAM1
clathrin-coated pit 2 LDLR, SELE
Membrane raft 3 ABCA1, ICAM1, SELE
focal adhesion 1 ICAM1
extracellular matrix 1 VWF
intracellular vesicle 1 ABCA1
collagen-containing extracellular matrix 3 APOC3, ICAM1, VWF
Late endosome 1 LDLR
receptor complex 1 LDLR
chromatin 1 PRL
cytoskeleton 1 NOS3
podosome 1 VCAM1
brush border membrane 1 ACE
blood microparticle 1 APOA2
sperm midpiece 1 ACE
Endomembrane system 1 LDLR
endosome lumen 1 PRL
sorting endosome 1 LDLR
microvillus 1 VCAM1
Cytoplasm, Stress granule 1 NOS3
cytoplasmic stress granule 1 NOS3
basal plasma membrane 1 ACE
platelet alpha granule 1 VWF
exocytic vesicle 1 IGF1
endoplasmic reticulum lumen 1 APOA2
platelet alpha granule lumen 2 IGF1, VWF
endocytic vesicle membrane 1 NOS3
endocytic vesicle 1 ABCA1
azurophil granule lumen 1 NPC2
immunological synapse 1 ICAM1
clathrin-coated endocytic vesicle membrane 1 LDLR
endolysosome membrane 1 LDLR
death-inducing signaling complex 1 CASP3
somatodendritic compartment 1 LDLR
spherical high-density lipoprotein particle 2 APOA2, APOC3
PCSK9-LDLR complex 1 LDLR
intermediate-density lipoprotein particle 1 APOC3
cortical cytoskeleton 1 SELE
Weibel-Palade body 1 VWF
alphav-beta3 integrin-IGF-1-IGF1R complex 1 IGF1
insulin-like growth factor binding protein complex 1 IGF1
insulin-like growth factor ternary complex 1 IGF1
catalytic complex 1 LPL
[Angiotensin-converting enzyme, soluble form]: Secreted 1 ACE
[Isoform Testis-specific]: Cell membrane 1 ACE
[Vascular cell adhesion protein 1]: Cell membrane 1 VCAM1
[Soluble Vascular Cell Adhesion Molecule-1]: Secreted 1 VCAM1
alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex 1 VCAM1


文献列表

  • Hui Ao, Huizhu Song, Jing Li, Xiangtao Wang. Enhanced anti-glioma activity of annonaceous acetogenins based on a novel liposomal co-delivery system with ginsenoside Rh2. Drug delivery. 2024 Dec; 31(1):2324716. doi: 10.1080/10717544.2024.2324716. [PMID: 38555735]
  • Matteo Veronese, Sebastian Kallabis, Alexander Tobias Kaczmarek, Anushka Das, Lennart Robers, Simon Schumacher, Alessia Lofrano, Susanne Brodesser, Stefan Müller, Kay Hofmann, Marcus Krüger, Elena I Rugarli. ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway. Life science alliance. 2024 Aug; 7(8):. doi: 10.26508/lsa.202402620. [PMID: 38782601]
  • Magdalena Kulma, Aleksandra Šakanović, Apolonija Bedina-Zavec, Simon Caserman, Neža Omersa, Gašper Šolinc, Sara Orehek, Iva Hafner-Bratkovič, Urška Kuhar, Brigita Slavec, Uroš Krapež, Matjaž Ocepek, Toshihide Kobayashi, Katarzyna Kwiatkowska, Roman Jerala, Marjetka Podobnik, Gregor Anderluh. Sequestration of membrane cholesterol by cholesterol-binding proteins inhibits SARS-CoV-2 entry into Vero E6 cells. Biochemical and biophysical research communications. 2024 Jul; 716(?):149954. doi: 10.1016/j.bbrc.2024.149954. [PMID: 38704887]
  • Yu Chun Teng, Marie Claire Gielen, Nina M de Gruijter, Coziana Ciurtin, Elizabeth C Rosser, Kersti Karu. Phytosterols in human serum as measured using a liquid chromatography tandem mass spectrometry. The Journal of steroid biochemistry and molecular biology. 2024 Jul; 241(?):106519. doi: 10.1016/j.jsbmb.2024.106519. [PMID: 38614432]
  • Silu Basumatary, Partha Pradip Adhikari, Ajit Kumar Das, Nanjian Raaman, Gauri Dutt Sharma, Jatin Sarmah, Anjum Dihingia, Rinku Baishya, Prasenjit Manna, Jatin Kalita. Antihyperglycemic and antihyperlipidemic effects of fruit extract of Hodgsonia heteroclita (Roxb.) Hook. f. & Thomson in diabetic mice. Journal of ethnopharmacology. 2024 Jun; 328(?):118094. doi: 10.1016/j.jep.2024.118094. [PMID: 38521433]
  • Xufeng Bai, Shuwen Wang, Limei Shu, Qingyu Cao, Huiming Hu, Yanchen Zhu, Chen Chen. Hawthorn leaf flavonoids alleviate the deterioration of atherosclerosis by inhibiting SCAP-SREBP2-LDLR pathway through sPLA2-ⅡA signaling in macrophages in mice. Journal of ethnopharmacology. 2024 Jun; 327(?):118006. doi: 10.1016/j.jep.2024.118006. [PMID: 38442806]
  • Saman Yasamineh, Fatemeh Jabbari Mehrabani, Ehsan Derafsh, Renizo Danihiel Cosimi, Amir Mohammad Karimi Forood, Siamak Soltani, Meead Hadi, Omid Gholizadeh. Potential Use of the Cholesterol Transfer Inhibitor U18666A as a Potent Research Tool for the Study of Cholesterol Mechanisms in Neurodegenerative Disorders. Molecular neurobiology. 2024 Jun; 61(6):3503-3527. doi: 10.1007/s12035-023-03798-7. [PMID: 37995080]
  • Alexa Guglielmelli, Caterina M Tone, Eleonora Ragozzino, Federica Ciuchi, Rosa Bartucci. Cholesterol drives enantiospecific effects of ibuprofen in biomimetic membranes. Biochimica et biophysica acta. Biomembranes. 2024 Jun; 1866(5):184334. doi: 10.1016/j.bbamem.2024.184334. [PMID: 38744417]
  • Yueyue Li, Yang Chen, Cheng Zhao, Yuting Yang, Mei Zhang, Hui Cheng, Qinglin Li, Meng Wang. Arenobufagin modulation of PCSK9-mediated cholesterol metabolism induces tumor-associated macrophages polarisation to inhibit hepatocellular carcinoma progression. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jun; 128(?):155532. doi: 10.1016/j.phymed.2024.155532. [PMID: 38493722]
  • Onesun Jung, Hye-Youn Jung, Le Thi Thuy, Minyoung Choi, Seongyeon Kim, Hae-Geun Jeon, Jihyun Yang, Seok-Min Kim, Tae-Don Kim, Eunjung Lee, Yoonkyung Kim, Joon Sig Choi. Modulating Lipid Nanoparticles with Histidinamide-Conjugated Cholesterol for Improved Intracellular Delivery of mRNA. Advanced healthcare materials. 2024 Jun; 13(14):e2303857. doi: 10.1002/adhm.202303857. [PMID: 38344923]
  • Ziang Li, Rani Baidoun, Angela C Brown. Toxin-triggered liposomes for the controlled release of antibiotics to treat infections associated with the gram-negative bacterium, Aggregatibacter actinomycetemcomitans. Colloids and surfaces. B, Biointerfaces. 2024 Jun; 238(?):113870. doi: 10.1016/j.colsurfb.2024.113870. [PMID: 38555763]
  • Blanca Delgado-Coello, Ismael Luna-Reyes, Kevin M Méndez-Acevedo, Jorge Bravo-Martínez, Danai Montalvan-Sorrosa, Jaime Mas-Oliva. Analysis of cholesterol-recognition motifs of the plasma membrane Ca2+-ATPase. Journal of bioenergetics and biomembranes. 2024 Jun; 56(3):205-219. doi: 10.1007/s10863-024-10010-5. [PMID: 38436904]
  • Affiong Ika Oqua, Yusman Manchanda, Emma Rose McGlone, Ben Jones, Sarah Rouse, Alejandra Tomas. Lipid regulation of the glucagon receptor family. The Journal of endocrinology. 2024 Jun; 261(3):. doi: 10.1530/joe-23-0335. [PMID: 38614123]
  • Paolo Raggi, Maria Laura Becciu, Eliano P Navarese. Remnant cholesterol as a new lipid-lowering target to reduce cardiovascular events. Current opinion in lipidology. 2024 Jun; 35(3):110-116. doi: 10.1097/mol.0000000000000921. [PMID: 38276967]
  • Mahsa Rounagh, Vali Musazadeh, Ali Hosseininejad-Mohebati, Maryam Falahatzadeh, Zeynab Kavyani, Reza Bijan Rostami, Mahdi Vajdi. Effects of Nigella sativa supplementation on lipid profiles in adults: An updated systematic review and meta-analysis of randomized controlled trials. Clinical nutrition ESPEN. 2024 Jun; 61(?):168-180. doi: 10.1016/j.clnesp.2024.03.020. [PMID: 38777430]
  • Mingxiao Luo, Peng Chen, Ye Tian, Norbu Rigzin, Jigme Sonam, Feihu Shang, Chuang Tai, Tingting Li, Haiquan Sang. Hif-1α expression targets the TMA/Fmo3/TMAO axis to participate in gallbladder cholesterol stone formation in individuals living in plateau regions. Biochimica et biophysica acta. Molecular basis of disease. 2024 Jun; 1870(5):167188. doi: 10.1016/j.bbadis.2024.167188. [PMID: 38657913]
  • Reza Talandashti, Larissa van Ek, Charlotte Gehin, Dandan Xue, Mahmoud Moqadam, Anne-Claude Gavin, Nathalie Reuter. Membrane specificity of the human cholesterol transfer protein STARD4. Journal of molecular biology. 2024 Jun; 436(11):168572. doi: 10.1016/j.jmb.2024.168572. [PMID: 38615744]
  • Wenlu Hu, Yanxia Ding, Kelei Guan, Panpan Zhang, Jingbo Su, Chunyi Zhang, Wei Li, Chaofeng Lian, Qihua Yang, Shengyun Liu, Tianfang Li. Changes in metabolic parameters and serum YKL-40 levels in Chinese rheumatoid arthritis patients during tocilizumab therapy. Clinical rheumatology. 2024 Jun; 43(6):1845-1853. doi: 10.1007/s10067-024-06982-9. [PMID: 38696116]
  • Yu Hao, Xuan'en Tian, Fengmei Yan, Xiuqin Wang, Jing Huang, Ling Li. Effect of MEHP on testosterone synthesis via Sirt1/Foxo1/Rab7 signaling pathway inhibition of lipophagy in TM3 cells. Ecotoxicology and environmental safety. 2024 Jun; 277(?):116394. doi: 10.1016/j.ecoenv.2024.116394. [PMID: 38663197]
  • Linhua Zheng, Siyuan Tian, Chunmei Yang, Bo Li, Gui Jia, Yansheng Liu, Ruiqing Sun, Xiufang Wang, Juan Deng, Miao Zhang, Lina Cui, Changcun Guo, Xinmin Zhou, Patrick S C Leung, Christopher L Bowlus, M Eric Gershwin, Yulong Shang, Ying Han. Hypercholesterolemia Is Associated With Dysregulation of Lipid Metabolism and Poor Prognosis in Primary Biliary Cholangitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2024 Jun; 22(6):1265-1274.e19. doi: 10.1016/j.cgh.2024.01.039. [PMID: 38354969]
  • Yvonne Benatzy, Megan A Palmer, Dieter Lütjohann, Rei-Ichi Ohno, Nadja Kampschulte, Nils Helge Schebb, Dominik C Fuhrmann, Ryan G Snodgrass, Bernhard Brüne. ALOX15B controls macrophage cholesterol homeostasis via lipid peroxidation, ERK1/2 and SREBP2. Redox biology. 2024 Jun; 72(?):103149. doi: 10.1016/j.redox.2024.103149. [PMID: 38581859]
  • Jin-Hua Liang, Wei-Ting Wang, Rong Wang, Rui Gao, Kai-Xin Du, Zi-Wen Duan, Xin-Yu Zhang, Yue Li, Jia-Zhu Wu, Hua Yin, Hao-Rui Shen, Li Wang, Jian-Yong Li, Jin-Ran Guo, Wei Xu. PRMT5 activates lipid metabolic reprogramming via MYC contributing to the growth and survival of mantle cell lymphoma. Cancer letters. 2024 Jun; 591(?):216877. doi: 10.1016/j.canlet.2024.216877. [PMID: 38615930]
  • Shima Akar, Somayeh Fardindoost, Mina Hoorfar. High throughput microfluidics-based synthesis of PEGylated liposomes for precise size control and efficient drug encapsulation. Colloids and surfaces. B, Biointerfaces. 2024 Jun; 238(?):113926. doi: 10.1016/j.colsurfb.2024.113926. [PMID: 38677154]
  • Carolina Gastelum Guerrero, Yuridia Lizet Cháidez Fernández, Dalia Magaña Ordorica, Heidi Berger, Marilyn Vazquez Landrove, Alma Guadrón Llanos, Carla Angulo Rojo, Javier Magaña Gómez. A systematic review and meta-analysis of serum lipid concentrations in people with Down syndrome. Journal of intellectual disability research : JIDR. 2024 Jun; 68(6):553-563. doi: 10.1111/jir.13128. [PMID: 38404114]
  • Sylvia Riedel, Stefan Abel, Hester-Mari Burger, Sonja Swanevelder, Wentzel C A Gelderblom. Fumonisin B1 protects against long-chained polyunsaturated fatty acid-induced cell death in HepG2 cells - implications for cancer promotion. Biochimica et biophysica acta. Biomembranes. 2024 Jun; 1866(5):184310. doi: 10.1016/j.bbamem.2024.184310. [PMID: 38479610]
  • Hong Wang, Lijia Chen, Ruiyu Zhang, Guanying Zhang, Jingwen Liu, Fujiang Guo. Curcuma wenyujin rhizomes extract ameliorates lipid accumulation. Fitoterapia. 2024 Jun; 175(?):105957. doi: 10.1016/j.fitote.2024.105957. [PMID: 38604260]
  • Tugce Demirel-Yalciner, Bengu Cetinkaya, Erdi Sozen, Nesrin Kartal Ozer. Impact of Seipin in cholesterol mediated lipid droplet maturation; status of endoplasmic reticulum stress and lipophagy. Mechanisms of ageing and development. 2024 Jun; 219(?):111933. doi: 10.1016/j.mad.2024.111933. [PMID: 38588730]
  • Andreea Nădăban, Gerrit S Gooris, Charlotte M Beddoes, Robert M Dalgliesh, Marc Malfois, Bruno Demé, Joke A Bouwstra. The molecular arrangement of ceramides in the unit cell of the long periodicity phase of stratum corneum models shows a high adaptability to different ceramide head group structures. Biochimica et biophysica acta. Biomembranes. 2024 Jun; 1866(5):184324. doi: 10.1016/j.bbamem.2024.184324. [PMID: 38688405]
  • Shuyun Lin, Lianjie Hou, Yu Wang, Huiling Lin, Jiefeng Deng, Shuang Li, Haijiao Long, Guojun Zhao. Antagonism of let-7c reduces atherosclerosis and macrophage lipid accumulation by promoting PGC-1α/LXRα/ABCA1/G1 pathway. Gene. 2024 May; 909(?):148302. doi: 10.1016/j.gene.2024.148302. [PMID: 38401833]
  • Teresa Padro, Victoria Santisteban, Pol Huedo, Montserrat Puntes, Meritxell Aguiló, Jordi Espadaler-Mazo, Lina Badimon. Lactiplantibacillus plantarum strains KABP011, KABP012, and KABP013 modulate bile acids and cholesterol metabolism in humans. Cardiovascular research. 2024 May; 120(7):708-722. doi: 10.1093/cvr/cvae061. [PMID: 38525555]
  • Kevin Jahnke, Marko Pavlovic, Wentao Xu, Anqi Chen, Tuomas P J Knowles, Laura R Arriaga, David A Weitz. Polysaccharide functionalization reduces lipid vesicle stiffness. Proceedings of the National Academy of Sciences of the United States of America. 2024 May; 121(22):e2317227121. doi: 10.1073/pnas.2317227121. [PMID: 38771870]
  • Haiying Lv, Yu Cao, Jin Zhu, Qing Liang. Molecular Insights into the Effect of Cholesterol on the Binding of Bicarbonate Ions in Band 3 Protein. Langmuir : the ACS journal of surfaces and colloids. 2024 May; 40(21):10908-10915. doi: 10.1021/acs.langmuir.4c00216. [PMID: 38739034]
  • Farzaneh Jalalypour, Rebecca J Howard, Erik Lindahl. Allosteric Cholesterol Site in Glycine Receptors Characterized through Molecular Simulations. The journal of physical chemistry. B. 2024 May; 128(20):4996-5007. doi: 10.1021/acs.jpcb.4c01703. [PMID: 38747451]
  • Swaratmika Pandia, Amita Mahapatra, Hirak Chakraborty. A Coronin 1-Derived Peptide Inhibits Membrane Fusion by Modulating Membrane Organization and Dynamics. The journal of physical chemistry. B. 2024 May; 128(20):4986-4995. doi: 10.1021/acs.jpcb.4c00295. [PMID: 38739415]
  • Xixi Zeng, Ling Chen, Bo Zheng. Extrusion and chlorogenic acid treatment increase the ordered structure and resistant starch levels in rice starch with amelioration of gut lipid metabolism in obese rats. Food & function. 2024 May; 15(10):5224-5237. doi: 10.1039/d3fo05416k. [PMID: 38623646]
  • Yanxue Wang, Liang Li, Lingling Chen, Jinlei Xia, Tongli Wang, Lei Han, Liang Cao, Zhenzhong Wang, Wei Xiao, Shan Jiang. The Influence of Emodin Succinyl Ethyl Ester on Non-alcoholic Steatohepatitis Induced by a Diet High in Fructose, Cholesterol, and Fat in Mice. Biological & pharmaceutical bulletin. 2024 May; 47(5):978-987. doi: 10.1248/bpb.b23-00903. [PMID: 38631865]
  • V Kokila, S Karthick Raja Namasivayam, K Amutha, R Ramesh Kumar, R S Arvind Bharani, P Surya. Hypocholesterolemic potential of Bacillus amyloliquefaciens KAVK1 modulates lipid accumulation on 3T3-L1 adipose cells and high fat diet-induced obese rat model. World journal of microbiology & biotechnology. 2024 May; 40(7):206. doi: 10.1007/s11274-024-04016-9. [PMID: 38755297]
  • Romain Riscal, Sarah M Gardner, Nathan J Coffey, Madeleine Carens, Clementina Mesaros, Jimmy P Xu, Yizheng Xue, Leah Davis, Sara Demczyszyn, Austin Vogt, Adam Olia, Jennifer M Finan, Jason Godfrey, David C Schultz, Ian A Blair, Brian Keith, Ronen Marmorstein, Nicolas Skuli, M Celeste Simon. Bile Acid Metabolism Mediates Cholesterol Homeostasis and Promotes Tumorigenesis in Clear Cell Renal Cell Carcinoma. Cancer research. 2024 May; 84(10):1570-1582. doi: 10.1158/0008-5472.can-23-0821. [PMID: 38417134]
  • Xiayan Yu, Wenjing Qiang, Kexin Gong, Yidan Cao, Shuangqin Yan, Guopeng Gao, Fangbiao Tao, Beibei Zhu. No role of the third-trimester inflammatory factors in the association of gestational diabetes mellitus with postpartum cardiometabolic indicators. BMC pregnancy and childbirth. 2024 May; 24(1):361. doi: 10.1186/s12884-024-06563-3. [PMID: 38750471]
  • Hanna Orlikowska-Rzeznik, Jan Versluis, Huib J Bakker, Lukasz Piatkowski. Cholesterol Changes Interfacial Water Alignment in Model Cell Membranes. Journal of the American Chemical Society. 2024 May; 146(19):13151-13162. doi: 10.1021/jacs.4c00474. [PMID: 38687869]
  • Kenneth K Y Ting, Pei Yu, Riley Dow, Hisham Ibrahim, Saraf Karim, Chanele K Polenz, Daniel A Winer, Minna Woo, Jenny Jongstra-Bilen, Myron I Cybulsky. Cholesterol accumulation impairs HIF-1α-dependent immunometabolic reprogramming of LPS-stimulated macrophages by upregulating the NRF2 pathway. Scientific reports. 2024 05; 14(1):11162. doi: 10.1038/s41598-024-61493-6. [PMID: 38750095]
  • Mohamed J Saadh, Behina Bazghandi, Hamid Jamialahmdi, Fatemeh Rahimzadeh-Bajgiran, Fatemeh Forouzanfar, Seyed-Alireza Esmaeili, Ehsan Saburi. Therapeutic potential of lipid-lowering probiotics on the atherosclerosis development. European journal of pharmacology. 2024 May; 971(?):176527. doi: 10.1016/j.ejphar.2024.176527. [PMID: 38554932]
  • Lei Zhu, Yilin Shi, Zhelong Feng, Dingyi Yuan, Shiduo Guo, Yuxia Wang, Haowen Shen, Yan Li, Fang Yan, Yajing Wang. Fatostatin promotes anti-tumor immunity by reducing SREBP2 mediated cholesterol metabolism in tumor-infiltrating T lymphocytes. European journal of pharmacology. 2024 May; 971(?):176519. doi: 10.1016/j.ejphar.2024.176519. [PMID: 38522641]
  • Mengyun Dong, Tianliang Zhang, Xueli Liang, Xinyi Cheng, Fuyan Shi, Hang Yuan, Fengxiang Zhang, Qiqi Jiang, Xia Wang. Sesamin alleviates lipid accumulation induced by oleic acid via PINK1/Parkin-mediated mitophagy in HepG2 cells. Biochemical and biophysical research communications. 2024 May; 708(?):149815. doi: 10.1016/j.bbrc.2024.149815. [PMID: 38531220]
  • Shujiang Zhuo, Sufei Song, Chaoyi Wang, Zhe Wang, Ming Zhang, Daobin Lin, Kaili Chen. Inflammatory corpuscle AIM2 facilitates macrophage foam cell formation by inhibiting cholesterol efflux protein ABCA1. Scientific reports. 2024 05; 14(1):10782. doi: 10.1038/s41598-024-61495-4. [PMID: 38734775]
  • Ke Xu, Shuang Zhao, Yi Ren, Qi Zhong, Jinzhou Feng, Dianji Tu, Wentao Wu, Jiaolin Wang, Jianjun Chen, Peng Xie. Elevated SCN11A concentrations associated with lower serum lipid levels in patients with major depressive disorder. Translational psychiatry. 2024 May; 14(1):202. doi: 10.1038/s41398-024-02916-w. [PMID: 38734669]
  • Hui Guo, Bing-di Cui, Man Gong, Qing-Xia Li, Ling-Xia Zhang, Jia-Li Chen, Jun Chi, Li-Li Zhu, Er-Ping Xu, Zhi-Min Wang, Li-Ping Dai. An ethanolic extract of Arctium lappa L. leaves ameliorates experimental atherosclerosis by modulating lipid metabolism and inflammatory responses through PI3K/Akt and NF-κB singnaling pathways. Journal of ethnopharmacology. 2024 May; 325(?):117768. doi: 10.1016/j.jep.2024.117768. [PMID: 38253275]
  • Pui Ying Yew, Matt Loth, Terrence J Adam, Julian Wolfson, Yue Liang, Peter J Tonellato, Chih-Lin Chi. Potential impact of blood cholesterol guidelines on statin treatment in the U.S. population using interrupted time series analysis. BMC cardiovascular disorders. 2024 May; 24(1):245. doi: 10.1186/s12872-024-03921-z. [PMID: 38730371]
  • Wei Chen, Jing Zhang, Fenxiang Li, Zongshun Chen, Junjie Li, Da-Lin Lu. Association between pathologic complete response and biochemical indicators after neoadjuvant therapy for HER2-positive breast cancer. World journal of surgical oncology. 2024 May; 22(1):126. doi: 10.1186/s12957-024-03366-w. [PMID: 38725003]
  • Qingting Bu, Lingyan Fang, Bo Huang, Huijun Cai, Zhenyu Pan. The association between alcohol consumption and blood lipids in Chinese children and adolescent: findings from the China Health and Nutrition Survey. BMC pediatrics. 2024 May; 24(1):320. doi: 10.1186/s12887-024-04807-x. [PMID: 38724982]
  • Zhifan Li, Yanan Gao, Qianhong Lu, Zheng Yin, Shuang Zhang, Wenjia Zhang, Yonggang Sui, Yanlu Xu, Jianjun Li, Kefei Dou, Jie Qian, Hong Qiu, Naqiong Wu. The effect of lipid-lowering therapy on lipid-related residual risk factors: a prospective study. Lipids in health and disease. 2024 May; 23(1):134. doi: 10.1186/s12944-024-02078-0. [PMID: 38715079]
  • Nigel Unwin. Influence of lipid bilayer on the structure of the muscle-type nicotinic acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. 2024 May; 121(19):e2319913121. doi: 10.1073/pnas.2319913121. [PMID: 38683987]
  • Jaime Rosales-Rimache, Jeisson Apaza-Condori, Jhonatan Rabanal-Sanchez, Li Jari, Fernando Soncco-Llulluy. Comparison of the Friedewald and Vujovic methods with the calculated LDL concentration in a biochemical auto-analyzer. Medwave. 2024 May; 24(4):e2775. doi: 10.5867/medwave.2024.04.2775. [PMID: 38710047]
  • Mikhail Matveyenka, Kiryl Zhaliazka, Dmitry Kurouski. Macrophages and Natural Killers Degrade α-Synuclein Aggregates. Molecular pharmaceutics. 2024 May; 21(5):2565-2576. doi: 10.1021/acs.molpharmaceut.4c00160. [PMID: 38635186]
  • Zhaoxian Zhang, Yaoyi Jia, Chenghui Zhang, Zikang Zhang, Fangsha Jin, Dandan Pan, Daxiang Li, Xiangwei Wu. Efficacy of epigallocatechin gallate (EGCG) and its underlying mechanism in preventing bisphenol-A-induced metabolic disorders in mice. Journal of hazardous materials. 2024 May; 469(?):134098. doi: 10.1016/j.jhazmat.2024.134098. [PMID: 38522198]
  • Yuanqing Gu, Björn M Reinhard. Membrane fluidity properties of lipid-coated polylactic acid nanoparticles. Nanoscale. 2024 May; 16(17):8533-8545. doi: 10.1039/d3nr06464f. [PMID: 38595322]
  • Shuo Qian, Gergely Nagy, Piotr Zolnierczuk, Eugene Mamontov, Robert Standaert. Nonstereotypical Distribution and Effect of Ergosterol in Lipid Membranes. The journal of physical chemistry letters. 2024 May; 15(17):4745-4752. doi: 10.1021/acs.jpclett.4c00385. [PMID: 38661394]
  • Ketan Kumar, Rakesh Lodha, Kana Ram Jat, Vandana Jain, Sushil K Kabra. Prevalence of Metabolic Abnormalities and their Association with Asthma Symptom Control in Children. Indian journal of pediatrics. 2024 May; 91(5):434-440. doi: 10.1007/s12098-023-04716-4. [PMID: 37470958]
  • Athina Maniscalchi, Oriana N Benzi Juncos, Melisa A Conde, Melania I Funk, María E Fermento, María M Facchinetti, Alejandro C Curino, Romina M Uranga, Natalia P Alza, Gabriela A Salvador. New insights on neurodegeneration triggered by iron accumulation: Intersections with neutral lipid metabolism, ferroptosis, and motor impairment. Redox biology. 2024 May; 71(?):103074. doi: 10.1016/j.redox.2024.103074. [PMID: 38367511]
  • Chanho Lee, Se Hyun Kwak, Jisu Han, Ju Hye Shin, Byunghun Yoo, Yu Seol Lee, Jeong Su Park, Beom Jin Lim, Jin Gu Lee, Young Sam Kim, Song Yee Kim, Soo Han Bae. Repositioning of ezetimibe for the treatment of idiopathic pulmonary fibrosis. The European respiratory journal. 2024 May; 63(5):. doi: 10.1183/13993003.00580-2023. [PMID: 38359963]
  • Angela K Jarman, Michelle E Shaw, Sonia Y Liu, Catherine E Grueber. An insight into vitamin E and lipid nutrition of the plains-wanderer Pedionomus torquatus. Zoo biology. 2024 May; 43(3):213-223. doi: 10.1002/zoo.21815. [PMID: 38294092]
  • Peng Wang, Xue Lian Liu, Zong Zhe Jiang, Yang Long, Chen Lin Gao, Wei Huang, Xiao Zhen Tan, Xiu Mei Ma, Yong Xu. Effect of proanthocyanidins on blood lipids: A systematic review and meta-analysis. Phytotherapy research : PTR. 2024 May; 38(5):2154-2164. doi: 10.1002/ptr.8162. [PMID: 38391003]
  • Jing Zhang, Qing-Hua Wang, Ben-Ben Miao, Ren-Xie Wu, Qian-Qian Li, Bao-Gui Tang, Zhen-Bang Liang, Su-Fang Niu. Liver transcriptome analysis reveal the metabolic and apoptotic responses of Trachinotus ovatus under acute cold stress. Fish & shellfish immunology. 2024 May; 148(?):109476. doi: 10.1016/j.fsi.2024.109476. [PMID: 38447780]
  • Suresh Govatati, Raj Kumar, Monoranjan Boro, James G Traylor, A Wayne Orr, Aldons J Lusis, Gadiparthi N Rao. TRIM13 reduces cholesterol efflux and increases oxidized LDL uptake leading to foam cell formation and atherosclerosis. The Journal of biological chemistry. 2024 May; 300(5):107224. doi: 10.1016/j.jbc.2024.107224. [PMID: 38537695]
  • Kun Li, Wen-Wen Cao, Shao-Hua Chen, Bin-Fei Zhang, Yu-Min Zhang. Association between total cholesterol and all-cause mortality in geriatric patients with hip fractures: A prospective cohort study with 339 patients. Advances in clinical and experimental medicine : official organ Wroclaw Medical University. 2024 May; 33(5):463-471. doi: 10.17219/acem/169795. [PMID: 37593772]
  • Brittany M White-Mathieu, Jeremy M Baskin. Super-Resolution Imaging of Clickable Lipids With Lipid Expansion Microscopy (LExM). Current protocols. 2024 May; 4(5):e1051. doi: 10.1002/cpz1.1051. [PMID: 38779885]
  • Binqi Li, Xin Zhou, Yang Liu, Yue Zhang, Yiming Mu. Remnant Cholesterol is More Strongly Associated with Arterial Stiffness than Traditional Lipids and Lipid Ratios in the General Chinese Population. Journal of atherosclerosis and thrombosis. 2024 May; 31(5):587-602. doi: 10.5551/jat.64146. [PMID: 38171806]
  • Madiha Sajid, Sadaf Ahmed Asim, Tayyaba Iqbal, Sadia Bhatti, Ayesha Zahir, Sania Imtiaz. Isotretinoin's Effect on Fasting Lipid Profile in Acne Patients. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. 2024 May; 34(5):518-521. doi: 10.29271/jcpsp.2024.05.518. [PMID: 38720209]
  • Yubexi Correa, Mathilde Ravel, Marie Imbert, Sarah Waldie, Luke Clifton, Ann Terry, Felix Roosen-Runge, Jens O Lagerstedt, Michael Moir, Tamim Darwish, Marité Cárdenas, Rita Del Giudice. Lipid exchange of apolipoprotein A-I amyloidogenic variants in reconstituted high-density lipoprotein with artificial membranes. Protein science : a publication of the Protein Society. 2024 May; 33(5):e4987. doi: 10.1002/pro.4987. [PMID: 38607188]
  • Yuna Tanaka, Chihiro Inaba, Toko Sawa, Katsunori Endo, Takeru Saiki, Hazuki Haga, Fumie Niitsuma, Takeshi Kawahara, Jun Watanabe, Sachi Tanaka. Heat-killed Lactiplantibacillus plantarum Shinshu N-07 exerts antiobesity effects in western diet-induced obese mice. Journal of applied microbiology. 2024 May; 135(5):. doi: 10.1093/jambio/lxae119. [PMID: 38740521]
  • Behnam Ahmadipour, Majid Kalantar, Samira Abaszadeh, Hossein Hassanpour. Antioxidant and antihyperlipidemic effects of hawthorn extract (Crataegus oxyacantha) in broiler chickens. Veterinary medicine and science. 2024 05; 10(3):e1414. doi: 10.1002/vms3.1414. [PMID: 38504617]
  • Lin Tang, Rui Zhang, Yusi Wang, Mohan Liu, Die Hu, Yefeng Wang, Li Yang. A blood-brain barrier- and blood-brain tumor barrier-penetrating siRNA delivery system targeting gliomas for brain tumor immunotherapy. Journal of controlled release : official journal of the Controlled Release Society. 2024 May; 369(?):642-657. doi: 10.1016/j.jconrel.2024.04.006. [PMID: 38575072]
  • Antonina I Frolova, Kevin K Prifti, Nandini Raghuraman, Ebony B Carter, Sarah K England, Molly J Stout. Association between Maternal Serum Lipids and Intrapartum Oxytocin Requirements during Labor Induction and Augmentation. American journal of perinatology. 2024 May; 41(S 01):e1015-e1022. doi: 10.1055/a-1979-8577. [PMID: 36384236]
  • Linqiang Zhang, Yongqiong Shi, Bin Liang, Xi Li. An overview of the cholesterol metabolism and its proinflammatory role in the development of MASLD. Hepatology communications. 2024 May; 8(5):. doi: 10.1097/hc9.0000000000000434. [PMID: 38696365]
  • Ana Fernanda Castillo, Cecilia Poderoso, Paula Mariana Maloberti, Fabiana Cornejo Maciel, María Mercedes Mori Sequeiros Garcia, Ulises Daniel Orlando, Pablo Mele, Yanina Benzo, Melina Andrea Dattilo, Jesica Prada, Luciano Quevedo, Matías Belluno, Cristina Paz, Ernesto Jorge Podesta. Specific cellular microenvironments for spatiotemporal regulation of StAR and steroid synthesis. The Journal of endocrinology. 2024 May; 261(2):. doi: 10.1530/joe-23-0391. [PMID: 38470178]
  • Anusha B Gopalan, Lisa van Uden, Richard R Sprenger, Nadine Fernandez-Novel Marx, Helle Bogetofte, Pierre A Neveu, Morten Meyer, Kyung-Min Noh, Alba Diz-Muñoz, Christer S Ejsing. Lipotype acquisition during neural development is not recapitulated in stem cell-derived neurons. Life science alliance. 2024 May; 7(5):. doi: 10.26508/lsa.202402622. [PMID: 38418090]
  • Xiaofeng Zhang, Caixia Wang, Ruixue Min, Qilun Zhou, Yue Qi, Jianming Fan. Cardamom consumption may improve cardiovascular metabolic biomarkers in adults: A systematic review and meta-analysis of randomized controlled trials. Nutrition research (New York, N.Y.). 2024 May; 125(?):101-112. doi: 10.1016/j.nutres.2024.03.002. [PMID: 38593657]
  • Feng Geng, Deliang Guo. SREBF1/SREBP-1 concurrently regulates lipid synthesis and lipophagy to maintain lipid homeostasis and tumor growth. Autophagy. 2024 May; 20(5):1183-1185. doi: 10.1080/15548627.2023.2275501. [PMID: 37927089]
  • Hudson W Coates, Tina B Nguyen, Ximing Du, Ellen M Olzomer, Rhonda Farrell, Frances L Byrne, Hongyuan Yang, Andrew J Brown. The constitutively active form of a key cholesterol synthesis enzyme is lipid droplet-localized and upregulated in endometrial cancer tissues. The Journal of biological chemistry. 2024 May; 300(5):107232. doi: 10.1016/j.jbc.2024.107232. [PMID: 38537696]
  • Benjamin N Wadström, Kasper M Pedersen, Anders B Wulff, Børge G Nordestgaard. Remnant Cholesterol, Not LDL Cholesterol, Explains Peripheral Artery Disease Risk Conferred by apoB: A Cohort Study. Arteriosclerosis, thrombosis, and vascular biology. 2024 May; 44(5):1144-1155. doi: 10.1161/atvbaha.123.320175. [PMID: 38511326]
  • Swen Bremer, Eva Weitkemper, Hanns Häberlein, Sebastian Franken. St. John's wort extract Ze 117 alters the membrane fluidity of C6 glioma cells by influencing cellular cholesterol metabolism. Scientific reports. 2024 04; 14(1):9878. doi: 10.1038/s41598-024-60562-0. [PMID: 38684848]
  • Lih-Lih Ong, Hau-Ming Jan, Hong-Hanh Thi Le, Tsai-Chen Yang, Chou-Yu Kuo, Ai-Feng Feng, Kwok-Kong Tony Mong, Chun-Hung Lin. Membrane lipid remodeling eradicates Helicobacter pylori by manipulating the cholesteryl 6'-acylglucoside biosynthesis. Journal of biomedical science. 2024 Apr; 31(1):44. doi: 10.1186/s12929-024-01031-8. [PMID: 38685037]
  • Yan Liu, Xiaohan Tang, Hailong Yuan, Rong Gao. Naringin Inhibits Macrophage Foam Cell Formation by Regulating Lipid Homeostasis and Metabolic Phenotype. Nutrients. 2024 Apr; 16(9):. doi: 10.3390/nu16091321. [PMID: 38732567]
  • Nobunao Wakabayashi, Yoko Yagishita, Tanvi Joshi, Thomas W Kensler. Dual Deletion of Keap1 and Rbpjκ Genes in Liver Leads to Hepatomegaly and Hypercholesterolemia. International journal of molecular sciences. 2024 Apr; 25(9):. doi: 10.3390/ijms25094712. [PMID: 38731931]
  • Eman Jaradat, Adam Meziane, Dimitrios A Lamprou. Conventional vs PEGylated loaded liposomal formulations by microfluidics for delivering hydrophilic chemotherapy. International journal of pharmaceutics. 2024 Apr; 655(?):124077. doi: 10.1016/j.ijpharm.2024.124077. [PMID: 38569975]
  • Hanna Orlikowska-Rzeznik, Emilia Krok, Maria Domanska, Piotr Setny, Anna Lągowska, Madhurima Chattopadhyay, Lukasz Piatkowski. Dehydration of Lipid Membranes Drives Redistribution of Cholesterol Between Lateral Domains. The journal of physical chemistry letters. 2024 Apr; 15(16):4515-4522. doi: 10.1021/acs.jpclett.4c00332. [PMID: 38634827]
  • Zhaoli Jiang, Shasha Liu, Shideng Yuan, Heng Zhang, Shiling Yuan. Models of the Three-Component Bilayer of Stratum Corneum: A Molecular Simulation Study. The journal of physical chemistry. B. 2024 Apr; 128(16):3833-3843. doi: 10.1021/acs.jpcb.3c08461. [PMID: 38603528]
  • Ádám Horváth, Anita Steib, Andrea Nehr-Majoros, Boglárka Kántás, Ágnes Király, Márk Racskó, Balázs István Tóth, Eszter Szánti-Pintér, Eva Kudová, Rita Skoda-Földes, Zsuzsanna Helyes, Éva Szőke. Anti-Nociceptive Effects of Sphingomyelinase and Methyl-Beta-Cyclodextrin in the Icilin-Induced Mouse Pain Model. International journal of molecular sciences. 2024 Apr; 25(9):. doi: 10.3390/ijms25094637. [PMID: 38731855]
  • Yue Zhang, Miao Zeng, Xiaolu Zhang, Qun Yu, Luming Wang, Wenyun Zeng, Yijing Wang, Yanrong Suo, Xijuan Jiang. Tiaogan daozhuo formula attenuates atherosclerosis via activating AMPK -PPARγ-LXRα pathway. Journal of ethnopharmacology. 2024 Apr; 324(?):117814. doi: 10.1016/j.jep.2024.117814. [PMID: 38286155]
  • Xiaoqi Shao, Wenru Zeng, Qing Wang, Suping Liu, Qiaoling Guo, Duosheng Luo, Qingmao Luo, Dongwei Wang, Lexun Wang, Yue Zhang, Hongtao Diao, Shenghua Piao, Meiling Yan, Jiao Guo. Fufang Zhenzhu Tiaozhi (FTZ) suppression of macrophage pyroptosis: Key to stabilizing rupture-prone plaques. Journal of ethnopharmacology. 2024 Apr; 324(?):117705. doi: 10.1016/j.jep.2024.117705. [PMID: 38219878]
  • Styliani Panagiotou, Kia Wee Tan, Phuoc My Nguyen, Andreas Müller, Affiong Ika Oqua, Alejandra Tomas, Anna Wendt, Lena Eliasson, Anders Tengholm, Michele Solimena, Olof Idevall-Hagren. OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion. Cell reports. 2024 Apr; 43(4):113992. doi: 10.1016/j.celrep.2024.113992. [PMID: 38536815]
  • Ximing Yu, Shilu Dou, Liaodong Lu, Meng Wang, Zhongfeng Li, Dongwei Wang. Relationship between lipid metabolism, coagulation and other blood indices and etiology and staging of non-traumatic femoral head necrosis: a multivariate logistic regression-based analysis. Journal of orthopaedic surgery and research. 2024 Apr; 19(1):251. doi: 10.1186/s13018-024-04715-x. [PMID: 38643101]
  • Clifford Lingwood. Is cholesterol both the lock and key to abnormal transmembrane signals in Autism Spectrum Disorder?. Lipids in health and disease. 2024 Apr; 23(1):114. doi: 10.1186/s12944-024-02075-3. [PMID: 38643132]
  • Rebeca André, Rita Pacheco, Hugo M Santos, Maria Luísa Serralheiro. Exploring the Hypocholesterolemic Potential of a Fucus vesiculosus Extract: Omic Insights into Molecular Mechanisms at the Intestinal Level. Marine drugs. 2024 Apr; 22(4):. doi: 10.3390/md22040187. [PMID: 38667804]
  • Anna S Kashnik, Denis S Baranov, Sergei A Dzuba. Spatial Arrangement of the Drug Ibuprofen in a Model Membrane in the Presence of Lipid Rafts. The journal of physical chemistry. B. 2024 Apr; 128(15):3652-3661. doi: 10.1021/acs.jpcb.4c01507. [PMID: 38576273]
  • Sasmita Pradhan, Lipika Mirdha, Tanusree Sengupta, Hirak Chakraborty. Phosphatidylglycerol Acts as a Switch for Cholesterol-Dependent Membrane Binding of ApoE Signal Peptide. Langmuir : the ACS journal of surfaces and colloids. 2024 Apr; 40(15):8126-8132. doi: 10.1021/acs.langmuir.4c00178. [PMID: 38568020]
  • Jingrong Yang, Yaxin Li, Jialei Huang, Jiabin Lai, Xiangrui Chen, Wenxuan Xia, Yu Wang. Effect of oesophagectomy on lipid profiles in patients with oesophageal cancer combined with hyperlipidaemia: a retrospective study. Lipids in health and disease. 2024 Apr; 23(1):108. doi: 10.1186/s12944-024-02091-3. [PMID: 38622571]
  • Alemayehu Abera, Abebaw Worede, Agete Tadewos Hirigo, Rahel Alemayehu, Sintayehu Ambachew. Dyslipidemia and associated factors among adult cardiac patients: a hospital-based comparative cross-sectional study. European journal of medical research. 2024 Apr; 29(1):237. doi: 10.1186/s40001-024-01802-x. [PMID: 38622622]
  • Min Zeng, Yali Yang, Ziyan Wang, Xiuyang Zhao, Dianshu Zhu, Mengdi Wang, Yue Chen, Xin Wei. CTRP9 prevents atherosclerosis progression through changing autophagic status of macrophages by activating USP22 mediated-de-ubiquitination on Sirt1 in vitro. Molecular and cellular endocrinology. 2024 Apr; 584(?):112161. doi: 10.1016/j.mce.2024.112161. [PMID: 38280475]