4-Hydroxybenzaldehyde

4-hydroxybenzaldehyde

C7H6O2 (122.0368)


4-Hydroxybenzaldehyde, also known as 4-formylphenol or 4-hydroxybenzenecarbonal, belongs to the class of organic compounds known as hydroxybenzaldehydes. These are organic aromatic compounds containing a benzene ring carrying an aldehyde group and a hydroxyl group. A hydroxybenzaldehyde that is benzaldehyde substituted with a hydroxy group at position C-4. 4-Hydroxybenzaldehyde exists in all living organisms, ranging from bacteria to humans. 4-Hydroxybenzaldehyde is a sweet, almond, and balsam tasting compound. 4-Hydroxybenzaldehyde is found, on average, in the highest concentration within vinegars and oats. 4-Hydroxybenzaldehyde has also been detected, but not quantified, in several different foods, such as cardoons, colorado pinyons, oyster mushrooms, common chokecherries, and potato. This could make 4-hydroxybenzaldehyde a potential biomarker for the consumption of these foods. 4-hydroxybenzaldehyde is a hydroxybenzaldehyde that is benzaldehyde substituted with a hydroxy group at position C-4. It has a role as a plant metabolite, a mouse metabolite and an EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor. 4-Hydroxybenzaldehyde is a natural product found in Ficus septica, Visnea mocanera, and other organisms with data available. Occurs naturally combined in many glycosides. Constituent of vanillin. Isol. in free state from opium poppy (Papaver somniferum) A hydroxybenzaldehyde that is benzaldehyde substituted with a hydroxy group at position C-4. 4-Hydroxybenzaldehyde. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=123-08-0 (retrieved 2024-07-02) (CAS RN: 123-08-0). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.

   

4-Hydroxybenzyl alcohol

4-(Hydroxymethyl)phenol;p-Hydroxybenzyl alcohol;p-Methylolphenol

C7H8O2 (124.0524)


4-hydroxybenzyl alcohol is the cleavage product produced during the biosynthesis of the thiazole moiety of thiamine from tyrosine as part of the thiamine biosynthesis pathway. It is a derivative of benzyl alcohol which is used as a local anesthetic and to reduce pain associated with Lidocaine injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutical aid, and in perfumery and flavoring. Benzyl Alcohol is an aromatic alcohol used in a wide variety of cosmetic formulations as a fragrance component, preservative, solvent, and viscosity-decreasing agent. Benzyl Alcohol is metabolized to Benzoic Acid, which reacts with glycine and excreted as hippuric acid in the human body. Acceptable daily intakes were established by the World Health Organization at 5 mg/kg for Benzyl Alcohol. No adverse effects of benzyl alcohol have been seen in chronic exposure animal studies using rats and mice. Effects of Benzyl Alcohol in chronic exposure animal studies are limited to reduced feed intake and reduced growth. Some differences have been noted in one reproductive toxicity study using mice, but these were limited to lower maternal body weights and decreased mean litter weights. Another study also noted that fetal weight was decreased compared to controls, but a third study showed no differences between control and benzyl alcohol-treated groups. Benzyl Alcohol has been associated with an increased number of resorptions and malformations in hamsters, but there have been no reproductive or developmental toxicity findings in studies using mice and rats. Genotoxicity tests for benzyl alcohol are mostly negative, but there were some assays that were positive. Carcinogenicity studies, however, were negative. Clinical data indicates that benzyl alcohol can produce nonimmunologic contact urticaria and nonimmunologic immediate contact reactions, characterized by the appearance of wheals, erythema, and pruritis. 5\\\\% benzyl alcohol can elicit a reaction. Benzyl Alcohol is not a sensitizer at 10\\\\%. Benzyl Alcohol could be used safely at concentrations up to 5\\\\%, but that manufacturers should consider the nonimmunologic phenomena when using benzyl alcohol in cosmetic formulations designed for infants and children. Additionally, Benzyl Alcohol is considered safe up to 10\\\\% for use in hair dyes. The limited body exposure, the duration of use, and the frequency of use are considered in concluding that the nonimmunologic reactions would not be a concern. Because of the wide variety of product types in which benzyl alcohol may be used, it is likely that inhalation may be a route of exposure. The available safety tests are not considered sufficient to support the safety of benzyl alcohol in formulations where inhalation is a route of exposure. Inhalation toxicity data are needed to complete the safety assessment of benzyl alcohol where inhalation can occur. (PMID: 11766131). P-hydroxybenzyl alcohol is a member of the class of benzyl alcohols that is benzyl alcohol substituted by a hydroxy group at position 4. It has been isolated from Arcangelisia gusanlung. It has a role as a plant metabolite. It is a member of phenols and a member of benzyl alcohols. 4-Hydroxybenzyl alcohol is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). 4-Hydroxybenzyl alcohol is a natural product found in Populus laurifolia, Mesua, and other organisms with data available. Constituent of muskmelon (Cucurbita moschata) 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth[1][2][3][4]. 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth[1][2][3][4].

   

Indole-3-carboxaldehyde

1H-indole-3-carbaldehyde

C9H7NO (145.0528)


Indole-3-carboxaldehyde (IAld or I3A), also known as 3-formylindole or 3-indolealdehyde, belongs to the class of organic compounds known as indoles. Indoles are compounds containing an indole moiety, which consists of a pyrrole ring fused to benzene to form 2,3-benzopyrrole. In humans, I3A is a biologically active metabolite which acts as a receptor agonist at the aryl hydrocarbon receptor in intestinal immune cells. It stimulates the production of interleukin-22 which facilitates mucosal reactivity (PMID:27102537). I3A is a microbially derived tryptophan metabolite produced by Clostridium and Lactobacillus (PMID:30120222, 27102537). I3A has also been found in the urine of patients with untreated phenylketonuria (PMID:5073866). I3A has been detected, but not quantified, in several different foods, such as beans, Brussels sprouts, cucumbers, cereals and cereal products, and white cabbages. This could make I3A a potential biomarker for the consumption of these foods. Indole-3-carbaldehyde is a heteroarenecarbaldehyde that is indole in which the hydrogen at position 3 has been replaced by a formyl group. It has a role as a plant metabolite, a human xenobiotic metabolite, a bacterial metabolite and a marine metabolite. It is a heteroarenecarbaldehyde, an indole alkaloid and a member of indoles. Indole-3-carboxaldehyde is a natural product found in Euphorbia hirsuta, Derris ovalifolia, and other organisms with data available. A heteroarenecarbaldehyde that is indole in which the hydrogen at position 3 has been replaced by a formyl group. Found in barley and tomato seedlings and cotton Indole-3-carboxaldehyde. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=487-89-8 (retrieved 2024-07-02) (CAS RN: 487-89-8). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1]. Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1].

   

Choline

(2-hydroxyethyl)trimethylazanium

[C5H14NO]+ (104.1075)


Choline is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. Choline is now considered to be an essential vitamin. While humans can synthesize small amounts (by converting phosphatidylethanolamine to phosphatidylcholine), it must be consumed in the diet to maintain health. Required levels are between 425 mg/day (female) and 550 mg/day (male). Milk, eggs, liver, and peanuts are especially rich in choline. Most choline is found in phospholipids, namely phosphatidylcholine or lecithin. Choline can be oxidized to form betaine, which is a methyl source for many reactions (i.e. conversion of homocysteine into methionine). Lack of sufficient amounts of choline in the diet can lead to a fatty liver condition and general liver damage. This arises from the lack of VLDL, which is necessary to transport fats away from the liver. Choline deficiency also leads to elevated serum levels of alanine amino transferase and is associated with increased incidence of liver cancer. Nutritional supplement. Occurs free and combined in many animal and vegetable foods with highest concentrations found in egg yolk, meat, fish, milk, cereaks and legumes Choline. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=62-49-7 (retrieved 2024-06-29) (CAS RN: 62-49-7). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

   

Stachydrine

(2S)-1,1-dimethylpyrrolidin-1-ium-2-carboxylate

C7H13NO2 (143.0946)


Proline betaine is an osmoprotective compound found in urine. It is thought to serve an osmoprotective role for the kidney. Proline betaine is a glycine betaine analogue found in many citrus foods. Elevated levels of proline betaine in human urine are found after the consumption of citrus fruits and juices (PMID: 18060588). Proline betaine is a biomarker for the consumption of citrus fruits. Alkaloid from Citrus spp Medicago sativa and Stachys subspecies(alfalfa). L-Stachydrine or also called proline betaine is a biomarker for the consumption of citrus fruits. L-Stachydrine is found in many foods, some of which are capers, pulses, lemon, and alfalfa. Proline betaine, also known as stachydrine, belongs to the class of organic compounds known as proline and derivatives. Proline and derivatives are compounds containing proline or a derivative thereof resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. Proline betaine exists in all living organisms, ranging from bacteria to humans. Proline betaine is found, on average, in the highest concentration within capers (Capparis spinosa). Proline betaine has also been detected, but not quantified in, several different foods, such as soy beans (Glycine max), crosnes (Stachys affinis), domestic pigs (Sus scrofa domestica), limes (Citrus aurantiifolia), and triticales (X Triticosecale rimpaui). This could make proline betaine a potential biomarker for the consumption of these foods. Proline betaine is a secondary metabolite. Secondary metabolites are metabolically or physiologically non-essential metabolites that may serve a role as defense or signalling molecules. In some cases they are simply molecules that arise from the incomplete metabolism of other secondary metabolites. Based on a literature review a significant number of articles have been published on Proline betaine. Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-κB signal pathway. Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-κB signal pathway.

   

Cholesterol

(1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol

C27H46O (386.3548)


Cholesterol is a sterol (a combination steroid and alcohol) and a lipid found in the cell membranes of all body tissues and transported in the blood plasma of all animals. The name originates from the Greek chole- (bile) and stereos (solid), and the chemical suffix -ol for an alcohol. This is because researchers first identified cholesterol in solid form in gallstones in 1784. In the body, cholesterol can exist in either the free form or as an ester with a single fatty acid (of 10-20 carbons in length) covalently attached to the hydroxyl group at position 3 of the cholesterol ring. Due to the mechanism of synthesis, plasma cholesterol esters tend to contain relatively high proportions of polyunsaturated fatty acids. Most of the cholesterol consumed as a dietary lipid exists as cholesterol esters. Cholesterol esters have a lower solubility in water than cholesterol and are more hydrophobic. They are hydrolyzed by the pancreatic enzyme cholesterol esterase to produce cholesterol and free fatty acids. Cholesterol has vital structural roles in membranes and in lipid metabolism in general. It is a biosynthetic precursor of bile acids, vitamin D, and steroid hormones (glucocorticoids, estrogens, progesterones, androgens and aldosterone). In addition, it contributes to the development and functioning of the central nervous system, and it has major functions in signal transduction and sperm development. Cholesterol is a ubiquitous component of all animal tissues where much of it is located in the membranes, although it is not evenly distributed. The highest proportion of unesterified cholesterol is in the plasma membrane (roughly 30-50\\\\% of the lipid in the membrane or 60-80\\\\% of the cholesterol in the cell), while mitochondria and the endoplasmic reticulum have very low cholesterol contents. Cholesterol is also enriched in early and recycling endosomes, but not in late endosomes. The brain contains more cholesterol than any other organ where it comprises roughly a quarter of the total free cholesterol in the human body. Of all the organic constituents of blood, only glucose is present in a higher molar concentration than cholesterol. Cholesterol esters appear to be the preferred form for transport in plasma and as a biologically inert storage (de-toxified) form. They do not contribute to membranes but are packed into intracellular lipid particles. Cholesterol molecules (i.e. cholesterol esters) are transported throughout the body via lipoprotein particles. The largest lipoproteins, which primarily transport fats from the intestinal mucosa to the liver, are called chylomicrons. They carry mostly triglyceride fats and cholesterol that are from food, especially internal cholesterol secreted by the liver into the bile. In the liver, chylomicron particles give up triglycerides and some cholesterol. They are then converted into low-density lipoprotein (LDL) particles, which carry triglycerides and cholesterol on to other body cells. In healthy individuals, the LDL particles are large and relatively few in number. In contrast, large numbers of small LDL particles are strongly associated with promoting atheromatous disease within the arteries. (Lack of information on LDL particle number and size is one of the major problems of conventional lipid tests.). In conditions with elevated concentrations of oxidized LDL particles, especially small LDL particles, cholesterol promotes atheroma plaque deposits in the walls of arteries, a condition known as atherosclerosis, which is a major contributor to coronary heart disease and other forms of cardiovascular disease. There is a worldwide trend to believe that lower total cholesterol levels tend to correlate with lower atherosclerosis event rates (though some studies refute this idea). As a result, cholesterol has become a very large focus for the scientific community trying to determine the proper amount of cholesterol needed in a healthy diet. However, the primary association of atherosclerosis with c... Constituent either free or as esters, of fish liver oils, lard, dairy fats, egg yolk and bran Cholesterol is the major sterol in mammals. It is making up 20-25\\% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins[1][2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist[3]. Cholesterol is the major sterol in mammals. It is making up 20-25\% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins[1][2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist[3].

   

Choline

Choline

[C5H14NO]+ (104.1075)


D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D008082 - Lipotropic Agents D002491 - Central Nervous System Agents > D018697 - Nootropic Agents D009676 - Noxae > D000963 - Antimetabolites D005765 - Gastrointestinal Agents

   

Stachydrine

Pyrrolidinium, 2-carboxy-1,1-dimethyl-, inner salt, (2S)-

C7H13NO2 (143.0946)


L-proline betaine is an amino acid betaine that is L-proline zwitterion in which both of the hydrogens attached to the nitrogen are replaced by methyl groups. It has a role as a food component, a plant metabolite and a human blood serum metabolite. It is a N-methyl-L-alpha-amino acid, an alkaloid and an amino-acid betaine. It is functionally related to a L-prolinium. It is a conjugate base of a N,N-dimethyl-L-prolinium. It is an enantiomer of a D-proline betaine. Stachydrine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). Stachydrine is a natural product found in Teucrium polium, Halopithys incurva, and other organisms with data available. Proline betaine is an osmoprotective compound found in urine. It is thought to serve an osmoprotective role for the kidney. Proline betaine is a glycine betaine analogue found in many citrus foods. Elevated levels of proline betaine in human urine are found after the consumption of citrus fruits and juices (PMID: 18060588). Proline betaine is a biomarker for the consumption of citrus fruits. Alkaloid from Citrus spp Medicago sativa and Stachys subspecies(alfalfa). L-Stachydrine or also called proline betaine is a biomarker for the consumption of citrus fruits. L-Stachydrine is found in many foods, some of which are capers, pulses, lemon, and alfalfa. An amino acid betaine that is L-proline zwitterion in which both of the hydrogens attached to the nitrogen are replaced by methyl groups. Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-κB signal pathway. Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-κB signal pathway.

   

Betaine

2-(trimethylazaniumyl)acetate

C5H11NO2 (117.079)


Betaine or trimethylglycine is a methylated derivative of glycine. It functions as a methyl donor in that it carries and donates methyl functional groups to facilitate necessary chemical processes. The donation of methyl groups is important to proper liver function, cellular replication, and detoxification reactions. Betaine also plays a role in the manufacture of carnitine and serves to protect the kidneys from damage. Betaine has also been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th Ed, p1341). Betaine is found in many foods, some of which are potato puffs, poppy, hazelnut, and garden cress. Betaine. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=107-43-7 (retrieved 2024-06-28) (CAS RN: 107-43-7). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

   
   

Cholesterol

(1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol

C27H46O (386.3548)


A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group. Disclaimer: While authors make an effort to ensure that the content of this record is accurate, the authors make no representations or warranties in relation to the accuracy or completeness of the record. This record do not reflect any viewpoints of the affiliation and organization to which the authors belong. Cholesterol is the major sterol in mammals. It is making up 20-25\\% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins[1][2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist[3]. Cholesterol is the major sterol in mammals. It is making up 20-25\% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins[1][2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist[3].

   

Choline

Choline chloride

[C5H14NO]+ (104.1075)


MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; OEYIOHPDSNJKLS_STSL_0152_Choline_0125fmol_180430_S2_LC02_MS02_80; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I. MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I. D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D008082 - Lipotropic Agents D002491 - Central Nervous System Agents > D018697 - Nootropic Agents IPB_RECORD: 922; CONFIDENCE confident structure D009676 - Noxae > D000963 - Antimetabolites D005765 - Gastrointestinal Agents

   

Indole-3-carboxaldehyde

INDOLE-3-CARBOXYALDEHYDE

C9H7NO (145.0528)


Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1]. Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1].

   

p-Hydroxybenzaldehyde

p-Hydroxybenzaldehyde

C7H6O2 (122.0368)


p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.

   

4-Hydroxybenzaldehyde

4-Hydroxybenzaldehyde

C7H6O2 (122.0368)


p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.

   
   

Choline

Choline Hydroxide

C5H14NO+ (104.1075)


A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function. D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D008082 - Lipotropic Agents D002491 - Central Nervous System Agents > D018697 - Nootropic Agents D009676 - Noxae > D000963 - Antimetabolites D005765 - Gastrointestinal Agents

   
   

AI3-52407

5-21-08-00246 (Beilstein Handbook Reference)

C9H7NO (145.0528)


Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1]. Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin[1].

   

FR-0985

4-08-00-00251 (Beilstein Handbook Reference)

C7H6O2 (122.0368)


p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.

   

623-05-2

InChI=1\C7H8O2\c8-5-6-1-3-7(9)4-2-6\h1-4,8-9H,5H

C7H8O2 (124.0524)


4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth[1][2][3][4]. 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth[1][2][3][4].

   

Martefragin A

Martefragin A

C20H25N3O3 (355.1896)


An indole alkaloid isolated from the red alga Martensia fragilis and has been shown to inhibit lipid peroxidation.

   

2-(dimethylamino)-n-[3-(1h-indol-3-yl)-1-oxo-1-{[4-(sulfooxy)phenyl]methoxy}propan-2-yl]-4-methylhexanimidic acid

2-(dimethylamino)-n-[3-(1h-indol-3-yl)-1-oxo-1-{[4-(sulfooxy)phenyl]methoxy}propan-2-yl]-4-methylhexanimidic acid

C27H35N3O7S (545.2196)


   

2-{2-[1-(dimethylamino)-2-phenylethyl]-1,3-oxazole-5-carbonyl}aniline

2-{2-[1-(dimethylamino)-2-phenylethyl]-1,3-oxazole-5-carbonyl}aniline

C20H21N3O2 (335.1634)


   

methyl 2-(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acetate

methyl 2-(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acetate

C9H10O4 (182.0579)


   

(3r,4r,6s)-4-bromo-6-[(2r,3e)-4-bromo-2-hydroxybut-3-en-2-yl]-3-methyloxan-3-ol

(3r,4r,6s)-4-bromo-6-[(2r,3e)-4-bromo-2-hydroxybut-3-en-2-yl]-3-methyloxan-3-ol

C10H16Br2O3 (341.9466)


   

5-[(3e)-4-bromo-2-hydroxybut-3-en-2-yl]-2,2-dimethyloxolan-3-ol

5-[(3e)-4-bromo-2-hydroxybut-3-en-2-yl]-2,2-dimethyloxolan-3-ol

C10H17BrO3 (264.0361)


   

6-{[29-(2-hydroxy-3,5-dimethoxyphenyl)-10-({2-[5-(2-hydroxy-5,9,10-trimethyl-6-methylideneundec-10-en-2-yl)oxolan-2-yl]-5,9,10-trimethyl-6-methylideneundec-10-en-2-yl}oxy)nonacosan-9-yl]oxy}-2,4,4-trimethyl-3-[(1e,3e,5e,7e,9e,11e,13e,15e,17e)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex-1-en-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]cyclohex-2-en-1-one

6-{[29-(2-hydroxy-3,5-dimethoxyphenyl)-10-({2-[5-(2-hydroxy-5,9,10-trimethyl-6-methylideneundec-10-en-2-yl)oxolan-2-yl]-5,9,10-trimethyl-6-methylideneundec-10-en-2-yl}oxy)nonacosan-9-yl]oxy}-2,4,4-trimethyl-3-[(1e,3e,5e,7e,9e,11e,13e,15e,17e)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex-1-en-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]cyclohex-2-en-1-one

C111H178O8 (1639.3521)


   

[(1s)-1-[5-(1h-indol-3-yl)-1,3-oxazol-2-yl]-2-phenylethyl]dimethylamine

[(1s)-1-[5-(1h-indol-3-yl)-1,3-oxazol-2-yl]-2-phenylethyl]dimethylamine

C21H21N3O (331.1685)


   

(3r,3ar,6r,6ar)-3a,6-dihydroxy-3-[(4-hydroxyphenyl)methyl]-3-methoxy-dihydro-5h-furo[3,2-b]furan-2-one

(3r,3ar,6r,6ar)-3a,6-dihydroxy-3-[(4-hydroxyphenyl)methyl]-3-methoxy-dihydro-5h-furo[3,2-b]furan-2-one

C14H16O7 (296.0896)


   

(3s,5s)-5-[(2s,3e)-4-bromo-2-hydroxybut-3-en-2-yl]-2,2-dimethyloxolan-3-ol

(3s,5s)-5-[(2s,3e)-4-bromo-2-hydroxybut-3-en-2-yl]-2,2-dimethyloxolan-3-ol

C10H17BrO3 (264.0361)


   

(2s,3e)-4-bromo-2-[(2s,4s)-4-bromo-5,5-dimethyloxolan-2-yl]but-3-en-2-ol

(2s,3e)-4-bromo-2-[(2s,4s)-4-bromo-5,5-dimethyloxolan-2-yl]but-3-en-2-ol

C10H16Br2O2 (325.9517)


   

4-bromo-6-[(3e)-4-chloro-2-hydroxybut-3-en-2-yl]-3-methyloxan-3-ol

4-bromo-6-[(3e)-4-chloro-2-hydroxybut-3-en-2-yl]-3-methyloxan-3-ol

C10H16BrClO3 (297.9971)


   

n-[3-(1h-indol-3-yl)-1-oxo-1-{[4-(sulfooxy)phenyl]methoxy}propan-2-yl]-4-methyl-2-(methylamino)hexanimidic acid

n-[3-(1h-indol-3-yl)-1-oxo-1-{[4-(sulfooxy)phenyl]methoxy}propan-2-yl]-4-methyl-2-(methylamino)hexanimidic acid

C26H33N3O7S (531.2039)


   

5-(4-bromo-2-hydroxybut-3-en-2-yl)-2,2-dimethyloxolan-3-ol

5-(4-bromo-2-hydroxybut-3-en-2-yl)-2,2-dimethyloxolan-3-ol

C10H17BrO3 (264.0361)


   

(2r,3r,5s)-2-[(1e)-2-bromoethenyl]-5-(2-hydroxypropan-2-yl)-2-methyloxolan-3-ol

(2r,3r,5s)-2-[(1e)-2-bromoethenyl]-5-(2-hydroxypropan-2-yl)-2-methyloxolan-3-ol

C10H17BrO3 (264.0361)


   

(5e,8e,10e,12s,14e)-12-hydroxyicosa-5,8,10,14-tetraenoic acid

(5e,8e,10e,12s,14e)-12-hydroxyicosa-5,8,10,14-tetraenoic acid

C20H32O3 (320.2351)


   

(2s,3r,5s)-2-[(1e)-2-bromoethenyl]-5-(2-hydroxypropan-2-yl)-2-methyloxolan-3-ol

(2s,3r,5s)-2-[(1e)-2-bromoethenyl]-5-(2-hydroxypropan-2-yl)-2-methyloxolan-3-ol

C10H17BrO3 (264.0361)


   

6-{[31-(2-hydroxy-3,5-dimethoxyphenyl)-10-({2-[5-(2-hydroxy-5,9,10-trimethyl-6-methylideneundec-10-en-2-yl)oxolan-2-yl]-5,9,10-trimethyl-6-methylideneundec-10-en-2-yl}oxy)hentriacontan-9-yl]oxy}-2,4,4-trimethyl-3-[(1e,3e,5e,7e,9e,11e,13e,15e,17e)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex-1-en-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]cyclohex-2-en-1-one

6-{[31-(2-hydroxy-3,5-dimethoxyphenyl)-10-({2-[5-(2-hydroxy-5,9,10-trimethyl-6-methylideneundec-10-en-2-yl)oxolan-2-yl]-5,9,10-trimethyl-6-methylideneundec-10-en-2-yl}oxy)hentriacontan-9-yl]oxy}-2,4,4-trimethyl-3-[(1e,3e,5e,7e,9e,11e,13e,15e,17e)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex-1-en-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]cyclohex-2-en-1-one

C113H182O8 (1667.3834)


   

6-amino-6-carboxy-2-(trimethylammonio)hexanoate

6-amino-6-carboxy-2-(trimethylammonio)hexanoate

C10H20N2O4 (232.1423)


   

24-α-ethylcholesterol

24-α-ethylcholesterol

C29H50O (414.3861)


   

(4-ethoxyphenyl)methanol

(4-ethoxyphenyl)methanol

C9H12O2 (152.0837)


   

(2s,6r)-6-(2-chloropropan-2-yl)-2-(dibromomethyl)-3-methyl-5,6-dihydro-2h-pyran

(2s,6r)-6-(2-chloropropan-2-yl)-2-(dibromomethyl)-3-methyl-5,6-dihydro-2h-pyran

C10H15Br2ClO (343.9178)


   

(3r,4r,6s)-4-bromo-6-[(2s,3e)-4-chloro-2-hydroxybut-3-en-2-yl]-3-methyloxan-3-ol

(3r,4r,6s)-4-bromo-6-[(2s,3e)-4-chloro-2-hydroxybut-3-en-2-yl]-3-methyloxan-3-ol

C10H16BrClO3 (297.9971)


   

(3ar,3br,9ar,9bs,11ar)-1-(5-ethyl-6-methylheptan-2-yl)-9a,11a-dimethyl-1h,2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-ol

(3ar,3br,9ar,9bs,11ar)-1-(5-ethyl-6-methylheptan-2-yl)-9a,11a-dimethyl-1h,2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-7-ol

C29H50O (414.3861)


   

(2r,3e)-4-bromo-2-[(2s,4s)-4-bromo-5,5-dimethyloxolan-2-yl]but-3-en-2-ol

(2r,3e)-4-bromo-2-[(2s,4s)-4-bromo-5,5-dimethyloxolan-2-yl]but-3-en-2-ol

C10H16Br2O2 (325.9517)


   

(2r,3s,5s)-2-[(1e)-2-bromoethenyl]-5-(2-hydroxypropan-2-yl)-2-methyloxolan-3-ol

(2r,3s,5s)-2-[(1e)-2-bromoethenyl]-5-(2-hydroxypropan-2-yl)-2-methyloxolan-3-ol

C10H17BrO3 (264.0361)


   

(2s,4s)-n-[(2s)-3-(1h-indol-3-yl)-1-oxo-1-{[4-(sulfooxy)phenyl]methoxy}propan-2-yl]-4-methyl-2-(methylamino)hexanimidic acid

(2s,4s)-n-[(2s)-3-(1h-indol-3-yl)-1-oxo-1-{[4-(sulfooxy)phenyl]methoxy}propan-2-yl]-4-methyl-2-(methylamino)hexanimidic acid

C26H33N3O7S (531.2039)


   

5-(1,2-dihydroxyethyl)-3-[(4-hydroxyphenyl)methyl]-3-methoxyoxolane-2,4-dione

5-(1,2-dihydroxyethyl)-3-[(4-hydroxyphenyl)methyl]-3-methoxyoxolane-2,4-dione

C14H16O7 (296.0896)


   

(3e)-4-bromo-2-(4-bromo-5,5-dimethyloxolan-2-yl)but-3-en-2-ol

(3e)-4-bromo-2-(4-bromo-5,5-dimethyloxolan-2-yl)but-3-en-2-ol

C10H16Br2O2 (325.9517)


   

(2r,3e)-4-bromo-2-[(2s,4r)-4-bromo-5,5-dimethyloxolan-2-yl]but-3-en-2-ol

(2r,3e)-4-bromo-2-[(2s,4r)-4-bromo-5,5-dimethyloxolan-2-yl]but-3-en-2-ol

C10H16Br2O2 (325.9517)


   

(2r,6r)-6-(2-chloropropan-2-yl)-2-(dibromomethyl)-3-methyl-5,6-dihydro-2h-pyran

(2r,6r)-6-(2-chloropropan-2-yl)-2-(dibromomethyl)-3-methyl-5,6-dihydro-2h-pyran

C10H15Br2ClO (343.9178)


   

(3r,5s)-5-[(2r,3e)-4-bromo-2-hydroxybut-3-en-2-yl]-2,2-dimethyloxolan-3-ol

(3r,5s)-5-[(2r,3e)-4-bromo-2-hydroxybut-3-en-2-yl]-2,2-dimethyloxolan-3-ol

C10H17BrO3 (264.0361)


   

(3r,4r,6s)-4-bromo-6-[(2r,3e)-4-chloro-2-hydroxybut-3-en-2-yl]-3-methyloxan-3-ol

(3r,4r,6s)-4-bromo-6-[(2r,3e)-4-chloro-2-hydroxybut-3-en-2-yl]-3-methyloxan-3-ol

C10H16BrClO3 (297.9971)


   

3a,6-dihydroxy-3-[(4-hydroxyphenyl)methyl]-3-methoxy-dihydro-5h-furo[3,2-b]furan-2-one

3a,6-dihydroxy-3-[(4-hydroxyphenyl)methyl]-3-methoxy-dihydro-5h-furo[3,2-b]furan-2-one

C14H16O7 (296.0896)


   

n-(2-{2-[1-(dimethylamino)-2-phenylethyl]-1,3-oxazole-5-carbonyl}phenyl)carboximidic acid

n-(2-{2-[1-(dimethylamino)-2-phenylethyl]-1,3-oxazole-5-carbonyl}phenyl)carboximidic acid

C21H21N3O3 (363.1583)


   

(2s,4s)-2-(dimethylamino)-n-[(2s)-3-(1h-indol-3-yl)-1-oxo-1-{[4-(sulfooxy)phenyl]methoxy}propan-2-yl]-4-methylhexanimidic acid

(2s,4s)-2-(dimethylamino)-n-[(2s)-3-(1h-indol-3-yl)-1-oxo-1-{[4-(sulfooxy)phenyl]methoxy}propan-2-yl]-4-methylhexanimidic acid

C27H35N3O7S (545.2196)


   

1,1-dimethylpyrrolidin-1-ium-2-carboxylate

1,1-dimethylpyrrolidin-1-ium-2-carboxylate

C7H13NO2 (143.0946)


   

24-α-methylcholesterol

24-α-methylcholesterol

C28H48O (400.3705)


   

4-bromo-6-(4-bromo-2-hydroxybut-3-en-2-yl)-3-methyloxan-3-ol

4-bromo-6-(4-bromo-2-hydroxybut-3-en-2-yl)-3-methyloxan-3-ol

C10H16Br2O3 (341.9466)


   

2-[(1e)-2-bromoethenyl]-5-(2-hydroxypropan-2-yl)-2-methyloxolan-3-ol

2-[(1e)-2-bromoethenyl]-5-(2-hydroxypropan-2-yl)-2-methyloxolan-3-ol

C10H17BrO3 (264.0361)


   

(3s,5s)-5-[(2r,3e)-4-bromo-2-hydroxybut-3-en-2-yl]-2,2-dimethyloxolan-3-ol

(3s,5s)-5-[(2r,3e)-4-bromo-2-hydroxybut-3-en-2-yl]-2,2-dimethyloxolan-3-ol

C10H17BrO3 (264.0361)


   

(2s)-2-(dimethylamino)-n-[2-(1h-indol-3-yl)-2-oxoethyl]-3-phenylpropanimidic acid

(2s)-2-(dimethylamino)-n-[2-(1h-indol-3-yl)-2-oxoethyl]-3-phenylpropanimidic acid

C21H23N3O2 (349.179)


   

(3r,5r)-5-[(1r)-1,2-dihydroxyethyl]-3-[(4-hydroxyphenyl)methyl]-3-methoxyoxolane-2,4-dione

(3r,5r)-5-[(1r)-1,2-dihydroxyethyl]-3-[(4-hydroxyphenyl)methyl]-3-methoxyoxolane-2,4-dione

C14H16O7 (296.0896)


   

(5z,7e)-8-[(1z,3z,6z)-dodeca-1,3,6-trien-1-yloxy]octa-5,7-dienoic acid

(5z,7e)-8-[(1z,3z,6z)-dodeca-1,3,6-trien-1-yloxy]octa-5,7-dienoic acid

C20H30O3 (318.2195)


   

4-bromo-2-(4-bromo-5,5-dimethyloxolan-2-yl)but-3-en-2-ol

4-bromo-2-(4-bromo-5,5-dimethyloxolan-2-yl)but-3-en-2-ol

C10H16Br2O2 (325.9517)


   

4-bromo-6-[(3e)-4-bromo-2-hydroxybut-3-en-2-yl]-3-methyloxan-3-ol

4-bromo-6-[(3e)-4-bromo-2-hydroxybut-3-en-2-yl]-3-methyloxan-3-ol

C10H16Br2O3 (341.9466)


   

(5z,7s)-7-hydroxy-7-[(2s,3s)-3-[(2z,5z)-undeca-2,5-dien-1-yl]oxiran-2-yl]hept-5-enoic acid

(5z,7s)-7-hydroxy-7-[(2s,3s)-3-[(2z,5z)-undeca-2,5-dien-1-yl]oxiran-2-yl]hept-5-enoic acid

C20H32O4 (336.23)


   

(5z,7r)-7-hydroxy-7-[(2s,3s)-3-[(2z,5z)-undeca-2,5-dien-1-yl]oxiran-2-yl]hept-5-enoic acid

(5z,7r)-7-hydroxy-7-[(2s,3s)-3-[(2z,5z)-undeca-2,5-dien-1-yl]oxiran-2-yl]hept-5-enoic acid

C20H32O4 (336.23)