Isorhamnetin (BioDeep_00000000852)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-

化学式: C16H12O7 (316.0583)
中文名称: 3-O-甲基槲皮素, 3-邻甲基槲皮素
谱图信息: 最多检出来源 Viridiplantae(plant) 18.19%

分子结构信息

SMILES: C1(O)=CC2OC(C3C=C(O)C(O)=CC=3)=C(OC)C(=O)C=2C(O)=C1
InChI: InChI=1S/C16H12O7/c1-22-16-14(21)13-11(20)5-8(17)6-12(13)23-15(16)7-2-3-9(18)10(19)4-7/h2-6,17-20H,1H3

描述信息

3,4,5,7-tetrahydroxy-3-methoxyflavone is a tetrahydroxyflavone having the 4-hydroxy groups located at the 3- 4- 5- and 7-positions as well as a methoxy group at the 2-position. It has a role as a metabolite and an antimicrobial agent. It is a tetrahydroxyflavone and a monomethoxyflavone. It is functionally related to a quercetin. It is a conjugate acid of a 3,4,5-trihydroxy-3-methoxyflavon-7-olate.
3-O-Methylquercetin is a natural product found in Lotus ucrainicus, Wollastonia biflora, and other organisms with data available.
See also: Tobacco Leaf (part of).
3-O-Methylquercetin (3-MQ), a main constituent of Rhamnus nakaharai, inhibits total cAMP and cGMP-phosphodiesterase (PDE) of guinea pig trachealis. 3-O-Methylquercetin (3-MQ) exhibits IC50 values ranging from 1.6-86.9 μM for PDE isozymes (PDE1-5)[1].
3-O-Methylquercetin (3-MQ), a main constituent of Rhamnus nakaharai, inhibits total cAMP and cGMP-phosphodiesterase (PDE) of guinea pig trachealis. 3-O-Methylquercetin (3-MQ) exhibits IC50 values ranging from 1.6-86.9 μM for PDE isozymes (PDE1-5)[1].

同义名列表

37 个代谢物同义名

4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-1-benzopyran-4-one; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-1-benzopyran-4-one); 4H-1-Benzopyran-4-one,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxychromen-4-one; Flavone, 3,4,5,7-tetrahydroxy-3-methoxy-; 3,4,5,7-tetrahydroxy-3-methoxy-flavone; 5,7,3,4-Tetrahydroxy-3-methoxyflavone; 3,4,5,7-Tetrahydroxy-3-methoxyflavone; Flavone,4,5,7-tetrahydroxy-3-methoxy-; 3-Methoxy-3,4,5,7-tetrahydroxyflavone; 3-Methoxy-5,7,3,4-tetrahydroxyflavone; 3,4,5,7-tetrahydroxy-3-methoxyflavone; 3-O-Methylquercetin, >=97\\% (HPLC); QUERCETIN 3-MONOMETHYL ETHER; Quercetin-3-O-methyl ether; Quercetin 3-O-methyl ether; Quercetin-3-methyl ether; Quercetin 3-methyl ether; METHYLQUERCETIN, 3-O-; 3-O-Methyl Quercetin; 3-O-methylquercetin; 3-methyl-quercetin; 3-Methylquercetol; 3-methylquercetin; 3-Methoxyluteolin; UNII-7J92C373RH; isorhamnetine; iso-rhamnetin; MEGxp0_000771; Oprea1_264124; ACon1_000818; Isorhamnetin; 7J92C373RH; 3-O-MQ



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1011 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 CASP3, CASP7, CASP9, CAT, CCND1, EGFR, ERBB2, MAPK14, MTOR, NOS2, PIK3CA, XDH
Peripheral membrane protein 1 MTOR
Endosome membrane 2 EGFR, ERBB2
Endoplasmic reticulum membrane 2 EGFR, MTOR
Nucleus 10 CASP3, CASP7, CASP9, CCND1, EGFR, ERBB2, JUND, MAPK14, MTOR, NOS2
cytosol 11 CASP3, CASP7, CASP9, CAT, CCND1, ERBB2, MAPK14, MTOR, NOS2, PIK3CA, XDH
dendrite 1 MTOR
phagocytic vesicle 1 MTOR
centrosome 1 CCND1
nucleoplasm 8 CASP3, CASP7, CCND1, ERBB2, JUND, MAPK14, MTOR, NOS2
RNA polymerase II transcription regulator complex 1 JUND
Cell membrane 3 EGFR, ERBB2, TNF
Cytoplasmic side 1 MTOR
lamellipodium 1 PIK3CA
ruffle membrane 2 EGFR, ERBB2
Early endosome membrane 1 EGFR
Golgi apparatus membrane 1 MTOR
cell junction 1 EGFR
cell surface 2 EGFR, TNF
glutamatergic synapse 3 CASP3, EGFR, MAPK14
Golgi membrane 3 EGFR, INS, MTOR
lysosomal membrane 2 GAA, MTOR
neuromuscular junction 1 ERBB2
neuronal cell body 2 CASP3, TNF
presynaptic membrane 1 ERBB2
Cytoplasm, cytosol 2 CASP7, NOS2
Lysosome 2 GAA, MTOR
endosome 1 EGFR
plasma membrane 6 EGFR, ERBB2, GAA, NOS2, PIK3CA, TNF
Membrane 5 CAT, EGFR, ERBB2, GAA, MTOR
apical plasma membrane 2 EGFR, ERBB2
basolateral plasma membrane 2 EGFR, ERBB2
extracellular exosome 3 CAT, GAA, SOD2
Lysosome membrane 2 GAA, MTOR
extracellular space 8 CASP7, EGFR, IL4, IL5, IL6, INS, TNF, XDH
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 4 EGFR, ERBB2, NOS2, PIK3CA
bicellular tight junction 1 CCND1
intercalated disc 1 PIK3CA
mitochondrion 4 CASP9, CAT, MAPK14, SOD2
protein-containing complex 3 CASP9, CAT, EGFR
intracellular membrane-bounded organelle 2 CAT, GAA
Microsome membrane 1 MTOR
postsynaptic density 1 CASP3
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 2 EGFR, ERBB2
Secreted 5 GAA, IL4, IL5, IL6, INS
extracellular region 9 CAT, ERBB2, GAA, IL4, IL5, IL6, INS, MAPK14, TNF
Mitochondrion outer membrane 1 MTOR
mitochondrial outer membrane 1 MTOR
Mitochondrion matrix 1 SOD2
mitochondrial matrix 2 CAT, SOD2
transcription regulator complex 1 JUND
Nucleus membrane 1 CCND1
nuclear membrane 2 CCND1, EGFR
external side of plasma membrane 1 TNF
cytoplasmic vesicle 1 ERBB2
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
Early endosome 1 ERBB2
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Cell projection, ruffle membrane 1 ERBB2
Cytoplasm, perinuclear region 2 ERBB2, NOS2
Membrane raft 2 EGFR, TNF
focal adhesion 2 CAT, EGFR
mitochondrial nucleoid 1 SOD2
Peroxisome 3 CAT, NOS2, XDH
intracellular vesicle 1 EGFR
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 2 CAT, NOS2
peroxisomal membrane 1 CAT
Nucleus, PML body 1 MTOR
PML body 1 MTOR
nuclear speck 1 MAPK14
receptor complex 2 EGFR, ERBB2
chromatin 1 JUND
phagocytic cup 1 TNF
Secreted, extracellular space 1 CASP7
spindle pole 1 MAPK14
nuclear envelope 1 MTOR
Endomembrane system 1 MTOR
endosome lumen 1 INS
tertiary granule membrane 1 GAA
myelin sheath 1 ERBB2
basal plasma membrane 2 EGFR, ERBB2
synaptic membrane 1 EGFR
ficolin-1-rich granule lumen 2 CAT, MAPK14
secretory granule lumen 3 CAT, INS, MAPK14
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 IL6, INS
transcription repressor complex 2 CCND1, JUND
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
transport vesicle 1 INS
azurophil granule membrane 1 GAA
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
apoptosome 1 CASP9
semaphorin receptor complex 1 ERBB2
clathrin-coated endocytic vesicle membrane 1 EGFR
ficolin-1-rich granule membrane 1 GAA
death-inducing signaling complex 1 CASP3
[Isoform 1]: Cell membrane 1 ERBB2
Cytoplasmic vesicle, phagosome 1 MTOR
cyclin-dependent protein kinase holoenzyme complex 1 CCND1
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
transcription factor AP-1 complex 1 JUND
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
cortical cytoskeleton 1 NOS2
catalase complex 1 CAT
ERBB3:ERBB2 complex 1 ERBB2
interleukin-6 receptor complex 1 IL6
autolysosome lumen 1 GAA
cyclin D1-CDK4 complex 1 CCND1
cyclin D1-CDK6 complex 1 CCND1
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
caspase complex 1 CASP9
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Jia Jian, Li Yu-Qing, Han Rang-Yue, Zhong Xia, Xie Ke-Huan, Yan Ying, Wang Li, Tan Rui-Zhi. Isorhamnetin ameliorates cisplatin-induced acute kidney injury in mice by activating SLPI-mediated anti-inflammatory effect in macrophage. Immunopharmacology and immunotoxicology. 2024 Jun; 46(3):319-329. doi: 10.1080/08923973.2024.2329621. [PMID: 38466121]
  • Xiaojuan Li, Tao Wang, Qilong Zhou, Fan Li, Ting Liu, Kun Zhang, Ao Wen, Lijuan Feng, Xiaoling Shu, Simin Tian, Yijiang Liu, Yu Gao, Qing Xia, Guang Xin, Wen Huang. Isorhamnetin Alleviates Mitochondrial Injury in Severe Acute Pancreatitis via Modulation of KDM5B/HtrA2 Signaling Pathway. International journal of molecular sciences. 2024 Mar; 25(7):. doi: 10.3390/ijms25073784. [PMID: 38612598]
  • Lingkun Wang, Yaochen Xie, Boneng Xiao, Xuelin He, Guanghui Ying, Huiyan Zha, Chen Yang, Xuejin Jin, Guilin Li, Li Ping, Jincheng Wang, Qinjie Weng. Isorhamnetin alleviates cisplatin-induced acute kidney injury via enhancing fatty acid oxidation. Free radical biology & medicine. 2024 Feb; 212(?):22-33. doi: 10.1016/j.freeradbiomed.2023.12.010. [PMID: 38101584]
  • Xue-Feng Shi, Qi Yu, Kai-Bo Wang, Yi-Dong Fu, Shun Zhang, Zhen-Yun Liao, Yan Li, Ting Cai. Active ingredients Isorhamnetin of Croci Srigma inhibit stomach adenocarcinomas progression by MAPK/mTOR signaling pathway. Scientific reports. 2023 08; 13(1):12607. doi: 10.1038/s41598-023-39627-z. [PMID: 37537191]
  • Hong Wang, Lijia Chen, Binrui Yang, Jun Du, Liang Chen, Yiming Li, Fujiang Guo. Structures, Sources, Identification/Quantification Methods, Health Benefits, Bioaccessibility, and Products of Isorhamnetin Glycosides as Phytonutrients. Nutrients. 2023 Apr; 15(8):. doi: 10.3390/nu15081947. [PMID: 37111165]
  • Tianshu Yang, Yi Xiao, Shuo Liu, Fazhen Luo, Dongyun Tang, Yilin Yu, Yan Xie. Isorhamnetin induces cell cycle arrest and apoptosis by triggering DNA damage and regulating the AMPK/mTOR/p70S6K signaling pathway in doxorubicin-resistant breast cancer. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Mar; 114(?):154780. doi: 10.1016/j.phymed.2023.154780. [PMID: 37004402]
  • Peng Zhang, Yisheng Sun, Lei Shi, Dekang Sun, Lin Wang, Dongdong Feng, Chao Ding. Effect of isorhamnetin on carbonic anhydrase IX expression and tumorigenesis of bladder cancer by activating PPARγ/PTEN/AKT pathway. Tissue & cell. 2023 Mar; 82(?):102048. doi: 10.1016/j.tice.2023.102048. [PMID: 36905861]
  • Fei Yu, Yanfeng Xue, Yunyan Zhao, Long Zhang, Xiao He, Zheng Liu. Isorhamnetin inhibits inflammatory response to alleviate DHEA-induced polycystic ovary syndrome in rats. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 2023 Feb; ?(?):2183045. doi: 10.1080/09513590.2023.2183045. [PMID: 36842967]
  • Maitane González-Arceo, Iván Gomez-Lopez, Helen Carr-Ugarte, Itziar Eseberri, Marcela González, M Pilar Cano, María P Portillo, Saioa Gómez-Zorita. Anti-Obesity Effects of Isorhamnetin and Isorhamnetin Conjugates. International journal of molecular sciences. 2022 Dec; 24(1):. doi: 10.3390/ijms24010299. [PMID: 36613743]
  • Anna Stochmal, Agata Rolnik, Bartosz Skalski, Jerzy Zuchowski, Beata Olas. Antiplatelet and Anticoagulant Activity of Isorhamnetin and Its Derivatives Isolated from Sea Buckthorn Berries, Measured in Whole Blood. Molecules (Basel, Switzerland). 2022 Jul; 27(14):. doi: 10.3390/molecules27144429. [PMID: 35889302]
  • Vanessa Pittol, Kleyton Santos Veras, Eduarda Doneda, Ariane Dorneles Silva, Maria Gabriele Delagustin, Letícia Scherer Koester, Valquíria Linck Bassani. The challenge of flavonoid/cyclodextrin complexation in a complex matrix of the quercetin, luteolin, and 3-O-methylquercetin. Pharmaceutical development and technology. 2022 Jul; 27(6):625-634. doi: 10.1080/10837450.2022.2098326. [PMID: 35796030]
  • Huseyin Gungor, Mehmet Ekici, Mehmet Burak Ates. Lipid-lowering, anti-inflammatory, and hepatoprotective effects of isorhamnetin on acetaminophen-induced hepatotoxicity in mice. Drug and chemical toxicology. 2022 May; ?(?):1-9. doi: 10.1080/01480545.2022.2069256. [PMID: 35502492]
  • Feten Zar Kalai, Mondher Boulaaba, Farhana Ferdousi, Hiroko Isoda. Effects of Isorhamnetin on Diabetes and Its Associated Complications: A Review of In Vitro and In Vivo Studies and a Post Hoc Transcriptome Analysis of Involved Molecular Pathways. International journal of molecular sciences. 2022 Jan; 23(2):. doi: 10.3390/ijms23020704. [PMID: 35054888]
  • Fuqi Wang, Xu Zhao, Xin Su, Danni Song, Fengmao Zou, Lina Fang. Isorhamnetin, the xanthine oxidase inhibitor from Sophora japonica, ameliorates uric acid levels and renal function in hyperuricemic mice. Food & function. 2021 Dec; 12(24):12503-12512. doi: 10.1039/d1fo02719k. [PMID: 34806108]
  • Yingzhuan Zhan, Wenjing Ta, Wenjuan Tang, Ruochen Hua, Jue Wang, Cheng Wang, Wen Lu. Potential antiviral activity of isorhamnetin against SARS-CoV-2 spike pseudotyped virus in vitro. Drug development research. 2021 12; 82(8):1124-1130. doi: 10.1002/ddr.21815. [PMID: 33847382]
  • M Antunes-Ricardo, D Guardado-Félix, M R Rocha-Pizaña, J Garza-Martínez, L Acevedo-Pacheco, J A Gutiérrez-Uribe, J Villela-Castrejón, F López-Pacheco, S O Serna-Saldívar. Opuntia ficus-indica Extract and Isorhamnetin-3-O-Glucosyl-Rhamnoside Diminish Tumor Growth of Colon Cancer Cells Xenografted in Immune-Suppressed Mice through the Activation of Apoptosis Intrinsic Pathway. Plant foods for human nutrition (Dordrecht, Netherlands). 2021 Dec; 76(4):434-441. doi: 10.1007/s11130-021-00934-3. [PMID: 34786663]
  • Haowen Li, Manzhen Li, Jingxin Fu, Hui Ao, Weihua Wang, Xiangtao Wang. Enhancement of oral bioavailability of quercetin by metabolic inhibitory nanosuspensions compared to conventional nanosuspensions. Drug delivery. 2021 Dec; 28(1):1226-1236. doi: 10.1080/10717544.2021.1927244. [PMID: 34142631]
  • Aiziguli Mulati, Xin Zhang, Tong Zhao, Bo Ren, Luanfeng Wang, Xiaoning Liu, Ying Lan, Xuebo Liu. Isorhamnetin attenuates high-fat and high-fructose diet induced cognitive impairments and neuroinflammation by mediating MAPK and NFκB signaling pathways. Food & function. 2021 Oct; 12(19):9261-9272. doi: 10.1039/d0fo03165h. [PMID: 34606526]
  • Eduarda Doneda, Sara Elis Bianchi, Vanessa Pittol, Tainá Kreutz, Juliete Nathali Scholl, Irene L Ibañez, Candelaria Bracalente, Hebe Durán, Fabrício Figueiró, Fábio Klamt, Valquiria Linck Bassani. 3-O-Methylquercetin from Achyrocline satureioides-cytotoxic activity against A375-derived human melanoma cell lines and its incorporation into cyclodextrins-hydrogels for topical administration. Drug delivery and translational research. 2021 10; 11(5):2151-2168. doi: 10.1007/s13346-020-00882-6. [PMID: 33410099]
  • Ece Sevgi, Aydan Dag, Çağla Kızılarslan-Hançer, Sezen Atasoy, Belma Zengin Kurt, Öznur Aksakal. Evaluation of cytotoxic and antioxidant potential of Dittrichia viscosa (L.) Greuter used in traditional medicine. Journal of ethnopharmacology. 2021 Aug; 276(?):114211. doi: 10.1016/j.jep.2021.114211. [PMID: 34015367]
  • Ahmed A Zaki, Xiaoqian Xu, Yuewen Wang, Pei-Hsin Shie, Longxin Qiu. A new anti-inflammatory flavonoid glycoside from tetraena aegyptia. Natural product research. 2021 Jun; 35(12):1985-1990. doi: 10.1080/14786419.2019.1650356. [PMID: 31397172]
  • Ling Li, Xiao-Jie Jin, Jia-Wei Li, Cheng-Hao Li, Shuang-Yan Zhou, Jun-Jie Li, Cai-Qin Feng, Dong-Ling Liu, Yong-Qi Liu. Systematic insight into the active constituents and mechanism of Guiqi Baizhu for the treatment of gastric cancer. Cancer science. 2021 May; 112(5):1772-1784. doi: 10.1111/cas.14851. [PMID: 33682294]
  • Fei Chen, Minwei Hu, Yue Shen, Wenjun Zhu, Ailin Cao, Bin Ni, Jiao Qian, Jun Yang. Isorhamnetin promotes functional recovery in rats with spinal cord injury by abating oxidative stress and modulating M2 macrophages/microglia polarization. European journal of pharmacology. 2021 Mar; 895(?):173878. doi: 10.1016/j.ejphar.2021.173878. [PMID: 33453223]
  • Marwa Matboli, Doaa Ibrahim, Amany H Hasanin, Mohamed K Hassan, Eman K Habib, Miram M Bekhet, Ahmed M Afifi, Sanaa Eissa. Epigenetic modulation of autophagy genes linked to diabetic nephropathy by administration of isorhamnetin in Type 2 diabetes mellitus rats. Epigenomics. 2021 02; 13(3):187-202. doi: 10.2217/epi-2020-0353. [PMID: 33406900]
  • Jordan M Chapman, Gloria K Muday. Flavonols modulate lateral root emergence by scavenging reactive oxygen species in Arabidopsis thaliana. The Journal of biological chemistry. 2021 Jan; 296(?):100222. doi: 10.1074/jbc.ra120.014543. [PMID: 33839683]
  • Sara E Bianchi, Melissa A Pegues, Camila K Dias, Francesca Mascia, Eduarda Doneda, Vanessa Pittol, V Ashutosh Rao, Fábio Klamt, Valquiria L Bassani. Achyrocline satureioides compounds, achyrobichalcone and 3-O-methylquercetin, induce mitochondrial dysfunction and apoptosis in human breast cancer cell lines. IUBMB life. 2020 10; 72(10):2133-2145. doi: 10.1002/iub.2348. [PMID: 32710804]
  • Zhi Chang, Jia-Ling Wang, Zhi-Cheng Jing, Ping Ma, Qing-Bing Xu, Jian-Rong Na, Jie Tian, Xuan Ma, Wei Zhou, Ru Zhou. Protective effects of isorhamnetin on pulmonary arterial hypertension: in vivo and in vitro studies. Phytotherapy research : PTR. 2020 Oct; 34(10):2730-2744. doi: 10.1002/ptr.6714. [PMID: 32452118]
  • Gang Gong, Ying-Yun Guan, Zhong-Lin Zhang, Khalid Rahman, Su-Juan Wang, Shuang Zhou, Xin Luan, Hong Zhang. Isorhamnetin: A review of pharmacological effects. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2020 Aug; 128(?):110301. doi: 10.1016/j.biopha.2020.110301. [PMID: 32502837]
  • Jeffrey P Davis, Mihoko Koyanagi, Robert R Maronpot, Leslie Recio, Shim-Mo Hayashi. Identification of compound causing yellow bone discoloration following alpha-glycosyl isoquercitrin exposure in Sprague-Dawley rats. Archives of toxicology. 2020 07; 94(7):2413-2421. doi: 10.1007/s00204-020-02760-z. [PMID: 32388820]
  • Maiko Sakai, Kohta Ohnishi, Masashi Masuda, Hirokazu Ohminami, Hisami Yamanaka-Okumura, Taichi Hara, Yutaka Taketani. Isorhamnetin, a 3'-methoxylated flavonol, enhances the lysosomal proteolysis in J774.1 murine macrophages in a TFEB-independent manner. Bioscience, biotechnology, and biochemistry. 2020 Jun; 84(6):1221-1231. doi: 10.1080/09168451.2020.1727309. [PMID: 32046625]
  • Edgar Jesús Delgado-Núñez, Alejandro Zamilpa, Manasés González-Cortazar, Agustín Olmedo-Juárez, Alexandre Cardoso-Taketa, Ernesto Sánchez-Mendoza, Daniel Tapia-Maruri, David Osvaldo Salinas-Sánchez, Pedro Mendoza-de Gives. Isorhamnetin: A Nematocidal Flavonoid from Prosopis Laevigata Leaves Against Haemonchus Contortus Eggs and Larvae. Biomolecules. 2020 05; 10(5):. doi: 10.3390/biom10050773. [PMID: 32429307]
  • Cristian López-Palacios, Cecilia B Peña-Valdivia. Screening of secondary metabolites in cladodes to further decode the domestication process in the genus Opuntia (Cactaceae). Planta. 2020 Mar; 251(4):74. doi: 10.1007/s00425-020-03371-9. [PMID: 32144512]
  • Debanjana Bhattacharya, Ritam Sinha, Priyadarshini Mukherjee, Debaki Ranjan Howlader, Dhrubajyoti Nag, Soumyadev Sarkar, Hemanta Koley, Jeffrey H Withey, Ratan Gachhui. Anti-virulence activity of polyphenolic fraction isolated from Kombucha against Vibrio cholerae. Microbial pathogenesis. 2020 Mar; 140(?):103927. doi: 10.1016/j.micpath.2019.103927. [PMID: 31846743]
  • Wei-Chen Xiong, He-Zhen Wu, Yi-Yi Xiong, Bo Liu, Zhou-Tao Xie, Song-Tao Wu, Yun-Feng Yao, Yan-Fang Yang. Network Pharmacology-based Research of Active Components of Albiziae Flos and Mechanisms of Its Antidepressant Effect. Current medical science. 2020 Feb; 40(1):123-129. doi: 10.1007/s11596-020-2155-7. [PMID: 32166674]
  • Maja Budeč, Jasna Bošnir, Aleksandar Racz, Dario Lasić, Danijel Brkić, Ana Mosović Ćuić, Željka Kuharić, Gordana Jurak, Lidija Barušić. VERIFICATION OF AUTHENTICITY OF GINKGO BILOBA L. LEAF EXTRACT AND ITS PRODUCTS PRESENT ON THE CROATIAN MARKET BY ANALYSIS OF QUANTITY AND RATIO OF GINKGO FLAVONE GLYCOSIDES (QUERCETIN, KAEMPFEROL AND ISORHAMNETIN) TO TERPENE TRILACTONES TO THE EFFECT OF UNMASKING COUNTERFEIT DRUGS ENDANGERING PATIENT HEALTH. Acta clinica Croatica. 2019 Dec; 58(4):672-692. doi: 10.20471/acc.2019.58.04.15. [PMID: 32595253]
  • Elhadi E Elamir, Abdulrhman A Almadiy, Gomah E Nenaah, Abdullah A Alabas, Hajer S Alsaqri. Comparing six mathematical link function models of the antifeedant activity of lesser grain borer exposed to sub-lethal concentrations of some extracts from calotropis procera. Bioengineered. 2019 12; 10(1):292-305. doi: 10.1080/21655979.2019.1641399. [PMID: 31284815]
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