Caffeic Acid (BioDeep_00000398289)

Main id: BioDeep_00000000252

Secondary id: BioDeep_00000027880, BioDeep_00000398020, BioDeep_00000859476

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


3,4-dihydroxy cinnamic acid

化学式: C9H8O4 (180.0423)
中文名称: 咖啡酸, 3,4-二羟基肉桂酸
谱图信息: 最多检出来源 Homo sapiens(blood) 19.03%

分子结构信息

SMILES: C1=CC(=C(C=C1/C=C\C(=O)O)O)O
InChI: InChI=1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)

描述信息

A hydroxycinnamic acid that is cinnamic acid in which the phenyl ring is substituted by hydroxy groups at positions 3 and 4. It exists in cis and trans forms; the latter is the more common.
3,4-dihydroxycinnamic acid, also known as caffeic acid or trans-caffeate, is a member of the class of compounds known as hydroxycinnamic acids. Hydroxycinnamic acids are compounds containing an cinnamic acid where the benzene ring is hydroxylated. 3,4-dihydroxycinnamic acid is slightly soluble (in water) and a weakly acidic compound (based on its pKa). 3,4-dihydroxycinnamic acid can be found in fats and oils and nuts, which makes 3,4-dihydroxycinnamic acid a potential biomarker for the consumption of these food products. 3,4-dihydroxycinnamic acid exists in all eukaryotes, ranging from yeast to humans. Caffeic acid is an organic compound that is classified as a hydroxycinnamic acid. This yellow solid consists of both phenolic and acrylic functional groups. It is found in all plants because it is a key intermediate in the biosynthesis of lignin, one of the principal components of plant biomass and its residues .
Caffeic acid is a polyphenol present in normal human urine positively correlated to coffee consumption and influenced by the dietary intake of diverse types of food. (PMID:16870009) [HMDB]. Caffeic acid is found in many foods, some of which are cardoon, coriander, common persimmon, and irish moss.
D020011 - Protective Agents > D000975 - Antioxidants
Annotation level-2
CONFIDENCE standard compound; INTERNAL_ID 167
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.412
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.403
Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).
Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).
Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).

同义名列表

6 个代谢物同义名

Caffeic Acid; trans-Caffeate; 3,4-dihydroxy cinnamic acid; 3,4-dihydroxycinnamic acid; Caffeate; Caffeate



数据库引用编号

79 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1249 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 14 ACE, AKT1, ALOX5, ANG, ARG1, BCL2, CASP3, GPX1, NOS2, PIK3CA, TP53, TYR, VEGFA, XDH
Peripheral membrane protein 2 ALOX5, CYP1B1
Endoplasmic reticulum membrane 2 BCL2, CYP1B1
Nucleus 8 AKT1, ANG, ARG1, BCL2, CASP3, NOS2, TP53, VEGFA
cytosol 12 AKT1, ALOX5, ANG, ARG1, BCL2, CASP3, GPX1, LIPE, NOS2, PIK3CA, TP53, XDH
centrosome 1 TP53
nucleoplasm 5 AKT1, ALOX5, CASP3, NOS2, TP53
Cell membrane 4 ACE, AKT1, LIPE, MGAM
lamellipodium 2 AKT1, PIK3CA
Cytoplasmic granule 1 ARG1
cell cortex 1 AKT1
cell surface 1 VEGFA
glutamatergic synapse 2 AKT1, CASP3
Golgi apparatus 1 VEGFA
growth cone 1 ANG
neuronal cell body 2 ANG, CASP3
postsynapse 1 AKT1
Cytoplasm, cytosol 3 ALOX5, LIPE, NOS2
Lysosome 2 ACE, TYR
endosome 1 ACE
plasma membrane 6 ACE, AKT1, BCHE, MGAM, NOS2, PIK3CA
Membrane 8 ACE, AKT1, BCL2, CYP1B1, LIPE, MGAM, TP53, VEGFA
apical plasma membrane 1 MGAM
caveola 1 LIPE
extracellular exosome 2 ACE, MGAM
endoplasmic reticulum 3 BCL2, TP53, VEGFA
extracellular space 9 ACE, ALOX5, ANG, ARG1, BCHE, CXCL8, IL10, VEGFA, XDH
perinuclear region of cytoplasm 4 ALOX5, NOS2, PIK3CA, TYR
adherens junction 1 VEGFA
intercalated disc 1 PIK3CA
mitochondrion 4 BCL2, CYP1B1, GPX1, TP53
protein-containing complex 3 AKT1, BCL2, TP53
intracellular membrane-bounded organelle 2 CYP1B1, TYR
Microsome membrane 1 CYP1B1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 2 ACE, TYR
Secreted 7 ACE, ANG, BCHE, CXCL8, IL10, MGAM, VEGFA
extracellular region 9 ACE, ALOX5, ANG, ARG1, BCHE, CXCL8, IL10, MGAM, VEGFA
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 2 BCL2, MGAM
mitochondrial outer membrane 1 BCL2
Mitochondrion matrix 1 TP53
mitochondrial matrix 2 GPX1, TP53
transcription regulator complex 1 TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
Nucleus membrane 2 ALOX5, BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 2 ALOX5, BCL2
external side of plasma membrane 1 ACE
Secreted, extracellular space, extracellular matrix 1 VEGFA
actin cytoskeleton 1 ANG
microtubule cytoskeleton 1 AKT1
nucleolus 2 ANG, TP53
Melanosome membrane 1 TYR
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
cell-cell junction 1 AKT1
Golgi-associated vesicle 1 TYR
vesicle 1 AKT1
Cytoplasm, perinuclear region 2 ALOX5, NOS2
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 TP53
spindle 1 AKT1
extracellular matrix 1 VEGFA
Peroxisome 2 NOS2, XDH
basement membrane 1 ANG
sarcoplasmic reticulum 1 XDH
peroxisomal matrix 1 NOS2
Nucleus, PML body 1 TP53
PML body 1 TP53
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
secretory granule 1 VEGFA
ciliary basal body 1 AKT1
chromatin 1 TP53
Chromosome 1 ANG
brush border membrane 1 ACE
Nucleus, nucleolus 1 ANG
blood microparticle 1 BCHE
sperm midpiece 1 ACE
site of double-strand break 1 TP53
nuclear envelope 1 ALOX5
Nucleus envelope 1 ALOX5
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
tertiary granule membrane 1 MGAM
Melanosome 1 TYR
Cytoplasm, Stress granule 1 ANG
cytoplasmic stress granule 1 ANG
germ cell nucleus 1 TP53
replication fork 1 TP53
myelin sheath 1 BCL2
basal plasma membrane 1 ACE
ficolin-1-rich granule lumen 1 ALOX5
secretory granule lumen 1 ALOX5
endoplasmic reticulum lumen 1 BCHE
nuclear matrix 2 ALOX5, TP53
transcription repressor complex 1 TP53
platelet alpha granule lumen 1 VEGFA
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
specific granule lumen 1 ARG1
endocytic vesicle 1 ANG
azurophil granule lumen 1 ARG1
Nucleus matrix 1 ALOX5
nuclear envelope lumen 2 ALOX5, BCHE
[Isoform 1]: Nucleus 1 TP53
ficolin-1-rich granule membrane 1 MGAM
death-inducing signaling complex 1 CASP3
cortical cytoskeleton 1 NOS2
angiogenin-PRI complex 1 ANG
Nucleus intermembrane space 1 ALOX5
BAD-BCL-2 complex 1 BCL2
[Angiotensin-converting enzyme, soluble form]: Secreted 1 ACE
[Isoform Testis-specific]: Cell membrane 1 ACE
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA


文献列表

  • Fan-Zhi Bu, Su-Su Meng, Ling-Yang Wang, Zhi-Yong Wu, Yan-Tuan Li. Bifonazole caffeate: The first molecular salt of bifonazole with enhanced biopharmaceutical property based on experiments and quantum chemistry research. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2024 Sep; 317(?):124403. doi: 10.1016/j.saa.2024.124403. [PMID: 38710138]
  • Jinyue He, Zhuoen He, Hao Wang, Chi Zhang, Tingting Pei, Shihua Yan, Yangtian Yan, Fujing Wang, Yuchi Chen, Ningning Yuan, Mingqing Wang, Wei Xiao. Caffeic acid alleviates skeletal muscle atrophy in 5/6 nephrectomy rats through the TLR4/MYD88/NF-kB pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 May; 174(?):116556. doi: 10.1016/j.biopha.2024.116556. [PMID: 38636398]
  • Wei Fang, Mingyu Jin, Wentao Qi, Chunli Kong, Ge Song, Wenting Peng, Yong Wang. Caffeic acid combined with arabinoxylan or β-glucan attenuates diet-induced obesity in mice via modulation of gut microbiota and metabolites. International journal of biological macromolecules. 2024 May; 268(Pt 2):131683. doi: 10.1016/j.ijbiomac.2024.131683. [PMID: 38649076]
  • Jiahui Yu, Jingchen Xie, Miao Sun, Suhui Xiong, Chunfang Xu, Zhimin Zhang, Minjie Li, Chun Li, Limei Lin. Plant-Derived Caffeic Acid and Its Derivatives: An Overview of Their NMR Data and Biosynthetic Pathways. Molecules (Basel, Switzerland). 2024 Apr; 29(7):. doi: 10.3390/molecules29071625. [PMID: 38611904]
  • Maciej Jakobina, Jacek Łyczko, Antoni Szumny, Renata Galek. The influence of cultivation conditions on the formation of psychoactive salvinorin A, salvinorin B, rosmarinic acid and caffeic acid in Coleus scutellarioides. Scientific reports. 2024 03; 14(1):6693. doi: 10.1038/s41598-024-57399-y. [PMID: 38509159]
  • Jiang-Yan Chen, Sheng Guo, Xiao-Xue Xu, Ya Yang, Yue Zhu, Hong-Jie Kang, Jin-Ao Duan. [Comparison of in vivo pharmacokinetics of twelve constituents in Qihe Fenqing Yin in normal rats and diabetic rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2024 Mar; 49(5):1378-1387. doi: 10.19540/j.cnki.cjcmm.20231210.201. [PMID: 38621986]
  • Yi Xiao, Cao-An Hong, Fang Liu, Dandan Shi, Xinting Zhu, Changyan Yu, Nian Jiang, Sanhua Li, Yun Liu. Caffeic acid activates mitochondrial UPR to resist pathogen infection in Caenorhabditis elegans via the transcription factor ATFS-1. Infection and immunity. 2024 Jan; ?(?):e0049423. doi: 10.1128/iai.00494-23. [PMID: 38294242]
  • Shaweta Sharma, Pawan Kumar Malhotra, Meenakshi Goyal, Vishal Sharma, Amandeep Mittal, Inderjit Singh Yadav, Gulzar Singh Sanghera, Parveen Chhuneja. Characterization of sugarcane mutants developed through gamma irradiations for their lignin content and caffeic acid-O-methyl transferase (COMT) gene mutations. International journal of radiation biology. 2024; 100(4):619-626. doi: 10.1080/09553002.2023.2295962. [PMID: 38166242]
  • Mei-Ling Chen, Hui-Yu Jiang, Jun Zeng, Ling Huang, Chuan-Zhu Lv. Caffeic acid attenuates tissue damage and inflammatory response in Klebsiella pneumonia by modulating AhR-Src-STAT3-IL-10 signaling pathway. Environmental toxicology. 2023 Dec; ?(?):. doi: 10.1002/tox.24086. [PMID: 38148636]
  • Marika Mróz, Barbara Kusznierewicz. Phytochemical screening and biological evaluation of Greek sage (Salvia fruticosa Mill.) extracts. Scientific reports. 2023 12; 13(1):22309. doi: 10.1038/s41598-023-49695-w. [PMID: 38102229]
  • Erik K R Hanko, João Correia, Caio S Souza, Alison Green, Jakub Chromy, Ruth Stoney, Cunyu Yan, Eriko Takano, Diana Lousa, Cláudio M Soares, Rainer Breitling. Microbial production of the plant flavanone hesperetin from caffeic acid. BMC research notes. 2023 Nov; 16(1):343. doi: 10.1186/s13104-023-06620-8. [PMID: 37978406]
  • Xiuli Li, Lumin Yang, Meng Hao, Tingting Song, Yufeng He, Mingchuan Yang, Jinsong Zhang. Chlorogenic acid as an indispensible partner of caffeic acid in coffee via selective regulation of prooxidative actions of caffeic acid. Food research international (Ottawa, Ont.). 2023 Nov; 173(Pt 2):113482. doi: 10.1016/j.foodres.2023.113482. [PMID: 37803805]
  • Jin-Chao Xiao, Ling Wang, Li Zhang, Ming-Yan Chi, Yong Huang, Zi-Peng Gong, Lin Zheng, Feng He. [Determination of plasma protein binding rate of Shuganning Injection using equilibrium dialysis and UPLC-MS/MS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Nov; 48(22):6183-6190. doi: 10.19540/j.cnki.cjcmm.20230618.204. [PMID: 38114225]
  • Enade P Istyastono, Nunung Yuniarti, Vivitri D Prasasty, Sudi Mungkasi, Stephanus S W Waskitha, Michael R S Yanuar, Florentinus D O Riswanto. Caffeic Acid in Spent Coffee Grounds as a Dual Inhibitor for MMP-9 and DPP-4 Enzymes. Molecules (Basel, Switzerland). 2023 Oct; 28(20):. doi: 10.3390/molecules28207182. [PMID: 37894660]
  • Xin-Nan Li, Nian-Ying Shang, Yu-Ying Kang, Ning Sheng, Jia-Qi Lan, Jing-Shu Tang, Lei Wu, Jin-Lan Zhang, Ying Peng. Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway. Acta pharmacologica Sinica. 2023 Oct; ?(?):. doi: 10.1038/s41401-023-01177-5. [PMID: 37833536]
  • Yi-Fen Chiang, I-Cheng Lin, Ko-Chieh Huang, Hsin-Yuan Chen, Mohamed Ali, Yun-Ju Huang, Shih-Min Hsia. Caffeic acid's role in mitigating polycystic ovary syndrome by countering apoptosis and ER stress triggered by oxidative stress. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Oct; 166(?):115327. doi: 10.1016/j.biopha.2023.115327. [PMID: 37619480]
  • Aytül Uzun Akgeyik, Emine Yalçın, Kültiğin Çavuşoğlu. Phytochemical fingerprint and biological activity of raw and heat-treated Ornithogalum umbellatum. Scientific reports. 2023 08; 13(1):13733. doi: 10.1038/s41598-023-41057-w. [PMID: 37612432]
  • Aleksandra Petrović, Višnja Madić, Gordana Stojanović, Ivana Zlatanović, Bojan Zlatković, Perica Vasiljević, Ljubiša Đorđević. Antidiabetic effects of polyherbal mixture made of Centaurium erythraea, Cichorium intybus and Potentilla erecta. Journal of ethnopharmacology. 2023 Aug; ?(?):117032. doi: 10.1016/j.jep.2023.117032. [PMID: 37582477]
  • Phuong Hong Le, Linh Thuy Thi Ho, Dao Hong Thi Le, Viet Nguyen. Purification of Coffee Polyphenols Extracted from Coffee Pulps (Coffee arabica L.) Using Aqueous Two-Phase System. Molecules (Basel, Switzerland). 2023 Aug; 28(15):. doi: 10.3390/molecules28155922. [PMID: 37570892]
  • Farkhondeh Safari, Hamid Hassanpour, Ahmad Alijanpour. Evaluation of hackberry (Celtis australis L.) fruits as sources of bioactive compounds. Scientific reports. 2023 07; 13(1):12233. doi: 10.1038/s41598-023-39421-x. [PMID: 37507445]
  • Xiao-Jing Lin, Zheng-Shi-Yu Lai, Qun Luo, Mei Kong, Min-Jian Liang, Hong Wu, Mei Bai. Correlation between Polyphenol Contents and Antioxidant Activities in Different Echinacea Purpurea Varieties. Current medical science. 2023 Jul; ?(?):. doi: 10.1007/s11596-022-2647-8. [PMID: 37480412]
  • Yueting Yu, Jia Wang, Qingze Liu, Fangyong Wei, Xuejun Xie, Mei Zhang. Integrated serum pharmacochemistry and serum pharmacology to investigate the active components and mechanism of Bushen Huoxue Prescription in the treatment of diabetic retinopathy. Journal of pharmaceutical and biomedical analysis. 2023 Jul; 235(?):115586. doi: 10.1016/j.jpba.2023.115586. [PMID: 37494766]
  • Chunliu Wang, Jie Zhou, Shixiang Wang, Yang Liu, Kaihua Long, Tingting Sun, Wenbing Zhi, Yang Yang, Hong Zhang, Ye Zhao, Xiaopu Zheng, Xiaohui Zheng, Ye Li, Pu Jia. Guanxining injection alleviates fibrosis in heart failure mice and regulates SLC7A11/GPX4 axis. Journal of ethnopharmacology. 2023 Jun; 310(?):116367. doi: 10.1016/j.jep.2023.116367. [PMID: 36914037]
  • Flávia Almeida Santos, Ana Flávia Seraine Custódio Viana, Paulo Iury Gomes Nunes, Benedito Yago Machado Portela, Ana Paula Negreiros Nunes Alves, Daniel de Araújo Viana, Kaline Rodrigues Carvalho, Rita de Cássia Alves Pereira, Paulo Riceli Vasconcelos Ribeiro, Elenilson Godoy Alves-Filho, Edy Sousa de Brito, Edilberto Rocha Silveira, Kirley Marques Canuto. UPLC-QTOF-MS/MS-based metabolomic approach and gastroprotective effect of two chemotypes of Egletes viscosa (L.) less. against ethanol-induced gastric ulcer in mice. Journal of ethnopharmacology. 2023 Jun; 309(?):116348. doi: 10.1016/j.jep.2023.116348. [PMID: 36894109]
  • Rupesh Banerjee, Barun Das Gupta, Amit Kar, Pardeep Kumar Bhardwaj, Nanaocha Sharma, Pallab Kanti Haldar, Rajib Bandyopadhyay, Pulok Kumar Mukherjee. Quality evaluation of different black rice varieties of northeastern region of India. Phytochemical analysis : PCA. 2023 May; ?(?):. doi: 10.1002/pca.3230. [PMID: 37192739]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Peng Zheng, Jieyu Ge, Jiayi Ji, Jingling Zhong, Hongyu Chen, Daren Luo, Wei Li, Bo Bi, Yongjun Ma, Wanghui Tong, Leiqin Han, Siqi Ma, Yuqi Zhang, Jianping Wu, Yanqiu Zhao, Ronghui Pan, Pengxiang Fan, Mengzhu Lu, Hao Du. Metabolic engineering and mechanical investigation of enhanced plant autoluminescence. Plant biotechnology journal. 2023 May; ?(?):. doi: 10.1111/pbi.14068. [PMID: 37155328]
  • Godfrey R Matowane, Samson S Mashele, Tshepiso J Makhafola, Chika I Chukwuma. The ameliorative effect of zinc acetate with caffeic acid in the animal model of type 2 diabetes. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Apr; 163(?):114779. doi: 10.1016/j.biopha.2023.114779. [PMID: 37119739]
  • Lin Lin, Shuangxi Peng, Xiaochen Chen, Changzhu Li, Haiying Cui. Silica nanoparticles loaded with caffeic acid to optimize the performance of cassava starch/sodium carboxymethyl cellulose film for meat packaging. International journal of biological macromolecules. 2023 Apr; 241(?):124591. doi: 10.1016/j.ijbiomac.2023.124591. [PMID: 37116847]
  • Aline Yammine, Lizette Auezova, Gérard Lizard, Hélène Greige-Gerges. Activity of Na+/K+- and Ca2+-ATPases in human erythrocyte membranes: Protocol improvement, relation to cholesterol content, and effects of polyphenols. Biochimie. 2023 Apr; 212(?):95-105. doi: 10.1016/j.biochi.2023.04.010. [PMID: 37098369]
  • Joo Young Kim, Keun Ho Cho, Shea A Keene, Thomas A Colquhoun. Altered profile of floral volatiles and lignin content by down-regulation of Caffeoyl Shikimate Esterase in Petunia. BMC plant biology. 2023 Apr; 23(1):210. doi: 10.1186/s12870-023-04203-0. [PMID: 37085749]
  • Visessakseth So, Philip Poul, Sokunvary Oeung, Pich Srey, Kimchhay Mao, Huykhim Ung, Poliny Eng, Mengkhim Heim, Marnick Srun, Chantha Chheng, Sin Chea, Tarapong Srisongkram, Natthida Weerapreeyakul. Bioactive Compounds, Antioxidant Activities, and HPLC Analysis of Nine Edible Sprouts in Cambodia. Molecules (Basel, Switzerland). 2023 Mar; 28(6):. doi: 10.3390/molecules28062874. [PMID: 36985845]
  • Stéphanie Andrade, Maria C Pereira, Joana A Loureiro. Caffeic acid loaded into engineered lipid nanoparticles for Alzheimer's disease therapy. Colloids and surfaces. B, Biointerfaces. 2023 Mar; 225(?):113270. doi: 10.1016/j.colsurfb.2023.113270. [PMID: 36996633]
  • Marielena Vogel Saivish, Carolina Colombelli Pacca, Vivaldo Gomes da Costa, Gabriela de Lima Menezes, Roosevelt Alves da Silva, Liliane Nebo, Gislaine Celestino Dutra da Silva, Bruno Henrique Gonçalves de Aguiar Milhim, Igor da Silva Teixeira, Tiago Henrique, Natalia Franco Bueno Mistrão, Victor Miranda Hernandes, Nathalia Zini, Ana Carolina de Carvalho, Marina Alves Fontoura, Paula Rahal, Lívia Sacchetto, Rafael Elias Marques, Maurício Lacerda Nogueira. Caffeic Acid Has Antiviral Activity against Ilhéus Virus In Vitro. Viruses. 2023 Feb; 15(2):. doi: 10.3390/v15020494. [PMID: 36851709]
  • Rui Sun, Tao Wu, Shu Xing, Sheng Wei, John K Bielicki, Xuefang Pan, Mingyang Zhou, Jianbin Chen. Caffeic acid protects against atherosclerotic lesions and cognitive decline in ApoE-/- mice. Journal of pharmacological sciences. 2023 Feb; 151(2):110-118. doi: 10.1016/j.jphs.2022.12.006. [PMID: 36707176]
  • Alejandra Arancibia-Díaz, Carolina Astudillo-Castro, Claudia Altamirano, Carmen Soto-Maldonado, Mauricio Vergara-Castro, Andrés Córdova, María Elvira Zúñiga-Hansen. Development of solid-state fermentation process of spent coffee grounds for the differentiated obtaining of chlorogenic, quinic, and caffeic acids. Journal of the science of food and agriculture. 2023 Jan; 103(1):420-427. doi: 10.1002/jsfa.12156. [PMID: 36373791]
  • Junying Ma, Xiaoyan Li, Maolin He, Yanwen Li, Wei Lu, Mengyao Li, Bo Sun, Yangxia Zheng. A Joint Transcriptomic and Metabolomic Analysis Reveals the Regulation of Shading on Lignin Biosynthesis in Asparagus. International journal of molecular sciences. 2023 Jan; 24(2):. doi: 10.3390/ijms24021539. [PMID: 36675053]
  • Luka Šturm, Ilja Gasan Osojnik Črnivec, Iztok Prislan, Nataša Poklar Ulrih. Comparing the Effects of Encapsulated and Non-Encapsulated Propolis Extracts on Model Lipid Membranes and Lactic Bacteria, with Emphasis on the Synergistic Effects of Its Various Compounds. Molecules (Basel, Switzerland). 2023 Jan; 28(2):. doi: 10.3390/molecules28020712. [PMID: 36677770]
  • Ling-Ling Zheng, Mei-Lan Chen, Li-Ping Kang, Ying-Li Wang, Xiu-Teng Zhou. [Effect of Rhizophagus intraradices on growth of Salvia miltiorrhiza]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Jan; 48(2):349-355. doi: 10.19540/j.cnki.cjcmm.20221017.101. [PMID: 36725224]
  • Rongrong Xing, Tingyu Xue, Peng Ye, Li Yang, Runqin Wang, Xuan Chen, Shuang Hu. pH-Responsive epitope-imprinted magnetic nanoparticles for selective separation and extraction of chlorogenic acid and caffeic acid in traditional Chinese medicines. Analytical methods : advancing methods and applications. 2022 12; 14(47):4931-4937. doi: 10.1039/d2ay01667b. [PMID: 36441178]
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