Rutin (BioDeep_00000332518)

Main id: BioDeep_00000000225

 

natural product PANOMIX_OTCML-2023 PANOMIX-Anthocyanidin BioNovoGene_Lab2019


代谢物信息卡片


2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-2-tetrahydropyranyl]oxymethyl]-2-tetrahydropyranyl]oxy]-4-chromenone

化学式: C27H30O16 (610.1534)
中文名称: 芸香苷水合物, 芦丁
谱图信息: 最多检出来源 Homo sapiens(otcml) 14.47%

分子结构信息

SMILES: c(c5)(O)cc(c(c52)C(C(O[C@H](O3)[C@@H]([C@H]([C@@H]([C@H]3CO[C@@H]([C@@H]4O)O[C@H]([C@@H]([C@H]4O)O)C)O)O)O)=C(O2)c(c1)ccc(O)c1O)=O)O
InChI: InChI=1S/C27H30O16/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9/h2-6,8,15,17-18,20-23,26-33,35-38H,7H2,1H3/t8-,15+,17-,18 ,20 ,21-,22 ,23 ,26 ,27-/m1/s1

描述信息

C - Cardiovascular system > C05 - Vasoprotectives > C05C - Capillary stabilizing agents > C05CA - Bioflavonoids
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2352
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.724
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.728
Acquisition and generation of the data is financially supported by the Max-Planck-Society
IPB_RECORD: 1921; CONFIDENCE confident structure
Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress[1][2][3].
Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress[1][2][3].

同义名列表

72 个代谢物同义名

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-2-tetrahydropyranyl]oxymethyl]-2-tetrahydropyranyl]oxy]-4-chromenone; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxymethyl]tetrahydropyran-2-yl]oxy-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxymethyl]tetrahydropyran-2-yl]oxy-chromone; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxymethyl]oxan-2-yl]oxy-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one; 4H-1-Benzopyran-4-one, 3-[[6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]-oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-; 4H-1-Benzopyran-4-one, 3-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-; 3-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one; 3-[[6-O-(6-Deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one; 2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-4-OXO-4H-CHROMEN-3-YL 6-O-(6-DEOXY-ALPHA-L-MANNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-mannopyranoside; Glucopyranoside, quercetin-3 6-O-(6-deoxy-alpha-L-mannopyranosyl)-, beta-D-; Quercetin, 3-(6-0-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside); 3,3,4,5,5,7-Hexahydroxyflavone (6-O-alpha-L-rhamnosyl-beta-D-glucoside); Quercetin, 3-(6-O-alpha-L-rhamnopyranosyl-beta-D-glucopyranoside); Glucopyranoside, quercetin-3 6-O-alpha-L-rhamnopyranosyl-, beta-D; 3-Rhamnoglucoside of 3,3,4,5,7-pentahydroxyflavone; 5-18-05-00519 (Beilstein Handbook Reference); Quercetin 3-O-beta-D-rutinoside; Rutinoside, quercetin-3, beta-; Quercetin-3beta-rutinoside; Quercetin rhamnoglucosine; 345,7-tetOH-Flavone-3-rut; Quercetin-3-rutinoside; Rutosido [INN-Spanish]; Rutosidum [INN-Latin]; EINECS 205-814-1; NCGC00160628-01; Sophorin (VAN); DivK1c_000644; MEGxp0_000068; ZINC04096846; ACon1_000075; KBio1_000644; Bioflavonoid; NINDS_000644; SMR000112560; MLS000759398; Neoisorutin; 164535-43-7; AIDS-001409; IDI1_000644; CHEBI:28527; 115888-40-9; 158560-09-9; 146525-66-8; BRN 0075455; Rutin [JAN]; Phytomelin; CCRIS 7564; 18449-50-8; 48197-72-4; AIDS001409; 56764-99-9; AI3-19098; 1416-01-9; Rutosidum; USAF CF-5; NSC 9220; Rutosido; rutoside; 153-18-4; Rutinum; C05625; Rutine; Rutin; RUT; 3-O-Rutinosyl-ruercetin; Quercetin 3-O-rutinoside; Quercetin 3-O-rhamnose-7-O-glucose; Yunxianggan; Rutin



数据库引用编号

88 个数据库交叉引用编号

分类词条

1898 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 14 ABCB1, ADIG, AKR1B1, AKT1, ALB, FASN, HPGDS, NOS3, PIK3CA, PPARG, PRKAA2, TP53, TYR, XDH
Nucleus 8 ADIG, AKT1, ALB, JUN, NOS3, PPARG, PRKAA2, TP53
cytosol 13 AKR1B1, AKT1, ALB, FASN, HPGDS, IL1B, LIPE, NOS3, PIK3CA, PPARG, PRKAA2, TP53, XDH
dendrite 1 PRKAA2
centrosome 2 ALB, TP53
nucleoplasm 8 AKR1B1, AKT1, HPGDS, JUN, NOS3, PPARG, PRKAA2, TP53
RNA polymerase II transcription regulator complex 2 JUN, PPARG
Cell membrane 4 ABCB1, AKT1, LIPE, MGAM
lamellipodium 2 AKT1, PIK3CA
Multi-pass membrane protein 1 ABCB1
cell cortex 1 AKT1
cell surface 1 ABCB1
glutamatergic synapse 1 AKT1
Golgi apparatus 4 ALB, FASN, NOS3, PRKAA2
Golgi membrane 1 NOS3
neuronal cell body 1 PRKAA2
postsynapse 1 AKT1
Cytoplasm, cytosol 2 IL1B, LIPE
Lysosome 2 IL1B, TYR
plasma membrane 7 ABCB1, AKT1, BCHE, FASN, MGAM, NOS3, PIK3CA
Membrane 8 ABCB1, ADIG, AKT1, FASN, LIPE, MGAM, PRKAA2, TP53
apical plasma membrane 2 ABCB1, MGAM
axon 1 PRKAA2
caveola 2 LIPE, NOS3
extracellular exosome 5 ABCB1, AKR1B1, ALB, FASN, MGAM
endoplasmic reticulum 2 ALB, TP53
extracellular space 6 AKR1B1, ALB, BCHE, CXCL8, IL1B, XDH
perinuclear region of cytoplasm 4 NOS3, PIK3CA, PPARG, TYR
intercalated disc 1 PIK3CA
mitochondrion 2 AKR1B1, TP53
protein-containing complex 3 AKT1, ALB, TP53
intracellular membrane-bounded organelle 3 HPGDS, PPARG, TYR
Single-pass type I membrane protein 1 TYR
Secreted 6 ADIG, ALB, BCHE, CXCL8, IL1B, MGAM
extracellular region 6 ADIG, ALB, BCHE, CXCL8, IL1B, MGAM
Single-pass membrane protein 2 ADIG, MGAM
Mitochondrion matrix 1 TP53
mitochondrial matrix 1 TP53
anchoring junction 1 ALB
transcription regulator complex 2 JUN, TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
microtubule cytoskeleton 1 AKT1
nucleolus 1 TP53
Melanosome membrane 1 TYR
Cytoplasm, P-body 1 NOS3
P-body 1 NOS3
cell-cell junction 1 AKT1
Golgi-associated vesicle 1 TYR
vesicle 1 AKT1
Apical cell membrane 1 ABCB1
Cytoplasm, cytoskeleton 1 TP53
spindle 1 AKT1
Peroxisome 1 XDH
sarcoplasmic reticulum 1 XDH
Nucleus, PML body 1 TP53
PML body 1 TP53
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
secretory granule 1 IL1B
nuclear speck 1 PRKAA2
receptor complex 1 PPARG
ciliary basal body 2 AKT1, ALB
chromatin 3 JUN, PPARG, TP53
cytoskeleton 1 NOS3
centriole 1 ALB
spindle pole 1 ALB
nuclear chromosome 1 JUN
blood microparticle 2 ALB, BCHE
site of double-strand break 1 TP53
Lipid droplet 2 ADIG, LIPE
Membrane, caveola 1 LIPE
tertiary granule membrane 1 MGAM
Melanosome 2 FASN, TYR
Cytoplasm, Stress granule 1 NOS3
cytoplasmic stress granule 2 NOS3, PRKAA2
euchromatin 1 JUN
germ cell nucleus 1 TP53
replication fork 1 TP53
endoplasmic reticulum lumen 2 ALB, BCHE
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
platelet alpha granule lumen 1 ALB
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
endocytic vesicle membrane 1 NOS3
Secreted, extracellular exosome 1 IL1B
nuclear envelope lumen 1 BCHE
[Isoform 1]: Nucleus 1 TP53
ficolin-1-rich granule membrane 1 MGAM
external side of apical plasma membrane 1 ABCB1
nucleotide-activated protein kinase complex 1 PRKAA2
transcription factor AP-1 complex 1 JUN
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
glycogen granule 1 FASN
ciliary transition fiber 1 ALB


文献列表

  • Libo Wang, Yilin Huang, Yanjuan Ren, Haoran Wang, Yue Ding, Guangyue Ren, Tongtong Wang, Zaigui Li, Ju Qiu. Effect of ethanol addition on the physicochemical, structural and in vitro digestive properties of Tartary buckwheat starch-quercetin/rutin complexes. Food chemistry. 2024 Sep; 451(?):139350. doi: 10.1016/j.foodchem.2024.139350. [PMID: 38663246]
  • Yinsheng Wu, Yong Wang, Fengyan Chen, Bingzhang Wang. Loading rutin on surfaces by the layer-by-layer assembly technique to improve the oxidation resistance and osteogenesis of titanium implants in osteoporotic rats. Biomedical materials (Bristol, England). 2024 May; 19(4):. doi: 10.1088/1748-605x/ad4aa8. [PMID: 38740037]
  • Kseniya Bushmeleva, Alexandra Vyshtakalyuk, Dmitriy Terenzhev, Timur Belov, Evgeniy Nikitin, Vladimir Zobov. Effect of Flavonols of Aronia melanocarpa Fruits on Morphofunctional State of Immunocompetent Organs of Rats under Cyclophosphamide-Induced Immunosuppression. Biomolecules. 2024 May; 14(5):. doi: 10.3390/biom14050578. [PMID: 38785985]
  • Dili Lai, Kaixuan Zhang, Yuqi He, Yu Fan, Wei Li, Yaliang Shi, Yuanfen Gao, Xu Huang, Jiayue He, Hui Zhao, Xiang Lu, Yawen Xiao, Jianping Cheng, Jingjun Ruan, Milen I Georgiev, Alisdair R Fernie, Meiliang Zhou. Multi-omics identification of a key glycosyl hydrolase gene FtGH1 involved in rutin hydrolysis in Tartary buckwheat (Fagopyrum tataricum). Plant biotechnology journal. 2024 May; 22(5):1206-1223. doi: 10.1111/pbi.14259. [PMID: 38062934]
  • Tongtong Yi, Wei Zhang, Ying Hua, Xingpan Xin, Zhenyu Wu, Ying Li, Chengping Wen, Yongsheng Fan, Jinjun Ji, Li Xu. Rutin alleviates lupus nephritis by inhibiting T cell oxidative stress through PPARγ. Chemico-biological interactions. 2024 May; 394(?):110972. doi: 10.1016/j.cbi.2024.110972. [PMID: 38555047]
  • Yadi Liu, Zhongyan Sun, Ruixue Dong, Peiyu Liu, Xi Zhang, Yiran Li, Xiaoshan Lai, Hio-Fai Cheong, Yuwei Wu, Yilin Wang, Hua Zhou, Dingkun Gui, Youhua Xu. Rutin ameliorated lipid metabolism dysfunction of diabetic NAFLD via AMPK/SREBP1 pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Apr; 126(?):155437. doi: 10.1016/j.phymed.2024.155437. [PMID: 38394735]
  • Youwei Du, Huiya Ma, Yuanyuan Liu, Rui Gong, Yu Lan, Jianhua Zhao, Guangli Liu, Yiming Lu, Shuanghong Wang, Hongchen Jia, Na Li, Rong Zhang, Junru Wang, Guangyu Sun. Major quality regulation network of flavonoid synthesis governing the bioactivity of black wolfberry. The New phytologist. 2024 Apr; 242(2):558-575. doi: 10.1111/nph.19602. [PMID: 38396374]
  • Yanmei Shi, Kai Hu, Lin Mei, Liqin Chao, Mingxia Wu, Zhihong Chen, Xiangxiang Wu, Jingyi Qiao, Pingsheng Zhu, Mingsan Miao, Sisen Zhang. Platforms of graphene/MXene heterostructure for electrochemical monitoring of rutin in drug and Tartary buckwheat tea. Talanta. 2024 Apr; 270(?):125548. doi: 10.1016/j.talanta.2023.125548. [PMID: 38104427]
  • M Mesud Hurkul, Seyda Yayla, Ahmet Cetinkaya, S Irem Kaya, Lokman Uzun, Sibel A Ozkan. A novel electrochemical sensor based on a molecularly imprinted polymer for highly selective and sensitive determination of rutin from herbal supplements and plant extracts. Analytical methods : advancing methods and applications. 2024 Mar; 16(10):1480-1488. doi: 10.1039/d3ay02318d. [PMID: 38372557]
  • Magdalena Lasota, Paulina Lechwar, Wirginia Kukula-Koch, Marcin Czop, Karolina Czech, Katarzyna Gaweł-Bęben. Pulp or Peel? Comparative Analysis of the Phytochemical Content and Selected Cosmetic-Related Properties of Annona cherimola L., Diospyros kaki Thumb., Cydonia oblonga Mill. and Fortunella margarita Swingle Pulp and Peel Extracts. Molecules (Basel, Switzerland). 2024 Mar; 29(5):. doi: 10.3390/molecules29051133. [PMID: 38474645]
  • Jayshree V Changade, Harsha Thanvi, Chandrashekhar Raut, Manasi Chavan, Prachi Prasad, Vaibhav S Ladke. In vitro Evaluation of Anti-Cancer Potential of Different Solvent Extracts Derived from Clerodendrum Infortunatum Linn against Cervical Cancer. Asian Pacific journal of cancer prevention : APJCP. 2024 Mar; 25(3):1065-1075. doi: 10.31557/apjcp.2024.25.3.1065. [PMID: 38546089]
  • N D H Cheong, E Mohamed, N Haron, S N Camalxaman, A Abdullah, M I Mohamad Yusof, A R Ishak, S Ab-Rahim, Z Eshak, A R Tualeka. Phytochemical quantification and HPLC analysis of Parkia speciosa pod extract. The Medical journal of Malaysia. 2024 Mar; 79(Suppl 1):34-39. doi: ". [PMID: 38555883]
  • Lei Wang, Jiali Zhao, Yuanbin Mao, Linling Liu, Chenglei Li, Huala Wu, Haixia Zhao, Qi Wu. Tartary buckwheat rutin: Accumulation, metabolic pathways, regulation mechanisms, and biofortification strategies. Plant physiology and biochemistry : PPB. 2024 Mar; 208(?):108503. doi: 10.1016/j.plaphy.2024.108503. [PMID: 38484679]
  • Nattira On-Nom, Sirinapa Thangsiri, Woorawee Inthachat, Piya Temviriyanukul, Yuraporn Sahasakul, Amornrat Aursalung, Chaowanee Chupeerach, Uthaiwan Suttisansanee. Optimized Conditions for the Extraction of Phenolic Compounds from Aeginetia indica L. and Its Potential Biological Applications. Molecules (Basel, Switzerland). 2024 Feb; 29(5):. doi: 10.3390/molecules29051050. [PMID: 38474563]
  • Dennis Soosai, Ravindhran Ramalingam, Elumalai Perumal, Kaviarasan Veeramani, Charles Pancras, Mikhlid H Almutairi, Leo Arockia Raj Savarimuthu, Duraipandiyan Veeramuthu, Stalin Antony. Anticancer effects of rutin from Fagopyrum tataricum (tartary buckwheat) against osteosarcoma cell line. Molecular biology reports. 2024 Feb; 51(1):312. doi: 10.1007/s11033-024-09218-w. [PMID: 38374412]
  • Amel Hamdi, Sara Jaramillo-Carmona, Rocío Rodríguez-Arcos, Ana Jiménez-Araujo, Najoua Karray Bouraoui, Rafael Guillén-Bejarano. Phytochemical Profile and In Vitro Bioactivities of Wild Asparagus stipularis. Molecules (Basel, Switzerland). 2024 Feb; 29(4):. doi: 10.3390/molecules29040817. [PMID: 38398569]
  • Haixia Zhao, Lijiao Wang, Yujie Jia, Jiali Zhao, Chenglei Li, Hui Chen, Huala Wu, Qi Wu. Accumulation of the bitter substance quercetin mediated by the overexpression of a novel seed-specific gene FtRDE2 in Tartary buckwheat. Plant physiology and biochemistry : PPB. 2024 Feb; 207(?):108402. doi: 10.1016/j.plaphy.2024.108402. [PMID: 38310726]
  • Francesco Pettini, Ottavia Spiga, Simone Furini, Fabio Fusi. Electrophysiology, molecular modelling, and functional analysis of the effects of dietary quercetin and flavonoid analogues on Kir6.1 channels in rat stomach fundus smooth muscle. Biochemical pharmacology. 2024 Feb; 220(?):115969. doi: 10.1016/j.bcp.2023.115969. [PMID: 38086489]
  • Haixia Che, Jie Yi, Xiaoting Zhao, Hong Yu, Xianyao Wang, Rui Zhang, Xin Li, Jia Fu, Qian Li. Characterization of PKCα-rutin interactions and their application as a treatment strategy for pulmonary arterial hypertension by inhibiting ferroptosis. Food & function. 2024 Jan; 15(2):779-793. doi: 10.1039/d3fo01306e. [PMID: 38126185]
  • Xinzhuang Ma, Xijuan Ren, Xuemin Zhang, Guangyin Wang, Hui Liu, Li Wang. Rutin ameliorate PFOA induced renal damage by reducing oxidative stress and improving lipid metabolism. The Journal of nutritional biochemistry. 2024 01; 123(?):109501. doi: 10.1016/j.jnutbio.2023.109501. [PMID: 37890710]
  • Devanand Shanmugasundaram, James Martin Roza. Assessment of Anti-Inflammatory and Antioxidant Activities of a Proprietary Preparation of Quercetin-Rutin Blend (SophorOx™) in Exercised Rats. TheScientificWorldJournal. 2024; 2024(?):9063936. doi: 10.1155/2024/9063936. [PMID: 38371227]
  • Fei Sun, Xiang-Qin Wu, Qiong He, Yu-Hua Cao, Jian-Gang Wang, Sheng-Wang Liang, Shu-Mei Wang. [Screening of bioactive components endowing hawthorn with turbidity-eliminating and lipid-lowering functions and development of quality control method of hawthorn]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2024 Jan; 49(1):100-109. doi: 10.19540/j.cnki.cjcmm.20231102.301. [PMID: 38403343]
  • Ângela Barichello, Giovana T Capoani, Flavia M Comachio, Guilherme G Kielb, Gustavo L Colpani, Márcio A Fiori, Max V Gutiérrez, Micheli Zanetti, Vanessa da Silva Corralo, Walter A Roman Junior. Toxicological effects of acute and repeated doses (180 days) of fruits from Malpighia emarginata (acerola) in rodents. Toxicon : official journal of the International Society on Toxinology. 2024 Jan; 237(?):107550. doi: 10.1016/j.toxicon.2023.107550. [PMID: 38061671]
  • Peng Wu, Xiaoyong Wang, Min Yin, Wenjie Zhu, Zheng Chen, Yang Zhang, Ziyu Jiang, Longqing Shi, Qiang Zhu. ULK1 Mediated Autophagy-Promoting Effects of Rutin-Loaded Chitosan Nanoparticles Contribute to the Activation of NF-κB Signaling Besides Inhibiting EMT in Hep3B Hepatoma Cells. International journal of nanomedicine. 2024; 19(?):4465-4493. doi: 10.2147/ijn.s443117. [PMID: 38779103]
  • Zheyuan Ren, Yang Yu, Zhongyao Ji, Huitao Li, Xiaoheng Li, Han Lin, Renshan Ge, Qiqi Zhu. Structure-activity relationship and docking analysis of nature flavonoids as inhibitors of human and rat gonadal 3β-hydroxysteroid dehydrogenases for therapeutic purposes. The Journal of steroid biochemistry and molecular biology. 2023 Dec; 238(?):106450. doi: 10.1016/j.jsbmb.2023.106450. [PMID: 38143010]
  • Mingxia Wang, Xiaoxuan Ma, Chunjie Gao, Yue Luo, Xiaoya Fei, Qi Zheng, Xin Ma, Le Kuai, Bin Li, Ruiping Wang, Jiankun Song. Rutin attenuates inflammation by downregulating AGE-RAGE signaling pathway in psoriasis: Network pharmacology analysis and experimental evidence. International immunopharmacology. 2023 Dec; 125(Pt A):111033. doi: 10.1016/j.intimp.2023.111033. [PMID: 38149569]
  • Zekun Li, Shuang Liang, Huijuan Sun, Cheng Bao, Yuan Li. Antilipogenesis Effect of Rutin-Loaded Liposomes Using a Microneedle Delivery System. ACS applied materials & interfaces. 2023 Nov; 15(47):54294-54303. doi: 10.1021/acsami.3c12795. [PMID: 37972277]
  • Ting Xu, Yangjun Lv, Yuhan Cui, Dongchen Liu, Tao Xu, Baiyi Lu, Xuan Yang. Properties of Dietary Flavone Glycosides, Aglycones, and Metabolites on the Catalysis of Human Endoplasmic Reticulum Uridine Diphosphate Glucuronosyltransferase 2B7 (UGT2B7). Nutrients. 2023 Nov; 15(23):. doi: 10.3390/nu15234941. [PMID: 38068799]
  • Stefania Sut, Stefano Dall'Acqua, Kouadio Ibrahime Sinan, Gokhan Zengin, Abdullah Ibrahim Uba, Ouattara Katinan Etienne, Sharmeen Jugreet, Mohamad Fawzi Mahomoodally. Bioactive agents from Parkia biglobosa (Jacq.) R.Br. ex G. Don bark extracts for health promotion and nutraceutical uses. Journal of the science of food and agriculture. 2023 Nov; ?(?):. doi: 10.1002/jsfa.13170. [PMID: 38009330]
  • Rupali S Prasad, Rupesh V Chikhale, Nitish Rai, Natasha S Akojwar, Raksha A Purohit, Pravesh Sharma, Onkar Kulkarni, Damiki Laloo, Shailendra S Gurav, Prakash R Itankar, Satyendra K Prasad. Rutin from Begonia roxburghii modulates iNOS and Sep A activity in treatment of Shigella flexneri induced diarrhoea in rats: An in vitro, in vivo and computational analysis. Microbial pathogenesis. 2023 Nov; 184(?):106380. doi: 10.1016/j.micpath.2023.106380. [PMID: 37821049]
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