Stigmasterin (BioDeep_00000859665)

Main id: BioDeep_00000000532

 

PANOMIX_OTCML-2023 Chemicals and Drugs


代谢物信息卡片


(3S,8S,9S,10R,13R,14S,17R)-17-[(E,2R,5S)-5-ethyl-6-methyl-hept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

化学式: C29H48O (412.37049579999996)
中文名称: 豆甾醇
谱图信息: 最多检出来源 () 0%

Reviewed

Last reviewed on 2024-08-19.

Cite this Page

Stigmasterin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/stigmasterin (retrieved 2024-11-03) (BioDeep RN: BioDeep_00000859665). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CCC(C=CC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C
InChI: InChI=1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h8-10,19-21,23-27,30H,7,11-18H2,1-6H3/b9-8+/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1

描述信息

C1907 - Drug, Natural Product > C28178 - Phytosterol > C68437 - Unsaturated Phytosterol

同义名列表

41 个代谢物同义名

(3S,8S,9S,10R,13R,14S,17R)-17-[(E,2R,5S)-5-ethyl-6-methyl-hept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; (3S,8S,9S,10R,13R,14S,17R)-17-[(E,1R,4S)-4-ethyl-1,5-dimethyl-hex-2-enyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; (3S,8S,9S,10R,13R,14S,17R)-17-[(E,1R,4S)-4-ethyl-1,5-dimethylhex-2-enyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; (3S,8S,9S,10R,13R,14S,17R)-17-[(E,2R,5S)-5-ethyl-6-methylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5-ethyl-6-methyl-hept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; (3S,8S,9S,10R,13R,14S,17R)-17-[(1R,4S)-4-ethyl-1,5-dimethyl-hex-2-enyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5-ethyl-6-methylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; (3S,8S,9S,10R,13R,14S,17R)-17-[(1R,4S)-4-ethyl-1,5-dimethylhex-2-enyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; Stigmasta-5,22-dien-3-ol, (3beta,22E)- (9CI); (24S)-24-Ethylcholesta-5,22-dien-3beta-ol; Stigmasta-5,22-dien-3-ol, (3beta,22E)-; (3.beta.,22E)-Stigmasta-5,22-dien-3-ol; 24-Ethyl-5,22-cholestadien-3.beta.-ol; .delta.5,22-Stigmastadien-3.beta.-ol; (3beta,22E)-Stigmasta-5,22-dien-3-ol; 24-Ethyl-5,22-cholestadien-3beta-ol; Stigmasta-5,22-dien-3-ol, (3beta)-; Stigmasta-5,22-dien-3beta-ol (8CI); (24S)-5,22-Stigmastadien-3beta-ol; (24S)-Stigmast-5,22-dien-3beta-ol; Delta5,22-Stigmastadien-3beta-ol; Stigmasta-5,22E-dien-3beta-ol; Stigmasta-5,22-dien-3-beta-ol; Stigmasta-5,22-dien-3beta-ol; Stigmasta-5,22-dien-3-ol; Delta5-Stigmasterol; beta-Stigmasterol; EINECS 201-482-7; D5-Stigmasterol; ZINC04096712; LMST01040123; Stigmasterin; Stigmasterol; SMP1_000280; AIDS-002709; AIDS002709; CCRIS 7476; SBB012602; NSC 8095; 83-48-7; C05442



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1215 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ran Huo, Wen-Jing Yang, Yu Liu, Te Liu, Tong Li, Chu-Yu Wang, Bai-Shen Pan, Bei-Li Wang, Wei Guo. Stigmasterol: Remodeling gut microbiota and suppressing tumor growth through Treg and CD8+ T cells in hepatocellular carcinoma. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155225. doi: 10.1016/j.phymed.2023.155225. [PMID: 38678948]
  • Othman Baothman, Ehab M M Ali, Salman Hosawi, Emadeldin Hassan E Konozy, Isam M Abu Zeid, Abrar Ahmad, Hisham N Altayb. Multi-targeted therapeutic potential of stigmasterol from the Euphorbia ammak plant in treating lung and breast cancer. Computational biology and chemistry. 2024 Jun; 110(?):108037. doi: 10.1016/j.compbiolchem.2024.108037. [PMID: 38460436]
  • Sihong Huang, Rong Zhou, Yuyun Yuan, Yiyun Shen. Stigmasterol alleviates airway inflammation in OVA-induced asthmatic mice via inhibiting the TGF-β1/Smad2 and IL-17A signaling pathways. Aging. 2024 Apr; 16(7):6478-6487. doi: 10.18632/aging.205716. [PMID: 38579176]
  • Waimei Si, Zhenni Chen, Jing Bei, Shiquan Chang, Yachun Zheng, Li Gao, Guoping Zhao, Xin Li, Di Zhang. Stigmasterol alleviates neuropathic pain by reducing Schwann cell-macrophage cascade in DRG by modulating IL-34/CSF1R. CNS neuroscience & therapeutics. 2024 04; 30(4):e14657. doi: 10.1111/cns.14657. [PMID: 38572785]
  • Xingzhi Guo, Jing Yu, Rui Wang, Ning Peng, Rui Li. Deciphering the effect of phytosterols on Alzheimer's disease and Parkinson's disease: the mediating role of lipid profiles. Alzheimer's research & therapy. 2024 Mar; 16(1):53. doi: 10.1186/s13195-024-01424-9. [PMID: 38461353]
  • Laura Stanasila, Dieter Lütjohann, Julius Popp, Pedro Marques-Vidal. Association between Serum Phytosterols and Lipid Levels in a Population-Based Study. Nutrients. 2024 Mar; 16(6):. doi: 10.3390/nu16060775. [PMID: 38542686]
  • Xianbin Zhang, Caihong Wang. Exploration on Anti-Depression Mechanism of Baihe Zhimu Decoction Based on Network Pharmacology and Molecular Docking. Studies in health technology and informatics. 2023 Nov; 308(?):417-427. doi: 10.3233/shti230868. [PMID: 38007768]
  • Zhiqiang Zhang, Jiayi Zhou, Ruiqian Guo, Qijun Zhou, Lianzhi Wang, Xingyan Xiang, Sitong Ge, Zhezhu Cui. Network pharmacology to explore the molecular mechanisms of Prunella vulgaris for treating thyroid cancer. Medicine. 2023 Nov; 102(45):e34871. doi: 10.1097/md.0000000000034871. [PMID: 37960775]
  • Waimei Si, Xin Li, Bei Jing, Shiquan Chang, Yachun Zheng, Zhenni Chen, Guoping Zhao, Di Zhang. Stigmasterol regulates microglial M1/M2 polarization via the TLR4/NF-κB pathway to alleviate neuropathic pain. Phytotherapy research : PTR. 2023 Oct; ?(?):. doi: 10.1002/ptr.8039. [PMID: 37871970]
  • Honghua Zhang, Yunting Sun, Yuqing Zou, Cheng Chen, Shuling Wang. Stigmasterol and gastrodin, two major components of banxia-baizhu-tianma decoction, alleviated the excessive phlegm-dampness hypertension by reducing lipid accumulation. Journal of ethnopharmacology. 2023 Sep; 319(Pt 2):117193. doi: 10.1016/j.jep.2023.117193. [PMID: 37726069]
  • Linghui Kong, Xinyi Fan, Limin Guo, Qingqing Jiang, Jianbo Xiao, Daming Fan, Mingfu Wang, Yueliang Zhao. Effects of Stigmasterol on 3-Chloropropane-1,2-diol Fatty Acid Esters and Aldehydes Formation in Heated Soybean Oil. Journal of agricultural and food chemistry. 2023 Aug; ?(?):. doi: 10.1021/acs.jafc.3c01584. [PMID: 37551652]
  • Megha Goswami, Priya, Shalini Jaswal, Ghanshyam Das Gupta, Sant Kumar Verma. A comprehensive update on phytochemistry, analytical aspects, medicinal attributes, specifications and stability of stigmasterol. Steroids. 2023 08; 196(?):109244. doi: 10.1016/j.steroids.2023.109244. [PMID: 37137454]
  • Takeshi Sakaki, Tomoko Koizumi, Yosuke Ikeido, Kouichi Soga, Kazuyuki Wakabayashi, Takayuki Hoson. Increase in steryl glycoside levels and stimulation of lipid raft formation in azuki bean epicotyls under hypergravity conditions. Life sciences in space research. 2023 Aug; 38(?):53-58. doi: 10.1016/j.lssr.2023.05.005. [PMID: 37481308]
  • Ying Wang, Tao Wang, Zhangtie Wang, Yiwen Guo, Ruijie Liu, Ming Chang. Application of SAXS in exploring the effect of edible oils with different unsaturation FAs on bioaccessibility of stigmasterol oleate. Journal of the science of food and agriculture. 2023 Jul; ?(?):. doi: 10.1002/jsfa.12874. [PMID: 37482970]
  • Yan Xin, Xiang Li, Xuan Zhu, Xiaozhuan Lin, Mengliu Luo, Yunjun Xiao, Yongdui Ruan, Honghui Guo. Stigmasterol Protects Against Steatohepatitis Induced by High-Fat and High-Cholesterol Diet in Mice by Enhancing the Alternative Bile Acid Synthesis Pathway. The Journal of nutrition. 2023 Jun; ?(?):. doi: 10.1016/j.tjnut.2023.05.026. [PMID: 37269906]
  • Md Abu Jobaer, Sania Ashrafi, Monira Ahsan, Choudhury Mahmood Hasan, Mohammad Abdur Rashid, Sheikh Nazrul Islam, Mohammad Mehedi Masud. Phytochemical and Biological Investigation of an Indigenous Plant of Bangladesh, Gynura procumbens (Lour.) Merr.: Drug Discovery from Nature. Molecules (Basel, Switzerland). 2023 May; 28(10):. doi: 10.3390/molecules28104186. [PMID: 37241926]
  • Miki Hatada, Ryota Akiyama, Moeko Yamagishi, Kimitsune Ishizaki, Masaharu Mizutani. MpDWF5A-encoded sterol Δ7-reductase is essential for the normal growth and development of Marchantia polymorpha. Plant & cell physiology. 2023 May; ?(?):. doi: 10.1093/pcp/pcad043. [PMID: 37178336]
  • Maria Kasprzak, Magdalena Rudzińska, Wojciech Juzwa, Anna Olejnik. Anti-proliferative potential and oxidative reactivity of thermo-oxidative degradation products of stigmasterol and stigmasteryl esters for human intestinal cells. Scientific reports. 2023 May; 13(1):7093. doi: 10.1038/s41598-023-34335-0. [PMID: 37127788]
  • Witold Gładkowski, Anna Chojnacka, Aleksandra Włoch, Hanna Pruchnik, Aleksandra Grudniewska, Anna Dunal, Anita Dudek, Gabriela Maciejewska, Magdalena Rudzińska. Conjugates of 1,3- and 1,2-Acylglycerols with Stigmasterol: Synthesis, NMR Characterization, and Impact on Lipid Bilayers. ChemPlusChem. 2023 05; 88(5):e202300161. doi: 10.1002/cplu.202300161. [PMID: 36997498]
  • Zi-Yu Chang, Chun-Wei Chen, Ming-Jun Tsai, Chin-Chang Chen, Abdullah Alshetaili, Yu-Tai Hsiao, Jia-You Fang. The elucidation of structure-activity and structure-permeation relationships for the cutaneous delivery of phytosterols to attenuate psoriasiform inflammation. International immunopharmacology. 2023 Apr; 119(?):110202. doi: 10.1016/j.intimp.2023.110202. [PMID: 37075671]
  • Gugulethu Mathews Miya, Ayodeji Oluwabunmi Oriola, Bianca Payne, Marizé Cuyler, Namrita Lall, Adebola Omowunmi Oyedeji. Steroids and Fatty Acid Esters from Cyperus sexangularis Leaf and Their Antioxidant, Anti-Inflammatory and Anti-Elastase Properties. Molecules (Basel, Switzerland). 2023 Apr; 28(8):. doi: 10.3390/molecules28083434. [PMID: 37110668]
  • Ilijana Begcevic Brkovic, Madlen Reinicke, Soroth Chey, Ingo Bechmann, Uta Ceglarek. Characterization of Non-Cholesterol Sterols in Microglia Cell Membranes Using Targeted Mass Spectrometry. Cells. 2023 03; 12(7):. doi: 10.3390/cells12070974. [PMID: 37048046]
  • Fang Zhang, Jiani Wu, Qu Shen, Zhiling Chen, Zukang Qiao. Investigating the mechanism of Tongqiao Huoxue decotion in the treatment of allergic rhinitis based on network pharmacology and molecular docking: A review. Medicine. 2023 Mar; 102(10):e33190. doi: 10.1097/md.0000000000033190. [PMID: 36897696]
  • Nishant Kaushal, Deepika Verma, Anshu Alok, Ashutosh Pandey, Kashmir Singh. Heterologous expression of Chlorophytum borivilianum Squalene epoxidase in tobacco modulates stigmasterol production and alters vegetative and reproductive growth. Plant cell reports. 2023 Mar; ?(?):. doi: 10.1007/s00299-023-03000-1. [PMID: 36894686]
  • Suping Li, Fei Xu, Liang Yu, Qian Yu, Nengwei Yu, Jing Fu. Stigmasterol protects human brain microvessel endothelial cells against ischemia-reperfusion injury through suppressing EPHA2 phosphorylation. Chinese journal of natural medicines. 2023 Feb; 21(2):127-135. doi: 10.1016/s1875-5364(23)60390-5. [PMID: 36871980]
  • Mohammad Sohail Akhtar, S R Mir, Mohammad Amzad Hossain, Mohammed Ali. A novel terpenoid glycoside and other bioactive constituents from the seeds of Cichoriumintybus. Carbohydrate research. 2023 Feb; 524(?):108745. doi: 10.1016/j.carres.2023.108745. [PMID: 36680966]
  • Zenande K S Mcotshana, Lyndy J McGaw, Douglas Kemboi, Gerda Fouche, Ibukun M Famuyide, Rui W M Krause, Xavier Siwe-Noundou, Vuyelwa Jacqueline Tembu. Cytotoxicity and antimicrobial activity of isolated compounds from Monsonia angustifolia and Dodonaea angustifolia. Journal of ethnopharmacology. 2023 Jan; 301(?):115170. doi: 10.1016/j.jep.2022.115170. [PMID: 35358625]
  • Daman Chen, Qiqi Chen, Kaibo Zhao, Yongqi Guo, Yuxin Huang, Zehuan Yuan, Yujia Cai, Sitong Li, Jiarong Xu, Xiaohong Lin. Exploring the mechanism of Xiaoqinglong decoction in the treatment of infantile asthma based on network pharmacology and molecular docking. Medicine. 2023 Jan; 102(2):e32623. doi: 10.1097/md.0000000000032623. [PMID: 36637916]
  • Weibo Dai, Jing Yang, Xin Liu, Quanxi Mei, Weijie Peng, Xianjing Hu. Anti-colorectal cancer of Ardisia gigantifolia Stapf. and targets prediction via network pharmacology and molecular docking study. BMC complementary medicine and therapies. 2023 Jan; 23(1):4. doi: 10.1186/s12906-022-03822-8. [PMID: 36624500]
  • Wendong Xie, Hua Yang, Chun Guo, Rui Xie, Guoliang Yu, Yifu Li. Integrated Network Pharmacology and Experimental Validation Approach to Investigate the Mechanisms of Stigmasterol in the Treatment of Rheumatoid Arthritis. Drug design, development and therapy. 2023; 17(?):691-706. doi: 10.2147/dddt.s387570. [PMID: 36915642]
  • Xiaojing Li, Yueqin Tian, Haidong Wu, Tong Wang. Network Pharmacology and Molecular Docking to Unveil the Mechanism of Shudihuang against Amyotrophic Lateral Sclerosis. Current pharmaceutical design. 2023; 29(19):1535-1545. doi: 10.2174/1381612829666230621105552. [PMID: 37345246]
  • Alessandro Cabianca, Andrea Caroline Ruthes, Katharina Pawlowski, Paul Dahlin. Tomato Sterol 22-desaturase Gene CYP710A11: Its Roles in Meloidogyne incognita Infection and Plant Stigmasterol Alteration. International journal of molecular sciences. 2022 Dec; 23(23):. doi: 10.3390/ijms232315111. [PMID: 36499431]
  • Abdur Rehman, Fatima Noor, Israr Fatima, Muhammad Qasim, Mingzhi Liao. Identification of molecular mechanisms underlying the therapeutic effects of Celosia Cristata on immunoglobulin nephropathy. Computers in biology and medicine. 2022 12; 151(Pt A):106290. doi: 10.1016/j.compbiomed.2022.106290. [PMID: 36379189]
  • Prasobh K Mohan, T P Adarsh Krishna, A Thirumurugan, T Senthil Kumar, B D Ranjitha Kumari. Chemical Profiling and In Vitro Antiurolithiatic Activity of Pleurolobus gangeticus (L.) J. St.- Hil. ex H. Ohashi & K. Ohashi Along with Its Antioxidant and Antibacterial Properties. Applied biochemistry and biotechnology. 2022 Nov; 194(11):5037-5059. doi: 10.1007/s12010-022-04017-0. [PMID: 35687306]
  • Danny Farhat, Fatemeh Rezaei, Milica Ristovski, Yidai Yang, Albert Stancescu, Lucia Dzimkova, Sabrina Samnani, Jean-François Couture, Jyh-Yeuan Lee. Structural Analysis of Cholesterol Binding and Sterol Selectivity by ABCG5/G8. Journal of molecular biology. 2022 10; 434(20):167795. doi: 10.1016/j.jmb.2022.167795. [PMID: 35988751]
  • Shubhadeep Roychoudhury, Dipika Das, Sandipan Das, Niraj Kumar Jha, Mahadeb Pal, Adriana Kolesarova, Kavindra Kumar Kesari, Jogen C Kalita, Petr Slama. Clinical Potential of Himalayan Herb Bergenia ligulata: An Evidence-Based Study. Molecules (Basel, Switzerland). 2022 Oct; 27(20):. doi: 10.3390/molecules27207039. [PMID: 36296631]
  • Marya Aziz, Saeed Ahmad, Umair Khurshid, Irfan Pervaiz, Arslan Hussain Lodhi, Nasrullah Jan, Sameera Khurshid, Muhammad Adeel Arshad, Mohamed M Ibrahim, Gaber A M Mersal, Fahaad S Alenazi, Ahmed Awadh Saleh Alamri, Juwairiya Butt, Hammad Saleem, Zeinhom M El-Bahy. Comprehensive Biological Potential, Phytochemical Profiling Using GC-MS and LC-ESI-MS, and In-Silico Assessment of Strobilanthes glutinosus Nees: An Important Medicinal Plant. Molecules (Basel, Switzerland). 2022 Oct; 27(20):. doi: 10.3390/molecules27206885. [PMID: 36296481]
  • Agata Rogowska, Małgorzata Stpiczyńska, Cezary Pączkowski, Anna Szakiel. The Influence of Exogenous Jasmonic Acid on the Biosynthesis of Steroids and Triterpenoids in Calendula officinalis Plants and Hairy Root Culture. International journal of molecular sciences. 2022 Oct; 23(20):. doi: 10.3390/ijms232012173. [PMID: 36293029]
  • Satyam Sangeet, Arshad Khan, Saurov Mahanta, Nabamita Roy, Sanjib Kumar Das, Yugal Kishore Mohanta, Muthupandian Saravanan, Hui Tag, Pallabi Kalita Hui. Computational analysis of Bacopa monnieri (L.) Wettst. compounds for drug development against Neurodegenerative Disorders. Current computer-aided drug design. 2022 Oct; ?(?):. doi: 10.2174/1573409918666221010103652. [PMID: 36221888]
  • Priya Das, Gouhar Jahan Ashraf, Tania Baishya, Tarun Kumar Dua, Paramita Paul, Gouranga Nandi, Ranabir Sahu. High-performance thin-layer chromatography coupled attenuated total reflectance-Fourier-transform infrared and NMR spectroscopy-based identification of α-amylase inhibitor from the aerial part of Asparagus racemosus Willd. Phytochemical analysis : PCA. 2022 Oct; 33(7):1018-1027. doi: 10.1002/pca.3155. [PMID: 35730071]
  • M Rudzińska, A Olejnik, A Grygier, K Kowalska, D Kmiecik, A Grudniewska, A Chojnacka, W Gładkowski, G Maciejewska, R Przybylski. Thermo-oxidative stability of asymmetric distigmasterol-modified acylglycerols as novel derivatives of plant sterols. Food chemistry. 2022 Oct; 390(?):133150. doi: 10.1016/j.foodchem.2022.133150. [PMID: 35551028]
  • Muhammed Majeed, Furkan Ahmad, Lakshmi Mundkur, Subramoniam Appian. Pharmacology of α-spinasterol, a phytosterol with nutraceutical values: A review. Phytotherapy research : PTR. 2022 Oct; 36(10):3681-3690. doi: 10.1002/ptr.7560. [PMID: 35802356]
  • Blaise Cedric Kamdoum, Ingrid Simo, Steven Collins Njonte Wouamba, Brice Mariscal Tchatat Tali, Bathelemy Ngameni, Ghislain Wabo Fotso, Pantaléon Ambassa, Fekam Boyom Fabrice, Bruno Ndjakou Lenta, Norbert Sewald, Bonaventure Tchaleu Ngadjui. Chemical constituents of two Cameroonian medicinal plants: Sida rhombifolia L. and Sida acuta Burm. f. (Malvaceae) and their antiplasmodial activity. Natural product research. 2022 Oct; 36(20):5311-5318. doi: 10.1080/14786419.2021.1937156. [PMID: 34121522]
  • Marta Elena Hernández-Caballero, José Alfredo Sierra-Ramírez, Ricardo Villalobos-Valencia, Emmanuel Seseña-Méndez. Potential of Kalanchoe pinnata as a Cancer Treatment Adjuvant and an Epigenetic Regulator. Molecules (Basel, Switzerland). 2022 Sep; 27(19):. doi: 10.3390/molecules27196425. [PMID: 36234962]
  • Vandana Thotathil, Hanan Hosni Rizk, Ameena Fakrooh, Lakshmaiah Sreerama. Phytochemical Analysis of Acaciaehrenbergiana (Hayne) Grown in Qatar: Identification of Active Ingredients and Their Biological Activities. Molecules (Basel, Switzerland). 2022 Sep; 27(19):. doi: 10.3390/molecules27196400. [PMID: 36234937]
  • Shudh Kirti Dolma, S G Eswara Reddy. Characterization of Triadica sebifera (L.) Small Extracts, Antifeedant Activities of Extracts, Fractions, Seed Oil and Isolated Compounds against Plutella xylostella (L.) and Their Effect on Detoxification Enzymes. Molecules (Basel, Switzerland). 2022 Sep; 27(19):. doi: 10.3390/molecules27196239. [PMID: 36234776]
  • Julia Kühn, Corinna Brandsch, Mikis Kiourtzidis, Anika Nier, Simone Bieler, Bertrand Matthäus, Carola Griehl, Gabriele I Stangl. Microalgae-derived sterols do not reduce the bioavailability of oral vitamin D3 in mice. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2022 Sep; ?(?):. doi: 10.1024/0300-9831/a000766. [PMID: 36124519]
  • Sania Ashrafi, Safaet Alam, Nazim Uddin Emon, Monira Ahsan. Isolation, Characterization and Pharmacological Investigations of a New Phenolic Compound along with Four Others Firstly Reported Phytochemicals from Glycosmis cyanocarpa (Blume) Spreng. Molecules (Basel, Switzerland). 2022 Sep; 27(18):. doi: 10.3390/molecules27185972. [PMID: 36144708]
  • Umair Khurshid, Saeed Ahmad, Hammad Saleem, Arslan Hussain LodhI, Irfan Pervaiz, Mohsin Abbas Khan, Haroon Khan, Abdulwahab AlamrI, Mukhtar AnsarI, Marcello LocatellI, Muhammad Adeel Arshad, Muhammad Asif Wazir, Juwairiya Butt, Sirajudheen Anwar. Multifaced Assessment of Antioxidant Power, Phytochemical Metabolomics, In-Vitro Biological Potential and In-Silico Studies of Neurada procumbens L.: An Important Medicinal Plant. Molecules (Basel, Switzerland). 2022 Sep; 27(18):. doi: 10.3390/molecules27185849. [PMID: 36144585]
  • Dong-Yue Zhou, Yun-Hua Fu, Fang-Tong Li, Di Yang, Li-Na Wei, Hao Yue, Yu-Lin Dai, You-Jin Jeon. Treatment of Obese Zebrafish with Saringosterol Acetate through AMP Activated Protein Kinase Pathway. Chemistry & biodiversity. 2022 Sep; 19(9):e202200495. doi: 10.1002/cbdv.202200495. [PMID: 35856892]
  • Yugang Liu, Shuangshuang Ma, Huiping Xia, Shiyin Guo, Chaoxi Zeng. Edible oleogels stabilized solely by stigmasterol: effect of oil type and gelator concentration. Journal of the science of food and agriculture. 2022 Aug; 102(11):4759-4769. doi: 10.1002/jsfa.11841. [PMID: 35218222]
  • Li Huang, Guiming Li, Qiaoling Wang, Qian Meng, Fan Xu, Qian Chen, Fang Liu, Yulin Hu, Ming Luo. GhCYP710A1 Participates in Cotton Resistance to Verticillium Wilt by Regulating Stigmasterol Synthesis and Plasma Membrane Stability. International journal of molecular sciences. 2022 Jul; 23(15):. doi: 10.3390/ijms23158437. [PMID: 35955570]
  • Mandana AmeliMojarad, Melika AmeliMojarad, Alireza Pourmahdian. The inhibitory role of stigmasterol on tumor growth by inducing apoptosis in Balb/c mouse with spontaneous breast tumor (SMMT). BMC pharmacology & toxicology. 2022 06; 23(1):42. doi: 10.1186/s40360-022-00578-2. [PMID: 35725497]
  • Zhiyi Zhang, Juan Wang, Bingying Liu, Yu Liu, Xiaowei Shi, Wenli Li, Huawei Xin, Jie Xin, Chunxiang Hao. Anticancer effects of herbal medicines in pancreatic ductal adenocarcinoma through modulation of steroid hormone response proteins. Scientific reports. 2022 06; 12(1):9910. doi: 10.1038/s41598-022-14174-1. [PMID: 35701649]
  • Han-Biao Wu, Yu-Gang Xiao, Ji-Sheng Chen, Zhi-Kun Qiu. The potential mechanism of Bupleurum against anxiety was predicted by network pharmacology study and molecular docking. Metabolic brain disease. 2022 06; 37(5):1609-1639. doi: 10.1007/s11011-022-00970-1. [PMID: 35366129]
  • Olga A Rozentsvet, Ekaterina R Kotlova, Elena S Bogdanova, Viktor N Nesterov, Svetlana V Senik, Aleksey L Shavarda. Balance of Δ5-and Δ7-sterols and stanols in halophytes in connection with salinity tolerance. Phytochemistry. 2022 Jun; 198(?):113156. doi: 10.1016/j.phytochem.2022.113156. [PMID: 35248579]
  • Witold Gładkowski, Aleksandra Włoch, Hanna Pruchnik, Anna Chojnacka, Aleksandra Grudniewska, Agnieszka Wysota, Anna Dunal, Daniel Rubiano Castro, Magdalena Rudzińska. Acylglycerols of Myristic Acid as New Candidates for Effective Stigmasterol Delivery-Design, Synthesis, and the Influence on Physicochemical Properties of Liposomes. Molecules (Basel, Switzerland). 2022 May; 27(11):. doi: 10.3390/molecules27113406. [PMID: 35684341]
  • Otilia Frasinariu, Roxana Serban, Laura Mihaela Trandafir, Ingrith Miron, Magdalena Starcea, Ioana Vasiliu, Anna Alisi, Oana Raluca Temneanu. The Role of Phytosterols in Nonalcoholic Fatty Liver Disease. Nutrients. 2022 May; 14(11):. doi: 10.3390/nu14112187. [PMID: 35683987]
  • Pengrui Wang, Junfang Zhang, Na Zhan, Shuang Yang, Mingming Yu, Hongbing Liu. The pharmacokinetic characteristics and excretion studies of fucosterol from Sargasssum fusiforme in rats. Biomedical chromatography : BMC. 2022 Apr; 36(4):e5309. doi: 10.1002/bmc.5309. [PMID: 34981527]
  • Maqsood Ahmed, Allah Rakha Sajid, Ansar Javeed, Muhammad Aslam, Taswar Ahsan, Dilbar Hussain, Abdul Mateen, Xiuwei Li, Peiwen Qin, Mingshan Ji. Antioxidant, antifungal, and aphicidal activity of the triterpenoids spinasterol and 22,23-dihydrospinasterol from leaves of Citrullus colocynthis L. Scientific reports. 2022 03; 12(1):4910. doi: 10.1038/s41598-022-08999-z. [PMID: 35318417]
  • Paul Djouonzo Toukam, Christelle Wayoue Kom, Armelle Deutou Tchamgoué, Estelle Aurelie Kamgang Doupno, Younoussa Lame, Lauve Rachel Tchokouaha Yamthé, Théodora Kopa Kowa, Alembert Tiabou Tchinda, Michel Fredérich, Joseph Tanyi Mbafor, Alex De Théodore Atchadé. A new isoquinoline and ceramide from the stem barks of Discoglypremna caloneura (Pax) Prain (Euphorbiaceae) with antiproteinase and cytotoxic activities. Natural product research. 2022 Mar; 36(6):1543-1551. doi: 10.1080/14786419.2021.1890073. [PMID: 33624570]
  • Piao Zheng, Zhen Huang, Dong-Chang Tong, Qing Zhou, Sha Tian, Bo-Wei Chen, Di-Min Ning, Yin-Mei Guo, Wen-Hao Zhu, Yan Long, Wei Xiao, Zhe Deng, Yi-Chen Lei, Xue-Fei Tian. Frankincense myrrh attenuates hepatocellular carcinoma by regulating tumor blood vessel development through multiple epidermal growth factor receptor-mediated signaling pathways. World journal of gastrointestinal oncology. 2022 Feb; 14(2):450-477. doi: 10.4251/wjgo.v14.i2.450. [PMID: 35317323]
  • Ge Bai, Chuan-Guo Ma, Xiao-Wei Chen, Yu-Yuan Hu, Shu-Jing Guo. Thermal degradation of stigmasterol under the deodorisation temperature exposure alone and in edible corn oil. Food chemistry. 2022 Feb; 370(?):131030. doi: 10.1016/j.foodchem.2021.131030. [PMID: 34507209]
  • Xingyu Lu, Amila A Dissanayake, Chuqiao Xiao, Jie Gao, Mouming Zhao, Muraleedharan G Nair. The edible seaweed Laminaria japonica contains cholesterol analogues that inhibit lipid peroxidation and cyclooxygenase enzymes. PloS one. 2022 ; 17(1):e0258980. doi: 10.1371/journal.pone.0258980. [PMID: 35085233]
  • Roshamur Cahyan Forestrania, Gerardo D Anaya-Eugenio, Ulyana Muñoz Acuña, Yulin Ren, Berna Elya, Esperanza Carcache de Blanco. Secondary metabolites from Garcinia daedalanthera Pierre leaves (Clusiaceae). Natural product research. 2022 Jan; 36(1):207-213. doi: 10.1080/14786419.2020.1777117. [PMID: 32530310]
  • Siti N H Muhammad, Nik S Yaacob, Nur A M Safuwan, Agustine N Fauzi. Antiglycolytic Activities of Strobilanthes crispus Active Fraction and its Bioactive Components on Triple-Negative Breast Cancer Cells In Vitro. Anti-cancer agents in medicinal chemistry. 2022; 22(7):1363-1369. doi: 10.2174/1871520621666210427104804. [PMID: 33906591]
  • Zhi-Zhao Li, Qiong Huang, Xiao-Li Yang, Jieqiong Zeng, Qi-Hui Wang, Hai-Ming Tang, Zhen-Qiu Yu, Yu-Qing Song, Yang Liu. Cholesterol Metabolic Markers for Differential Evaluation of Patients with Hyperlipidemia and Familial Hypercholesterolemia. Disease markers. 2022; 2022(?):2008556. doi: 10.1155/2022/2008556. [PMID: 35493299]
  • Abigail Hohoayi, Aaron O Antwi, Veronica Amoah, Newman Osafo, Paul P O Sampene, George Ainooson. Coadministration of Stigmasterol and Dexamethasone (STIG+DEX) Modulates Steroid-Resistant Asthma. Mediators of inflammation. 2022; 2022(?):2222270. doi: 10.1155/2022/2222270. [PMID: 36060927]
  • Sourav Ghosh, Arvind Kumar, Neetu Sachan, Phool Chandra. Evaluation of the Antidepressant-like Effect of Total Sterols Fraction and Stigmasterol Isolated from Leaves of Aegle marmelos and Possible Mechanism( s) of Action Involved. Current drug discovery technologies. 2022; 19(2):e290721195144. doi: 10.2174/1570163818666210729165310. [PMID: 34376134]
  • Deeksha Salaria, Rajan Rolta, Jyoti Mehta, Oladoja Awofisayo, Olatomide A Fadare, Baljinder Kaur, Balvir Kumar, Renato Araujo da Costa, Shikha Rangra Chandel, Neha Kaushik, Eun Ha Choi, Nagendra Kumar Kaushik. Phytoconstituents of traditional Himalayan Herbs as potential inhibitors of Human Papillomavirus (HPV-18) for cervical cancer treatment: An In silico Approach. PloS one. 2022; 17(3):e0265420. doi: 10.1371/journal.pone.0265420. [PMID: 35298541]
  • Hai-Li Li, Jian-Peng Zhou, Jing-Min Deng. Therapeutic Mechanism of Xiaoqinglong Decoction against COVID-19 Based on Network Pharmacology and Molecular Docking Technology. Combinatorial chemistry & high throughput screening. 2022; 25(13):2264-2277. doi: 10.2174/1386207325666220228154231. [PMID: 35227178]
  • Magdalena Rudzińska, Aleksandra Grudniewska, Anna Chojnacka, Witold Gładkowski, Gabriela Maciejewska, Anna Olejnik, Katarzyna Kowalska. Distigmasterol-Modified Acylglycerols as New Structured Lipids-Synthesis, Identification and Cytotoxicity. Molecules (Basel, Switzerland). 2021 Nov; 26(22):. doi: 10.3390/molecules26226837. [PMID: 34833929]
  • Niti Sharma, Mario A Tan, Seong Soo A An. Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases. International journal of molecular sciences. 2021 Nov; 22(22):. doi: 10.3390/ijms222212255. [PMID: 34830148]
  • Yufang Lu, Herbert J Kronzucker, Weiming Shi. Stigmasterol root exudation arising from Pseudomonas inoculation of the duckweed rhizosphere enhances nitrogen removal from polluted waters. Environmental pollution (Barking, Essex : 1987). 2021 Oct; 287(?):117587. doi: 10.1016/j.envpol.2021.117587. [PMID: 34182390]
  • Nasiara Karim, Imran Khan, Abeer Abdelhalim, Sobia Ahsan Halim, Ajmal Khan, Ahmed Al-Harrasi. Stigmasterol can be new steroidal drug for neurological disorders: Evidence of the GABAergic mechanism via receptor modulation. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2021 Sep; 90(?):153646. doi: 10.1016/j.phymed.2021.153646. [PMID: 34280827]
  • Kenneth Vanbrabant, David Van Meel, Anja Kerksiek, Silvia Friedrichs, Marco Dubbeldam, Melissa Schepers, Na Zhan, Katharina Gutbrod, Peter Dörmann, Hong-Bing Liu, Monique T Mulder, Tim Vanmierlo, Dieter Lütjohann. 24(R, S)-Saringosterol - From artefact to a biological medical agent. The Journal of steroid biochemistry and molecular biology. 2021 09; 212(?):105942. doi: 10.1016/j.jsbmb.2021.105942. [PMID: 34144153]
  • Daniel Pushparaju Yeggoni, Shreya Dubey, Yusuf Zamal Mohammad, Aparna Rachamallu, Rajagopal Subramanyam. Elucidation of binding mechanism of stigmasterol with human serum albumin: a biophysical and molecular dynamics simulation approach. Journal of biomolecular structure & dynamics. 2021 Aug; ?(?):1-13. doi: 10.1080/07391102.2021.1968498. [PMID: 34463217]
  • Ying Yan, Zhoumin Niu, Boyang Wang, Shangge Zhao, Chao Sun, Yuting Wu, Yuying Li, Hao Ying, Hongbing Liu. Saringosterol from Sargassum fusiforme Modulates Cholesterol Metabolism and Alleviates Atherosclerosis in ApoE-Deficient Mice. Marine drugs. 2021 Aug; 19(9):. doi: 10.3390/md19090485. [PMID: 34564147]
  • Fabio Ferrini, Daniele Fraternale, Sabrina Donati Zeppa, Giancarlo Verardo, Andrea Gorassini, Vittoria Carrabs, Maria Cristina Albertini, Piero Sestili. Yield, Characterization, and Possible Exploitation of Cannabis Sativa L. Roots Grown under Aeroponics Cultivation. Molecules (Basel, Switzerland). 2021 Aug; 26(16):. doi: 10.3390/molecules26164889. [PMID: 34443479]
  • Nattaporn Pattarachotanant, Anchalee Prasansuklab, Tewin Tencomnao. Momordica charantia L. Extract Protects Hippocampal Neuronal Cells against PAHs-Induced Neurotoxicity: Possible Active Constituents Include Stigmasterol and Vitamin E. Nutrients. 2021 Jul; 13(7):. doi: 10.3390/nu13072368. [PMID: 34371875]
  • Ye-Jin Kim, So-Yeon Jeon, Jae-Sue Choi, Na-Hyun Kim, Yukiori Goto, Young-A Lee. Alterations of amygdala-prefrontal cortical coupling and attention deficit/hyperactivity disorder-like behaviors induced by neonatal habenula lesion: normalization by Ecklonia stolonifera extract and its active compound fucosterol. Behavioural pharmacology. 2021 06; 32(4):308-320. doi: 10.1097/fbp.0000000000000620. [PMID: 33491993]
  • Yingying Shi, Dongdong Zhang, Shupei Li, Xiuxiu Xuan, Liuqiang Zhang, Yiming Li, Fujiang Guo. Inhibitors of BRD4 protein from the roots of Astilbe grandis stapf ex E.H. Wilson. Natural product research. 2021 Jun; 35(12):2044-2050. doi: 10.1080/14786419.2019.1655414. [PMID: 31437007]
  • Rosa Pireddu, Chiara Sinico, Guido Ennas, Donatella Valenti, Francesca Marongiu, Anna Maria Fadda, Michele Schlich, Francesco Lai. Nanocrystals as Tool to Enhance Stigmasterol Oral Bioavailability. Journal of nanoscience and nanotechnology. 2021 05; 21(5):2946-2948. doi: 10.1166/jnn.2021.19046. [PMID: 33653464]
  • Nikita Martens, Melissa Schepers, Na Zhan, Frank Leijten, Gardi Voortman, Assia Tiane, Ben Rombaut, Janne Poisquet, Nienke van de Sande, Anja Kerksiek, Folkert Kuipers, Johan W Jonker, Hongbing Liu, Dieter Lütjohann, Tim Vanmierlo, Monique T Mulder. 24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer's Disease. Marine drugs. 2021 Mar; 19(4):. doi: 10.3390/md19040190. [PMID: 33801706]
  • Laura Gutiérrez-García, Montserrat Arró, Teresa Altabella, Albert Ferrer, Albert Boronat. Structural and functional analysis of tomato sterol C22 desaturase. BMC plant biology. 2021 Mar; 21(1):141. doi: 10.1186/s12870-021-02898-7. [PMID: 33731007]
  • Hayet Saidani, Marc Léonetti, Hanna Kmita, Fabrice Homblé. The Open State Selectivity of the Bean Seed VDAC Depends on Stigmasterol and Ion Concentration. International journal of molecular sciences. 2021 Mar; 22(6):. doi: 10.3390/ijms22063034. [PMID: 33809742]
  • Sangeeta V Alagasamy, Surash Ramanathan, Nelson Jeng-Yeou Chear, Wen-Nee Tan, Dinesh Sangarran Ramachandram, Ai-Fein T Ching-Ga, Yasodha Ponnusamy, Choon-Sheen Lai, Vikneswaran Murugaiyah. The potentiation of beta-lactam and anti-bacterial activities of lipophilic constituents from Mesua ferrae leaves against methicillin-resistant Staphylococcus aureus. Journal of complementary & integrative medicine. 2021 Jan; 18(2):339-345. doi: 10.1515/jcim-2019-0316. [PMID: 34187118]
  • Shuting Wen, Long He, Zhuotai Zhong, Runyuan Zhao, Senhui Weng, Hong Mi, Fengbin Liu. Stigmasterol Restores the Balance of Treg/Th17 Cells by Activating the Butyrate-PPARγ Axis in Colitis. Frontiers in immunology. 2021; 12(?):741934. doi: 10.3389/fimmu.2021.741934. [PMID: 34691046]
  • Nada H Aljarba, Huma Ali, Saad Alkahtani. Synergistic Dose Permutation of Isolated Alkaloid and Sterol for Anticancer Effect on Young Swiss Albino Mice. Drug design, development and therapy. 2021; 15(?):4043-4052. doi: 10.2147/dddt.s322769. [PMID: 34588765]
  • Meng Li, Wenqi Zhang, Linqi Yang, Huibing Wang, Yihan Wang, Kai Huang, Wei Zhang. The Mechanism of Xiaoyao San in the Treatment of Ovarian Cancer by Network Pharmacology and the Effect of Stigmasterol on the PI3K/Akt Pathway. Disease markers. 2021; 2021(?):4304507. doi: 10.1155/2021/4304507. [PMID: 34306252]
  • Takeo Yamaguchi, Chiharu Manaka, Ayaka Ogura, Shigemi Nagadome. Importance of Cholesterol Side Chain in the Membrane Stability of Human Erythrocytes. Biological & pharmaceutical bulletin. 2021; 44(6):888-893. doi: 10.1248/bpb.b21-00134. [PMID: 34078822]
  • Arti Sharma, Satiander Rana, Gulzar A Rather, Prashant Misra, Manoj K Dhar, Surrinder K Lattoo. Characterization and overexpression of sterol Δ22-desaturase, a key enzyme modulates the biosyntheses of stigmasterol and withanolides in Withania somnifera (L.) Dunal. Plant science : an international journal of experimental plant biology. 2020 Dec; 301(?):110642. doi: 10.1016/j.plantsci.2020.110642. [PMID: 33218619]
  • Trang T T Nguyen, Ha V H Nguyen. Effects of Fermentation Conditions Using Lactobacillus plantarum on the Charantin, Stigmasterol Glucoside and β-sitosterol Glucoside Contents of Bitter Gourd (Momordica charantia L.) Juice. Plant foods for human nutrition (Dordrecht, Netherlands). 2020 Dec; 75(4):656-658. doi: 10.1007/s11130-020-00860-w. [PMID: 33009632]
  • Beibei Zhao, Yan Zhang, Hua Li, Jiawen Deng, Haodi Gong, Zhicheng Chen. Nutritional Component and Chemical Characterization of Chinese Highland Barley Bran Oil. Journal of oleo science. 2020 Nov; 69(11):1339-1347. doi: 10.5650/jos.ess19318. [PMID: 33055435]
  • Takeru Koga, Takaiku Sakamoto, Eiji Sakuradani, Akihiro Tai. Neurite Outgrowth-Promoting Activity of Compounds in PC12 Cells from Sunflower Seeds. Molecules (Basel, Switzerland). 2020 Oct; 25(20):. doi: 10.3390/molecules25204748. [PMID: 33081156]
  • Mahmood Ahmad Khan, Abu Hasnath Md Golam Sarwar, Rani Rahat, Rafat Sultana Ahmed, Sadiq Umar. Stigmasterol protects rats from collagen induced arthritis by inhibiting proinflammatory cytokines. International immunopharmacology. 2020 Aug; 85(?):106642. doi: 10.1016/j.intimp.2020.106642. [PMID: 32470883]
  • Fang Liu, Xiaoping Zhang, Mingdao Wang, Lele Guo, Yingyue Yang, Mingqin Zhao. Biosorption of sterols from tobacco waste extract using living and dead of newly isolated fungus Aspergillus fumigatus strain LSD-1. Bioscience, biotechnology, and biochemistry. 2020 Jul; 84(7):1521-1528. doi: 10.1080/09168451.2020.1742089. [PMID: 32183612]
  • Josep M Llop-Talaveron, Elisabet Leiva-Badosa, Ana Novak, Raúl Rigo-Bonnin, Josep R Ticó-Grau, Josep M Suñé-Negre, Ana Suárez-Lledó, Toni Lozano-Andreu, Maria B Badía-Tahull. Phytosterolaemia associated with parenteral nutrition administration in adult patients. The British journal of nutrition. 2020 06; 123(12):1365-1372. doi: 10.1017/s0007114520000574. [PMID: 32077392]
  • Abdirahman Elmi, Rosella Spina, Arnaud Risler, Stéphanie Philippot, Ali Mérito, Raphaël E Duval, Fatouma Mohamed Abdoul-Latif, Dominique Laurain-Mattar. Evaluation of Antioxidant and Antibacterial Activities, Cytotoxicity of Acacia seyal Del Bark Extracts and Isolated Compounds. Molecules (Basel, Switzerland). 2020 May; 25(10):. doi: 10.3390/molecules25102392. [PMID: 32455580]