patulin (BioDeep_00000407549)

 

Secondary id: BioDeep_00000003862, BioDeep_00001871287

natural product PANOMIX_OTCML-2023


代谢物信息卡片


patulin

化学式: C7H6O4 (154.0266)
中文名称: 棒曲霉素
谱图信息: 最多检出来源 Homo sapiens(natural_products) 1.89%

分子结构信息

SMILES: C1C=C2C(=CC(=O)O2)C(O1)O
InChI: InChI=1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2

描述信息

D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins
CONFIDENCE standard compound; INTERNAL_ID 5971
D009676 - Noxae > D009153 - Mutagens
CONFIDENCE Reference Standard (Level 1)
Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, is suspected to be clastogenic, mutagenic, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage[1][2][3][4].

同义名列表

4 个代谢物同义名

patulin; Terinin; Patulin; Patulin



数据库引用编号

34 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

235 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 AKT1, BCL2, CASP3, CASP9, CAT, DCTN4, HPGDS, MAPK8, MARVELD1, PPARG, PTGS2, TJP1
Peripheral membrane protein 3 CTSB, PTGS2, TJP1
Endoplasmic reticulum membrane 2 BCL2, PTGS2
Nucleus 10 AKT1, BCL2, CASP3, CASP9, DCTN4, JUN, MAPK8, MARVELD1, PPARG, TJP1
cytosol 12 AKT1, BCL2, CASP3, CASP9, CAT, DCTN4, GPT, GSR, HPGDS, MAPK8, PPARG, TJP1
centrosome 1 DCTN4
nucleoplasm 7 AKT1, ATP2B1, CASP3, HPGDS, JUN, MAPK8, PPARG
RNA polymerase II transcription regulator complex 2 JUN, PPARG
Cell membrane 5 AKT1, ATP2B1, CD69, MARVELD1, TJP1
Cytoplasmic side 1 TJP1
lamellipodium 1 AKT1
Multi-pass membrane protein 2 ATP2B1, MARVELD1
Synapse 2 ATP2B1, MAPK8
cell cortex 2 AKT1, DCTN4
cell junction 1 TJP1
glutamatergic synapse 3 AKT1, ATP2B1, CASP3
neuronal cell body 1 CASP3
postsynapse 1 AKT1
presynaptic membrane 1 ATP2B1
Lysosome 1 CTSB
plasma membrane 5 AKT1, ATP2B1, CD69, MARVELD1, TJP1
synaptic vesicle membrane 1 ATP2B1
Membrane 5 AKT1, ATP2B1, BCL2, CAT, MARVELD1
apical plasma membrane 2 CTSB, TJP1
axon 1 MAPK8
basolateral plasma membrane 2 ATP2B1, TJP1
caveola 1 PTGS2
extracellular exosome 5 ATP2B1, CAT, CTSB, GPT, GSR
endoplasmic reticulum 2 BCL2, PTGS2
extracellular space 3 CTSB, IL6, PNLIP
perinuclear region of cytoplasm 2 CTSB, PPARG
Cell junction, tight junction 1 TJP1
adherens junction 1 TJP1
apicolateral plasma membrane 1 TJP1
bicellular tight junction 1 TJP1
gap junction 1 TJP1
intercalated disc 1 TJP1
intercellular canaliculus 1 TJP1
mitochondrion 5 BCL2, CASP9, CAT, GSR, TJP1
protein-containing complex 7 AKT1, BCL2, CASP9, CAT, CD69, PTGS2, TJP1
intracellular membrane-bounded organelle 4 ATP2B1, CAT, HPGDS, PPARG
Microsome membrane 1 PTGS2
postsynaptic density 1 CASP3
Secreted 2 IL6, PNLIP
extracellular region 4 CAT, CTSB, IL6, PNLIP
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
mitochondrial matrix 2 CAT, GSR
Extracellular side 1 CTSB
transcription regulator complex 1 JUN
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 DCTN4
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 3 CD69, CTSB, GSR
microtubule cytoskeleton 1 AKT1
apical part of cell 1 TJP1
cell-cell junction 1 AKT1
Single-pass type II membrane protein 1 CD69
vesicle 1 AKT1
Apical cell membrane 1 CTSB
pore complex 1 BCL2
Cytoplasm, cytoskeleton 2 DCTN4, MARVELD1
focal adhesion 2 CAT, DCTN4
spindle 1 AKT1
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 1 CTSB
lateral plasma membrane 1 ATP2B1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Cytoplasm, myofibril, sarcomere 1 DCTN4
sarcomere 1 DCTN4
receptor complex 1 PPARG
neuron projection 1 PTGS2
ciliary basal body 1 AKT1
chromatin 2 JUN, PPARG
cell projection 2 ATP2B1, TJP1
cytoskeleton 1 MARVELD1
Cell projection, podosome 1 TJP1
podosome 1 TJP1
Secreted, extracellular space 1 CTSB
spindle pole 1 DCTN4
nuclear chromosome 1 JUN
Cytoplasm, cell cortex 1 DCTN4
Basolateral cell membrane 1 ATP2B1
Melanosome 1 CTSB
euchromatin 1 JUN
Presynaptic cell membrane 1 ATP2B1
myelin sheath 1 BCL2
stress fiber 1 DCTN4
ficolin-1-rich granule lumen 2 CAT, CTSB
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 2 IL6, PTGS2
dynactin complex 1 DCTN4
kinetochore 1 DCTN4
tight junction 1 TJP1
immunological synapse 1 ATP2B1
cytoplasmic dynein complex 1 DCTN4
apoptosome 1 CASP9
Cytoplasm, cytoskeleton, stress fiber 1 DCTN4
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
apical junction complex 1 TJP1
peptidase inhibitor complex 1 CTSB
transcription factor AP-1 complex 1 JUN
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
endolysosome lumen 1 CTSB
BAD-BCL-2 complex 1 BCL2
photoreceptor ribbon synapse 1 ATP2B1
caspase complex 1 CASP9


文献列表

  • Tristan W Wang, Amanda G Wilson, Gregory M Peck, Patrick A Gibney, Kathie T Hodge. Patulin contamination of hard apple cider by Paecilomyces niveus and other postharvest apple pathogens: Assessing risk factors. International journal of food microbiology. 2024 Feb; 412(?):110545. doi: 10.1016/j.ijfoodmicro.2023.110545. [PMID: 38237417]
  • Shuang Li, Shubing Chen, Yanan Meng, Shun Zhang, Ting Cai. Identification and pretreatment analysis of endogenous degradation products of patulin in zebrafish. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024 Feb; 184(?):114414. doi: 10.1016/j.fct.2023.114414. [PMID: 38128688]
  • Meiqiu Xu, Esa Abiso Godana, Jingyu Li, Yaping Deng, Yufei Ma, Huiyuan Ya, Hongyin Zhang. Infection of postharvest pear by Penicillium expansum is facilitated by the glycoside hydrolase (eglB) gene. International journal of food microbiology. 2024 Jan; 410(?):110465. doi: 10.1016/j.ijfoodmicro.2023.110465. [PMID: 37980812]
  • Mengna Zhang, Na Liu, Fengshou Dong, Liping Wang, Jun Xu, Xiaohu Wu, Yongquan Zheng, Xinglu Pan. The fate of mycotoxins in oranges during storage and processing. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2023 Dec; 40(12):1614-1624. doi: 10.1080/19440049.2023.2282555. [PMID: 38011597]
  • Cong Song, Yang Zhang, Qian Zhao, Mengyao Chen, Yu Zhang, Congcong Gao, Zhenhua Jia, Shuishan Song, Junfeng Guan, Zhonglin Shang. Volatile organic compounds produced by Bacillus aryabhattai AYG1023 against Penicillium expansum causing blue mold on the Huangguan pear. Microbiological research. 2023 Oct; 278(?):127531. doi: 10.1016/j.micres.2023.127531. [PMID: 37871540]
  • Dianiris Luciano-Rosario, Omer Barda, Joanna Tannous, Dean Frawley, Özgür Bayram, Dov Prusky, Edward Sionov, Nancy P Keller. The histone demethylase KdmB is part of a trimeric protein complex and mediates virulence and mycotoxin production in Penicillium expansum. Fungal genetics and biology : FG & B. 2023 Sep; ?(?):103837. doi: 10.1016/j.fgb.2023.103837. [PMID: 37722619]
  • Seungmin Yu, Ji-Hye Song, Hee Soo Kim, Seulmin Hong, Seon Kyeong Park, Soo Hyun Park, Jangho Lee, Young Chan Chae, Jae Ho Park, Yu Geon Lee. Patulin alleviates hepatic lipid accumulation by regulating lipogenesis and mitochondrial respiration. Life sciences. 2023 Aug; 326(?):121816. doi: 10.1016/j.lfs.2023.121816. [PMID: 37271452]
  • Wen-Chang Sun, Ning-Ning Wang, Ru Li, Xian-Ce Sun, Jia-Wei Liao, Guang Yang, Shuang Liu. Ferritinophagy activation and sideroflexin1-dependent mitochondrial iron overload contribute to patulin-induced cardiac inflammation and fibrosis. The Science of the total environment. 2023 May; ?(?):164472. doi: 10.1016/j.scitotenv.2023.164472. [PMID: 37257617]
  • Mengyang Xing, Yong Chen, Wanqin Dai, Xiao He, Boqiang Li, Shiping Tian. Immobilized short-chain dehydrogenase/reductase on Fe3O4 particles acts as a magnetically recoverable biocatalyst component in patulin bio-detoxification system. Journal of hazardous materials. 2023 Apr; 448(?):130986. doi: 10.1016/j.jhazmat.2023.130986. [PMID: 36860057]
  • Xiaodi Xu, Yong Chen, Boqiang Li, Shiping Tian. Histone H3K4 Methyltransferase PeSet1 Regulates Colonization, Patulin Biosynthesis, and Stress Responses of Penicillium expansum. Microbiology spectrum. 2023 Feb; 11(1):e0354522. doi: 10.1128/spectrum.03545-22. [PMID: 36633412]
  • Jihui Xi, Dongyun Yang, Huali Xue, Zhiguang Liu, Yang Bi, Yuan Zhang, Xi Yang, Suqin Shang. Isolation of the Main Pathogens Causing Postharvest Disease in Fresh Angelica sinensis during Different Storage Stages and Impacts of Ozone Treatment on Disease Development and Mycotoxin Production. Toxins. 2023 Feb; 15(2):. doi: 10.3390/toxins15020154. [PMID: 36828468]
  • Zhaoyuan Gong, Yueming Huang, Xianjing Hu, Jianye Zhang, Qilei Chen, Hubiao Chen. Recent Progress in Electrochemical Nano-Biosensors for Detection of Pesticides and Mycotoxins in Foods. Biosensors. 2023 Jan; 13(1):. doi: 10.3390/bios13010140. [PMID: 36671974]
  • Huimin Li, Yang Zhang, Congcong Gao, Qi Gao, Yudou Cheng, Min Zhao, Junfeng Guan. Mycotoxin Production and the Relationship between Microbial Diversity and Mycotoxins in Pyrus bretschneideri Rehd cv. Huangguan Pear. Toxins. 2022 Oct; 14(10):. doi: 10.3390/toxins14100699. [PMID: 36287968]
  • Hui Chen, Lixing Cao, Kai Han, Han Zhang, Jinling Cui, Xuan Ma, Shuang Zhao, Chong Zhao, Shutao Yin, Lihong Fan, Hongbo Hu. Patulin disrupts SLC7A11-cystine-cysteine-GSH antioxidant system and promotes renal cell ferroptosis both in vitro and in vivo. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022 Aug; 166(?):113255. doi: 10.1016/j.fct.2022.113255. [PMID: 35772596]
  • Meiqiu Xu, Qidi Zhang, Solairaj Dhanasekaran, Esa Abiso Godana, Xiaoyun Zhang, Qiya Yang, Lina Zhao, Hongyin Zhang. The necrosis-inducing protein (NIP) gene contributes to Penicillium expansum virulence during postharvest pear infection. Food research international (Ottawa, Ont.). 2022 08; 158(?):111562. doi: 10.1016/j.foodres.2022.111562. [PMID: 35840251]
  • Saurabh Pal, Deviprasad Rendedula, Narendra Kumar Nagendla, Muralidharan Kaliyaperumal, Mohana Krishna Reddy Mudiam, Kausar Mahmood Ansari. Serum and urine metabolomics analysis reveals the role of altered metabolites in patulin-induced nephrotoxicity. Food research international (Ottawa, Ont.). 2022 06; 156(?):111177. doi: 10.1016/j.foodres.2022.111177. [PMID: 35651038]
  • Mengyang Xing, Yong Chen, Boqiang Li, Shiping Tian. Highly efficient removal of patulin using immobilized enzymes of Pseudomonas aeruginosa TF-06 entrapped in calcium alginate beads. Food chemistry. 2022 May; 377(?):131973. doi: 10.1016/j.foodchem.2021.131973. [PMID: 34990945]
  • Yunfeng Hou, Shaopeng Wang, Liping Jiang, Xiance Sun, Jing Li, Ningning Wang, Xiaofang Liu, Xiaofeng Yao, Cong Zhang, Haoyuan Deng, Guang Yang. Patulin Induces Acute Kidney Injury in Mice through Autophagy-Ferroptosis Pathway. Journal of agricultural and food chemistry. 2022 May; 70(20):6213-6223. doi: 10.1021/acs.jafc.1c08349. [PMID: 35543324]
  • Holly P Bartholomew, Michael J Bradshaw, Otilia Macarisin, Verneta L Gaskins, Jorge M Fonseca, Wayne M Jurick. More than a Virulence Factor: Patulin Is a Non-Host-Specific Toxin that Inhibits Postharvest Phytopathogens and Requires Efflux for Penicillium Tolerance. Phytopathology. 2022 May; 112(5):1165-1174. doi: 10.1094/phyto-09-21-0371-r. [PMID: 35365059]
  • Yashodani Pillay, Savania Nagiah, Charlette Tiloke, Alisa Phulukdaree, Anil A Chuturgoon. miR-27b inhibition contributes to cytotoxicity in patulin-exposed HEK293 cells. Toxicon : official journal of the International Society on Toxinology. 2022 Apr; 210(?):58-65. doi: 10.1016/j.toxicon.2022.02.018. [PMID: 35217024]
  • Hai Li, Candi Liu, Shurong Luo, Sijie Zhu, Shan Tang, Huimei Zeng, Yu Qin, Ming Ma, Dong Zeng, Teris A van Beek, Hui Wang, Bo Chen. Chromatographic Determination of the Mycotoxin Patulin in 219 Chinese Tea Samples and Implications for Human Health. Molecules (Basel, Switzerland). 2022 Apr; 27(9):. doi: 10.3390/molecules27092852. [PMID: 35566203]
  • Baigang Zhang, Chenghui Huang, Qikun Lu, Hairong Liang, Jinliang Li, Dongmei Xu. Involvement of caspase in patulin-induced hepatotoxicity in vitro and in vivo. Toxicon : official journal of the International Society on Toxinology. 2022 Jan; 206(?):64-73. doi: 10.1016/j.toxicon.2021.12.017. [PMID: 34968565]
  • Nan Zhang, Jingrong Li, Boshi Liu, Haixia Wang, Di Zhang, Zheng Li. A facile 'turn-on' fluorescent aptasensor for simultaneous detection of dual mycotoxins in traditional Chinese medicine based on graphene oxide and FRET. Toxicon : official journal of the International Society on Toxinology. 2022 Jan; 206(?):42-50. doi: 10.1016/j.toxicon.2021.12.006. [PMID: 34902366]
  • Ingrid D Dos Santos, Marlos E Z Fontana, Bruna Klein, Stephanie R Ribeiro, Andrieli Stefanello, Fabio R Thewes, Suele F P Schmidt, Marina V Copetti, Auri Brackmann, Ionara R Pizzutti, Roger Wagner. Fungal growth, patulin accumulation and volatile profile in 'Fuji Mishima' apples under controlled atmosphere and dynamic controlled atmosphere. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2022 Jan; 39(1):170-184. doi: 10.1080/19440049.2021.1987533. [PMID: 34702141]
  • Saurabh Pal, Neha Singh, Indra Dev, Vineeta Sharma, Pankaj Ramji Jagdale, Anjaneya Ayanur, Kausar Mahmood Ansari. TGF-β/Smad signaling pathway plays a crucial role in patulin-induced pro-fibrotic changes in rat kidney via modulation of slug and snail expression. Toxicology and applied pharmacology. 2022 01; 434(?):115819. doi: 10.1016/j.taap.2021.115819. [PMID: 34896196]
  • Tristan W Wang, Kathie T Hodge. Susceptibility of Rosaceous Pome and Stone Fruits to Postharvest Rot by Paecilomyces niveus. Plant disease. 2022 Jan; 106(1):121-126. doi: 10.1094/pdis-04-21-0855-re. [PMID: 34445878]
  • Yesica Lambrese, Gabriela Sansone, María Isabel Sanz, Susana Noemí Di Masi, Julio Raba, Viviana Calvente. Kosakonia radicincitans and Cryptococcus laurentii controlled Penicillium expansum rot and decreased patulin production at 4 and 25 °C. Food microbiology. 2021 Dec; 100(?):103863. doi: 10.1016/j.fm.2021.103863. [PMID: 34416963]
  • Husam Ibrahem Aroud, Bianca May, Helmut Dietrich, Ralf Schweiggert, Sabine Kemmlein. Influence of processing steps on the fate of ochratoxin A, patulin, and alternariol during production of cloudy and clear apple juices. Mycotoxin research. 2021 Nov; 37(4):341-354. doi: 10.1007/s12550-021-00443-x. [PMID: 34693499]
  • Wassim Habib, Mario Masiello, Hala Chahine-Tsouvalakis, Zahraa Al Moussawi, Carine Saab, Salwa Tohmé Tawk, Luca Piemontese, Michele Solfrizzo, Antonio Francesco Logrieco, Antonio Moretti, Antonia Susca. Occurrence and Characterization of Penicillium Species Isolated from Post-Harvest Apples in Lebanon. Toxins. 2021 10; 13(10):. doi: 10.3390/toxins13100730. [PMID: 34679023]
  • Ante Lončarić, Bojan Šarkanj, Ana-Marija Gotal, Marija Kovač, Ante Nevistić, Goran Fruk, Martina Skendrović Babojelić, Jurislav Babić, Borislav Miličević, Tihomir Kovač. Penicillium expansum Impact and Patulin Accumulation on Conventional and Traditional Apple Cultivars. Toxins. 2021 10; 13(10):. doi: 10.3390/toxins13100703. [PMID: 34678996]
  • Yong Chen, Zhanquan Zhang, Boqiang Li, Shiping Tian. PeMetR-mediated sulfur assimilation is essential for virulence and patulin biosynthesis in Penicillium expansum. Environmental microbiology. 2021 09; 23(9):5555-5568. doi: 10.1111/1462-2920.15704. [PMID: 34347341]
  • Jiayu Liu, Qi Liu, Jiahui Han, Jiayu Feng, Tianmin Guo, Zhiman Li, Fenyi Min, Ruyi Jin, Xiaoli Peng. N-Acetylcysteine Inhibits Patulin-Induced Apoptosis by Affecting ROS-Mediated Oxidative Damage Pathway. Toxins. 2021 08; 13(9):. doi: 10.3390/toxins13090595. [PMID: 34564600]
  • Berta Canal, Allison W McClure, Joseph F Curran, Mary Wu, Rachel Ulferts, Florian Weissmann, Jingkun Zeng, Agustina P Bertolin, Jennifer C Milligan, Souradeep Basu, Lucy S Drury, Tom D Deegan, Ryo Fujisawa, Emma L Roberts, Clovis Basier, Karim Labib, Rupert Beale, Michael Howell, John F X Diffley. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease. The Biochemical journal. 2021 07; 478(13):2445-2464. doi: 10.1042/bcj20210198. [PMID: 34198326]
  • Yanjing Guo, Weizhe Liu, He Wang, Xiaoxiong Wang, Sheng Qiang, Hazem M Kalaji, Reto Jörg Strasser, Shiguo Chen. Action Mode of the Mycotoxin Patulin as a Novel Natural Photosystem II Inhibitor. Journal of agricultural and food chemistry. 2021 Jul; 69(26):7313-7323. doi: 10.1021/acs.jafc.1c01811. [PMID: 34165302]
  • Mengyang Xing, Yong Chen, Boqiang Li, Shiping Tian. Characterization of a short-chain dehydrogenase/reductase and its function in patulin biodegradation in apple juice. Food chemistry. 2021 Jun; 348(?):129046. doi: 10.1016/j.foodchem.2021.129046. [PMID: 33508606]
  • Pascaline Bahati, Xuejun Zeng, Ferdinand Uzizerimana, Ariunsaikhan Tsoggerel, Muhammad Awais, Guo Qi, Rui Cai, Tianli Yue, Yahong Yuan. Adsorption Mechanism of Patulin from Apple Juice by Inactivated Lactic Acid Bacteria Isolated from Kefir Grains. Toxins. 2021 06; 13(7):. doi: 10.3390/toxins13070434. [PMID: 34206488]
  • Laura Settier-Ramírez, Gracia López-Carballo, Pilar Hernández-Muñoz, Angélique Fontana, Caroline Strub, Sabine Schorr-Galindo. New Isolated Metschnikowia pulcherrima Strains from Apples for Postharvest Biocontrol of Penicillium expansum and Patulin Accumulation. Toxins. 2021 06; 13(6):. doi: 10.3390/toxins13060397. [PMID: 34199507]
  • Xiaoyun Liu, Xiaomin Cui, Dongchao Ji, Zhanquan Zhang, Boqiang Li, Yong Xu, Tong Chen, Shiping Tian. Luteolin-induced activation of the phenylpropanoid metabolic pathway contributes to quality maintenance and disease resistance of sweet cherry. Food chemistry. 2021 Apr; 342(?):128309. doi: 10.1016/j.foodchem.2020.128309. [PMID: 33051099]
  • Jiahui Han, Chengni Jin, Yujie Zhong, Jiachang Zhu, Qi Liu, Dianjun Sun, Jiayu Feng, Xiaodong Xia, Xiaoli Peng. Involvement of NADPH oxidase in patulin-induced oxidative damage and cytotoxicity in HEK293 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2021 Apr; 150(?):112055. doi: 10.1016/j.fct.2021.112055. [PMID: 33577942]
  • Jinling Cui, Shutao Yin, Chong Zhao, Lihong Fan, Hongbo Hu. Combining Patulin with Cadmium Induces Enhanced Hepatotoxicity and Nephrotoxicity In Vitro and In Vivo. Toxins. 2021 03; 13(3):. doi: 10.3390/toxins13030221. [PMID: 33803748]
  • Hongyin Zhang, Joseph Ahima, Qiya Yang, Lina Zhao, Xiaoyun Zhang, Xiangfeng Zheng. A review on citrinin: Its occurrence, risk implications, analytical techniques, biosynthesis, physiochemical properties and control. Food research international (Ottawa, Ont.). 2021 03; 141(?):110075. doi: 10.1016/j.foodres.2020.110075. [PMID: 33641962]
  • Jiang He, Natasha Marie Evans, Huaizhi Liu, Yan Zhu, Ting Zhou, Suqin Shao. UV treatment for degradation of chemical contaminants in food: A review. Comprehensive reviews in food science and food safety. 2021 03; 20(2):1857-1886. doi: 10.1111/1541-4337.12698. [PMID: 33486857]
  • Yashodani Pillay, Terisha Ghazi, Shanel Raghubeer, Savania Nagiah, Anil A Chuturgoon. Patulin activates the NRF2 pathway by modulation of miR-144 expression in HEK293 cells. Mycotoxin research. 2021 Feb; 37(1):97-103. doi: 10.1007/s12550-020-00418-4. [PMID: 33403569]
  • Vincenzo Tragni, Pietro Cotugno, Anna De Grassi, Federica Massari, Francesco Di Ronzo, Antonella Maria Aresta, Carlo Zambonin, Simona Marianna Sanzani, Antonio Ippolito, Ciro Leonardo Pierri. Targeting mitochondrial metabolite transporters in Penicillium expansum for reducing patulin production. Plant physiology and biochemistry : PPB. 2021 Jan; 158(?):158-181. doi: 10.1016/j.plaphy.2020.07.027. [PMID: 33250320]
  • Chaozhi Wei, Leilei Yu, Nanzhen Qiao, Shumin Wang, Fengwei Tian, Jianxin Zhao, Hao Zhang, Qixiao Zhai, Wei Chen. The characteristics of patulin detoxification by Lactobacillus plantarum 13M5. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2020 Dec; 146(?):111787. doi: 10.1016/j.fct.2020.111787. [PMID: 33031840]
  • Yashodani Pillay, Savania Nagiah, Alisa Phulukdaree, Anand Krishnan, Anil A Chuturgoon. Patulin suppresses α1-adrenergic receptor expression in HEK293 cells. Scientific reports. 2020 11; 10(1):20115. doi: 10.1038/s41598-020-77157-0. [PMID: 33208818]
  • Dianiris Luciano-Rosario, Nancy P Keller, Wayne M Jurick. Penicillium expansum: biology, omics, and management tools for a global postharvest pathogen causing blue mould of pome fruit. Molecular plant pathology. 2020 11; 21(11):1391-1404. doi: 10.1111/mpp.12990. [PMID: 32969130]
  • Boqiang Li, Yong Chen, Zhanquan Zhang, Guozheng Qin, Tong Chen, Shiping Tian. Molecular basis and regulation of pathogenicity and patulin biosynthesis in Penicillium expansum. Comprehensive reviews in food science and food safety. 2020 11; 19(6):3416-3438. doi: 10.1111/1541-4337.12612. [PMID: 33337032]
  • Nianfa Han, Ruilin Luo, Jiayu Liu, Tianmin Guo, Jiayu Feng, Xiaoli Peng. Transcriptomic and Proteomic Analysis Reveals Mechanisms of Patulin-Induced Cell Toxicity in Human Embryonic Kidney Cells. Toxins. 2020 10; 12(11):. doi: 10.3390/toxins12110681. [PMID: 33138038]
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