Quercimeritrin (BioDeep_00000019579)

Main id: BioDeep_00000009367

 

human metabolite PANOMIX_OTCML-2023 natural product


代谢物信息卡片


Quercetin 7-O-beta-D-glucoside

化学式: C21H20O12 (464.0955)
中文名称: 槲皮素-7-O-β-D-葡萄糖苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c1(cc(c2c(c1)oc(c(c2=O)O)c1ccc(c(c1)O)O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
InChI: InChI=1S/C21H20O12/c22-6-13-15(26)17(28)19(30)21(33-13)31-8-4-11(25)14-12(5-8)32-20(18(29)16(14)27)7-1-2-9(23)10(24)3-7/h1-5,13,15,17,19,21-26,28-30H,6H2/t13-,15-,17+,19-,21-/m1/s1

描述信息

Quercimeritrin, isolated from the leaves of Ixeridium dentatum, exhibits significant amylase activity[1].
Quercimeritrin, isolated from the leaves of Ixeridium dentatum, exhibits significant amylase activity[1].

同义名列表

7 个代谢物同义名

Quercetin 7-O-beta-D-glucoside; quercetin-7-O-glucoside; Quercetin-O-glucoside; Quercetin 7-glucoside; Quercimeritrin; Quercetin-7-O-β-D-glucopyranoside; Quercimeritrin



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

721 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ACE, CASP1, EGFR, GSTP1, HIF1A, MAPK8, NLRP3, PTGS2, TYR
Peripheral membrane protein 2 ACHE, PTGS2
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 2 EGFR, PTGS2
Nucleus 9 ACHE, AURKA, EGFR, GSTP1, HIF1A, KDR, MAPK8, NCOA1, NLRP3
cytosol 7 AURKA, CASP1, GSTP1, HIF1A, MAPK8, NCOA1, NLRP3
nuclear body 1 HIF1A
centrosome 1 AURKA
nucleoplasm 5 AURKA, HIF1A, MAPK8, MRPL58, NCOA1
RNA polymerase II transcription regulator complex 2 HIF1A, NCOA1
Cell membrane 7 ACE, ACHE, ADRB3, CASP1, EGFR, KDR, KIT
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Multi-pass membrane protein 1 ADRB3
Golgi apparatus membrane 1 NLRP3
Synapse 2 ACHE, MAPK8
cell junction 2 EGFR, KDR
cell surface 2 ACHE, EGFR
glutamatergic synapse 2 AURKA, EGFR
Golgi apparatus 2 ACHE, KDR
Golgi membrane 2 EGFR, NLRP3
lysosomal membrane 1 GAA
mitochondrial inner membrane 1 MRPL58
neuromuscular junction 1 ACHE
Cytoplasm, cytosol 1 NLRP3
Lysosome 3 ACE, GAA, TYR
acrosomal vesicle 1 KIT
endosome 3 ACE, EGFR, KDR
plasma membrane 12 ACE, ACHE, ADRB3, BCHE, CASP1, CSF2, EGFR, GAA, KDR, KIT, MRPL58, NCOA1
Membrane 6 ACE, ACHE, EGFR, GAA, KIT, NLRP3
apical plasma membrane 1 EGFR
axon 1 MAPK8
basolateral plasma membrane 2 AURKA, EGFR
caveola 1 PTGS2
extracellular exosome 3 ACE, GAA, GSTP1
Lysosome membrane 1 GAA
endoplasmic reticulum 3 KDR, NLRP3, PTGS2
extracellular space 8 ACE, ACHE, BCHE, CSF2, CXCL8, EGFR, GSTP1, KIT
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 4 ACHE, AURKA, EGFR, TYR
mitochondrion 3 GSTP1, MRPL58, NLRP3
protein-containing complex 5 CASP1, EGFR, HIF1A, NCOA1, PTGS2
intracellular membrane-bounded organelle 3 CSF2, GAA, TYR
Microsome membrane 1 PTGS2
postsynaptic density 1 AURKA
pronucleus 1 AURKA
Single-pass type I membrane protein 4 ACE, EGFR, KIT, TYR
Secreted 7 ACE, ACHE, BCHE, CSF2, CXCL8, GAA, NLRP3
extracellular region 9 ACE, ACHE, BCHE, CSF2, CXCL8, GAA, GSTP1, KDR, NLRP3
cytoplasmic side of plasma membrane 1 KIT
[Isoform 2]: Secreted 1 KDR
mitochondrial matrix 1 MRPL58
Extracellular side 1 ACHE
anchoring junction 1 KDR
transcription regulator complex 1 NCOA1
Cell projection, cilium 1 AURKA
motile cilium 1 HIF1A
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 AURKA
nuclear membrane 1 EGFR
external side of plasma membrane 3 ACE, KDR, KIT
microtubule cytoskeleton 1 AURKA
nucleolus 1 CASP1
axon cytoplasm 1 HIF1A
Melanosome membrane 1 TYR
midbody 1 AURKA
Early endosome 1 KDR
cell-cell junction 1 KIT
Golgi-associated vesicle 1 TYR
spindle midzone 1 AURKA
vesicle 1 GSTP1
Membrane raft 2 EGFR, KDR
Cytoplasm, cytoskeleton, spindle 1 AURKA
focal adhesion 1 EGFR
microtubule 2 AURKA, CASP1
spindle 1 AURKA
basement membrane 1 ACHE
intracellular vesicle 1 EGFR
nuclear speck 1 HIF1A
Cytoplasm, cytoskeleton, microtubule organizing center 1 NLRP3
Inflammasome 1 NLRP3
interphase microtubule organizing center 1 NLRP3
NLRP3 inflammasome complex 2 CASP1, NLRP3
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
receptor complex 4 ADRB3, EGFR, KDR, KIT
Cell projection, neuron projection 1 AURKA
neuron projection 2 AURKA, PTGS2
ciliary basal body 1 AURKA
cilium 1 AURKA
chromatin 2 HIF1A, NCOA1
mitotic spindle 1 AURKA
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole 1 AURKA
Cytoplasm, cytoskeleton, cilium basal body 1 AURKA
centriole 1 AURKA
brush border membrane 1 ACE
blood microparticle 1 BCHE
sperm midpiece 1 ACE
Basolateral cell membrane 1 AURKA
Lipid-anchor, GPI-anchor 1 ACHE
Cytoplasm, cytoskeleton, spindle pole 1 AURKA
fibrillar center 1 KIT
Endomembrane system 1 NLRP3
sorting endosome 1 KDR
microtubule organizing center 1 NLRP3
tertiary granule membrane 1 GAA
Melanosome 1 TYR
Nucleus speckle 1 HIF1A
euchromatin 1 HIF1A
side of membrane 1 ACHE
basal plasma membrane 2 ACE, EGFR
[Isoform 3]: Cytoplasm 1 KIT
synaptic membrane 1 EGFR
ficolin-1-rich granule lumen 1 GSTP1
secretory granule lumen 1 GSTP1
endoplasmic reticulum lumen 2 BCHE, PTGS2
kinetochore 1 AURKA
mitotic spindle pole 1 AURKA
azurophil granule membrane 1 GAA
nuclear envelope lumen 1 BCHE
AIM2 inflammasome complex 1 CASP1
clathrin-coated endocytic vesicle membrane 1 EGFR
axon hillock 1 AURKA
chromosome passenger complex 1 AURKA
germinal vesicle 1 AURKA
meiotic spindle 1 AURKA
spindle pole centrosome 1 AURKA
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 GAA
basal dendrite 1 MAPK8
canonical inflammasome complex 1 CASP1
granulocyte macrophage colony-stimulating factor receptor complex 1 CSF2
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
ribosome 1 MRPL58
TRAF2-GSTP1 complex 1 GSTP1
autolysosome lumen 1 GAA
[Angiotensin-converting enzyme, soluble form]: Secreted 1 ACE
[Isoform Testis-specific]: Cell membrane 1 ACE
[Isoform H]: Cell membrane 1 ACHE
IPAF inflammasome complex 1 CASP1
NLRP1 inflammasome complex 1 CASP1
protease inhibitor complex 1 CASP1
mitochondrial large ribosomal subunit 1 MRPL58


文献列表

  • SeonJu Park, Nguyen Xuan Nhiem, Jun Hyung Park, Kashi Raj Bhattarai, Han-Jung Chae, Hyung-Ryong Kim, Seung Hyun Kim. Isolation of amylase regulators from the leaves of Ixeridium dentatum. Natural product research. 2021 Mar; 35(5):744-749. doi: 10.1080/14786419.2019.1599885. [PMID: 30966790]
  • Enkhtaivan Gansukh, Zakayo Kazibwe, Muthuraman Pandurangan, Gopal Judy, Doo Hwan Kim. Probing the impact of quercetin-7-O-glucoside on influenza virus replication influence. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2016 Aug; 23(9):958-67. doi: 10.1016/j.phymed.2016.06.001. [PMID: 27387404]
  • Bui Thi Thuy Luyen, Bui Huu Tai, Nguyen Phuong Thao, Ji Yun Cha, Hoon Yeon Lee, Young Mi Lee, Young Ho Kim. Anti-inflammatory components of Chrysanthemum indicum flowers. Bioorganic & medicinal chemistry letters. 2015 Jan; 25(2):266-9. doi: 10.1016/j.bmcl.2014.11.054. [PMID: 25497988]
  • Filis Morina, Umeo Takahama, Ryo Yamauchi, Sachiko Hirota, Sonja Veljovic-Jovanovic. Quercetin 7-O-glucoside suppresses nitrite-induced formation of dinitrosocatechins and their quinones in catechin/nitrite systems under stomach simulating conditions. Food & function. 2015 Jan; 6(1):219-29. doi: 10.1039/c4fo00695j. [PMID: 25375233]
  • Tian-Tian Zhang, Chuan-Li Lu, Jian-Guo Jiang. Bioactivity evaluation of ingredients identified from the fruits of Amomum tsaoko Crevost et Lemaire, a Chinese spice. Food & function. 2014 Aug; 5(8):1747-54. doi: 10.1039/c4fo00169a. [PMID: 24915829]
  • Tamara R Calvo, Diego Demarco, Fabio V Santos, Helen P Moraes, Taís M Bauab, Eliana A Varanda, Ilce M S Cólus, Wagner Vilegas. Phenolic compounds in leaves of Alchornea triplinervia: anatomical localization, mutagenicity, and antibacterial activity. Natural product communications. 2010 Aug; 5(8):1225-32. doi: . [PMID: 20839624]
  • Deepak Kumar Semwal, Usha Rawat, Ravindra Semwal, Randhir Singh, Pawan Krishan, Manjeet Singh, Gur Jas Preet Singh. Chemical constituents from the leaves of Boehmeria rugulosa with antidiabetic and antimicrobial activities. Journal of Asian natural products research. 2009 Dec; 11(12):1045-55. doi: 10.1080/10286020903352526. [PMID: 20183275]
  • Young Jae Lee, Sungun Kim, Seung Jae Lee, Inhye Ham, Wan Kyunn Whang. Antioxidant activities of new flavonoids from Cudrania tricuspidata root bark. Archives of pharmacal research. 2009 Feb; 32(2):195-200. doi: 10.1007/s12272-009-1135-z. [PMID: 19280148]
  • Wei-li Han, Li Liu, Xiao-qi Zhang, Wen-cai Ye, Yi-le Pan, Xin-sheng Yao. [Chemical constituents from leaves of Morus multicaulis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2007 Apr; 32(8):695-8. doi: . [PMID: 17608222]
  • M G de Carvalho, D C Cranchi, D G Kingston, A A Werle. Proposed active constituents of Dipladenia martiana. Phytotherapy research : PTR. 2001 Dec; 15(8):715-7. doi: 10.1002/ptr.865. [PMID: 11746866]
  • E Luiz da Silva, T Tsushida, J Terao. Inhibition of mammalian 15-lipoxygenase-dependent lipid peroxidation in low-density lipoprotein by quercetin and quercetin monoglucosides. Archives of biochemistry and biophysics. 1998 Jan; 349(2):313-20. doi: 10.1006/abbi.1997.0455. [PMID: 9448720]
  • N Mahmood, S Piacente, C Pizza, A Burke, A I Khan, A J Hay. The anti-HIV activity and mechanisms of action of pure compounds isolated from Rosa damascena. Biochemical and biophysical research communications. 1996 Dec; 229(1):73-9. doi: 10.1006/bbrc.1996.1759. [PMID: 8954085]