Isoquercitrin (BioDeep_00000000179)

 

Secondary id: BioDeep_00000270288, BioDeep_00000275350, BioDeep_00000337862, BioDeep_00000408302, BioDeep_00000894603

natural product human metabolite PANOMIX_OTCML-2023 blood metabolite Chemicals and Drugs PANOMIX-Anthocyanidin BioNovoGene_Lab2019


代谢物信息卡片


2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

化学式: C21H20O12 (464.0955)
中文名称: 槲皮素 3-β-D-葡萄糖甙, 槲皮素-3-葡萄糖苷, 异槲皮苷, 异懈皮苷, 槲皮素-3-O-葡萄糖苷, 槲皮素-3-β-D-葡萄糖苷、异槲皮苷
谱图信息: 最多检出来源 Viridiplantae(plant) 32.7%

Reviewed

Last reviewed on 2024-07-09.

Cite this Page

Isoquercitrin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/isoquercitrin (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000000179). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: c1(cc(c2c(c1)oc(c(c2=O)O[C@H]1[C@@H]([C@@H]([C@@H]([C@H](O1)CO)O)O)O)c1ccc(c(c1)O)O)O)O
InChI: InChI=1/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15-,17+,18-,21+/m1/s1

描述信息

Quercetin 3-O-beta-D-glucopyranoside is a quercetin O-glucoside that is quercetin with a beta-D-glucosyl residue attached at position 3. Isolated from Lepisorus contortus, it exhibits antineoplastic activityand has been found to decrease the rate of polymerization and sickling of red blood cells It has a role as an antineoplastic agent, a plant metabolite, a bone density conservation agent, an osteogenesis regulator, an antioxidant, a histamine antagonist, an antipruritic drug and a geroprotector. It is a quercetin O-glucoside, a tetrahydroxyflavone, a beta-D-glucoside and a monosaccharide derivative. It is functionally related to a beta-D-glucose. It is a conjugate acid of a quercetin 3-O-beta-D-glucopyranoside(1-).
Isoquercetin has been used in trials studying the treatment of Kidney Cancer, Renal cell carcinoma, Advanced Renal Cell Carcinoma, Thromboembolism of Vein in Pancreatic Cancer, and Thromboembolism of Vein VTE in Colorectal Cancer, among others.
Isoquercitrin is a natural product found in Ficus auriculata, Lotus ucrainicus, and other organisms with data available.
Isoquercetin is an orally bioavailable, glucoside derivative of the flavonoid quercetin and protein disulfide isomerase (PDI) inhibitor, with antioxidant and potential antithrombotic activity. As an antioxidant, isoquercetin scavenges free radicals and inhibits oxidative damage to cells. As a PDI inhibitor, this agent blocks PDI-mediated platelet activation, and fibrin generation, which prevents thrombus formation after vascular injury. In addition, isoquercetin is an alpha-glucosidase inhibitor. PDI, an oxidoreductase secreted by activated endothelial cells and platelets, plays a key role in the initiation of the coagulation cascade. Cancer, in addition to other thrombotic disorders, increases the risk of thrombus formation.

Isoquercitrin is found in alcoholic beverages. Isoquercitrin occurs widely in plants. Isoquercitrin is present in red wine.Isoquercitin can be isolated from mangoes and from Rheum nobile, the Noble rhubarb or Sikkim rhubarb, a giant herbaceous plant native to the Himalaya. Quercetin glycosides are also present in tea. (Wikipedia
A quercetin O-glucoside that is quercetin with a beta-D-glucosyl residue attached at position 3. Isolated from Lepisorus contortus, it exhibits antineoplastic activityand has been found to decrease the rate of polymerization and sickling of red blood cells

[Raw Data] CB053_Isoquercitrin_pos_10eV_CB000025.txt
[Raw Data] CB053_Isoquercitrin_pos_30eV_CB000025.txt
[Raw Data] CB053_Isoquercitrin_pos_50eV_CB000025.txt
[Raw Data] CB053_Isoquercitrin_pos_40eV_CB000025.txt
[Raw Data] CB053_Isoquercitrin_pos_20eV_CB000025.txt
[Raw Data] CB053_Isoquercitrin_neg_40eV_000017.txt
[Raw Data] CB053_Isoquercitrin_neg_20eV_000017.txt
[Raw Data] CB053_Isoquercitrin_neg_50eV_000017.txt
[Raw Data] CB053_Isoquercitrin_neg_30eV_000017.txt
[Raw Data] CB053_Isoquercitrin_neg_10eV_000017.txt

Quercetin 3-glucoside. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=482-35-9 (retrieved 2024-07-09) (CAS RN: 482-35-9). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway[1]. Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies[2].
Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway[1]. Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies[2].
Isoquercitrin (Isoquercitroside) is an effective antioxidant and an eosinophilic inflammation suppressor.
Isoquercitrin (Isoquercitroside) is an effective antioxidant and an eosinophilic inflammation suppressor.

同义名列表

123 个代谢物同义名

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-one; 2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-(3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-chromen-4-one; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxy-phenyl)-3-(.beta.-D-glucofuranosyloxy)-5,7-dihydroxy-; 4H-1-BENZOPYRAN-4-ONE, 2-(3,4-DIHYDROXYPHENYL)-3-(.BETA.-D-GLUCOPYRANOSYLOXY)-5,7-DIHYDROXY-; 2-(3,4-Dihydroxyphenyl)-3-(b-D-glucopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one, 9CI; 4H-1-BENZOPYRAN-4-ONE, 2- (3,4-DIHYDROXYPHENYL)-3- (SS-D-GLUCOFURANOSYLOXY)-5,7-DIHYDROXY-; 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(beta-D-glucopyranosyloxy)-5,7-dihydroxy-; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(3,4-dihydroxyphenyl)-3-(beta-D-glucopyranosyloxy)-; 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(beta-D-glucofuranosyloxy)-5,7-dihydroxy; 2-(3,4-Dihidroxyphenyl)-3-(beta-D-glucofuranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one; 4H-1-BENZOPYRAN-4-ONE, 2-(3,4-DIHYDROXYPHENYL)-3-(SS-D-GLUCOFURANOSYLOXY)-5,7-DIHYDROXY-; 2-(3,4-dihydroxyphenyl)-3-(beta-D-glucopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one; 2-(3,4-dihydroxyphenyl)-3-(beta-D-glucofuranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-3-(b-D-glucopyranosyloxy)-5,7-dihydroxy-; 2-(3,4-Dihidroxyphenyl)-3-(β-D-glucofuranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one; 2-(3,4-Dihydroxyphenyl)-3-(b-D-glucopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one; 2-(3,4-Dihydroxyphenyl)-3-(β-D-glucopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one; 2-(3,4-Dihidroxyphenyl)-3-(b-D-glucofuranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl beta-D-glucopyranoside; flavone, 3,3,4,5,7-pentahydroxy-, 3-beta-D-glucofuranoside; Isoquercitrin, primary pharmaceutical reference standard; 3,4,5,7-TETRAHYDROXYFLAVONE-3-.BETA.-D-GLUCOPYRANOSIDE; QUERCETIN 3-O-GLUCOSIDE (CONSTITUENT OF GINKGO) [DSC]; 3,4,5,7-TETRAHYDROXYFLAVONE-3-beta-D-GLUCOPYRANOSIDE; 3’,4’,5,7-Tetrahydroxyflavone-3-β-D-glucopyranoside; 3,4,5,7-Tetrahydroxyflavone-3-β-D-glucopyranoside; 3,3,4,5,7-pentahydroxyflavone-3-beta-O-glucoside; QUERCETIN 3-O-GLUCOSIDE (CONSTITUENT OF GINKGO); 3-Glucopyranosyloxy-3,4,5,7-tetrahydroxyflavone; 3,3,4,5,7-Pentahydroxyflavone 3-beta-glucoside; 4-18-00-03493 (Beilstein Handbook Reference); Quercetin 3-beta-D-glucoside, >=90\\% (HPLC); 3,3,4,5,7-Pentahydroxyflavone 3-A-glucoside; Quercetin 3-glucoside, analytical standard; (-)-Quercetin-3-O-beta-D-glucopyranoside; quercetin -3-O-beta-D-galactopyranoside; QUERCETIN 3-O-GLUCOPYRANOSIDE [WHO-DD]; Quercetin-3-O-beta-D-galactopyranoside; Quercetin 3-O-.beta.-D-glucopyranoside; quercetin-3-O-beta-D-glucopyranoside; quercetin 3-(beta-D-glucofuranoside); quercetin 3-O-beta-D-glucopyranoside; 3-O-.BETA.-D-GLUCOPYRANOSYLQUERCETIN; quercetin 3-O-beta-D-glucofuranoside; Quercetin 3-beta-D-glucopyranoside; QUERCETIN-3-.BETA.-GLUCOPYRANOSIDE; quercetin-3-o-beta-glucopyranoside; 3-o-beta-d-glucopyranosylquercetin; Quercetin 3-O-β-D-glucopyranoside; Quercetin 3-O-b-D-glucopyranoside; quercetin-3-beta-glucopyranoside; QUERCETIN-3-O-.BETA.-D-GLUCOSIDE; 3-O-β-D-Glucopyranosylquercetin; Quercetin 3-β-D-glucopyranoside; Quercetin 3- beta -D-glucoside; quercetin 3-O-beta-D-glucoside; Quercetin-3-O-glucopyranoside; Quercetin-3-β-glucopyranoside; Quercetin 3-o-glucopyranoside; Quercetin 3-beta-O-glucoside; Quercetin 3-mono-D-glucoside; Quercetin 3-O-beta-glucoside; Quercetin 3-beta-D-glucoside; quercetin-3-O-beta-glucoside; Quercetin 3-O-β-D-glucoside; Quercetin 3beta-O-glucoside; Quercetin 3.beta.-glucoside; Quercetin 3-glucopyranoside; OVSQVDMCBVZWGM-QSOFNFLRSA-N; Quercetin 3-beta-glucoside; Quercetin 3-ss-D-glucoside; 3-beta-D-Glucosylquercetin; QUERCETIN 3beta-GLUCOSIDE; Quercetin 3-β-D-glucoside; Quercetol 3-monoglucoside; Quercetin 3-O-β-glucoside; 3-glucoside isoquercitrin; Quercetin 3-monoglucoside; Quercetin 3β-O-glucoside; Quercetin 3-D-glucoside; Quercetin 3-O-glucoside; quercetin-3-O-glucoside; 3-β-D-Glucosylquercetin; Quercetin 3β-glucoside; Ronacare isoquercetin; Quercetin 3-glucoside; Quercetol 3-glucoside; quercetin-3-glucoside; Glucosyl 3-quercetin; Glucosyl-3-quercetin; Quercetin-3-glucose; ISOQUERCETIN [INCI]; 3-Glucosylquercetin; quercetin glucoside; ISOQUERCITRIN [MI]; Isoquercetin, (-)-; (-)-Isoquercetrin; Isoquercitrin (6); isoquercitroside; UNII-6HN2PC637T; CONTIGOSIDE B; Isoquercetrin; Isoquercitrin; isoquercitin; PDSP1_001363; isotrifoliin; PDSP2_001347; Isoquercetin; ACon1_002134; trifoliin A; 6HN2PC637T; Hirsutrin; hydroside; trifoliin; Q 5; HW2; 2-(3,4-Dihidroxyphenyl)-3-(β-D-glucofuranosyloxy)-5,7-dihydroxy- 4H-1-benzopyran-4-one; Quercetin 3-O-glucoside



数据库引用编号

67 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(1)

PharmGKB(0)

347 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 AKT1, CASP3, CAT, CTNNB1, NFE2L2, PIK3CA, PRKAA2, PTGS2, SYT1, TLR4, TYR
Peripheral membrane protein 1 PTGS2
Endosome membrane 1 TLR4
Endoplasmic reticulum membrane 2 HMOX1, PTGS2
Nucleus 7 AKT1, CASP3, CTNNB1, HMOX1, NFE2L2, PCNA, PRKAA2
cytosol 9 AKT1, CASP3, CAT, CTNNB1, HMOX1, LIPE, NFE2L2, PIK3CA, PRKAA2
dendrite 1 PRKAA2
nuclear body 1 PCNA
centrosome 3 CTNNB1, NFE2L2, PCNA
nucleoplasm 7 AKT1, CASP3, CTNNB1, HMOX1, NFE2L2, PCNA, PRKAA2
RNA polymerase II transcription regulator complex 1 NFE2L2
Cell membrane 6 AKT1, CTNNB1, LIPE, MGAM, TLR4, TNF
Cytoplasmic side 1 HMOX1
lamellipodium 3 AKT1, CTNNB1, PIK3CA
Multi-pass membrane protein 1 SLC5A1
Synapse 2 CTNNB1, SYT1
cell cortex 2 AKT1, CTNNB1
cell junction 1 CTNNB1
cell surface 2 TLR4, TNF
glutamatergic synapse 4 AKT1, CASP3, CTNNB1, SYT1
Golgi apparatus 3 NFE2L2, PRKAA2, SYT1
Golgi membrane 1 INS
neuronal cell body 3 CASP3, PRKAA2, TNF
postsynapse 1 AKT1
presynaptic membrane 2 CTNNB1, SYT1
synaptic vesicle 1 SYT1
Cytoplasm, cytosol 2 LIPE, NFE2L2
Lysosome 1 TYR
plasma membrane 9 AKT1, CTNNB1, MGAM, NFE2L2, PIK3CA, SLC5A1, SYT1, TLR4, TNF
presynaptic active zone 1 SYT1
synaptic vesicle membrane 1 SYT1
Membrane 9 AKT1, CAT, CTNNB1, HMOX1, LIPE, MGAM, PRKAA2, SYT1, TLR4
apical plasma membrane 2 MGAM, SLC5A1
axon 2 PRKAA2, SYT1
basolateral plasma membrane 1 CTNNB1
caveola 2 LIPE, PTGS2
extracellular exosome 6 BMP3, CAT, CTNNB1, MGAM, PCNA, SLC5A1
endoplasmic reticulum 2 HMOX1, PTGS2
extracellular space 5 BMP3, HMOX1, IL6, INS, TNF
perinuclear region of cytoplasm 6 CTNNB1, HMOX1, PIK3CA, SLC5A1, TLR4, TYR
Schaffer collateral - CA1 synapse 1 CTNNB1
adherens junction 1 CTNNB1
apicolateral plasma membrane 1 CTNNB1
bicellular tight junction 1 CTNNB1
intercalated disc 1 PIK3CA
mitochondrion 1 CAT
protein-containing complex 4 AKT1, CAT, CTNNB1, PTGS2
intracellular membrane-bounded organelle 2 CAT, TYR
Microsome membrane 1 PTGS2
postsynaptic density 2 CASP3, SYT1
Single-pass type I membrane protein 2 TLR4, TYR
Secreted 4 BMP3, IL6, INS, MGAM
extracellular region 6 BMP3, CAT, IL6, INS, MGAM, TNF
Single-pass membrane protein 2 MGAM, SYT1
mitochondrial outer membrane 1 HMOX1
excitatory synapse 1 SYT1
hippocampal mossy fiber to CA3 synapse 1 SYT1
mitochondrial matrix 1 CAT
transcription regulator complex 1 CTNNB1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 SYT1
external side of plasma membrane 2 TLR4, TNF
Z disc 1 CTNNB1
beta-catenin destruction complex 1 CTNNB1
microtubule cytoskeleton 1 AKT1
Wnt signalosome 1 CTNNB1
Melanosome membrane 1 TYR
Early endosome 2 SLC5A1, TLR4
apical part of cell 1 CTNNB1
cell-cell junction 2 AKT1, CTNNB1
Golgi-associated vesicle 1 TYR
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
postsynaptic membrane 2 CTNNB1, SYT1
Apical cell membrane 1 SLC5A1
Membrane raft 1 TNF
Cytoplasm, cytoskeleton 1 CTNNB1
focal adhesion 2 CAT, CTNNB1
spindle 1 AKT1
Cell junction, adherens junction 1 CTNNB1
flotillin complex 1 CTNNB1
Peroxisome 1 CAT
intracellular vesicle 1 SLC5A1
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
fascia adherens 1 CTNNB1
lateral plasma membrane 1 CTNNB1
nuclear speck 1 PRKAA2
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 1 TLR4
neuron projection 2 PTGS2, SYT1
ciliary basal body 1 AKT1
chromatin 2 NFE2L2, PCNA
mediator complex 1 NFE2L2
phagocytic cup 2 TLR4, TNF
cell periphery 1 CTNNB1
Cytoplasm, cytoskeleton, cilium basal body 1 CTNNB1
brush border membrane 1 SLC5A1
spindle pole 1 CTNNB1
nuclear replication fork 1 PCNA
chromosome, telomeric region 1 PCNA
postsynaptic density, intracellular component 1 CTNNB1
microvillus membrane 1 CTNNB1
Endomembrane system 2 CTNNB1, SYT1
endosome lumen 1 INS
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
tertiary granule membrane 1 MGAM
Melanosome 1 TYR
cytoplasmic stress granule 1 PRKAA2
euchromatin 1 CTNNB1
replication fork 1 PCNA
exocytic vesicle 1 SYT1
lipopolysaccharide receptor complex 1 TLR4
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 IL6, INS, PTGS2
male germ cell nucleus 1 PCNA
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
dense core granule 1 SYT1
transport vesicle 1 INS
beta-catenin-TCF complex 1 CTNNB1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Single-pass type IV membrane protein 1 HMOX1
presynaptic active zone cytoplasmic component 1 CTNNB1
nuclear lamina 1 PCNA
clathrin-coated endocytic vesicle membrane 1 SYT1
protein-DNA complex 2 CTNNB1, NFE2L2
ficolin-1-rich granule membrane 1 MGAM
death-inducing signaling complex 1 CASP3
Cytoplasmic vesicle, secretory vesicle membrane 1 SYT1
nucleotide-activated protein kinase complex 1 PRKAA2
postsynaptic cytosol 1 SYT1
catenin complex 1 CTNNB1
presynaptic cytosol 1 SYT1
cyclin-dependent protein kinase holoenzyme complex 1 PCNA
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
neuron projection terminus 1 SYT1
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane 1 SYT1
chromaffin granule membrane 1 SYT1
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane 1 SYT1
PCNA complex 1 PCNA
PCNA-p21 complex 1 PCNA
replisome 1 PCNA
intracellular organelle 1 SLC5A1
beta-catenin-TCF7L2 complex 1 CTNNB1
clathrin-sculpted acetylcholine transport vesicle membrane 1 SYT1
clathrin-sculpted glutamate transport vesicle membrane 1 SYT1
clathrin-sculpted monoamine transport vesicle membrane 1 SYT1
beta-catenin-ICAT complex 1 CTNNB1
Scrib-APC-beta-catenin complex 1 CTNNB1
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Qi-Yang Wang, Hao-Yu Wang, Wei-Guo Zhang, Jian-Zhong Xu. Economical one-pot synthesis of isoquercetin and D-allulose from quercetin and sucrose using whole-cell biocatalyst. Enzyme and microbial technology. 2024 May; 176(?):110412. doi: 10.1016/j.enzmictec.2024.110412. [PMID: 38402828]
  • Tengfei Niu, Chaokang Huang, Rufeng Wang, Li Yang, Shujuan Zhao, Zhengtao Wang. Combinatorial metabolic engineering of Bacillus subtilis enables the efficient biosynthesis of isoquercitrin from quercetin. Microbial cell factories. 2024 Apr; 23(1):114. doi: 10.1186/s12934-024-02390-5. [PMID: 38641799]
  • Hong-Liu Jin, Xiao-Ying Feng, Sen-Ling Feng, Ling Dai, Wen-Ting Zhu, Zhong-Wen Yuan. Isoquercitrin attenuates the progression of non-alcoholic steatohepatitis in mice by modulating galectin-3-mediated insulin resistance and lipid metabolism. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jan; 123(?):155188. doi: 10.1016/j.phymed.2023.155188. [PMID: 38056146]
  • Meijuan Yi, Opeyemi B Fasina, Yajing Li, Lan Xiang, Jianhua Qi. Mixture of Peanut Skin Extract, Geniposide, and Isoquercitrin Improves the Hepatic Lipid Accumulation of Mice via Modification of Gut Microbiota Homeostasis and the TLR4 and AMPK Signaling Pathways. International journal of molecular sciences. 2023 Nov; 24(23):. doi: 10.3390/ijms242316684. [PMID: 38069009]
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