linolenate(18:3) (BioDeep_00000000175)

   

human metabolite PANOMIX_OTCML-2023 Exogenous blood metabolite BioNovoGene_Lab2019 natural product


代谢物信息卡片


(9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid

化学式: C18H30O2 (278.2246)
中文名称: α-亚麻酸, 亚麻酸
谱图信息: 最多检出来源 Homo sapiens(blood) 15.07%

Reviewed

Last reviewed on 2024-09-25.

Cite this Page

linolenate(18:3). BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/linolenate(18:3) (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000000175). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(CCCCCCC(=O)O)/C=C\C/C=C\C/C=C\CC
InChI: InChI=1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h3-4,6-7,9-10H,2,5,8,11-17H2,1H3,(H,19,20)/b4-3-,7-6-,10-9-

描述信息

alpha-Linolenic acid (ALA) is a polyunsaturated fatty acid (PUFA). It is a member of the group of essential fatty acids called omega-3 fatty acids. alpha-Linolenic acid, in particular, is not synthesized by mammals and therefore is an essential dietary requirement for all mammals. Certain nuts (English walnuts) and vegetable oils (canola, soybean, flaxseed/linseed, olive) are particularly rich in alpha-linolenic acid. Omega-3 fatty acids get their name based on the location of one of their first double bond. In all omega-3 fatty acids, the first double bond is located between the third and fourth carbon atom counting from the methyl end of the fatty acid (n-3). Although humans and other mammals can synthesize saturated and some monounsaturated fatty acids from carbon groups in carbohydrates and proteins, they lack the enzymes necessary to insert a cis double bond at the n-6 or the n-3 position of a fatty acid. Omega-3 fatty acids like alpha-linolenic acid are important structural components of cell membranes. When incorporated into phospholipids, they affect cell membrane properties such as fluidity, flexibility, permeability, and the activity of membrane-bound enzymes. Omega-3 fatty acids can modulate the expression of a number of genes, including those involved with fatty acid metabolism and inflammation. alpha-Linolenic acid and other omega-3 fatty acids may regulate gene expression by interacting with specific transcription factors, including peroxisome proliferator-activated receptors (PPARs) and liver X receptors (LXRs). alpha-Linolenic acid is found to be associated with isovaleric acidemia, which is an inborn error of metabolism.

α-Linolenic acid can be obtained by humans only through their diets. Humans lack the desaturase enzymes required for processing stearic acid into A-linoleic acid or other unsaturated fatty acids.

Dietary α-linolenic acid is metabolized to stearidonic acid, a precursor to a collection of polyunsaturated 20-, 22-, 24-, etc fatty acids (eicosatetraenoic acid, eicosapentaenoic acid, docosapentaenoic acid, tetracosapentaenoic acid, 6,9,12,15,18,21-tetracosahexaenoic acid, docosahexaenoic acid).[12] Because the efficacy of n−3 long-chain polyunsaturated fatty acid (LC-PUFA) synthesis decreases down the cascade of α-linolenic acid conversion, DHA synthesis from α-linolenic acid is even more restricted than that of EPA.[13] Conversion of ALA to DHA is higher in women than in men.[14]

α-Linolenic acid, also known as alpha-linolenic acid (ALA) (from Greek alpha meaning "first" and linon meaning flax), is an n−3, or omega-3, essential fatty acid. ALA is found in many seeds and oils, including flaxseed, walnuts, chia, hemp, and many common vegetable oils.

In terms of its structure, it is named all-cis-9,12,15-octadecatrienoic acid.[2] In physiological literature, it is listed by its lipid number, 18:3 (n−3). It is a carboxylic acid with an 18-carbon chain and three cis double bonds. The first double bond is located at the third carbon from the methyl end of the fatty acid chain, known as the n end. Thus, α-linolenic acid is a polyunsaturated n−3 (omega-3) fatty acid. It is a regioisomer of gamma-linolenic acid (GLA), an 18:3 (n−6) fatty acid (i.e., a polyunsaturated omega-6 fatty acid with three double bonds).

Alpha-linolenic acid is a linolenic acid with cis-double bonds at positions 9, 12 and 15. Shown to have an antithrombotic effect. It has a role as a micronutrient, a nutraceutical and a mouse metabolite. It is an omega-3 fatty acid and a linolenic acid. It is a conjugate acid of an alpha-linolenate and a (9Z,12Z,15Z)-octadeca-9,12,15-trienoate.
Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
alpha-Linolenic acid is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Linolenic Acid is a natural product found in Prunus mume, Dipteryx lacunifera, and other organisms with data available.
Linolenic Acid is an essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis of prostaglandin resulting in reduced inflammation and prevention of certain chronic diseases.
Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
A fatty acid that is found in plants and involved in the formation of prostaglandins.

Seed oils are the richest sources of α-linolenic acid, notably those of hempseed, chia, perilla, flaxseed (linseed oil), rapeseed (canola), and soybeans. α-Linolenic acid is also obtained from the thylakoid membranes in the leaves of Pisum sativum (pea leaves).[3] Plant chloroplasts consisting of more than 95 percent of photosynthetic thylakoid membranes are highly fluid due to the large abundance of ALA, evident as sharp resonances in high-resolution carbon-13 NMR spectra.[4] Some studies state that ALA remains stable during processing and cooking.[5] However, other studies state that ALA might not be suitable for baking as it will polymerize with itself, a feature exploited in paint with transition metal catalysts. Some ALA may also oxidize at baking temperatures.
Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease[1].
Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease[1].
α-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].
α-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].
α-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

同义名列表

137 个代谢物同义名

alpha-Linolenic acid, 1.0 mg/mL in ethanol, certified reference material; alpha-LINOLENIC ACID (C18:3) (CONSTITUENT OF KRILL OIL); LINOLENIC ACID (CONSTITUENT OF EVENING PRIMROSE OIL); alpha-Linolenic acid; ALA; cis-alpha-Linolenic acid; alpha-LINOLENIC ACID (CONSTITUENT OF FLAX SEED OIL); 9,12,15-Octadecatrienoic acid, (9Z,12Z,15Z)- (9CI); LINOLENIC ACID (CONSTITUENT OF SAW PALMETTO) [DSC]; Linolenic acid, Vetec(TM) reagent grade, 98\\%; LINOLENIC ACID (CONSTITUENT OF SAW PALMETTO); 9,12,15-Octadecatrienoic acid, (9Z,12Z,15Z)-; cis-9, cis-12, cis-15-octadecatrienoic acid; (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid; (9Z,12Z,15Z)-9,12,15-Octadecatrienoic acid; (9Z,12Z,15Z)octadeca-9,12,15-trienoic acid; cis,cis,cis-octadeca-9,12,15-trienoic acid; cis-9,cis-12,cis-15-Octadecatrienoic acid; 9-cis,12-cis,15-cis-Octadecatrienoic acid; cis,cis,cis-9,12,15-Octadecatrienoic acid; VITAMIN F COMPONENT ALPHA LINOLENIC ACID; cis-Delta(9,12,15)-octadecatrienoic acid; CIS-DELTA-9,12,15-OCTADECATRIENOIC ACID; Linolenic acid 10 microg/mL in Methanol; 9,12,15-Octadecatrienoic acid, (Z,Z,Z)-; Octadecatrienoic acid, 9,12,15-(Z,Z,Z)-; cis-delta9,12,15-Octadecatrienoic acid; 9(Z),12(Z),15(Z)-Octadecatrienoic acid; (Z,Z,Z)-Octadeca-9,12,15-trienoic acid; 9,12,15-all-cis-Octadecatrienoic acid; 9-cis,12-cis,15-cis-octadecatrienoate; (Z,Z,Z)-9,12,15-Octadecatrienoic acid; all-cis-9,12,15-Octadecatrienoic acid; cis,cis,cis-9,12,15-octadecatrienoate; (all-Z)-9,12,15-Octadecatrienoic acid; cis,cis-9,12,15-Octadecatrienoic acid; alpha-Linolenic Acid, (E,E,Z)-Isomer; alpha-Linolenic Acid, Potassium Salt; alpha Linolenic Acid, Magnesium Salt; alpha-Linolenic Acid, (E,Z,Z)-Isomer; alpha-Linolenic Acid, (E,Z,E)-Isomer; alpha-Linolenic Acid, Magnesium Salt; 9,15-Octadecatrienoic acid, (Z,Z,Z)-; cis-Δ(9,12,15)-octadecatrienoic acid; alpha-Linolenic Acid, (E,E,E)-Isomer; cis-delta(9,12,15)-Octadecatrienoate; alpha-Linolenic Acid, (Z,Z,E)-Isomer; alpha-Linolenic Acid, (Z,E,Z)-Isomer; alpha Linolenic Acid, Potassium Salt; 2DCD0473-E5CC-47BB-A0A4-95899AFF6C4B; alpha-Linolenic Acid, (Z,E,E)-Isomer; Linolenic acid, analytical standard; alpha-Linolenic Acid, Ammonium Salt; alpha Linolenic Acid, Ammonium Salt; (9Z,12Z,15Z)-Octadecatrienoic acid; all-cis-9,15-Octadecatrienoic acid; alpha-Linolenic Acid, Calcium Salt; alpha-Linolenic Acid, Tin(2+) Salt; alpha-Linolenic Acid, Lithium Salt; alpha Linolenic Acid, Calcium Salt; alpha Linolenic Acid, Lithium Salt; all-cis-9,12,15-Octadecatrienoate; Fatty Acid cis, cis, cis 18:3 n-3; cis-9,12,15-octadecatrienoic acid; (Z,Z,Z)-9,12,15-Octadecatrienoate; Octadeca-9Z,12Z,15Z-trienoic acid; alpha-Linolenic Acid, Sodium Salt; alpha Linolenic Acid, Sodium Salt; 9Z,12Z,15Z-Octadecatrienoic acid; cis-Δ(9,12,15)-octadecatrienoate; alpha Linolenic Acid, Zinc Salt; alpha-Linolenic Acid, Zinc Salt; ALPHA-LINOLENIC ACID (C18:3 N3); (9Z,12Z,15Z)-Octadecatrienoate; cis-9,12,15-octadecatrienoate; 9,12,15-Octadecatrienoic acid; Linolenic acid, tech grade; Linolenic acid, ~70\\% (GC); alpha-Linolenic Acid tech.; 9,12,15-Octadecatrienoate; LINOLENIC ACID (18:3 n-3); (9,12,15)-linolenic acid; LINOLENIC ACID [WHO-DD]; LINOLENIC ACID [VANDF]; Linolenic acid, >=99\\%; LINOLENIC ACID [MART.]; LINOLENIC ACID (MART.); .alpha.-Linolenic acid; Linolenic acid, crude; alpha -linolenic acid; LINOLENIC ACID [INCI]; alpha-Linolenic acid; alpha Linolenic Acid; alpha-linolenic-acid; FA(18:3(9Z,12Z,15Z)); (9,12,15)-Linolenate; Linolenic acid (8CI); LINOLENIC ACID [MI]; alpha-Linolenate; a-Linolenic acid; α linolenic acid; α-Linolenic acid; UNII-0RBV727H71; Industrene 120; Linolenic Acid; Linolensaeure; Tox21_201727; Α-linolenate; Tox21_303322; a-Linolenate; C18:3n-3,6,9; Tox21_111071; IDI1_033846; α-Linolenic; C18:3 (N-3); 0RBV727H71; linolenate; FA(18:3n3); alpha-Lnn; 18:3(N-3); AI3-23986; alpha-LA; C18H30O2; BML3-B05; FA 18:3; C18:3; LNL; Ala; trans-9, trans-12, trans-15-octadecatrienoic acid; 9E,12E,15E-octadecatrienoic acid; α-Linolenic Acid; Elaidolinoleic acid; α-Linolenate; ?-linolenic acid; Alpha-Linolenic Acid; γ-Linolenic acid; Gamma-Linolenic acid; (9Z,12Z,15Z)-Octadecatrienoic acid; Linolenic acid



数据库引用编号

37 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(5)

BioCyc(0)

PlantCyc(0)

代谢反应

863 个相关的代谢反应过程信息。

Reactome(70)

BioCyc(0)

WikiPathways(4)

Plant Reactome(384)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(405)

PharmGKB(0)

1265 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 APOB, APOE, BDNF, FASN, NOS2, PIK3CA, PTGS2
Peripheral membrane protein 2 ACHE, PTGS2
Endosome membrane 2 APOB, FFAR4
Endoplasmic reticulum membrane 5 APOB, FADS1, FADS2, HSP90B1, PTGS2
Nucleus 5 ACHE, APOE, HSP90B1, NOS2, PPARA
cytosol 6 APOB, FASN, HSP90B1, LEP, NOS2, PIK3CA
dendrite 2 APOE, BDNF
nucleoplasm 2 NOS2, PPARA
Cell membrane 2 ACHE, FFAR4
lamellipodium 1 PIK3CA
Multi-pass membrane protein 4 CPT1A, FADS1, FADS2, FFAR4
Synapse 1 ACHE
cell surface 2 ACHE, ADIPOQ
glutamatergic synapse 1 APOE
Golgi apparatus 3 ACHE, APOE, FASN
lysosomal membrane 1 FFAR4
neuromuscular junction 1 ACHE
neuronal cell body 2 APOB, APOE
smooth endoplasmic reticulum 2 APOB, HSP90B1
synaptic vesicle 1 BDNF
Cytoplasm, cytosol 1 NOS2
plasma membrane 9 ACHE, APOB, APOE, FADS2, FASN, FFAR4, GCG, NOS2, PIK3CA
Membrane 8 ACHE, APOE, BDNF, CPT1A, FADS1, FADS2, FASN, HSP90B1
axon 1 BDNF
caveola 1 PTGS2
extracellular exosome 4 APOB, APOE, FASN, HSP90B1
Lysosome membrane 1 FFAR4
endoplasmic reticulum 4 ADIPOQ, APOE, HSP90B1, PTGS2
extracellular space 10 ACHE, ADIPOQ, APOB, APOE, BDNF, CCL2, CXCL8, GCG, IL10, LEP
lysosomal lumen 1 APOB
perinuclear region of cytoplasm 5 ACHE, BDNF, HSP90B1, NOS2, PIK3CA
intercalated disc 1 PIK3CA
mitochondrion 2 CPT1A, FADS1
protein-containing complex 2 HSP90B1, PTGS2
intracellular membrane-bounded organelle 2 APOB, FADS1
Microsome membrane 1 PTGS2
Secreted 10 ACHE, ADIPOQ, APOB, APOE, BDNF, CCL2, CXCL8, GCG, IL10, LEP
extracellular region 11 ACHE, ADIPOQ, APOB, APOE, BDNF, CCL2, CXCL8, GCG, HSP90B1, IL10, LEP
Mitochondrion outer membrane 1 CPT1A
mitochondrial outer membrane 1 CPT1A
Extracellular side 1 ACHE
ciliary membrane 1 FFAR4
Endosome, multivesicular body 1 APOE
Extracellular vesicle 1 APOE
Secreted, extracellular space, extracellular matrix 1 APOE
chylomicron 2 APOB, APOE
high-density lipoprotein particle 1 APOE
low-density lipoprotein particle 2 APOB, APOE
multivesicular body 1 APOE
very-low-density lipoprotein particle 2 APOB, APOE
midbody 1 HSP90B1
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
Early endosome 2 APOB, APOE
Cytoplasm, perinuclear region 1 NOS2
focal adhesion 1 HSP90B1
extracellular matrix 1 APOE
Peroxisome 1 NOS2
basement membrane 1 ACHE
collagen trimer 1 ADIPOQ
peroxisomal matrix 1 NOS2
collagen-containing extracellular matrix 3 ADIPOQ, APOE, HSP90B1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
cilium 1 FFAR4
chromatin 1 PPARA
Secreted, extracellular space 1 APOE
blood microparticle 1 APOE
Lipid-anchor, GPI-anchor 1 ACHE
[Isoform 2]: Cell membrane 1 FFAR4
endosome lumen 1 APOB
Lipid droplet 1 APOB
[Isoform 1]: Endoplasmic reticulum membrane 1 FADS1
Melanosome 3 APOE, FASN, HSP90B1
side of membrane 1 ACHE
sperm plasma membrane 1 HSP90B1
secretory granule lumen 1 GCG
endoplasmic reticulum lumen 6 APOB, APOE, BDNF, GCG, HSP90B1, PTGS2
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
endocytic vesicle 1 FFAR4
endoplasmic reticulum exit site 1 APOB
clathrin-coated endocytic vesicle membrane 2 APOB, APOE
Sarcoplasmic reticulum lumen 1 HSP90B1
synaptic cleft 2 ACHE, APOE
[Isoform 1]: Cell membrane 1 FFAR4
[Isoform 2]: Endoplasmic reticulum membrane 1 FADS1
Cell projection, cilium membrane 1 FFAR4
discoidal high-density lipoprotein particle 1 APOE
endocytic vesicle lumen 3 APOB, APOE, HSP90B1
[Glucagon-like peptide 1]: Secreted 1 GCG
chylomicron remnant 2 APOB, APOE
intermediate-density lipoprotein particle 2 APOB, APOE
lipoprotein particle 1 APOE
multivesicular body, internal vesicle 1 APOE
cortical cytoskeleton 1 NOS2
mature chylomicron 1 APOB
endoplasmic reticulum chaperone complex 1 HSP90B1
[Isoform H]: Cell membrane 1 ACHE
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
glycogen granule 1 FASN


文献列表

  • Salim Makni, Sébastien Acket, Stéphanie Guenin, Sana Afensiss, Adeline Guellier, Raquel Martins-Noguerol, Antonio J Moreno-Perez, Brigitte Thomasset, Enrique Martinez-Force, Laurent Gutierrez, Eric Ruelland, Adrian Troncoso-Ponce. Arabidopsis seeds altered in the circadian clock protein TOC1 are characterized by higher level of linolenic acid. Plant science : an international journal of experimental plant biology. 2024 Jul; 344(?):112087. doi: 10.1016/j.plantsci.2024.112087. [PMID: 38599247]
  • Lin Liu, Ya Zhang, Meng-Di Yuan, Dong-Miao Xiao, Wei-Hua Xu, Qi Zheng, Qi-Wei Qin, You-Hua Huang, Xiao-Hong Huang. Integrated multi-omics analysis reveals liver metabolic reprogramming by fish iridovirus and antiviral function of alpha-linolenic acid. Zoological research. 2024 May; 45(3):520-534. doi: 10.24272/j.issn.2095-8137.2024.028. [PMID: 38682434]
  • Jingzhi Nie, Wenyue Ma, Xueyuan Ma, De Zhu, Xin Li, Caijin Wang, Guofeng Xu, Canni Chen, Dengjie Luo, Sichen Xie, Guanjing Hu, Peng Chen. Integrated Transcriptomic and Metabolomic Analysis Reveal the Dynamic Process of Bama Hemp Seed Development and the Accumulation Mechanism of α-Linolenic Acid and Linoleic Acid. Journal of agricultural and food chemistry. 2024 May; 72(19):10862-10878. doi: 10.1021/acs.jafc.3c09309. [PMID: 38712687]
  • Mostafa H Baky, Eman M El-Taher, Dina M Y El Naggar, Mostafa B Abouelela. Phytochemical investigation of the n-hexane-extracted oil from four umbelliferous vegetables using GC/MS analysis in the context of antibacterial activity. Scientific reports. 2024 05; 14(1):10592. doi: 10.1038/s41598-024-60631-4. [PMID: 38719900]
  • Nobuyuki Fukuoka, Ryusei Watanabe, Tatsuro Hamada. Impact of changes in root biomass on the occurrence of internal browning in radish root. Plant physiology and biochemistry : PPB. 2024 May; 210(?):108563. doi: 10.1016/j.plaphy.2024.108563. [PMID: 38554535]
  • Zhixiong Chen, Ni Hong, Cui Yan, Zhongbo Zheng, Jie Xi, Ping Cao. The potential of Paeonia lactiflora pall seeds oil as a pure natural cosmetics raw material: In Vitro findings. Journal of cosmetic dermatology. 2024 May; 23(5):1875-1883. doi: 10.1111/jocd.16204. [PMID: 38450923]
  • Marija Takić, Slavica Ranković, Zdenka Girek, Suzana Pavlović, Petar Jovanović, Vesna Jovanović, Ivana Šarac. Current Insights into the Effects of Dietary α-Linolenic Acid Focusing on Alterations of Polyunsaturated Fatty Acid Profiles in Metabolic Syndrome. International journal of molecular sciences. 2024 Apr; 25(9):. doi: 10.3390/ijms25094909. [PMID: 38732139]
  • Weizong Yang, Ziwei Xin, Qingyu Zhang, Yanlong Zhang, Lixin Niu. The tree peony DREB transcription factor PrDREB2D regulates seed α-linolenic acid accumulation. Plant physiology. 2024 Apr; 195(1):745-761. doi: 10.1093/plphys/kiae082. [PMID: 38365221]
  • Maciej Strzemski, Lubomir Adamec, Sławomir Dresler, Barbara Mazurek, Katarzyna Dubaj, Piotr Stolarczyk, Marcin Feldo, Bartosz J Płachno. Shoots and Turions of Aquatic Plants as a Source of Fatty Acids. Molecules (Basel, Switzerland). 2024 Apr; 29(9):. doi: 10.3390/molecules29092062. [PMID: 38731554]
  • Lena Hong, Peter Zahradka, Carla G Taylor. Differential Modulation by Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) of Mesenteric Fat and Macrophages and T Cells in Adipose Tissue of Obese fa/fa Zucker Rats. Nutrients. 2024 Apr; 16(9):. doi: 10.3390/nu16091311. [PMID: 38732558]
  • Jiaying Huo, Wu Peng, Hui Ouyang, Xiaolong Liu, Ping Wang, Xiongwei Yu, Tingting Xie, Shugang Li. Exploration of markers in oxidized rancidity walnut kernels based on lipidomics and volatolomics. Food research international (Ottawa, Ont.). 2024 Apr; 182(?):114141. doi: 10.1016/j.foodres.2024.114141. [PMID: 38519173]
  • Meijun Du, Mengyue Gong, Gangcheng Wu, Jun Jin, Xingguo Wang, Qingzhe Jin. Conjugated Linolenic Acid (CLnA) vs Conjugated Linoleic Acid (CLA): A Comprehensive Review of Potential Advantages in Molecular Characteristics, Health Benefits, and Production Techniques. Journal of agricultural and food chemistry. 2024 Mar; 72(11):5503-5525. doi: 10.1021/acs.jafc.3c08771. [PMID: 38442367]
  • Zeyan Chen, Yonghui Kong, Zishu Huang, Xiaoyu Zheng, Zhihong Zheng, Defu Yao, Shen Yang, Yueling Zhang, Jude Juventus Aweya. Exogenous alpha-linolenic acid and Vibrio parahaemolyticus induce EPA and DHA levels mediated by delta-6 desaturase to enhance shrimp immunity. International journal of biological macromolecules. 2024 Feb; 257(Pt 2):128583. doi: 10.1016/j.ijbiomac.2023.128583. [PMID: 38056755]
  • Maede Hasanpour, Ali Rezaie, Milad Iranshahy, Mojtaba Yousefi, Satar Saberi, Mehrdad Iranshahi. 1H NMR-based metabolomics study of the lipid profile of omega-3 fatty acid supplements and some vegetable oils. Journal of pharmaceutical and biomedical analysis. 2024 Jan; 238(?):115848. doi: 10.1016/j.jpba.2023.115848. [PMID: 37948777]
  • Smita Eknath Desale, Hariharakrishnan Chidambaram, Subashchandrabose Chinnathambi. Biochemical and Biophysical Characterization of Tau and α-Linolenic Acid Vesicles In Vitro. Methods in molecular biology (Clifton, N.J.). 2024; 2754(?):193-203. doi: 10.1007/978-1-0716-3629-9_11. [PMID: 38512668]
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