Ferulic acid (BioDeep_00000000309)

 

Secondary id: BioDeep_00000265017, BioDeep_00000400088, BioDeep_00000400145, BioDeep_00000400184

natural product human metabolite PANOMIX_OTCML-2023 blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid

化学式: C10H10O4 (194.057906)
中文名称: 阿魏酸
谱图信息: 最多检出来源 Homo sapiens(feces) 32.53%

Reviewed

Last reviewed on 2024-09-04.

Cite this Page

Ferulic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/ferulic_acid (retrieved 2024-12-04) (BioDeep RN: BioDeep_00000000309). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: c1(c(ccc(c1)/C=C/C(=O)O)O)OC
InChI: InChI=1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)

描述信息

trans-Ferulic acid is a highly abundant phenolic phytochemical which is present in plant cell walls. Ferulic acid is a phenolic acid that can be absorbed by the small intestine and excreted through the urine. It is one of the most abundant phenolic acids in plants, varying from 5 g/kg in wheat bran to 9 g/kg in sugar-beet pulp and 50 g/kg in corn kernel. It occurs primarily in seeds and leaves both in its free form (albeit rarely) and covalently linked to lignin and other biopolymers. It is usually found as ester cross-links with polysaccharides in the cell wall, such as arabinoxylans in grasses, pectin in spinach and sugar beet, and xyloglucans in bamboo. It also can cross-link with proteins. Due to its phenolic nucleus and an extended side chain conjugation (carbohydrates and proteins), it readily forms a resonance-stabilized phenoxy radical which accounts for its potent antioxidant potential. Food supplementation with curcumin and ferulic acid is considered a nutritional approach to reducing oxidative damage and amyloid pathology in Alzheimer disease (PMID:17127365, 1398220, 15453708, 9878519). Ferulic acid can be found in Pseudomonas and Saccharomyces (PMID:8395165).
Ferulic acid is a ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring. It has a role as an antioxidant, a MALDI matrix material, a plant metabolite, an anti-inflammatory agent, an apoptosis inhibitor and a cardioprotective agent. It is a conjugate acid of a ferulate.
Ferulic acid is a natural product found in Haplophyllum griffithianum, Visnea mocanera, and other organisms with data available.
Ferulic acid is a metabolite found in or produced by Saccharomyces cerevisiae.
See also: Angelica sinensis root (part of).
Widely distributed in plants, first isolated from Ferula foetida (asafoetida). Antioxidant used to inhibit oxidn. of fats, pastry products, etc. Antifungal agent used to prevent fruit spoilage. trans-Ferulic acid is found in many foods, some of which are deerberry, peach, shea tree, and common bean.
A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring.
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D005765 - Gastrointestinal Agents > D002756 - Cholagogues and Choleretics
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000975 - Antioxidants > D016166 - Free Radical Scavengers
D006401 - Hematologic Agents > D000925 - Anticoagulants
D020011 - Protective Agents > D000975 - Antioxidants
D000893 - Anti-Inflammatory Agents
D018501 - Antirheumatic Agents
Acquisition and generation of the data is financially supported in part by CREST/JST.
KEIO_ID H074
(E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1].
(E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1].
Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.
Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

同义名列表

95 个代谢物同义名

Ferulic Acid, Pharmaceutical Secondary Standard; Certified Reference Material; InChI=1/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13; trans-Ferulic acid, matrix substance for MALDI-MS, >=99.0\\% (HPLC); Ferulic acid, United States Pharmacopeia (USP) Reference Standard; trans-Ferulic acid, certified reference material, TraceCERT(R); Diethyl2-(acetamido)-2-(2-(bromomethyl)-5-nitrobenzyl)malonate; Ferulic acid, European Pharmacopoeia (EP) Reference Standard; 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (2E)-; 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (E)-; (E)-3-(3-methoxy-4-oxidanyl-phenyl)prop-2-enoic acid; (2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid; (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid; (E)-3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acid; (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid; (E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid; (2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-acrylic acid; (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoicacid; 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-; FERULIC ACID (CONSTITUENT OF BLACK COHOSH) [DSC]; Trans-3-(4-hydroxy-3-methoxyphenyl)acrylic acid; (2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoate; CINNAMIC ACID,4-HYDROXY,3-METHOXY FERULIC ACID; (2E)-3-(4-Hydroxy-3-methoxyphenyl)acrylic acid; 3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid; 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid; (E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoate; (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid; trans-Ferulic Acid (purified by sublimation); Cinnamic acid, 4-hydroxy-3-methoxy-, trans-; 3-(4-Hydroxy-3-methoxyphenyl)propenoic acid; FERULIC ACID (CONSTITUENT OF BLACK COHOSH); Cinnamic acid, 4-hydroxy-3-methoxy-, (E)-; 3-(4-Hydroxy-3-methoxyphenyl)acrylic acid; 3-methoxy-4-hydroxy-trans-cinnamic acid; 4-Hydroxy-3-methoxycinnamic acid, trans; 3-(4-Hydroxy-3-methoxyphenyl)propenoate; trans-3-methoxy-4-hydroxycinnamic acid; trans-4-Hydroxy-3-methoxycinnamic acid; (E)-4-hydroxy-3-methoxy-Cinnamic acid; trans-4-Hydroxy-3-methoxycinnamicacid; 4-HYDROXY-3-METHOXY-D3-CINNAMIC ACID; (E)-4-Hydroxy-3-methoxycinnamic acid; Cinnamic acid, 4-hydroxy-3-methoxy-; (E)4-hydroxy-3-methoxycinnamic acid; 3-Methoxy-4-hydroxy-trans-cinnamate; trans-4-Hydroxy-3-methoxycinnamate; 4’-Hydroxy-3’-methoxycinnamic acid; (E)-4-hydroxy-3-methoxy-Cinnamate; 4-Hydroxy-3-methoxy cinnamic acid; (e)-4-Hydroxy-3-methoxycinnamate; (E)-4-Hydroxy-3-methoxycinnamate; 4-Hydroxy-3-methoxycinnamic acid; 3-methoxy-4-hydroxycinnamic acid; 4-hydroxy-3-methoxycinnamic acid; ferulic acid, monosodium salt; 4-Hydroxy-3-methoxycinnamate; TRANS-FERULIC ACID [WHO-DD]; caffeic acid 3-methyl ether; Fumalic acid (Ferulic acid); trans-Ferulic acid, >=99\\%; trans-Ferulic acid, 99\\%; ferulic acid, (E)-isomer; ferulic acid, (Z)-isomer; FERULIC ACID [USP-RS]; FERULIC ACID (USP-RS); FERULIC ACID [WHO-DD]; Ferulic acid, trans-; FERULIC ACID [HSDB]; FERULIC ACID [INCI]; (E)-Coniferic acid; 8,8-diferulic acid; trans-ferulic acid; Ferulic acid (M5); trans-FerulicAcid; FERULIC ACID [MI]; Ferulic Acid ,(S); Spectrum5_000554; (E)-Ferulic acid; Ferulic acid, E-; cis-ferulic acid; CIS-FERULICACID; sodium ferulate; Coniferic acid; trans-Ferulate; Ferulaic acid; Ferulic acid; (E)-Ferulate; Fumalic acid; FERULIC-ACID; Ferulicacid; ferulasaure; ferulate; Ferulic; trans-Ferulic acid; Ferulate



数据库引用编号

48 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

226 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(1)

Plant Reactome(225)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2260 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Peng Shu, Jiaxin Mo, Zunjiang Li, Mingjie Li, Wei Zhu, Zhiyun Du. Ferulic acid in synergy with retinol alleviates oxidative injury of HaCaT cells during UVB-induced photoaging. Aging. 2024 Apr; 16(8):7153-7173. doi: 10.18632/aging.205749. [PMID: 38643459]
  • Sapna I, A Jayadeep. Enzyme-treated red rice (Oryza sativa L.) bran extracts mitigate inflammatory markers in RAW 264.7 macrophage cells and exhibit anti-inflammatory efficacy greater/comparable to ferulic acid, catechin, γ-tocopherol, and γ-oryzanol. Journal of ethnopharmacology. 2024 Apr; 323(?):117616. doi: 10.1016/j.jep.2023.117616. [PMID: 38142877]
  • Akihiro Shirai, Ami Tanaka. Effects of ferulic acid combined with light irradiation on deoxynivalenol and its production in Fusarium graminearum. Fungal biology. 2024 04; 128(2):1684-1690. doi: 10.1016/j.funbio.2024.02.003. [PMID: 38575241]
  • Xiaochong Zhu, Jieyuan Wu, Shizhong Li, La Xiang, Jian-Ming Jin, Chaoning Liang, Shuang-Yan Tang. Artificial Biosynthetic Pathway for Efficient Synthesis of Vanillin, a Feruloyl-CoA-Derived Natural Product from Eugenol. Journal of agricultural and food chemistry. 2024 Mar; 72(12):6463-6470. doi: 10.1021/acs.jafc.3c08723. [PMID: 38501643]
  • Jasmin Bayer, Petra Högger. Development and validation of a LC-MS/MS method for the quantification of phenolic compounds in human saliva after intake of a procyanidin-rich pine bark extract. Journal of pharmaceutical and biomedical analysis. 2024 Feb; 239(?):115914. doi: 10.1016/j.jpba.2023.115914. [PMID: 38101241]
  • Rania A Gawish, Esraa M Samy, Maha M Aziz. Ferulic acid protects against gamma-radiation induced liver injury via regulating JAK/STAT/Nrf2 pathways. Archives of biochemistry and biophysics. 2024 Jan; 753(?):109895. doi: 10.1016/j.abb.2024.109895. [PMID: 38244663]
  • Tomasz Kowalczyk, Joanna Sikora, Anna Merecz-Sadowska, Wirginia Kukula-Koch, Ewelina Synowiec, Agata Majda, Dawid Juda, Tomasz Śliwiński, Przemysław Sitarek. Biological Properties of Extracts Obtained from In Vitro Culture of Plectranthus scutellarioides in a Cell Model. International journal of molecular sciences. 2024 Jan; 25(2):. doi: 10.3390/ijms25021043. [PMID: 38256118]
  • Wenjing Ta, Jie Wang, Jihong Song, Xingyue Li, Jianxiang Wang, Wen Lu. Elucidation the mechanism of the active ingredient imperatorin promoting drug absorption in cell model. The Journal of pharmacy and pharmacology. 2024 Jan; ?(?):. doi: 10.1093/jpp/rgad127. [PMID: 38215001]
  • Zhihao Sun, Wenqiao An, Taiping He, Qingqing Liu, Ziming Wang, Pengmei Guo, Sanyin Zhang. Real-Time Detection of Ferulic Acid Effects on Rat Left Ventricle Using Pressure-Volume Conductivity Catheter. Journal of visualized experiments : JoVE. 2024 Jan; ?(203):. doi: 10.3791/65858. [PMID: 38284554]
  • Guanghui Li, Junle Li, Yee-Ying Lee, Chaoying Qiu, Xiaofang Zeng, Yong Wang. Pickering emulsions stabilized by chitosan-flaxseed gum-hyaluronic acid nanoparticles for controlled topical release of ferulic acid. International journal of biological macromolecules. 2024 Jan; 255(?):128086. doi: 10.1016/j.ijbiomac.2023.128086. [PMID: 37981278]
  • Huahua Li, Ziwei Peng, Yang Song, Minhang Dou, Xinying Lu, Minghui Li, Xiaofeng Zhai, Yan Gu, Rexidanmu Mamujiang, Shouying Du, Jie Bai. Study of the permeation-promoting effect and mechanism of solid microneedles on different properties of drugs. Drug delivery. 2023 Dec; 30(1):2165737. doi: 10.1080/10717544.2023.2165737. [PMID: 36644816]
  • Asif Hameed, Duc Hai Nguyen, Shih-Yao Lin, Paul Stothard, Poovarasan Neelakandan, Li-Sen Young, Chiu-Chung Young. Hormesis of glyphosate on ferulic acid metabolism and antifungal volatile production in rice root biocontrol endophyte Burkholderia cepacia LS-044. Chemosphere. 2023 Dec; 345(?):140511. doi: 10.1016/j.chemosphere.2023.140511. [PMID: 37871874]
  • Gulay Ozkan. Valorization of artichoke outer petals by using ultrasound-assisted extraction and natural deep eutectic solvents (NADES) for the recovery of phenolic compounds. Journal of the science of food and agriculture. 2023 Nov; ?(?):. doi: 10.1002/jsfa.13158. [PMID: 37989526]
  • Saarika Pothuvan Kunnummal, Nidhi Sori, Mudassir Azeez Khan, Mahejibin Khan. Plant-Based Nutraceutical Formulation Modulates the Human Gut Microbiota and Ferulic Acid Esterase Activity During In Vitro Fermentation. Current microbiology. 2023 Nov; 81(1):3. doi: 10.1007/s00284-023-03518-3. [PMID: 37940729]
  • Guanglu Wang, Jiajia Guo, Yeyun Ma, Yue Xin, Xiaomeng Ji, Ying Sun, Jian Zhang, Jingquan Dong. Ferulic acid alleviates carp brain damage and growth inhibition caused by avermectin by modulating the Nrf2/Keap1 and NF-κB signaling pathways. Pesticide biochemistry and physiology. 2023 Nov; 196(?):105590. doi: 10.1016/j.pestbp.2023.105590. [PMID: 37945241]
  • Yong Cheng, Xi Chen, Tian Yang, Zhaojun Wang, Qiuming Chen, Maomao Zeng, Fang Qin, Jie Chen, Zhiyong He. Effects of whey protein isolate and ferulic acid/phloridzin/naringin/cysteine on the thermal stability of mulberry anthocyanin extract at neutral pH. Food chemistry. 2023 Nov; 425(?):136494. doi: 10.1016/j.foodchem.2023.136494. [PMID: 37270886]
  • Fang Ma, Yuan Jiang, Baoshan Li, Yuxin Zeng, Hushan Shang, Fusheng Wang, Zhirong Sun. The Dynamic Accumulation Rules of Chemical Components during the Medicine Formation Period of Angelica sinensis and Chemometric Classifying Analysis for Different Bolting Times Using ATR-FTIR. Molecules (Basel, Switzerland). 2023 Oct; 28(21):. doi: 10.3390/molecules28217292. [PMID: 37959713]
  • Meryem Tourabi, Amira Metouekel, Asmae E L Ghouizi, Mohamed Jeddi, Ghizlane Nouioura, Hassan Laaroussi, Md Eram Hosen, Kawtar Fikri Benbrahim, Mohammed Bourhia, Ahmad Mohammad Salamatullah, Hiba-Allah Nafidi, Gezahign Fentahun Wondmie, Badiaa Lyoussi, Elhoussine Derwich. Efficacy of various extracting solvents on phytochemical composition, and biological properties of Mentha longifolia L. leaf extracts. Scientific reports. 2023 10; 13(1):18028. doi: 10.1038/s41598-023-45030-5. [PMID: 37865706]
  • Guojun Zhang, Linqin Meng, Rui Chen, Wen Wang, Xiangfeng Jing, Keyan Zhu-Salzman, Weining Cheng. Characterization of three glutathione S-transferases potentially associated with adaptation of the wheat blossom midge Sitodiplosis mosellana to host plant defense. Pest management science. 2023 Oct; ?(?):. doi: 10.1002/ps.7824. [PMID: 37814473]
  • Yu Wang, Jia-Jia Qi, Yi-Jing Yin, Hao Jiang, Jia-Bao Zhang, Shuang Liang, Bao Yuan. Ferulic Acid Enhances Oocyte Maturation and the Subsequent Development of Bovine Oocytes. International journal of molecular sciences. 2023 Sep; 24(19):. doi: 10.3390/ijms241914804. [PMID: 37834252]
  • Manas Kinra, Niraja Ranadive, Madhavan Nampoothiri, Devinder Arora, Jayesh Mudgal. Involvement of NLRP3 inflammasome pathway in the protective mechanisms of ferulic acid and p-coumaric acid in LPS-induced sickness behavior and neuroinflammation in mice. Naunyn-Schmiedeberg's archives of pharmacology. 2023 Sep; ?(?):. doi: 10.1007/s00210-023-02743-8. [PMID: 37755515]
  • Longkun Liu, Yoann Birling, Yan Zhao, Wenxin Ma, Yang Tang, Yuxin Sun, Xuehui Wang, Mingkun Yu, Hongsheng Bi, Jian-Ping Liu, Li Li, Zhaolan Liu. Mechanism of Chinese botanical drug Dizhi pill for myopia: An integrated study based on bioinformatics and network analysis. Medicine. 2023 Sep; 102(38):e34753. doi: 10.1097/md.0000000000034753. [PMID: 37747014]
  • Isra Ishtiaq, Ahmad Zeb, Haroon Badshah, Abdullah Alattar, Reem Alshaman, Phil Ok Koh, Najeeb Ur Rehman, Fawad Ali Shah, Yusuf S Althobaiti. Enhanced cardioprotective activity of ferulic acid-loaded solid lipid nanoparticle in an animal model of myocardial injury. Toxicology and applied pharmacology. 2023 Aug; 476(?):116657. doi: 10.1016/j.taap.2023.116657. [PMID: 37597755]
  • Shanbin Chen, Dong Zhao, Chunguang Luan, Jia Zheng, Wei Liu, Zheng Feng, Ruiqi Luo, Xinglin Han, Deliang Wang. Ferulic Acid Induces Autophagy and Apoptosis in Colon Cancer CT26 Cells via the MAPK Pathway. Molecules (Basel, Switzerland). 2023 Aug; 28(16):. doi: 10.3390/molecules28166014. [PMID: 37630266]
  • Seyedeh Zeynab Sharifsadat, Mahnaz Aghdasi, Faezeh Ghanati, Mohammad Hossein Arzanesh. Harmonized Biochemical Modification of Cell Walls to Get Permission for Entrance of Azospirillum sp. to Rice Roots. Plant science : an international journal of experimental plant biology. 2023 Aug; ?(?):111823. doi: 10.1016/j.plantsci.2023.111823. [PMID: 37572965]
  • Zhipeng Qiu, Ling Chen, Chenlu Rao, Bo Zheng. Starch-guar gum-ferulic acid molecular interactions alter the ordered structure and ultimate retrogradation properties and in vitro digestibility of chestnut starch under extrusion treatment. Food chemistry. 2023 Aug; 416(?):135803. doi: 10.1016/j.foodchem.2023.135803. [PMID: 36881961]
  • Yan Hui Yang, Hao Wei Song, Jun Yi Lai, Rui Fang Li, Zi Chao Wang, Hui Cong Jia, Yong Yang. A Rehmannia glutinosa caffeic acid O-methyltransferase functional identification: Reconstitution of the ferulic acid biosynthetic pathway in Saccharomyces cerevisiae using Rehmannia glutinosa enzymes. Biotechnology journal. 2023 Jul; ?(?):e2300064. doi: 10.1002/biot.202300064. [PMID: 37522376]
  • Sahar Y Al-Okbi, Ola Ali, A S Aly, D Refaat, Reham S H Esmail, Hagar F H Elbakry. Management of metabolic syndrome by nutraceuticals prepared from chitosan and ferulic acid with or without beta-sitosterol and their nanoforms. Scientific reports. 2023 07; 13(1):12176. doi: 10.1038/s41598-023-38837-9. [PMID: 37500657]
  • Sanchari Basu Mallik, Jayesh Mudgal, Manas Kinra, Susan Hall, Gary D Grant, Shailendra Anoopkumar-Dukie, Madhavan Nampoothiri, Yuqing Zhang, Devinder Arora. Involvement of indoleamine 2, 3-dioxygenase (IDO) and brain-derived neurotrophic factor (BDNF) in the neuroprotective mechanisms of ferulic acid against depressive-like behaviour. Metabolic brain disease. 2023 Jul; ?(?):. doi: 10.1007/s11011-023-01267-7. [PMID: 37490224]
  • Xue-Shan Dai, Qing-Hua Wei, Xin Guo, Yi Ding, Xiao-Qian Yang, Yu-Xin Zhang, Xiao-Yu Xu, Cong Li, Yi Chen. Ferulic acid, ligustrazine, and tetrahydropalmatine display the anti-proliferative effect in endometriosis through regulating Notch pathway. Life sciences. 2023 Jul; 328(?):121921. doi: 10.1016/j.lfs.2023.121921. [PMID: 37429417]
  • Sangeun Jeon, Jisub Hwang, Hackwon Do, Ly Thi Huong Luu Le, Chang Woo Lee, Wanki Yoo, Min Ju Lee, Seung Chul Shin, Kyeong Kyu Kim, Han-Woo Kim, Jun Hyuck Lee. Feruloyl Esterase (LaFae) from Lactobacillus acidophilus: Structural Insights and Functional Characterization for Application in Ferulic Acid Production. International journal of molecular sciences. 2023 Jul; 24(13):. doi: 10.3390/ijms241311170. [PMID: 37446348]
  • Giada Botti, Anna Bianchi, Alessandro Dalpiaz, Paola Tedeschi, Valentina Albanese, Milena Sorrenti, Laura Catenacci, Maria Cristina Bonferoni, Sarah Beggiato, Barbara Pavan. Dimeric ferulic acid conjugate as a prodrug for brain targeting after nasal administration of loaded solid lipid microparticles. Expert opinion on drug delivery. 2023 Jul; 20(11):1657-1679. doi: 10.1080/17425247.2023.2286369. [PMID: 38014509]
  • Zinuo Shen, Yang Wu, Lu Zhou, Qian Wang, Yang Tang, Yan Sun, Fengjie Zheng, Yuhang Li. The efficacy of sodium ferulate combination therapy in coronary heart disease: A systematic review and meta-analysis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Jul; 115(?):154829. doi: 10.1016/j.phymed.2023.154829. [PMID: 37116387]
  • Mahdi Daryagasht, Mehrnoosh Moosavi, Layasadat Khorsandi, Reza Azadnasab, Mohammad Javad Khodayar. Hepatoprotective and anti-hyperglycemic effects of ferulic acid in arsenic-exposed mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Jun; 178(?):113924. doi: 10.1016/j.fct.2023.113924. [PMID: 37393015]
  • Chunliu Wang, Jie Zhou, Shixiang Wang, Yang Liu, Kaihua Long, Tingting Sun, Wenbing Zhi, Yang Yang, Hong Zhang, Ye Zhao, Xiaopu Zheng, Xiaohui Zheng, Ye Li, Pu Jia. Guanxining injection alleviates fibrosis in heart failure mice and regulates SLC7A11/GPX4 axis. Journal of ethnopharmacology. 2023 Jun; 310(?):116367. doi: 10.1016/j.jep.2023.116367. [PMID: 36914037]
  • Jiaojiao Fu, Jingyan Yang, Liying He, Caixia Yang, Jing He, Yanan Hua, Jinlin Guo, Sijing Liu. Ferulic Acid Alleviates Hepatic Lipid Accumulation and Inflammation by Improving Proximal and Distal Intestinal Barriers in NAFLD Mice. The Tohoku journal of experimental medicine. 2023 Jun; 260(2):149-163. doi: 10.1620/tjem.2023.j023. [PMID: 36927682]
  • Jia Chen, Lingyan Zhang, Peng Zhao, Gaiqin Ma, Qi Li, Xiuzhu Yu. Synthesized alkyl ferulates with different chain lengths inhibited the formation of lipid oxidation products in soybean oil during deep frying. Food chemistry. 2023 Jun; 410(?):135458. doi: 10.1016/j.foodchem.2023.135458. [PMID: 36641917]
  • Han Wang, Lu Chen, Shuang Wu, Weiping Jin, Wangyang Shen, Zhongze Hu, Wenjing Huang, Gang Liu. Improve stability and application of rice oil bodies via surface modification with ferulic acid, (-)-epicatechin, and phytic acid. Food chemistry. 2023 May; 409(?):135274. doi: 10.1016/j.foodchem.2022.135274. [PMID: 36586252]
  • Li-Chao Zhang, Ya-Ning Liu, Xiao-Qin La, Shuai-Tao Li, Li-Na Wen, Ting Liu, Han-Qing Li, Ai-Ping Li, Haitao Wu, Chang-Xin Wu, Zhuo-Yu Li. The bound polyphenols of foxtail millet (Setaria italica) inner shell inhibit breast cancer by promoting lipid accumulation-induced autophagic death. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 May; ?(?):113855. doi: 10.1016/j.fct.2023.113855. [PMID: 37230459]
  • Xingxun Bao, Wei Li, Ruixue Jia, Dandan Meng, Hairong Zhang, Lei Xia. Molecular mechanism of ferulic acid and its derivatives in tumor progression. Pharmacological reports : PR. 2023 May; ?(?):. doi: 10.1007/s43440-023-00494-0. [PMID: 37202657]
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  • Qian Zhang, Meixuan Li, Guiyan Yang, Xiaoqiang Liu, Zhongdong Yu, Shaobing Peng. Protocatechuic acid, ferulic acid and relevant defense enzymes correlate closely with walnut resistance to Xanthomonas arboricola pv. juglandis. BMC plant biology. 2022 Dec; 22(1):598. doi: 10.1186/s12870-022-03997-9. [PMID: 36539704]
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  • Xin-Yu Lin, Jing Zhou, Cai-Feng Hao, He Zhu, Shan-Shan Zhou, Jin-Di Xu, Qian Mao, Song-Lin Li, Ming Kong. Quality consistency evaluation of commercial Prunellae Spica by integrating determination of secondary metabolites and saccharides. Phytochemical analysis : PCA. 2022 Dec; ?(?):. doi: 10.1002/pca.3197. [PMID: 36494085]
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  • Zhenxing Li, Binxin Yang, Hongwu Liu, Yue Ding, Zimian Fang, Wubin Shao, Puying Qi, Xiang Zhou, Liwei Liu, Song Yang. The Discovery of Novel Ferulic Acid Derivatives Incorporating Substituted Isopropanolamine Moieties as Potential Tobacco Mosaic Virus Helicase Inhibitors. International journal of molecular sciences. 2022 Nov; 23(22):. doi: 10.3390/ijms232213991. [PMID: 36430473]
  • Janne Tampio, Magdalena Markowicz-Piasecka, Ahmed Montaser, Jaana Rysä, Anu Kauppinen, Kristiina M Huttunen. L-type Amino Acid Transporter 1 Utilizing Ferulic Acid Derivatives Show Increased Drug Delivery in the Mouse Pancreas Along with Decreased Lipid Peroxidation and Prostaglandin Production. Molecular pharmaceutics. 2022 11; 19(11):3806-3819. doi: 10.1021/acs.molpharmaceut.2c00328. [PMID: 36027044]
  • Hardeep Singh Tuli, Ajay Kumar, Seema Ramniwas, Renuka Coudhary, Diwakar Aggarwal, Manoj Kumar, Ujjawal Sharma, Nidarshana Chaturvedi Parashar, Shafiul Haque, Katrin Sak. Ferulic Acid: A Natural Phenol That Inhibits Neoplastic Events through Modulation of Oncogenic Signaling. Molecules (Basel, Switzerland). 2022 Nov; 27(21):. doi: 10.3390/molecules27217653. [PMID: 36364478]
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