NCBI Taxonomy: 35939
Impatiens (ncbi_taxid: 35939)
found 26 associated metabolites at genus taxonomy rank level.
Ancestor: Balsaminaceae
Child Taxonomies: Impatiens pallida, Impatiens boni, Impatiens noei, Impatiens nana, Impatiens lawii, Impatiens rosea, Impatiens putii, Impatiens aurea, Impatiens mannii, Impatiens catati, Impatiens hamata, Impatiens ioides, Impatiens lucida, Impatiens patula, Impatiens compta, Impatiens repens, Impatiens oumina, Impatiens viscida, Impatiens lotteri, Impatiens apsotis, Impatiens pendula, Impatiens devolii, Impatiens aurella, Impatiens grandis, Impatiens koreana, Impatiens debilis, Impatiens cecilii, Impatiens confusa, Impatiens hawkeri, Impatiens tenella, Impatiens serrata, Impatiens bicolor, Impatiens serpens, Impatiens elianae, Impatiens frithii, Impatiens opinata, Impatiens peltata, Impatiens acaulis, Impatiens elegans, Impatiens ruthiae, Impatiens salpinx, Impatiens engleri, Impatiens tigrina, Impatiens goughii, Impatiens viscosa, Impatiens poilanei, Impatiens issembei, Impatiens ecornuta, Impatiens nzabiana, Impatiens mexicana, Impatiens alpicola, Impatiens briartii, Impatiens gordonii, Impatiens digitata, Impatiens eryaleia, Impatiens irvingii, Impatiens discolor, Impatiens beccarii, Impatiens javensis, Impatiens radicans, Impatiens puberula, Impatiens TH-2023a, Impatiens TH-2023b, Impatiens uniflora, Impatiens tribuana, Impatiens tweediae, Impatiens charanii, Impatiens charisma, Impatiens sterilis, Impatiens larsenii, Impatiens parishii, Impatiens cristata, Impatiens flaccida, Impatiens kivuensis, Impatiens ludewigii, Impatiens thomensis, Impatiens wilksiana, Impatiens devendrae, Impatiens bomiensis, Impatiens bicaudata, Impatiens assurgens, Impatiens calcicola, Impatiens akomensis, Impatiens ethiopica, Impatiens balfourii, Impatiens notolopha, Impatiens alboflava, Impatiens occultans, Impatiens fruticosa, Impatiens pradhanii, Impatiens bisaccata, Impatiens wallichii, Impatiens volkensii, Impatiens laurentii, Impatiens mandrakae, Impatiens potaninii, Impatiens damrongii, Impatiens stenantha, Impatiens garrettii, Impatiens longiloba, Impatiens phoenicea, Impatiens mirabilis, Impatiens muscicola, Impatiens sylvicola, Impatiens smetsiana, Impatiens wuyiensis, Impatiens filicornu, Impatiens siamensis, Impatiens zombensis, Impatiens tribounii, Impatiens vaughanii, Impatiens sakeriana, Impatiens shirensis, Impatiens mackeyana, Impatiens lutzmannii, Impatiens versicolor, Impatiens etindensis, Impatiens buccinalis, Impatiens manteroana, Impatiens majumdarii, Impatiens rapiformis, Impatiens chevalieri, Impatiens macroptera, Impatiens chonoceras, Impatiens junghuhnii, Impatiens palpebrata, Impatiens percordata, Impatiens thamnoidea, Impatiens adenioides, Impatiens daraneenae, Impatiens auriculata, Impatiens foxworthyi, Impatiens floribunda, Impatiens yilingiana, Impatiens phengklaii, Impatiens psittacina, Impatiens reticulata, Impatiens santisukii, Impatiens wuerstenii, Impatiens hypophylla, Impatiens violiflora, Impatiens bahanensis, Impatiens ruiliensis, Impatiens putaoensis, Impatiens bokorensis, Impatiens nimspurjae, Impatiens eriosperma, Impatiens clavicornu, Impatiens brevicornis, Impatiens urundiensis, Impatiens x troupinii, Impatiens damingensis, Impatiens nushanensis, Impatiens fenghwaiana, Impatiens glandiflora, Impatiens fasciculata, Impatiens coelotropis, Impatiens microcentra, Impatiens turrialbana, Impatiens arachnoides, Impatiens bururiensis, Impatiens loulanensis, Impatiens manillensis, Impatiens mildbraedii, Impatiens ekapaksiana, Impatiens kunyitensis, Impatiens pyrhotricha, Impatiens rubricaulis, Impatiens cinnabarina, Impatiens gesneroidea, Impatiens ulugurensis, Impatiens masoalensis, Impatiens nyungwensis, Impatiens circaeoides, Impatiens rutenbergii, Impatiens trichoceras, Impatiens warburgiana, Impatiens macrosepala, Impatiens nalampoonii, Impatiens namkatensis, Impatiens spectabilis, Impatiens casseabriae, Impatiens eberhardtii, Impatiens edgeworthii, Impatiens hukaungensis, Impatiens diversifolia, Impatiens kleiniformis, Impatiens chimiliensis, Impatiens glandulifera, Impatiens guizhouensis, Impatiens kerinciensis, Impatiens pseudohamata, Impatiens raphidothrix, Impatiens paucidentata, Impatiens pinganoensis, Impatiens chloroxantha, Impatiens shimianensis, Impatiens palliderosea, Impatiens salaengensis, Impatiens hochstetteri, Impatiens kamerunensis, Impatiens dolichoceras, Impatiens linghziensis, Impatiens longlinensis, unclassified Impatiens, Impatiens yunlingensis, Impatiens plicatisepala, Impatiens longiaristata, Impatiens kinabaluensis, Impatiens linearisepala, Impatiens amplexicaulis, Impatiens cardamomensis, Impatiens diepenhorstii, Impatiens elephanticeps, Impatiens pseudoacaulis, Impatiens subecalcarata, Impatiens pilosivittata, Impatiens tapanuliensis, Impatiens angustisepala, Impatiens chumphonensis, Impatiens longyangensis, Impatiens mazumbaiensis, Impatiens phuluangensis, Impatiens rubromaculata, Impatiens huangyanensis, Impatiens sirindhorniae, Impatiens langbianensis, Impatiens chungtienensis, Impatiens blepharosepala, Impatiens fanjingshanica, Impatiens yingjiangensis, Impatiens incertae sedis, Impatiens chiangdaoensis, Impatiens kamtilongensis, Impatiens lukwangulensis, Impatiens msisimwanensis, Impatiens phahompokensis, Impatiens hydrogetonoides, Impatiens pseudozombensis, Impatiens sidikalangensis, Impatiens elatostemmoides, Impatiens yaojiapingensis, Impatiens pseudochinensis, Impatiens namchabarwensis, Impatiens purpureoviolacea, Impatiens qingchengshanica, Impatiens batanggadisensis, Impatiens pseudomacroptera, Impatiens psychadelphoides, Impatiens tanintharyiensis, Impatiens subgen. Impatiens, Impatiens quintadecimacopii, Impatiens subgen. Clavicarpa, Impatiens aff. catati SJ-2020, Impatiens cf. pallida GPM-2008, Impatiens balfourii x Impatiens parviflora, Impatiens aff. kanburiensis Suksathan 4573, Impatiens aff. violiflora Ruchisansakun 170, Impatiens kilimanjari x Impatiens pseudoviola, Impatiens cf. notoptera Suksathan & Triboun 4578, Impatiens cf. rubricolor Suksathan & Wongnak 5473, Impatiens purpureoviolacea x Impatiens gesneroidea, Impatiens cf. attopeuensis Suksathan & Wongnak 5474, Impatiens cf. scortechinii Suksathan & Triboun 4846
Luteolin
Luteolin is a naturally occurring flavonoid. (PMID:17168665). The flavonoids are polyphenolic compounds found as integral components of the human diet. They are universally present as constituents of flowering plants, particularly of food plants. The flavonoids are phenyl substituted chromones (benzopyran derivatives) consisting of a 15-carbon basic skeleton (C6-C3-C6), composed of a chroman (C6-C3) nucleus (the benzo ring A and the heterocyclic ring C), also shared by the tocopherols, with a phenyl (the aromatic ring B) substitution usually at the 2-position. Different substitutions can typically occur in the rings, A and B. Several plants and spices containing flavonoid derivatives have found application as disease preventive and therapeutic agents in traditional medicine in Asia for thousands of years. The selection of a particular food plant, plant tissue or herb for its potential health benefits appears to mirror its flavonoid composition. The much lower risk of colon, prostate and breast cancers in Asians, who consume more vegetables, fruits and tea than populations in the Western hemisphere do, raises the question of whether flavonoid components mediate the protective effects of diets rich in these foodstuffs by acting as natural chemopreventive and anticancer agents. An impressive body of information exists on the antitumoral action of plant flavonoids. In vitro work has concentrated on the direct and indirect actions of flavonoids on tumor cells, and has found a variety of anticancer effects such as cell growth and kinase activity inhibition, apoptosis induction, suppression of the secretion of matrix metalloproteinases and of tumor invasive behavior. Furthermore, some studies have reported the impairment of in vivo angiogenesis by dietary flavonoids. Experimental animal studies indicate that certain dietary flavonoids possess antitumoral activity. The hydroxylation pattern of the B ring of the flavones and flavonols, such as luteolin seems to critically influence their activities, especially the inhibition of protein kinase activity and antiproliferation. The different mechanisms underlying the potential anticancer action of plant flavonoids await further elucidation. Certain dietary flavonols and flavones targeting cell surface signal transduction enzymes, such as protein tyrosine and focal adhesion kinases, and the processes of angiogenesis appear to be promising candidates as anticancer agents. Further in vivo studies of these bioactive constituents is deemed necessary in order to develop flavonoid-based anticancer strategies. In view of the increasing interest in the association between dietary flavonoids and cancer initiation and progression, this important field is likely to witness expanded effort and to attract and stimulate further vigorous investigations (PMID:16097445). Luteolin is a tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 4, 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers. It has a role as an EC 2.3.1.85 (fatty acid synthase) inhibitor, an antineoplastic agent, a vascular endothelial growth factor receptor antagonist, a plant metabolite, a nephroprotective agent, an angiogenesis inhibitor, a c-Jun N-terminal kinase inhibitor, an anti-inflammatory agent, an apoptosis inducer, a radical scavenger and an immunomodulator. It is a 3-hydroxyflavonoid and a tetrahydroxyflavone. It is a conjugate acid of a luteolin-7-olate. Luteolin is a natural product found in Verbascum lychnitis, Carex fraseriana, and other organisms with data available. Luteolin is a naturally-occurring flavonoid, with potential anti-oxidant, anti-inflammatory, apoptosis-inducing and chemopreventive activities. Upon administration, luteolin scavenges free radicals, protects cells from reactive oxygen species (ROS)-induced damage and induces direct cell cycle arrest and apoptosis in tumor cells. This inhibits tumor cell proliferation and suppresses metastasis. 5,7,3,4-tetrahydroxy-flavone, one of the FLAVONES. See also: Chamomile (part of); Cannabis sativa subsp. indica top (part of); Fenugreek seed (part of). A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 4, 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers. Flavone v. widespread in plant world; found especies in celery, peppermint, rosemary, thyme and Queen Annes Lace leaves (wild carrot). Potential nutriceutical. Luteolin is found in many foods, some of which are soy bean, ginger, abalone, and swiss chard. Acquisition and generation of the data is financially supported in part by CREST/JST. IPB_RECORD: 361; CONFIDENCE confident structure CONFIDENCE standard compound; INTERNAL_ID 48 Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells[1][2][3]. Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells[1][2][3].
Ferulic acid
trans-Ferulic acid is a highly abundant phenolic phytochemical which is present in plant cell walls. Ferulic acid is a phenolic acid that can be absorbed by the small intestine and excreted through the urine. It is one of the most abundant phenolic acids in plants, varying from 5 g/kg in wheat bran to 9 g/kg in sugar-beet pulp and 50 g/kg in corn kernel. It occurs primarily in seeds and leaves both in its free form (albeit rarely) and covalently linked to lignin and other biopolymers. It is usually found as ester cross-links with polysaccharides in the cell wall, such as arabinoxylans in grasses, pectin in spinach and sugar beet, and xyloglucans in bamboo. It also can cross-link with proteins. Due to its phenolic nucleus and an extended side chain conjugation (carbohydrates and proteins), it readily forms a resonance-stabilized phenoxy radical which accounts for its potent antioxidant potential. Food supplementation with curcumin and ferulic acid is considered a nutritional approach to reducing oxidative damage and amyloid pathology in Alzheimer disease (PMID:17127365, 1398220, 15453708, 9878519). Ferulic acid can be found in Pseudomonas and Saccharomyces (PMID:8395165). Ferulic acid is a ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring. It has a role as an antioxidant, a MALDI matrix material, a plant metabolite, an anti-inflammatory agent, an apoptosis inhibitor and a cardioprotective agent. It is a conjugate acid of a ferulate. Ferulic acid is a natural product found in Haplophyllum griffithianum, Visnea mocanera, and other organisms with data available. Ferulic acid is a metabolite found in or produced by Saccharomyces cerevisiae. See also: Angelica sinensis root (part of). Widely distributed in plants, first isolated from Ferula foetida (asafoetida). Antioxidant used to inhibit oxidn. of fats, pastry products, etc. Antifungal agent used to prevent fruit spoilage. trans-Ferulic acid is found in many foods, some of which are deerberry, peach, shea tree, and common bean. A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring. D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D005765 - Gastrointestinal Agents > D002756 - Cholagogues and Choleretics D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents D002491 - Central Nervous System Agents > D000700 - Analgesics D000975 - Antioxidants > D016166 - Free Radical Scavengers D006401 - Hematologic Agents > D000925 - Anticoagulants D020011 - Protective Agents > D000975 - Antioxidants D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents Acquisition and generation of the data is financially supported in part by CREST/JST. KEIO_ID H074 (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1]. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1]. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.
Soyasaponin A1
Soyasaponin A1 is found in pulses. Soyasaponin A1 is isolated from soybean (Glycine max).
Luteolin
Annotation level-1 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.976 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.975 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.968 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.971 Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells[1][2][3]. Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells[1][2][3].
Ferulic acid
(E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1]. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1]. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.
Octadecatetraenoic acid
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents D004396 - Coloring Agents > D005456 - Fluorescent Dyes