Vanillin (BioDeep_00000000091)

 

Secondary id: BioDeep_00000269025, BioDeep_00000859823

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite Volatile Flavor Compounds


代谢物信息卡片


Vanillin melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material

化学式: C8H8O3 (152.0473418)
中文名称: 4-羟基-3-甲氧基-13C-苯甲醛, 香草醛, 香兰素
谱图信息: 最多检出来源 Viridiplantae(plant) 0.02%

分子结构信息

SMILES: COC1=C(C=CC(=C1)C=O)O
InChI: InChI=1/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H3

描述信息

Vanillin, also known as vanillaldehyde or lioxin, belongs to the class of organic compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. It is used by the food industry as well as ethylvanillin. Vanillin exists in all living species, ranging from bacteria to humans. Vanillin is a sweet, chocolate, and creamy tasting compound. Vanillin is found, on average, in the highest concentration within a few different foods, such as corns, ryes, and sherries and in a lower concentration in beers, rums, and oats. Vanillin has also been detected, but not quantified, in several different foods, such as gooseberries, other bread, brazil nuts, shea tree, and ohelo berries. This could make vanillin a potential biomarker for the consumption of these foods. Vanillin is a potentially toxic compound. Synthetic vanillin, instead of natural Vanillin extract, is sometimes used as a flavouring agent in foods, beverages, and pharmaceuticals. Vanillin is the primary component of the extract of the Vanillin bean. Because of the scarcity and expense of natural Vanillin extract, there has long been interest in the synthetic preparation of its predominant component. Artificial Vanillin flavoring is a solution of pure vanillin, usually of synthetic origin. Today, artificial vanillin is made from either guaiacol or from lignin, a constituent of wood which is a byproduct of the paper industry. The first commercial synthesis of vanillin began with the more readily available natural compound eugenol.
Vanillin appears as white or very slightly yellow needles.
Vanillin is a member of the class of benzaldehydes carrying methoxy and hydroxy substituents at positions 3 and 4 respectively. It has a role as a plant metabolite, an anti-inflammatory agent, a flavouring agent, an antioxidant and an anticonvulsant. It is a member of phenols, a monomethoxybenzene and a member of benzaldehydes.
Vanillin is a natural product found in Ficus erecta var. beecheyana, Pandanus utilis, and other organisms with data available.
Vanillin is the primary component of the extract of the vanilla bean. Synthetic vanillin, instead of natural vanilla extract, is sometimes used as a flavouring agent in foods, beverages, and pharmaceuticals. It is used by the food industry as well as ethylvanillin.Artificial vanilla flavoring is a solution of pure vanillin, usually of synthetic origin. Because of the scarcity and expense of natural vanilla extract, there has long been interest in the synthetic preparation of its predominant component. The first commercial synthesis of vanillin began with the more readily available natural compound eugenol. Today, artificial vanillin is made from either guaiacol or from lignin, a constituent of wood which is a byproduct of the paper industry. (Wiki).
Vanillin is a metabolite found in or produced by Saccharomyces cerevisiae.
Constituent of vanilla (Vanilla subspecies) and many other plants, e.g. Peru balsam, clove bud oil. Widely used flavouring agent especies in cocoa products. obtained from spent wood-pulp liquors. Vanillin is found in many foods, some of which are pomes, elderberry, common cabbage, and dock.
A member of the class of benzaldehydes carrying methoxy and hydroxy substituents at positions 3 and 4 respectively.
D002491 - Central Nervous System Agents > D000927 - Anticonvulsants
D020011 - Protective Agents > D016587 - Antimutagenic Agents
D020011 - Protective Agents > D000975 - Antioxidants
CONFIDENCE standard compound; ML_ID 59
Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine.
Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine.

同义名列表

107 个代谢物同义名

Vanillin melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material; Vanillin Melting Point Standard, United States Pharmacopeia (USP) Reference Standard; Vanillin, Pharmaceutical Secondary Standard; Certified Reference Material; Vanillin, United States Pharmacopeia (USP) Reference Standard; Vanillin, European Pharmacopoeia (EP) Reference Standard; InChI=1/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H; Vanillin, TraceCERT(R), certified reference material; 1-(AMINOMETHYL)-CYCLOPROPANECARBOXYLICACIDETHYLESTER; 4-hydroxy-3-methoxy-Benzaldehyde-5-chlorovanillin; 4-hydroxy-3-methoxybenzaldehyde (ACD/Name 4.0); Vanillin (83 degrees C) Melting Point Standard; vanillin (3-methoxy-4-hydroxy- benzaldehyde); 4-08-00-01763 (Beilstein Handbook Reference); 4-Hydroxy-3-methoxybenzaldehyde(Vanilline); 3-Methoxy-4-hydroxybenzaldehyde (vanillin); 4-hydroxy-3-methoxybenzaldehyde (vanillin); Vanillin, Vetec(TM) reagent grade, 98\\%; Vanillin, tested according to Ph.Eur.; Vanillin, JIS special grade, >=98.0\\%; Protocatechualdehyde 3-methyl ether; trans-2-Ethoxy-5-(1-propenyl)phenol; 4-hydoxy-3-(methyloxy)benz aldehyde; Benzaldehyde, 4-hydroxy-3-methoxy-; Vanillin, natural, >=97\\%, FCC, FG; 4-hydoxy-3-(methyloxy)benzaldehyde; 4-hydroxy-3-(methoxy)benzaldehyde; 3-methoxy-4-hydroxy benzoaldehyde; 4-hydroxy-3-methoxy benzaldehyde; 3-methoxy-4-hydroxy-benzaldehyde; 4-Hydroxy-3-methoxy-benzaldehyde; 3-methoxy-4-hydroxy benzaldehyde; 4-HYDROXY,3-METHOXY-BENZALDEHYDE; 4-hydroxy-3-methoxy-benzyldehyde; p-Hydroxy-m-methoxybenzaldehyde; 4-hydroxy-3-methoxybenzaldehyde; 4-Hydroxy-5-methoxybenzaldehyde; Vanillin Melting Point Standard; Vanilla oleoresin (vanilla SPP); 4-hydroxy 3-methoxybenzaldehyde; 3-Methoxy-4-hydroxybenzaldehyde; m-Methoxy-p-hydroxybenzaldehyde; Vanillin, ReagentPlus(R), 99\\%; Methylprotocatechuic aldehyde; Protocatechualdehyde, methyl-; Methylprotcatechuic aldehyde; methyl-Protocatechualdehyde; m-Anisaldehyde, 4-hydroxy-; METHYLPROTOCATECHUALDEHYDE; Vanillin, puriss., 99.5\\%; Vanillin, >=97\\%, FCC, FG; oleo-Resins vanilla-bean; 2-Methoxy-4-formylphenol; VANILLIN, NATURAL [FHFI]; 4-Formyl-2-methoxyphenol; 4-Hydroxy-m-anisaldehyde; VANILLIN (EP MONOGRAPH); VANILLIN [EP MONOGRAPH]; VANILLIN (METHOXY-13C); vanillin, sodium salt; Vanillin sodium salt; Vanillin (Standard); oleo-Resins vanilla; Vanillin (natural); VANILLIN [USP-RS]; VANILLIN [WHO-DD]; Vanilla oleoresin; Vanillic aldehyde; Oleoresin vanilla; Vanillin, natural; VANILLIN [VANDF]; 5-chlorovanillin; Propenylguaethol; VANILLIN (MART.); VANILLIN [MART.]; 5-bromovanillin; VANILLIN [INCI]; WLN: VHR DQ CO1; VANILLIN [FHFI]; VANILLIN [HSDB]; Vanillin [USAN]; VANILLIN [FCC]; vanillaldehyde; Tox21_113534_1; VANILLIN [II]; Vanillin [NF]; Vanillin (NF); VANILLIN (II); VANILLIN [MI]; Tox21_113534; Tox21_300352; NCI60_001085; Tox21_201925; p-Vanillin; Vanilline; AI3-00093; Vanillin; Rhovanil; vaniline; Vanillum; Vanilin; Vanilla; Lioxin; Zimco; V55; Vanillin; 4-Hydroxy-3-methoxy-benzaldehyde; Vanillin



数据库引用编号

30 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(3)

PlantCyc(1)

代谢反应

15 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(12)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(3)

  • vanillin biosynthesis I: 4-hydroxybenzaldehyde + O2 + a reduced [NADPH-hemoprotein reductase] ⟶ 3,4-dihydroxybenzaldehyde + H2O + an oxidized [NADPH-hemoprotein reductase]
  • capsaicin biosynthesis: H+ + NADPH + a malonyl-[acp] + isobutanoyl-CoA ⟶ 8-methyl-6-nonenoate + H2O + NADP+ + a holo-[acyl-carrier protein] + coenzyme A
  • capsaicin biosynthesis: 8-methyl-6-nonenoate + vanillylamine ⟶ H2O + capsaicin

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

775 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Abeer S Elsherbiny, Alyaa Galal, Khalid M Ghoneem, Nehal A Salahuddin. Graphene oxide-based nanocomposites for outstanding eco-friendly antifungal potential against tomato phytopathogens. Biomaterials advances. 2024 Jun; 160(?):213863. doi: 10.1016/j.bioadv.2024.213863. [PMID: 38642516]
  • Bijoy Biswas, Manish Sakhakarmy, Tawsif Rahman, Hossein Jahromi, Sushil Adhikari, Bhavya B Krishna, Thallada Bhaskar, Jonas Baltrusaitis, Mohamed Eisa, Seyed Morteza Taghavi Kouzehkanan, Tae-Sik Oh. Selective production of phenolic monomer via catalytic depolymerization of lignin over cobalt-nickel-zirconium dioxide catalyst. Bioresource technology. 2024 Apr; 398(?):130517. doi: 10.1016/j.biortech.2024.130517. [PMID: 38437961]
  • Natalia Saudade de Aguiar, Fabricio Augusto Hansel, Cristiane Aparecida Fioravante Reis, Marcelo Lazzarotto, Ivar Wendling. Optimizing the Vanillin-Acid Sulfuric Method to Total Saponin Content in Leaves of Yerba Mate Clones. Chemistry & biodiversity. 2024 Apr; 21(4):e202301883. doi: 10.1002/cbdv.202301883. [PMID: 38358959]
  • Xiaochong Zhu, Jieyuan Wu, Shizhong Li, La Xiang, Jian-Ming Jin, Chaoning Liang, Shuang-Yan Tang. Artificial Biosynthetic Pathway for Efficient Synthesis of Vanillin, a Feruloyl-CoA-Derived Natural Product from Eugenol. Journal of agricultural and food chemistry. 2024 Mar; 72(12):6463-6470. doi: 10.1021/acs.jafc.3c08723. [PMID: 38501643]
  • Mervt M Almostafa, Maged E Mohamed, Nancy S Younis. Ameliorative effects of vanillin against pentylenetetrazole-induced epilepsy and associated memory loss in mice: The role of Nrf2/HO-1/NQO1 and HMGB1/RAGE/TLR4/NFκB pathways. International immunopharmacology. 2024 Mar; 129(?):111657. doi: 10.1016/j.intimp.2024.111657. [PMID: 38335655]
  • Yang Yang, Justin Flaven-Pouchon, Jerôme Cortot, Jean-François Ferveur, Bernard Moussian. Colorimetric surface lipid quantification in Drosophila. Archives of insect biochemistry and physiology. 2024 Feb; 115(2):e22091. doi: 10.1002/arch.22091. [PMID: 38385805]
  • Yanfei Huang, Yuhua Yang, Jinghua Xue, Yinyin Liao, Xiumin Fu, Chen Zhu, Jianlong Li, Lanting Zeng, Ziyin Yang. Biosynthetic Pathway and Bioactivity of Vanillin, a Highly Abundant Metabolite Distributed in the Root Cortex of Tea Plants (Camellia sinensis). Journal of agricultural and food chemistry. 2024 Jan; 72(3):1660-1673. doi: 10.1021/acs.jafc.3c07206. [PMID: 38193455]
  • Ryota Nakaniwa, Yuki Misawa, Saika Nakasato, Kaori Sano, Yoshiyuki Tanaka, Sachie Nakatani, Kenji Kobata. Biochemical Aspects of Putative Aminotransferase Responsible for Converting Vanillin to Vanillylamine in the Capsaicinoid Biosynthesis Pathway in Capsicum Plants. Journal of agricultural and food chemistry. 2024 Jan; 72(1):559-565. doi: 10.1021/acs.jafc.3c07369. [PMID: 38134368]
  • Yuan Gao, Jiang Liu, Xiaoyan Wang, Qiang Meng. Vanillin attenuates oxidative stress and neurochemical balance in MPTP-induced Parkinson's disease mice by regulating the TLR-4 inflammatory pathway. Folia neuropathologica. 2024 Jan; ?(?):. doi: 10.5114/fn.2023.131191. [PMID: 38174675]
  • Luis Chel-Guerrero, David Betancur-Ancona, Manuel Aguilar-Vega, Wilbert Rodríguez-Canto. Films properties of QPM corn starch with Delonix regia seed galactomannan as an edible coating material. International journal of biological macromolecules. 2024 Jan; 255(?):128408. doi: 10.1016/j.ijbiomac.2023.128408. [PMID: 38016603]
  • Marco A Ramírez-Mosqueda, Marco Vinicio Rodríguez-Deméneghi, Heidi P Medorio-García, Rubén H Andueza-Noh. Large-Scale Micropropagation of Vanilla (Vanilla planifolia Jacks.) in a Temporary Immersion Bioreactor (TIB). Methods in molecular biology (Clifton, N.J.). 2024; 2759(?):45-52. doi: 10.1007/978-1-0716-3654-1_4. [PMID: 38285137]
  • Muhammad Abu Taher, Xiaolin Wang, K M Faridul Hasan, Mohammad Raza Miah, Jin Zhu, Jing Chen. Lignin Modification for Enhanced Performance of Polymer Composites. ACS applied bio materials. 2023 Dec; 6(12):5169-5192. doi: 10.1021/acsabm.3c00783. [PMID: 38036466]
  • Mohamed A El Hamd, Mahmoud El-Maghrabey, Saud Almawash, Rania El-Shaheny, Galal Magdy. Self-ratiometric fluorescence approach based on plant extract-assisted synthesized silver nanoparticles for the determination of vanillin. Mikrochimica acta. 2023 12; 191(1):16. doi: 10.1007/s00604-023-06093-3. [PMID: 38086991]
  • Mahdi Aalikhani, Ensie Taheri, Masoumeh Khalili. Vanillin serves as a potential substitute for chemical chelator desferal in iron-overloaded mice. European journal of pharmacology. 2023 Dec; 960(?):176153. doi: 10.1016/j.ejphar.2023.176153. [PMID: 38059446]
  • Gang Xiang, Wensi Xu, Wenfeng Zhuge, Qing Huang, Cuizhong Zhang, Jinyun Peng. Conductive phthalocyanine-based porous organic polymer as sensing platform for rapid determination of vanillin. The Analyst. 2023 Dec; 148(24):6274-6281. doi: 10.1039/d3an01758c. [PMID: 37969078]
  • Zhi-Qiang Wei, Ji-Xiang Wang, Jin-Meng Guo, Xiao-Long Liu, Qi Yan, Jin Zhang, Shuang-Lin Dong. An odorant receptor tuned to an attractive plant volatile vanillin in Spodoptera litura. Pesticide biochemistry and physiology. 2023 Nov; 196(?):105619. doi: 10.1016/j.pestbp.2023.105619. [PMID: 37945255]
  • Fangyi Mei, Hongling Wang, Yuquan Zhang, Mei Zhang, Shuai Zhou, Haiming Shi, Yuanrong Jiang. Development and Validation of a Stable Isotope Dilution Headspace-SPME-GC/MS Method for the Determination of Vanillin in Fragrant Vegetable Oils. Molecules (Basel, Switzerland). 2023 Oct; 28(21):. doi: 10.3390/molecules28217288. [PMID: 37959708]
  • Evamaria Hofmann, Pierre Degot, Didier Touraud, Burkhard König, Werner Kunz. Novel green production of natural-like vanilla extract from curcuminoids. Food chemistry. 2023 Aug; 417(?):135944. doi: 10.1016/j.foodchem.2023.135944. [PMID: 36934704]
  • Ying Liu, Lichao Sun, Yi-Xin Huo, Shuyuan Guo. Strategies for improving the production of bio-based vanillin. Microbial cell factories. 2023 Aug; 22(1):147. doi: 10.1186/s12934-023-02144-9. [PMID: 37543600]
  • Qiaofang Lu, Kunguang Wang, Zhechao Dou, Lina Zhong, Yuanyuan Yao, Yuanmei Zuo. Vanillin in Resistant Tomato Plant Root Exudate Suppresses Meloidogyne incognita Parasitism. Journal of agricultural and food chemistry. 2023 Jun; ?(?):. doi: 10.1021/acs.jafc.3c00661. [PMID: 37386871]
  • Zarmin Iqbal, Ruhul Quds, Riaz Mahmood. Vanillin attenuates CdCl2-induced cytotoxicity in isolated human erythrocytes. Toxicology in vitro : an international journal published in association with BIBRA. 2023 Jun; ?(?):105633. doi: 10.1016/j.tiv.2023.105633. [PMID: 37336463]
  • Jieren Liao, Veronika Lederer, Alba Bardhi, Zhiwei Zou, Timothy D Hoffmann, Guangxin Sun, Chuankui Song, Thomas Hoffmann, Wilfried Schwab. Acceptors and Effectors Alter Substrate Inhibition Kinetics of a Plant Glucosyltransferase NbUGT72AY1 and Its Mutants. International journal of molecular sciences. 2023 May; 24(11):. doi: 10.3390/ijms24119542. [PMID: 37298492]
  • Camila S Freitas, Samira S Santiago, Daniela P Lage, Luciana M R Antinarelli, Fabrício M Oliveira, Danniele L Vale, Vívian T Martins, Lícia N D Magalhaes, Raquel S Bandeira, Fernanda F Ramos, Isabela A G Pereira, Marcelo M de Jesus, Fernanda Ludolf, Grasiele S V Tavares, Adilson V Costa, Rafaela S Ferreira, Elaine S Coimbra, Róbson R Teixeira, Eduardo A F Coelho. In vitro evaluation of antileishmanial activity, mode of action and cellular response induced by vanillin synthetic derivatives against Leishmania species able to cause cutaneous and visceral leishmaniasis. Experimental parasitology. 2023 May; 251(?):108555. doi: 10.1016/j.exppara.2023.108555. [PMID: 37247802]
  • Nicholas J Day, Juan Wang, Carl J Johnston, So-Young Kim, Heather M Olson, Emma L House, Isaac Kwame Attah, Geremy C Clair, Wei-Jun Qian, Matthew D McGraw. Rat bronchoalveolar lavage proteome changes following e-cigarette aerosol exposures. American journal of physiology. Lung cellular and molecular physiology. 2023 05; 324(5):L571-L583. doi: 10.1152/ajplung.00016.2023. [PMID: 36881561]
  • Kandrakonda Yelamanda Rao, Shaik Jeelan Basha, Kallubai Monika, Navya Naidu Gajula, Irla Sivakumar, Sandeep Kumar, Ramakrishna Vadde, Bindu Madhava Reddy Aramati, Rajagopal Subramanyam, Amooru Gangaiah Damu. Development of quinazolinone and vanillin acrylamide hybrids as multi-target directed ligands against Alzheimer's disease and mechanistic insights into their binding with acetylcholinesterase. Journal of biomolecular structure & dynamics. 2023 Apr; ?(?):1-18. doi: 10.1080/07391102.2023.2203255. [PMID: 37098803]
  • Visessakseth So, Philip Poul, Sokunvary Oeung, Pich Srey, Kimchhay Mao, Huykhim Ung, Poliny Eng, Mengkhim Heim, Marnick Srun, Chantha Chheng, Sin Chea, Tarapong Srisongkram, Natthida Weerapreeyakul. Bioactive Compounds, Antioxidant Activities, and HPLC Analysis of Nine Edible Sprouts in Cambodia. Molecules (Basel, Switzerland). 2023 Mar; 28(6):. doi: 10.3390/molecules28062874. [PMID: 36985845]
  • Xiao Han, Jiayan Huang, Jia Lu, Feng He, Fang Wang, Shuangfeng Li, Hao Zhong, Haiyang Yu, Weiling Pu. Active compounds and potential targets of Shuganning injection in the treatment of hepatocellular carcinoma by network pharmacology and in vitro validation. Naunyn-Schmiedeberg's archives of pharmacology. 2023 Mar; ?(?):. doi: 10.1007/s00210-023-02432-6. [PMID: 36869905]
  • Ronivaldo Rodrigues da Silva, Mohammed Anas Zaiter, Maurício Boscolo, Roberto da Silva, Eleni Gomes. Xylose consumption and ethanol production by Pichia guilliermondii and Candida oleophila in the presence of furans, phenolic compounds, and organic acids commonly produced during the pre-treatment of plant biomass. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]. 2023 Feb; ?(?):. doi: 10.1007/s42770-023-00937-z. [PMID: 36826705]
  • A Diamond, S Barnabé, I Desgagné-Penix. Is a spice missing from the recipe? The intra-cellular localization of vanillin biosynthesis needs further investigations. Plant biology (Stuttgart, Germany). 2023 Jan; 25(1):3-7. doi: 10.1111/plb.13465. [PMID: 36066305]
  • Sooyeon Choi, Chae Eun Haam, Eun-Yi Oh, Seonhee Byeon, Soo-Kyoung Choi, Young-Ho Lee. Vanillin Induces Relaxation in Rat Mesenteric Resistance Arteries by Inhibiting Extracellular Ca2+ Influx. Molecules (Basel, Switzerland). 2022 Dec; 28(1):. doi: 10.3390/molecules28010288. [PMID: 36615485]
  • Laura S Bailey, Dilip V Prajapati, Kari B Basso. Optimization of the Sulfo-Phospho-Vanillin Assay for Total Lipid Normalization in Untargeted Quantitative Lipidomic LC-MS/MS Applications. Analytical chemistry. 2022 12; 94(51):17810-17818. doi: 10.1021/acs.analchem.2c03488. [PMID: 36520113]
  • David L Avetyan, Andrey Shatskiy, Markus D Kärkäs, Elena V Stepanova. Scalable total synthesis of natural vanillin-derived glucoside ω-esters. Carbohydrate research. 2022 Dec; 522(?):108683. doi: 10.1016/j.carres.2022.108683. [PMID: 36179617]
  • Siyao Shao, Sufen Zhang, Zhiyang Yu, Qingfu Ye. Accumulation and biotransformation of the novel vanillin-derived pesticide, vanisulfane, in laying hens after dietary exposure. Journal of hazardous materials. 2022 10; 439(?):129677. doi: 10.1016/j.jhazmat.2022.129677. [PMID: 36104905]
  • Jingyu Gou, Yuxi Guo, Huan Liu, Yanni Zhao, Rongjing Zhu, Yue Dang, Nannan Liu, Mengyin Chen, Xuefeng Chen. Process optimization of vanillin production by conversion of ferulic acid by Bacillus megaterium. Journal of the science of food and agriculture. 2022 Oct; 102(13):6047-6061. doi: 10.1002/jsfa.11957. [PMID: 35462414]
  • Dengyue Liu, Runjiang Song, Zengxue Wu, Zhifu Xing, Deyu Hu. Pyrido [1,2-a] Pyrimidinone Mesoionic Compounds Containing Vanillin Moiety: Design, Synthesis, Antibacterial Activity, and Mechanism. Journal of agricultural and food chemistry. 2022 Aug; 70(34):10443-10452. doi: 10.1021/acs.jafc.2c01838. [PMID: 35972464]
  • Hong-Wei He, Fei-Yu Wang, Danyang Zhang, Cai-Yun Chen, Dan Xu, Huan Zhou, Xili Liu, Gong Xu. Discovery of Novel α-Methylene-γ-Butyrolactone Derivatives Containing Vanillin Moieties as Antiviral and Antifungal Agents. Journal of agricultural and food chemistry. 2022 Aug; 70(33):10316-10325. doi: 10.1021/acs.jafc.2c03632. [PMID: 35960686]
  • Sagar S Arya, Binod K Mahto, Meenu S Sengar, James E Rookes, David M Cahill, Sangram K Lenka. Metabolic Engineering of Rice Cells with Vanillin Synthase Gene (VpVAN) to Produce Vanillin. Molecular biotechnology. 2022 Aug; 64(8):861-872. doi: 10.1007/s12033-022-00470-8. [PMID: 35192168]
  • Cody Pinger, Louise Copeman, Michelle Stowell, Bryan Cormack, Corey Fugate, Matthew Rogers. Rapid measurement of total lipids in zooplankton using the sulfo-phospho-vanillin reaction. Analytical methods : advancing methods and applications. 2022 07; 14(27):2665-2672. doi: 10.1039/d2ay00665k. [PMID: 35748590]
  • Abeer S Elsherbiny, Alyaa Galal, Khalid M Ghoneem, Nehal A Salahuddin. Novel chitosan-based nanocomposites as ecofriendly pesticide carriers: Synthesis, root rot inhibition and growth management of tomato plants. Carbohydrate polymers. 2022 Apr; 282(?):119111. doi: 10.1016/j.carbpol.2022.119111. [PMID: 35123746]
  • Siyao Shao, Xi Cheng, Ruonan Zheng, Sufen Zhang, Zhiyang Yu, Haiyan Wang, Wei Wang, Qingfu Ye. Sex-related deposition and metabolism of vanisulfane, a novel vanillin-derived pesticide, in rats and its hepatotoxic and gonadal effects. The Science of the total environment. 2022 Mar; 813(?):152545. doi: 10.1016/j.scitotenv.2021.152545. [PMID: 34952065]
  • Heba A Metwaly, Abdulrahman M El-Eraky, Eman E Ibrahim, Khaled K Kandil, Mohamed A El-Sayed, Nayra M El-Tabakh, Amr M Motawea, Helmi A Ali, Maher Z Jabban, Mona E Mahmoud, Walaa H Abdelfattah, Mohammad A Elmorsy, Amal M H Ghanim. Vanillin attenuates thioacetamide-induced renal assault by direct and indirect mediation of the TGFβ, ERK and Smad signalling pathways in rats. Cell biochemistry and function. 2022 Mar; 40(2):175-188. doi: 10.1002/cbf.3686. [PMID: 35092082]
  • Sabeeha Ali, Manzar Alam, Fatima Khatoon, Urooj Fatima, Abdelbaset Mohamed Elasbali, Mohd Adnan, Asimul Islam, Md Imtaiyaz Hassan, Mejdi Snoussi, Vincenzo De Feo. Natural products can be used in therapeutic management of COVID-19: Probable mechanistic insights. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Mar; 147(?):112658. doi: 10.1016/j.biopha.2022.112658. [PMID: 35066300]
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