lupeone (BioDeep_00000000090)
Secondary id: BioDeep_00000313760
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C30H48O (424.37049579999996)
中文名称: 羽扇烯酮, 羽扇烯酮
谱图信息:
最多检出来源 Viridiplantae(otcml) 31.43%
分子结构信息
SMILES: C=C(C)C1CCC2(C)CCC3(C)C(CCC4C5(C)CCC(=O)C(C)(C)C5CCC43C)C12
InChI: InChI=1S/C30H48O/c1-19(2)20-11-14-27(5)17-18-29(7)21(25(20)27)9-10-23-28(6)15-13-24(31)26(3,4)22(28)12-16-30(23,29)8/h20-23,25H,1,9-18H2,2-8H3
描述信息
Lupenone is a triterpenoid. It has a role as a metabolite. It derives from a hydride of a lupane.
Lupenone is a natural product found in Liatris acidota, Euphorbia larica, and other organisms with data available.
A natural product found in Cupania cinerea.
Lupenone, isolated from Musa basjoo, belongs to lupane type triterpenoids. Lupenone shows various pharmacological activities including anti-inflammatory, anti-virus, anti-diabetes, anti-cancer, improving Chagas disease without major toxicity[1][2].
Lupenone is an orally active lupine-type triterpenoid that can be isolated from Musa basjoo. Lupenone Lupenone plays a role through the PI3K/Akt/mTOR and NF-κB signaling pathways. Lupenone has anti-inflammatory, antiviral, antidiabetic and anticancer activities[1][2][3].
Lupenone, isolated from Musa basjoo, belongs to lupane type triterpenoids. Lupenone shows various pharmacological activities including anti-inflammatory, anti-virus, anti-diabetes, anti-cancer, improving Chagas disease without major toxicity[1][2].
同义名列表
8 个代谢物同义名
(1S,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-1-Isopropyl-3a,5a,5b,8,8,11a-hexamethyl-1,2,3,3a,4,5,5a,5b,6,7,7a,8,11a,11b,12,13,13a,13b-octadecahydro-9H-cyclopenta[a]chrysen-9-one; (1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-2,3,4,5,6,7,7a,10,11,11b,12,13,13a,13b-tetradecahydro-1H-cyclopenta[a]chrysen-9-one; (1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-1-isopropenyl-3a,5a,5b,8,8,11a-hexamethyl-2,3,4,5,6,7,7a,10,11,11b,12,13,13a,13b-tetradecahydro-1H-cyclopenta[a]chrysen-9-one; (1R,3aR,4S,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-1-Isopropenyl-3a,5a,5b,8,8,11a-hexamethyl-eicosahydro-cyclopenta[a]chrysen-9-one; Lup-20(29)-en-3-one; Lup-20(30)-en-3-one; Lupenone; lupeone
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:67823
- KEGG: C16990
- PubChem: 92158
- PubChem: 323075
- Metlin: METLIN71486
- ChEMBL: CHEMBL486393
- MeSH: lupenone
- ChemIDplus: 0001617705
- KNApSAcK: C00019220
- chemspider: 83203
- CAS: 1617-70-5
- medchemexpress: HY-N2590
- PMhub: MS000025534
- MetaboLights: MTBLC67823
- PubChem: 96023476
- NIKKAJI: J82.270A
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
328 个相关的物种来源信息
- 33090 蒲公英: -
- 33090 南沙参: -
- 464037 Festuca argentina: 10.1016/0305-1978(96)00011-7
- 1504337 Festuca hieronymi: 10.1016/0305-1978(96)00011-7
- 159071 Zanthoxylum ailanthoides:
- 68554 Phellodendron amurense:
- 354509 Phellodendron chinense var. glabriusculum: 10.1021/NP030034V
- 697203 Phellodendron amurense var. wilsonii: 10.1021/NP030034V
- 148671 Anadenanthera colubrina: 10.1055/S-2004-818920
- 549434 Zanthoxylum rhoifolium: 10.1016/0305-1978(92)90104-L
- 1504338 Poa huecu: 10.1021/NP50052A040
- 3806 Bauhinia purpurea: 10.1002/JCCS.199700056
- 45164 Muntingia calabura: 10.1016/S0031-9422(03)00112-2
- 705300 Ormosia henryi: 10.1016/J.FITOTE.2011.10.007
- 568080 Erythrophleum fordii: 10.1016/J.BMC.2008.09.021
- 82280 Adenophora wawreana: 10.4268/CJCMM20111611
- 1548366 Piptolepis ericoides: 10.1016/0031-9422(81)85163-1
- 1569394 Eremanthus capitatus: 10.1016/0031-9422(81)85163-1
- 1825850 Monteverdia truncata: 10.1590/S0103-50531999000600017
- 1081520 Monteverdia ilicifolia: 10.1590/S0103-50531999000600017
- 667327 Calophyllum gracilipes: 10.1016/S0040-4039(97)01032-0
- 1136744 Esenbeckia berlandieri: 10.1016/S0305-1978(01)00138-7
- 1924228 Terminalia glabrescens: 10.1590/S0103-50532003000300021
- 317279 Kleinia galpinii: 10.1016/0031-9422(82)85252-7
- 197987 Scaevola spinescens: 10.1055/S-2006-957961
- 261799 Helichrysum retortum: 10.1016/0031-9422(89)80195-5
- 1641247 Achyranthemum paniculatum: 10.1016/0031-9422(89)80195-5
- 434666 Hilliardiella aristata: 10.1016/0031-9422(82)85189-3
- 1548342 Eremanthus glomerulatus:
- 3656 Cucumis melo: 10.1016/0031-9422(82)85222-9
- 2650239 Sapium stylare: 10.1016/0031-9422(93)85112-5
- 318058 Ixeris chinensis: 10.1248/CPB.44.509
- 38847 Euphorbia segetalis:
- 38844 Euphorbia cyparissias:
- 405131 Curio talinoides:
- 500429 Notholaena neglecta: 10.1021/NP50050A009
- 2306984 Neolitsea parvigemma: 10.1002/JCCS.199800018
- 18794 Senecio: 10.1016/S0031-9422(00)81571-X
- 119829 Astragalus mongholicus: 10.1055/S-2006-960221
- 102783 Liatris acidota: 10.1016/0031-9422(83)83036-2
- 1392584 Codonopsis benthamii: 10.1016/0305-1978(95)00082-8
- 103999 Codonopsis lanceolata: 10.1016/0305-1978(95)00082-8
- 1392605 Codonopsis subglobosa: 10.1016/0305-1978(95)00082-8
- 1392102 Adenophora capillaris: 10.1016/0305-1978(95)00082-8
- 1392599 Codonopsis meleagris: 10.1016/0305-1978(95)00082-8
- 1392586 Codonopsis bulleyana: 10.1016/0305-1978(95)00082-8
- 1392587 Codonopsis canescens: 10.1016/0305-1978(95)00082-8
- 1392606 Codonopsis subscaposa: 10.1016/0305-1978(95)00082-8
- 1678352 Codonopsis macrocalyx: 10.1016/0305-1978(95)00082-8
- 942849 Codonopsis clematidea: 10.1016/0305-1978(95)00082-8
- 1392103 Adenophora coelestis: 10.1016/0305-1978(95)00082-8
- 82277 Adenophora potaninii: 10.1016/0305-1978(95)00082-8
- 82279 Adenophora stricta: 10.1016/0305-1978(95)00082-8
- 361368 Adenophora liliifolia: 10.1016/0305-1978(95)00082-8
- 226229 Adenophora pereskiifolia: 10.1016/0305-1978(95)00082-8
- 1392590 Pseudocodon convolvulaceus: 10.1016/0305-1978(95)00082-8
- 1049772 Adenophora lamarckii: 10.1016/0305-1978(95)00082-8
- 86864 Codonopsis pilosula: 10.1016/0305-1978(95)00082-8
- 1392589 Codonopsis chlorocodon: 10.1016/0305-1978(95)00082-8
- 1049783 Codonopsis ussuriensis: 10.1016/0305-1978(95)00082-8
- 226228 Adenophora stenophylla: 10.1016/0305-1978(95)00082-8
- 187270 Adenophora hunanensis: 10.1016/0305-1978(95)00082-8
- 1225674 Derris cuneifolia:
- 346999 Senna siamea: 10.1016/S0031-9422(01)00025-5
- 179690 Joannesia princeps: 10.1016/S0031-9422(96)00777-7
- 1534677 Tephroseris longifolia: 10.1016/S0031-9422(00)86705-9
- 1534674 Tephroseris helenitis: 10.1016/S0031-9422(00)86705-9
- 1225085 Salacia beddomei: 10.1016/0031-9422(95)00424-6
- 693047 Dysoxylum malabaricum:
- 460347 Perezia pilifera: 10.1016/S0031-9422(00)97880-4
- 48244 Discaria chacaye: 10.1016/0031-9422(73)80719-8
- 381101 Senegalia mellifera: 10.1016/J.PHYTOCHEM.2004.03.002
- 115002 Platypodium elegans: 10.1016/S0367-326X(00)00279-3
- 216994 Betula lenta:
- 283122 Glochidion puberum: 10.1016/S0031-9422(00)89705-8
- 1954552 Deguelia amazonica: 10.1016/S0031-9422(00)98664-3
- 131536 Taraxacum japonicum: 10.1248/BPB.22.606
- 212690 Picris hieracioides: 10.1248/CPB.43.1634
- 210371 Albizia schimperiana: 10.1016/S0367-326X(00)00259-8
- 138525 Albizia versicolor: 10.1016/S0367-326X(00)00259-8
- 189254 Synotis nagensium: 10.1021/NP049831Z
- 1200507 Salvia recognita: 10.1016/S0031-9422(97)01056-X
- 1745020 Bishopiella elegans: 10.1016/0031-9422(91)83025-G
- 56065 Pongamia pinnata:
- 1205696 Blainvillea acmella: 10.1016/S0031-9422(00)83115-5
- 268842 Diospyros mollis: 10.1016/S0031-9422(97)01020-0
- 173701 Boswellia sacra: 10.1248/CPB.58.1541
- 165298 Cissus quadrangularis: 10.1016/0031-9422(91)85270-A
- 405109 Senecio crassissimus: 10.1016/S0031-9422(00)84168-0
- 271535 Glochidion zeylanicum: 10.1016/S0031-9422(00)85232-2
- 161271 Stauntonia obovatifoliola: 10.1016/J.PHYTOCHEM.2008.03.004
- 413758 Diospyros maritima:
- 467254 Arctotheca populifolia: 10.1016/0031-9422(90)89036-9
- 259859 Arctotheca calendula: 10.1016/0031-9422(90)89036-9
- 489979 Celastrus hindsii: 10.1248/CPB.48.1079
- 259893 Artemisia argyi: 10.1248/CPB.32.723
- 504179 Croton arboreus: 10.1021/NP030485F
- 3702 Arabidopsis thaliana: 10.1021/OL800389Q
- 171767 Chuquiraga ulicina: 10.1016/S0031-9422(99)00362-3
- 1071199 Pterocarpus santalinus: 10.1016/S0031-9422(00)97131-0
- 1475121 Aglaia rubiginosa: 10.1016/J.PHYMED.2009.10.015
- 107362 Geoffroea decorticans: 10.1016/S0031-9422(98)00277-5
- 268092 Gelasia cretica: 10.1021/NP0103665
- 114282 Cichorium spinosum: 10.1021/JF025848G
- 1128101 Balanophora indica: 10.1016/0031-9422(88)80772-6
- 306504 Aglaia forbesii: 10.1016/J.PHYTOCHEM.2007.06.016
- 540062 Oxyphyllum ulicinum: 10.1016/0031-9422(88)80118-3
- 13422 Chrysanthemum: 10.1016/S0305-1978(98)00070-2
- 268843 Diospyros rhodocalyx: 10.1055/S-2006-958085
- 280743 Haploclathra paniculata: 10.1016/S0031-9422(00)84543-4
- 1233750 Gardenia saxatilis: 10.1016/S0378-8741(03)00261-7
- 2306952 Nassauvia uniflora: 10.1016/S0031-9422(00)89799-X
- 171746 Mutisia acerosa: 10.1016/S0031-9422(00)89799-X
- 482584 Nassauvia pyramidalis: 10.1016/S0031-9422(00)89799-X
- 274428 Echinops niveus: 10.1016/0031-9422(90)85217-4
- 3743 Synsepalum dulcificum: 10.1007/S10600-010-9658-6
- 76149 Plumbago zeylanica: 10.1016/J.FITOTE.2004.03.009
- 1289396 Vellozia declinans: 10.1016/0031-9422(92)80451-J
- 354530 Zanthoxylum schinifolium: 10.5012/BKCS.2010.31.04.1081
- 48872 Sarmienta scandens: 10.1016/S0031-9422(00)97239-X
- 54894 Tipuana tipu: 10.1515/ZNC-2003-3-411
- 254911 Saussurea japonica: 10.1021/NP9603941
- 1685714 Salvia multicaulis: 10.1016/S0031-9422(97)00540-2
- 496634 Leucheria thermarum: 10.1016/0031-9422(89)85056-3
- 1911708 Leucheria hahnii: 10.1016/0031-9422(89)85056-3
- 1031526 Euphorbia larica: 10.1351/PAC198153061101
- 205042 Acacia dealbata: 10.1080/10575639608043247
- 172013 Ceriops decandra: 10.1071/CH05087
- 212879 Euphorbia drupifera: 10.1016/J.FITOTE.2007.02.002
- 3983 Manihot esculenta: 10.1055/S-2003-38488
- 1227256 Proteopsis argentea: 10.1016/0031-9422(81)85165-5
- 1048568 Metalasia capitata: 10.1016/0031-9422(90)83033-W
- 21017 Betula alleghaniensis: 10.1016/S0031-9422(00)97169-3
- 106618 Bruguiera parviflora:
- 354518 Skimmia laureola: 10.1016/0031-9422(88)80473-4
- 189219 Kleinia neriifolia: 10.1515/ZNC-1995-5-617
- 1087772 Euphorbia nicaeensis: 10.1515/ZNC-1988-11-1202
- 3991 Euphorbia characias: 10.1515/ZNC-1988-11-1202
- 38846 Euphorbia peplus: 10.1515/ZNC-1988-11-1202
- 58331 Quercus suber: 10.1021/NP50034A017
- 589132 Diospyros wallichii: 10.1139/V10-084
- 154997 Euphorbia stygiana: 10.1016/S0031-9422(03)00007-4
- 1321791 Campylospermum flavum: 10.1016/S0305-1978(02)00083-2
- 370702 Senegalia gaumeri: 10.1515/ZNC-2002-9-1002
- 2067306 Lepidaploa myriocephala: 10.1016/S0305-1978(02)00079-0
- 106616 Bruguiera cylindrica: 10.1071/CH05010
- 56060 Butea monosperma: 10.4038/JNSFSR.V18I2.8195
- 1561840 Albizia gummifera: 10.1016/S0367-326X(00)00276-8
- 336154 Stenocereus beneckei: 10.1021/NP50085A017
- 268978 Hypericum balearicum: 10.1515/ZNC-1994-5-617
- 943304 Pachira glabra: 10.1590/S0103-50532002000200022
- 62125 Tephrosia villosa: 10.1016/S0031-9422(00)95025-8
- 68554 Phellodendron amurense: 10.1248/CPB.53.1118
- 1442637 Helichrysum anomalum: 10.1016/0031-9422(89)80195-5
- 154997 Euphorbia stygiana: 10.1016/S0031-9422(97)01011-X
- 62125 Tephrosia villosa: 10.1021/NP0302100
- 1954552 Deguelia amazonica: 10.3987/COM-92-6288
- 2651278 Pongamia pinnata var. pinnata: 10.1021/NP030207G
- 34243 Packera streptanthifolia: 10.1016/S0031-9422(00)84168-0
- 54988 Dipteryx alata: 10.3390/MOLECULES15118193
- 85180 Celastrus: 10.1248/CPB.48.1079
- 2918710 Daphne aurantiaca: 10.1021/NP9005053
- 154986 Euphorbia aphylla: 10.1515/ZNC-1988-1-206
- 38847 Euphorbia segetalis: 10.1016/S0031-9422(03)00007-4
- 464037 Festuca argentina: 10.1016/0305-1978(96)00011-7
- 1504337 Festuca hieronymi: 10.1016/0305-1978(96)00011-7
- 159071 Zanthoxylum ailanthoides:
- 68554 Phellodendron amurense:
- 354509 Phellodendron chinense var. glabriusculum: 10.1021/NP030034V
- 697203 Phellodendron amurense var. wilsonii: 10.1021/NP030034V
- 148671 Anadenanthera colubrina: 10.1055/S-2004-818920
- 549434 Zanthoxylum rhoifolium: 10.1016/0305-1978(92)90104-L
- 1504338 Poa huecu: 10.1021/NP50052A040
- 3806 Bauhinia purpurea: 10.1002/JCCS.199700056
- 45164 Muntingia calabura: 10.1016/S0031-9422(03)00112-2
- 705300 Ormosia henryi: 10.1016/J.FITOTE.2011.10.007
- 568080 Erythrophleum fordii: 10.1016/J.BMC.2008.09.021
- 82280 Adenophora wawreana: 10.4268/CJCMM20111611
- 1548366 Piptolepis ericoides: 10.1016/0031-9422(81)85163-1
- 1569394 Eremanthus capitatus: 10.1016/0031-9422(81)85163-1
- 1825850 Monteverdia truncata: 10.1590/S0103-50531999000600017
- 1081520 Monteverdia ilicifolia: 10.1590/S0103-50531999000600017
- 667327 Calophyllum gracilipes: 10.1016/S0040-4039(97)01032-0
- 1136744 Esenbeckia berlandieri: 10.1016/S0305-1978(01)00138-7
- 1924228 Terminalia glabrescens: 10.1590/S0103-50532003000300021
- 317279 Kleinia galpinii: 10.1016/0031-9422(82)85252-7
- 197987 Scaevola spinescens: 10.1055/S-2006-957961
- 261799 Helichrysum retortum: 10.1016/0031-9422(89)80195-5
- 1641247 Achyranthemum paniculatum: 10.1016/0031-9422(89)80195-5
- 434666 Hilliardiella aristata: 10.1016/0031-9422(82)85189-3
- 1548342 Eremanthus glomerulatus:
- 3656 Cucumis melo: 10.1016/0031-9422(82)85222-9
- 2650239 Sapium stylare: 10.1016/0031-9422(93)85112-5
- 318058 Ixeris chinensis: 10.1248/CPB.44.509
- 38847 Euphorbia segetalis:
- 38844 Euphorbia cyparissias:
- 405131 Curio talinoides:
- 500429 Notholaena neglecta: 10.1021/NP50050A009
- 2306984 Neolitsea parvigemma: 10.1002/JCCS.199800018
- 18794 Senecio: 10.1016/S0031-9422(00)81571-X
- 119829 Astragalus mongholicus: 10.1055/S-2006-960221
- 102783 Liatris acidota: 10.1016/0031-9422(83)83036-2
- 1392584 Codonopsis benthamii: 10.1016/0305-1978(95)00082-8
- 103999 Codonopsis lanceolata: 10.1016/0305-1978(95)00082-8
- 1392605 Codonopsis subglobosa: 10.1016/0305-1978(95)00082-8
- 1392102 Adenophora capillaris: 10.1016/0305-1978(95)00082-8
- 1392599 Codonopsis meleagris: 10.1016/0305-1978(95)00082-8
- 1392586 Codonopsis bulleyana: 10.1016/0305-1978(95)00082-8
- 1392587 Codonopsis canescens: 10.1016/0305-1978(95)00082-8
- 1392606 Codonopsis subscaposa: 10.1016/0305-1978(95)00082-8
- 1678352 Codonopsis macrocalyx: 10.1016/0305-1978(95)00082-8
- 942849 Codonopsis clematidea: 10.1016/0305-1978(95)00082-8
- 1392103 Adenophora coelestis: 10.1016/0305-1978(95)00082-8
- 82277 Adenophora potaninii: 10.1016/0305-1978(95)00082-8
- 82279 Adenophora stricta: 10.1016/0305-1978(95)00082-8
- 361368 Adenophora liliifolia: 10.1016/0305-1978(95)00082-8
- 226229 Adenophora pereskiifolia: 10.1016/0305-1978(95)00082-8
- 1392590 Pseudocodon convolvulaceus: 10.1016/0305-1978(95)00082-8
- 1049772 Adenophora lamarckii: 10.1016/0305-1978(95)00082-8
- 86864 Codonopsis pilosula: 10.1016/0305-1978(95)00082-8
- 1392589 Codonopsis chlorocodon: 10.1016/0305-1978(95)00082-8
- 1049783 Codonopsis ussuriensis: 10.1016/0305-1978(95)00082-8
- 226228 Adenophora stenophylla: 10.1016/0305-1978(95)00082-8
- 187270 Adenophora hunanensis: 10.1016/0305-1978(95)00082-8
- 1225674 Derris cuneifolia:
- 346999 Senna siamea: 10.1016/S0031-9422(01)00025-5
- 179690 Joannesia princeps: 10.1016/S0031-9422(96)00777-7
- 1534677 Tephroseris longifolia: 10.1016/S0031-9422(00)86705-9
- 1534674 Tephroseris helenitis: 10.1016/S0031-9422(00)86705-9
- 1225085 Salacia beddomei: 10.1016/0031-9422(95)00424-6
- 693047 Dysoxylum malabaricum:
- 460347 Perezia pilifera: 10.1016/S0031-9422(00)97880-4
- 48244 Discaria chacaye: 10.1016/0031-9422(73)80719-8
- 381101 Senegalia mellifera: 10.1016/J.PHYTOCHEM.2004.03.002
- 115002 Platypodium elegans: 10.1016/S0367-326X(00)00279-3
- 216994 Betula lenta:
- 283122 Glochidion puberum: 10.1016/S0031-9422(00)89705-8
- 1954552 Deguelia amazonica: 10.1016/S0031-9422(00)98664-3
- 131536 Taraxacum japonicum: 10.1248/BPB.22.606
- 212690 Picris hieracioides: 10.1248/CPB.43.1634
- 210371 Albizia schimperiana: 10.1016/S0367-326X(00)00259-8
- 138525 Albizia versicolor: 10.1016/S0367-326X(00)00259-8
- 189254 Synotis nagensium: 10.1021/NP049831Z
- 1200507 Salvia recognita: 10.1016/S0031-9422(97)01056-X
- 1745020 Bishopiella elegans: 10.1016/0031-9422(91)83025-G
- 56065 Pongamia pinnata:
- 1205696 Blainvillea acmella: 10.1016/S0031-9422(00)83115-5
- 268842 Diospyros mollis: 10.1016/S0031-9422(97)01020-0
- 173701 Boswellia sacra: 10.1248/CPB.58.1541
- 165298 Cissus quadrangularis: 10.1016/0031-9422(91)85270-A
- 405109 Senecio crassissimus: 10.1016/S0031-9422(00)84168-0
- 271535 Glochidion zeylanicum: 10.1016/S0031-9422(00)85232-2
- 161271 Stauntonia obovatifoliola: 10.1016/J.PHYTOCHEM.2008.03.004
- 413758 Diospyros maritima:
- 467254 Arctotheca populifolia: 10.1016/0031-9422(90)89036-9
- 259859 Arctotheca calendula: 10.1016/0031-9422(90)89036-9
- 489979 Celastrus hindsii: 10.1248/CPB.48.1079
- 259893 Artemisia argyi: 10.1248/CPB.32.723
- 504179 Croton arboreus: 10.1021/NP030485F
- 3702 Arabidopsis thaliana: 10.1021/OL800389Q
- 171767 Chuquiraga ulicina: 10.1016/S0031-9422(99)00362-3
- 1071199 Pterocarpus santalinus: 10.1016/S0031-9422(00)97131-0
- 1475121 Aglaia rubiginosa: 10.1016/J.PHYMED.2009.10.015
- 107362 Geoffroea decorticans: 10.1016/S0031-9422(98)00277-5
- 268092 Gelasia cretica: 10.1021/NP0103665
- 114282 Cichorium spinosum: 10.1021/JF025848G
- 1128101 Balanophora indica: 10.1016/0031-9422(88)80772-6
- 306504 Aglaia forbesii: 10.1016/J.PHYTOCHEM.2007.06.016
- 540062 Oxyphyllum ulicinum: 10.1016/0031-9422(88)80118-3
- 13422 Chrysanthemum: 10.1016/S0305-1978(98)00070-2
- 268843 Diospyros rhodocalyx: 10.1055/S-2006-958085
- 280743 Haploclathra paniculata: 10.1016/S0031-9422(00)84543-4
- 1233750 Gardenia saxatilis: 10.1016/S0378-8741(03)00261-7
- 2306952 Nassauvia uniflora: 10.1016/S0031-9422(00)89799-X
- 171746 Mutisia acerosa: 10.1016/S0031-9422(00)89799-X
- 482584 Nassauvia pyramidalis: 10.1016/S0031-9422(00)89799-X
- 274428 Echinops niveus: 10.1016/0031-9422(90)85217-4
- 3743 Synsepalum dulcificum: 10.1007/S10600-010-9658-6
- 76149 Plumbago zeylanica: 10.1016/J.FITOTE.2004.03.009
- 1289396 Vellozia declinans: 10.1016/0031-9422(92)80451-J
- 354530 Zanthoxylum schinifolium: 10.5012/BKCS.2010.31.04.1081
- 48872 Sarmienta scandens: 10.1016/S0031-9422(00)97239-X
- 54894 Tipuana tipu: 10.1515/ZNC-2003-3-411
- 254911 Saussurea japonica: 10.1021/NP9603941
- 1685714 Salvia multicaulis: 10.1016/S0031-9422(97)00540-2
- 496634 Leucheria thermarum: 10.1016/0031-9422(89)85056-3
- 1911708 Leucheria hahnii: 10.1016/0031-9422(89)85056-3
- 1031526 Euphorbia larica: 10.1351/PAC198153061101
- 205042 Acacia dealbata: 10.1080/10575639608043247
- 172013 Ceriops decandra: 10.1071/CH05087
- 212879 Euphorbia drupifera: 10.1016/J.FITOTE.2007.02.002
- 3983 Manihot esculenta: 10.1055/S-2003-38488
- 1227256 Proteopsis argentea: 10.1016/0031-9422(81)85165-5
- 1048568 Metalasia capitata: 10.1016/0031-9422(90)83033-W
- 21017 Betula alleghaniensis: 10.1016/S0031-9422(00)97169-3
- 106618 Bruguiera parviflora:
- 354518 Skimmia laureola: 10.1016/0031-9422(88)80473-4
- 189219 Kleinia neriifolia: 10.1515/ZNC-1995-5-617
- 1087772 Euphorbia nicaeensis: 10.1515/ZNC-1988-11-1202
- 3991 Euphorbia characias: 10.1515/ZNC-1988-11-1202
- 38846 Euphorbia peplus: 10.1515/ZNC-1988-11-1202
- 58331 Quercus suber: 10.1021/NP50034A017
- 589132 Diospyros wallichii: 10.1139/V10-084
- 154997 Euphorbia stygiana: 10.1016/S0031-9422(03)00007-4
- 1321791 Campylospermum flavum: 10.1016/S0305-1978(02)00083-2
- 370702 Senegalia gaumeri: 10.1515/ZNC-2002-9-1002
- 2067306 Lepidaploa myriocephala: 10.1016/S0305-1978(02)00079-0
- 106616 Bruguiera cylindrica: 10.1071/CH05010
- 56060 Butea monosperma: 10.4038/JNSFSR.V18I2.8195
- 1561840 Albizia gummifera: 10.1016/S0367-326X(00)00276-8
- 336154 Stenocereus beneckei: 10.1021/NP50085A017
- 268978 Hypericum balearicum: 10.1515/ZNC-1994-5-617
- 943304 Pachira glabra: 10.1590/S0103-50532002000200022
- 62125 Tephrosia villosa: 10.1016/S0031-9422(00)95025-8
- 68554 Phellodendron amurense: 10.1248/CPB.53.1118
- 1442637 Helichrysum anomalum: 10.1016/0031-9422(89)80195-5
- 154997 Euphorbia stygiana: 10.1016/S0031-9422(97)01011-X
- 62125 Tephrosia villosa: 10.1021/NP0302100
- 1954552 Deguelia amazonica: 10.3987/COM-92-6288
- 2651278 Pongamia pinnata var. pinnata: 10.1021/NP030207G
- 34243 Packera streptanthifolia: 10.1016/S0031-9422(00)84168-0
- 54988 Dipteryx alata: 10.3390/MOLECULES15118193
- 85180 Celastrus: 10.1248/CPB.48.1079
- 2918710 Daphne aurantiaca: 10.1021/NP9005053
- 154986 Euphorbia aphylla: 10.1515/ZNC-1988-1-206
- 38847 Euphorbia segetalis: 10.1016/S0031-9422(03)00007-4
- 259893 Artemisia argyi Lévl.et Vant.: -
- 33090 Plants: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Xiangpei Wang, Mei Liu, Xiaofen Li, Mei Zhang, Feng Xu, Hongyun Liu, Hongmei Wu. Utilizing molecular docking and cell validation to explore the potential mechanisms of lupenone attenuating the inflammatory response via NF-κB pathway.
Scientific reports.
2024 01; 14(1):625. doi:
10.1038/s41598-024-51150-3
. [PMID: 38182871] - Hongmei Wu, Feng Xu, Xulong Huang, Xiaofen Li, Piao Yu, Lingling Zhang, Xiaosong Yang, Juan Kong, Cheng Zhen, Xiangpei Wang. Lupenone improves type 2 diabetic nephropathy by regulating NF-κB pathway-mediated inflammation and TGF-β1/Smad/CTGF-associated fibrosis.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2023 Sep; 118(?):154959. doi:
10.1016/j.phymed.2023.154959
. [PMID: 37478684] - Sandip Debnath, Taha Alqahtani, Ali Alqahtani, Hanan M Alharbi, Shopnil Akash. Lupenone, a wonder chemical obtained from Euphorbia segetalis to boost affinity for the transcriptional factor escalating drought-tolerance in Solanum Lycopersicum: A cutting-edge computational biology approach.
PloS one.
2023; 18(11):e0281293. doi:
10.1371/journal.pone.0281293
. [PMID: 37939107] - Feng Xu, Mei Zhang, Hongmei Wu, Yuanmin Wang, Ye Yang, Xiangpei Wang. Study on the mechanism of lupenone for treating type 2 diabetes by integrating pharmacological evaluation and network pharmacology.
Pharmaceutical biology.
2022 Dec; 60(1):997-1010. doi:
10.1080/13880209.2022.2067568
. [PMID: 35635284] - Emanuelle M B M da Silva Landim, Ana Lúcia T G Ruiz, João E de Carvalho, Armando M Pomini, Lindamir H Pastorini, Silvana M Oliveira Santin. Antiproliferative activity and chemical constituents of Lonchocarpus cultratus (Fabaceae).
Natural product research.
2021 Jun; 35(12):2056-2059. doi:
10.1080/14786419.2019.1647427
. [PMID: 31401870] - Ashish Kumar, Vijai K Agnihotri. Phytochemical studies of Jurinea macrocephala roots from Western Himalaya.
Natural product research.
2020 Feb; 34(3):421-424. doi:
10.1080/14786419.2018.1530233
. [PMID: 30499332] - Lía S Valencia-Chan, Isabel García-Cámara, Luis W Torres-Tapia, Rosa E Moo-Puc, Sergio R Peraza-Sánchez. Lupane-Type Triterpenes of Phoradendron vernicosum.
Journal of natural products.
2017 11; 80(11):3038-3042. doi:
10.1021/acs.jnatprod.7b00177
. [PMID: 29120172] - Feng Xu, Hongmei Wu, Yuanmin Wang, Ye Yang, Yuan Gao, Xiangpei Wang. Determination of lupenone and β-sitosterol in Rhizoma Musae by UPLC with DAD and ELSD.
Journal of chromatographic science.
2015 Nov; 53(10):1714-9. doi:
10.1093/chromsci/bmv079
. [PMID: 26126840] - Oliver Callies, Luis M Bedoya, Manuela Beltrán, Alejandro Muñoz, Patricia Obregón Calderón, Alex A Osorio, Ignacio A Jiménez, José Alcamí, Isabel L Bazzocchi. Isolation, Structural Modification, and HIV Inhibition of Pentacyclic Lupane-Type Triterpenoids from Cassine xylocarpa and Maytenus cuzcoina.
Journal of natural products.
2015 May; 78(5):1045-55. doi:
10.1021/np501025r
. [PMID: 25927586] - Panawan Suttiarporn, Watcharapong Chumpolsri, Sugunya Mahatheeranont, Suwaporn Luangkamin, Somsuda Teepsawang, Vijittra Leardkamolkarn. Structures of phytosterols and triterpenoids with potential anti-cancer activity in bran of black non-glutinous rice.
Nutrients.
2015 Mar; 7(3):1672-87. doi:
10.3390/nu7031672
. [PMID: 25756784] - M Punnam Chander, K Vinod Kumar, A N Shriram, P Vijayachari. Anti-leptospiral activities of an endemic plant Glyptopetalum calocarpum (Kurz.) Prain used as a medicinal plant by Nicobarese of Andaman and Nicobar Islands.
Natural product research.
2015; 29(16):1575-7. doi:
10.1080/14786419.2014.985679
. [PMID: 25482276] - Feng Xu, Hongmei Wu, Xiangpei Wang, Ye Yang, Yuanmin Wang, Haibing Qian, Yanyan Zhang. RP-HPLC characterization of lupenone and β-sitosterol in rhizoma musae and evaluation of the anti-diabetic activity of lupenone in diabetic Sprague-Dawley rats.
Molecules (Basel, Switzerland).
2014 Sep; 19(9):14114-27. doi:
10.3390/molecules190914114
. [PMID: 25207716] - L M Ramadhan Al Muqarrabun, Norizan Ahmat, S Ruzaina S Aris, Nurdiana Shamsulrijal, Syarul N Baharum, Rafidah Ahmad, A Rifki Rosandy, M Nazip Suratman, H Takayama. A new sesquiterpenoid from Scaphium macropodum (Miq.) Beumee.
Natural product research.
2014; 28(9):597-605. doi:
10.1080/14786419.2014.886211
. [PMID: 24568340] - Eun-Kyung Ahn, Joa Sub Oh. Lupenone isolated from Adenophora triphylla var. japonica extract inhibits adipogenic differentiation through the downregulation of PPARγ in 3T3-L1 cells.
Phytotherapy research : PTR.
2013 May; 27(5):761-6. doi:
10.1002/ptr.4779
. [PMID: 22848028] - Myra O Villareal, Junkyu Han, Kyoko Matsuyama, Yukiko Sekii, Abderrazek Smaoui, Hideyuki Shigemori, Hiroko Isoda. Lupenone from Erica multiflora leaf extract stimulates melanogenesis in B16 murine melanoma cells through the inhibition of ERK1/2 activation.
Planta medica.
2013 Mar; 79(3-4):236-43. doi:
10.1055/s-0032-1328189
. [PMID: 23408272] - Mélanie Bourjot, Pieter Leyssen, Cécilia Eydoux, Jean-Claude Guillemot, Bruno Canard, Philippe Rasoanaivo, Françoise Guéritte, Marc Litaudon. Chemical constituents of Anacolosa pervilleana and their antiviral activities.
Fitoterapia.
2012 Sep; 83(6):1076-80. doi:
10.1016/j.fitote.2012.05.004
. [PMID: 22613073] - J P Dzoyem, F A Kechia, V Kuete, A C Pieme, C M Akak, J G Tangmouo, P J Lohoue. Phytotoxic, antifungal activities and acute toxicity studies of the crude extract and compounds from Diospyros canaliculata.
Natural product research.
2011 Apr; 25(7):741-9. doi:
10.1080/14786419.2010.531392
. [PMID: 21462073] - Guohui Li, Qingwen Zhang, Yitao Wang. [Chemical constituents from roots of Pueraria lobata].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2010 Dec; 35(23):3156-60. doi:
. [PMID: 21355238]
- Pilar Puebla, Yoko Oshima-Franco, Luiz M Franco, Marcio G Dos Santos, Renata V da Silva, Leandro Rubem-Mauro, Arturo San Feliciano. Chemical constituents of the bark of Dipteryx alata vogel, an active species against Bothrops jararacussu venom.
Molecules (Basel, Switzerland).
2010 Nov; 15(11):8193-204. doi:
10.3390/molecules15118193
. [PMID: 21076386] - Yu-lan Li, Xian Fan, Yong-liang Wang, Yao-lan Li, Shao-yu Xu, Ying-zhou Cen. [Studies on the triterpenoids constituents from Phyllodium elegans].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2010 May; 33(5):720-1. doi:
"
. [PMID: 20873553] - Minkyun Na, Bo Yeon Kim, Hiroyuki Osada, Jong Seog Ahn. Inhibition of protein tyrosine phosphatase 1B by lupeol and lupenone isolated from Sorbus commixta.
Journal of enzyme inhibition and medicinal chemistry.
2009 Aug; 24(4):1056-9. doi:
10.1080/14756360802693312
. [PMID: 19548777] - Tao Jiang, Bao-kang Huang, Qiao-yan Zhang, Ting Han, Han-chen Zheng, Lu-ping Qin. [Studies on chemical constituents of Liriope platyphylla].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2007 Sep; 30(9):1079-81. doi:
"
. [PMID: 18236747] - Shehla Imam, Iqbal Azhar, M Mohtaseemul Hasan, M S Ali, S Waseemuddin Ahmed. Two triterpenes lupanone and lupeol isolated and identified from Tamarindus indica linn.
Pakistan journal of pharmaceutical sciences.
2007 Apr; 20(2):125-7. doi:
"
. [PMID: 17416567] - Shun Yao, Renming Liu, Xuefeng Huang, Lingyi Kong. Preparative isolation and purification of chemical constituents from the root of Adenophora tetraphlla by high-speed counter-current chromatography with evaporative light scattering detection.
Journal of chromatography. A.
2007 Jan; 1139(2):254-62. doi:
10.1016/j.chroma.2006.11.056
. [PMID: 17150224] - Xiao-ya Shang, Shuai Li, Ying-hong Wang, Su-juan Wang, Yong-chun Yang, Jian-gong Shi. [Chemical constitutents of Bauhinia aurea].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2006 Dec; 31(23):1953-5. doi:
"
. [PMID: 17348187] - Zhong Dai, Feng Wang, Gang-Li Wang, Rui-Chao Lin. [Studies on chemical constituents of Balanophora spicata].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2006 Nov; 31(21):1798-800. doi:
"
. [PMID: 17260797] - Lu-xin Chen, Hong-yan Ma, Mian Zhang, Chao-feng Zhang, Zheng-tao Wang. [Studies on constituents in herb of Senecio scandens].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2006 Nov; 31(22):1872-5. doi:
"
. [PMID: 17285987] - Shu-Yun Bao, Wen-Han Lin. [Compounds from marine mangrove plant Bruguiera sexangula var. rhynchopetala].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2006 Jul; 31(14):1168-71. doi:
. [PMID: 17048587]
- J D Wansi, J Wandji, W A F Kamdem, J C Ndom, H E Ngeufa, D D Chiozem, J Chi Shirri, M I Choudhary, N Tsabang, F Tillequin, Z T Fomum. Triterpenoids from Drypetes chevalieri Beille (euphorbiaceae).
Natural product research.
2006 May; 20(6):586-92. doi:
10.1080/14786410500185451
. [PMID: 16835092] - Qing-fei Ji, Wen-han Lin, Jun Li, Wei Li, Koike Kazuo, Nikaido Tamotsu, Hong-zheng Fu. [Chemical investingation of Chinese mangrove Sonneratia apetala II].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2005 Aug; 30(16):1258-60. doi:
. [PMID: 16245903]
- M Mukhlesur Rahman, David Polfreman, Jodie MacGeachan, Alexander I Gray. Antimicrobial activities of Barringtonia acutangula.
Phytotherapy research : PTR.
2005 Jun; 19(6):543-5. doi:
10.1002/ptr.1341
. [PMID: 16114086] - Sabrina Dallavalle, Lalith Jayasinghe, B M M Kumarihamy, Lucio Merlini, Loana Musso, Leonardo Scaglioni. A new 3,4-seco-lupane derivative from Lasianthus gardneri.
Journal of natural products.
2004 May; 67(5):911-3. doi:
10.1021/np030374g
. [PMID: 15165165] - Esperanza J Carcache-Blanco, Young-Hwa Kang, Eun Jung Park, Bao-Ning Su, Leonardus B S Kardono, Soedarsono Riswan, Harry H S Fong, John M Pezzuto, A Douglas Kinghorn. Constituents of the stem bark of Pongamia pinnata with the potential to induce quinone reductase.
Journal of natural products.
2003 Sep; 66(9):1197-202. doi:
10.1021/np030207g
. [PMID: 14510596] - Tian-Shung Wu, Meei-Yu Hsu, Ping-Chung Kuo, B Sreenivasulu, A G Damu, Chung-Ren Su, Chia-Ying Li, Hsien-Chang Chang. Constituents from the leaves of Phellodendron amurense var. wilsonii and their bioactivity.
Journal of natural products.
2003 Sep; 66(9):1207-11. doi:
10.1021/np030034v
. [PMID: 14510598] - C L Cantrell, S G Franzblau, N H Fischer. Antimycobacterial plant terpenoids.
Planta medica.
2001 Nov; 67(8):685-94. doi:
10.1055/s-2001-18365
. [PMID: 11731906] - T Akihisa, J Ogihara, J Kato, K Yasukawa, M Ukiya, S Yamanouchi, K Oishi. Inhibitory effects of triterpenoids and sterols on human immunodeficiency virus-1 reverse transcriptase.
Lipids.
2001 May; 36(5):507-12. doi:
10.1007/s11745-001-0750-4
. [PMID: 11432464] - A Hisham, A Bai, G JayaKumar, M S Nair, Y Fujimoto. Triterpenoids from Dysoxylum malabaricum.
Phytochemistry.
2001 Feb; 56(4):331-4. doi:
10.1016/s0031-9422(00)00413-1
. [PMID: 11249096]