viminalol (BioDeep_00000859723)

Main id: BioDeep_00000001046

 

PANOMIX_OTCML-2023


代谢物信息卡片


(3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a,6b,8a,11,12,14b-Octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-eicosahydro-picen-3-ol

化学式: C30H50O (426.3861)
中文名称: alpha-香树脂醇, α-香树脂醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1C)C)C
InChI: InChI=1S/C30H50O/c1-19-11-14-27(5)17-18-29(7)21(25(27)20(19)2)9-10-23-28(6)15-13-24(31)26(3,4)22(28)12-16-30(23,29)8/h9,19-20,22-25,31H,10-18H2,1-8H3/t19-,20+,22+,23-,24+,25+,27-,28+,29-,30-/m1/s1

描述信息

Alpha-amyrin is a pentacyclic triterpenoid that is ursane which contains a double bond between positions 12 and 13 and in which the hydrogen at the 3beta position is substituted by a hydroxy group. It is a pentacyclic triterpenoid and a secondary alcohol. It derives from a hydride of an ursane.
alpha-Amyrin is a natural product found in Ficus septica, Ficus virens, and other organisms with data available.
See also: Calendula Officinalis Flower (part of); Viburnum opulus bark (part of); Eupatorium perfoliatum whole (part of) ... View More ...

同义名列表

40 个代谢物同义名

(3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a,6b,8a,11,12,14b-Octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-eicosahydro-picen-3-ol; (3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a,6b,8a,11,12,14b-octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-ol; (3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a,6b,8a,11,12,14b-octamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picen-3-ol; 4,4,6a,6b,8a,11,12,14b-octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-ol; alpha-Amyrin, analytical standard; 3.BETA.-HYDROXYURS-12-ENE; 5alpha-urs-12-en-3beta-ol; (3.beta.)-Urs-12-en-3-ol; Urs-12-en-3-ol, (3beta)-; amyrin, (3alpha)-isomer; 3beta-HYDROXYURS-12-ENE; (3beta)-urs-12-en-3-ol; Urs-12-en-3-ol, (3b)-; .ALPHA.-AMYRIN [MI]; urs-12-ene-3beta-ol; Urs-12-en-3beta-ol; .alpha.-Amyrenol; UNII-30ZAG40J8N; AMYRIN, ALPHA-; alpha-amyrenol; alpha-Amyrine; alpha -Amyrin; alpha-Amyrin; alfa-Amyrin; 30ZAG40J8N; viminalol; a-amyrin; α-Amyrin; Urs-12-en-3-ol, (3beta)- (9CI); EINECS 211-352-1; LMPR01060011; AIDS-070313; 53017_FLUKA; NSC 114787; AIDS070313; ST5411384; 638-95-9; C08615; alpha-Amyrin; alpha-Amyrin



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

463 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 AKT1, ALOX5, CASP3, CAT, PPARG, PTGS1, PTGS2, TYR, XDH
Peripheral membrane protein 5 ACHE, ALOX5, CYP1B1, PTGS1, PTGS2
Endoplasmic reticulum membrane 4 CYP1B1, PTGS1, PTGS2, RAC2
Nucleus 5 ACHE, AKT1, CASP3, PPARA, PPARG
cytosol 9 AKT1, ALOX5, CASP3, CAT, GPT, PPARG, PRKCQ, RAC2, XDH
nucleoplasm 5 AKT1, ALOX5, CASP3, PPARA, PPARG
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 3 ACHE, AKT1, TNF
lamellipodium 2 AKT1, RAC2
Synapse 1 ACHE
cell cortex 1 AKT1
cell surface 2 ACHE, TNF
glutamatergic synapse 2 AKT1, CASP3
Golgi apparatus 2 ACHE, PTGS1
Golgi membrane 1 INS
lysosomal membrane 1 GAA
neuromuscular junction 1 ACHE
neuronal cell body 2 CASP3, TNF
postsynapse 1 AKT1
Cytoplasm, cytosol 1 ALOX5
Lysosome 2 GAA, TYR
plasma membrane 7 ACHE, AKT1, BCHE, GAA, PRKCQ, RAC2, TNF
Membrane 5 ACHE, AKT1, CAT, CYP1B1, GAA
caveola 1 PTGS2
extracellular exosome 5 CAT, GAA, GPT, PTGS1, RAC2
Lysosome membrane 1 GAA
endoplasmic reticulum 1 PTGS2
extracellular space 7 ACHE, ALOX5, BCHE, IL6, INS, TNF, XDH
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 4 ACHE, ALOX5, PPARG, TYR
mitochondrion 2 CAT, CYP1B1
protein-containing complex 3 AKT1, CAT, PTGS2
intracellular membrane-bounded organelle 6 CAT, CYP1B1, GAA, PPARG, PTGS1, TYR
Microsome membrane 3 CYP1B1, PTGS1, PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 TYR
Secreted 5 ACHE, BCHE, GAA, IL6, INS
extracellular region 8 ACHE, ALOX5, BCHE, CAT, GAA, IL6, INS, TNF
mitochondrial outer membrane 1 RAC2
mitochondrial matrix 1 CAT
Extracellular side 1 ACHE
centriolar satellite 1 PRKCQ
photoreceptor outer segment 1 PTGS1
Nucleus membrane 1 ALOX5
nuclear membrane 1 ALOX5
external side of plasma membrane 1 TNF
microtubule cytoskeleton 1 AKT1
Melanosome membrane 1 TYR
cell-cell junction 1 AKT1
Golgi-associated vesicle 1 TYR
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Cytoplasm, perinuclear region 1 ALOX5
Membrane raft 1 TNF
focal adhesion 2 CAT, RAC2
spindle 1 AKT1
Peroxisome 2 CAT, XDH
basement membrane 1 ACHE
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
receptor complex 1 PPARG
neuron projection 2 PTGS1, PTGS2
ciliary basal body 1 AKT1
chromatin 2 PPARA, PPARG
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 RAC2
blood microparticle 1 BCHE
Lipid-anchor, GPI-anchor 1 ACHE
nuclear envelope 2 ALOX5, RAC2
Nucleus envelope 1 ALOX5
Endomembrane system 1 PTGS1
endosome lumen 1 INS
tertiary granule membrane 1 GAA
Melanosome 1 TYR
side of membrane 1 ACHE
ficolin-1-rich granule lumen 2 ALOX5, CAT
secretory granule lumen 3 ALOX5, CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 BCHE, IL6, INS, PTGS2
nuclear matrix 1 ALOX5
transport vesicle 1 INS
azurophil granule membrane 1 GAA
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
Nucleus matrix 1 ALOX5
nuclear envelope lumen 2 ALOX5, BCHE
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 GAA
death-inducing signaling complex 1 CASP3
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
NADPH oxidase complex 1 RAC2
interleukin-6 receptor complex 1 IL6
Nucleus intermembrane space 1 ALOX5
autolysosome lumen 1 GAA
[Isoform H]: Cell membrane 1 ACHE
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Noha Mokhtar Abd-El-Aziz, Mohamed Saeed Hifnawy, Rehab Ahmed Lotfy, Inas Youssef Younis. LC/MS/MS and GC/MS/MS metabolic profiling of Leontodon hispidulus, in vitro and in silico anticancer activity evaluation targeting hexokinase 2 enzyme. Scientific reports. 2024 03; 14(1):6872. doi: 10.1038/s41598-024-57288-4. [PMID: 38519553]
  • Han-Bin Choi, Sangrea Shim, Myeong-Hyeon Wang, Yong-Eui Choi. De Novo Transcriptome Sequencing of Codonopsis lanceolata for Identification of Triterpene Synthase and Triterpene Acetyltransferase. International journal of molecular sciences. 2023 Mar; 24(6):. doi: 10.3390/ijms24065769. [PMID: 36982844]
  • Tran Duc Viet, Tran Dang Xuan, La Hoang Anh. α-Amyrin and β-Amyrin Isolated from Celastrus hindsii Leaves and Their Antioxidant, Anti-Xanthine Oxidase, and Anti-Tyrosinase Potentials. Molecules (Basel, Switzerland). 2021 Nov; 26(23):. doi: 10.3390/molecules26237248. [PMID: 34885832]
  • Bruna F Mazzeu, Tatiana M Souza-Moreira, Andrew A Oliveira, Melissa Remlinger, Lidiane G Felippe, Sandro R Valentini, Rafael V C Guido, Cleslei F Zanelli, Maysa Furlan. The Methionine 549 and Leucine 552 Residues of Friedelin Synthase from Maytenus ilicifolia Are Important for Substrate Binding Specificity. Molecules (Basel, Switzerland). 2021 Nov; 26(22):. doi: 10.3390/molecules26226806. [PMID: 34833897]
  • Jiawei Zhou, Tianyuan Hu, Yuan Liu, Lichan Tu, Yadi Song, Yun Lu, Yifeng Zhang, Yuru Tong, Yujun Zhao, Ping Su, Xiaoyi Wu, Luqi Huang, Wei Gao. Cytochrome P450 catalyses the 29-carboxyl group formation of celastrol. Phytochemistry. 2021 Oct; 190(?):112868. doi: 10.1016/j.phytochem.2021.112868. [PMID: 34273756]
  • María Antonela Zígolo, Matías Rivero Goytia, Hugo Ramiro Poma, Verónica Beatriz Rajal, Verónica Patricia Irazusta. Virtual screening of plant-derived compounds against SARS-CoV-2 viral proteins using computational tools. The Science of the total environment. 2021 Aug; 781(?):146400. doi: 10.1016/j.scitotenv.2021.146400. [PMID: 33794459]
  • Gabriele Vilkickyte, Lina Raudone. Optimization, Validation and Application of HPLC-PDA Methods for Quantification of Triterpenoids in Vaccinium vitis-idaea L. Molecules (Basel, Switzerland). 2021 Mar; 26(6):. doi: 10.3390/molecules26061645. [PMID: 33809511]
  • Alberto Asteggiano, Andrea Occhipinti, Andrea Capuzzo, Enrica Mecarelli, Riccardo Aigotti, Claudio Medana. Quali-Quantitative Characterization of Volatile and Non-Volatile Compounds in Protium heptaphyllum (Aubl.) Marchand Resin by GC-MS Validated Method, GC-FID and HPLC-HRMS2. Molecules (Basel, Switzerland). 2021 Mar; 26(5):. doi: 10.3390/molecules26051447. [PMID: 33800018]
  • Jiaming Wang, Mei Jin, Chunshi Jin, Chao Ye, Yi Zhou, Rongshen Wang, Huanhuan Cui, Wei Zhou, Gao Li. A new pentacyclic triterpenoid from the leaves of Rhododendron dauricum L. with inhibition of NO production in LPS-induced RAW 264.7 cells. Natural product research. 2020 Dec; 34(23):3313-3319. doi: 10.1080/14786419.2019.1566822. [PMID: 30810367]
  • Feilong Chen, Dong-Li Liu, Wei Wang, Xiao-Man Lv, Weixi Li, Li-Dong Shao, Wen-Jing Wang. Bioactive triterpenoids from Sambucus javanica Blume. Natural product research. 2020 Oct; 34(19):2816-2821. doi: 10.1080/14786419.2019.1596092. [PMID: 30968700]
  • Derya Bakir, Mehmet Akdeniz, Abdulselam Ertas, Mustafa A Yilmaz, Ismail Yener, Mehmet Firat, Ufuk Kolak. A GC-MS method validation for quantitative investigation of some chemical markers in Salvia hypargeia Fisch. & C.A. Mey. of Turkey: Enzyme inhibitory potential of ferruginol. Journal of food biochemistry. 2020 09; 44(9):e13350. doi: 10.1111/jfbc.13350. [PMID: 32686189]
  • Jian Wang, Hui-Xin Lin, Huan Zhao, Juan Guo, Ping Su, Jian Yang, Xiao-Yi Wu, Lu-Qi Huang, Wei Gao. Molecular cloning and functional characterization of multiple ApOSCs from Andrographis paniculata. Chinese journal of natural medicines. 2020 Sep; 18(9):659-665. doi: 10.1016/s1875-5364(20)60004-8. [PMID: 32928509]
  • Bruna Karen Cardoso, Herika Line Marko de Oliveira, Ulisses Zonta Melo, Carla Maria Mariano Fernandez, Caio Franco de Araújo Almeida Campo, José Eduardo Gonçalves, Antônio Laverde, Mariza Barion Romagnolo, Giani Andrea Linde, Zilda Cristiani Gazim. Antioxidant activity of α and β-amyrin isolated from Myrcianthes pungens leaves. Natural product research. 2020 Jun; 34(12):1777-1781. doi: 10.1080/14786419.2018.1525715. [PMID: 30465617]
  • Emmanuel Mfotie Njoya, Hermine L D Maza, Pierre Mkounga, Ulrich Koert, Augustin E Nkengfack, Lyndy J McGaw. Selective cytotoxic activity of isolated compounds from Globimetula dinklagei and Phragmanthera capitata (Loranthaceae). Zeitschrift fur Naturforschung. C, Journal of biosciences. 2020 May; 75(5-6):135-144. doi: 10.1515/znc-2019-0171. [PMID: 32229684]
  • Pisanee Srisawat, Ery Odette Fukushima, Shuhei Yasumoto, Jekson Robertlee, Hideyuki Suzuki, Hikaru Seki, Toshiya Muranaka. Identification of oxidosqualene cyclases from the medicinal legume tree Bauhinia forficata: a step toward discovering preponderant α-amyrin-producing activity. The New phytologist. 2019 10; 224(1):352-366. doi: 10.1111/nph.16013. [PMID: 31230357]
  • Zhixue Wu, Hui Xu, Meiling Wang, Ruoting Zhan, Weiwen Chen, Ren Zhang, Zaoyuan Kuang, Fengxue Zhang, Kui Wang, Jiangyong Gu. Molecular Docking and Molecular Dynamics Studies on Selective Synthesis of α-Amyrin and β-Amyrin by Oxidosqualene Cyclases from Ilex Asprella. International journal of molecular sciences. 2019 Jul; 20(14):. doi: 10.3390/ijms20143469. [PMID: 31311103]
  • Juan Xiong, Jiang Wan, Jie Ding, Pei-Pei Wang, Guang-Lei Ma, Jia Li, Jin-Feng Hu. Camellianols A-G, Barrigenol-like Triterpenoids with PTP1B Inhibitory Effects from the Endangered Ornamental Plant Camellia crapnelliana. Journal of natural products. 2017 11; 80(11):2874-2882. doi: 10.1021/acs.jnatprod.7b00241. [PMID: 29064696]
  • Thanh Tra Nguyen, Bich Ngan Truong, Huong Doan Thi Mai, Marc Litaudon, Van Hung Nguyen, Thao Do Thi, Van Minh Chau, Van Cuong Pham. Cytotoxic dammarane-type triterpenoids from the leaves of Viburnum sambucinum. Bioorganic & medicinal chemistry letters. 2017 04; 27(8):1665-1669. doi: 10.1016/j.bmcl.2017.03.014. [PMID: 28318944]
  • Jaeyoung Kwon, Nguyen Tuan Hiep, Dong-Woo Kim, Sungeun Hong, Yuanqiang Guo, Bang Yeon Hwang, Hak Ju Lee, Woongchon Mar, Dongho Lee. Chemical Constituents Isolated from the Root Bark of Cudrania tricuspidata and Their Potential Neuroprotective Effects. Journal of natural products. 2016 08; 79(8):1938-51. doi: 10.1021/acs.jnatprod.6b00204. [PMID: 27420919]
  • Patrícia de Brum Vieira, Nícolas Luiz Feijó Silva, Gloria Narjara Santos da Silva, Denise Brentan Silva, Norberto Peporine Lopes, Simone Cristina Baggio Gnoatto, Márcia Vanusa da Silva, Alexandre José Macedo, Jaume Bastida, Tiana Tasca. Caatinga plants: Natural and semi-synthetic compounds potentially active against Trichomonas vaginalis. Bioorganic & medicinal chemistry letters. 2016 May; 26(9):2229-36. doi: 10.1016/j.bmcl.2016.03.061. [PMID: 27020521]
  • Lili Huang, Jia Li, Hechun Ye, Changfu Li, Hong Wang, Benye Liu, Yansheng Zhang. Molecular characterization of the pentacyclic triterpenoid biosynthetic pathway in Catharanthus roseus. Planta. 2012 Nov; 236(5):1571-81. doi: 10.1007/s00425-012-1712-0. [PMID: 22837051]
  • Xia Li, Junying Zhang, Wenyuan Gao, Haiyang Wang. Study on chemical composition, anti-inflammatory and anti-microbial activities of extracts from Chinese pear fruit (Pyrus bretschneideri Rehd.). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2012 Oct; 50(10):3673-9. doi: 10.1016/j.fct.2012.07.019. [PMID: 22824088]
  • Cesar A Silva, Luiz A S Madureira. Source correlation of biomarkers in a mangrove ecosystem on Santa Catarina Island in southern Brazil. Anais da Academia Brasileira de Ciencias. 2012 Sep; 84(3):589-604. doi: 10.1590/s0001-37652012005000042. [PMID: 22782538]
  • A C Siani, M J Nakamura, M R R Tappin, S S Monteiro, A C Guimarães, M F S Ramos. Chemical composition of South American Burseraceae non-volatile oleoresins and preliminary solubility assessment of their commercial blend. Phytochemical analysis : PCA. 2012 Sep; 23(5):529-39. doi: 10.1002/pca.2351. [PMID: 22323110]
  • Anna Szakiel, Cezary Pączkowski, Heini Koivuniemi, Satu Huttunen. Comparison of the triterpenoid content of berries and leaves of lingonberry Vaccinium vitis-idaea from Finland and Poland. Journal of agricultural and food chemistry. 2012 May; 60(19):4994-5002. doi: 10.1021/jf300375b. [PMID: 22490120]
  • Baiquan Chen, Qian Zhang, Wei Wang, Huan Huang, Wenyi Kang. [Alpha-glucosidase inhibitory active constituents contained in nutshell of Trapa acornis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2012 May; 37(10):1408-11. doi: . [PMID: 22860451]
  • Maha M Salama, Zeinab A Kandil, Wafaa T Islam. Cytotoxic compounds from the leaves of Gaillardia aristata Pursh. growing in Egypt. Natural product research. 2012; 26(22):2057-62. doi: 10.1080/14786419.2011.606219. [PMID: 21846263]
  • Shahira M Ezzat, Hossam M Abdallah, Ghada A Fawzy, Shohda A El-Maraghy. Hepatoprotective constituents of Torilis radiata Moench (Apiaceae). Natural product research. 2012; 26(3):282-5. doi: 10.1080/14786419.2011.587422. [PMID: 21867456]
  • Consolacion Y Ragasa, Dinah L Espineli, Chien-Chang Shen. A new triterpene from Barringtonia asiatica. Natural product research. 2012; 26(20):1869-75. doi: 10.1080/14786419.2011.619187. [PMID: 21929282]
  • Edyta Biskup, Marek Gołębiowski, Robert Gniadecki, Piotr Stepnowski, Ewa Łojkowska. Triterpenoid α-amyrin stimulates proliferation of human keratinocytes but does not protect them against UVB damage. Acta biochimica Polonica. 2012; 59(2):255-60. doi: . [PMID: 22577623]
  • Garland More, Namrita Lall, Ahmed Hussein, Thilivhali Emmanuel Tshikalange. Antimicrobial Constituents of Artemisia afra Jacq. ex Willd. against Periodontal Pathogens. Evidence-based complementary and alternative medicine : eCAM. 2012; 2012(?):252758. doi: 10.1155/2012/252758. [PMID: 22693528]
  • Laís Goyos Pieroni, Fernanda Mendes de Rezende, Valdecir Farias Ximenes, Anne Lígia Dokkedal. Antioxidant activity and total phenols from the methanolic extract of Miconia albicans (Sw.) Triana leaves. Molecules (Basel, Switzerland). 2011 Nov; 16(11):9439-50. doi: 10.3390/molecules16119439. [PMID: 22075573]
  • Navneet B Gadge, Sunil S Jalalpure. Natriuretic and saluretic effects of Hemidesmus indicus R. Br. root extracts in rats. Indian journal of pharmacology. 2011 Nov; 43(6):714-7. doi: 10.4103/0253-7613.89833. [PMID: 22144781]
  • Cyril Brendolise, Yar-Khing Yauk, Ellen D Eberhard, Mindy Wang, David Chagne, Christelle Andre, David R Greenwood, Lesley L Beuning. An unusual plant triterpene synthase with predominant α-amyrin-producing activity identified by characterizing oxidosqualene cyclases from Malus × domestica. The FEBS journal. 2011 Jul; 278(14):2485-99. doi: 10.1111/j.1742-4658.2011.08175.x. [PMID: 21575133]
  • Chun-ying Xie, Le-wei Lin. [Study on the chemical constituents of Pithecellobium clypearia]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2011 Jul; 34(7):1060-2. doi: . [PMID: 22066399]
  • Jianhong Ching, Hai-Shu Lin, Chay-Hoon Tan, Hwee-Ling Koh. Quantification of α- and β-amyrin in rat plasma by gas chromatography-mass spectrometry: application to preclinical pharmacokinetic study. Journal of mass spectrometry : JMS. 2011 May; 46(5):457-64. doi: 10.1002/jms.1912. [PMID: 21500304]
  • Taha S El-Alfy, Shahira M Ezzat, Ahmed K Hegazy, Aziza M M Amer, Gehan M Kamel. Isolation of biologically active constituents from Moringa peregrina (Forssk.) Fiori. (family: Moringaceae) growing in Egypt. Pharmacognosy magazine. 2011 Apr; 7(26):109-15. doi: 10.4103/0973-1296.80667. [PMID: 21716619]
  • D D Duan, C Y Bu, J Cheng, Y N Wang, G L Shi. Isolation and identification of acaricidal compounds in Inula japonica (Asteraceae). Journal of economic entomology. 2011 Apr; 104(2):375-8. doi: 10.1603/ec10129. [PMID: 21510182]
  • Rajnish Gupta, Jai B S Kachhawa, R S Gupta, Anil Kumar Sharma, M C Sharma, M P Dobhal. Phytochemical evaluation and antispermatogenic activity of Thevetia peruviana methanol extract in male albino rats. Human fertility (Cambridge, England). 2011 Mar; 14(1):53-9. doi: 10.3109/14647273.2010.542230. [PMID: 21466267]
  • Feng Wang, Zhan-Lin Li, Hong-Hua Cui, Hui-Ming Hua, Yong-Kui Jing, Sheng-Wang Liang. Two new triterpenoids from the resin of Boswellia carterii. Journal of Asian natural products research. 2011 Mar; 13(3):193-7. doi: 10.1080/10286020.2010.548808. [PMID: 21409679]
  • Ali M El-Hagrassi, Mamdouh M Ali, Abeer F Osman, Mohamed Shaaban. Phytochemical investigation and biological studies of Bombax malabaricum flowers. Natural product research. 2011 Jan; 25(2):141-51. doi: 10.1080/14786419.2010.518146. [PMID: 21246441]
  • Bertin Vouffo, Etienne Dongo, Petrea Facey, Andrea Thorn, George Sheldrick, Armin Maier, Heinz Herbert Fiebig, Hartmut Laatsch. Antiarol cinnamate and africanoside, a cinnamoyl triterpene and a hydroperoxy-cardenolide from the stem bark of Antiaris africana. Planta medica. 2010 Oct; 76(15):1717-23. doi: 10.1055/s-0030-1249958. [PMID: 20533166]
  • Hasnah M Sirat, Deny Susanti, Farediah Ahmad, Hiromitsu Takayama, Mariko Kitajima. Amides, triterpene and flavonoids from the leaves of Melastoma malabathricum L. Journal of natural medicines. 2010 Oct; 64(4):492-5. doi: 10.1007/s11418-010-0431-8. [PMID: 20582481]
  • Delcio Dias Marques, Ilmar Bernardo Graebner, Telma Leda Gomes de Lemos, Luciana Lucas Machado, Jõao Carlos Costa Assunção, Francisco José Queiroz Monte. Triterpenes from Protium hebetatum resin. Natural product communications. 2010 Aug; 5(8):1181-2. doi: . [PMID: 20839613]
  • Chuang Liu, Kun Zou, Zhiyong Guo, Yuying Zhao, Fan Cheng, Hongqi Zhang. [Chemical constituents from leaves of Boehmeria nivea]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2010 Jun; 35(11):1432-4. doi: 10.4268/cjcmm20101116. [PMID: 20822015]
  • Sheng Lin, Zhongxiao Zhanf, Yunheng Shen, Huiliang Li, Lei Shan, Runhui Liu, Xike Xu, Weidong Zhanf. [Ethyl acetate-soluble chemical constituents from whole plants of Senecio chrysanthemoides]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2010 May; 35(9):1137-41. doi: 10.4268/cjcmm20100911. [PMID: 20707068]
  • Ping Wang, Stacy Ownby, Zhizhen Zhang, Wei Yuan, Shiyou Li. Cytotoxicity and inhibition of DNA topoisomerase I of polyhydroxylated triterpenoids and triterpenoid glycosides. Bioorganic & medicinal chemistry letters. 2010 May; 20(9):2790-6. doi: 10.1016/j.bmcl.2010.03.063. [PMID: 20371180]
  • Ds Reddy, Is Muchandi, Ra Srinivasa, Ha Pradeep, K Ravikumar, Ms Rao, M Ibrahim. Effect of Holostemma annularis on the progression of diabetes induced by a high fructose diet in rats and in diabetic C57BL/6J ob/ob mice. Diabetes, metabolic syndrome and obesity : targets and therapy. 2010 Apr; 3(?):87-94. doi: NULL. [PMID: 21437079]
  • J S Ashidi, P J Houghton, P J Hylands, T Efferth. Ethnobotanical survey and cytotoxicity testing of plants of South-western Nigeria used to treat cancer, with isolation of cytotoxic constituents from Cajanus cajan Millsp. leaves. Journal of ethnopharmacology. 2010 Mar; 128(2):501-12. doi: 10.1016/j.jep.2010.01.009. [PMID: 20064598]
  • Liliana Hernandez-Vazquez, Mercedes Bonfill, Elisabeth Moyano, Rosa M Cusido, Arturo Navarro-Ocaña, Javier Palazon. Conversion of alpha-amyrin into centellosides by plant cell cultures of Centella asiatica. Biotechnology letters. 2010 Feb; 32(2):315-9. doi: 10.1007/s10529-009-0143-x. [PMID: 19838635]
  • Florence Brüll, Ronald P Mensink, Karin van den Hurk, Adriaan Duijvestijn, Jogchum Plat. TLR2 activation is essential to induce a Th1 shift in human peripheral blood mononuclear cells by plant stanols and plant sterols. The Journal of biological chemistry. 2010 Jan; 285(5):2951-8. doi: 10.1074/jbc.m109.036343. [PMID: 19948716]
  • Shao-Hui Zhu, Qian-Jun Zhang, Qing Chen, Tuo Zhou, Rong-Jun Yao. [Study on the chemical constituents of Dichrocephala integrifolia]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2010 Jan; 33(1):53-5. doi: . [PMID: 20518304]
  • Toshihiro Akihisa, Nobuo Kojima, Naoko Katoh, Yuki Ichimura, Hirohisa Suzuki, Makoto Fukatsu, Steven Maranz, Eliot T Masters. Triterpene alcohol and fatty acid composition of shea nuts from seven African countries. Journal of oleo science. 2010; 59(7):351-60. doi: 10.5650/jos.59.351. [PMID: 20513968]
  • Ill-Min Chung, Min-Young Kim, Sun-Dong Park, Won-Hwan Park, Hyung-In Moon. In vitro evaluation of the antiplasmodial activity of Dendropanax morbifera against chloroquine-sensitive strains of Plasmodium falciparum. Phytotherapy research : PTR. 2009 Nov; 23(11):1634-7. doi: 10.1002/ptr.2838. [PMID: 19367673]
  • Mitja Martelanc, Irena Vovk, Breda Simonovska. Separation and identification of some common isomeric plant triterpenoids by thin-layer chromatography and high-performance liquid chromatography. Journal of chromatography. A. 2009 Sep; 1216(38):6662-70. doi: 10.1016/j.chroma.2009.07.038. [PMID: 19695573]
  • Shen-Chieh Chou, Vivek Krishna, Chang-Hung Chou. Hydrophobic metabolites from Rhododendron formosanum and their allelopathic activities. Natural product communications. 2009 Sep; 4(9):1189-92. doi: . [PMID: 19831026]
  • Christiane Meyre-Silva, Cristiane Maes Petry, Talita Elisa Berté, Renan Gandolfi Becker, Francielle Zanatta, Franco Delle-Monache, Valdir Cechinel-Filho, Sérgio Faloni Andrade. Phytochemical analyses and gastroprotective effects of Eugenia umbelliflora (Myrtaceae) on experimental gastric ulcers. Natural product communications. 2009 Jul; 4(7):911-6. doi: . [PMID: 19731591]
  • Prabir Kumar Chaudhuri, Deepika Singh. A new lipid and other constituents from the rhizomes of Nelumbo nucifera. Journal of Asian natural products research. 2009 Jul; 11(7):583-7. doi: 10.1080/10286020902813957. [PMID: 20183294]
  • M A Ramadan, A S Ahmad, A M Nafady, A I Mansour. Chemical composition of the stem bark and leaves of Ficus pandurata Hance. Natural product research. 2009; 23(13):1218-30. doi: 10.1080/14786410902757899. [PMID: 19731141]
  • Ming-Ming Yan, Da-Qing Zhao, Shuai Shao, Wan-Hui Liu, Sheng-Nan Bi, Hai-Jing Wang. [Studies on the constituents from the herba of Erigeron acer]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2008 Sep; 31(9):1334-6. doi: ". [PMID: 19180951]
  • Phan Van Kiem, Tran Hong Quang, Tran Thu Huong, Le Thi Hong Nhung, Nguyen Xuan Cuong, Chau Van Minh, Eun Mi Choi, Young Ho Kim. Chemical constituents of Acanthus ilicifolius L. and effect on osteoblastic MC3T3E1 cells. Archives of pharmacal research. 2008 Jul; 31(7):823-9. doi: 10.1007/s12272-001-1232-3. [PMID: 18704321]
  • Sung-Jin Lee, Hye Min Kim, Jeong Min Lee, Hee Seung Park, Sanghyun Lee. Artemisterol, a new steryl ester from the whole plant of Artemisia apiacea. Journal of Asian natural products research. 2008 Mar; 10(3-4):313-6. doi: 10.1080/10286020701782486. [PMID: 18348053]
  • M E Carretero, J L López-Pérez, M J Abad, P Bermejo, S Tillet, A Israel, B Noguera-P. Preliminary study of the anti-inflammatory activity of hexane extract and fractions from Bursera simaruba (Linneo) Sarg. (Burseraceae) leaves. Journal of ethnopharmacology. 2008 Feb; 116(1):11-5. doi: 10.1016/j.jep.2007.10.034. [PMID: 18155865]
  • D I Batovska, I T Todorova, V S Bankova, S P Parushev, A I Atanassov, T D Hvarleva, G J Djakova, S S Popov. Seasonal variations in the chemical composition of vine-grape leaf surface. Natural product research. 2008; 22(14):1231-36. doi: 10.1080/14786410701725865. [PMID: 18932086]
  • R C P Lima-Júnior, D I M Sousa, G A C Brito, G M Cunha, M H Chaves, V S N Rao, F A Santos. Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 2007 Dec; 56(12):487-94. doi: 10.1007/s00011-007-7023-4. [PMID: 18210232]
  • Kiyoshi Ohyama, Masashi Suzuki, Kazuo Masuda, Shigeo Yoshida, Toshiya Muranaka. Chemical phenotypes of the hmg1 and hmg2 mutants of Arabidopsis demonstrate the in-planta role of HMG-CoA reductase in triterpene biosynthesis. Chemical & pharmaceutical bulletin. 2007 Oct; 55(10):1518-21. doi: 10.1248/cpb.55.1518. [PMID: 17917299]
  • Guang-Bo Xie, Si-Xiang Zhou, Lian-Di Lei, Peng-Fei Tu. [Studies on triterpenoid constituents in leaf of Ilex pernyi]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2007 Sep; 32(18):1890-2. doi: ". [PMID: 18051898]
  • Sara Hoet, Luc Pieters, Giulio G Muccioli, Jean-Louis Habib-Jiwan, Fred R Opperdoes, Joëlle Quetin-Leclercq. Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds. Journal of natural products. 2007 Aug; 70(8):1360-3. doi: 10.1021/np070038q. [PMID: 17637068]
  • Shuang Liang, Hai-sheng Chen, Yong-sheng Jin, Li Jin, Jia Lu, Jing-ling Du. [Study on chemical constituents in rhigome of Ervatamia hainanensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2007 Jul; 32(13):1296-9. doi: . [PMID: 17879729]
  • Lei Wang, Zhi-qi Yin, Lei-hong Zhang, Wen-cai Ye, Xiao-qi Zhang, Wen-bin Shen, Shou-xun Zhao. [Chemical constituents from root barks of Periploca sepium]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2007 Jul; 32(13):1300-2. doi: . [PMID: 17879730]
  • Ijaz Ahmad, Itrat Anis, Itrat Fatima, Abdul Malik, Shafiullah Khan, Nighat Afza, Rasool Bakhsh Tareen, Muhammad Arif Lodhi, M Iqbal Choudhary. Two new protease-inhibiting glycosphingolipids from Buddleja crispa. Chemistry & biodiversity. 2007 May; 4(5):917-24. doi: 10.1002/cbdv.200790080. [PMID: 17510987]
  • Hiroshi Saimaru, Yutaka Orihara, Pimpimon Tansakul, Young-Hwa Kang, Masaaki Shibuya, Yutaka Ebizuka. Production of triterpene acids by cell suspension cultures of Olea europaea. Chemical & pharmaceutical bulletin. 2007 May; 55(5):784-8. doi: 10.1248/cpb.55.784. [PMID: 17473469]
  • Marcia M L Yu, H Georg Schulze, Reinhard Jetter, Michael W Blades, Robin F B Turner. Raman microspectroscopic analysis of triterpenoids found in plant cuticles. Applied spectroscopy. 2007 Jan; 61(1):32-7. doi: 10.1366/000370207779701352. [PMID: 17311714]
  • Mohammad Basyuni, Hirosuke Oku, Masashi Inafuku, Shigeyuki Baba, Hironori Iwasaki, Keichiro Oshiro, Takafumi Okabe, Masaaki Shibuya, Yutaka Ebizuka. Molecular cloning and functional expression of a multifunctional triterpene synthase cDNA from a mangrove species Kandelia candel (L.) Druce. Phytochemistry. 2006 Dec; 67(23):2517-24. doi: 10.1016/j.phytochem.2006.09.016. [PMID: 17078982]
  • Pu Liu, Hong-quan Duan, Qin Pan, Yan-wen Zhang, Zhi Yao. [Triterpenes from herb of Potentilla chinesis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 Nov; 31(22):1875-9. doi: . [PMID: 17285988]
  • You-Xia Wei, Jun-Xian Wang. [Studies on the chemical constituents of hypogeal part from Limonium bicolor]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2006 Nov; 29(11):1182-4. doi: ". [PMID: 17228660]
  • Eduardo J Crevelin, Isabel C C Turatti, Antonio E M Crotti, Rodrigo C S Veneziani, João L C Lopes, Norberto P Lopes, Wilson R Cunha. Identification of biologically active triterpenes and sterols present in hexane extracts from Miconia species using high-resolution gas chromatography. Biomedical chromatography : BMC. 2006 Aug; 20(8):827-30. doi: 10.1002/bmc.609. [PMID: 16345013]
  • Roberto C P Lima-Júnior, Francisco A Oliveira, Luilma A Gurgel, Italo J Cavalcante, Kelcyana A Santos, Deive A Campos, Cinthia A Vale, Regilane M Silva, Mariana H Chaves, Vietla S N Rao, Flávia A Santos. Attenuation of visceral nociception by alpha- and beta-amyrin, a triterpenoid mixture isolated from the resin of Protium heptaphyllum, in mice. Planta medica. 2006 Jan; 72(1):34-9. doi: 10.1055/s-2005-873150. [PMID: 16450293]
  • Ling-ling Xu, Jie Lu, Wei-jia Li, Ling-yi Kong. [Studies on the chemical constituents in root of Coleus forskohlii]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2005 Nov; 30(22):1753-5. doi: ". [PMID: 16468372]
  • Ortwin Guhling, Christian Kinzler, Michael Dreyer, Gerhard Bringmann, Reinhard Jetter. Surface composition of myrmecophilic plants: cuticular wax and glandular trichomes on leaves of Macaranga tanarius. Journal of chemical ecology. 2005 Oct; 31(10):2323-41. doi: 10.1007/s10886-005-7104-1. [PMID: 16195846]
  • M Venkatesan, M B Viswanathan, N Ramesh, P Lakshmanaperumalsamy. Antibacterial potential from Indian Suregada angustifolia. Journal of ethnopharmacology. 2005 Jul; 99(3):349-52. doi: 10.1016/j.jep.2005.01.029. [PMID: 15878247]
  • Ahmet C Gören, Bing-Nan Zhou, Gülaçti Topçu, Gamze Kökdil, David G I Kingston. DNA damaging activities of methanol extract of Ajuga postii and iridoid glucoside reptoside. Natural product research. 2005 Jul; 19(5):457-60. doi: 10.1080/14786410412331272095. [PMID: 15938192]
  • Barbara Klimek, Daniel Modnicki. Terpenoids and sterols from Nepeta cataria L. var. citriodora (Lamiaceae). Acta poloniae pharmaceutica. 2005 May; 62(3):231-5. doi: ". [PMID: 16193817]
  • Yaling Cai, Jinlang Ruan. [Studies on the chemical constituents from the leaf of Liquidambar formosana Hance]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2005 Apr; 28(4):294-5. doi: ". [PMID: 16104503]
  • Liwei Fu, Shujun Zhang, Na Li, Jinlan Wang, Ming Zhao, Junichi Sakai, Toshiaki Hasegawa, Tomokazu Mitsui, Takao Kataoka, Seiko Oka, Miwa Kiuchi, Katutoshi Hirose, Masayoshi Ando. Three new triterpenes from Nerium oleander and biological activity of the isolated compounds. Journal of natural products. 2005 Feb; 68(2):198-206. doi: 10.1021/np040072u. [PMID: 15730243]
  • Michel F Otuki, Fabiana Vieira-Lima, Angela Malheiros, Rosendo A Yunes, João B Calixto. Topical antiinflammatory effects of the ether extract from Protium kleinii and alpha-amyrin pentacyclic triterpene. European journal of pharmacology. 2005 Jan; 507(1-3):253-9. doi: 10.1016/j.ejphar.2004.11.012. [PMID: 15659316]
  • Piotr Migas, Wojciech Cisowski, Wanda Dembińska-Migas. Isoprene derivatives from the leaves and callus cultures of Vaccinium corymbosum var. bluecrop. Acta poloniae pharmaceutica. 2005 Jan; 62(1):45-51. doi: . [PMID: 16022493]
  • Ademir E do Vale, Jorge M David, Hugo N Brandão, Juceni P David. A new flavonol glycoside derivative from leaves of Moldenhawera nutans. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2005 Jan; 60(1-2):45-9. doi: 10.1515/znc-2005-1-209. [PMID: 15787243]
  • Toshihiro Akihisa, Scott G Franzblau, Motohiko Ukiya, Hiroki Okuda, Fangqiu Zhang, Ken Yasukawa, Takashi Suzuki, Yumiko Kimura. Antitubercular activity of triterpenoids from Asteraceae flowers. Biological & pharmaceutical bulletin. 2005 Jan; 28(1):158-60. doi: 10.1248/bpb.28.158. [PMID: 15635183]
  • Norio Nakamura. [Inhibitory effects of some traditional medicines on proliferation of HIV-1 and its protease]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2004 Aug; 124(8):519-29. doi: 10.1248/yakushi.124.519. [PMID: 15297721]
  • Irene M Villaseñor, Arlyn P Canlas, Karen M Faustino, Katherine G Plana. Evaluation of the bioactivity of triterpene mixture isolated from Carmona retusa (Vahl.) Masam leaves. Journal of ethnopharmacology. 2004 May; 92(1):53-6. doi: 10.1016/j.jep.2004.01.017. [PMID: 15099847]
  • Sebastien Block, Chiara Baccelli, Bernard Tinant, Luc Van Meervelt, Raoul Rozenberg, Jean-Louis Habib Jiwan, Gabriel Llabrès, Marie-Claire De Pauw-Gillet, Joelle Quetin-Leclercq. Diterpenes from the leaves of Croton zambesicus. Phytochemistry. 2004 Apr; 65(8):1165-71. doi: 10.1016/j.phytochem.2004.02.023. [PMID: 15110699]
  • Maria-Teresa Gutierrez-Lugo, Joshua D Deschamps, Theodore R Holman, Enrique Suarez, Barbara N Timmermann. Lipoxygenase inhibition by anadanthoflavone, a new flavonoid from the aerial parts of Anadenanthera colubrina. Planta medica. 2004 Mar; 70(3):263-5. doi: 10.1055/s-2004-818920. [PMID: 15114507]
  • Ana Luisa Anaya, Rachel Mata, James J Sims, Azucena González-Coloma, Rocio Cruz-Ortega, Ana Guadaño, Blanca E Hernández-Bautista, Sharon L Midland, Riselda Ríos, Arturo Gómez-Pompa. Allelochemical potential of Callicarpa acuminata. Journal of chemical ecology. 2003 Dec; 29(12):2761-76. doi: 10.1023/b:joec.0000008019.22063.5c. [PMID: 14969362]
  • Sanghyun Lee, Kyoung Soon Kim, Sang Hee Shim, You Mie Park, Bak-Kwang Kim. Constituents from the non-polar fraction of Artemisia apiacea. Archives of pharmacal research. 2003 Nov; 26(11):902-5. doi: 10.1007/bf02980197. [PMID: 14661854]
  • B Singh, S Singh. Antimicrobial activity of terpenoids from Trichodesma amplexicaule Roth. Phytotherapy research : PTR. 2003 Aug; 17(7):814-6. doi: 10.1002/ptr.1202. [PMID: 12916085]
  • Supinya Tewtrakul, Hirotsugu Miyashiro, Norio Nakamura, Masao Hattori, Takuya Kawahata, Toru Otake, Tomokazu Yoshinaga, Tamio Fujiwara, Tanomjit Supavita, Supreeya Yuenyongsawad, Pranee Rattanasuwon, Sukanya Dej-Adisai. HIV-1 integrase inhibitory substances from Coleus parvifolius. Phytotherapy research : PTR. 2003 Mar; 17(3):232-9. doi: 10.1002/ptr.1111. [PMID: 12672152]
  • M Asif Saeed, A W Sabir. Irritant potential of some constituents from the seeds of Caesalpinia bonducella (L.) fleming. Journal of Asian natural products research. 2003 Mar; 5(1):35-41. doi: 10.1080/1028602031000080441. [PMID: 12608637]
  • Cornelia P Vermeer, Peter Nastold, Reinhard Jetter. Homologous very-long-chain 1,3-alkanediols and 3-hydroxyaldehydes in leaf cuticular waxes of Ricinus communis L. Phytochemistry. 2003 Feb; 62(3):433-8. doi: 10.1016/s0031-9422(02)00560-5. [PMID: 12620356]