Isovitexin (BioDeep_00000000204)

 

Secondary id: BioDeep_00000184981, BioDeep_00000269983, BioDeep_00000400118

human metabolite PANOMIX_OTCML-2023 BioNovoGene_Lab2019 natural product


代谢物信息卡片


5,7-dihydroxy-2-(4-hydroxyphenyl)-6-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one

化学式: C21H20O10 (432.1056)
中文名称: 异牡荆素, 异牡荆黄素
谱图信息: 最多检出来源 Viridiplantae(plant) 23.71%

分子结构信息

SMILES: C1(O)=CC2OC(C3C=CC(O)=CC=3)=CC(=O)C=2C(O)=C1[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1
InChI: InChI=1S/C21H20O10/c22-7-14-17(26)19(28)20(29)21(31-14)16-11(25)6-13-15(18(16)27)10(24)5-12(30-13)8-1-3-9(23)4-2-8/h1-6,14,17,19-23,25-29H,7H2/t14-,17-,19+,20-,21+/m1/s1

描述信息

Isovitexin is a C-glycosyl compound that consists of apigenin substituted by a 1,5-anhydro-D-glucitol moiety at position 6. It has a role as an EC 3.2.1.20 (alpha-glucosidase) inhibitor and a metabolite. It is a C-glycosyl compound and a trihydroxyflavone. It is functionally related to an apigenin. It is a conjugate acid of an isovitexin-7-olate.
Isovitexin is a natural product found in Carex fraseriana, Rauhiella, and other organisms with data available.
See also: Fenugreek seed (part of); Acai (part of); Crataegus monogyna flowering top (part of).
[Raw Data] CBA25_Isovitexin_neg_20eV_1-7_01_1425.txt
[Raw Data] CBA25_Isovitexin_neg_10eV_1-7_01_1369.txt
[Raw Data] CBA25_Isovitexin_pos_30eV_1-7_01_1399.txt
[Raw Data] CBA25_Isovitexin_neg_40eV_1-7_01_1427.txt
[Raw Data] CBA25_Isovitexin_neg_30eV_1-7_01_1426.txt
[Raw Data] CBA25_Isovitexin_neg_50eV_1-7_01_1428.txt
[Raw Data] CBA25_Isovitexin_pos_20eV_1-7_01_1398.txt
[Raw Data] CBA25_Isovitexin_pos_10eV_1-7_01_1358.txt
[Raw Data] CBA25_Isovitexin_pos_40eV_1-7_01_1400.txt
[Raw Data] CBA25_Isovitexin_pos_50eV_1-7_01_1401.txt
Isovitexin is a flavonoid isolated from passion flower, Cannabis and, and the palm, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB.
Isovitexin is a flavonoid isolated from passion flower, Cannabis and, and the palm, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB.

同义名列表

45 个代谢物同义名

5,7-dihydroxy-2-(4-hydroxyphenyl)-6-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]chromen-4-one; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one; (1S)-1,5-anhydro-1-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl]-D-glucitol; 4H-1-Benzopyran-4-one, 6-beta-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)- (VAN); (1S)-1,5-anhydro-1-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl)-D-glucitol; 4H-1-Benzopyran-4-one, 6-.beta.-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 4H-1-Benzopyran-4-one, 6-beta-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 6-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one,6-尾-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-; Ethyl6-amino-5-cyano-2-methyl-4-phenyl-4H-pyran-3-carboxylate; ISOVITEXIN (CONSTITUENT OF HAWTHORN LEAF WITH FLOWER); Isovitexin, primary pharmaceutical reference standard; Flavone, 6-.beta.-D-glucopyranosyl-4,5,7-trihydroxy-; Flavone, 6-beta-D-glucopyranosyl-4,5,7-trihydroxy-; 6-beta-D-Glucopyranosyl-4,5,7-trihydroxyflavone; 6-(beta-D-glucopyranosyl)-2-hydroxynaringenin; 6-C-glucosyl-4,5,7-trihydroxyflavone; 6-C-.BETA.-D-GLUCOPYRANOSYLAPIGENIN; 6-C-beta-D-Glucopyranosylapigenin; Apigenin 6-C-beta-glucopyranoside; Isovitexin, analytical standard; Isovitexin, >=98.0\\% (HPLC); MYXNWGACZJSMBT-VJXVFPJBSA-N; Saponaretin; Homovitexin; Saponaretin;Homovitexin; apigenin 6-C-glucoside; Apigenin-6-C-glucoside; 6-C-glucosyl-apigenin; 6-C-Glucosylapigenin; Isovitexin with HPLC; 6C-hexosyl apigenin; ISOVITEXIN [WHO-DD]; 6-glucosyl-apigenin; 6-glucosylapigenin; beta-D-isovitexin; ISOVITEXIN WITH; UNII-KTQ9R9MS0Q; Isoavroside; Saponaretin; Homovitexin; Isovitexin; KTQ9R9MS0Q; Avroside; Isovitexin



数据库引用编号

37 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

983 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 AKT1, BCL2, MTOR, NOS2, PIK3CA, PRKAA2, PTGS2
Peripheral membrane protein 3 ACHE, MTOR, PTGS2
Endoplasmic reticulum membrane 4 BCL2, HMOX1, MTOR, PTGS2
Nucleus 10 ACHE, AKT1, BCL2, FOXM1, GABPA, HMOX1, MTOR, NOS2, PPARGC1A, PRKAA2
cytosol 9 AKT1, BCL2, CD44, HMOX1, MTOR, NOS2, PIK3CA, PPARGC1A, PRKAA2
dendrite 2 MTOR, PRKAA2
phagocytic vesicle 1 MTOR
nucleoplasm 8 AKT1, FOXM1, GABPA, HMOX1, MTOR, NOS2, PPARGC1A, PRKAA2
Cell membrane 4 ACHE, AKT1, CD44, TNF
Cytoplasmic side 2 HMOX1, MTOR
lamellipodium 2 AKT1, PIK3CA
Golgi apparatus membrane 1 MTOR
Synapse 1 ACHE
cell cortex 1 AKT1
cell surface 3 ACHE, CD44, TNF
glutamatergic synapse 1 AKT1
Golgi apparatus 3 ACHE, CD44, PRKAA2
Golgi membrane 2 INS, MTOR
lysosomal membrane 2 GAA, MTOR
neuromuscular junction 1 ACHE
neuronal cell body 2 PRKAA2, TNF
postsynapse 1 AKT1
Cytoplasm, cytosol 1 NOS2
Lysosome 2 GAA, MTOR
plasma membrane 8 ACHE, AKT1, BCHE, CD44, GAA, NOS2, PIK3CA, TNF
Membrane 8 ACHE, AKT1, BCL2, CD44, GAA, HMOX1, MTOR, PRKAA2
apical plasma membrane 1 CD44
axon 1 PRKAA2
basolateral plasma membrane 1 CD44
caveola 1 PTGS2
extracellular exosome 3 CD44, GAA, SOD2
Lysosome membrane 2 GAA, MTOR
endoplasmic reticulum 3 BCL2, HMOX1, PTGS2
extracellular space 7 ACHE, BCHE, HMOX1, IL2, IL6, INS, TNF
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 4 ACHE, HMOX1, NOS2, PIK3CA
intercalated disc 1 PIK3CA
mitochondrion 2 BCL2, SOD2
protein-containing complex 3 AKT1, BCL2, PTGS2
intracellular membrane-bounded organelle 1 GAA
Microsome membrane 2 MTOR, PTGS2
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 CD44
Secreted 7 ACHE, BCHE, CD44, GAA, IL2, IL6, INS
extracellular region 8 ACHE, BCHE, CD44, GAA, IL2, IL6, INS, TNF
Mitochondrion outer membrane 2 BCL2, MTOR
Single-pass membrane protein 2 BCL2, CD44
mitochondrial outer membrane 3 BCL2, HMOX1, MTOR
Mitochondrion matrix 1 SOD2
mitochondrial matrix 1 SOD2
Extracellular side 1 ACHE
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 TNF
microtubule cytoskeleton 1 AKT1
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Cytoplasm, perinuclear region 1 NOS2
Membrane raft 1 TNF
pore complex 1 BCL2
focal adhesion 1 CD44
spindle 1 AKT1
mitochondrial nucleoid 1 SOD2
Peroxisome 1 NOS2
basement membrane 1 ACHE
peroxisomal matrix 1 NOS2
Nucleus, PML body 2 MTOR, PPARGC1A
PML body 2 MTOR, PPARGC1A
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
nuclear speck 1 PRKAA2
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
ciliary basal body 1 AKT1
chromatin 3 FOXM1, GABPA, PPARGC1A
cell projection 1 CD44
phagocytic cup 1 TNF
blood microparticle 1 BCHE
Lipid-anchor, GPI-anchor 1 ACHE
nuclear envelope 1 MTOR
Endomembrane system 1 MTOR
endosome lumen 1 INS
microvillus 1 CD44
Cell projection, microvillus 1 CD44
tertiary granule membrane 1 GAA
cytoplasmic stress granule 1 PRKAA2
side of membrane 1 ACHE
myelin sheath 1 BCL2
secretory granule lumen 1 INS
secretory granule membrane 1 CD44
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 BCHE, IL6, INS, PTGS2
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
transport vesicle 1 INS
azurophil granule membrane 1 GAA
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Single-pass type IV membrane protein 1 HMOX1
nuclear envelope lumen 1 BCHE
[Isoform 1]: Nucleus 1 PPARGC1A
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 GAA
nucleotide-activated protein kinase complex 1 PRKAA2
Cytoplasmic vesicle, phagosome 1 MTOR
lamellipodium membrane 1 CD44
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
cortical cytoskeleton 1 NOS2
macrophage migration inhibitory factor receptor complex 1 CD44
interleukin-6 receptor complex 1 IL6
autolysosome lumen 1 GAA
BAD-BCL-2 complex 1 BCL2
[Isoform H]: Cell membrane 1 ACHE
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
[Isoform B4]: Nucleus 1 PPARGC1A
[Isoform B4-8a]: Cytoplasm 1 PPARGC1A
[Isoform B5]: Nucleus 1 PPARGC1A
[Isoform 9]: Nucleus 1 PPARGC1A


文献列表

  • Hui Yu, Zhongfu Xing, Kaijie Jia, Sai Li, Yankun Xu, Pan Zhao, Xiaojing Zhu. Inquiry lipaseoring the mechanism of pancreatic lipase inhibition by isovitexin based on multispectral method and enzyme inhibition assay. Luminescence : the journal of biological and chemical luminescence. 2024 May; 39(5):e4765. doi: 10.1002/bio.4765. [PMID: 38769927]
  • Jinxiao Li, Luorui Shang, Fangyuan Zhou, Shuhan Wang, Na Liu, Minfeng Zhou, Qifeng Lin, Mengqi Zhang, Yuju Cai, Guo Chen, Shenglan Yang. Herba Patriniae and its component Isovitexin show anti-colorectal cancer effects by inducing apoptosis and cell-cycle arrest via p53 activation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Dec; 168(?):115690. doi: 10.1016/j.biopha.2023.115690. [PMID: 37939611]
  • Xiaotong Zhao, Leilei Fang, Tan Yang, Yanqing Zhang, Junbo Xie. Pharmacokinetics and Tissue Distribution of Isovitexin-2''-O-β-D-glucopyranoside (IVG) in Sprague-Dawley Rats. Current drug metabolism. 2023 Oct; ?(?):. doi: 10.2174/0113892002263771230920092659. [PMID: 37881073]
  • Lili Tian, Xinliang Wu, Hangqian Yu, Fengying Yang, Jian Sun, Tiezhong Zhou, Hong Jiang. Isovitexin Protects Mice from Methicillin-Resistant Staphylococcus aureus-Induced Pneumonia by Targeting Sortase A. Journal of microbiology and biotechnology. 2022 Oct; 32(10):1284-1291. doi: 10.4014/jmb.2206.06007. [PMID: 36224754]
  • Mingfang Tao, Rong Li, Zhuo Zhang, Ting Wu, Tingting Xu, Daniel Zogona, Yuting Huang, Siyi Pan, Xiaoyun Xu. Vitexin and Isovitexin Act through Inhibition of Insulin Receptor to Promote Longevity and Fitness in Caenorhabditis elegans. Molecular nutrition & food research. 2022 09; 66(17):e2100845. doi: 10.1002/mnfr.202100845. [PMID: 35413150]
  • Subhashis Pal, Shivani Sharma, Konica Porwal, Mohammed Riyazuddin, Chirag Kulkarni, Sourav Chattopadhyay, Sabyasachi Sanyal, Jiaur R Gayen, Naibedya Chattopadhyay. Oral Administration of Isovitexin, a Naturally Occurring Apigenin Derivative Showed Osteoanabolic Effect in Ovariectomized Mice: A Comparative Study with Teriparatide. Calcified tissue international. 2022 08; 111(2):196-210. doi: 10.1007/s00223-022-00979-9. [PMID: 35451627]
  • Yi Zhou, Zhanqiang Li, Dejun Zhang, Benyin Zhang. Screening of bioactive ingredients of Tsantan Sumtang in ameliorating H9c2 cells injury. Journal of ethnopharmacology. 2022 Mar; 285(?):114854. doi: 10.1016/j.jep.2021.114854. [PMID: 34808301]
  • Xiujiang Sun, Peng Li, Xiaoyi Qu, Wenguang Liu. Isovitexin alleviates acute gouty arthritis in rats by inhibiting inflammation via the TLR4/MyD88/NF-κB pathway. Pharmaceutical biology. 2021 Dec; 59(1):1326-1333. doi: 10.1080/13880209.2021.1979595. [PMID: 34582722]
  • Siti Zaidathul Iman Zolkiffly, Johnson Stanslas, Hafizah Abdul Hamid, Muhammad Zulfadli Mehat. Ficus deltoidea: Potential inhibitor of pro-inflammatory mediators in lipopolysaccharide-induced activation of microglial cells. Journal of ethnopharmacology. 2021 Oct; 279(?):114309. doi: 10.1016/j.jep.2021.114309. [PMID: 34119609]
  • Hua Xiang, Panpan Yang, Li Wang, Jiaxin Li, Tiedong Wang, Junze Xue, Dacheng Wang, Hongxia Ma. Isovitexin Is a Direct Inhibitor of Staphylococcus aureus Coagulase. Journal of microbiology and biotechnology. 2021 Oct; 31(10):1350-1357. doi: 10.4014/jmb.2105.05013. [PMID: 34409949]
  • Bruno César Correa Salles, Krissia Caroline Leme, Marcelo Aparecido da Silva, Cláudia Quintino da Rocha, Marcelo M P Tangerina, Wagner Vilegas, Sônia A Figueiredo, Stella Maris da Silveira Duarte, Maria Rita Rodrigues, Fernanda Borges de Araújo Paula. Protective effect of flavonoids from Passiflora edulis Sims on diabetic complications in rats. The Journal of pharmacy and pharmacology. 2021 Sep; 73(10):1361-1368. doi: 10.1093/jpp/rgab046. [PMID: 33772554]
  • Md Nurul Huda, Shuai Lu, Tanzim Jahan, Mengqi Ding, Rintu Jha, Kaixuan Zhang, Wei Zhang, Milen I Georgiev, Sang Un Park, Meiliang Zhou. Treasure from garden: Bioactive compounds of buckwheat. Food chemistry. 2021 Jan; 335(?):127653. doi: 10.1016/j.foodchem.2020.127653. [PMID: 32739818]
  • Tiejun Chen, Meizi Piao, Syed Md Ehsanur Rahman, Lehong Zhang, Yang Deng. Influence of fermentation on antioxidant and hypolipidemic properties of maifanite mineral water-cultured common buckwheat sprouts. Food chemistry. 2020 Aug; 321(?):126741. doi: 10.1016/j.foodchem.2020.126741. [PMID: 32276146]
  • Xiao-Lin Qiu, Qing-Feng Zhang. Identification and quantification of main flavonoids in the leaves of Bambusa multiplex cv. Fernleaf. Natural product research. 2020 Jul; 34(14):2076-2079. doi: 10.1080/14786419.2019.1569013. [PMID: 30721085]
  • Shuixian Liu, Xiaoxuan Zhang, Jing Wang. Isovitexin protects against cisplatin-induced kidney injury in mice through inhibiting inflammatory and oxidative responses. International immunopharmacology. 2020 Jun; 83(?):106437. doi: 10.1016/j.intimp.2020.106437. [PMID: 32222637]
  • Caifeng Meng, Ruina Liu, Wei Wang, Wei Guo, Hongyun Ma, Shuang Xie, Yimeng Liu, Chunying Wang. Metabolic profiling comparison of isovitexin in normal and kidney stone model rats by ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. Journal of separation science. 2020 Jun; 43(12):2363-2379. doi: 10.1002/jssc.201901169. [PMID: 32227654]
  • Liangyuan Chen, Xiaomin Tang, Quan Yang, Xuanxuan Cheng. Quantitative and Chemical Fingerprint Analysis of Desmodium styracifolium by High-Performance Liquid Chromatography Combined with Chemometrics. Journal of chromatographic science. 2020 Apr; 58(4):294-302. doi: 10.1093/chromsci/bmz112. [PMID: 31879757]
  • Charlyana Carvalho Bento, Marcelo Marucci P Tangerina, Ana C Zanatta, Ângela Lúcia Bagnatori Sartori, Danilo Miralha Franco, Clélia Akiko Hiruma-Lima, Wagner Vilegas, Luiz Fernando Rolim de Almeida, Miriam Sannomiya. Chemical constituents and allelopathic activity of Machaerium eriocarpum Benth. Natural product research. 2020 Mar; 34(6):884-888. doi: 10.1080/14786419.2018.1508136. [PMID: 30453777]
  • Kyoko Mashima, Mayu Hatano, Hideyuki Suzuki, Makoto Shimosaka, Goro Taguchi. Identification and Characterization of Apigenin 6-C-Glucosyltransferase Involved in Biosynthesis of Isosaponarin in Wasabi (Eutrema japonicum). Plant & cell physiology. 2019 Dec; 60(12):2733-2743. doi: 10.1093/pcp/pcz164. [PMID: 31418788]
  • Verisa Chowjarean, Tassanee Prueksasit, Keerati Joyjamras, Pithi Chanvorachote. Isovitexin Increases Stem Cell Properties and Protects Against PM2.5 in Keratinocytes. In vivo (Athens, Greece). 2019 Nov; 33(6):1833-1841. doi: 10.21873/invivo.11676. [PMID: 31662510]
  • Michael McCullagh, Cintia Alessandra Matiucci Pereira, Janete Harumi Yariwake. Use of ion mobility mass spectrometry to enhance cumulative analytical specificity and separation to profile 6-C/8-C-glycosylflavone critical isomer pairs and known-unknowns in medicinal plants. Phytochemical analysis : PCA. 2019 Jul; 30(4):424-436. doi: 10.1002/pca.2825. [PMID: 30891865]
  • Amirul Ridzuan Abu Bakar, Adiratna Mat Ripen, Amir Feisal Merican, Saharuddin Bin Mohamad. Enzymatic inhibitory activity of Ficus deltoidea leaf extract on matrix metalloproteinase-2, 8 and 9. Natural product research. 2019 Jun; 33(12):1765-1768. doi: 10.1080/14786419.2018.1434631. [PMID: 29394875]
  • Shiqi Zheng, Di Geng, Shuangyue Liu, Qingqing Wang, Siqi Liu, Rufeng Wang. A newly isolated human intestinal bacterium strain capable of deglycosylating flavone C-glycosides and its functional properties. Microbial cell factories. 2019 May; 18(1):94. doi: 10.1186/s12934-019-1144-7. [PMID: 31138294]
  • Cleide Adriane Signor Tirloni, Rhanany Alan Calloi Palozi, Maysa Isernhagen Schaedler, Lucas Pires Guarnier, Aniely Oliveira Silva, Marcia Arantes Marques, Francielly Mourão Gasparotto, Emerson Luiz Botelho Lourenço, Lauro Mera de Souza, Arquimedes Gasparotto Junior. Influence of Luehea divaricata Mart. extracts on peripheral vascular resistance and the role of nitric oxide and both Ca+2-sensitive and Kir6.1 ATP-sensitive K+ channels in the vasodilatory effects of isovitexin on isolated perfused mesenteric beds. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2019 Mar; 56(?):74-82. doi: 10.1016/j.phymed.2018.08.014. [PMID: 30668356]
  • Katherina Garcia Vanegas, Arésu Bondrup Larsen, Michael Eichenberger, David Fischer, Uffe Hasbro Mortensen, Michael Naesby. Indirect and direct routes to C-glycosylated flavones in Saccharomyces cerevisiae. Microbial cell factories. 2018 Jul; 17(1):107. doi: 10.1186/s12934-018-0952-5. [PMID: 29986709]
  • Jian-Jian Hu, Hui Wang, Chen-Wei Pan, Meng-Xiang Lin. Isovitexin alleviates liver injury induced by lipopolysaccharide/d-galactosamine by activating Nrf2 and inhibiting NF-κB activation. Microbial pathogenesis. 2018 Jun; 119(?):86-92. doi: 10.1016/j.micpath.2018.03.053. [PMID: 29604422]
  • Dominic Brauch, Andrea Porzel, Erika Schumann, Klaus Pillen, Hans-Peter Mock. Changes in isovitexin-O-glycosylation during the development of young barley plants. Phytochemistry. 2018 Apr; 148(?):11-20. doi: 10.1016/j.phytochem.2018.01.001. [PMID: 29421507]
  • Izabel Lucena Gadioli, Marcela de Sá Barreto da Cunha, Mariana Veras Oliveira de Carvalho, Ana Maria Costa, Lívia de Lacerda de Oliveira Pineli. A systematic review on phenolic compounds in Passiflora plants: Exploring biodiversity for food, nutrition, and popular medicine. Critical reviews in food science and nutrition. 2018 Mar; 58(5):785-807. doi: 10.1080/10408398.2016.1224805. [PMID: 27645583]
  • Amirul Ridzuan Abu Bakar, Thamilvaani Manaharan, Amir Feisal Merican, Saharuddin Bin Mohamad. Experimental and computational approaches to reveal the potential of Ficus deltoidea leaves extract as α-amylase inhibitor. Natural product research. 2018 Feb; 32(4):473-476. doi: 10.1080/14786419.2017.1312393. [PMID: 28391727]
  • Gavirangappa Hithamani, Dhanya Kizhakayil, Krishnapura Srinivasan. Uptake of phenolic compounds from plant foods in human intestinal Caco-2 cells. Journal of biosciences. 2017 Dec; 42(4):603-611. doi: 10.1007/s12038-017-9705-6. [PMID: 29229878]
  • Kumar Ganesan, Baojun Xu. Molecular targets of vitexin and isovitexin in cancer therapy: a critical review. Annals of the New York Academy of Sciences. 2017 08; 1401(1):102-113. doi: 10.1111/nyas.13446. [PMID: 28891090]
  • Yinnan Sun, Kui Yang, Qin Cao, Jinde Sun, Yu Xia, Yinhang Wang, Wei Li, Chunhui Ma, Shouxin Liu. Homogenate-assisted Vacuum-powered Bubble Extraction of Moso Bamboo Flavonoids for On-line Scavenging Free Radical Capacity Analysis. Molecules (Basel, Switzerland). 2017 Jul; 22(7):. doi: 10.3390/molecules22071156. [PMID: 28696360]
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