Betulin (BioDeep_00000000550)

 

Secondary id: BioDeep_00000403518

human metabolite PANOMIX_OTCML-2023 Endogenous Volatile Flavor Compounds natural product


代谢物信息卡片


(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol

化学式: C30H50O2 (442.38106)
中文名称: 桦木脑, 白桦醇, 桦脑, 白桦脂醇
谱图信息: 最多检出来源 Viridiplantae(plant) 0.41%

分子结构信息

SMILES: C1[C@@]2(C)[C@@]([H])(CC[C@]3(C)[C@]2([H])CC[C@@]2([C@@]4([C@](CC[C@@]32C)(CO)CC[C@H]4C(C)=C)[H])[H])C(C)(C)[C@@H](O)C1
InChI: InChI=1S/C30H50O2/c1-19(2)20-10-15-30(18-31)17-16-28(6)21(25(20)30)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h20-25,31-32H,1,8-18H2,2-7H3/t20-,21+,22-,23+,24-,25+,27-,28+,29+,30+/m0/s1

描述信息

Betulin is found in black elderberry. Betulin is a constituent of Corylus avellana (filbert) and Vicia faba. Betulin (lup-20(29)-ene-3 ,28-diol) is an abundant naturally occurring triterpene. It is commonly isolated from the bark of birch trees and forms up to 30\\\\\% of the dry weight of the extractive. The purpose of the compound in the bark is not known. It can be converted to betulinic acid (the alcohol group replaced by a carboxylic acid group), which is biologically more active than betulin itself. Chemically, betulin is a triterpenoid of lupane structure. It has a pentacyclic ring structure, and hydroxyl groups in positions C3 and C28
Betulin is a pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-hydroxymethyl substituents. It has a role as a metabolite, an antiviral agent, an analgesic, an anti-inflammatory agent and an antineoplastic agent. It is a pentacyclic triterpenoid and a diol. It derives from a hydride of a lupane.
Betulin is a natural product found in Diospyros morrisiana, Euonymus carnosus, and other organisms with data available.
A pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-hydroxymethyl substituents.
Constituent of Corylus avellana (filbert) and Vicia faba
Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC50 of 14.5 μM in K562 cell line.
Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC50 of 14.5 μM in K562 cell line.
Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC50 of 14.5 μM in K562 cell line.

同义名列表

62 个代谢物同义名

(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol; (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(hydroxymethyl)-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol; (3aS,5bR,9S,11aR)-3a-(hydroxymethyl)-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol;Betulin; (1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-5-(hydroxymethyl)-1,2,14,18,18-pentamethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0^{2,10}.0^{5,9}.0^{14,19}]henicosan-17-ol; (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3 a-(hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-ol; (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(Hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-ol; lup-20(29)-ene-3,28-diol, 3,28-diacetate, (3 beta)-; Lup-20(29)-ene-3,28-diol, (3.beta.)-; Lup-20(29)-ene-3,28-diol, (3beta )-; (3.beta.)-Lup-20(29)-ene-3,28-diol; lup-20(29)-en-3 alpha, 28,30-triol; Lup-20(29)-ene-3,28-diol, (3beta)-; 3beta,28-Dihydroxylup-20(29)-ene; (3beta)-lup-20(29)-ene-3,28-diol; Lup-20(30)-ene-3.beta.,28-diol; Lup-20(29)-ene-3.beta.,28-diol; Lup-20(29)-ene-3beta ,28-diol; 3Β,28-dihydroxylup-20(29)-ene; (3Β)-lup-20(29)-ene-3,28-diol; lup-20(29)-ene-3 beta,28-diol; Lup-20(30)-ene-3beta ,28-diol; lup-20(29)-ene-3alpha,28-diol; Lup-20(30)-ene-3beta,28-diol; Betulin, analytical standard; Lup-20(29)-ene-3beta,28-diol; FVWJYYTZTCVBKE-ROUWMTJPSA-N; Lup-20(30)-ene-3β,28-diol; Lup-20(29)-ene-3β,28-diol; Lup-20(29)-ene-3 ,28-diol; Betulinol (obsol pound(c); Lup-20(29)-ene-3b,28-diol; 3,28-di-O-acetylbetulin; 3,28-diacetoxy-betulin; 3,28-Dihydroxy-lupeol; (+)-betulin diacetate; betulinol biacetate; betulinol diacetate; Betulinol (obsol.); Prestwick3_000990; betulinic alcohol; betulin diacetate; Betulin, >=98\\%; UNII-6W70HN7X7O; BETULIN [INCI]; BPBio1_001165; MEGxp0_001726; ORISTRACT BTL; ACon1_000091; BETULIN [MI]; (+)-betulin; Betulin, 23; 6W70HN7X7O; CP BETULIN; betulinol; AI3-62999; betuline; Betulin; Betulol; Trochol; Lup-20(29)-ene-3,28-diol; Betulo; Betulin



数据库引用编号

27 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

88 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(86)

  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: H+ + NADPH + O2 + betulin ⟶ H2O + NADP+ + betulinic aldehyde
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + betulin ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulinic aldehyde
  • betulinate biosynthesis: H+ + NADPH + O2 + betulin ⟶ H2O + NADP+ + betulinic aldehyde
  • betulinate biosynthesis: H+ + NADPH + O2 + lupeol ⟶ H2O + NADP+ + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: H+ + NADPH + O2 + betulin ⟶ H2O + NADP+ + betulinic aldehyde
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + betulin ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulinic aldehyde
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: H+ + NADPH + O2 + betulin ⟶ H2O + NADP+ + betulinic aldehyde
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + lupeol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + betulin
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + betulinic aldehyde ⟶ H+ + H2O + an oxidized [NADPH-hemoprotein reductase] + betulinate
  • betulinate biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + betulinic aldehyde ⟶ H+ + H2O + an oxidized [NADPH-hemoprotein reductase] + betulinate

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PathBank(0)

PharmGKB(0)

913 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Prativa Biswasroy, Deepak Pradhan, Dilip Kumar Pradhan, Goutam Ghosh, Goutam Rath. Development of Betulin-Loaded Nanostructured Lipid Carriers for the Management of Imiquimod-Induced Psoriasis. AAPS PharmSciTech. 2024 Mar; 25(3):57. doi: 10.1208/s12249-024-02774-1. [PMID: 38472545]
  • Feyisayo O Adepoju, Ksenia V Sokolova, Irina F Gette, Irina G Danilova, Mikhail V Tsurkan, Alicia C Mondragon, Elena G Kovaleva, Jose Manuel Miranda. Protective Effect of Betulin on Streptozotocin-Nicotinamide-Induced Diabetes in Female Rats. International journal of molecular sciences. 2024 Feb; 25(4):. doi: 10.3390/ijms25042166. [PMID: 38396842]
  • Yiding Deng, Ruili Wang, Zhiyuan Ma, Weiwei Zuo, Meifang Zhu. Synthesis and Fabrication of Betulin-Derived Polysulfide and Polysulfoxide Electrospun Fibers for Fruit Preservation. Journal of agricultural and food chemistry. 2023 Dec; 71(48):18857-18864. doi: 10.1021/acs.jafc.3c07117. [PMID: 37994873]
  • Mengdi Lv, Yue Zheng, Jian Wu, Zhengqi Shen, Binglian Guo, Guojing Hu, Yuanlei Huang, Jingyue Zhao, Yong Qian, Zhi Su, Chao Wu, Xuling Xue, Hong-Ke Liu, Zong-Wan Mao. Evoking Ferroptosis by Synergistic Enhancement of a Cyclopentadienyl Iridium-Betulin Immune Agonist. Angewandte Chemie (International ed. in English). 2023 Oct; ?(?):e202312897. doi: 10.1002/anie.202312897. [PMID: 37830171]
  • Umesh Chandra Dash, Sandeep Kumar Swain, Atala Bihari Jena, Jagnehswar Dandapat, Atish Kumar Sahoo. The ameliorative effect of Piper trioicum in attenuating cognitive deficit in scopolamine induced neurotoxicity in experimental rats. Journal of ethnopharmacology. 2023 Jul; ?(?):116911. doi: 10.1016/j.jep.2023.116911. [PMID: 37451488]
  • Kai-Yuan Chen, Wei-Lin Hsu, Shih-Wei Hsu, Chao-Hsuan Chen, Kun-Ting Hong, Chia-Wen Tsai, Wen-Shin Chang, Chao-Chun Chen, Jen-Sheng Pei, Hsu-Tung Lee, DA-Tian Bau. Involvement of Mitochondrial Damage and Oxidative Stress in Apoptosis Induced by Betulin Plus Arsenic Trioxide in Neuroblastoma Cells. Anticancer research. 2023 Jun; 43(6):2467-2476. doi: 10.21873/anticanres.16414. [PMID: 37247918]
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