Lignoceric acid (BioDeep_00000400368)

Main id: BioDeep_00000002668

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


Tetracosanoic acid

化学式: C24H48O2 (368.36541079999995)
中文名称: 木蜡酸, 二十四烷酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCCCCCCCCCCCCCCCCCC(=O)O
InChI: InChI=1S/C24H48O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h2-23H2,1H3,(H,25,26)

描述信息

A C24 straight-chain saturated fatty acid.
Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].
Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].

同义名列表

3 个代谢物同义名

Tetracosanoic acid; Lignoceric acid; Tetracosanoic acid



数据库引用编号

30 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

406 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yudai Yamashita, Takayuki Narita, Yushi Oishi. Non-Equilibrium Phase-Separated State of(Palmitic Acid/Lignoceric Acid) Mixed Monolayer. Journal of oleo science. 2020 Jun; 69(6):569-572. doi: 10.5650/jos.ess20038. [PMID: 32404553]
  • Danni Li, Jeffrey R Misialek, Ma Jing, Michael Y Tsai, John H Eckfeldt, Lyn M Steffen, David Knopman, Lisa Wruck, Rebecca Gottesman, Tom H Mosley, A Richey Sharrett, Alvaro Alonso. Plasma phospholipid very-long-chain SFAs in midlife and 20-year cognitive change in the Atherosclerosis Risk in Communities (ARIC): a cohort study. The American journal of clinical nutrition. 2020 06; 111(6):1252-1258. doi: 10.1093/ajcn/nqaa048. [PMID: 32320012]
  • Anna Petroni, Rita Paroni, Anna Maria Aloisi, Milena Blasevich, Nabil Haman, Dimitrios Fessas. Thermogenic flux induced by lignoceric acid in peroxisomes isolated from HepG2 cells and from X-adrenoleukodystrophy and control fibroblasts. Journal of cellular physiology. 2019 08; 234(10):18344-18348. doi: 10.1002/jcp.28467. [PMID: 30932193]
  • Rozenn N Lemaitre, Paul N Jensen, Andrew Hoofnagle, Barbara McKnight, Amanda M Fretts, Irena B King, David S Siscovick, Bruce M Psaty, Susan R Heckbert, Dariush Mozaffarian, Nona Sotoodehnia. Plasma Ceramides and Sphingomyelins in Relation to Heart Failure Risk. Circulation. Heart failure. 2019 07; 12(7):e005708. doi: 10.1161/circheartfailure.118.005708. [PMID: 31296099]
  • Atsushi Henmi, Minori Shoji, Masato Nomura, Toshio Inoue. Fatty Acid Composition and Applications of Eriobotrya japonica Seed Oil. Journal of oleo science. 2019 Jul; 68(7):599-606. doi: 10.5650/jos.ess18178. [PMID: 31178459]
  • Anna Sofia Tascini, Massimo G Noro, John M Seddon, Rongjun Chen, Fernando Bresme. Mechanisms of lipid extraction from skin lipid bilayers by sebum triglycerides. Physical chemistry chemical physics : PCCP. 2019 Jan; 21(3):1471-1477. doi: 10.1039/c8cp05706k. [PMID: 30607404]
  • Maren Podewitz, Yin Wang, Paraskevi Gkeka, Susanne von Grafenstein, Klaus R Liedl, Zoe Cournia. Phase Diagram of a Stratum Corneum Lipid Mixture. The journal of physical chemistry. B. 2018 11; 122(46):10505-10521. doi: 10.1021/acs.jpcb.8b07200. [PMID: 30351111]
  • Rozenn N Lemaitre, Barbara McKnight, Nona Sotoodehnia, Amanda M Fretts, Waqas T Qureshi, Xiaoling Song, Irena B King, Colleen M Sitlani, David S Siscovick, Bruce M Psaty, Dariush Mozaffarian. Circulating Very Long-Chain Saturated Fatty Acids and Heart Failure: The Cardiovascular Health Study. Journal of the American Heart Association. 2018 11; 7(21):e010019. doi: 10.1161/jaha.118.010019. [PMID: 30608197]
  • Maryem Bezine, Sonia Maatoug, Rym Ben Khalifa, Meryam Debbabi, Amira Zarrouk, Yuqin Wang, William J Griffiths, Thomas Nury, Mohammad Samadi, Anne Vejux, Jérôme de Sèze, Thibault Moreau, Riadh Kharrat, Mohamed El Ayeb, Gérard Lizard. Modulation of Kv3.1b potassium channel level and intracellular potassium concentration in 158N murine oligodendrocytes and BV-2 murine microglial cells treated with 7-ketocholesterol, 24S-hydroxycholesterol or tetracosanoic acid (C24:0). Biochimie. 2018 Oct; 153(?):56-69. doi: 10.1016/j.biochi.2018.02.008. [PMID: 29462682]
  • Maryem Bezine, Meryam Debbabi, Thomas Nury, Rym Ben-Khalifa, Mohammad Samadi, Mustapha Cherkaoui-Malki, Anne Vejux, Quentin Raas, Jérôme de Sèze, Thibault Moreau, Mohamed El-Ayeb, Gérard Lizard. Evidence of K+ homeostasis disruption in cellular dysfunction triggered by 7-ketocholesterol, 24S-hydroxycholesterol, and tetracosanoic acid (C24:0) in 158N murine oligodendrocytes. Chemistry and physics of lipids. 2017 10; 207(Pt B):135-150. doi: 10.1016/j.chemphyslip.2017.03.006. [PMID: 28322741]
  • Petra Pullmannová, Ludmila Pavlíková, Andrej Kováčik, Michaela Sochorová, Barbora Školová, Petr Slepička, Jaroslav Maixner, Jarmila Zbytovská, Kateřina Vávrová. Permeability and microstructure of model stratum corneum lipid membranes containing ceramides with long (C16) and very long (C24) acyl chains. Biophysical chemistry. 2017 05; 224(?):20-31. doi: 10.1016/j.bpc.2017.03.004. [PMID: 28363088]
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  • Enamul H Mojumdar, Gert S Gooris, David J Barlow, M Jayne Lawrence, Bruno Deme, Joke A Bouwstra. Skin lipids: localization of ceramide and fatty acid in the unit cell of the long periodicity phase. Biophysical journal. 2015 Jun; 108(11):2670-9. doi: 10.1016/j.bpj.2015.04.030. [PMID: 26039168]
  • Seshadri Shivashankar, Manoharan Sumathi. Do seed VLCFAs trigger spongy tissue formation in Alphonso mango by inducing germination?. Journal of biosciences. 2015 Jun; 40(2):375-87. doi: 10.1007/s12038-015-9515-7. [PMID: 25963264]
  • Sören Stahlberg, Barbora Školová, Perunthiruthy K Madhu, Alexander Vogel, Kateřina Vávrová, Daniel Huster. Probing the role of the ceramide acyl chain length and sphingosine unsaturation in model skin barrier lipid mixtures by (2)H solid-state NMR spectroscopy. Langmuir : the ACS journal of surfaces and colloids. 2015 May; 31(17):4906-15. doi: 10.1021/acs.langmuir.5b00751. [PMID: 25870928]
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  • Bruna Renata Casadei, Patrícia De Oliveira Carvalho, Karin A Riske, Raquel De Melo Barbosa, Eneida De Paula, Cleyton Crepaldi Domingues. Brij detergents reveal new aspects of membrane microdomain in erythrocytes. Molecular membrane biology. 2014 Sep; 31(6):195-205. doi: 10.3109/09687688.2014.949319. [PMID: 25222860]
  • Masashi Oguri, Gert S Gooris, Kotatsu Bito, Joke A Bouwstra. The effect of the chain length distribution of free fatty acids on the mixing properties of stratum corneum model membranes. Biochimica et biophysica acta. 2014 Jul; 1838(7):1851-61. doi: 10.1016/j.bbamem.2014.02.009. [PMID: 24565794]
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  • Yuya Yamazaki, Kazuya Kondo, Ryouta Maeba, Megumi Nishimukai, Toru Nezu, Hiroshi Hara. Proportion of nervonic acid in serum lipids is associated with serum plasmalogen levels and metabolic syndrome. Journal of oleo science. 2014; 63(5):527-37. doi: 10.5650/jos.ess13226. [PMID: 24770479]
  • Dong Chang, Shengzhong Rong, Yannan Zhang, Qian Sha, Meihua Liang, Xuefei Zhang, Miaojing Li, Hongzhi Pan. Serum free fatty acids level in senile cataract. Journal of the American College of Nutrition. 2014; 33(5):406-11. doi: 10.1080/07315724.2013.875420. [PMID: 25079310]
  • E H Mojumdar, D Groen, G S Gooris, D J Barlow, M J Lawrence, B Deme, J A Bouwstra. Localization of cholesterol and fatty acid in a model lipid membrane: a neutron diffraction approach. Biophysical journal. 2013 Aug; 105(4):911-8. doi: 10.1016/j.bpj.2013.07.003. [PMID: 23972843]
  • Juyoung Kim, Jin Hee Jung, Saet Buyl Lee, Young Sam Go, Hae Jin Kim, Rebecca Cahoon, Jennifer E Markham, Edgar B Cahoon, Mi Chung Suh. Arabidopsis 3-ketoacyl-coenzyme a synthase9 is involved in the synthesis of tetracosanoic acids as precursors of cuticular waxes, suberins, sphingolipids, and phospholipids. Plant physiology. 2013 06; 162(2):567-80. doi: 10.1104/pp.112.210450. [PMID: 23585652]
  • Shiyou Lü, Huayan Zhao, David L Des Marais, Eugene P Parsons, Xiaoxue Wen, Xiaojing Xu, Dhinoth K Bangarusamy, Guangchao Wang, Owen Rowland, Thomas Juenger, Ray A Bressan, Matthew A Jenks. Arabidopsis ECERIFERUM9 involvement in cuticle formation and maintenance of plant water status. Plant physiology. 2012 Jul; 159(3):930-44. doi: 10.1104/pp.112.198697. [PMID: 22635115]
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  • Xiaohong Qiao, Xiaotian Xie, Shayi Jiang, Wei Shi, Jinqing Tang, Nina Zhou. Experimental bone marrow failure in mice ameliorated by OCH via tippling the balance of released cytokines from Th1 to Th2. Immunopharmacology and immunotoxicology. 2012 Jun; 34(3):491-8. doi: 10.3109/08923973.2011.633525. [PMID: 22124468]
  • Stefan Tresch, Monika Heilmann, Nicole Christiansen, Ralf Looser, Klaus Grossmann. Inhibition of saturated very-long-chain fatty acid biosynthesis by mefluidide and perfluidone, selective inhibitors of 3-ketoacyl-CoA synthases. Phytochemistry. 2012 Apr; 76(?):162-71. doi: 10.1016/j.phytochem.2011.12.023. [PMID: 22284369]
  • Qun Sun, Ye Lu, Shuang-Qing Wu, Shi Yao, Jian Zhang. [Study on the chemical constituents from Gnaphalium hypoleucum]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2012 Apr; 35(4):566-8. doi: ". [PMID: 23019902]
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