Isovitexin (BioDeep_00000400118)

Main id: BioDeep_00000000204

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


5,7-dihydroxy-2-(4-hydroxyphenyl)-6-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one

化学式: C21H20O10 (432.105642)
中文名称: 异牡荆素, 异牡荆黄素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1(O)=CC2OC(C3C=CC(O)=CC=3)=CC(=O)C=2C(O)=C1[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1
InChI: InChI=1S/C38H40O19/c1-51-22-9-15(10-23(52-2)29(22)43)3-8-26(42)53-14-25-31(45)34(48)36(50)38(57-25)56-21-12-20-27(18(41)11-19(54-20)16-4-6-17(40)7-5-16)32(46)28(21)37-35(49)33(47)30(44)24(13-39)55-37/h3-12,24-25,30-31,33-40,43-50H,13-14H2,1-2H3/b8-3+

描述信息

Isovitexin is a C-glycosyl compound that consists of apigenin substituted by a 1,5-anhydro-D-glucitol moiety at position 6. It has a role as an EC 3.2.1.20 (alpha-glucosidase) inhibitor and a metabolite. It is a C-glycosyl compound and a trihydroxyflavone. It is functionally related to an apigenin. It is a conjugate acid of an isovitexin-7-olate.
Isovitexin is a natural product found in Carex fraseriana, Rauhiella, and other organisms with data available.
See also: Fenugreek seed (part of); Acai (part of); Crataegus monogyna flowering top (part of).
A C-glycosyl compound that consists of apigenin substituted by a 1,5-anhydro-D-glucitol moiety at position 6.
Isovitexin is a member of the class of compounds known as flavonoid c-glycosides. Flavonoid c-glycosides are compounds containing a carbohydrate moiety which is C-glycosidically linked to the 2-phenylchromen-4-one flavonoid backbone. Isovitexin is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Isovitexin can be found in a number of food items such as common salsify, winged bean, flaxseed, and common buckwheat, which makes isovitexin a potential biomarker for the consumption of these food products. Isovitexin (or homovitexin, saponaretin) is a flavone. the apigenin-6-C-glucoside. It can be found in the passion flower, Cannabis, and the açaí palm .
Constituent of Cucumis sativus (cucumber). Isovitexin 2-(6-p-coumaroylglucoside) 4-glucoside is found in cucumber and fruits.
Constituent of young green barley leaves (Hordeum vulgare variety nudum). Isovitexin 7-(6-sinapoylglucoside) is found in barley and cereals and cereal products.
Isovitexin is a flavonoid isolated from passion flower, Cannabis and, and the palm, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB.
Isovitexin is a flavonoid isolated from passion flower, Cannabis and, and the palm, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB.

同义名列表

59 个代谢物同义名

5,7-dihydroxy-2-(4-hydroxyphenyl)-6-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]chromen-4-one; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one; (1S)-1,5-anhydro-1-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl]-D-glucitol; 4H-1-Benzopyran-4-one, 6-beta-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)- (VAN); (1S)-1,5-anhydro-1-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl)-D-glucitol; 4H-1-Benzopyran-4-one, 6-.beta.-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 4H-1-Benzopyran-4-one, 6-beta-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 6-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one,6-尾-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-; Ethyl6-amino-5-cyano-2-methyl-4-phenyl-4H-pyran-3-carboxylate; ISOVITEXIN (CONSTITUENT OF HAWTHORN LEAF WITH FLOWER); Isovitexin, primary pharmaceutical reference standard; Flavone, 6-.beta.-D-glucopyranosyl-4,5,7-trihydroxy-; Flavone, 6-beta-D-glucopyranosyl-4,5,7-trihydroxy-; 6-beta-D-Glucopyranosyl-4,5,7-trihydroxyflavone; 6-(beta-D-glucopyranosyl)-2-hydroxynaringenin; 6-C-glucosyl-4,5,7-trihydroxyflavone; 6-C-.BETA.-D-GLUCOPYRANOSYLAPIGENIN; 6-C-beta-D-Glucopyranosylapigenin; Apigenin 6-C-beta-glucopyranoside; Isovitexin, analytical standard; Isovitexin, >=98.0\\% (HPLC); MYXNWGACZJSMBT-VJXVFPJBSA-N; Saponaretin; Homovitexin; Saponaretin;Homovitexin; apigenin 6-C-glucoside; Apigenin-6-C-glucoside; 6-C-glucosyl-apigenin; 6-C-Glucosylapigenin; Isovitexin with HPLC; 6C-hexosyl apigenin; ISOVITEXIN [WHO-DD]; 6-glucosyl-apigenin; 6-glucosylapigenin; beta-D-isovitexin; ISOVITEXIN WITH; UNII-KTQ9R9MS0Q; Isoavroside; Saponaretin; Homovitexin; Isovitexin; KTQ9R9MS0Q; Avroside; Isovitexin 2-(6-p-coumaroylglucoside) 4-glucoside; Isovitexin 7-(6-sinapoylglucoside); 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]-4-chromenone; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]chromone; 4H-1-Benzopyran-4-one, 6-beta-D-glucopyranosyl-5,7- dihydroxy-2-(4-hydroxyphenyl)-; NCGC00163578-01; AIDS-339232; CHEBI:18330; 29702-25-8; 38953-85-4; AIDS339232; 61838-34-4; 61383-34-4; C01714; Isovitexin



数据库引用编号

31 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

954 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hui Yu, Zhongfu Xing, Kaijie Jia, Sai Li, Yankun Xu, Pan Zhao, Xiaojing Zhu. Inquiry lipaseoring the mechanism of pancreatic lipase inhibition by isovitexin based on multispectral method and enzyme inhibition assay. Luminescence : the journal of biological and chemical luminescence. 2024 May; 39(5):e4765. doi: 10.1002/bio.4765. [PMID: 38769927]
  • Jinxiao Li, Luorui Shang, Fangyuan Zhou, Shuhan Wang, Na Liu, Minfeng Zhou, Qifeng Lin, Mengqi Zhang, Yuju Cai, Guo Chen, Shenglan Yang. Herba Patriniae and its component Isovitexin show anti-colorectal cancer effects by inducing apoptosis and cell-cycle arrest via p53 activation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Dec; 168(?):115690. doi: 10.1016/j.biopha.2023.115690. [PMID: 37939611]
  • Xiaotong Zhao, Leilei Fang, Tan Yang, Yanqing Zhang, Junbo Xie. Pharmacokinetics and Tissue Distribution of Isovitexin-2''-O-β-D-glucopyranoside (IVG) in Sprague-Dawley Rats. Current drug metabolism. 2023 Oct; ?(?):. doi: 10.2174/0113892002263771230920092659. [PMID: 37881073]
  • Lili Tian, Xinliang Wu, Hangqian Yu, Fengying Yang, Jian Sun, Tiezhong Zhou, Hong Jiang. Isovitexin Protects Mice from Methicillin-Resistant Staphylococcus aureus-Induced Pneumonia by Targeting Sortase A. Journal of microbiology and biotechnology. 2022 Oct; 32(10):1284-1291. doi: 10.4014/jmb.2206.06007. [PMID: 36224754]
  • Mingfang Tao, Rong Li, Zhuo Zhang, Ting Wu, Tingting Xu, Daniel Zogona, Yuting Huang, Siyi Pan, Xiaoyun Xu. Vitexin and Isovitexin Act through Inhibition of Insulin Receptor to Promote Longevity and Fitness in Caenorhabditis elegans. Molecular nutrition & food research. 2022 09; 66(17):e2100845. doi: 10.1002/mnfr.202100845. [PMID: 35413150]
  • Subhashis Pal, Shivani Sharma, Konica Porwal, Mohammed Riyazuddin, Chirag Kulkarni, Sourav Chattopadhyay, Sabyasachi Sanyal, Jiaur R Gayen, Naibedya Chattopadhyay. Oral Administration of Isovitexin, a Naturally Occurring Apigenin Derivative Showed Osteoanabolic Effect in Ovariectomized Mice: A Comparative Study with Teriparatide. Calcified tissue international. 2022 08; 111(2):196-210. doi: 10.1007/s00223-022-00979-9. [PMID: 35451627]
  • Yi Zhou, Zhanqiang Li, Dejun Zhang, Benyin Zhang. Screening of bioactive ingredients of Tsantan Sumtang in ameliorating H9c2 cells injury. Journal of ethnopharmacology. 2022 Mar; 285(?):114854. doi: 10.1016/j.jep.2021.114854. [PMID: 34808301]
  • Xiujiang Sun, Peng Li, Xiaoyi Qu, Wenguang Liu. Isovitexin alleviates acute gouty arthritis in rats by inhibiting inflammation via the TLR4/MyD88/NF-κB pathway. Pharmaceutical biology. 2021 Dec; 59(1):1326-1333. doi: 10.1080/13880209.2021.1979595. [PMID: 34582722]
  • Siti Zaidathul Iman Zolkiffly, Johnson Stanslas, Hafizah Abdul Hamid, Muhammad Zulfadli Mehat. Ficus deltoidea: Potential inhibitor of pro-inflammatory mediators in lipopolysaccharide-induced activation of microglial cells. Journal of ethnopharmacology. 2021 Oct; 279(?):114309. doi: 10.1016/j.jep.2021.114309. [PMID: 34119609]
  • Hua Xiang, Panpan Yang, Li Wang, Jiaxin Li, Tiedong Wang, Junze Xue, Dacheng Wang, Hongxia Ma. Isovitexin Is a Direct Inhibitor of Staphylococcus aureus Coagulase. Journal of microbiology and biotechnology. 2021 Oct; 31(10):1350-1357. doi: 10.4014/jmb.2105.05013. [PMID: 34409949]
  • Bruno César Correa Salles, Krissia Caroline Leme, Marcelo Aparecido da Silva, Cláudia Quintino da Rocha, Marcelo M P Tangerina, Wagner Vilegas, Sônia A Figueiredo, Stella Maris da Silveira Duarte, Maria Rita Rodrigues, Fernanda Borges de Araújo Paula. Protective effect of flavonoids from Passiflora edulis Sims on diabetic complications in rats. The Journal of pharmacy and pharmacology. 2021 Sep; 73(10):1361-1368. doi: 10.1093/jpp/rgab046. [PMID: 33772554]
  • Md Nurul Huda, Shuai Lu, Tanzim Jahan, Mengqi Ding, Rintu Jha, Kaixuan Zhang, Wei Zhang, Milen I Georgiev, Sang Un Park, Meiliang Zhou. Treasure from garden: Bioactive compounds of buckwheat. Food chemistry. 2021 Jan; 335(?):127653. doi: 10.1016/j.foodchem.2020.127653. [PMID: 32739818]
  • Tiejun Chen, Meizi Piao, Syed Md Ehsanur Rahman, Lehong Zhang, Yang Deng. Influence of fermentation on antioxidant and hypolipidemic properties of maifanite mineral water-cultured common buckwheat sprouts. Food chemistry. 2020 Aug; 321(?):126741. doi: 10.1016/j.foodchem.2020.126741. [PMID: 32276146]
  • Xiao-Lin Qiu, Qing-Feng Zhang. Identification and quantification of main flavonoids in the leaves of Bambusa multiplex cv. Fernleaf. Natural product research. 2020 Jul; 34(14):2076-2079. doi: 10.1080/14786419.2019.1569013. [PMID: 30721085]
  • Shuixian Liu, Xiaoxuan Zhang, Jing Wang. Isovitexin protects against cisplatin-induced kidney injury in mice through inhibiting inflammatory and oxidative responses. International immunopharmacology. 2020 Jun; 83(?):106437. doi: 10.1016/j.intimp.2020.106437. [PMID: 32222637]
  • Caifeng Meng, Ruina Liu, Wei Wang, Wei Guo, Hongyun Ma, Shuang Xie, Yimeng Liu, Chunying Wang. Metabolic profiling comparison of isovitexin in normal and kidney stone model rats by ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. Journal of separation science. 2020 Jun; 43(12):2363-2379. doi: 10.1002/jssc.201901169. [PMID: 32227654]
  • Liangyuan Chen, Xiaomin Tang, Quan Yang, Xuanxuan Cheng. Quantitative and Chemical Fingerprint Analysis of Desmodium styracifolium by High-Performance Liquid Chromatography Combined with Chemometrics. Journal of chromatographic science. 2020 Apr; 58(4):294-302. doi: 10.1093/chromsci/bmz112. [PMID: 31879757]
  • Charlyana Carvalho Bento, Marcelo Marucci P Tangerina, Ana C Zanatta, Ângela Lúcia Bagnatori Sartori, Danilo Miralha Franco, Clélia Akiko Hiruma-Lima, Wagner Vilegas, Luiz Fernando Rolim de Almeida, Miriam Sannomiya. Chemical constituents and allelopathic activity of Machaerium eriocarpum Benth. Natural product research. 2020 Mar; 34(6):884-888. doi: 10.1080/14786419.2018.1508136. [PMID: 30453777]
  • Kyoko Mashima, Mayu Hatano, Hideyuki Suzuki, Makoto Shimosaka, Goro Taguchi. Identification and Characterization of Apigenin 6-C-Glucosyltransferase Involved in Biosynthesis of Isosaponarin in Wasabi (Eutrema japonicum). Plant & cell physiology. 2019 Dec; 60(12):2733-2743. doi: 10.1093/pcp/pcz164. [PMID: 31418788]
  • Verisa Chowjarean, Tassanee Prueksasit, Keerati Joyjamras, Pithi Chanvorachote. Isovitexin Increases Stem Cell Properties and Protects Against PM2.5 in Keratinocytes. In vivo (Athens, Greece). 2019 Nov; 33(6):1833-1841. doi: 10.21873/invivo.11676. [PMID: 31662510]
  • Michael McCullagh, Cintia Alessandra Matiucci Pereira, Janete Harumi Yariwake. Use of ion mobility mass spectrometry to enhance cumulative analytical specificity and separation to profile 6-C/8-C-glycosylflavone critical isomer pairs and known-unknowns in medicinal plants. Phytochemical analysis : PCA. 2019 Jul; 30(4):424-436. doi: 10.1002/pca.2825. [PMID: 30891865]
  • Amirul Ridzuan Abu Bakar, Adiratna Mat Ripen, Amir Feisal Merican, Saharuddin Bin Mohamad. Enzymatic inhibitory activity of Ficus deltoidea leaf extract on matrix metalloproteinase-2, 8 and 9. Natural product research. 2019 Jun; 33(12):1765-1768. doi: 10.1080/14786419.2018.1434631. [PMID: 29394875]
  • Shiqi Zheng, Di Geng, Shuangyue Liu, Qingqing Wang, Siqi Liu, Rufeng Wang. A newly isolated human intestinal bacterium strain capable of deglycosylating flavone C-glycosides and its functional properties. Microbial cell factories. 2019 May; 18(1):94. doi: 10.1186/s12934-019-1144-7. [PMID: 31138294]
  • Cleide Adriane Signor Tirloni, Rhanany Alan Calloi Palozi, Maysa Isernhagen Schaedler, Lucas Pires Guarnier, Aniely Oliveira Silva, Marcia Arantes Marques, Francielly Mourão Gasparotto, Emerson Luiz Botelho Lourenço, Lauro Mera de Souza, Arquimedes Gasparotto Junior. Influence of Luehea divaricata Mart. extracts on peripheral vascular resistance and the role of nitric oxide and both Ca+2-sensitive and Kir6.1 ATP-sensitive K+ channels in the vasodilatory effects of isovitexin on isolated perfused mesenteric beds. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2019 Mar; 56(?):74-82. doi: 10.1016/j.phymed.2018.08.014. [PMID: 30668356]
  • Katherina Garcia Vanegas, Arésu Bondrup Larsen, Michael Eichenberger, David Fischer, Uffe Hasbro Mortensen, Michael Naesby. Indirect and direct routes to C-glycosylated flavones in Saccharomyces cerevisiae. Microbial cell factories. 2018 Jul; 17(1):107. doi: 10.1186/s12934-018-0952-5. [PMID: 29986709]
  • Jian-Jian Hu, Hui Wang, Chen-Wei Pan, Meng-Xiang Lin. Isovitexin alleviates liver injury induced by lipopolysaccharide/d-galactosamine by activating Nrf2 and inhibiting NF-κB activation. Microbial pathogenesis. 2018 Jun; 119(?):86-92. doi: 10.1016/j.micpath.2018.03.053. [PMID: 29604422]
  • Dominic Brauch, Andrea Porzel, Erika Schumann, Klaus Pillen, Hans-Peter Mock. Changes in isovitexin-O-glycosylation during the development of young barley plants. Phytochemistry. 2018 Apr; 148(?):11-20. doi: 10.1016/j.phytochem.2018.01.001. [PMID: 29421507]
  • Izabel Lucena Gadioli, Marcela de Sá Barreto da Cunha, Mariana Veras Oliveira de Carvalho, Ana Maria Costa, Lívia de Lacerda de Oliveira Pineli. A systematic review on phenolic compounds in Passiflora plants: Exploring biodiversity for food, nutrition, and popular medicine. Critical reviews in food science and nutrition. 2018 Mar; 58(5):785-807. doi: 10.1080/10408398.2016.1224805. [PMID: 27645583]
  • Amirul Ridzuan Abu Bakar, Thamilvaani Manaharan, Amir Feisal Merican, Saharuddin Bin Mohamad. Experimental and computational approaches to reveal the potential of Ficus deltoidea leaves extract as α-amylase inhibitor. Natural product research. 2018 Feb; 32(4):473-476. doi: 10.1080/14786419.2017.1312393. [PMID: 28391727]
  • Gavirangappa Hithamani, Dhanya Kizhakayil, Krishnapura Srinivasan. Uptake of phenolic compounds from plant foods in human intestinal Caco-2 cells. Journal of biosciences. 2017 Dec; 42(4):603-611. doi: 10.1007/s12038-017-9705-6. [PMID: 29229878]
  • Kumar Ganesan, Baojun Xu. Molecular targets of vitexin and isovitexin in cancer therapy: a critical review. Annals of the New York Academy of Sciences. 2017 08; 1401(1):102-113. doi: 10.1111/nyas.13446. [PMID: 28891090]
  • Yinnan Sun, Kui Yang, Qin Cao, Jinde Sun, Yu Xia, Yinhang Wang, Wei Li, Chunhui Ma, Shouxin Liu. Homogenate-assisted Vacuum-powered Bubble Extraction of Moso Bamboo Flavonoids for On-line Scavenging Free Radical Capacity Analysis. Molecules (Basel, Switzerland). 2017 Jul; 22(7):. doi: 10.3390/molecules22071156. [PMID: 28696360]
  • Vinod Bhatt, Sushila Sharma, Neeraj Kumar, Upendra Sharma, Bikram Singh. Simultaneous quantification and identification of flavonoids, lignans, coumarin and amides in leaves of Zanthoxylum armatum using UPLC-DAD-ESI-QTOF-MS/MS. Journal of pharmaceutical and biomedical analysis. 2017 Jan; 132(?):46-55. doi: 10.1016/j.jpba.2016.09.035. [PMID: 27693952]
  • Miao He, Jia-Wei Min, Wei-Lin Kong, Xiao-Hua He, Jun-Xu Li, Bi-Wen Peng. A review on the pharmacological effects of vitexin and isovitexin. Fitoterapia. 2016 Dec; 115(?):74-85. doi: 10.1016/j.fitote.2016.09.011. [PMID: 27693342]
  • Kristýna Večeřová, Zbyněk Večeřa, Bohumil Dočekal, Michal Oravec, Antonio Pompeiano, Jan Tříska, Otmar Urban. Changes of primary and secondary metabolites in barley plants exposed to CdO nanoparticles. Environmental pollution (Barking, Essex : 1987). 2016 Nov; 218(?):207-218. doi: 10.1016/j.envpol.2016.05.013. [PMID: 27503055]
  • Petra Terpinc, Blaž Cigić, Tomaž Polak, Janez Hribar, Tomaž Požrl. LC-MS analysis of phenolic compounds and antioxidant activity of buckwheat at different stages of malting. Food chemistry. 2016 Nov; 210(?):9-17. doi: 10.1016/j.foodchem.2016.04.030. [PMID: 27211614]
  • R Kesavan, S Chandel, S Upadhyay, R Bendre, R Ganugula, U R Potunuru, H Giri, G Sahu, P Uday Kumar, G Bhanuprakash Reddy, G Joksic, A K Bera, Madhulika Dixit. Gentiana lutea exerts anti-atherosclerotic effects by preventing endothelial inflammation and smooth muscle cell migration. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2016 Apr; 26(4):293-301. doi: 10.1016/j.numecd.2015.12.016. [PMID: 26868432]
  • Yue-ming Zuo, Yuan-li Xu, Zhong-li Zhang, Dian-hang Liu. [Study on Chemical Components of Tripterospermum chinense ( Ⅱ)]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2016 Mar; 39(3):552-4. doi: ". [PMID: 30088884]
  • Kely Cristina Dos Santos, Tatiane Vieira Borges, Gislaine Olescowicz, Fabiana Kalyne Ludka, Cid Aimbiré de Moraes Santos, Simone Molz. Passiflora actinia hydroalcoholic extract and its major constituent, isovitexin, are neuroprotective against glutamate-induced cell damage in mice hippocampal slices. The Journal of pharmacy and pharmacology. 2016 Feb; 68(2):282-91. doi: 10.1111/jphp.12512. [PMID: 26800497]
  • Camila Carla Guimarães, Denise Dias Oliveira, Mayara Valdevite, Ana Lúcia Fachin Saltoratto, Sarazete Izidia Vaz Pereira, Suzelei de Castro França, Ana Maria Soares Pereira, Paulo Sérgio Pereira. The glycosylated flavonoids vitexin, isovitexin, and quercetrin isolated from Serjania erecta Radlk (Sapindaceae) leaves protect PC12 cells against amyloid-β25-35 peptide-induced toxicity. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2015 Dec; 86(?):88-94. doi: 10.1016/j.fct.2015.09.002. [PMID: 26385725]
  • Sebastian Granica, Holger Kluge, Gert Horn, Adam Matkowski, Anna K Kiss. The phytochemical investigation of Agrimonia eupatoria L. and Agrimonia procera Wallr. as valid sources of Agrimoniae herba--The pharmacopoeial plant material. Journal of pharmaceutical and biomedical analysis. 2015 Oct; 114(?):272-9. doi: 10.1016/j.jpba.2015.05.027. [PMID: 26092224]
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  • Yaxin Li, Yanqing Zhang, Tan Yang, Hui Li, Jiang Guo, Qiqing Zhao, Junbo Xie. Pharmacokinetics and tissue distribution study of Isovitexin in rats by HPLC-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2015 Jun; 991(?):13-20. doi: 10.1016/j.jchromb.2015.04.003. [PMID: 25902051]
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