Secoisolariciresinol (BioDeep_00000398758)

Secondary id: BioDeep_00000179078, BioDeep_00000860995, BioDeep_00001890990

PANOMIX_OTCML-2023

代谢物信息卡片

(-)-Secoisolariciresinol

化学式: C20H26O6 (362.17292960000003)
中文名称: 异豆香脂素, 开环异落叶松树脂酚
谱图信息: 最多检出来源 Homo sapiens(blood) 0.27%

分子结构信息

SMILES: COC1=C(C=CC(=C1)CC(CO)C(CC2=CC(=C(C=C2)O)OC)CO)O
InChI: InChI=1S/C20H26O6/c1-25-19-9-13(3-5-17(19)23)7-15(11-21)16(12-22)8-14-4-6-18(24)20(10-14)26-2/h3-6,9-10,15-16,21-24H,7-8,11-12H2,1-2H3

描述信息

Annotation level-1
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D004967 - Estrogens
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.816
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.813
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.806
Secoisolariciresinol is a lignan, a type of phenylpropanoids.
Secoisolariciresinol is a lignan, a type of phenylpropanoids.

同义名列表

2 个代谢物同义名

Secoisolariciresinol; (-)-Secoisolariciresinol

数据库引用编号

52 个数据库交叉引用编号

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

257 个相关的物种来源信息

50506 Sargentodoxa cuneata: 10.3987/COM-03-9777
3311 Ginkgo biloba: 10.3389/FPLS.2019.00983
1650721 Rubia yunnanensis:
22663 Punica granatum:
105808 Crossosoma bigelovii: 10.1021/NP8006342
2753873 Daphne feddei: 10.1021/NP8004166
4640 Musa:
3661 Cucurbita maxima:
3846 Glycine:
3746 Fragaria:
29760 Vitis vinifera:
3760 Prunus persica:
2034236 Cucumis melo var. dudaim: 10.1207/S15327914NC5402_5
3654 Citrullus lanatus:
42345 Phoenix dactylifera:
4039 Daucus carota:
3716 Brassica oleracea var. capitata:
4146 Olea europaea:
3755 Prunus dulcis: 10.1207/S15327914NC5402_5
21019 Castanea:
13450 Corylus: 10.1207/S15327914NC5402_5
13442 Coffea: 10.1207/S15327914NC5402_5
3713 Brassica oleracea var. viridis:
3562 Spinacia oleracea:
3656 Cucumis melo:
4236 Lactuca sativa:
51240 Juglans regia: 10.1207/S15327914NC5402_5
32201 Carya illinoinensis: 10.1207/S15327914NC5402_5
78511 Ribes nigrum:
4577 Zea mays:
4682 Allium sativum:
55513 Pistacia vera: 10.1207/S15327914NC5402_5
3818 Arachis hypogaea:
36596 Prunus armeniaca:
4442 Camellia sinensis: 10.1207/S15327914NC5402_5
3712 Brassica oleracea:
3750 Malus domestica:
283210 Malus pumila:
4565 Triticum aestivum:
4072 Capsicum annuum:
4615 Ananas comosus:
3715 Brassica oleracea var. botrytis:
4113 Solanum tuberosum:
171929 Anacardium occidentale: 10.1079/BJN20051371
3758 Prunus domestica:
4006 Linum usitatissimum:
13427 Cichorium intybus:
3663 Cucurbita pepo:
4232 Helianthus annuus: 10.1079/BJN20051371
36774 Brassica oleracea var. italica:
323851 Prunus persica var. nucipersica:
3468 Papaver: 10.1079/BJN20051371
3625 Actinidia chinensis:
3659 Cucumis sativus:
23211 Pyrus communis:
85571 Citrus reticulata:
558547 Citrus deliciosa:
4182 Sesamum indicum: 10.1079/BJN20051371
3885 Phaseolus vulgaris:
137893 Saussurea medusa:
180763 Vaccinium myrtillus: 10.1016/J.FOODCHEM.2012.03.133
57936 Rubus chamaemorus: 10.1016/J.FOODCHEM.2012.03.133
180772 Vaccinium vitis-idaea: 10.1016/J.FOODCHEM.2012.03.133
4513 Hordeum vulgare: 10.1021/JF051488W
4498 Avena sativa: 10.1021/JF051488W
3726 Raphanus sativus:
109996 Raphanus raphanistrum:
4111 Solanum melongena:
240228 Raphanus sativus var. sativus:
4686 Asparagus officinalis:
3617 Fagopyrum esculentum: 10.1021/JF051488W
4550 Secale cereale: 10.1021/JF051488W
136894 Catunaregam spinosa: 10.1002/CHIN.200844208
1090621 Stereospermum colais: 10.1021/NP058036Y
1401051 Stereospermum tetragonum: 10.1021/NP058036Y
1351 Enterococcus faecalis: 10.1248/CPB.51.508
25629 Taxus baccata:
35974 Santalum album:
91146 Sedum sarmentosum:
211974 Berberis koreana: 10.1016/J.BMCL.2011.02.104
56992 Araucaria angustifolia: 10.1016/S0031-9422(00)89347-4
285591 Tinospora crispa: 10.1055/S-2006-957466
188928 Larix gmelinii var. olgensis: 10.1021/NP058022S
308264 Brassica fruticulosa: 10.1021/JF034644C
746496 Phyllanthus angkorensis: 10.1021/NP050001A
1108177 Campylotropis hirtella: 10.1021/JF800476R
459149 Homalolepis cuneata: 10.1016/0031-9422(92)80374-N
3708 Brassica napus:
3906 Vicia faba: 10.1016/J.FOODCHEM.2009.03.002
175228 Ribes rubrum: 10.1016/J.FOODCHEM.2009.03.002
65948 Nasturtium officinale: 10.1016/J.FOODCHEM.2009.03.002
1216010 Brassica oleracea var. sabauda: 10.1016/J.FOODCHEM.2009.03.002
78168 Passiflora edulis: 10.1016/J.FOODCHEM.2009.03.002
35925 Diospyros kaki: 10.1016/J.FOODCHEM.2009.03.002
3711 Brassica rapa: 10.1016/J.FOODCHEM.2009.03.002
3888 Pisum sativum: 10.1016/J.FOODCHEM.2009.03.002
35875 Allium fistulosum: 10.1016/J.FOODCHEM.2009.03.002
4045 Apium graveolens: 10.1016/J.FOODCHEM.2009.03.002
3649 Carica papaya: 10.1016/J.FOODCHEM.2009.03.002
3494 Ficus carica: 10.1016/J.FOODCHEM.2009.03.002
135518 Ribes uva-crispa: 10.1016/J.FOODCHEM.2009.03.002
157791 Vigna radiata: 10.1016/J.FOODCHEM.2009.03.002
3435 Persea americana: 10.1016/J.FOODCHEM.2009.03.002
3620 Rheum: 10.1016/J.FOODCHEM.2009.03.002
36609 Cydonia: 10.1016/J.FOODCHEM.2009.03.002
29780 Mangifera indica: 10.1016/J.FOODCHEM.2009.03.002
4041 Pastinaca sativa: 10.1016/J.FOODCHEM.2009.03.002
151069 Litchi chinensis: 10.1016/J.FOODCHEM.2009.03.002
4043 Petroselinum crispum: 10.1016/J.FOODCHEM.2009.03.002
4120 Ipomoea batatas: 10.1016/J.FOODCHEM.2009.03.002
3827 Cicer arietinum: 10.1016/J.FOODCHEM.2009.03.002
39352 Origanum vulgare: 10.1079/BJN2002794
4650 Zingiber: 10.1079/BJN2002794
39350 Ocimum basilicum: 10.1079/BJN2002794
65558 Capparis spinosa: 10.1079/BJN2002794
161934 Beta vulgaris: 10.1079/BJN2002794
180536 Eruca vesicaria: 10.1079/BJN2002794
3704 Armoracia rusticana: 10.1079/BJN2002794
3641 Theobroma cacao: 10.1079/BJN2002794
48119 Glehnia littoralis: 10.1248/CPB.50.73
3501 Urtica dioica: 10.1055/S-2006-957756
103972 Fitzroya cupressoides: 10.3891/ACTA.CHEM.SCAND.23-2021
147273 Taxus wallichiana: 10.1016/J.BMC.2003.09.010
4217 Arctium lappa:
413484 Vitex rotundifolia: 10.1021/NP000307B
1835378 Brosimum acutifolium: 10.1055/S-2002-32906
3359 Tsuga heterophylla: 10.1016/S0031-9422(00)00126-6
191219 Linum album:
50506 Sargentodoxa cuneata: 10.3987/COM-03-9777
3311 Ginkgo biloba: 10.3389/FPLS.2019.00983
1650721 Rubia yunnanensis:
22663 Punica granatum:
105808 Crossosoma bigelovii: 10.1021/NP8006342
2753873 Daphne feddei: 10.1021/NP8004166
4640 Musa:
3661 Cucurbita maxima:
3846 Glycine:
3746 Fragaria:
29760 Vitis vinifera:
3760 Prunus persica:
2034236 Cucumis melo var. dudaim: 10.1207/S15327914NC5402_5
3654 Citrullus lanatus:
42345 Phoenix dactylifera:
4039 Daucus carota:
3716 Brassica oleracea var. capitata:
4146 Olea europaea:
3755 Prunus dulcis: 10.1207/S15327914NC5402_5
21019 Castanea:
13450 Corylus: 10.1207/S15327914NC5402_5
13442 Coffea: 10.1207/S15327914NC5402_5
3713 Brassica oleracea var. viridis:
3562 Spinacia oleracea:
3656 Cucumis melo:
4236 Lactuca sativa:
51240 Juglans regia: 10.1207/S15327914NC5402_5
32201 Carya illinoinensis: 10.1207/S15327914NC5402_5
78511 Ribes nigrum:
4577 Zea mays:
4682 Allium sativum:
55513 Pistacia vera: 10.1207/S15327914NC5402_5
3818 Arachis hypogaea:
36596 Prunus armeniaca:
4442 Camellia sinensis: 10.1207/S15327914NC5402_5
3712 Brassica oleracea:
3750 Malus domestica:
283210 Malus pumila:
4565 Triticum aestivum:
4072 Capsicum annuum:
4615 Ananas comosus:
3715 Brassica oleracea var. botrytis:
4113 Solanum tuberosum:
171929 Anacardium occidentale: 10.1079/BJN20051371
3758 Prunus domestica:
4006 Linum usitatissimum:
13427 Cichorium intybus:
3663 Cucurbita pepo:
4232 Helianthus annuus: 10.1079/BJN20051371
36774 Brassica oleracea var. italica:
323851 Prunus persica var. nucipersica:
3468 Papaver: 10.1079/BJN20051371
3625 Actinidia chinensis:
3659 Cucumis sativus:
23211 Pyrus communis:
85571 Citrus reticulata:
558547 Citrus deliciosa:
4182 Sesamum indicum: 10.1079/BJN20051371
3885 Phaseolus vulgaris:
137893 Saussurea medusa:
180763 Vaccinium myrtillus: 10.1016/J.FOODCHEM.2012.03.133
57936 Rubus chamaemorus: 10.1016/J.FOODCHEM.2012.03.133
180772 Vaccinium vitis-idaea: 10.1016/J.FOODCHEM.2012.03.133
4513 Hordeum vulgare: 10.1021/JF051488W
4498 Avena sativa: 10.1021/JF051488W
3726 Raphanus sativus:
109996 Raphanus raphanistrum:
4111 Solanum melongena:
240228 Raphanus sativus var. sativus:
4686 Asparagus officinalis:
3617 Fagopyrum esculentum: 10.1021/JF051488W
4550 Secale cereale: 10.1021/JF051488W
136894 Catunaregam spinosa: 10.1002/CHIN.200844208
1090621 Stereospermum colais: 10.1021/NP058036Y
1401051 Stereospermum tetragonum: 10.1021/NP058036Y
1351 Enterococcus faecalis: 10.1248/CPB.51.508
25629 Taxus baccata:
35974 Santalum album:
91146 Sedum sarmentosum:
211974 Berberis koreana: 10.1016/J.BMCL.2011.02.104
56992 Araucaria angustifolia: 10.1016/S0031-9422(00)89347-4
285591 Tinospora crispa: 10.1055/S-2006-957466
188928 Larix gmelinii var. olgensis: 10.1021/NP058022S
308264 Brassica fruticulosa: 10.1021/JF034644C
746496 Phyllanthus angkorensis: 10.1021/NP050001A
1108177 Campylotropis hirtella: 10.1021/JF800476R
459149 Homalolepis cuneata: 10.1016/0031-9422(92)80374-N
3708 Brassica napus:
3906 Vicia faba: 10.1016/J.FOODCHEM.2009.03.002
175228 Ribes rubrum: 10.1016/J.FOODCHEM.2009.03.002
65948 Nasturtium officinale: 10.1016/J.FOODCHEM.2009.03.002
1216010 Brassica oleracea var. sabauda: 10.1016/J.FOODCHEM.2009.03.002
78168 Passiflora edulis: 10.1016/J.FOODCHEM.2009.03.002
35925 Diospyros kaki: 10.1016/J.FOODCHEM.2009.03.002
3711 Brassica rapa: 10.1016/J.FOODCHEM.2009.03.002
3888 Pisum sativum: 10.1016/J.FOODCHEM.2009.03.002
35875 Allium fistulosum: 10.1016/J.FOODCHEM.2009.03.002
4045 Apium graveolens: 10.1016/J.FOODCHEM.2009.03.002
3649 Carica papaya: 10.1016/J.FOODCHEM.2009.03.002
3494 Ficus carica: 10.1016/J.FOODCHEM.2009.03.002
135518 Ribes uva-crispa: 10.1016/J.FOODCHEM.2009.03.002
157791 Vigna radiata: 10.1016/J.FOODCHEM.2009.03.002
3435 Persea americana: 10.1016/J.FOODCHEM.2009.03.002
3620 Rheum: 10.1016/J.FOODCHEM.2009.03.002
36609 Cydonia: 10.1016/J.FOODCHEM.2009.03.002
29780 Mangifera indica: 10.1016/J.FOODCHEM.2009.03.002
4041 Pastinaca sativa: 10.1016/J.FOODCHEM.2009.03.002
151069 Litchi chinensis: 10.1016/J.FOODCHEM.2009.03.002
4043 Petroselinum crispum: 10.1016/J.FOODCHEM.2009.03.002
4120 Ipomoea batatas: 10.1016/J.FOODCHEM.2009.03.002
3827 Cicer arietinum: 10.1016/J.FOODCHEM.2009.03.002
39352 Origanum vulgare: 10.1079/BJN2002794
4650 Zingiber: 10.1079/BJN2002794
39350 Ocimum basilicum: 10.1079/BJN2002794
65558 Capparis spinosa: 10.1079/BJN2002794
161934 Beta vulgaris: 10.1079/BJN2002794
180536 Eruca vesicaria: 10.1079/BJN2002794
3704 Armoracia rusticana: 10.1079/BJN2002794
3641 Theobroma cacao: 10.1079/BJN2002794
48119 Glehnia littoralis: 10.1248/CPB.50.73
3501 Urtica dioica: 10.1055/S-2006-957756
103972 Fitzroya cupressoides: 10.3891/ACTA.CHEM.SCAND.23-2021
147273 Taxus wallichiana: 10.1016/J.BMC.2003.09.010
4217 Arctium lappa:
413484 Vitex rotundifolia: 10.1021/NP000307B
1835378 Brosimum acutifolium: 10.1055/S-2002-32906
3359 Tsuga heterophylla: 10.1016/S0031-9422(00)00126-6
191219 Linum album:
33090 Plants: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Jing Chen, Hui Chen, Chengcheng Feng, Qiong Chen, Xiang Fang, Yong Wang, Ning Zhang. Anti-inflammatory effect of lignans from flaxseed after fermentation by lactiplantibacillus plantarum SCB0151 in vitro. World journal of microbiology & biotechnology. 2024 Mar; 40(4):134. doi: 10.1007/s11274-024-03945-9. [PMID: 38480613]
Zhiqiang Li, Haonan Zhang, Wanting Li, Min Yao, Huimin Yu, Mingzhen He, Yulin Feng, Zhifeng Li. Potential antioxidative components from Syringa oblata Lindl stems revealed by affinity ultrafiltration with multiple drug targets. Bioorganic chemistry. 2023 May; 138(?):106604. doi: 10.1016/j.bioorg.2023.106604. [PMID: 37178648]
U K Hussain Zaki, C Fryganas, L Trijsburg, E J M Feskens, E Capuano. Influence of different processing method on lignan content of selected Malaysian plant-based foods. Food chemistry. 2023 Mar; 404(Pt A):134607. doi: 10.1016/j.foodchem.2022.134607. [PMID: 36272303]
Xiumei Han, Leonid Akhov, Paula Ashe, Courteney Lewis, Leah Deibert, L Irina Zaharia, Lily Forseille, Daoquan Xiang, Raju Datla, Matthew Nosworthy, Carol Henry, Jitao Zou, Bianyun Yu, Nii Patterson. Comprehensive compositional assessment of bioactive compounds in diverse pea accessions. Food research international (Ottawa, Ont.). 2023 03; 165(?):112455. doi: 10.1016/j.foodres.2022.112455. [PMID: 36869474]
Joanda P R E Silva, Laiane C O Pereira, Lucas S Abreu, Francisca S V Lins, Thalisson A de Souza, Renan F do Espírito-Santo, Renata P C Barros, Cristiane F Villarreal, José I M de Melo, Marcus T Scotti, Vicente C de O Costa, Lucas H Martorano, Fernando M Dos Santos, Raimundo Braz Filho, Marcelo S da Silva, Josean F Tavares. Targeted Isolation of Anti-inflammatory Lignans from Justicia aequilabris by Molecular Networking Approach. Journal of natural products. 2022 09; 85(9):2184-2191. doi: 10.1021/acs.jnatprod.2c00478. [PMID: 35998343]
Xixian Feng, Fanjia Peng, Zujun Yin, Junjuan Wang, Yuexin Zhang, Hong Zhang, Yapeng Fan, Nan Xu, Hui Huang, Kesong Ni, Xiaoyu Liu, Yuqian Lei, Tiantian Jiang, Jing Wang, Cun Rui, Chao Chen, Shuai Wang, Xiugui Chen, Xuke Lu, Delong Wang, Lixue Guo, Lanjie Zhao, Yujun Li, Yongbo Wang, Wuwei Ye. Secondary metabolite pathway of SDG (secoisolariciresinol) was observed to trigger ROS scavenging system in response to Ca2+ stress in cotton. Genomics. 2022 07; 114(4):110398. doi: 10.1016/j.ygeno.2022.110398. [PMID: 35675878]
Sameh S Elhady, Elsayed A Ibrahim, Marwa S Goda, Mohamed S Nafie, Hanan Samir, Reem M Diri, Abdulrahman M Alahdal, Ama Kyeraa Thomford, Alaa El Gindy, Ghada M Hadad, Jihan M Badr, Reda F A Abdelhameed. GC-MS/MS Quantification of EGFR Inhibitors, β-Sitosterol, Betulinic Acid, (+) Eriodictyol, (+) Epipinoresinol, and Secoisolariciresinol, in Crude Extract and Ethyl Acetate Fraction of Thonningia sanguinea. Molecules (Basel, Switzerland). 2022 Jun; 27(13):. doi: 10.3390/molecules27134109. [PMID: 35807354]
Leyla Polat Kose, İlhami Gulcin. Evaluation of the Antioxidant and Antiradical Properties of Some Phyto and Mammalian Lignans. Molecules (Basel, Switzerland). 2021 Nov; 26(23):. doi: 10.3390/molecules26237099. [PMID: 34885681]
Bushra Asad, Taimoor Khan, Faiza Zareen Gul, Muhammad Asad Ullah, Samantha Drouet, Sara Mikac, Laurine Garros, Manon Ferrier, Shankhamala Bose, Thibaut Munsch, Duangjai Tungmunnithum, Arnaud Lanoue, Nathalie Giglioli-Guivarc'h, Christophe Hano, Bilal Haider Abbasi. Scarlet Flax Linum grandiflorum (L.) In Vitro Cultures as a New Source of Antioxidant and Anti-Inflammatory Lignans. Molecules (Basel, Switzerland). 2021 Jul; 26(15):. doi: 10.3390/molecules26154511. [PMID: 34361665]
Xiaolei Yang, Yajia Guo, Timothy J Tse, Sarah K Purdy, Rana Mustafa, Jianheng Shen, Jane Alcorn, Martin J T Reaney. Oral Pharmacokinetics of Enriched Secoisolariciresinol Diglucoside and Its Polymer in Rats. Journal of natural products. 2021 06; 84(6):1816-1822. doi: 10.1021/acs.jnatprod.1c00335. [PMID: 34043363]
Ying Xiao, Kai Shao, Jingwen Zhou, Lian Wang, Xueqi Ma, Di Wu, Yingbo Yang, Junfeng Chen, Jingxian Feng, Shi Qiu, Zongyou Lv, Lei Zhang, Peng Zhang, Wansheng Chen. Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases. Nature communications. 2021 05; 12(1):2828. doi: 10.1038/s41467-021-23095-y. [PMID: 33990581]
Karolina Dobrowolska, Bożena Regulska-Ilow. The legitimacy of using dietary supplement diglycoside secoisolariciresinol (SDG) from flaxseed in cancer. Roczniki Panstwowego Zakladu Higieny. 2021; 72(1):9-20. doi: 10.32394/rpzh.2021.0144. [PMID: 33882661]
Cong-Cong Zhuang, Xu Feng, Hai-Yan Xu, Li Zhang, Ling Liu, Gong Zhang, Zhong Zheng, Chao-Mei Ma. Technical note: Quantification of lignans in the urine, milk, and plasma of flaxseed cake-fed dairy sheep. Journal of dairy science. 2021 Jan; 104(1):391-396. doi: 10.3168/jds.2020-18470. [PMID: 33189295]
Bouchentouf Salim, Ghalem Said, Nadia Kambouche, Soumaya Kress. Identification of Phenolic Compounds from Nettle as New Candidate Inhibitors of Main Enzymes Responsible on Type-II Diabetes. Current drug discovery technologies. 2020; 17(2):197-202. doi: 10.2174/1570163815666180829094831. [PMID: 30156162]
Chen Cheng, Xiao Yu, David Julian McClements, Qingde Huang, Hu Tang, Kun Yu, Xia Xiang, Peng Chen, Xintian Wang, Qianchun Deng. Effect of flaxseed polyphenols on physical stability and oxidative stability of flaxseed oil-in-water nanoemulsions. Food chemistry. 2019 Dec; 301(?):125207. doi: 10.1016/j.foodchem.2019.125207. [PMID: 31377621]
Lucija Markulin, Cyrielle Corbin, Sullivan Renouard, Samantha Drouet, Laurent Gutierrez, Ivan Mateljak, Daniel Auguin, Christophe Hano, Elisabeth Fuss, Eric Lainé. Pinoresinol-lariciresinol reductases, key to the lignan synthesis in plants. Planta. 2019 Jun; 249(6):1695-1714. doi: 10.1007/s00425-019-03137-y. [PMID: 30895445]
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