Naringenin (BioDeep_00000000072)

 

Secondary id: BioDeep_00000017700, BioDeep_00000270572, BioDeep_00000606443

natural product human metabolite PANOMIX_OTCML-2023 blood metabolite PANOMIX-Anthocyanidin BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2S)-

化学式: C15H12O5 (272.0684702)
中文名称: 柚皮素
谱图信息: 最多检出来源 Homo sapiens(feces) 0.01%

Reviewed

Last reviewed on 2024-07-09.

Cite this Page

Naringenin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/naringenin (retrieved 2024-11-21) (BioDeep RN: BioDeep_00000000072). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1(O)C=C2O[C@H](C3=CC=C(O)C=C3)CC(=O)C2=C(O)C=1
InChI: InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2

描述信息

Naringenin is a flavorless, colorless flavanone, a type of flavonoid. It is the predominant flavanone in grapefruit, and is found in a variety of fruits and herbs. Naringenin has the skeleton structure of a flavanone with three hydroxy groups at the 4, 5, and 7 carbons. It may be found both in the aglycol form, naringenin, or in its glycosidic form, naringin, which has the addition of the disaccharide neohesperidose attached via a glycosidic linkage at carbon 7. Naringenin (not to be confused with naringin) is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promoter, immunity system modulater. This substance has also been shown to repair DNA. Scientists exposed cells to 80 micomoles of naringenin per liter, for 24 hours, and found that the amount of hydroxyl damage to the DNA was reduced by 24 percent in that very short period of time. Unfortunately, this bioflavonoid is difficult to absorb on oral ingestion. Only 15\\\\\\\% of ingested naringenin will get absorbed, in the human gastrointestinal tract, in the best case scenario. A full glass of orange juice will supply about enough naringenin to achieve a concentration of about 0.5 micromoles per liter. Naringenin is a biomarker for the consumption of citrus fruits.
(S)-naringenin is the (S)-enantiomer of naringenin. It has a role as an expectorant and a plant metabolite. It is a naringenin and a (2S)-flavan-4-one. It is a conjugate acid of a (S)-naringenin(1-). It is an enantiomer of a (R)-naringenin.
Naringenin is a natural product found in Elaeodendron croceum, Garcinia multiflora, and other organisms with data available.
See also: Naringin (related).
Most widely distributed flavanone. Citrus fruits (grapefruit, oranges and pummelos) are especially good sources. Glycosides also widely distributed

The (S)-enantiomer of naringenin.

[Raw Data] CB070_Naringenin_pos_20eV_CB000030.txt
[Raw Data] CB070_Naringenin_pos_10eV_CB000030.txt
[Raw Data] CB070_Naringenin_pos_40eV_CB000030.txt
[Raw Data] CB070_Naringenin_pos_30eV_CB000030.txt
[Raw Data] CB070_Naringenin_pos_50eV_CB000030.txt

[Raw Data] CB070_Naringenin_neg_10eV_000021.txt
[Raw Data] CB070_Naringenin_neg_30eV_000021.txt
[Raw Data] CB070_Naringenin_neg_50eV_000021.txt
[Raw Data] CB070_Naringenin_neg_20eV_000021.txt
[Raw Data] CB070_Naringenin_neg_40eV_000021.txt

(±)-Naringenin. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=67604-48-2 (retrieved 2024-07-09) (CAS RN: 67604-48-2). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
(±)-Naringenin is a naturally-occurring flavonoid. (±)-Naringenin displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes[1].
(±)-Naringenin is a naturally-occurring flavonoid. (±)-Naringenin displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes[1].
Naringenin is the predominant flavanone in Citrus reticulata Blanco; displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity.
Naringenin is the predominant flavanone in Citrus reticulata Blanco; displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity.

同义名列表

72 个代谢物同义名

4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2S)-; 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (S)-; 4H-1-Benzopyran-4-one,2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2S)-; (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; (2S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; (S)-2,3-dihydo-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 2,3-Dihydro-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one; 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one; (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one; (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one; (-)-(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one; (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one; 5,7-dihydroxy-2-(4-hydroxyphenyl)-4h-chroman-4-one; (S)-5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one; Flavanone, 4,5,7-trihydroxy- (8CI); (2S)-4,5,7-trihydroxyflavan-4-one; (2S)-4’,5,7-Trihydroxyflavanone; (2S)-4,5,7-trihydroxyflavanone; Flavanone, 4,5,7-trihydroxy-; 4,5,7-trihydroxyflavan-4-one; (2S)-5,7,4-trihydroxyflavone; Phytochemistry 8: 127 (1969); FTVWIRXFELQLPI-ZDUSSCGKSA-N; 4,5, 7-Trihydroxyflavanone; 5,7,4’-Trihydroxyflavanone; 4,5,7-trihydroxyflavanone; 5,7,4-Trihydroxyflavanone; 4,5,7-Trihydroxyflavanon; naringenin-7-sulfate; 4,5,7-triOH-Flavone; (-)-(2S)-Naringenin; S-Dihydrogenistein; NARINGENIN [INCI]; Spectrum3_000567; NARINGENIN, (-)-; Spectrum5_001423; (R,S)-Naringenin; Spectrum2_000325; Spectrum4_000124; (2S)-naringenin; NARINGENIN [MI]; (-)-Naringenin; (S)-Naringenin; DivK1c_000118; KBio2_003295; KBio2_000727; pelargidanon; KBio2_005863; KBio3_001454; KBio1_000118; Naringenine; IDI1_000118; Naringenin; salipurpol; naringetol; NARIGENIN; Salipurol; AI3-23355; C15H12O5; Asahina; Nari; 2uxu; YSO1; 4eh3; 4deu; 4 5 7-trihydroxyflavanone; (±)-Naringenin; Naringenin



数据库引用编号

77 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(5)

PlantCyc(0)

代谢反应

896 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(15)

WikiPathways(0)

Plant Reactome(237)

INOH(0)

PlantCyc(641)

COVID-19 Disease Map(0)

PathBank(3)

PharmGKB(0)

541 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mohsen Akbari, Salar Moardi, Homeyra Piri, Roonak Amiri, Farzaneh Aliaqabozorg, Elham Sadat Afraz. The identification of active compounds and therapeutic properties of fermented and non-fermented red sorghum for the treatment of Alzheimer's dementia. Experimental gerontology. 2024 Jul; 192(?):112459. doi: 10.1016/j.exger.2024.112459. [PMID: 38740315]
  • Liyao Liu, Lifei Lv, Wenjie Dai, Jinju Nie. The effect of naringenin-phospholipid complex on thermal oxidative stability of soybean oil under heating condition. Food chemistry. 2024 Jun; 444(?):138631. doi: 10.1016/j.foodchem.2024.138631. [PMID: 38325079]
  • Ying-Ting Yu, Hong-Ru Lin, Xin-Yan Chen, Meng-Lu Sun, Cong-Min Wei, Meng-Fan Xue, Yi-Huai Gao, Wen-Bo Tang, Chun-Yuan Zheng, Shan Li, Hong-Bing Wang. Dendrobium officinale phenolic extract maintains proteostasis by regulating autophagy in a Caenorhabditis elegans model of Alzheimer's disease. Fitoterapia. 2024 Jun; 175(?):105924. doi: 10.1016/j.fitote.2024.105924. [PMID: 38537886]
  • Olga Wesołowska, Anna Duda-Madej, Maria Błaszczyk, Kamila Środa-Pomianek, Joanna Kozłowska, Mirosław Anioł. Interaction of selected alkoxy naringenin oximes with model and bacterial membranes. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 May; 174(?):116581. doi: 10.1016/j.biopha.2024.116581. [PMID: 38636394]
  • Meng Ding, Yuan Zhu, Xiaoting Xu, Hui He, Tianyu Jiang, Xiaochuan Mo, Zhuting Wang, Wenfeng Yu, Hailong Ou. Naringenin Inhibits Acid Sphingomyelinase-Mediated Membrane Raft Clustering to Reduce NADPH Oxidase Activation and Vascular Inflammation. Journal of agricultural and food chemistry. 2024 Apr; 72(13):7130-7139. doi: 10.1021/acs.jafc.3c07874. [PMID: 38516841]
  • Jiashuo Zhang, Weiyang Fan, Hao Wu, Yue Yao, Linlin Jin, Ruiqi Chen, Ziyan Xu, Weiwei Su, Yonggang Wang, Peibo Li. Naringenin attenuated airway cilia structural and functional injury induced by cigarette smoke extract via IL-17 and cAMP pathways. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Apr; 126(?):155053. doi: 10.1016/j.phymed.2023.155053. [PMID: 38359483]
  • Wenbo Li, Xin Yan, Wenli Xia, Linguo Zhao, Jianjun Pei. Enzymatic properties and immobilization of a thermostable prenyltransferase from Aspergillus fumigatiaffinis for the production of prenylated naringenin. Bioorganic chemistry. 2024 Apr; 145(?):107183. doi: 10.1016/j.bioorg.2024.107183. [PMID: 38340474]
  • Luana Heimfarth, Katielen Silvana Dos Santos, Brenda Souza Monteiro, Anne Karoline de Souza Oliveira, Henrique Douglas M Coutinho, Irwin R A Menezes, Marcio Roberto Viana Dos Santos, Adriano Antunes de Souza Araújo, Laurent Picot, Raimundo Gonçalves de Oliveira Júnior, Raphaël Grougnet, Jullyana de Souza Siqueira Quintans, Lucindo José Quintans-Júnior. The protective effects of naringenin, a citrus flavonoid, non-complexed or complexed with hydroxypropyl-β-cyclodextrin against multiorgan damage caused by neonatal endotoxemia. International journal of biological macromolecules. 2024 Apr; 264(Pt 1):130500. doi: 10.1016/j.ijbiomac.2024.130500. [PMID: 38428770]
  • Yuying Zhao, Hanxu Tan, Juping Zhang, Dandan Zhan, Bowen Yang, Shicui Hong, Bo Pan, Neng Wang, Tongkai Chen, Yafei Shi, Zhiyu Wang. Developing liver-targeted naringenin nanoparticles for breast cancer endocrine therapy by promoting estrogen metabolism. Journal of nanobiotechnology. 2024 Mar; 22(1):122. doi: 10.1186/s12951-024-02356-0. [PMID: 38504208]
  • Ashutosh Pareek, Rupal Kothari, Aaushi Pareek, Yashumati Ratan, Pushpa Kashania, Vivek Jain, Philippe Jeandet, Parveen Kumar, Azmat Ali Khan, Amer M Alanazi, Madan Mohan Gupta. Development of a new inhaled swellable microsphere system for the dual delivery of naringenin-loaded solid lipid nanoparticles and doxofylline for the treatment of asthma. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2024 Feb; 193(?):106642. doi: 10.1016/j.ejps.2023.106642. [PMID: 37977235]
  • Weiyang Fan, Ziyan Xu, Jiashuo Zhang, Minyi Guan, Yuying Zheng, Yonggang Wang, Hao Wu, Weiwei Su, Peibo Li. Naringenin regulates cigarette smoke extract-induced extracellular vesicles from alveolar macrophage to attenuate the mouse lung epithelial ferroptosis through activating EV miR-23a-3p/ACSL4 axis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Feb; 124(?):155256. doi: 10.1016/j.phymed.2023.155256. [PMID: 38181527]
  • Tong Pan, Yen-Mei Lee, Eiki Takimoto, Kazutaka Ueda, Pang-Yen Liu, Hsin-Hsueh Shen. Inhibitory effects of naringenin on estrogen deficiency-induced obesity via regulation of mitochondrial dynamics and AMPK activation associated with white adipose tissue browning. Life sciences. 2024 Jan; 340(?):122453. doi: 10.1016/j.lfs.2024.122453. [PMID: 38272439]
  • Malgorzata Latos-Brozio, Anna Masek, Leszek Czechowski, Aleksandra Jastrzębska, Sebastian Miszczak. Effect of the Addition of Naringenin Derived from Citrus on the Properties of Epoxy Resin Compositions. Molecules (Basel, Switzerland). 2024 Jan; 29(2):. doi: 10.3390/molecules29020512. [PMID: 38276590]
  • Manuel Adrian Picos-Salas, Nayely Leyva-López, Pedro de Jesús Bastidas-Bastidas, Marilena Antunes-Ricardo, Luis Angel Cabanillas-Bojórquez, Miguel Angel Angulo-Escalante, J Basilio Heredia, Erick Paul Gutiérrez-Grijalva. Supercritical CO2 extraction of naringenin from Mexican oregano (Lippia graveolens): its antioxidant capacity under simulated gastrointestinal digestion. Scientific reports. 2024 01; 14(1):1146. doi: 10.1038/s41598-023-50997-2. [PMID: 38212400]
  • Luis Alberto Mejía-Manzano, César Iván Ortiz-Alcaráz, Laura E Parra Daza, Lina Suarez Medina, Teresa Vargas-Cortez, Miguel Fernández-Niño, Andrés Fernando González Barrios, José González-Valdez. Saccharomyces cerevisiae biofactory to produce naringenin using a systems biology approach and a bicistronic vector expression strategy in flavonoid production. Microbiology spectrum. 2024 Jan; 12(1):e0337423. doi: 10.1128/spectrum.03374-23. [PMID: 38088543]
  • Tsung-Ming Chang, Miao-Ching Chi, Yao-Chang Chiang, Chieh-Mo Lin, Mei-Ling Fang, Chiang-Wen Lee, Ju-Fang Liu, Yu Ru Kou. Promotion of ROS-mediated apoptosis, G2/M arrest, and autophagy by naringenin in non-small cell lung cancer. International journal of biological sciences. 2024; 20(3):1093-1109. doi: 10.7150/ijbs.85443. [PMID: 38322119]
  • Xiao Jin, Ling Jin, Bingxin Wu, Danping Xu. Naringenin protects myocardial ischemia/reperfusion injury by regulating miR-24-3p to inhibit cell death-inducing p53 target 1 expression. General physiology and biophysics. 2024 Jan; 43(1):13-23. doi: 10.4149/gpb_2023035. [PMID: 38312031]
  • Bo Peng, Lin Dai, Riccardo Iacovelli, Arnold J M Driessen, Kristina Haslinger. Heterologous Naringenin Production in the Filamentous Fungus Penicillium rubens. Journal of agricultural and food chemistry. 2023 Dec; 71(51):20782-20792. doi: 10.1021/acs.jafc.3c06755. [PMID: 38103029]
  • Pradeepti Ganesh, Vanishree Suresh, Manoj Kumar Narasimhan, Sarvesh Sabarathinam. A narrative review on Naringin and Naringenin as a possible bioenhancer in various drug-delivery formulations. Therapeutic delivery. 2023 Dec; 14(12):763-774. doi: 10.4155/tde-2023-0086. [PMID: 38088094]
  • Yungai Xiang, Meng Wang, Guo Yu, Lijing Wan, Yuxia Song, Yan Li, Xujing Geng, Li Tan. Naringenin alleviates the excessive lipid deposition of polycystic ovary syndrome rats and insulin-resistant adipocytes by promoting PKGIα. American journal of reproductive immunology (New York, N.Y. : 1989). 2023 12; 90(6):e13795. doi: 10.1111/aji.13795. [PMID: 38009056]
  • Hajar Salehi, Leilei Zhang, Fatma Nur Alp-Turgut, Busra Arikan, Fevzi Elbasan, Ceyda Ozfidan-Konakci, Melike Balcı, Gökhan Zengin, Evren Yildiztugay, Luigi Lucini. The exogenous application of naringenin and rosmarinic acid modulates functional traits in Lepidium sativum. Journal of the science of food and agriculture. 2023 Nov; ?(?):. doi: 10.1002/jsfa.13160. [PMID: 37994181]
  • H A Al-Amer, N S Al-Sowayan, H A Alfheeaid, S A Althwab, S A Alrobaish, E M Hamad, K H Musa, H M Mousa. Oral administration of naringenin and a mixture of coconut water and Arabic gum attenuate oxidative stress and lipid peroxidation in gentamicin-induced nephrotoxicity in rats. European review for medical and pharmacological sciences. 2023 Nov; 27(21):10427-10437. doi: 10.26355/eurrev_202311_34317. [PMID: 37975366]
  • A I Savko, T V Ilyich, A G Veiko, T A Kovalenia, E A Lapshina, I B Zavodnik. The flavonoids fisetin, apigenin, kaempferol, naringenin, naringin regulate respiratory activity and membrane potential of rat liver mitochondria and inhibit oxidative processes in erythrocytes. Biomeditsinskaia khimiia. 2023 Nov; 69(5):281-289. doi: 10.18097/pbmc20236905281. [PMID: 37937430]
  • Lei Zhang, Zhihui Yang, Xinyi Li, Yunqing Hua, Guanwei Fan, Feng He. Anti-atherosclerotic effects of naringenin and quercetin from Folium Artemisiae argyi by attenuating Interleukin-1 beta (IL-1β)/ matrix metalloproteinase 9 (MMP9): network pharmacology-based analysis and validation. BMC complementary medicine and therapies. 2023 Oct; 23(1):378. doi: 10.1186/s12906-023-04223-1. [PMID: 37880698]
  • Chenyang Yu, Duan Han, Jingfang Yu, Ran Zhu, Cuiyan Zhu, Fule Wang, Tiefeng Zhang. Exploration of potential targets and mechanisms of naringenin in the treatment of nonalcoholic fatty liver disease through network pharmacology. Medicine. 2023 Oct; 102(42):e35460. doi: 10.1097/md.0000000000035460. [PMID: 37861538]
  • Syeda Madiha, Zehra Batool, Sidrah Shahzad, Saiqa Tabassum, Laraib Liaquat, Asia Afzal, Sadia Sadir, Irfan Sajid, Bushra Jabeen Mehdi, Saara Ahmad, Saida Haider. Naringenin, a Functional Food Component, Improves Motor and Non-Motor Symptoms in Animal Model of Parkinsonism Induced by Rotenone. Plant foods for human nutrition (Dordrecht, Netherlands). 2023 Oct; ?(?):. doi: 10.1007/s11130-023-01103-4. [PMID: 37796415]
  • Haruna Nagayoshi, Norie Murayama, Vitchan Kim, Donghak Kim, Shigeo Takenaka, Hiroshi Yamazaki, F Peter Guengerich, Tsutomu Shimada. Oxidation of Naringenin, Apigenin, and Genistein by Human Family 1 Cytochrome P450 Enzymes and Comparison of Interaction of Apigenin with Human P450 1B1.1 and Scutellaria P450 82D.1. Chemical research in toxicology. 2023 Oct; ?(?):. doi: 10.1021/acs.chemrestox.3c00229. [PMID: 37783573]
  • Longkun Liu, Yoann Birling, Yan Zhao, Wenxin Ma, Yang Tang, Yuxin Sun, Xuehui Wang, Mingkun Yu, Hongsheng Bi, Jian-Ping Liu, Li Li, Zhaolan Liu. Mechanism of Chinese botanical drug Dizhi pill for myopia: An integrated study based on bioinformatics and network analysis. Medicine. 2023 Sep; 102(38):e34753. doi: 10.1097/md.0000000000034753. [PMID: 37747014]
  • Kübra Uçar, Zeynep Göktaş. Biological activities of naringenin: A narrative review based on in vitro and in vivo studies. Nutrition research (New York, N.Y.). 2023 Aug; 119(?):43-55. doi: 10.1016/j.nutres.2023.08.006. [PMID: 37738874]
  • Jiwei Mao, Marta Tous Mohedano, Jing Fu, Xiaowei Li, Quanli Liu, Jens Nielsen, Verena Siewers, Yun Chen. Fine-tuning of p-coumaric acid synthesis to increase (2S)-naringenin production in yeast. Metabolic engineering. 2023 Aug; 79(?):192-202. doi: 10.1016/j.ymben.2023.08.003. [PMID: 37611820]
  • Xu Lian, Kaidi Fan, Xuemei Qin, Yuetao Liu. Amalgamated Pharmacoinformatics Study to Investigate the Mechanism of Xiao Jianzhong Tang against Chronic Atrophic Gastritis. Current computer-aided drug design. 2023 Jul; ?(?):. doi: 10.2174/1573409919666230720141115. [PMID: 37475552]
  • Shimaa S Khaled, Hanan A Soliman, Mohammed Abdel-Gabbar, Noha A Ahmed, El-Shaymaa El-Nahass, Osama M Ahmed. Naringin and naringenin counteract taxol-induced liver injury in Wistar rats via suppression of oxidative stress, apoptosis and inflammation. Environmental science and pollution research international. 2023 Jul; ?(?):. doi: 10.1007/s11356-023-28454-4. [PMID: 37466839]
  • Gokul Sudhakaran, Abhirami Chandran, A R Sreekutty, S Madesh, Raman Pachaiappan, Bader O Almutairi, Selvaraj Arokiyaraj, Zulhisyam Abdul Kari, Guillermo Tellez-Isaias, Ajay Guru, Jesu Arockiaraj. Ophthalmic Intervention of Naringenin Decreases Vascular Endothelial Growth Factor by Counteracting Oxidative Stress and Cellular Damage in In Vivo Zebrafish. Molecules (Basel, Switzerland). 2023 Jul; 28(14):. doi: 10.3390/molecules28145350. [PMID: 37513223]
  • Seema Zargar, Nojood Altwaijry, Tanveer A Wani, Hamad M Alkahtani. Evaluation of the Possible Pathways Involved in the Protective Effects of Quercetin, Naringenin, and Rutin at the Gene, Protein and miRNA Levels Using In-Silico Multidimensional Data Analysis. Molecules (Basel, Switzerland). 2023 Jun; 28(13):. doi: 10.3390/molecules28134904. [PMID: 37446564]
  • Jie Wang, Ruoman Wu, Yiqiao Hua, Shijia Ling, Xiaole Xu. Naringenin ameliorates vascular senescence and atherosclerosis involving SIRT1 activation. The Journal of pharmacy and pharmacology. 2023 Jun; ?(?):. doi: 10.1093/jpp/rgad053. [PMID: 37343148]
  • Ravina Rai, Deepali Jat, Siddhartha Kumar Mishra. Naringenin ameliorates aluminum toxicity-induced testicular dysfunctions in mice by suppressing oxidative stress and histopathological alterations. Systems biology in reproductive medicine. 2023 May; ?(?):1-7. doi: 10.1080/19396368.2023.2203794. [PMID: 37204407]
  • Tiago Macedo, Fátima Paiva-Martins, Federico Ferreres, Nelson G M Gomes, Andreia P Oliveira, Ángel Gil-Izquierdo, Luísa Araújo, Patrícia Valentão, David M Pereira. Anti-inflammatory effects of naringenin 8-sulphonate from Parinari excelsa Sabine stem bark and its semi-synthetic derivatives. Bioorganic chemistry. 2023 May; 138(?):106614. doi: 10.1016/j.bioorg.2023.106614. [PMID: 37216893]
  • Emma R Wolf-Saxon, Chad C Moorman, Anthony Castro, Alfredo Ruiz, Jeremy P Mallari, Jason R Burke. Regulatory ligand binding in plant chalcone isomerase-like (CHIL) proteins. The Journal of biological chemistry. 2023 May; ?(?):104804. doi: 10.1016/j.jbc.2023.104804. [PMID: 37172720]
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