Naringin (BioDeep_00000000104)

 

Secondary id: BioDeep_00000302743

human metabolite PANOMIX_OTCML-2023 Chemicals and Drugs BioNovoGene_Lab2019 natural product


代谢物信息卡片


(2S)-7-[(2S,4S,5S,3R,6R)-3-((2S,6S,3R,4R,5R)-3,4,5-trihydroxy-6-methyl(2H-3,4, 5,6-tetrahydropyran-2-yloxy))-4,5-dihydroxy-6-(hydroxymethyl)(2H-3,4,5,6-tetra hydropyran-2-yloxy)]-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one

化学式: C27H32O14 (580.1792)
中文名称: 柚皮苷
谱图信息: 最多检出来源 Viridiplantae(plant) 23.36%

分子结构信息

SMILES: C1(O[C@H]2[C@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@@H](O)[C@H](O)[C@@H](CO)O2)C=C2O[C@]([H])(C3C=CC(O)=CC=3)CC(=O)C2=C(O)C=1
InChI: InChI=1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1

描述信息

Naringin, also known as naringoside or naringin hydrate, is a flavanone-7-O-glycoside between the flavanone naringenin and the disaccharide neohesperidose. Naringin belongs to the flavonoid family. Flavonoids consist of 15 carbon atoms in 3 rings, 2 of which must be benzene rings connected by a 3 carbon chain. Naringin contains the basic flavonoid structure along with one rhamnose and one glucose unit attached to its aglycone portion, called naringenin, at the 7-carbon position. The steric hindrance provided by the two sugar units makes naringin less potent than its aglycone counterpart, naringenin. Naringin is a bitter tasting compound. Naringin is found, on average, in the highest concentration within a few different foods, such as rosemaries, grapefruit/pummelo hybrids, and grapefruits and in a lower concentration in grape wines, pummelo, and beers. Naringin has also been detected, but not quantified in several different foods, such as citrus, limes, herbs and spices, common oregano, and mandarin orange (clementine, tangerine). Both naringin and hesperetin, which are the aglycones of naringin and hesperidin, occur naturally in citrus fruits. Naringin is the major flavonoid glycoside in grapefruit and gives grapefruit juice its bitter taste. Narinigin exerts a variety of pharmacological effects such as antioxidant activity, blood lipid-lowering, anticarcinogenic activity, and inhibition of selected cytochrome P450 enzymes including CYP3A4 and CYP1A2, which may result in several drug interactions in-vitro.
Naringin is a disaccharide derivative that is (S)-naringenin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as a metabolite, an antineoplastic agent and an anti-inflammatory agent. It is a disaccharide derivative, a dihydroxyflavanone, a member of 4-hydroxyflavanones, a (2S)-flavan-4-one and a neohesperidoside. It is functionally related to a (S)-naringenin.
Naringin is a natural product found in Podocarpus fasciculus, Citrus latipes, and other organisms with data available.
See also: Naringenin (related); Drynaria fortunei root (part of).
A disaccharide derivative that is (S)-naringenin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
obtained from citrus fruits, Clymenia polyandra (clymenia) and Origanum vulgare (oregano)
IPB_RECORD: 401; CONFIDENCE confident structure
Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities.
Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities.

同义名列表

73 个代谢物同义名

(2S)-7-[(2S,4S,5S,3R,6R)-3-((2S,6S,3R,4R,5R)-3,4,5-trihydroxy-6-methyl(2H-3,4, 5,6-tetrahydropyran-2-yloxy))-4,5-dihydroxy-6-(hydroxymethyl)(2H-3,4,5,6-tetra hydropyran-2-yloxy)]-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one; (S)-7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one; (S)-7-((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H-pyran-2-yloxy)-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one; (S)-7-((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)tetrahydro-2H-pyran-2-yloxy)-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one; (2S)-7-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-5-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; (2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one; (2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one; 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one; (2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one; 4H-1-Benzopyran-4-one,7-[[2-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-,(S)-; 4H-1-Benzopyran-4-one, 7-((2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-; 4H-1-Benzopyran-4-one, 7-((2-O-(6-deoxy-alpha-L-mannapyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl), (S)-; 7-((2-O-(6-DEOXY-.ALPHA.-L-MANNOPYRANOSYL)-.BETA.-D-GLUCOPYRANOSYL)OXY)-2,3-DIHYDRO-5-HYDROXY-2-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; (2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-1-benzopyran-7-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside; (2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside; (2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-betaD-glucopyranoside; 7-[[2-O-(6-Deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-5-hydroxy-2(S)-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 7-(2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyloxy)-2,3-dihydro-4,5,7-trihydroxyflavone; 5-Hydroxy-2-(4-hydroxyphenyl)-7-(2-O-alpha-L-rhamnopyranosyl-beta-D-glucopyranosyloxy)-4-chromanon; Naringenin 7-O-(alpha-L-rhamnosyl-(1->2)-beta-D-glucoside); Naringenin 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside]; naringenin 7-O-(alpha-L-rhamnosyl-(1,2)-beta-D-glucoside); Naringenin 7-O-alpha-L-rhamnosyl-(1->2)-beta-D-glucoside; Naringenin 7-O-[a-L-rhamnosyl-(1->2)-b-D-glucoside]; Naringenin 7-O-[α-L-rhamnosyl-(1->2)-β-D-glucoside]; Naringenin 7-O-a-L-rhamnosyl-(1->2)-b-D-glucoside; Naringenin 7-O-α-L-rhamnosyl-(1->2)-β-D-glucoside; 4,5,7-Trihydroxyflavanone-7-rhamnoglucoside; 4,5,7-trihydroxyflavanone 7-rhamnoglucoside; Naringenin-7-beta-neohesperidoside; Naringenine-7-rhamnosidoglucoside; Naringenin 7-O-neohesperidoside; NARINGENIN-7-RHAMNOGLUCOSIDE; Naringenin 7-Rhamnoglucoside; DFPMSGMNTNDNHN-ZPHOTFPESA-N; naringenin-7-hesperidoside; CITRUS NARINGININE [VANDF]; 45-diOH-Flavone-7-rhgluc; Naringin dihydrochalcone; Naringin (Naringoside); Naringenin Glycoside; AURANTIIN [WHO-DD]; Prestwick2_000467; Prestwick1_000467; NARINGIN (USP-RS); NARINGIN [USP-RS]; Prestwick0_000467; Prestwick3_000467; Naringin Hydrate; Naringin extract; NARINGIN [INCI]; UNII-N7TD9J649B; naringin sodium; Naringenin,(S); NARINGIN [MI]; DivK1c_000247; MEGxp0_001877; BPBio1_000632; (2S)-Naringin; KBio1_000247; ACon1_000139; IDI1_000247; Naringoside; N7TD9J649B; Nobiletin; AI3-19008; aurantiin; Cyclorel; Naringin; ZWN; (2S)-7-[(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-oxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one; Naringin; Naringin



数据库引用编号

35 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

10 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(9)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

222 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 ABCB1, BDNF, CDKN1A, CTNNB1, CYP3A4, MTOR, NOS2, PIK3C3, PPARG, PTGS2, TNFSF11, TP53
Peripheral membrane protein 4 ACHE, CYP1B1, MTOR, PTGS2
Endoplasmic reticulum membrane 5 CYP1B1, CYP3A4, HMGCR, MTOR, PTGS2
Cytoplasmic vesicle, autophagosome 1 PIK3C3
Nucleus 7 ACHE, CDKN1A, CTNNB1, MTOR, NOS2, PPARG, TP53
autophagosome 1 PIK3C3
cytosol 7 CDKN1A, CTNNB1, MTOR, NOS2, PIK3C3, PPARG, TP53
dendrite 2 BDNF, MTOR
nuclear body 1 CDKN1A
phagocytic vesicle 1 MTOR
phosphatidylinositol 3-kinase complex, class III 1 PIK3C3
centrosome 2 CTNNB1, TP53
nucleoplasm 7 ATP2B1, CDKN1A, CTNNB1, MTOR, NOS2, PPARG, TP53
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 5 ABCB1, ACHE, ATP2B1, CTNNB1, TNFSF11
Cytoplasmic side 1 MTOR
lamellipodium 1 CTNNB1
Multi-pass membrane protein 3 ABCB1, ATP2B1, HMGCR
Golgi apparatus membrane 1 MTOR
Synapse 3 ACHE, ATP2B1, CTNNB1
cell cortex 1 CTNNB1
cell junction 1 CTNNB1
cell surface 3 ABCB1, ACHE, ADIPOQ
glutamatergic synapse 3 ATP2B1, CTNNB1, PIK3C3
Golgi apparatus 1 ACHE
Golgi membrane 2 INS, MTOR
lysosomal membrane 1 MTOR
neuromuscular junction 1 ACHE
presynaptic membrane 2 ATP2B1, CTNNB1
synaptic vesicle 1 BDNF
Cytoplasm, cytosol 1 NOS2
Lysosome 1 MTOR
endosome 1 PIK3C3
plasma membrane 6 ABCB1, ACHE, ATP2B1, CTNNB1, NOS2, TNFSF11
synaptic vesicle membrane 1 ATP2B1
Membrane 12 ABCB1, ACHE, ATP2B1, BDNF, CTNNB1, CYP1B1, CYP3A4, HMGCR, MTOR, PIK3C3, TNFSF11, TP53
apical plasma membrane 1 ABCB1
axon 1 BDNF
basolateral plasma membrane 2 ATP2B1, CTNNB1
caveola 1 PTGS2
extracellular exosome 3 ABCB1, ATP2B1, CTNNB1
Lysosome membrane 1 MTOR
endoplasmic reticulum 4 ADIPOQ, HMGCR, PTGS2, TP53
extracellular space 7 ACHE, ADIPOQ, BDNF, CCL2, CXCL8, INS, TNFSF11
perinuclear region of cytoplasm 6 ACHE, BDNF, CDKN1A, CTNNB1, NOS2, PPARG
Schaffer collateral - CA1 synapse 1 CTNNB1
adherens junction 1 CTNNB1
apicolateral plasma membrane 1 CTNNB1
bicellular tight junction 1 CTNNB1
mitochondrion 2 CYP1B1, TP53
protein-containing complex 4 CDKN1A, CTNNB1, PTGS2, TP53
intracellular membrane-bounded organelle 4 ATP2B1, CYP1B1, CYP3A4, PPARG
Microsome membrane 4 CYP1B1, CYP3A4, MTOR, PTGS2
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Secreted 7 ACHE, ADIPOQ, BDNF, CCL2, CXCL8, INS, TNFSF11
extracellular region 7 ACHE, ADIPOQ, BDNF, CCL2, CXCL8, INS, TNFSF11
Mitochondrion outer membrane 1 MTOR
mitochondrial outer membrane 1 MTOR
Mitochondrion matrix 1 TP53
mitochondrial matrix 1 TP53
Extracellular side 1 ACHE
transcription regulator complex 2 CTNNB1, TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
Z disc 1 CTNNB1
beta-catenin destruction complex 1 CTNNB1
nucleolus 2 CDKN1A, TP53
Wnt signalosome 1 CTNNB1
midbody 1 PIK3C3
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
apical part of cell 1 CTNNB1
cell-cell junction 1 CTNNB1
Single-pass type II membrane protein 1 TNFSF11
postsynaptic membrane 1 CTNNB1
Apical cell membrane 1 ABCB1
Cytoplasm, perinuclear region 1 NOS2
Cytoplasm, cytoskeleton 2 CTNNB1, TP53
focal adhesion 1 CTNNB1
GABA-ergic synapse 1 PIK3C3
Cell junction, adherens junction 1 CTNNB1
flotillin complex 1 CTNNB1
Peroxisome 2 NOS2, PIK3C3
basement membrane 1 ACHE
collagen trimer 1 ADIPOQ
peroxisomal matrix 1 NOS2
peroxisomal membrane 1 HMGCR
Nucleus, PML body 2 MTOR, TP53
PML body 2 MTOR, TP53
collagen-containing extracellular matrix 1 ADIPOQ
fascia adherens 1 CTNNB1
lateral plasma membrane 2 ATP2B1, CTNNB1
axoneme 1 PIK3C3
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Late endosome 1 PIK3C3
receptor complex 1 PPARG
neuron projection 1 PTGS2
chromatin 2 PPARG, TP53
cell projection 1 ATP2B1
phagocytic vesicle membrane 1 PIK3C3
cell periphery 1 CTNNB1
Cytoplasm, cytoskeleton, cilium basal body 1 CTNNB1
spindle pole 1 CTNNB1
postsynaptic density, intracellular component 1 CTNNB1
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 ACHE
microvillus membrane 1 CTNNB1
site of double-strand break 1 TP53
nuclear envelope 1 MTOR
Endomembrane system 2 CTNNB1, MTOR
endosome lumen 1 INS
phagophore assembly site 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type I 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type II 1 PIK3C3
euchromatin 1 CTNNB1
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 ACHE
germ cell nucleus 1 TP53
replication fork 1 TP53
Peroxisome membrane 1 HMGCR
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 BDNF, INS, PTGS2
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
transport vesicle 1 INS
beta-catenin-TCF complex 1 CTNNB1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 ATP2B1
presynaptic endosome 1 PIK3C3
[Isoform 2]: Cytoplasm 1 TNFSF11
[Tumor necrosis factor ligand superfamily member 11, soluble form]: Secreted 1 TNFSF11
presynaptic active zone cytoplasmic component 1 CTNNB1
[Isoform 1]: Nucleus 1 TP53
synaptic cleft 1 ACHE
protein-DNA complex 1 CTNNB1
external side of apical plasma membrane 1 ABCB1
Cytoplasmic vesicle, phagosome 1 MTOR
catenin complex 1 CTNNB1
cyclin-dependent protein kinase holoenzyme complex 1 CDKN1A
postsynaptic endosome 1 PIK3C3
cortical cytoskeleton 1 NOS2
Autolysosome 1 PIK3C3
photoreceptor ribbon synapse 1 ATP2B1
PCNA-p21 complex 1 CDKN1A
beta-catenin-TCF7L2 complex 1 CTNNB1
[Isoform H]: Cell membrane 1 ACHE
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
beta-catenin-ICAT complex 1 CTNNB1
Scrib-APC-beta-catenin complex 1 CTNNB1


文献列表

  • Qi-Lin Huang, Li-Na Huang, Guan-Yu Zhao, Chen Liu, Xiang-Yi Pan, Zhao-Rong Li, Xiao-Han Jing, Zheng-Ying Qiu, Rui-Hua Xin. Naringin attenuates Actinobacillus pleuropneumoniae-induced acute lung injury via MAPK/NF-κB and Keap1/Nrf2/HO-1 pathway. BMC veterinary research. 2024 May; 20(1):204. doi: 10.1186/s12917-024-04055-2. [PMID: 38755662]
  • Yan Liu, Xiaohan Tang, Hailong Yuan, Rong Gao. Naringin Inhibits Macrophage Foam Cell Formation by Regulating Lipid Homeostasis and Metabolic Phenotype. Nutrients. 2024 Apr; 16(9):. doi: 10.3390/nu16091321. [PMID: 38732567]
  • Andreia Marinho, Catarina Leal Seabra, Sofia A C Lima, Alexandre Lobo-da-Cunha, Salette Reis, Cláudia Nunes. Empowering Naringin's Anti-Inflammatory Effects through Nanoencapsulation. International journal of molecular sciences. 2024 Apr; 25(8):. doi: 10.3390/ijms25084152. [PMID: 38673736]
  • Deepika Soni, Deepa Gandhi. Toxicity evaluation of silver nanoparticles synthesized from naringin flavonoid on human promyelocytic leukemic cells and human blood cells. Toxicology and industrial health. 2024 Mar; 40(3):125-133. doi: 10.1177/07482337241227244. [PMID: 38243157]
  • Qilin Huang, Wei Li, Xiaohan Jing, Chen Liu, Saad Ahmad, Lina Huang, Guanyu Zhao, Zhaorong Li, Zhengying Qiu, Ruihua Xin. Naringin's Alleviation of the Inflammatory Response Caused by Actinobacillus pleuropneumoniae by Downregulating the NF-κB/NLRP3 Signalling Pathway. International journal of molecular sciences. 2024 Jan; 25(2):. doi: 10.3390/ijms25021027. [PMID: 38256101]
  • Xiao-Han Jing, Guan-Yu Zhao, Gui-Bo Wang, Qi-Lin Huang, Wen-Shu Zou, Li-Na Huang, Wei Li, Zheng-Ying Qiu, Rui-Hua Xin. Naringin alleviates pneumonia caused by Klebsiella pneumoniae infection by suppressing NLRP3 inflammasome. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 Jan; 170(?):116028. doi: 10.1016/j.biopha.2023.116028. [PMID: 38113627]
  • Ziwei Yin, Xuefeng Hua, Minqiang Lu. Integrated Network Pharmacology and Metabolomics to Dissect the Mechanisms of Naringin for Treating Cervical Cancer. Combinatorial chemistry & high throughput screening. 2024; 27(5):754-764. doi: 10.2174/1386207326666230504124030. [PMID: 37143280]
  • Mustafa Ileriturk, Duygu Ileriturk, Ozge Kandemir, Nurhan Akaras, Hasan Simsek, Ender Erdogan, Fatih M Kandemir. Naringin attenuates oxaliplatin-induced nephrotoxicity and hepatotoxicity: A molecular, biochemical, and histopathological approach in a rat model. Journal of biochemical and molecular toxicology. 2024 Jan; 38(1):e23604. doi: 10.1002/jbt.23604. [PMID: 38037725]
  • Oluwaseun Esan, T O Ajibade, Chinomso Gift Ebirim, Moses Olusola Adetona, Ademola Adetokunbo Oyagbemi, Temidayo Olutayo Omobowale, Omolade Abodunrin Oladele, Adeolu Alex Adedapo, Oluwafemi Oguntibeju, Momoh Audu Yakubu, Evaristus Nwulia. Immunohistochemical and morphological changes associated with hepatic damage in lead acetate-induced toxicity and mitigatory properties of naringin in cockerel chicks. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. 2023 Dec; 38(2):239-246. doi: 10.54548/njps.v38i2.13. [PMID: 38696693]
  • Wei Xiong, Lingmei Yuan, Liangxia Wang, Guowen Qian, Chaoyi Liang, Bin Pan, Ling Guo, Wenqiang Wei, Xunxiang Qiu, Wenfang Deng, Zhikui Zeng. [Preparation of berberine-naringin dual drug-loaded composite microspheres and evaluation of their antibacterial-osteogenic properties]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. 2023 Dec; 37(12):1505-1513. doi: 10.7507/1002-1892.202308054. [PMID: 38130195]
  • Lingling Guan, Lan Guo, Heng Zhang, Hao Liu, Wenling Zhou, Yuanyuan Zhai, Xu Yan, Xiuli Men, Liang Peng. Naringin Protects against Non-Alcoholic Fatty Liver Disease by Promoting Autophagic Flux and Lipophagy. Molecular nutrition & food research. 2023 Dec; ?(?):e2200812. doi: 10.1002/mnfr.202200812. [PMID: 38054638]
  • Pradeepti Ganesh, Vanishree Suresh, Manoj Kumar Narasimhan, Sarvesh Sabarathinam. A narrative review on Naringin and Naringenin as a possible bioenhancer in various drug-delivery formulations. Therapeutic delivery. 2023 Dec; 14(12):763-774. doi: 10.4155/tde-2023-0086. [PMID: 38088094]
  • Meng-Chen Qin, Jun-Jie Li, Yan-Tao Zheng, Yun-Jia Li, Yu-Xue Zhang, Rou-Xuan Ou, Wei-Yi He, Jia-Min Zhao, Su-Tong Liu, Ming-Hao Liu, Hai-Yan Lin, Lei Gao. Naringin ameliorates liver fibrosis in zebrafish by modulating IDO1-mediated lipid metabolism and inflammatory infiltration. Food & function. 2023 Nov; ?(?):. doi: 10.1039/d3fo03858k. [PMID: 37930368]
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