3-O-Methylkaempferol (BioDeep_00000002775)

 

Secondary id: BioDeep_00000407050

human metabolite PANOMIX_OTCML-2023 natural product


代谢物信息卡片


5,7-dihydroxy-2-(4-hydroxyphenyl)-3-methoxy-4H-chromen-4-one

化学式: C16H12O6 (300.0634)
中文名称: 异山柰素
谱图信息: 最多检出来源 Viridiplantae(plant) 35.9%

分子结构信息

SMILES: c1(cc(c2c(c1)oc(c(c2=O)OC)c1ccc(cc1)O)O)O
InChI: InChI=1S/C16H12O6/c1-21-16-14(20)13-11(19)6-10(18)7-12(13)22-15(16)8-2-4-9(17)5-3-8/h2-7,17-19H,1H3

描述信息

3-o-methylkaempferol, also known as 5,7,4-trihydroxy-3-methoxyflavone or isokaempferide, is a member of the class of compounds known as 3-o-methylated flavonoids. 3-o-methylated flavonoids are flavonoids with methoxy groups attached to the C3 atom of the flavonoid backbone. Thus, 3-o-methylkaempferol is considered to be a flavonoid lipid molecule. 3-o-methylkaempferol is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 3-o-methylkaempferol can be found in common bean and coriander, which makes 3-o-methylkaempferol a potential biomarker for the consumption of these food products.

同义名列表

7 个代谢物同义名

5,7-dihydroxy-2-(4-hydroxyphenyl)-3-methoxy-4H-chromen-4-one; 5,7,4-trihydroxy-3-methoxyflavone; Kaempferol-3-O-methyl ether; Kaempferol 3-O-methyl ether; Kaempferol 3-methyl ether; 3-O-Methylkaempferol; Isokaempferide



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

13 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(12)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

483 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 ARG1, CCND3, CNP, CTNNB1, CYP2D6, CYP3A4, GUCY1A1, HPGDS, MYC, PTGS1, PTGS2, PTPN1, PTPRF
Peripheral membrane protein 3 PTGS1, PTGS2, PTPN1
Endoplasmic reticulum membrane 5 CYP2D6, CYP3A4, PTGS1, PTGS2, PTPN1
Nucleus 6 ARG1, CCND3, CSNK2A1, CTNNB1, MPO, MYC
cytosol 7 ARG1, CCND3, CSNK2A1, CTNNB1, GUCY1A1, HPGDS, PTPN1
centrosome 2 CCND3, CTNNB1
nucleoplasm 6 CCND3, CSNK2A1, CTNNB1, HPGDS, MPO, MYC
Cell membrane 2 CTNNB1, TNF
Lipid-anchor 1 CNP
Cytoplasmic side 1 PTPN1
lamellipodium 2 CTNNB1, STX2
Cytoplasmic granule 1 ARG1
Synapse 2 CNP, CTNNB1
cell cortex 1 CTNNB1
cell junction 1 CTNNB1
cell surface 1 TNF
glutamatergic synapse 3 CTNNB1, GUCY1A1, PTPN1
Golgi apparatus 1 PTGS1
lysosomal membrane 1 GAA
mitochondrial inner membrane 1 CNP
neuronal cell body 2 PTPRF, TNF
postsynapse 1 PTPN1
presynaptic membrane 1 CTNNB1
synaptic vesicle 1 STX2
Lysosome 2 GAA, MPO
plasma membrane 7 CSNK2A1, CTNNB1, GAA, IFNLR1, PTPRF, STX2, TNF
Membrane 10 CNP, CTNNB1, CYP2D6, CYP3A4, GAA, IFNLR1, MYC, PTPN1, PTPRF, STX2
basolateral plasma membrane 2 CTNNB1, STX2
caveola 1 PTGS2
extracellular exosome 6 CNP, CTNNB1, GAA, MPO, PTGS1, PTPRF
Lysosome membrane 1 GAA
endoplasmic reticulum 3 CYP2D6, PTGS2, PTPN1
extracellular space 5 ARG1, CNP, MPO, STX2, TNF
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 2 CNP, CTNNB1
Schaffer collateral - CA1 synapse 1 CTNNB1
adherens junction 1 CTNNB1
apicolateral plasma membrane 1 CTNNB1
bicellular tight junction 1 CTNNB1
mitochondrion 1 CYP2D6
protein-containing complex 5 CTNNB1, MYC, PTGS2, PTPN1, STX2
intracellular membrane-bounded organelle 8 CSNK2A1, CYP2D6, CYP3A4, GAA, HPGDS, MPO, PTGS1, STX2
Microsome membrane 4 CYP2D6, CYP3A4, PTGS1, PTGS2
Single-pass type I membrane protein 1 IFNLR1
Secreted 1 GAA
extracellular region 4 ARG1, GAA, MPO, TNF
Single-pass membrane protein 2 CYP2D6, PTPRF
mitochondrial outer membrane 1 CNP
mitochondrial matrix 1 PTPN1
transcription regulator complex 1 CTNNB1
photoreceptor outer segment 1 PTGS1
external side of plasma membrane 1 TNF
Z disc 1 CTNNB1
beta-catenin destruction complex 1 CTNNB1
nucleolus 1 MYC
Wnt signalosome 1 CTNNB1
Early endosome 1 PTPN1
apical part of cell 1 CTNNB1
cell-cell junction 1 CTNNB1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
postsynaptic membrane 1 CTNNB1
presynaptic active zone membrane 1 STX2
Membrane raft 1 TNF
Cytoplasm, cytoskeleton 1 CTNNB1
focal adhesion 1 CTNNB1
microtubule 1 CNP
GABA-ergic synapse 1 GUCY1A1
Cell junction, adherens junction 1 CTNNB1
flotillin complex 1 CTNNB1
PML body 1 CSNK2A1
secretory granule 1 MPO
fascia adherens 1 CTNNB1
lateral plasma membrane 1 CTNNB1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 3 PTGS1, PTGS2, PTPRF
chromatin 1 MYC
phagocytic cup 1 TNF
cell periphery 1 CTNNB1
Cytoplasm, cytoskeleton, cilium basal body 1 CTNNB1
mitochondrial crista 1 PTPN1
Nucleus, nucleolus 1 MYC
spindle pole 1 CTNNB1
postsynaptic density, intracellular component 1 CTNNB1
microvillus membrane 1 CTNNB1
nuclear envelope 1 MYC
Endomembrane system 4 CTNNB1, PTGS1, PTPN1, STX2
endosome lumen 1 PTPN1
sorting endosome 1 PTPN1
microvillus 1 CNP
Nucleus, nucleoplasm 1 MYC
tertiary granule membrane 1 GAA
Melanosome 1 CNP
euchromatin 1 CTNNB1
pseudopodium 1 CNP
azurophil granule 1 MPO
SNARE complex 1 STX2
endoplasmic reticulum lumen 1 PTGS2
specific granule lumen 1 ARG1
azurophil granule membrane 1 GAA
RNA polymerase II transcription repressor complex 1 MYC
beta-catenin-TCF complex 1 CTNNB1
azurophil granule lumen 2 ARG1, MPO
presynaptic active zone cytoplasmic component 1 CTNNB1
phagocytic vesicle lumen 1 MPO
Sin3-type complex 1 CSNK2A1
protein-DNA complex 1 CTNNB1
ficolin-1-rich granule membrane 1 GAA
Rough endoplasmic reticulum 1 MYC
catenin complex 1 CTNNB1
guanylate cyclase complex, soluble 1 GUCY1A1
cyclin-dependent protein kinase holoenzyme complex 1 CCND3
Myc-Max complex 1 MYC
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
myelin sheath abaxonal region 1 CNP
myelin sheath adaxonal region 1 CNP
autolysosome lumen 1 GAA
cyclin D3-CDK4 complex 1 CCND3
beta-catenin-TCF7L2 complex 1 CTNNB1
cytoplasmic side of endoplasmic reticulum membrane 1 PTPN1
protein kinase CK2 complex 1 CSNK2A1
cyclin D3-CDK6 complex 1 CCND3
beta-catenin-ICAT complex 1 CTNNB1
Scrib-APC-beta-catenin complex 1 CTNNB1
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
nucleoplasmic reticulum 1 MYC


文献列表

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