NCBI Taxonomy: 41516

Centaurea clementei (ncbi_taxid: 41516)

found 19 associated metabolites at species taxonomy rank level.

Ancestor: Centaurea

Child Taxonomies: none taxonomy data.

dinatin

Scutellarein 6-methyl ether

C16H12O6 (300.0634)


Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC50 of 2.71 μM. Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC50 of 2.71 μM.

   

3-O-Methylkaempferol

5,7-dihydroxy-2-(4-hydroxyphenyl)-3-methoxy-4H-chromen-4-one

C16H12O6 (300.0634)


3-o-methylkaempferol, also known as 5,7,4-trihydroxy-3-methoxyflavone or isokaempferide, is a member of the class of compounds known as 3-o-methylated flavonoids. 3-o-methylated flavonoids are flavonoids with methoxy groups attached to the C3 atom of the flavonoid backbone. Thus, 3-o-methylkaempferol is considered to be a flavonoid lipid molecule. 3-o-methylkaempferol is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 3-o-methylkaempferol can be found in common bean and coriander, which makes 3-o-methylkaempferol a potential biomarker for the consumption of these food products.

   

Scutellarein

6-hydroxyapigenin

C15H10O6 (286.0477)


Scutellarein is a natural flavonoid compound with anti-inflammatory effects. Scutellarein is a natural flavonoid compound with anti-inflammatory effects.

   

Negletein

5,6-dihydroxy-7-methoxy-2-phenylchromen-4-one

C16H12O5 (284.0685)


Negletein is a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 and 10.8 μM, respectively[1]. Negletein is a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 and 10.8 μM, respectively[1].

   

Negletein

4H-1-Benzopyran-4-one, 5,6-dihydroxy-7-methoxy-2-phenyl-

C16H12O5 (284.0685)


Negletein is a member of flavonoids and an ether. Negletein is a natural product found in Stachys palustris, Desmos chinensis, and other organisms with data available. Negletein is a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 and 10.8 μM, respectively[1]. Negletein is a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 and 10.8 μM, respectively[1].

   

Scutellarein

(2S)-2,3-dihydro-5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

C15H10O6 (286.0477)


Scutellarein is flavone substituted with hydroxy groups at C-4, -5, -6 and -7. It has a role as a metabolite. It is functionally related to an apigenin. It is a conjugate acid of a scutellarein(1-). Scutellarein is a natural product found in Scoparia dulcis, Artemisia douglasiana, and other organisms with data available. Flavone substituted with hydroxy groups at C-4, -5, -6 and -7. Scutellarein, also known as 6-hydroxyapigenin or 4,5,6,7-tetrahydroxyflavanone, is a member of the class of compounds known as flavones. Flavones are flavonoids with a structure based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one). Thus, scutellarein is considered to be a flavonoid lipid molecule. Scutellarein is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Scutellarein can be synthesized from apigenin. Scutellarein is also a parent compound for other transformation products, including but not limited to, scutellarin, 4,6-dihydroxy-5,7-dimethoxyflavone, and 6-hydroxy-4,5,7-trimethoxyflavone. Scutellarein is a bitter tasting compound found in mexican oregano and sweet orange, which makes scutellarein a potential biomarker for the consumption of these food products. Scutellarein is a flavone that can be found in Scutellaria lateriflora and other members of the genus Scutellaria, as well as the fern Asplenium belangeri . Scutellarein is a natural flavonoid compound with anti-inflammatory effects. Scutellarein is a natural flavonoid compound with anti-inflammatory effects.

   

Hispidulin

4H-1-Benzopyran-4-one, 5, 7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-

C16H12O6 (300.0634)


Hispidulin is a monomethoxyflavone that is scutellarein methylated at position 6. It has a role as an apoptosis inducer, an anti-inflammatory agent, an antioxidant, an anticonvulsant, an antineoplastic agent and a plant metabolite. It is a trihydroxyflavone and a monomethoxyflavone. It is functionally related to a scutellarein. Hispidulin (4,5,7-trihydroxy-6-methoxyflavone) is a potent benzodiazepine (BZD) receptor ligand with positive allosteric properties. Hispidulin is a natural product found in Eupatorium cannabinum, Eupatorium perfoliatum, and other organisms with data available. See also: Arnica montana Flower (part of). A monomethoxyflavone that is scutellarein methylated at position 6. 6-methylscutellarein, also known as 4,5,7-trihydroxy-6-methoxyflavone or dinatin, is a member of the class of compounds known as 6-o-methylated flavonoids. 6-o-methylated flavonoids are flavonoids with methoxy groups attached to the C6 atom of the flavonoid backbone. Thus, 6-methylscutellarein is considered to be a flavonoid lipid molecule. 6-methylscutellarein is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 6-methylscutellarein can be found in a number of food items such as italian oregano, common sage, sunflower, and common thyme, which makes 6-methylscutellarein a potential biomarker for the consumption of these food products. Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC50 of 2.71 μM. Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC50 of 2.71 μM.

   

dinatin

4H-1-Benzopyran-4-one, 5, 7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-

C16H12O6 (300.0634)


Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC50 of 2.71 μM. Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC50 of 2.71 μM.

   

Isokaempferide

5,7,4-trihydroxy-3-methoxyflavone

C16H12O6 (300.0634)


   

5,7-dihydroxy-2-(4-hydroxyphenyl)-3-methoxy-4H-chromen-4-one

5,7-dihydroxy-2-(4-hydroxyphenyl)-3-methoxy-4H-chromen-4-one

C16H12O6 (300.0634)


   

Flavonoid

4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-(4-hydroxyphenyl)-

C15H10O6 (286.0477)


Scutellarein is a natural flavonoid compound with anti-inflammatory effects. Scutellarein is a natural flavonoid compound with anti-inflammatory effects.

   

8-hydroxy-4'-methyl-6,9-dimethylidene-2-oxo-octahydrospiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

8-hydroxy-4'-methyl-6,9-dimethylidene-2-oxo-octahydrospiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

C21H26O7 (390.1678)


   

(3s,3ar,4s,4's,6ar,8s,9ar,9bs)-8-hydroxy-4'-methyl-6,9-dimethylidene-2-oxo-octahydrospiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

(3s,3ar,4s,4's,6ar,8s,9ar,9bs)-8-hydroxy-4'-methyl-6,9-dimethylidene-2-oxo-octahydrospiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

C21H26O7 (390.1678)


   

(3s,3ar,4s,4'r,6ar,8s,9ar,9br)-8-hydroxy-4'-methyl-6,9-dimethylidene-2-oxo-octahydrospiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

(3s,3ar,4s,4'r,6ar,8s,9ar,9br)-8-hydroxy-4'-methyl-6,9-dimethylidene-2-oxo-octahydrospiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

C21H26O7 (390.1678)


   

(3s,3as,4s,4'r,6ar,8s,9s,9ar,9bs)-8-hydroxy-4',9-dimethyl-6-methylidene-2-oxo-octahydro-3ah-spiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

(3s,3as,4s,4'r,6ar,8s,9s,9ar,9bs)-8-hydroxy-4',9-dimethyl-6-methylidene-2-oxo-octahydro-3ah-spiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

C21H28O7 (392.1835)


   

(3s,3ar,4s,4's,6ar,8s,9ar,9br)-8-hydroxy-4'-methyl-6,9-dimethylidene-2-oxo-octahydrospiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

(3s,3ar,4s,4's,6ar,8s,9ar,9br)-8-hydroxy-4'-methyl-6,9-dimethylidene-2-oxo-octahydrospiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

C21H26O7 (390.1678)


   

(3s,3ar,4s,4'r,6ar,8s,9ar,9bs)-8-hydroxy-4'-methyl-6,9-dimethylidene-2-oxo-octahydrospiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

(3s,3ar,4s,4'r,6ar,8s,9ar,9bs)-8-hydroxy-4'-methyl-6,9-dimethylidene-2-oxo-octahydrospiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

C21H26O7 (390.1678)


   

8-hydroxy-4',9-dimethyl-6-methylidene-2-oxo-octahydro-3ah-spiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

8-hydroxy-4',9-dimethyl-6-methylidene-2-oxo-octahydro-3ah-spiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

C21H28O7 (392.1835)


   

(3s,3ar,4s,4'r,6ar,8s,9s,9ar,9br)-8-hydroxy-4',9-dimethyl-6-methylidene-2-oxo-octahydro-3ah-spiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

(3s,3ar,4s,4'r,6ar,8s,9s,9ar,9br)-8-hydroxy-4',9-dimethyl-6-methylidene-2-oxo-octahydro-3ah-spiro[azuleno[4,5-b]furan-3,2'-oxetan]-4-yl 2-(hydroxymethyl)prop-2-enoate

C21H28O7 (392.1835)