Corosolic_acid (BioDeep_00000230306)
Main id: BioDeep_00000231231
PANOMIX_OTCML-2023 Antitumor activity
代谢物信息卡片
(1S,2R,4aS,6aS,6bR,8aR,10R,11R,12aR,12bR,14bS)-10,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
化学式: C30H48O4 (472.3552408)
中文名称: 科罗索酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1C)C)C(=O)O
InChI: InChI=1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,1-7H3,(H,33,34)/t17-,18+,20-,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
描述信息
Corosolic acid is a triterpenoid. It has a role as a metabolite.
Corosolic acid is a natural product found in Ternstroemia gymnanthera, Cunila lythrifolia, and other organisms with data available.
See also: Lagerstroemia speciosa leaf (part of).
A natural product found particularly in Rhododendron species and Eriobotrya japonica.
Corosolic acid (Colosolic acid) isolated from the fruit of Cratoegus pinnatifida var. psilosa, was reported to have anticancer activity.
Corosolic acid (Colosolic acid) isolated from the fruit of Cratoegus pinnatifida var. psilosa, was reported to have anticancer activity.
同义名列表
32 个代谢物同义名
(1S,2R,4aS,6aS,6bR,8aR,10R,11R,12aR,12bR,14bS)-10,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid; (1S,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid; Corosolic acid, United States Pharmacopeia (USP) Reference Standard; URS-12-EN-28-OIC ACID, 2,3-DIHYDROXY-, (2.ALPHA.,3.BETA.)-; Corosolic acid from Lagerstroemia speciosa, >=98\\% (HPLC); Urs-12-en-28-oic acid, 2,3-dihydroxy-, (2alpha,3beta)-; 2alpha,2beta-dihydroxy-18beta-ursan-12-ene-28-oic acid; (2alpha,3beta)-2,3-Dihydroxyurs-12-en-28-oic acid; COROSOLIC ACID (CONSTITUENT OF BANABA LEAF) [DSC]; 2alpha,3beta-dihydroxyurs-12-en-28-oic acid; COROSOLIC ACID (CONSTITUENT OF BANABA LEAF); Colosolic acid; Corsolic acid; Glucosol; Corosolic acid, analytical standard; BENZYL5-AMINOPYRAZOLE-4-CARBOXYLATE; Ursolic acid (2-alpha-hydroxy-); 2-.ALPHA.-HYDROXYURSOLIC ACID; 2alpha-hydroxyursoloic acid; HFGSQOYIOKBQOW-ZSDYHTTISA-N; 2-alpha-Hydroxyursolic acid; 2alpha-Hydroxyursolic acid; COROSOLIC ACID (USP-RS); COROSOLIC ACID [USP-RS]; 2a-hydroxyursolic acid; UNII-AMX2I57A98; Corosolic acid; Corosolic-acid; Colosolic acid; Corsolic acid; Colosic acid; AMX2I57A98; Corosolic; Glucosol
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:67895
- PubChem: 6918774
- ChEMBL: CHEMBL391533
- Wikipedia: Corosolic_acid
- MeSH: corosolic acid
- ChemIDplus: 0004547244
- chemspider: 5293965
- CAS: 4547-24-4
- medchemexpress: HY-N0280
- MetaboLights: MTBLC67895
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
4 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Karuna Surendran, Siya Pradeep, Padmesh Pandaram Pillai. Comparative transcriptome and metabolite profiling reveal diverse pattern of CYP-TS gene expression during corosolic acid biosynthesis in Lagerstroemia speciosa (L.) Pers.
Plant cell reports.
2024 Apr; 43(5):122. doi:
10.1007/s00299-024-03203-0. [PMID: 38642121] - Sanghee Han, Sung-Lyul Lim, Hail Kim, Hyunjin Choi, Min Young Lee, Sun-Yup Shim, Duc Dat Le, In Jin Ha, Mina Lee, Seok-Geun Lee. Ethyl acetate fraction of Osmanthus fragrans var. aurantiacus and its triterpenoids suppress proliferation and survival of colorectal cancer cells by inhibiting NF-κB and COX2.
Journal of ethnopharmacology.
2024 Jan; 319(Pt 3):117362. doi:
10.1016/j.jep.2023.117362. [PMID: 38380575] - Anfang Cui, Xiangling Li, Xiaolei Ma, Zhigang Song, Xiao Wang, Chao Wang, Yong Xia. Quantitative transcriptomic and proteomic analysis reveals corosolic acid inhibiting bladder cancer via suppressing cell cycle and inducing mitophagy in vitro and in vivo.
Toxicology and applied pharmacology.
2023 Nov; 480(?):116749. doi:
10.1016/j.taap.2023.116749. [PMID: 37939859] - Tsai-Kun Wu, Tung-Wei Hung, Yong-Syuan Chen, Ying-Ru Pan, Yi-Hsien Hsieh, Jen-Pi Tsai. Corosolic acid inhibits metastatic response of human renal cell carcinoma cells by modulating ERK/MMP2 signaling.
Environmental toxicology.
2023 Oct; ?(?):. doi:
10.1002/tox.23999. [PMID: 37860891] - Sylvia Sinelius, Jullietta Lady, Michellina Yunardy, Enty Tjoa, Agustina D R Nurcahyanti. Antibacterial activity of Lagerstreomia speciosa and its active compound, corosolic acid, enhances cefotaxime inhibitory activity against Staphylococcus aureus.
Journal of applied microbiology.
2023 Aug; 134(8):. doi:
10.1093/jambio/lxad171. [PMID: 37541956] - Feifeng Tang, Yingxiu Peng, Jingjin Liu, Wenhui Gao, Yanfeng Xu. Integrating network pharmacology and experimental models to examine the mechanisms of corosolic acid in preventing hepatocellular carcinoma progression through activation PERK-eIF2a-ATF4 signaling.
Naunyn-Schmiedeberg's archives of pharmacology.
2023 Jun; ?(?):. doi:
10.1007/s00210-023-02560-z. [PMID: 37294427] - Fei-Feng Tang, Long Liu, Xiao-Ting Tian, Ning Li, Ying-Xiu Peng, Chun-Mei Qian, Ting-Ting Jia, Jing-Jin Liu, Wen-Hui Gao, Yan-Feng Xu. Network pharmacological analysis of corosolic acid reveals P4HA2 inhibits hepatocellular carcinoma progression.
BMC complementary medicine and therapies.
2023 May; 23(1):171. doi:
10.1186/s12906-023-04008-6. [PMID: 37248456] - Ziyan Guo, Qiufang Jing, Zhongyu Xu, Dahe Zhang, Wenyun Zheng, Fuzheng Ren. Corosolic acid-modified lipid nanoparticles as delivery carriers for DNA vaccines against avian influenza.
International journal of pharmaceutics.
2023 May; 638(?):122914. doi:
10.1016/j.ijpharm.2023.122914. [PMID: 37028571] - Faisal K Alkholifi, Sushma Devi, Hasan S Yusufoglu, Aftab Alam. The Cardioprotective Effect of Corosolic Acid in the Diabetic Rats: A Possible Mechanism of the PPAR-γ Pathway.
Molecules (Basel, Switzerland).
2023 Jan; 28(3):. doi:
10.3390/molecules28030929. [PMID: 36770602] - Huiqiang Wei, Jianghong Guo, Xiao Sun, Wenfeng Gou, Hongxin Ning, Haihua Shang, Qiang Liu, Wenbin Hou, Yiliang Li. Discovery of Natural Ursane-type SENP1 Inhibitors and the Platinum Resistance Reversal Activity Against Human Ovarian Cancer Cells: A Structure-Activity Relationship Study.
Journal of natural products.
2022 05; 85(5):1248-1255. doi:
10.1021/acs.jnatprod.1c01166. [PMID: 35500202] - Mingming Jin, Yue Wu, Yuqing Lou, Xiyu Liu, Yitian Dai, Wenxiao Yang, Congbiao Liu, Gang Huang. Corosolic acid reduces A549 and PC9 cell proliferation, invasion, and chemoresistance in NSCLC via inducing mitochondrial and liposomal oxidative stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Dec; 144(?):112313. doi:
10.1016/j.biopha.2021.112313. [PMID: 34678723] - Xu-Ping Qian, Xue-Hui Zhang, Lu-Ning Sun, Wei-Fan Xing, Yu Wang, Shi-Yu Sun, Meng-Yuan Ma, Zi-Ping Cheng, Zu-Dong Wu, Chen Xing, Bei-Ning Chen, Yong-Qing Wang. Corosolic acid and its structural analogs: A systematic review of their biological activities and underlying mechanism of action.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2021 Oct; 91(?):153696. doi:
10.1016/j.phymed.2021.153696. [PMID: 34456116] - Congcong Zhang, Yongjie Niu, Zhixian Wang, Xin Xu, Yan Li, Lifang Ma, Jiayi Wang, Yongchun Yu. Corosolic acid inhibits cancer progression by decreasing the level of CDK19-mediated O-GlcNAcylation in liver cancer cells.
Cell death & disease.
2021 09; 12(10):889. doi:
10.1038/s41419-021-04164-y. [PMID: 34588426] - Guancheng Liu, Zhe Cui, Xiaoyan Gao, Huizhe Liu, Linghe Wang, Jinyan Gong, Ao Wang, Jianxiu Zhang, Qianqian Ma, Yuan Huang, Guangchun Piao, Haidan Yuan. Corosolic acid ameliorates non-alcoholic steatohepatitis induced by high-fat diet and carbon tetrachloride by regulating TGF-β1/Smad2, NF-κB, and AMPK signaling pathways.
Phytotherapy research : PTR.
2021 Sep; 35(9):5214-5226. doi:
10.1002/ptr.7195. [PMID: 34213784] - Anna Magiera, Anna Marchelak, Piotr Michel, Aleksandra Owczarek, Monika A Olszewska. Lipophilic extracts from leaves, inflorescences and fruits of Prunus padus L. as potential sources of corosolic, ursolic and oleanolic acids with anti-inflammatory activity.
Natural product research.
2021 Jul; 35(13):2263-2268. doi:
10.1080/14786419.2019.1666385. [PMID: 31533493] - Liu Liu, Haobin Li, Kaiwen Hu, Qinglong Xu, Xiaoan Wen, Keguang Cheng, Caiping Chen, Haoliang Yuan, Liang Dai, Hongbin Sun. Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid.
European journal of medicinal chemistry.
2021 Jan; 209(?):112932. doi:
10.1016/j.ejmech.2020.112932. [PMID: 33131725] - Daniela Alejandra Torres-Ortiz, Rodríguez-deLeón Eloy, Bah Moustapha, Ibarra-Alvarado César, Mercado-Silva Edmundo, Castro-Ruiz Jesús Eduardo, Rivera-Pastrana Dulce María. Vasorelaxing effect and possible chemical markers of the flowers of the Mexican Crataegus gracilior.
Natural product research.
2020 Dec; 34(24):3522-3525. doi:
10.1080/14786419.2019.1577833. [PMID: 30864868] - Rohit Singh Thakur, Ezhilarasan Devaraj. Lagerstroemia speciosa (L.) Pers. triggers oxidative stress mediated apoptosis via intrinsic mitochondrial pathway in HepG2 cells.
Environmental toxicology.
2020 Nov; 35(11):1225-1233. doi:
10.1002/tox.22987. [PMID: 32697429] - Jian-Xiu Zhang, Wei-Jun Feng, Guan-Cheng Liu, Qian-Qian Ma, Hai-Lan Li, Xiao-Yan Gao, Hui-Zhe Liu, Guang-Chun Piao, Hai-Dan Yuan. Corosolic Acid Attenuates Hepatic Lipid Accumulation and Inflammatory Response via AMPK/SREBPs and NF-κB/MAPK Signaling Pathways.
The American journal of Chinese medicine.
2020; 48(3):579-595. doi:
10.1142/s0192415x20500299. [PMID: 32329643] - T Rohit Singh, D Ezhilarasan. Ethanolic Extract of Lagerstroemia Speciosa (L.) Pers., Induces Apoptosis and Cell Cycle Arrest in HepG2 Cells.
Nutrition and cancer.
2020; 72(1):146-156. doi:
10.1080/01635581.2019.1616780. [PMID: 31149840] - Chiobouaphong Phakeovilay, Sandra Bourgeade-Delmas, Pierre Perio, Alexis Valentin, François Chassagne, Eric Deharo, Karine Reybier, Guillaume Marti. Antileishmanial Compounds Isolated from Psidium Guajava L. Using a Metabolomic Approach.
Molecules (Basel, Switzerland).
2019 Dec; 24(24):. doi:
10.3390/molecules24244536. [PMID: 31835791] - Mengting Ni, Junhui Pan, Xing Hu, Deming Gong, Guowen Zhang. Inhibitory effect of corosolic acid on α-glucosidase: kinetics, interaction mechanism, and molecular simulation.
Journal of the science of food and agriculture.
2019 Oct; 99(13):5881-5889. doi:
10.1002/jsfa.9862. [PMID: 31206698] - Biying Zhang, Yawen Lu, Ping Li, Xiaodong Wen, Jie Yang. Study on the absorption of corosolic acid in the gastrointestinal tract and its metabolites in rats.
Toxicology and applied pharmacology.
2019 09; 378(?):114600. doi:
10.1016/j.taap.2019.114600. [PMID: 31150656] - Mir Babak Bahadori, Somayeh Vandghanooni, Leila Dinparast, Morteza Eskandani, Seyed Abdulmajid Ayatollahi, Athar Ata, Hossein Nazemiyeh. Triterpenoid corosolic acid attenuates HIF-1 stabilization upon cobalt (II) chloride-induced hypoxia in A549 human lung epithelial cancer cells.
Fitoterapia.
2019 Apr; 134(?):493-500. doi:
10.1016/j.fitote.2019.03.013. [PMID: 30898728] - Shuwen Xu, Gang Wang, Wei Peng, Yandi Xu, Yu Zhang, Ying Ge, Yue Jing, Zhunan Gong. Corosolic acid isolated from Eriobotrya japonica leaves reduces glucose level in human hepatocellular carcinoma cells, zebrafish and rats.
Scientific reports.
2019 03; 9(1):4388. doi:
10.1038/s41598-019-40934-7. [PMID: 30867526] - Zhubo Dai, Yun Liu, Zhoutong Sun, Dong Wang, Ge Qu, Xiaolin Ma, Feiyu Fan, Lili Zhang, Shoulian Li, Xueli Zhang. Identification of a novel cytochrome P450 enzyme that catalyzes the C-2α hydroxylation of pentacyclic triterpenoids and its application in yeast cell factories.
Metabolic engineering.
2019 01; 51(?):70-78. doi:
10.1016/j.ymben.2018.10.001. [PMID: 30339834] - Seon Min Woo, Seung Un Seo, Kyoung-Jin Min, Seung-Soon Im, Ju-Ock Nam, Jong-Soo Chang, Shin Kim, Jong-Wook Park, Taeg Kyu Kwon. Corosolic Acid Induces Non-Apoptotic Cell Death through Generation of Lipid Reactive Oxygen Species Production in Human Renal Carcinoma Caki Cells.
International journal of molecular sciences.
2018 Apr; 19(5):. doi:
10.3390/ijms19051309. [PMID: 29702597] - Mahmoud A Al-Qudah, Noor K Otoom, Hala I Al-Jaber, Ayman M Saleh, Musa H Abu Zarga, Fatma U Afifi, Sultan T Abu Orabi. New flavonol glycoside from Scabiosa prolifera L. aerial parts with in vitro antioxidant and cytotoxic activities.
Natural product research.
2017 Dec; 31(24):2865-2874. doi:
10.1080/14786419.2017.1305377. [PMID: 28338344] - Qi-Lai Cheng, Hong-Liang Li, Ying-Chen Li, Zhao-Wen Liu, Xiao-Hua Guo, Yi-Jian Cheng. CRA(Crosolic Acid) isolated from Actinidia valvata Dunn.Radix induces apoptosis of human gastric cancer cell line BGC823 in vitro via down-regulation of the NF-κB pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2017 Jul; 105(?):475-485. doi:
10.1016/j.fct.2017.05.021. [PMID: 28506699] - Chung Sub Kim, Lalita Subedi, Joonseok Oh, Sun Yeou Kim, Sang Un Choi, Kang Ro Lee. Bioactive Triterpenoids from the Twigs of Chaenomeles sinensis.
Journal of natural products.
2017 04; 80(4):1134-1140. doi:
10.1021/acs.jnatprod.7b00111. [PMID: 28358502] - Yu-lu Li, Hua-nian Dai, Guo-xu Ma, Wen Zhang, Tong-yu Wu, Yun-qing Wang, Jie-ming Zou, Xiao-qing Zhong, Yan-lin Zhou, Jing-quan Yuan, Xu-dong Xu, Wei Yi. [A new triterpenic acid from the roots of Rosa laevigata].
Yao xue xue bao = Acta pharmaceutica Sinica.
2017 Mar; 52(3):425-9. doi:
". [PMID: 29979854] - Yanfeng Xu, Yinghui Zhao, Yanli Xu, Yu Guan, Xiao Zhang, Yan Chen, Qi Wu, Guoqing Zhu, Yuxin Chen, Fenyong Sun, Jiayi Wang, Yongchun Yu. Blocking inhibition to YAP by ActinomycinD enhances anti-tumor efficacy of Corosolic acid in treating liver cancer.
Cellular signalling.
2017 01; 29(?):209-217. doi:
10.1016/j.cellsig.2016.11.001. [PMID: 27836738] - Chen Wang, Ping Wu, Shuai Tian, Jinghua Xue, Liangxiong Xu, Hanxiang Li, Xiaoyi Wei. Bioactive Pentacyclic Triterpenoids from the Leaves of Cleistocalyx operculatus.
Journal of natural products.
2016 11; 79(11):2912-2923. doi:
10.1021/acs.jnatprod.6b00715. [PMID: 27797185] - Jun Cao, Li-Qing Peng, Jing-Jing Xu. Microcrystalline cellulose based matrix solid phase dispersion microextration for isomeric triterpenoid acids in loquat leaves by ultrahigh-performance liquid chromatography and quadrupole time-of-flight mass spectrometry.
Journal of chromatography. A.
2016 Nov; 1472(?):16-26. doi:
10.1016/j.chroma.2016.10.034. [PMID: 27776775] - Xiao-Qiang Li, Wen Tian, Xiao-Xiao Liu, Kai Zhang, Jun-Cheng Huo, Wen-Juan Liu, Ping Li, Xiong Xiao, Ming-Gao Zhao, Wei Cao. Corosolic acid inhibits the proliferation of glomerular mesangial cells and protects against diabetic renal damage.
Scientific reports.
2016 05; 6(?):26854. doi:
10.1038/srep26854. [PMID: 27229751] - Shi-jun Liu, Zhi-xin Liao, Zhi-shu Tang, Chun-li Cui, Hong-bo Liu, Yan-ni Liang, Yu Zhang. [Chemical Constituents from Rubus stans].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2016 May; 39(5):1045-8. doi:
. [PMID: 30133048] - Jie Yang, Yuan-Jia Hu, Bo-Yang Yu, Jin Qi. Integrating qualitative and quantitative characterization of Prunellae Spica by HPLC-QTOF/MS and HPLC-ELSD.
Chinese journal of natural medicines.
2016 May; 14(5):391-400. doi:
10.3724/sp.j.1009.2016.00391. [PMID: 27478103] - Jiyoon Cho, Lisa Tremmel, Okkyung Rho, Andrew M Camelio, Dionicio Siegel, Thomas J Slaga, John DiGiovanni. Evaluation of pentacyclic triterpenes found in Perilla frutescens for inhibition of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Oncotarget.
2015 Nov; 6(36):39292-306. doi:
10.18632/oncotarget.5751. [PMID: 26513295] - Qing Wang, Qiaomei Sun, Xiangling Ma, Zaisheng Rao, Hui Li. Probing the binding interaction of human serum albumin with three bioactive constituents of Eriobotrta japonica leaves: Spectroscopic and molecular modeling approaches.
Journal of photochemistry and photobiology. B, Biology.
2015 Jul; 148(?):268-276. doi:
10.1016/j.jphotobiol.2015.04.030. [PMID: 25985147] - Hongliang Wu, Guoliang Li, Shucheng Liu, Di Liu, Guang Chen, Na Hu, Yourui Suo, Jinmao You. Simultaneous determination of six triterpenic acids in some Chinese medicinal herbs using ultrasound-assisted dispersive liquid-liquid microextraction and high-performance liquid chromatography with fluorescence detection.
Journal of pharmaceutical and biomedical analysis.
2015 Mar; 107(?):98-107. doi:
10.1016/j.jpba.2014.10.031. [PMID: 25569287] - Bidya Dhar Sahu, Madhusudana Kuncha, Shyam Sunder Rachamalla, Ramakrishna Sistla. Lagerstroemia speciosa L. attenuates apoptosis in isoproterenol-induced cardiotoxic mice by inhibiting oxidative stress: possible role of Nrf2/HO-1.
Cardiovascular toxicology.
2015 Jan; 15(1):10-22. doi:
10.1007/s12012-014-9263-1. [PMID: 24853613] - Yi Li, Jing-jing Li, Xiao-dong Wen, Rong Pan, Yi-sheng He, Jie Yang. Metabonomic analysis of the therapeutic effect of Potentilla discolor in the treatment of type 2 diabetes mellitus.
Molecular bioSystems.
2014 Nov; 10(11):2898-906. doi:
10.1039/c4mb00278d. [PMID: 25118630] - Man-Man Li, Xiao-Qin Su, Jing Sun, Yu-Fan Gu, Zheng Huang, Ke-Wu Zeng, Qian Zhang, Yun-Fang Zhao, Daneel Ferreira, Jordan K Zjawiony, Jun Li, Peng-Fei Tu. Anti-inflammatory ursane- and oleanane-type triterpenoids from Vitex negundo var. cannabifolia.
Journal of natural products.
2014 Oct; 77(10):2248-54. doi:
10.1021/np500509q. [PMID: 25245917] - K S Jayakumar, J S Sajan, R Aswati Nair, P Padmesh Pillai, S Deepu, R Padmaja, A Agarwal, A G Pandurangan. Corosolic acid content and SSR markers in Lagerstroemia speciosa (L.) Pers.: a comparative analysis among populations across the Southern Western Ghats of India.
Phytochemistry.
2014 Oct; 106(?):94-103. doi:
10.1016/j.phytochem.2014.07.004. [PMID: 25092227] - Myung-Sook Choi, Ri Ryu, Yu Ri Seo, Tae-Sook Jeong, Dong-Ha Shin, Yong Bok Park, Sang Ryong Kim, Un Ju Jung. The beneficial effect of soybean (Glycine max (L.) Merr.) leaf extracts in adults with prediabetes: a randomized placebo controlled trial.
Food & function.
2014 Jul; 5(7):1621-30. doi:
10.1039/c4fo00199k. [PMID: 24873894] - Chao Wang, Jing Yang, Ping Zhao, Qi Zhou, Zhinan Mei, Guangzhong Yang, Xinzhou Yang, Yunjiang Feng. Chemical constituents from Eucalyptus citriodora Hook leaves and their glucose transporter 4 translocation activities.
Bioorganic & medicinal chemistry letters.
2014 Jul; 24(14):3096-9. doi:
10.1016/j.bmcl.2014.05.014. [PMID: 24894556] - Baohong Li, Jindong Wu, Xianglu Li. Quantitative determination of corosolic acid in rat plasma by LC-MS/MS-ESI: application to a pharmacokinetic study.
Pakistan journal of pharmaceutical sciences.
2014 May; 27(3):511-6. doi:
NULL. [PMID: 24811810] - Jing-jing Li, Yi Li, Min Bai, Jing-fu Tan, Qiang Wang, Jie Yang. Simultaneous determination of corosolic acid and euscaphic acid in the plasma of normal and diabetic rat after oral administration of extract of Potentilla discolor Bunge by high-performance liquid chromatography/electrospray ionization mass spectrometry.
Biomedical chromatography : BMC.
2014 May; 28(5):717-24. doi:
10.1002/bmc.3098. [PMID: 24311372] - Jiao Chen, Chun-Lin Fan, Ying Wang, Wen-Cai Ye. A new triterpenoid glycoside from Vitex negundo.
Chinese journal of natural medicines.
2014 Mar; 12(3):218-21. doi:
10.1016/s1875-5364(14)60036-4. [PMID: 24702809] - Xi Liu, Liancai Zhu, Jun Tan, Xuemei Zhou, Ling Xiao, Xian Yang, Bochu Wang. Glucosidase inhibitory activity and antioxidant activity of flavonoid compound and triterpenoid compound from Agrimonia Pilosa Ledeb.
BMC complementary and alternative medicine.
2014 Jan; 14(?):12. doi:
10.1186/1472-6882-14-12. [PMID: 24410924] - Bin Li, Xianjun Meng, Lijie Zhu, Xinyao Jiao, Jiachen Zhang. Application of high-speed counter-current chromatography for isolation of triterpenes from Schisandra Chinensis (Turcz.) Baill and induction apoptosis mechanism of HSC-T6.
Bio-medical materials and engineering.
2014; 24(1):969-77. doi:
10.3233/bme-130892. [PMID: 24211986] - Kishor Mazumder, Katsunori Tanaka, Koichi Fukase. Cytotoxic activity of ursolic acid derivatives obtained by isolation and oxidative derivatization.
Molecules (Basel, Switzerland).
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