Chemical Formula: C8H8O5

Chemical Formula C8H8O5

Found 54 metabolite its formula value is C8H8O5

3-methylgallic acid

3,4-Dihydroxy-5-methoxybenzoic acid, AldrichCPR

C8H8O5 (184.0371718)


3-O-methylgallic acid is a member of the class of benzoic acids that is gallic acid in which the phenolic hydroxy group at position 3 is converted into the corresponding methyl ether. It is a member of catechols and a member of benzoic acids. It is functionally related to a gallic acid. It is a conjugate acid of a 3-O-methylgallate. 3,4-Dihydroxy-5-methoxybenzoic acid is a natural product found in Aloe africana, Macaranga tanarius, and other organisms with data available. 3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects[1][2]. 3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects[1][2].

   

3,4-Dihydroxymandelic acid

2-(3,4-dihydroxyphenyl)-2-hydroxyacetic acid

C8H8O5 (184.0371718)


3,4-Dihydroxymandelic acid, also known as DOMA or 3,4-dihydroxyphenylglycolate, belongs to the class of organic compounds known as catechols. Catechols are compounds containing a 1,2-benzenediol moiety. 3,4-Dihydroxymandelic acid exists in all living organisms, ranging from bacteria to humans. Within humans, 3,4-dihydroxymandelic acid participates in a number of enzymatic reactions. In particular, 3,4-dihydroxymandelic acid can be biosynthesized from 3,4-dihydroxymandelaldehyde through its interaction with the enzyme aldehyde dehydrogenase, dimeric nadp-preferring. In addition, 3,4-dihydroxymandelic acid and guaiacol can be converted into vanillylmandelic acid and pyrocatechol through the action of the enzyme catechol O-methyltransferase. In humans, 3,4-dihydroxymandelic acid is involved in the metabolic disorder called tyrosinemia type I. Outside of the human body, 3,4-Dihydroxymandelic acid has been detected, but not quantified in several different foods, such as yellow wax beans, soy beans, pomegranates, cucurbita (gourd), and daikon radish. 3,4-dihydroxymandelic acid, also known as 3,4-dihydroxyphenylglycolate or (3,4-dihydroxyphenyl)(hydroxy)acetic acid, is a member of the class of compounds known as catechols. Catechols are compounds containing a 1,2-benzenediol moiety. 3,4-dihydroxymandelic acid is soluble (in water) and a moderately acidic compound (based on its pKa). 3,4-dihydroxymandelic acid can be found in a number of food items such as lime, pitanga, sapodilla, and persimmon, which makes 3,4-dihydroxymandelic acid a potential biomarker for the consumption of these food products. 3,4-dihydroxymandelic acid can be found primarily in blood and urine, as well as in human nerve cells tissue. In humans, 3,4-dihydroxymandelic acid is involved in a couple of metabolic pathways, which include disulfiram action pathway and tyrosine metabolism. 3,4-dihydroxymandelic acid is also involved in several metabolic disorders, some of which include hawkinsinuria, alkaptonuria, dopamine beta-hydroxylase deficiency, and tyrosinemia, transient, of the newborn. D000890 - Anti-Infective Agents > D000892 - Anti-Infective Agents, Urinary > D008333 - Mandelic Acids Acquisition and generation of the data is financially supported in part by CREST/JST. KEIO_ID D066 3,4-Dihydroxymandelic acid is a metabolite of norepinephrine.

   

Methyl_gallate

InChI=1/C8H8O5/c1-13-8(12)4-2-5(9)7(11)6(10)3-4/h2-3,9-11H,1H

C8H8O5 (184.0371718)


Methyl 3,4,5-trihydroxybenzoate is a gallate ester obtained by the formal condensation of gallic acid with methanol. It exhibits anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory properties. It has a role as a plant metabolite, an anti-inflammatory agent and an antioxidant. Methyl gallate is a natural product found in Euphorbia teheranica, Euphorbia hyssopifolia, and other organisms with data available. See also: Paeonia lactiflora root (part of). A gallate ester obtained by the formal condensation of gallic acid with methanol. It exhibits anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory properties. Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities. Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities.

   

Methyl 2,4,6-trihydroxybenzoate

Benzoic acid, 2,4,6-trihydroxy-, methyl ester

C8H8O5 (184.0371718)


Methyl 2,4,6-trihydroxybenzoate is found in onion-family vegetables. Methyl 2,4,6-trihydroxybenzoate is isolated from onion ski Methyl 2,4,6-trihydroxybenzoate is a metabolite of 2,4,6-trihydroxybenzoate and exhibits properties as an antioxidant, lipid lowering and anticancer activities[1].

   

2,3-Dihydroxy-4-methoxybenzoic acid

2,3-Dihydroxy-4-methoxybenzoic acid

C8H8O5 (184.0371718)


   

4-O-Methylgallic acid

3,5-Dihydroxy-4-methoxy-benzoic acid

C8H8O5 (184.0371718)


4-O-Methyl gallic acid (4-OMGA) has first been identified as a major methyl derivative of gallic acid in human plasma and urine. More recently, 4-O-methyl gallic acid (4-OMGA) has been found in urine during regular black tea ingestion and in plasma after moderate red wine consumption. PMID: 15527792. 4-O-methylgallic acid (4-OMGA), a major metabolite of gallic acid abundant in red wine. 4-OMGA inhibited the expression of intercellular adhesion molecule-1(ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs) stimulated with tumor necrosis factor-alpha (TNF-alpha), resulting in the suppression of leukocyte adhesion to HUVECs (PMID: 17027748). 4-O-Methyl gallic acid has been found to be a metabolite of Beauveria and Pantoea (PMID: 17111140) (https://www.researchgate.net/publication/275561863_Microbial_Degradation_of_Bergenin_a_Phenolic_C-Glucoside). 4-O-Methyl gallic acid (4-OMGA) has first been identified as a major methyl derivative of gallic acid in human plasma and urine. More recently, 4-O-methyl gallic acid (4-OMGA) has been found in urine during regular black tea ingestion and in plasma after moderate red wine consumption. PMID: 15527792

   

2-(3,4,5-trihydroxyphenyl)acetic Acid

2-(3,4,5-trihydroxyphenyl)acetic Acid

C8H8O5 (184.0371718)


   

Methyl gallate

345-Trihydroxy-benzoic acid methyl ester

C8H8O5 (184.0371718)


Methyl gallate, also known as methyl 3 or methyl galloic acid, is a member of the class of compounds known as galloyl esters. Galloyl esters are organic compounds that contain an ester derivative of 3,4,5-trihydroxybenzoic acid. Methyl gallate is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Methyl gallate can be found in peach and pomegranate, which makes methyl gallate a potential biomarker for the consumption of these food products. Methyl gallate is a phenolic compound. It is the methyl ester of gallic acid . Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities. Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities.

   

Methyl gallate

methyl 3,4,5-trihydroxybenzoate

C8H8O5 (184.0371718)


Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities. Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities.

   
   

3-Methoxygallic acid

3,4-Dihydroxy-5-methoxybenzoic acid

C8H8O5 (184.0371718)


3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects[1][2]. 3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects[1][2].

   

Leiocarpic acid

Leiocarpic acid

C8H8O5 (184.0371718)


   

2-hydroxy-1-(2,4,6-trihydroxyphenyl)ethanone

2-hydroxy-1-(2,4,6-trihydroxyphenyl)ethanone

C8H8O5 (184.0371718)


   
   

5-ACETOXYMETHYL-2-FURANCARBOXYLIC ACID

5-ACETOXYMETHYL-2-FURANCARBOXYLIC ACID

C8H8O5 (184.0371718)


   

3,6-Dihydroxy-2-methoxybenzoic acid

3,6-Dihydroxy-2-methoxybenzoic acid

C8H8O5 (184.0371718)


   

methyl 2,3,4-trihydroxybenzoate

methyl 2,3,4-trihydroxybenzoate

C8H8O5 (184.0371718)


   

2,5-Furandiacetic acid

2,5-Furandiacetic acid

C8H8O5 (184.0371718)


   

(5-hydroxy-2-oxo-2H-pyran-4-yl)methyl acetate

(5-hydroxy-2-oxo-2H-pyran-4-yl)methyl acetate

C8H8O5 (184.0371718)


   
   

6-Hydroxymethyl-2,3,4-trihydroxybenzaldehyde

6-Hydroxymethyl-2,3,4-trihydroxybenzaldehyde

C8H8O5 (184.0371718)


   

Fumigatin-oxide

Fumigatin-oxide

C8H8O5 (184.0371718)


   

2,3,5-Trihydroxyphenylacetic acid

2,3,5-Trihydroxyphenylacetic acid

C8H8O5 (184.0371718)


   

methyl (2,3,4,6-tetrahydroxyphenyl) ketone

methyl (2,3,4,6-tetrahydroxyphenyl) ketone

C8H8O5 (184.0371718)


   

2-oxo-3-carboxy-4,5-cyclopropylhex-5-enoate

2-oxo-3-carboxy-4,5-cyclopropylhex-5-enoate

C8H8O5 (184.0371718)


   

3,4-Dihydroxymandelic acid

dl-3,4-dihydroxymandelic acid

C8H8O5 (184.0371718)


D000890 - Anti-Infective Agents > D000892 - Anti-Infective Agents, Urinary > D008333 - Mandelic Acids A catechol that is the 3,4-dihydroxy derivative of mandelic acid; a metabolite of L-dopa. 3,4-Dihydroxymandelic acid is a metabolite of norepinephrine.

   

Methylgallate

Methylgallate

C8H8O5 (184.0371718)


   

Dihydroxymandelic acid

3,4-Dihydroxymandelic acid

C8H8O5 (184.0371718)


3,4-Dihydroxymandelic acid is a metabolite of norepinephrine.

   

Methyl 2,4,6-trihydroxybenzoate

Benzoic acid, 2,4,6-trihydroxy-, methyl ester

C8H8O5 (184.0371718)


Methyl 2,4,6-trihydroxybenzoate is a metabolite of 2,4,6-trihydroxybenzoate and exhibits properties as an antioxidant, lipid lowering and anticancer activities[1].

   

ethenyl acetate,furan-2,5-dione

ethenyl acetate,furan-2,5-dione

C8H8O5 (184.0371718)


   

Dimethyl furan-2,5-dicarboxylate

Dimethyl furan-2,5-dicarboxylate

C8H8O5 (184.0371718)


   

2,5-Dihydro-4-methyl-2,5-dioxo-3-furanpropanoic Acid

2,5-Dihydro-4-methyl-2,5-dioxo-3-furanpropanoic Acid

C8H8O5 (184.0371718)


   

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic acid

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic acid

C8H8O5 (184.0371718)


   

5-HYDROXY-4-OXO-4H-PYRAN-2-CARBOXYLIC ACID ETHYL ESTER

5-HYDROXY-4-OXO-4H-PYRAN-2-CARBOXYLIC ACID ETHYL ESTER

C8H8O5 (184.0371718)


   

dimethyl 3,4-furandicarboxylate

dimethyl 3,4-furandicarboxylate

C8H8O5 (184.0371718)


   

3,4-Dihydroxymandelic acid, (R)-

3,4-Dihydroxymandelic acid, (R)-

C8H8O5 (184.0371718)


   

5-(Ethoxycarbonyl)furan-2-carboxylic acid

5-(Ethoxycarbonyl)furan-2-carboxylic acid

C8H8O5 (184.0371718)


   

99-24-1

InChI=1\C8H8O5\c1-13-8(12)4-2-5(9)7(11)6(10)3-4\h2-3,9-11H,1H

C8H8O5 (184.0371718)


Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities. Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities.

   

4319-02-2

Benzoic acid, 3,5-dihydroxy-4-methoxy-

C8H8O5 (184.0371718)


   

3,4-Dihydroxy-5-methoxybenzoic acid

3,4-Dihydroxy-5-methoxybenzoic acid

C8H8O5 (184.0371718)


Present in hydrolysed soy protein and oak aged wines and brandies. 3,4-Dihydroxy-5-methoxybenzoic acid is found in alcoholic beverages and pulses. 3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects[1][2]. 3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects[1][2].

   
   

2,4,5-Trihydroxyphenylacetic acid

2,4,5-Trihydroxyphenylacetic acid

C8H8O5 (184.0371718)


A benzenetriol that is phenylacetic acid carrying three hydroxy substituents at positions 2, 4 and 5.

   

(2S)-2-(3,4-dihydroxyphenyl)-2-hydroxyacetic acid

(2S)-2-(3,4-dihydroxyphenyl)-2-hydroxyacetic acid

C8H8O5 (184.0371718)


   

2-(2,4-Dihydroxyphenyl)-2-hydroxyacetic acid

2-(2,4-Dihydroxyphenyl)-2-hydroxyacetic acid

C8H8O5 (184.0371718)


   

3,5-dihydroxy-p-anisic acid

3,5-Dihydroxy-4-methoxybenzoic acid

C8H8O5 (184.0371718)


   

3,4,5-Trihydroxyphenylacetate

3,4,5-Trihydroxyphenylacetate

C8H8O5 (184.0371718)


   

O-Methylgallic acid

O-Methylgallic acid

C8H8O5 (184.0371718)


   

2,6-dihydroxy-3-methoxy-5-methylcyclohexa-2,5-diene-1,4-dione

2,6-dihydroxy-3-methoxy-5-methylcyclohexa-2,5-diene-1,4-dione

C8H8O5 (184.0371718)


   

5-[(acetyloxy)methyl]furan-2-carboxylic acid

5-[(acetyloxy)methyl]furan-2-carboxylic acid

C8H8O5 (184.0371718)


   

5-[(acetyloxy)methyl]furan-3-carboxylic acid

5-[(acetyloxy)methyl]furan-3-carboxylic acid

C8H8O5 (184.0371718)


   

(1r,6s)-3-hydroxy-4-methoxy-1-methyl-7-oxabicyclo[4.1.0]hept-3-ene-2,5-dione

(1r,6s)-3-hydroxy-4-methoxy-1-methyl-7-oxabicyclo[4.1.0]hept-3-ene-2,5-dione

C8H8O5 (184.0371718)


   

3,4,5-trihydroxy-2-methylbenzoic acid

3,4,5-trihydroxy-2-methylbenzoic acid

C8H8O5 (184.0371718)


   

3-hydroxy-4-methoxy-1-methyl-7-oxabicyclo[4.1.0]hept-3-ene-2,5-dione

3-hydroxy-4-methoxy-1-methyl-7-oxabicyclo[4.1.0]hept-3-ene-2,5-dione

C8H8O5 (184.0371718)


   

2,3,4-trihydroxy-6-(hydroxymethyl)benzaldehyde

2,3,4-trihydroxy-6-(hydroxymethyl)benzaldehyde

C8H8O5 (184.0371718)