Mangiferin (BioDeep_00000230176)

Secondary id: BioDeep_00000003897, BioDeep_00000018968, BioDeep_00000863242

natural product PANOMIX_OTCML-2023

代谢物信息卡片

1,3,6,7-Tetrahydroxy-2-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-9H-xanthen-9-one

化学式: C19H18O11 (422.0849078)
中文名称: 芒果苷, 杧果甙, 芒果甙
谱图信息: 最多检出来源 Viridiplantae(plant) 5.56%

分子结构信息

SMILES: c1(c(c(c2c(c1)oc1c(c2=O)cc(c(c1)O)O)O)[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O
InChI: InChI=1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1

描述信息

Mangiferin is a C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position. It has a role as a hypoglycemic agent, an antioxidant, an anti-inflammatory agent and a plant metabolite. It is a C-glycosyl compound and a member of xanthones. It is functionally related to a xanthone. It is a conjugate acid of a mangiferin(1-).
Mangiferin is a natural product found in Salacia chinensis, Smilax bracteata, and other organisms with data available.
See also: Mangifera indica bark (part of).
A C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position.
Origin: Plant
Mangiferin is a Nrf2 activator. Mangiferin suppresses nuclear translocation of the NF-κB subunits p65 and p50. Mangiferin exhibits antioxidant, antidiabetic, antihyperuricemic, antiviral, anticancer and antiinflammatory activities[1][2][3].
Mangiferin is a Nrf2 activator. Mangiferin suppresses nuclear translocation of the NF-κB subunits p65 and p50. Mangiferin exhibits antioxidant, antidiabetic, antihyperuricemic, antiviral, anticancer and antiinflammatory activities[1][2][3].

同义名列表

42 个代谢物同义名

1,3,6,7-Tetrahydroxy-2-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-9H-xanthen-9-one; 1,3,6,7-tetrahydroxy-2-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]xanthen-9-one; 1,3,6,7-tetrahydroxy-2-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]xanthen-9-one; (1S)-1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-2-yl)-D-glucitol; 9H-Xanthen-9-one, 2-beta-D-glucopyranosyl-1,3,6,7-tetrahydroxy- (9CI); 9H-Xanthen-9-one, 2-.beta.-D-glucopyranosyl-1,3,6,7-tetrahydroxy-; 9H-xanthen-9-one, 2-beta-D-glucopyranosyl-1,3,6,7-tetrahydroxy-; 2-beta-D-glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one; 9H-Xanthen-9-one, 2-b-D-glucopyranosyl-1,3,6,7-tetrahydroxy-; Mangiferin, European Pharmacopoeia (EP) Reference Standard; 2-beta-D-Glucopyranosyl-1,3,6,7-tetrahydroxy xanthone; c2-beta-d-glucopyranosyl-1,3,6,7-tetrahydroxyxanthone; mangiferin from mangifera indica leaves; Mangiferin, analytical standard; Mangiferin Mangifera indica; AEDDIBAIWPIIBD-ZJKJAXBQSA-N; Xanthone-c-glucoside; MANGIFERIN [WHO-DD]; MANGIFERIN (USP-RS); MANGIFERIN [USP-RS]; MANGIFERIN [INCI]; BCBcMAP01_000240; UNII-1M84LD0UMD; Mangiferin,(S); Mannipherin; Chedisaride; Euxanthogen; SMP1_000290; Hedysaride; Alpizarine; Mangiferol; 1M84LD0UMD; Mangiferin; Chinoinin; Hedysarid; Chinomine; alpizarin; Chinomin; Aphloiol; chinonin; Shamimin; HZI

数据库引用编号

39 个数据库交叉引用编号

ChEBI: CHEBI:6682
KEGG: C10077
PubChem: 5281647
ChEMBL: CHEMBL464825
Wikipedia: Mangiferin
MeSH: mangiferin
ChemIDplus: 0004773960
KNApSAcK: C00002962
chemspider: 4444966
CAS: 4773-96-0
MoNA: CCMSLIB00000078863
MoNA: CCMSLIB00000078892
MoNA: PM006001
MoNA: VF-NPL-QTOF008415
MoNA: VF-NPL-QTOF008414
MoNA: VF-NPL-QTOF008413
MoNA: VF-NPL-QTOF008412
MoNA: VF-NPL-QTOF008411
MoNA: VF-NPL-QTOF008410
MoNA: VF-NPL-QTOF008409
MoNA: VF-NPL-QTOF008408
MoNA: NGA00860
MoNA: NGA00859
MoNA: NGA00858
MoNA: NGA00857
MoNA: CB000342
MoNA: VF-NPL-LTQ006688
MoNA: VF-NPL-LTQ006686
MoNA: VF-NPL-LTQ006685
MoNA: TY000147
medchemexpress: HY-N0290
PMhub: MS000102476
PMhub: MS000059958
MetaboLights: MTBLC6682
PubChem: 12263
PDB-CCD: HZI
3DMET: B03519
NIKKAJI: J15.735J
RefMet: Mangiferin

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

278 个相关的物种来源信息

33090 知母: -
58832 Didymoglossum krausii: 10.1002/J.1537-2197.1996.TB13914.X
221328 Trichomanes polypodioides: 10.1002/J.1537-2197.1996.TB13914.X
282553 Hypericum sampsonii:
1009589 Salacia chinensis:
1045134 Smilax bracteata: 10.1016/J.PHYTOCHEM.2008.01.002
122946 Iris unguicularis: 10.1515/ZNC-1985-5-608
354415 Rigidella: 10.1515/ZNC-1985-5-608
93022 Moraea setifolia: 10.1515/ZNC-1985-5-608
152723 Gelasine elongata: 10.1515/ZNC-1985-5-608
1265918 Iris suaveolens: 10.1515/ZNC-1985-5-608
656932 Moraea australis: 10.1515/ZNC-1985-5-608
501379 Tigridia alpestris: 10.1515/ZNC-1985-5-608
501383 Tigridia orthantha: 10.1515/ZNC-1985-5-608
995819 Iris pumila: 10.1515/ZNC-1985-5-608
1210469 Eleutherine bulbosa: 10.1515/ZNC-1985-5-608
155109 Cyclopia subternata: 10.1021/JF040097Z
337839 Cyclopia falcata: 10.1021/JF040097Z
29780 Mangifera indica:
384038 Cyclopia intermedia:
2065894 Gentianopsis virgata: 10.1016/0305-1978(82)90006-0
866904 Gentianopsis lanceolata: 10.1016/0305-1978(82)90006-0
866906 Gentianopsis thermalis: 10.1016/0305-1978(82)90006-0
50802 Gentianopsis paludosa: 10.1016/0305-1978(82)90006-0
38851 Gentiana lutea:
50801 Gentianopsis grandis: 10.1016/0305-1978(82)90006-0
208027 Gentianella serotina: 10.1016/0305-1978(82)90006-0
84894 Gentianopsis crinita: 10.1016/0305-1978(82)90006-0
669700 Gentianopsis detonsa: 10.1016/0305-1978(82)90006-0
49940 Gentianella campestris:
1085736 Gentiana orbicularis: 10.1016/0305-1978(82)90006-0
156522 Gentianopsis barbata: 10.1016/0305-1978(82)90006-0
49941 Gentianopsis ciliata: 10.1016/0305-1978(82)90006-0
1851450 Swertia punctata: 10.1016/S0031-9422(02)00231-5
2576744 Gentianella nitida: 10.1055/S-2006-957908
223760 Gyrinops walla: 10.1021/NP50040A043
65561 Hypericum perforatum:
34205 Iris germanica:
353946 Fridericia patellifera: 10.1021/NP800406Q
1608368 Tripterospermum japonicum: 10.1248/CPB.47.962
2604127 Fridericia samydoides: 10.1021/NP030100T
1565083 Salacia reticulata:
574900 Gentiana thunbergii: 10.1055/S-2006-962408
355332 Polygala tenuifolia: 10.1016/J.BMCL.2013.08.085
198361 Canscora alata:
137888 Swertia mussotii: 10.3987/COM-11-12257
166613 Swertia calycina:
45325 Bombax ceiba:
210372 Aquilaria sinensis:
481060 Crocus gargaricus: 10.1515/ZNC-1984-1-204
1641286 Hedysarum inundatum: 10.1007/BF00630415
57576 Hedysarum alpinum: 10.1007/BF00630415
140968 Hypericum androsaemum:
626746 Hypericum humifusum:
626748 Hypericum pulchrum: 10.1055/S-2006-962050
1696186 Hypericum australe: 10.1055/S-2006-962050
673927 Hypericum hircinum: 10.1016/S0367-326X(00)00189-1
363515 Swertia souliei: 10.1016/S0367-326X(02)00011-4
1460259 Swertia corymbosa: 10.1016/S0367-326X(02)00011-4
49935 Gentiana asclepiadea: 10.1007/BF00630332
113247 Bersama abyssinica: 10.1055/S-2007-969569
282549 Hypericum olympicum: 10.1016/S0305-1978(98)00010-6
1137028 Hypericum spruneri: 10.1016/S0305-1978(98)00010-6
55963 Hypericum calycinum: 10.1016/S0305-1978(98)00010-6
212239 Hypericum patulum: 10.1016/S0305-1978(98)00010-6
1137017 Hypericum rumeliacum: 10.1016/S0305-1978(98)00010-6
1136959 Hypericum bithynicum: 10.1016/S0305-1978(98)00010-6
673922 Hypericum barbatum: 10.1016/S0305-1978(98)00010-6
673928 Hypericum hirsutum: 10.1016/S0305-1978(98)00010-6
1137008 Hypericum perfoliatum: 10.1016/S0305-1978(98)00010-6
257780 Hypericum empetrifolium: 10.1016/S0305-1978(98)00010-6
1137004 Hypericum origanifolium: 10.1016/S0305-1978(98)00010-6
1136997 Hypericum montbretii: 10.1016/S0305-1978(98)00010-6
1321348 Hypericum rochelii: 10.1016/S0305-1978(98)00010-6
282542 Hypericum japonicum: 10.1016/S0305-1978(98)00010-6
626745 Hypericum bupleuroides: 10.1016/S0305-1978(98)00010-6
1321321 Hypericum aucheri: 10.1016/S0305-1978(98)00010-6
282533 Hypericum attenuatum: 10.1016/S0305-1978(98)00010-6
269006 Hypericum maculatum: 10.1016/S0305-1978(98)00010-6
673931 Hypericum polyphyllum: 10.1016/S0305-1978(98)00010-6
1137022 Hypericum scabrum: 10.1016/S0305-1978(98)00010-6
673929 Hypericum montanum: 10.1016/S0305-1978(98)00010-6
1321328 Hypericum elegans: 10.1016/S0305-1978(98)00010-6
282558 Hypericum triquetrifolium: 10.1016/S0305-1978(98)00010-6
1321357 Hypericum thasium: 10.1016/S0305-1978(98)00010-6
1137043 Hypericum xylosteifolium: 10.1016/S0305-1978(98)00010-6
65727 Deparia petersenii: 10.1021/NP50029A025
208745 Deparia boryana: 10.1021/NP50029A025
208735 Deparia japonica: 10.1021/NP50029A025
983334 Gymnocarpium robertianum: 10.1021/NP50029A025
1133549 Cystopteris montana: 10.1021/NP50029A025
2706154 Physematium manchuriense: 10.1021/NP50029A025
623704 Gymnocarpium remotepinnatum: 10.1021/NP50029A025
872910 Woodsia glabella: 10.1021/NP50029A025
1701597 Woodsia montevidensis: 10.1021/NP50029A025
1328778 Cystopteris diaphana: 10.1021/NP50029A025
208747 Deparia henryi: 10.1021/NP50029A025
1328779 Cystopteris douglasii: 10.1021/NP50029A025
2706189 Physematium molle: 10.1021/NP50029A025
1328776 Cystopteris alpina: 10.1021/NP50029A025
32117 Gymnocarpium oyamense: 10.1021/NP50029A025
872508 Cystopteris sudetica: 10.1021/NP50029A025
86685 Athyrium atkinsonii: 10.1021/NP50029A025
86705 Acystopteris japonica: 10.1021/NP50029A025
757437 Physematium plummerae: 10.1021/NP50029A025
1303118 Woodsia alpina: 10.1021/NP50029A025
1498956 Woodsia scopulina: 10.1021/NP50029A025
872333 Acystopteris tenuisecta: 10.1021/NP50029A025
1111059 Cystopteris moupinensis: 10.1021/NP50029A025
32116 Gymnocarpium dryopteris: 10.1021/NP50029A025
29611 Woodsia obtusa: 10.1021/NP50029A025
2706187 Physematium elongatum: 10.1021/NP50029A025
32112 Cystopteris fragilis:
872911 Woodsia ilvensis: 10.1021/NP50029A025
32120 Woodsia polystichoides: 10.1021/NP50029A025
1701598 Woodsia rosthorniana: 10.1021/NP50029A025
18795 Delairea odorata: 10.1016/0031-9422(96)00154-9
59045 Anemarrhena asphodeloides:
58944 Iris domestica: 10.1271/BBB1961.46.2595
34213 Iris ensata: 10.1007/BF00563849
1960946 Hedysarum denticulatum: 10.1007/BF00563966
243998 Asplenium montanum: 10.1016/S0031-9422(00)97205-4
2831648 Swertia kouitchensis: 10.1021/NP400082G
2487050 Davallia sinensis: 10.1016/S0031-9422(99)00190-9
194872 Davallia solida: 10.1016/S0031-9422(99)00190-9
449851 Hymenophyllum nephrophyllum: 10.1248/CPB.43.461
137887 Swertia chirayita: 10.1016/S0040-4039(00)95355-3
995810 Iris nigricans: 10.1016/0031-9422(94)00641-6
207932 Iris missouriensis: 10.1021/NP50044A024
151834 Hiptage benghalensis: 10.1002/JPS.2600570631
155107 Cyclopia maculata: 10.1007/S00217-002-0644-5
70073 Cyclopia genistoides: 10.1007/S00217-002-0644-5
337842 Cyclopia sessiliflora: 10.1007/S00217-002-0644-5
50785 Swertia franchetiana: 10.1016/J.BSE.2004.02.008
148628 Swertia cordata: 10.1021/NP50103A019
4011 Anacardiaceae: 10.1038/SREP42683
49943 Gentiana cruciata: 10.1016/S0031-9422(00)88887-1
58832 Didymoglossum krausii: 10.1002/J.1537-2197.1996.TB13914.X
221328 Trichomanes polypodioides: 10.1002/J.1537-2197.1996.TB13914.X
282553 Hypericum sampsonii:
1009589 Salacia chinensis:
1045134 Smilax bracteata: 10.1016/J.PHYTOCHEM.2008.01.002
122946 Iris unguicularis: 10.1515/ZNC-1985-5-608
354415 Rigidella: 10.1515/ZNC-1985-5-608
93022 Moraea setifolia: 10.1515/ZNC-1985-5-608
152723 Gelasine elongata: 10.1515/ZNC-1985-5-608
1265918 Iris suaveolens: 10.1515/ZNC-1985-5-608
656932 Moraea australis: 10.1515/ZNC-1985-5-608
501379 Tigridia alpestris: 10.1515/ZNC-1985-5-608
501383 Tigridia orthantha: 10.1515/ZNC-1985-5-608
995819 Iris pumila: 10.1515/ZNC-1985-5-608
1210469 Eleutherine bulbosa: 10.1515/ZNC-1985-5-608
155109 Cyclopia subternata: 10.1021/JF040097Z
337839 Cyclopia falcata: 10.1021/JF040097Z
29780 Mangifera indica:
384038 Cyclopia intermedia:
2065894 Gentianopsis virgata: 10.1016/0305-1978(82)90006-0
866904 Gentianopsis lanceolata: 10.1016/0305-1978(82)90006-0
866906 Gentianopsis thermalis: 10.1016/0305-1978(82)90006-0
50802 Gentianopsis paludosa: 10.1016/0305-1978(82)90006-0
38851 Gentiana lutea:
50801 Gentianopsis grandis: 10.1016/0305-1978(82)90006-0
208027 Gentianella serotina: 10.1016/0305-1978(82)90006-0
84894 Gentianopsis crinita: 10.1016/0305-1978(82)90006-0
669700 Gentianopsis detonsa: 10.1016/0305-1978(82)90006-0
49940 Gentianella campestris:
1085736 Gentiana orbicularis: 10.1016/0305-1978(82)90006-0
156522 Gentianopsis barbata: 10.1016/0305-1978(82)90006-0
49941 Gentianopsis ciliata: 10.1016/0305-1978(82)90006-0
1851450 Swertia punctata: 10.1016/S0031-9422(02)00231-5
2576744 Gentianella nitida: 10.1055/S-2006-957908
223760 Gyrinops walla: 10.1021/NP50040A043
65561 Hypericum perforatum:
34205 Iris germanica:
353946 Fridericia patellifera: 10.1021/NP800406Q
1608368 Tripterospermum japonicum: 10.1248/CPB.47.962
2604127 Fridericia samydoides: 10.1021/NP030100T
1565083 Salacia reticulata:
574900 Gentiana thunbergii: 10.1055/S-2006-962408
355332 Polygala tenuifolia: 10.1016/J.BMCL.2013.08.085
198361 Canscora alata:
137888 Swertia mussotii: 10.3987/COM-11-12257
166613 Swertia calycina:
45325 Bombax ceiba:
210372 Aquilaria sinensis:
481060 Crocus gargaricus: 10.1515/ZNC-1984-1-204
1641286 Hedysarum inundatum: 10.1007/BF00630415
57576 Hedysarum alpinum: 10.1007/BF00630415
140968 Hypericum androsaemum:
626746 Hypericum humifusum:
626748 Hypericum pulchrum: 10.1055/S-2006-962050
1696186 Hypericum australe: 10.1055/S-2006-962050
673927 Hypericum hircinum: 10.1016/S0367-326X(00)00189-1
363515 Swertia souliei: 10.1016/S0367-326X(02)00011-4
1460259 Swertia corymbosa: 10.1016/S0367-326X(02)00011-4
49935 Gentiana asclepiadea: 10.1007/BF00630332
113247 Bersama abyssinica: 10.1055/S-2007-969569
282549 Hypericum olympicum: 10.1016/S0305-1978(98)00010-6
1137028 Hypericum spruneri: 10.1016/S0305-1978(98)00010-6
55963 Hypericum calycinum: 10.1016/S0305-1978(98)00010-6
212239 Hypericum patulum: 10.1016/S0305-1978(98)00010-6
1137017 Hypericum rumeliacum: 10.1016/S0305-1978(98)00010-6
1136959 Hypericum bithynicum: 10.1016/S0305-1978(98)00010-6
673922 Hypericum barbatum: 10.1016/S0305-1978(98)00010-6
673928 Hypericum hirsutum: 10.1016/S0305-1978(98)00010-6
1137008 Hypericum perfoliatum: 10.1016/S0305-1978(98)00010-6
257780 Hypericum empetrifolium: 10.1016/S0305-1978(98)00010-6
1137004 Hypericum origanifolium: 10.1016/S0305-1978(98)00010-6
1136997 Hypericum montbretii: 10.1016/S0305-1978(98)00010-6
1321348 Hypericum rochelii: 10.1016/S0305-1978(98)00010-6
282542 Hypericum japonicum: 10.1016/S0305-1978(98)00010-6
626745 Hypericum bupleuroides: 10.1016/S0305-1978(98)00010-6
1321321 Hypericum aucheri: 10.1016/S0305-1978(98)00010-6
282533 Hypericum attenuatum: 10.1016/S0305-1978(98)00010-6
269006 Hypericum maculatum: 10.1016/S0305-1978(98)00010-6
673931 Hypericum polyphyllum: 10.1016/S0305-1978(98)00010-6
1137022 Hypericum scabrum: 10.1016/S0305-1978(98)00010-6
673929 Hypericum montanum: 10.1016/S0305-1978(98)00010-6
1321328 Hypericum elegans: 10.1016/S0305-1978(98)00010-6
282558 Hypericum triquetrifolium: 10.1016/S0305-1978(98)00010-6
1321357 Hypericum thasium: 10.1016/S0305-1978(98)00010-6
1137043 Hypericum xylosteifolium: 10.1016/S0305-1978(98)00010-6
65727 Deparia petersenii: 10.1021/NP50029A025
208745 Deparia boryana: 10.1021/NP50029A025
208735 Deparia japonica: 10.1021/NP50029A025
983334 Gymnocarpium robertianum: 10.1021/NP50029A025
1133549 Cystopteris montana: 10.1021/NP50029A025
2706154 Physematium manchuriense: 10.1021/NP50029A025
623704 Gymnocarpium remotepinnatum: 10.1021/NP50029A025
872910 Woodsia glabella: 10.1021/NP50029A025
1701597 Woodsia montevidensis: 10.1021/NP50029A025
1328778 Cystopteris diaphana: 10.1021/NP50029A025
208747 Deparia henryi: 10.1021/NP50029A025
1328779 Cystopteris douglasii: 10.1021/NP50029A025
2706189 Physematium molle: 10.1021/NP50029A025
1328776 Cystopteris alpina: 10.1021/NP50029A025
32117 Gymnocarpium oyamense: 10.1021/NP50029A025
872508 Cystopteris sudetica: 10.1021/NP50029A025
86685 Athyrium atkinsonii: 10.1021/NP50029A025
86705 Acystopteris japonica: 10.1021/NP50029A025
757437 Physematium plummerae: 10.1021/NP50029A025
1303118 Woodsia alpina: 10.1021/NP50029A025
1498956 Woodsia scopulina: 10.1021/NP50029A025
872333 Acystopteris tenuisecta: 10.1021/NP50029A025
1111059 Cystopteris moupinensis: 10.1021/NP50029A025
32116 Gymnocarpium dryopteris: 10.1021/NP50029A025
29611 Woodsia obtusa: 10.1021/NP50029A025
2706187 Physematium elongatum: 10.1021/NP50029A025
32112 Cystopteris fragilis:
872911 Woodsia ilvensis: 10.1021/NP50029A025
32120 Woodsia polystichoides: 10.1021/NP50029A025
1701598 Woodsia rosthorniana: 10.1021/NP50029A025
18795 Delairea odorata: 10.1016/0031-9422(96)00154-9
59045 Anemarrhena asphodeloides:
58944 Iris domestica: 10.1271/BBB1961.46.2595
34213 Iris ensata: 10.1007/BF00563849
1960946 Hedysarum denticulatum: 10.1007/BF00563966
243998 Asplenium montanum: 10.1016/S0031-9422(00)97205-4
2831648 Swertia kouitchensis: 10.1021/NP400082G
2487050 Davallia sinensis: 10.1016/S0031-9422(99)00190-9
194872 Davallia solida: 10.1016/S0031-9422(99)00190-9
449851 Hymenophyllum nephrophyllum: 10.1248/CPB.43.461
137887 Swertia chirayita: 10.1016/S0040-4039(00)95355-3
995810 Iris nigricans: 10.1016/0031-9422(94)00641-6
207932 Iris missouriensis: 10.1021/NP50044A024
151834 Hiptage benghalensis: 10.1002/JPS.2600570631
155107 Cyclopia maculata: 10.1007/S00217-002-0644-5
70073 Cyclopia genistoides: 10.1007/S00217-002-0644-5
337842 Cyclopia sessiliflora: 10.1007/S00217-002-0644-5
50785 Swertia franchetiana: 10.1016/J.BSE.2004.02.008
148628 Swertia cordata: 10.1021/NP50103A019
4011 Anacardiaceae: 10.1038/SREP42683
49943 Gentiana cruciata: 10.1016/S0031-9422(00)88887-1
746523 Pyrrosia sheareri (Bak. ) Ching: -
187374 Pyrrosia lingua (Thunb.) Farwell: -
746522 Pyrrosia petiolosa (Christ) Ching: -
59045 Anemarrhena asphodeloides Bge.: -
33090 Plants: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Zhaoxia Li, Zhiliang Gao, Cong Chang, Zhuanglei Gao. Anticonvulsive Effect of Glucosyl Xanthone Mangiferin on Pentylenetetrazol (PTZ)-Induced Seizure-Provoked Mice. Applied biochemistry and biotechnology. 2024 Apr; 196(4):2161-2175. doi: 10.1007/s12010-023-04651-2. [PMID: 37486538]
He-Wei Ji, Chao-Rui Wang, Xiu-Wen Yuan, Jing Wang, Lin Wang, Qi-Long Cao, Ying-Hua Li, Yong-Nan Xu, Nam-Hyung Kim. Mangiferin improves early porcine embryonic development by reducing oxidative stress. Reproduction in domestic animals = Zuchthygiene. 2024 Apr; 59(4):e14565. doi: 10.1111/rda.14565. [PMID: 38646981]
Ying Zhao, Jian- Wu Li. Quantification of mangiferin in streptozotocin-induced diabetic rat plasma using UPLC-MS/MS: Pharmacokinetic assessment of Gentiana rhodantha extract after oral administration. Pakistan journal of pharmaceutical sciences. 2024 Mar; 37(2):291-296. doi: ". [PMID: 38767095]
Xuehui Deng, Bingfeng Lin, Fang Wang, Pingcui Xu, Nani Wang. Mangiferin attenuates osteoporosis by inhibiting osteoblastic ferroptosis through Keap1/Nrf2/SLC7A11/GPX4 pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Feb; 124(?):155282. doi: 10.1016/j.phymed.2023.155282. [PMID: 38176266]
Wanran Huang, Yanni Wang, Wei Huang. Mangiferin alleviates 6-OHDA-induced Parkinson's disease by inhibiting AKR1C3 to activate Wnt signaling pathway. Neuroscience letters. 2024 Jan; 821(?):137608. doi: 10.1016/j.neulet.2023.137608. [PMID: 38142926]
Chuihao Kong, Kaidi Wang, Lei Sun, Hongsu Zhao, Tongsheng Wang, Wuxi Zhou, Deling Wu, Fengqing Xu. Novel Carbon Dots Derived from Moutan Cortex Significantly Improve the Solubility and Bioavailability of Mangiferin. International journal of nanomedicine. 2024; 19(?):3611-3622. doi: 10.2147/ijn.s456053. [PMID: 38660022]
Gelin Xiang, Sa Guo, Nan Xing, Qinyun Du, Jing Qin, Huimin Gao, Yi Zhang, Shaohui Wang. Mangiferin, a Potential Supplement to Improve Metabolic Syndrome: Current Status and Future Opportunities. The American journal of Chinese medicine. 2024; 52(2):355-386. doi: 10.1142/s0192415x24500150. [PMID: 38533569]
Jelena Zivković, Kammala Ananth Kumar, Rapuru Rushendran, Kaliappan Ilango, Nouran M Fahmy, Heba A S El-Nashar, Mohamed El-Shazly, Shahira M Ezzat, Guiomar Melgar-Lalanne, Alejandra Romero-Montero, Sheila I Peña-Corona, Gerardo Leyva-Gomez, Javad Sharifi-Rad, Daniela Calina. Pharmacological properties of mangiferin: bioavailability, mechanisms of action and clinical perspectives. Naunyn-Schmiedeberg's archives of pharmacology. 2023 Sep; ?(?):. doi: 10.1007/s00210-023-02682-4. [PMID: 37658210]
Yanmei Zhong, Yingying Xu, Yongzhen Tan, Xuanxuan Zhang, Ruolun Wang, Danmin Chen, Zhaotao Wang, Xunlong Zhong. Lipidomics of the erythrocyte membrane and network pharmacology to explore the mechanism of mangiferin from Anemarrhenae rhizoma in treating type 2 diabetes mellitus rats. Journal of pharmaceutical and biomedical analysis. 2023 Jun; 230(?):115386. doi: 10.1016/j.jpba.2023.115386. [PMID: 37044004]
Bethanie Dean, Gemma Cooper, Maitreyi Shivkumar, Timothy J Snape. Hydroxy-xanthones as promising antiviral agents: Synthesis and biological evaluation against human coronavirus OC43. Bioorganic & medicinal chemistry letters. 2023 03; 84(?):129211. doi: 10.1016/j.bmcl.2023.129211. [PMID: 36863494]
Lijun Zhang, Chuhe Liu, Liufang Yin, Cheng Huang, Shengjie Fan. Mangiferin relieves CCl4-induced liver fibrosis in mice. Scientific reports. 2023 Mar; 13(1):4172. doi: 10.1038/s41598-023-30582-3. [PMID: 36914687]
Xiangcheng Fan, Guangyang Jiao, Tao Pang, Tao Wen, Zhiqing He, Jun Han, Feng Zhang, Wansheng Chen. Ameliorative effects of mangiferin derivative TPX on insulin resistance via PI3K/AKT and AMPK signaling pathways in human HepG2 and HL-7702 hepatocytes. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Mar; 114(?):154740. doi: 10.1016/j.phymed.2023.154740. [PMID: 36965373]
Tusheema Dutta, Tuyelee Das, Abilash Valsala Gopalakrishnan, Suchismita Chatterjee Saha, Mimosa Ghorai, Samapika Nandy, Manoj Kumar, Radha, Arabinda Ghosh, Nobendu Mukerjee, Abhijit Dey. Mangiferin: the miraculous xanthone with diverse pharmacological properties. Naunyn-Schmiedeberg's archives of pharmacology. 2023 Jan; ?(?):. doi: 10.1007/s00210-022-02373-6. [PMID: 36656353]
Chuanping Zhao, Zejiang Pu, Jian Gao, Chang Liu, Jianzhong Xing, Wenbo Lang, Jinting Chen, Chunmao Yuan, Chengyan Zhou. "Multiomics" Analyses Combined with Systems Pharmacology Reveal the Renoprotection of Mangiferin Monosodium Salt in Rats with Diabetic Nephropathy: Focus on Improvements in Renal Ferroptosis, Renal Inflammation, and Podocyte Insulin Resistance. Journal of agricultural and food chemistry. 2023 Jan; 71(1):358-381. doi: 10.1021/acs.jafc.2c05595. [PMID: 36519207]
Suhuan Mei, Manivel Perumal, Maurizio Battino, David D Kitts, Jianbo Xiao, Haile Ma, Xiumin Chen. Mangiferin: a review of dietary sources, absorption, metabolism, bioavailability, and safety. Critical reviews in food science and nutrition. 2023; 63(18):3046-3064. doi: 10.1080/10408398.2021.1983767. [PMID: 34606395]
Irengbam Rocky Mangangcha, Raj Kumar Brojen Singh, Djamel Lebeche, Shakir Ali. Xanthone glucoside 2-β-D-glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one binds to the ATP-binding pocket of glycogen synthase kinase 3β and inhibits its activity: implications in prostate cancer and associated cardiovascular disease risk. Journal of biomolecular structure & dynamics. 2022 10; 40(17):7868-7884. doi: 10.1080/07391102.2021.1902857. [PMID: 33769184]
Min Feng, Shaoqiang Wei, Shidong Zhang, Ying Yang. Anti-Inflammation and Anti-Pyroptosis Activities of Mangiferin via Suppressing NF-κB/NLRP3/GSDMD Signaling Cascades. International journal of molecular sciences. 2022 Sep; 23(17):. doi: 10.3390/ijms231710124. [PMID: 36077522]
Xia Mao, Yudong Liu, Weijie Li, Kexin Wang, Congchong Li, Qian Wang, Wenjia Chen, Zhaochen Ma, Xiaoyue Wang, Zihe Ding, Yanqiong Zhang, Na Lin. A promising drug combination of mangiferin and glycyrrhizic acid ameliorates disease severity of rheumatoid arthritis by reversing the disturbance of thermogenesis and energy metabolism. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2022 Sep; 104(?):154216. doi: 10.1016/j.phymed.2022.154216. [PMID: 35749826]
Andy Gálvez-Rodríguez, Anthuan Ferino-Pérez, Zalua Rodríguez-Riera, Idania Rodeiro Guerra, David Řeha, Babak Minofar, Ulises J Jáuregui-Haza. Explaining the interaction of mangiferin with MMP-9 and NF-ƙβ: a computational study. Journal of molecular modeling. 2022 Aug; 28(9):266. doi: 10.1007/s00894-022-05260-2. [PMID: 35987945]
Debora Santonocito, Maria Vivero-Lopez, Maria Rosaria Lauro, Cristina Torrisi, Francesco Castelli, Maria Grazia Sarpietro, Carmelo Puglia. Design of Nanotechnological Carriers for Ocular Delivery of Mangiferin: Preformulation Study. Molecules (Basel, Switzerland). 2022 Feb; 27(4):. doi: 10.3390/molecules27041328. [PMID: 35209120]
Ying Wang, Tanushree Karmakar, Nilanjan Ghosh, Souvik Basak, Nanda Gopal Sahoo. Targeting mangiferin loaded N-succinyl chitosan-alginate grafted nanoparticles against atherosclerosis - A case study against diabetes mediated hyperlipidemia in rat. Food chemistry. 2022 Feb; 370(?):131376. doi: 10.1016/j.foodchem.2021.131376. [PMID: 34662793]
Sumaya Akter, Akhi Moni, Golam Mahbub Faisal, Muhammad Ramiz Uddin, Nourin Jahan, Md Abdul Hannan, Asadur Rahman, Md Jamal Uddin. Renoprotective Effects of Mangiferin: Pharmacological Advances and Future Perspectives. International journal of environmental research and public health. 2022 02; 19(3):. doi: 10.3390/ijerph19031864. [PMID: 35162887]
Weijie Li, Kexin Wang, Yudong Liu, Hao Wu, Yan He, Congchong Li, Qian Wang, Xiaohui Su, Shikai Yan, Weiwei Su, Yanqiong Zhang, Na Lin. A Novel Drug Combination of Mangiferin and Cinnamic Acid Alleviates Rheumatoid Arthritis by Inhibiting TLR4/NFκB/NLRP3 Activation-Induced Pyroptosis. Frontiers in immunology. 2022; 13(?):912933. doi: 10.3389/fimmu.2022.912933. [PMID: 35799788]
Qi Zhou, Kezhu Hou, Zhiqiang Fu. Transferrin-Modified Mangiferin-Loaded SLNs: Preparation, Characterization, and Application in A549 Lung Cancer Cell. Drug design, development and therapy. 2022; 16(?):1767-1778. doi: 10.2147/dddt.s366531. [PMID: 35707686]
Lesslie Espinosa-Espinosa, Leticia Garduño-Siciliano, Mario Rodriguez-Canales, Luis Barbo Hernandez-Portilla, Maria Margarita Canales-Martinez, Marco Aurelio Rodriguez-Monroy. The Wound-Healing Effect of Mango Peel Extract on Incision Wounds in a Murine Model. Molecules (Basel, Switzerland). 2022 Jan; 27(1):. doi: 10.3390/molecules27010259. [PMID: 35011491]
Ohn Mar Lwin, Nelli Giribabu, Eswar Kumar Kilari, Naguib Salleh. Topical administration of mangiferin promotes healing of the wound of streptozotocin-nicotinamide-induced type-2 diabetic male rats. The Journal of dermatological treatment. 2021 Dec; 32(8):1039-1048. doi: 10.1080/09546634.2020.1721419. [PMID: 32013660]
Ran Wang, Jing Liu, Zhehuan Wang, Xiaohan Wu, Hui Guo, Xiangyue Jiao, Huiru Zhang, Caihong Qi, Xiaotian Li. Mangiferin exert protective effects on joints of adjuvant-induced arthritis rats by regulating the MAPKs/NF-κB pathway of fibroblast-like synoviocytes. International immunopharmacology. 2021 Dec; 101(Pt B):108352. doi: 10.1016/j.intimp.2021.108352. [PMID: 34836794]
Magdy M Awny, Asmaa K Al-Mokaddem, Bassam Mohamed Ali. Mangiferin mitigates di-(2-ethylhexyl) phthalate-induced testicular injury in rats by modulating oxidative stress-mediated signals, inflammatory cascades, apoptotic pathways, and steroidogenesis. Archives of biochemistry and biophysics. 2021 10; 711(?):108982. doi: 10.1016/j.abb.2021.108982. [PMID: 34400143]
Anna Hering, Jadwiga Renata Ochocka, Helena Baranska, Krzysztof Cal, Justyna Stefanowicz-Hajduk. Mangiferin and Hesperidin Transdermal Distribution and Permeability through the Skin from Solutions and Honeybush Extracts (Cyclopia sp.)-A Comparison Ex Vivo Study. Molecules (Basel, Switzerland). 2021 Oct; 26(21):. doi: 10.3390/molecules26216547. [PMID: 34770957]
Tian-Feng Lin, Jun-Na Qiu, Shuang Zhang, Yan Zhang, Yu Zhang, Meng Sun, Jin-Hua Zhang, Bin Liu, Fa-Feng Cheng, Yan-Yan Jiang. Screening out the anti-insomnia components from Prunella vulgaris L. based on plasma pharmacochemistry combined with pharmacodynamic experiments and UPLC-MS/MS analysis. Journal of ethnopharmacology. 2021 Oct; 279(?):114373. doi: 10.1016/j.jep.2021.114373. [PMID: 34181959]
Min Liu, Chengquan Wen, Shengqi Pan. Modulator effect of mangiferin on biochemical characterization in 7,12-dimethylbenz[a]anthracene induced oral cancer in experimental hamsters. Veterinary medicine and science. 2021 09; 7(5):2015-2025. doi: 10.1002/vms3.500. [PMID: 33949808]
Prabhjot Kaur, R C Gupta, Abhijit Dey, Tabarak Malik, Devendra Kumar Pandey. Optimization of harvest and extraction factors by full factorial design for the improved yield of C-glucosyl xanthone mangiferin from Swertia chirata. Scientific reports. 2021 08; 11(1):16346. doi: 10.1038/s41598-021-95663-7. [PMID: 34381094]
Tingjun Liu, Yuanjian Song, Ankang Hu. Neuroprotective mechanisms of mangiferin in neurodegenerative diseases. Drug development research. 2021 06; 82(4):494-502. doi: 10.1002/ddr.21783. [PMID: 33458836]
Salita Demeyer, Anan Athipornchai, Pariya Pabunrueang, Thanida Trakulsujaritchok. Development of mangiferin loaded chitosan-silica hybrid scaffolds: Physicochemical and bioactivity characterization. Carbohydrate polymers. 2021 Jun; 261(?):117905. doi: 10.1016/j.carbpol.2021.117905. [PMID: 33766383]
Zhi Tang, Chen-Cen Lai, Jun Luo, Yuan-Ting Ding, Qian Chen, Zhi-Zhong Guan. Mangiferin prevents the impairment of mitochondrial dynamics and an increase in oxidative stress caused by excessive fluoride in SH-SY5Y cells. Journal of biochemical and molecular toxicology. 2021 Apr; 35(4):e22705. doi: 10.1002/jbt.22705. [PMID: 33393728]
You Wu, Wei Liu, Tao Yang, Mei Li, Lingling Qin, Lili Wu, Tonghua Liu. Oral administration of mangiferin ameliorates diabetes in animal models: a meta-analysis and systematic review. Nutrition research (New York, N.Y.). 2021 03; 87(?):57-69. doi: 10.1016/j.nutres.2020.12.017. [PMID: 33601215]
Vaibhav Walia, Sushil Kumar Chaudhary, Neeraj Kumar Sethiya. Therapeutic potential of mangiferin in the treatment of various neuropsychiatric and neurodegenerative disorders. Neurochemistry international. 2021 02; 143(?):104939. doi: 10.1016/j.neuint.2020.104939. [PMID: 33346032]
Karim Naraki, Ramin Rezaee, Habibeh Mashayekhi-Sardoo, A Wallace Hayes, Gholamreza Karimi. Mangiferin offers protection against deleterious effects of pharmaceuticals, heavy metals, and environmental chemicals. Phytotherapy research : PTR. 2021 Feb; 35(2):810-822. doi: 10.1002/ptr.6864. [PMID: 32961631]
Lijun Zhang, Cheng Huang, Shengjie Fan. Mangiferin and organ fibrosis: A mini review. BioFactors (Oxford, England). 2021 Jan; 47(1):59-68. doi: 10.1002/biof.1693. [PMID: 33217771]
Zhang Yong, Wang Ruiqi, Yao Hongji, Ma Ning, Jiang Chenzuo, Zhou Yu, Xia Zhixuan, Liu Qiang, Liu Qibing, Lu Weiying, Zhang Xiaopo. Mangiferin Ameliorates HFD-Induced NAFLD through Regulation of the AMPK and NLRP3 Inflammasome Signal Pathways. Journal of immunology research. 2021; 2021(?):4084566. doi: 10.1155/2021/4084566. [PMID: 34734090]
Xin Wang, Tong Yuwen, Tian Yanqin. Mangiferin Inhibits Inflammation and Cell Proliferation, and Activates Proapoptotic Events via NF-κB Inhibition in DMBA-Induced Mammary Carcinogenesis in Rats. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 2021; 40(2):1-9. doi: 10.1615/jenvironpatholtoxicoloncol.2021036057. [PMID: 33822512]
Qiurui Li, Hua Lin, Yanfen Niu, Yan Liu, Zhenyu Wang, Liudong Song, Lihui Gao, Ling Li. Mangiferin promotes intestinal elimination of uric acid by modulating intestinal transporters. European journal of pharmacology. 2020 Dec; 888(?):173490. doi: 10.1016/j.ejphar.2020.173490. [PMID: 32827538]
Roberto O Ybañez-Julca, Daniel Asunción-Alvarez, Ivan M Quispe-Díaz, Javier Palacios, Jorge Bórquez, Mario J Simirgiotis, Shagufta Perveen, Chukwuemeka R Nwokocha, Fredi Cifuentes, Adrián Paredes. Metabolomic Profiling of Mango (Mangifera indica Linn) Leaf Extract and Its Intestinal Protective Effect and Antioxidant Activity in Different Biological Models. Molecules (Basel, Switzerland). 2020 Nov; 25(21):. doi: 10.3390/molecules25215149. [PMID: 33167456]
Eakkaluk Wongwad, Kornkanok Ingkaninan, Wudtichai Wisuitiprot, Boonchoo Sritularak, Neti Waranuch. Thermal Degradation Kinetics and pH-Rate Profiles of Iriflophenone 3,5-C-β-d-diglucoside, Iriflophenone 3-C-β-d-Glucoside and Mangiferin in Aquilaria crassna Leaf Extract. Molecules (Basel, Switzerland). 2020 Oct; 25(21):. doi: 10.3390/molecules25214898. [PMID: 33113908]
Stefana Cvetković, Branislav Nastasijević, Dragana Mitić-Ćulafić, Stefana Đukanović, Dina Tenji, Jelena Knežević-Vukčević, Biljana Nikolić. New insight into the antigenotoxic activity of Gentiana lutea extracts - Protective effect against food borne mutagens. Mutation research. Genetic toxicology and environmental mutagenesis. 2020 Oct; 858-860(?):503251. doi: 10.1016/j.mrgentox.2020.503251. [PMID: 33198932]
Yen-Sung Lin, Kun-Ling Tsai, Jia-Ni Chen, Chen-Shiou Wu. Mangiferin inhibits lipopolysaccharide-induced epithelial-mesenchymal transition (EMT) and enhances the expression of tumor suppressor gene PER1 in non-small cell lung cancer cells. Environmental toxicology. 2020 Oct; 35(10):1070-1081. doi: 10.1002/tox.22943. [PMID: 32420661]
Sushil Bhargava, Mamta B Shah. Evaluation of efficacy of Bombax ceiba extract and its major constituent, mangiferin in streptozotocin (STZ)-induced diabetic rats. Journal of complementary & integrative medicine. 2020 Sep; 18(2):311-318. doi: 10.1515/jcim-2020-0027. [PMID: 32941163]
Dong Zhang, Shasha Han, Yue Zhou, Boyang Qi, Xiaozhi Wang. Therapeutic effects of mangiferin on sepsis-associated acute lung and kidney injuries via the downregulation of vascular permeability and protection of inflammatory and oxidative damages. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2020 Sep; 152(?):105400. doi: 10.1016/j.ejps.2020.105400. [PMID: 32540472]
He Lin, Houlei Teng, Wei Wu, Yong Li, Guangfu Lv, Xiaowei Huang, Wenhao Yan, Zhe Lin. Pharmacokinetic and metabolomic analyses of Mangiferin calcium salt in rat models of type 2 diabetes and non-alcoholic fatty liver disease. BMC pharmacology & toxicology. 2020 08; 21(1):59. doi: 10.1186/s40360-020-00438-x. [PMID: 32762728]
Emma L Wightman, Philippa A Jackson, Joanne Forster, Julie Khan, Julia C Wiebe, Nigel Gericke, David O Kennedy. Acute Effects of a Polyphenol-Rich Leaf Extract of Mangifera indica L. (Zynamite) on Cognitive Function in Healthy Adults: A Double-Blind, Placebo-Controlled Crossover Study. Nutrients. 2020 Jul; 12(8):. doi: 10.3390/nu12082194. [PMID: 32717999]
Mandeep Kumar Arora, Anglina Kisku, Ashok Jangra. Mangiferin ameliorates intracerebroventricular-quinolinic acid-induced cognitive deficits, oxidative stress, and neuroinflammation in Wistar rats. Indian journal of pharmacology. 2020 Jul; 52(4):296-305. doi: 10.4103/ijp.ijp_699_19. [PMID: 33078731]
Neil Miller, Christiaan J Malherbe, Elizabeth Joubert. In vitroα-glucosidase inhibition by honeybush (Cyclopia genistoides) food ingredient extract-potential for dose reduction of acarbose through synergism. Food & function. 2020 Jul; 11(7):6476-6486. doi: 10.1039/d0fo01306d. [PMID: 32627774]
Junna Song, Yunxia Meng, Meng Wang, Lanzhu Li, Zhao Liu, Kaiyan Zheng, Lanfang Wu, Baolin Liu, Fangjie Hou, Aiying Li. Mangiferin activates Nrf2 to attenuate cardiac fibrosis via redistributing glutaminolysis-derived glutamate. Pharmacological research. 2020 07; 157(?):104845. doi: 10.1016/j.phrs.2020.104845. [PMID: 32353588]
Vidhushini Sekar, Sugumar Mani, R Malarvizhi, R Barathidasan, Hannah R Vasanthi. Positive interaction of mangiferin with selected oral hypoglycemic drugs: a therapeutic strategy to alleviate diabetic nephropathy in experimental rats. Molecular biology reports. 2020 Jun; 47(6):4465-4475. doi: 10.1007/s11033-020-05517-0. [PMID: 32451927]
Prabhjot Kaur, R C Gupta, Abhijit Dey, Tabarak Malik, Devendra Kumar Pandey. Optimization of salicylic acid and chitosan treatment for bitter secoiridoid and xanthone glycosides production in shoot cultures of Swertia paniculata using response surface methodology and artificial neural network. BMC plant biology. 2020 May; 20(1):225. doi: 10.1186/s12870-020-02410-7. [PMID: 32429895]
Rohini Samadarsi, Debjani Dutta. Anti-oxidative effect of mangiferin-chitosan nanoparticles on oxidative stress-induced renal cells. International journal of biological macromolecules. 2020 May; 151(?):36-46. doi: 10.1016/j.ijbiomac.2020.02.112. [PMID: 32070742]
Dovilė Grauzdytė, Audrius Pukalskas, Chaker El Kalamouni, Petras Rimantas Venskutonis. Mangiferin Rich Products from Aphloia theiformis (Vahl) Benn Leaves: Extraction, Fractionation, Phytochemical Characterization, and Antioxidant Properties. Molecules (Basel, Switzerland). 2020 Apr; 25(9):. doi: 10.3390/molecules25092081. [PMID: 32365681]
Agnieszka Piwowar, Nina Rembiałkowska, Anna Rorbach-Dolata, Arnold Garbiec, Sylwester Ślusarczyk, Agnieszka Dobosz, Anna Długosz, Zofia Marchewka, Adam Matkowski, Jolanta Saczko. Anemarrhenae asphodeloides rhizoma Extract Enriched in Mangiferin Protects PC12 Cells against a Neurotoxic Agent-3-Nitropropionic Acid. International journal of molecular sciences. 2020 Apr; 21(7):. doi: 10.3390/ijms21072510. [PMID: 32260390]
Daniele Zendrini Rechenchoski, Karoline Fontana Agostinho, Ligia Carla Faccin-Galhardi, Audrey Alesandra Stinghen Garcia Lonni, João Vinícius Honório da Silva, Fábio Goulart de Andrade, Arcelina Pacheco Cunha, Nágila Maria Pontes Silva Ricardo, Carlos Nozawa, Rosa Elisa Carvalho Linhares. Mangiferin: A promising natural xanthone from Mangifera indica for the control of acyclovir - resistant herpes simplex virus 1 infection. Bioorganic & medicinal chemistry. 2020 02; 28(4):115304. doi: 10.1016/j.bmc.2020.115304. [PMID: 31956052]
Jing Huang, Lili Zheng, Fang Wang, Yuan Su, Hongfang Kong, Hong Xin. Mangiferin ameliorates placental oxidative stress and activates PI3K/Akt/mTOR pathway in mouse model of preeclampsia. Archives of pharmacal research. 2020 Feb; 43(2):233-241. doi: 10.1007/s12272-020-01220-7. [PMID: 31989480]
René Delgado-Hernández, Ivones Hernández-Balmaseda, Idania Rodeiro-Guerra, Julio Cesar Rodriguez Gonzalez, Olivier De Wever, Emilie Logie, Ken Declerck, Claudina Pérez-Novo, Wim Vanden Berghe. Anti-angiogenic effects of mangiferin and mechanism of action in metastatic melanoma. Melanoma research. 2020 02; 30(1):39-51. doi: 10.1097/cmr.0000000000000647. [PMID: 31651714]
Yanyan Song, Wei Liu, Ke Tang, Junting Zang, Dong Li, Hang Gao. Mangiferin Alleviates Renal Interstitial Fibrosis in Streptozotocin-Induced Diabetic Mice through Regulating the PTEN/PI3K/Akt Signaling Pathway. Journal of diabetes research. 2020; 2020(?):9481720. doi: 10.1155/2020/9481720. [PMID: 32076626]
Sonali Aswal, Ankit Kumar, Ashutosh Chauhan, Ruchi Badoni Semwal, Abhimanyu Kumar, Deepak Kumar Semwal. A Molecular Approach on the Protective Effects of Mangiferin Against Diabetes and Diabetes-related Complications. Current diabetes reviews. 2020; 16(7):690-698. doi: 10.2174/1573399815666191004112023. [PMID: 31584372]
Marcela Morales, Karol Zapata, Carlos A Sagaste, Alberto A Angulo, Benjamín Rojano. Optimization of the ultrasound-assisted extraction of polyphenol, mangiferin, and its antioxidant expressionin mango peel (Mangifera indica) using response surface methodology. Acta scientiarum polonorum. Technologia alimentaria. 2020 Jan; 19(1):5-14. doi: 10.17306/j.afs.0733. [PMID: 32227693]
Kun Ren, Heng Li, Hui-Fang Zhou, Yin Liang, Min Tong, Lu Chen, Xi-Long Zheng, Guo-Jun Zhao. Mangiferin promotes macrophage cholesterol efflux and protects against atherosclerosis by augmenting the expression of ABCA1 and ABCG1. Aging. 2019 12; 11(23):10992-11009. doi: 10.18632/aging.102498. [PMID: 31790366]
Diego Ballesteros-Vivas, Gerardo Álvarez-Rivera, Sandra Johanna Morantes, Andrea Del Pilar Sánchez-Camargo, Elena Ibáñez, Fabián Parada-Alfonso, Alejandro Cifuentes. An integrated approach for the valorization of mango seed kernel: Efficient extraction solvent selection, phytochemical profiling and antiproliferative activity assessment. Food research international (Ottawa, Ont.). 2019 12; 126(?):108616. doi: 10.1016/j.foodres.2019.108616. [PMID: 31732074]
Kang He, Lin-Lin Fan, Tian-Tai Wu, Jiang Du. A new xanthone glycoside from Pyrrosia sheareri. Natural product research. 2019 Oct; 33(20):2982-2987. doi: 10.1080/14786419.2018.1514398. [PMID: 30488728]
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Ralph Urbatzka, Sara Freitas, Andreia Palmeira, Tiago Almeida, João Moreira, Carlos Azevedo, Carlos Afonso, Marta Correia-da-Silva, Emilia Sousa, Madalena Pinto, Vitor Vasconcelos. Lipid reducing activity and toxicity profiles of a library of polyphenol derivatives. European journal of medicinal chemistry. 2018 May; 151(?):272-284. doi: 10.1016/j.ejmech.2018.03.036. [PMID: 29626799]
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