NCBI Taxonomy: 58949
Crocus (ncbi_taxid: 58949)
found 6 associated metabolites at genus taxonomy rank level.
Ancestor: Croceae
Child Taxonomies: Crocus tauri, Crocus boryi, Crocus malyi, Crocus mawii, Crocus nudiflorus, Crocus crewei, Crocus lycius, Crocus flavus, Crocus mysius, Crocus orphei, Crocus niveus, Crocus medius, Crocus vernus, Crocus aerius, Crocus adamii, Crocus stridii, Crocus siculus, Crocus caspius, Crocus cyprius, Crocus atticus, Crocus minimus, Crocus paschei, Crocus sativus, Crocus veneris, Crocus pumilus, Crocus sieberi, Crocus fauseri, Crocus caricus, Crocus minutus, Crocus roopiae, Crocus nubigena, Crocus weldenii, Crocus boulosii, Crocus candidus, Crocus corsicus, Crocus cvijicii, Crocus etruscus, Crocus hyemalis, Crocus coloreus, Crocus vaclavii, Crocus mathewii, Crocus olivieri, Crocus biflorus, Crocus thomasii, Crocus pallasii, Crocus goulimyi, Crocus imperati, Crocus ilvensis, Crocus pallidus, Crocus berytius, Crocus tauricus, Crocus ponticus, Crocus autranii, Crocus arizelus, Crocus isauricus, Crocus punctatus, Crocus wattiorum, Crocus gilanicus, Crocus hermoneus, Crocus kosaninii, Crocus scardicus, Crocus serotinus, Crocus caelestis, Crocus sieheanus, Crocus vallicola, Crocus herbertii, Crocus speciosus, Crocus asumaniae, Crocus neglectus, Crocus adanensis, Crocus aleppicus, Crocus calanthus, Crocus banaticus, Crocus alexandri, Crocus carpetanus, Crocus dalmaticus, Crocus danfordiae, Crocus fleischeri, Crocus gargaricus, Crocus graveolens, Crocus adamioides, Crocus korolkowii, Crocus simavensis, Crocus incognitus, Crocus ligusticus, Crocus moabiticus, Crocus nerimaniae, Crocus nevadensis, Crocus rujanensis, Crocus danubensis, Crocus versicolor, Crocus vitellinus, Crocus naqabensis, Crocus micranthus, Crocus variegatus, Crocus laevigatus, Crocus pulchellus, Crocus marasensis, Crocus munzurense, Crocus abantensis, Crocus pelitensis, Crocus alatavicus, Crocus schneideri, Crocus almehensis, Crocus sivasensis, Crocus ancyrensis, Crocus antherotes, Crocus artvinensis, Crocus melantherus, Crocus musagecitii, Crocus cancellatus, Crocus pamphylicus, Crocus chrysanthus, Crocus karduchorum, Crocus kotschyanus, Crocus leichtlinii, Crocus longiflorus, Crocus michelsonii, Crocus ochroleucus, Crocus pestalozzae, Crocus reticulatus, Crocus robertianus, Crocus scharojanii, Crocus veluchensis, Crocus macedonicus, Crocus hadriaticus, Crocus ionopharynx, Crocus kangalensis, Crocus atrospermus, Crocus abracteolus, Crocus romuleoides, Crocus taseliensis, Crocus mersinensis, Crocus antalyensis, Crocus baytopiorum, Crocus pulchricolor, unclassified Crocus, Crocus babadagensis, Crocus pelistericus, Crocus tournefortii, Crocus kofudagensis, Crocus x jessoppiae, Crocus oreocreticus, Crocus asymmetricus, Crocus neapolitanus, Crocus heuffelianus, Crocus bertiscensis, Crocus yataganensis, Crocus terzioghluii, Crocus karamanensis, Crocus tahtaliensis, Crocus leucostylosus, Crocus cambessedesii, Crocus kurdistanicus, Crocus hartmannianus, Crocus bifloriformis, Crocus multicostatus, Crocus jablanicensis, Crocus tommasinianus, Crocus albocoronatus, Crocus angustifolius, Crocus mediotauricus, Crocus pseudonubigena, Crocus kerndorffiorum, Crocus fibroannulatus, Crocus kartaldagensis, Crocus heilbronniorum, Crocus beydaglarensis, Crocus filis-maculatis, Crocus cartwrightianus, Crocus randjeloviciorum, Crocus cf. tauri GAT 7174, Crocus cf. tauri GAT 7167, Crocus cf. tauri GAT 7158, Crocus cf. crewei GAT 7465, Crocus cf. rhodensis DH-2016, Crocus cf. ancyrensis DH-2014, Crocus cf. hittiticus DH-2014, Crocus cf. variegatus DH-2014, Crocus cf. chrysanthus DH-2016, Crocus cf. cancellatus DH-2014, Crocus cf. graveolens GAT 7457, Crocus cf. chrysanthus DH-2014, Crocus cf. chrysanthus GAT 7449, Crocus cf. chrysanthus GAT 7138, Crocus cf. chrysanthus GAT 7182, Crocus cf. chrysanthus GAT 7464
Cosmosiin
Cosmosiin, also known as apigenin 7-O-glucoside or apigetrin, is a member of the class of compounds known as flavonoid-7-O-glycosides. Flavonoid-7-O-glycosides are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position. Cosmosiin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Cosmosiin can be found in a number of food items, such as common thyme, white lupine, common oregano, and orange mint. Cosmosiin can also be found in dandelion coffee and in Teucrium gnaphalodes (Wikipedia). Cosmosiin can also be found plants such as wild celery and anise. Cosmosiin has been shown to exhibit anti-platelet function (PMID: 21834233). Apigenin 7-O-beta-D-glucoside is a glycosyloxyflavone that is apigenin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as a non-steroidal anti-inflammatory drug, a metabolite and an antibacterial agent. It is a beta-D-glucoside, a dihydroxyflavone, a glycosyloxyflavone and a monosaccharide derivative. It is functionally related to an apigenin. It is a conjugate acid of an apigenin 7-O-beta-D-glucoside(1-). It is an enantiomer of an apigenin 7-O-beta-L-glucoside. Cosmosiin is a natural product found in Galeopsis tetrahit, Carex fraseriana, and other organisms with data available. See also: Chamomile (part of). Apiumetrin, also known as 7-O-beta-D-glucosyl-5,7,4-trihydroxyflavone or cosmosiin, is a member of the class of compounds known as flavonoid-7-o-glycosides. Flavonoid-7-o-glycosides are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position. Apiumetrin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Apiumetrin can be found in wild celery, which makes apiumetrin a potential biomarker for the consumption of this food product. Acquisition and generation of the data is financially supported in part by CREST/JST. Annotation level-1 Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside) exhibits significant anti-proliferative and antioxidant activity and scavenges reactive oxygen species (ROS)[1][2]. Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside) exhibits significant anti-proliferative and antioxidant activity and scavenges reactive oxygen species (ROS)[1][2].
Crocin
Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L.) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne or tranquilizer. Saffron is now used worldwide in folk medicine and is reputed to be useful in treating various human disorders such as heart and blood disorders. Stroke and heart attack are involved in reputed folkloric uses of saffron. Saffron is orally administrated as a decoction. Saffron extract exerts a protective effect on renal ischemia reperfusion induced oxidative damage in rats. Crocin suppresses tumor necrosis factor (TNF)alpha-induced apoptosis of pheochromocytoma (PC12) cells by modulating mRNA expressions of Bcl-2 family proteins, which trigger downstream signals culminating in caspase-3 activation followed by cell death. Depriving cultured PC12 cells of serum/glucose causes a rapid increase in cellular ceramide levels, followed by an increase in the risk of cell death. The accumulation of ceramide was found to depend on the activation of neutral sphingomyelinase (nSMase). Crocin prevented the activation of nSMase by enhancing the transcription of gamma-glutamylcysteinyl synthase, which contributes to a stable glutathione supply that blocks the activity of nSMase. (PMID: 17215084). Crocetin esters present in saffron stigmas and in Gardenia jasminoides Ellis fruit are the compounds responsible for their color. (PMID: 16448211). Crocin-1 is a diester that is crocetin in which both of the carboxy groups have been converted to their gentiobiosyl esters. It is one of the water-soluble yellow-red pigments of saffron and is used as a spice for flavouring and colouring food. Note that in India, the term Crocin is also used by GlaxoSmithKline as a brand-name for paracetamol. It has a role as an antioxidant, a food colouring, a plant metabolite and a histological dye. It is a diester, a disaccharide derivative and a diterpenoid. It is functionally related to a beta-D-gentiobiosyl crocetin and a gentiobiose. Crocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia. Crocin is a natural product found in Gardenia jasminoides, Calycanthus, and other organisms with data available. D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids The colouring principle of saffron Crocin (Crocin I) is a nutraceutical and the main constituent isolated from the stigmas of Crocus sativus with immense pharmacological properties as anti-inflammatory, anticancer, antidepressant and anticonvulsant[1]. Crocin (Crocin I) is a nutraceutical and the main constituent isolated from the stigmas of Crocus sativus with immense pharmacological properties as anti-inflammatory, anticancer, antidepressant and anticonvulsant[1].
cosmetin
Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside) exhibits significant anti-proliferative and antioxidant activity and scavenges reactive oxygen species (ROS)[1][2]. Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside) exhibits significant anti-proliferative and antioxidant activity and scavenges reactive oxygen species (ROS)[1][2].