Niacinamide (BioDeep_00000000186)

 

Secondary id: BioDeep_00000399877, BioDeep_00000400349, BioDeep_00000860018

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite Toxin


代谢物信息卡片


pyridine-3-carboxamide

化学式: C6H6N2O (122.0480106)
中文名称: 烟酰胺
谱图信息: 最多检出来源 Homo sapiens(blood) 0.14%

Reviewed

Last reviewed on 2024-07-01.

Cite this Page

Niacinamide. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/niacinamide (retrieved 2024-09-17) (BioDeep RN: BioDeep_00000000186). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC(=CN=C1)C(=O)N
InChI: InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

描述信息

Nicotinamide is a white powder. (NTP, 1992)
Nicotinamide is a pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor, a metabolite, a cofactor, an antioxidant, a neuroprotective agent, an EC 3.5.1.98 (histone deacetylase) inhibitor, an anti-inflammatory agent, a Sir2 inhibitor, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a mouse metabolite, a human urinary metabolite and a geroprotector. It is a vitamin B3, a pyridinecarboxamide and a pyridine alkaloid. It is functionally related to a nicotinic acid.
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Niacinamide is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Nicotinamide is a natural product found in Mus musculus, Euonymus grandiflorus, and other organisms with data available.
Niacinamide is the active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.
Nicotinamide is a uremic toxin. Uremic toxins can be subdivided into three major groups based upon their chemical and physical characteristics: 1) small, water-soluble, non-protein-bound compounds, such as urea; 2) small, lipid-soluble and/or protein-bound compounds, such as the phenols and 3) larger so-called middle-molecules, such as beta2-microglobulin. Chronic exposure of uremic toxins can lead to a number of conditions including renal damage, chronic kidney disease and cardiovascular disease. Niacinamide or vitamin B3 is an important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. Niacinamide is used to increase the effect of radiation therapy on tumor cells. Niacin (nicotinic acid) and niacinamide, while both labeled as vitamin B3 also have different applications. Niacinamide is useful in arthritis and early-onset type I diabetes while niacin is an effective reducer of high cholesterol levels.
Niacinamide is a metabolite found in or produced by Saccharomyces cerevisiae.
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
See also: Adenosine; Niacinamide (component of); Dapsone; niacinamide (component of); Adenosine; Niacinamide; Titanium Dioxide (component of) ... View More ...
Niacinamide, also known as nicotinamide (NAM), is a form of vitamin B3 found in food and used as a dietary supplement and medication. Niacinamide belongs to the class of organic compounds known as nicotinamides. These are heterocyclic aromatic compounds containing a pyridine ring substituted at position 3 by a carboxamide group. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. The structure of nicotinamide consists of a pyridine ring to which a primary amide group is attached in the meta position. It is an amide of nicotinic acid. As an aromatic compound, it undergoes electrophilic substitution reactions and transformations of its two functional groups. Niacinamide and phosphoribosyl pyrophosphate can be converted into nicotinic acid mononucleotide and phosphate by the enzyme nicotinamide phosphoribosyltransferase. In humans, niacinamide is involved in the metabolic disorder called the nad+ signalling pathway (cancer). Niacinamide is an odorless tasting compound. Outside of the human body, niacinamide is found, on average, in the highest concentration within a few different foods, such as common sages, cow milk, and cocoa beans and in a lower concentration in common pea. Niacinamide has also been detected, but not quantified in several different foods, such as yardlong beans, roselles, apples, oyster mushrooms, and swiss chards. Niacinamide occurs in trace amounts mainly in meat, fish, nuts, and mushrooms, as well as to a lesser extent in some vegetables. It is commonly added to cereals and other foods. Many multivitamins contain 20–30 mg of vitamin B3 and it is also available in higher doses. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
COVID info from COVID-19 Disease Map, WikiPathways, PDB, Protein Data Bank, clinicaltrial, clinicaltrials, clinical trial, clinical trials
A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Widespread in plants, e.g. rice, yeast and fungi. Dietary supplement, may be used in infant formulas

Nicotinamide. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=98-92-0 (retrieved 2024-07-01) (CAS RN: 98-92-0). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity[1][2][3][4].
Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity[1][2][3][4].
Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity[1][2][3][4].

同义名列表

284 个代谢物同义名

Nicotinamide, BioReagent, suitable for cell culture, suitable for insect cell culture; Niacinamide, Pharmaceutical Secondary Standard; Certified Reference Material; Niacinamide, United States Pharmacopeia (USP) Reference Standard; Nicotinamide, European Pharmacopoeia (EP) Reference Standard; Nicotinamide, British Pharmacopoeia (BP) Reference Standard; Niacinamide;Nicotinic acid amide;Vitamin B3; Vitamin PP; InChI=1/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9; Derma Pella Cleanser for Sensitive and Dry Skin; Nicotinamide (Niacinamide), analytical standard; SISEUNDEUSI LUMINANT MASK PACK STEP2(WHITENING); LEBODY LAB RENEWAL DUAL EFFECT IDEBENONE SERUM; PAPA RECIPE BOMBEE BRIGHTENING HONEY MASK PACK; MUSTUS DAILY HARVEST SQUEEZE TONE UP MASK PACK; Niacinamide, meets USP testing specifications; Nicotinamide, Vetec(TM) reagent grade, >=98\\%; The Hayan Cherry Blossom Brightening Essence; LEBODY LAB RENEWAL DUAL EFFECT PEPTIDE SERUM; Derma Pella Facial Cleanser for Normal Skin; Niacinamide;Nicotinic acid amide;Vitamin B3; AROCELL X BELLE J SUPER POWER CELL AMPOULE; J9 ULTRA ADVANCED INTENSIVE SCALP SERUM V2; Nicotinamide, tested according to Ph.Eur.; Nicotinamide 10 microg/mL in Acetonitrile; DERMAHAN THE WHITENING MOISTURIZING MASK; MIZON ENJOY VITAL UP TIME Whitening Mask; DERLADIE HerbalExtract BodySolution MIST; Bk Cell 5days Of Secret Snow Whitening; DR.ALTHEA POWER WHITENING GLUTATHIONE; Skin Project Ya Cooling Celluven Mask; AN ADC SP INTENSIVE MOISTURE ESSENCE; THE SKIN HOUSE Vital Bright EyeCream; THE SKIN HOUSE Vital Bright Emulsion; FRESH MANDARIN AROMATHERAPY MASK27g; COSMEPURE BRIGHTENING CALMING TONER; Nicotinamide, puriss., 99.0-101.0\\%; Niveola P.H.c 3d Festival Mask Pack; Nicotinamide, >=98\\% (HPLC), powder; THE SKIN HOUSE Vital BrightEmulsion; ARILAC Brightening Mask Sheet Pack; Nicotinamide 1.0 mg/ml in Methanol; DR. GLODERM TIME TO WHITENING MASK; THE SKIN HOUSE Vital Bright Toner; Cellpium premiumEX hybrid essence; Ala-C Snail Cell Reparing Essence; Amid kyseliny nikotinove [Czech]; THE SKIN HOUSE Vital BrightSerum; EVECODE THREAD LIFTING MASK PACK; Pharmagenix brand OF niacinamide; THE SKIN HOUSE Vital BrightCream; Nicotinamide, niacin, vitamin B3; Pyridine-3-carboxylic acid amide; Daily Whitening Care Sheet Mask; Cellpium premiumEX hybrid toner; Edge Cutimal Cat Whitening Mask; Revital Perfecting Dual Ampoule; Cellpium super richness ampoule; NIACIN (AS NIACINAMIDE) [VANDF]; 3-Pyridinecarboxylic acid amide; by selected hyaluron day serum; Jenapharm brand OF niacinamide; SFERANGS VITA C CAPSULEBOOSTER; Nicotinamide, >=98.5\\% (HPLC); CAVIALL Wrinkle-Free PowerTox; Cellpium double essence toner; Shieldlife Whitening Ion Mask; Ultra Whitening First Essence; NYAAM NYAAM Skin Reborn Serum; Nicotinamide, >=99.5\\% (HPLC); Primerose Snail Hydro Essence; Dr Cellinme Skin Care Ampoule; COSMEPURE BRIGHTENING CALMING; Niacinamide pharmagenix brand; NIACINAMIDE COMPONENT OF TPN; AAPE Continuous Renewal Mask; NICOTINAMIDUM [WHO-IP LATIN]; DR. GLODERM TABRX WHITENING; Jenapharm, Nicotinsäureamid; NICOTINAMIDE (EP MONOGRAPH); NIACINAMIDE [USP MONOGRAPH]; BRIGHTUNING PEPTIDE AMPOULE; Niacinamide jenapharm brand; NIACINAMIDE (USP MONOGRAPH); Miracle Moisturizer Essence; NICOTINAMIDE [EP MONOGRAPH]; Astra brand OF niacinamide; DPC Whitening Booster Mask; Nicotinsäureamid Jenapharm; .beta.-Pyridinecarboxamide; Pellagra-Preventing Factor; Nikotinsaeureamid [German]; Nicotinamida (INN-Spanish); Nicotinamida [INN-Spanish]; Merck brand OF niacinamide; AAPE Nutrient Facial Toner; NICOTINAMIDE (EP IMPURITY); NICOTINAMIDE [EP IMPURITY]; AROCELL TIME REVERSE K I T; Nicotinamidum (INN-Latin); Nicotinamidum [INN-Latin]; Nicotinsaureamid [German]; Nicotinamide (Vitamin B3); TPN COMPONENT NIACINAMIDE; m-(Aminocarbonyl)pyridine; CELLBN MILKY TONE-UPCREAM; NYAAM NYAAM Peptide Serum; 3-(aminocarbonyl)pyridine; NIACINAMIDE [ORANGE BOOK]; Pyridine-3-carboxylamide; Nicotinamide-(amide-15N); beta-Pyridinecarboxamide; Amid kyseliny nikotinove; Miracle Laser Skin Mist; Niacinamide merck brand; Nicotinamide (Standard); Niacinamide astra brand; Ultra V AQUA SHINE MASK; CELLPIUM REAL MASK PACK; Nicotinamide (JP17/INN); Niacin (as niacinamide); Pyridine, 3-carbamoyl-; NYAAM NYAAM Vita Serum; Vita C Bright EyeCream; Dr Cellinme Mask Sheet; pyridine-3-carboxamide; Ultra Whitening Ample; Niacinamide Face Mask; 3-Pyridinecarboxamide; Royal Ginseng Essence; NICOTINAMIDE [WHO-IP]; Nicotinamidum (Latin); b-Pyridinecarboxamide; DPC Aura Booster Mask; Β-pyridinecarboxamide; NICOTINAMIDE [WHO-DD]; 3 Pyridinecarboxamide; NICOTINAMIDE (MART.); Dr. Color Effect Red; NICOTINAMIDUM [HPUS]; NIACINAMIDE (USP-RS); Mediatric (Salt/Mix); Nicotinic acid amide; Fantastic LightCream; MOISTIE PURE ESSENCE; NIACINAMIDE [USP-RS]; NICOTINAMIDE [MART.]; NIACINAMIDE [VANDF]; niacin - Vitamin B3; INTOMEDI HR PEPTIDE; Royal GinsengLotion; Nicotine acid amide; 3-Carbamoylpyridine; Vita C Bright Serum; Vita C Bright Toner; RGO HYDRATION TONER; Royal Ginseng Toner; APLIN SPOT ALL KILL; NICOTINAMIDE [JAN]; NIACINAMIDE [INCI]; NIACINAMIDE [HSDB]; Niacinamide [USAN]; JUVEHEAL W Ampoule; Nicotinamide [INN]; APLIN SPOT REMOVER; Royal GinsengCream; TANIA PURE ESSENCE; VITA C BRIGHTCREAM; TOAS Rejuvenation; Ginseng Whitening; KARATICA I M CURE; Niacinamide [USP]; CellExosome HE HR; NIACINAMIDE [FCC]; Niacinamide (USP); AAPE Skin Ampoule; Nikotinsaeureamid; Nicotinsaeureamid; NICOTINAMIDE [MI]; Nicotinamide,(S); Nicotinate amide; Nicotinsaureamid; Vitamin B3 amide; NIACINAMIDE (II); NIACINAMIDE [II]; Nicotinic amide; UNII-25X51I8RD4; TANIA PURECREAM; Costem cell 5 N; Ultra Whitening; Vitamin B (VAN); 3-Amidopyridine; CellExosome HR; CellExosome SB; Tox21_111202_1; Nicotililamido; Pahaba Control; Nicotine amide; nicotin-amide; Niacotinamide; Nicotylamidum; WLN: T6NJ CVZ; Pelonin amide; Delonin amide; Nicotinamidum; Tox21_201716; B 3, Vitamin; Nicotinamide; Nicotinamida; Austrovit PP; Tox21_302776; Nicosylamide; Tox21_111202; Nicotilamide; Nicotylamide; CAS-98-92-0; Nandervit-N; Nikotinamid; Niacinamide; Witamina PP; Inovitan PP; Propamine a; B3, Vitamin; Niocinamide; Nicotinamid; Vitamin B 3; Nicamindon; Niacinamid; Nicotamide; Nicovitina; Vi-Nicotyl; vitamin PP; Dr. Cellmo; Niko-tamin; Vitamin B3; Acid amide; Nictoamide; Nicosedine; Aminicotin; Celonia CM; 25X51I8RD4; Amixicotyn; NI-NICOTYL; Enduramide; Niavit PP; Mediatric; Nicosan 2; Vitamin B; Nicomidol; Savacotyl; Nicovitol; Amnicotin; Factor pp; PP-Faktor; Nicozymin; BREXTEM S; AI3-02906; Vi-noctyl; Nicobion; Nicamina; Amide PP; Hansamid; Endobion; Niozymin; Nicofort; Nicamide; Niacevit; Pelmine; Nicogen; Nicotol; Niamide; Dipigyl; Nicasir; Benicot; A11HA01; Papulex; Dipegyl; Nicovel; Nicamid; Nicovit; Pelmin; niacin; Nicota; 1yc5; NAM; Nicotinamide



数据库引用编号

51 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(22)

BioCyc(2)

PlantCyc(0)

代谢反应

1035 个相关的代谢反应过程信息。

Reactome(575)

BioCyc(55)

WikiPathways(2)

Plant Reactome(0)

INOH(3)

PlantCyc(387)

COVID-19 Disease Map(2)

PathBank(11)

  • Nicotinate and Nicotinamide Metabolism: NAD + Water ⟶ Adenosine monophosphate + Nicotinamide ribotide
  • Nicotinate and Nicotinamide Metabolism: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate
  • Nicotinate and Nicotinamide Metabolism: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate
  • Nicotinate and Nicotinamide Metabolism: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate
  • Nicotinate and Nicotinamide Metabolism: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate
  • NAD Salvage: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + Hydrogen Ion + L-Glutamic acid + NAD + Pyrophosphate
  • NAD Metabolism: N'-Formylkynurenine + Water ⟶ Formic acid + Hydrogen Ion + L-Kynurenine
  • NAD Salvage: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + Hydrogen Ion + L-Glutamic acid + NAD + Pyrophosphate
  • NAD+ Signalling Pathway (Cancer): Niacinamide + Phosphoribosyl pyrophosphate ⟶ Nicotinic acid mononucleotide + Phosphate
  • NAD+ Signalling and Aging: Niacinamide + Phosphoribosyl pyrophosphate ⟶ Nicotinic acid mononucleotide + Phosphate
  • Nicotinate and Nicotinamide Metabolism: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate

PharmGKB(0)

118 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Li Gao, Ai-Ping Zhang, Lei Fu, Qian-Wen Li, Xue-Mei Qin, Jing Zhao. Huangqin decoction attenuates spared nerve injury (SNI)-induced neuropathic pain by modulating microglial M1/M2 polarization partially mediated by intestinal nicotinamide metabolism. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155594. doi: 10.1016/j.phymed.2024.155594. [PMID: 38614040]
  • Xue-Xiu Yu, Ke-Xin Chen, Pan-Pan Yuan, Yu-He Wang, Hua-Xiao Li, Yun-Xiu Zhao, Yi-Jun Dai. Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit-like amidase mediates the degradation of insecticide flonicamid by Variovorax boronicumulans CGMCC 4969. The Science of the total environment. 2024 Jun; 928(?):172479. doi: 10.1016/j.scitotenv.2024.172479. [PMID: 38621543]
  • Mengqing Deng, Tianxiang Xiao, Xiyue Xu, Wenxiu Wang, Zhiming Yang, Kai Lu. Nicotinamide deficiency promotes imidacloprid resistance via activation of ROS/CncC signaling pathway-mediated UGT detoxification in Nilaparvata lugens. The Science of the total environment. 2024 May; 926(?):172035. doi: 10.1016/j.scitotenv.2024.172035. [PMID: 38565349]
  • Mohammad Hasan Maleki, Morvarid Siri, Amirhossein Jafarabadi, Mahsa Rajabi, Seyed Amirhossein Mazhari, Zahra Noori, Farhad Koohpeyma, Amirreza Dehghanian, Nafiseh Esmaeili, Zeinab Aryanian, Sanaz Dastghaib. Boosting wound healing in diabetic rats: The role of nicotinamide riboside and resveratrol in UPR modulation and pyroptosis inhibition. International immunopharmacology. 2024 May; 132(?):112013. doi: 10.1016/j.intimp.2024.112013. [PMID: 38583241]
  • Xiong Li, Na Hu, Yanshuang Li, Haisheng Tang, Xumei Huang, Ting Yang, Jianchu Xu. Integrated ultrastructural, physiological, transcriptomic, and metabolomic analysis uncovers the mechanisms by which nicotinamide alleviates cadmium toxicity in Pistia stratiotes L. Journal of hazardous materials. 2024 Apr; 467(?):133702. doi: 10.1016/j.jhazmat.2024.133702. [PMID: 38330649]
  • Antonia Schuhmann, Janna Schulte, Heike Feldhaar, Ricarda Scheiner. Bumblebees are resilient to neonicotinoid-fungicide combinations. Environment international. 2024 Apr; 186(?):108608. doi: 10.1016/j.envint.2024.108608. [PMID: 38554503]
  • Ningbo Wang, Zeming Zhang, Yinan Wang, Liuquan Zhang, Aili Sun, Hua Liu, Xizhi Shi. Comparative antioxidant and metabolomic analysis for the identification of differential response of mussel (Mytilus coruscus) to four succinate dehydrogenase inhibitor fungicides. Environmental science and pollution research international. 2024 Mar; 31(11):16819-16831. doi: 10.1007/s11356-024-32309-x. [PMID: 38324158]
  • Jichang Song, Hui Qiu, Xianghao Meng, Shengxue Li, Yushuai Mao, Lu Zhang, Yiqiang Cai, Jianxin Wang, Mingguo Zhou, Yabing Duan. Risk assessment and molecular mechanism of Sclerotium rolfsii resistance to boscalid. Pesticide biochemistry and physiology. 2024 Mar; 200(?):105806. doi: 10.1016/j.pestbp.2024.105806. [PMID: 38582572]
  • F M Kasali, J N Kadima, J B Safari, A G Agaba, J Tusiimire, B A Witika. Effects of Physalis peruviana L. (leaf crude extracts) on blood glucose and functional biomarkers in streptozotocin-nicotinamide-induced diabetic rats. Die Pharmazie. 2024 Feb; 79(1):6-10. doi: 10.1691/ph.2024.3640. [PMID: 38509628]
  • Feyisayo O Adepoju, Ksenia V Sokolova, Irina F Gette, Irina G Danilova, Mikhail V Tsurkan, Alicia C Mondragon, Elena G Kovaleva, Jose Manuel Miranda. Protective Effect of Betulin on Streptozotocin-Nicotinamide-Induced Diabetes in Female Rats. International journal of molecular sciences. 2024 Feb; 25(4):. doi: 10.3390/ijms25042166. [PMID: 38396842]
  • A Abdulhamed, L Khaleel. CARDIOPROTECTIVE EFFECT OF GLYCYRRHIZA GLABRA EXTRACT AND GLYCYRRHIZA GLABRA SILVER NANOPARTICLE AGAINST ALLOXAN AND NICOTINAMIDE INDUCED DIABETIC CARDIAC INJURY IN RATS. Georgian medical news. 2024 Feb; ?(347):156-159. doi: ". [PMID: 38609134]
  • Xiaojing Wei, Yutian Tan, Jiaqi Huang, Ximing Dong, Weijie Feng, Tanglin Liu, Zhao Yang, Guiying Yang, Xiao Luo. N1-methylnicotinamide impairs gestational glucose tolerance in mice. Journal of molecular endocrinology. 2024 Feb; 72(2):. doi: 10.1530/jme-23-0126. [PMID: 38029302]
  • Konstantinos Samaras, Maria L Pappas, Alberto Pozzebon, George D Broufas. Pollen provisioning attenuates pesticide side-effects on a phytoseiid predator. Pest management science. 2024 Jan; ?(?):. doi: 10.1002/ps.7969. [PMID: 38294174]
  • Jue Li, Lusha Zhang, Teng Ge, Jiping Liu, Chuan Wang, Qi Yu. Understanding Sorafenib-Induced Cardiovascular Toxicity: Mechanisms and Treatment Implications. Drug design, development and therapy. 2024; 18(?):829-843. doi: 10.2147/dddt.s443107. [PMID: 38524877]
  • Lianzhu Zhou, Yongqiang Liu, Fanfang Kong, Shuangshuang Jia, Qi Wang, Zhongyue Wang, Hao Zhang, Xiaoqing Huang. Sensitivity of Botrytis cinerea from vineyards to Boscalid, Isofetamid and Pydiflumetofen in Shandong province, China. Phytopathology. 2023 Dec; ?(?):. doi: 10.1094/phyto-10-23-0369-kc. [PMID: 38105240]
  • Arman Syah Goli, Vilasinee Hirunpanich Sato, Hitoshi Sato, Savita Chewchinda, Jiraporn Leanpolchareanchai, Jannarin Nontakham, Jantana Yahuafai, Thavaree Thilavech, Pongsatorn Meesawatsom, Metawee Maitree. Antihyperglycemic effects of Lysiphyllum strychnifolium leaf extract in vitro and in vivo. Pharmaceutical biology. 2023 Dec; 61(1):189-200. doi: 10.1080/13880209.2022.2160771. [PMID: 36625086]
  • Mo Yi Yue, Rong Wang, Yan Min Liu, Bing Wei Chen, Wan-Long Ding, Yong Li. Resistance of ginseng gray mold pathogen, Botrytis cinerea, to boscalid and pyraclostrobin fungicides in China. Plant disease. 2023 Nov; ?(?):. doi: 10.1094/pdis-02-23-0321-re. [PMID: 38012822]
  • Nagalakshmi Kamaraj, Kadhirmathiyan Velumani, Ajay Guru, Praveen Kumar Issac. Antihyperglycemic activity of 14-deoxy, 11, 12-didehydro andrographolide on streptozotocin-nicotinamide induced type 2 diabetic rats. Molecular biology reports. 2023 Oct; ?(?):. doi: 10.1007/s11033-023-08878-4. [PMID: 37856062]
  • Rongjia Zhou, Bingxue Sun, Guangxue Zhu, Xuewen Xie, Ali Chai, Lei Li, Tengfei Fan, Baoju Li, Yanxia Shi. Monitoring in Corynespora cassiicola resistance to boscalid, trifloxystrobin, and carbendazim in China. Phytopathology. 2023 Sep; ?(?):. doi: 10.1094/phyto-06-23-0186-r. [PMID: 37665395]
  • Su Wu, Wenwei Ai, Lei Nie, Xiao Lu. Antidiabetic activity of eupafolin through peroxisome proliferator-activated receptor-gamma and PI3K/Akt signaling in Type 2 diabetic rats. Journal of biochemical and molecular toxicology. 2023 Aug; ?(?):e23463. doi: 10.1002/jbt.23463. [PMID: 37566541]
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