Cosmosiin (BioDeep_00000000234)

 

Secondary id: BioDeep_00000269935, BioDeep_00000400278, BioDeep_00000400529, BioDeep_00000859293

natural product human metabolite PANOMIX_OTCML-2023 Chemicals and Drugs


代谢物信息卡片


5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one;Apigenin 7-Glucoside

化学式: C21H20O10 (432.1056)
中文名称: 芹菜素-7-O-β-D-葡萄吡喃糖苷, 芹菜素-7-O-β-D-吡喃葡萄糖苷, 芹甙元-7-葡萄糖苷, 芹菜素-7-葡萄甙, 大波斯菊苷
谱图信息: 最多检出来源 Homo sapiens(natural_products) 16.96%

分子结构信息

SMILES: c1(cc(c2c(c1)oc(cc2=O)c1ccc(cc1)O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
InChI: InChI=1S/C21H20O10/c22-8-16-18(26)19(27)20(28)21(31-16)29-11-5-12(24)17-13(25)7-14(30-15(17)6-11)9-1-3-10(23)4-2-9/h1-7,16,18-24,26-28H,8H2

描述信息

Cosmosiin, also known as apigenin 7-O-glucoside or apigetrin, is a member of the class of compounds known as flavonoid-7-O-glycosides. Flavonoid-7-O-glycosides are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position. Cosmosiin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Cosmosiin can be found in a number of food items, such as common thyme, white lupine, common oregano, and orange mint. Cosmosiin can also be found in dandelion coffee and in Teucrium gnaphalodes (Wikipedia). Cosmosiin can also be found plants such as wild celery and anise. Cosmosiin has been shown to exhibit anti-platelet function (PMID: 21834233).
Apigenin 7-O-beta-D-glucoside is a glycosyloxyflavone that is apigenin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as a non-steroidal anti-inflammatory drug, a metabolite and an antibacterial agent. It is a beta-D-glucoside, a dihydroxyflavone, a glycosyloxyflavone and a monosaccharide derivative. It is functionally related to an apigenin. It is a conjugate acid of an apigenin 7-O-beta-D-glucoside(1-). It is an enantiomer of an apigenin 7-O-beta-L-glucoside.
Cosmosiin is a natural product found in Galeopsis tetrahit, Carex fraseriana, and other organisms with data available.
See also: Chamomile (part of).
Apiumetrin, also known as 7-O-beta-D-glucosyl-5,7,4-trihydroxyflavone or cosmosiin, is a member of the class of compounds known as flavonoid-7-o-glycosides. Flavonoid-7-o-glycosides are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position. Apiumetrin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Apiumetrin can be found in wild celery, which makes apiumetrin a potential biomarker for the consumption of this food product.
Acquisition and generation of the data is financially supported in part by CREST/JST.
Annotation level-1
Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside) exhibits significant anti-proliferative and antioxidant activity and scavenges reactive oxygen species (ROS)[1][2].
Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside) exhibits significant anti-proliferative and antioxidant activity and scavenges reactive oxygen species (ROS)[1][2].

同义名列表

97 个代谢物同义名

5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one;Apigenin 7-Glucoside; 5-Hydroxy-2-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one; 5-hydroxy-2-(4-hydroxyphenyl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one; 5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one; 5-hydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-one; 5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one; 4H-1-Benzopyran-4-one, 7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-, Apigenin 7-O-glucoside; 4H-1-Benzopyran-4-one, 7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-; 7-(.BETA.-D-GLUCOPYRANOSYLOXY)-5-HYDROXY-2-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; 4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-; 7-(beta-D-Glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-; 7-(Β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 7-(b-D-Glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside; Apigenin 7-glucoside, United States Pharmacopeia (USP) Reference Standard; 5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl b-D-glucopyranoside; 5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl β-D-glucopyranoside; Apigenin-7-O-glucoside 1000 microg/mL in Acetone:Dimethyl sulfoxide; Apigenin 7-glucoside, EuropePharmacopoeia (EP) Reference Standard; Apigenin 7-glucoside, primary pharmaceutical reference standard; APIGENIN 7-O-GLUCOSIDE (CONSTITUENT OF CHAMOMILE) [DSC]; APIGENIN 7-O-GLUCOSIDE (CONSTITUENT OF CHAMOMILE); 7-O-beta-D-Glucosyl-5,7,4-trihydroxyflavone; 4,5,7-Trihydroxyflavone 7-beta-D-glucoside; Apigenin 7-glucoside, analytical standard; 7-O-Β-D-glucosyl-5,7,4-trihydroxyflavone; 7-O-b-D-Glucosyl-5,7,4-trihydroxyflavone; 4’,5,7-Trihydroxyflavone 7-β-D-glucoside; 4,5,7-Trihydroxyflavone 7-β-D-glucoside; Apigenin 7-O-.beta.-D-glucopyranoside; Apigenin-7-O-.beta.-D-glucopyranoside; 4,5,7-TRIHYDROXYFLAVONE 7-GLUCOSIDE; Apigenin 7-O-beta-D-glucopyranoside; apigenin-7-O-beta-D-glucopyranoside; Apigenin, 7-beta-D-glucopyranoside; 7-O-beta-D-Glucopyranosylapigenin; Apigenin 7-O-beta-glucopyranoside; Apigetrin(Apigenin-7-O-glucoside); Apigenin-7-O-4C1-beta-D-glucoside; Apigenin 7-O-β-D-glucopyranoside; Apigenin-7-O-b-D-glucopyranoside; Apigenin 7-O-.beta.-D-glucoside; Apigenin 7-beta-glucopyranoside; 7-O-(.beta.-D-Glucosyl)apigenin; 7-O-Β-D-glucopyranosylapigenin; Apigenin 7-O-β-glucopyranoside; Apigenin-7-O-4C1-β-D-glucoside; 7-O-(beta-D-Glucosyl)apigenin; APIGENIN-7-GLUCOSIDE (USP-RS); APIGENIN-7-GLUCOSIDE [USP-RS]; Apigenin 7-O-beta-D-glucoside; 7-O-beta-D-glucosyl-apigenin; Apigenin 7-β-glucopyranoside; 7-O-beta-D-Glucosylapigenin; Apigenin 7-beta-D-glucoside; apigenin 7-O-beta-glucoside; Apigenin-7-O-|A-D-glucoside; Apigenin-7-O-β-D-glucoside; Apigenin 7-O-β-D-glucoside; Apigenin 7-O-b-D-glucoside; Apigenin 7-β-D-glucoside; Apigenin 7-O-β-glucoside; 7-O-Β-D-glucosylapigenin; (-)-Apigenin 7-glucoside; Apigenin-7-O-glucoside; Apigenin 7-O-glucoside; 4-ethynyl-1,1-biphenyl; apigenin-7-D-glucoside; apigenin-7-glucoside; Apigenin 7-glucoside; Spectrum3_001249; Spectrum4_001741; Spectrum2_001752; Spectrum5_000562; UNII-7OF2S66PCH; APIGETRIN [MI]; DivK1c_007023; MEGxp0_001431; KBio2_003224; KBio2_000656; KBio3_002258; KBio2_005792; Cosmosioside; KBio1_001967; Apiumetrin; Cosmosiine; 7OF2S66PCH; Cosmociin; Cosemetin; Cosmoside; cosmosiin; Apigetrin; cosmetin; 5-hydroxy-2-(4-hydroxyphenyl)-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-one; Apigenin-7-O-β-D-glucopyranoside; Apigenin 7-O-beta-D-glucoside



数据库引用编号

55 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

28 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(27)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

415 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 AIMP2, ANXA5, BCL2, CASP3, CASP9, MAPK8, PIK3CA, PTGS2, TLR4, TYR, VEGFA, XDH
Peripheral membrane protein 4 ACHE, ANXA5, GORASP1, PTGS2
Endosome membrane 1 TLR4
Endoplasmic reticulum membrane 2 BCL2, PTGS2
Nucleus 7 ACHE, AIMP2, BCL2, CASP3, CASP9, MAPK8, VEGFA
cytosol 9 AIMP2, ANXA5, BCL2, CASP3, CASP9, GPT, MAPK8, PIK3CA, XDH
nucleoplasm 2 CASP3, MAPK8
Cell membrane 3 ACHE, TLR4, TNF
Cytoplasmic side 1 GORASP1
lamellipodium 1 PIK3CA
Golgi apparatus membrane 1 GORASP1
Synapse 2 ACHE, MAPK8
cell surface 4 ACHE, TLR4, TNF, VEGFA
glutamatergic synapse 1 CASP3
Golgi apparatus 3 ACHE, GORASP1, VEGFA
Golgi membrane 2 GORASP1, INS
lysosomal membrane 1 GAA
neuromuscular junction 1 ACHE
neuronal cell body 2 CASP3, TNF
sarcolemma 1 ANXA5
Cytoplasm, cytosol 1 AIMP2
Lysosome 2 GAA, TYR
plasma membrane 6 ACHE, BCHE, GAA, PIK3CA, TLR4, TNF
Membrane 7 ACHE, AIMP2, ANXA5, BCL2, GAA, TLR4, VEGFA
axon 1 MAPK8
caveola 1 PTGS2
extracellular exosome 3 ANXA5, GAA, GPT
Lysosome membrane 1 GAA
endoplasmic reticulum 3 BCL2, PTGS2, VEGFA
extracellular space 7 ACHE, BCHE, IL6, INS, TNF, VEGFA, XDH
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 4 ACHE, PIK3CA, TLR4, TYR
adherens junction 1 VEGFA
intercalated disc 1 PIK3CA
mitochondrion 2 BCL2, CASP9
protein-containing complex 3 BCL2, CASP9, PTGS2
intracellular membrane-bounded organelle 2 GAA, TYR
Microsome membrane 1 PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 2 TLR4, TYR
Secreted 6 ACHE, BCHE, GAA, IL6, INS, VEGFA
extracellular region 8 ACHE, ANXA5, BCHE, GAA, IL6, INS, TNF, VEGFA
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
Extracellular side 1 ACHE
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 3 ANXA5, TLR4, TNF
Secreted, extracellular space, extracellular matrix 1 VEGFA
Melanosome membrane 1 TYR
Early endosome 1 TLR4
Golgi-associated vesicle 1 TYR
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 1 TNF
pore complex 1 BCL2
focal adhesion 1 ANXA5
cis-Golgi network 1 GORASP1
extracellular matrix 1 VEGFA
Peroxisome 1 XDH
basement membrane 1 ACHE
sarcoplasmic reticulum 1 XDH
collagen-containing extracellular matrix 1 ANXA5
secretory granule 1 VEGFA
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 1 TLR4
Zymogen granule membrane 1 ANXA5
neuron projection 1 PTGS2
phagocytic cup 2 TLR4, TNF
blood microparticle 1 BCHE
Lipid-anchor, GPI-anchor 1 ACHE
endosome lumen 1 INS
tertiary granule membrane 1 GAA
Melanosome 1 TYR
side of membrane 1 ACHE
myelin sheath 1 BCL2
lipopolysaccharide receptor complex 1 TLR4
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 BCHE, IL6, INS, PTGS2
platelet alpha granule lumen 1 VEGFA
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
transport vesicle 1 INS
azurophil granule membrane 1 GAA
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 GORASP1, INS
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
nuclear envelope lumen 1 BCHE
apoptosome 1 CASP9
vesicle membrane 1 ANXA5
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 GAA
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
aminoacyl-tRNA synthetase multienzyme complex 1 AIMP2
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
interleukin-6 receptor complex 1 IL6
endothelial microparticle 1 ANXA5
autolysosome lumen 1 GAA
BAD-BCL-2 complex 1 BCL2
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
[Isoform H]: Cell membrane 1 ACHE
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
caspase complex 1 CASP9
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Xuerong Zhao, Zhuoya Wang, Guanlin Wu, Lianhong Yin, Lina Xu, Ning Wang, Jinyong Peng. Apigenin-7-glucoside-loaded nanoparticle alleviates intestinal ischemia-reperfusion by ATF3/SLC7A11-mediated ferroptosis. Journal of controlled release : official journal of the Controlled Release Society. 2024 Jan; 366(?):182-193. doi: 10.1016/j.jconrel.2023.12.038. [PMID: 38145659]
  • Tawakaltu Abdulrasheed-Adeleke, Bashir Lawal, Eyuwa Ignatius Agwupuye, Yucheng Kuo, Amarachi Mary Eni, Okwukwe Faith Ekoh, Halimat Yusuf Lukman, Amos S Onikanni, Femi Olawale, Sani Saidu, Yunusa O Ibrahim, Maliha Abdullah Saleh Al Ghamdi, Sarah S Aggad, Abdulrahman A Alsayegh, Nada H Aljarba, Gaber El-Saber Batiha, Alexander T H Wu, Hsu-Shan Huang. Apigetrin-enriched Pulmeria alba extract prevents assault of STZ on pancreatic β-cells and neuronal oxidative stress with concomitant attenuation of tissue damage and suppression of inflammation in the brain of diabetic rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Mar; 162(?):114582. doi: 10.1016/j.biopha.2023.114582. [PMID: 36989727]
  • Gabin Thierry M Bitchagno, Anja Schüffler, Jonathan Gross, Matthias Krumb, Pierre Tane, Till Opatz. Sesquiterpene Lactones from Vernonia tufnelliae: Structural Characterization and Biological Evaluation. Journal of natural products. 2022 07; 85(7):1681-1690. doi: 10.1021/acs.jnatprod.2c00055. [PMID: 35704432]
  • Jun Gu Kim, Jin Woo Lee, Thi Phuong Linh Le, Jae Sang Han, Yong Beom Cho, Haeun Kwon, Dongho Lee, Mi Kyeong Lee, Bang Yeon Hwang. Sesquiterpenoids from Chrysanthemum indicum with Inhibitory Effects on NO Production. Journal of natural products. 2021 03; 84(3):562-569. doi: 10.1021/acs.jnatprod.0c01121. [PMID: 33667099]
  • Miao-Miao Liu, Run-Hui Ma, Zhi-Jing Ni, Kiran Thakur, Carlos L Cespedes-Acuña, Li Jiang, Zhao-Jun Wei. Apigenin 7-O-glucoside promotes cell apoptosis through the PTEN/PI3K/AKT pathway and inhibits cell migration in cervical cancer HeLa cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2020 Dec; 146(?):111843. doi: 10.1016/j.fct.2020.111843. [PMID: 33152472]
  • Wei Wang, Ru-Feng Yue, Zhen Jin, Li-Min He, Rong Shen, Dan Du, You-Zhi Tang. Efficiency comparison of apigenin-7-O-glucoside and trolox in antioxidative stress and anti-inflammatory properties. The Journal of pharmacy and pharmacology. 2020 Nov; 72(11):1645-1656. doi: 10.1111/jphp.13347. [PMID: 32743812]
  • Young Hye Seo, Tuy An Trinh, Seung Mok Ryu, Hyo Seon Kim, Goya Choi, Byeong Cheol Moon, Sang Hee Shim, Dae Sik Jang, Dongho Lee, Ki Sung Kang, Jun Lee. Chemical Constituents from the Aerial Parts of Elsholtzia ciliata and Their Protective Activities on Glutamate-Induced HT22 Cell Death. Journal of natural products. 2020 10; 83(10):3149-3155. doi: 10.1021/acs.jnatprod.0c00756. [PMID: 32991171]
  • Ewa Witkowska-Banaszczak, Violetta Krajka-Kuźniak, Katarzyna Papierska. The effect of luteolin 7-glucoside, apigenin 7-glucoside and Succisa pratensis extracts on NF-κB activation and α-amylase activity in HepG2 cells. Acta biochimica Polonica. 2020 Mar; 67(1):41-47. doi: 10.18388/abp.2020_2894. [PMID: 32129972]
  • Young H Seo, Shin-Young Kang, Ji-Sun Shin, Seung M Ryu, A Y Lee, Goya Choi, Byeong C Moon, Dae-Sik Jang, Sang H Shim, Dongho Lee, Kyung-Tae Lee, Jun Lee. Chemical Constituents from the Aerial Parts of Agastache rugosa and Their Inhibitory Activities on Prostaglandin E2 Production in Lipopolysaccharide-Treated RAW 264.7 Macrophages. Journal of natural products. 2019 12; 82(12):3379-3385. doi: 10.1021/acs.jnatprod.9b00697. [PMID: 31747281]
  • Perihan Koysu, Nusret Genc, Mahfuz Elmastas, Huseyin Aksit, Ramazan Erenler. Isolation, identification of secondary metabolites from Salvia absconditiflora and evaluation of their antioxidative properties. Natural product research. 2019 Dec; 33(24):3592-3595. doi: 10.1080/14786419.2018.1488700. [PMID: 30445824]
  • Beligh Mechri, Meriem Tekaya, Mohamed Hammami, Hechmi Chehab. Root verbascoside and oleuropein are potential indicators of drought resistance in olive trees (Olea europaea L.). Plant physiology and biochemistry : PPB. 2019 Aug; 141(?):407-414. doi: 10.1016/j.plaphy.2019.06.024. [PMID: 31228797]
  • Xinqiao Zhan, Qingwen Shen, Jie Chen, Pei Yang, Xuemin Wang, Yueyun Hong. Rice sulfoquinovosyltransferase SQD2.1 mediates flavonoid glycosylation and enhances tolerance to osmotic stress. Plant, cell & environment. 2019 07; 42(7):2215-2230. doi: 10.1111/pce.13554. [PMID: 30942482]
  • Sachiko Sugimoto, Yoshi Yamano, Samar Y Desoukey, Kazuaki Katakawa, Amira S Wanas, Hideaki Otsuka, Katsuyoshi Matsunami. Isolation of Sesquiterpene-Amino Acid Conjugates, Onopornoids A-D, and a Flavonoid Glucoside from Onopordum alexandrinum. Journal of natural products. 2019 06; 82(6):1471-1477. doi: 10.1021/acs.jnatprod.8b00948. [PMID: 31199638]
  • M Villalva, L Jaime, D Villanueva-Bermejo, B Lara, T Fornari, G Reglero, S Santoyo. Supercritical anti-solvent fractionation for improving antioxidant and anti-inflammatory activities of an Achillea millefolium L. extract. Food research international (Ottawa, Ont.). 2019 01; 115(?):128-134. doi: 10.1016/j.foodres.2018.08.027. [PMID: 30599924]
  • Fatma Hadrich, Sami Sayadi. Apigetrin inhibits adipogenesis in 3T3-L1 cells by downregulating PPARγ and CEBP-α. Lipids in health and disease. 2018 Apr; 17(1):95. doi: 10.1186/s12944-018-0738-0. [PMID: 29695233]
  • Elina Karhu, Janne Isojärvi, Pia Vuorela, Leena Hanski, Adyary Fallarero. Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy. Journal of natural products. 2017 10; 80(10):2602-2608. doi: 10.1021/acs.jnatprod.6b01052. [PMID: 29043803]
  • Xinqiao Zhan, Qingwen Shen, Xuemin Wang, Yueyun Hong. The Sulfoquinovosyltransferase-like Enzyme SQD2.2 is Involved in Flavonoid Glycosylation, Regulating Sugar Metabolism and Seed Setting in Rice. Scientific reports. 2017 07; 7(1):4685. doi: 10.1038/s41598-017-04002-2. [PMID: 28680100]
  • Laura Flores-Bocanegra, Martin González-Andrade, Robert Bye, Edelmira Linares, Rachel Mata. α-Glucosidase Inhibitors from Salvia circinata. Journal of natural products. 2017 05; 80(5):1584-1593. doi: 10.1021/acs.jnatprod.7b00155. [PMID: 28422509]
  • Minjuan Bian, Yong Zhang, Xiaoye Du, Jing Xu, Jingang Cui, Jiangping Gu, Weiliang Zhu, Teng Zhang, Yu Chen. Apigenin-7-diglucuronide protects retinas against bright light-induced photoreceptor degeneration through the inhibition of retinal oxidative stress and inflammation. Brain research. 2017 05; 1663(?):141-150. doi: 10.1016/j.brainres.2017.03.019. [PMID: 28336272]
  • Lucas B Bolzon, Joicy S Dos Santos, Denise B Silva, Eduardo J Crevelin, Luiz A B Moraes, Norberto P Lopes, Marilda D Assis. Apigenin-7-O-glucoside oxidation catalyzed by P450-bioinspired systems. Journal of inorganic biochemistry. 2017 05; 170(?):117-124. doi: 10.1016/j.jinorgbio.2017.02.016. [PMID: 28236787]
  • Peng-Fei Yang, Zi-Ming Feng, Ya-Nan Yang, Jian-Shuang Jiang, Pei-Cheng Zhang. Neuroprotective Caffeoylquinic Acid Derivatives from the Flowers of Chrysanthemum morifolium. Journal of natural products. 2017 04; 80(4):1028-1033. doi: 10.1021/acs.jnatprod.6b01026. [PMID: 28248102]
  • Yanrong Zhu, Shouyin Di, Wei Hu, Yingda Feng, Qing Zhou, Bing Gong, Xinlong Tang, Juntian Liu, Wei Zhang, Miaomiao Xi, Lin Jiang, Chao Guo, Jingyi Cao, Chongxi Fan, Zhiqiang Ma, Yang Yang, Aidong Wen. A new flavonoid glycoside (APG) isolated from Clematis tangutica attenuates myocardial ischemia/reperfusion injury via activating PKCε signaling. Biochimica et biophysica acta. Molecular basis of disease. 2017 03; 1863(3):701-711. doi: 10.1016/j.bbadis.2016.12.013. [PMID: 28024940]
  • Etil Guzelmeric, Petar Ristivojević, Irena Vovk, Dušanka Milojković-Opsenica, Erdem Yesilada. Quality assessment of marketed chamomile tea products by a validated HPTLC method combined with multivariate analysis. Journal of pharmaceutical and biomedical analysis. 2017 Jan; 132(?):35-45. doi: 10.1016/j.jpba.2016.09.030. [PMID: 27693951]
  • Hye-Sun Lim, Ohn-Soon Kim, Bu-Yeo Kim, Soo-Jin Jeong. Apigetrin from Scutellaria baicalensis Georgi Inhibits Neuroinflammation in BV-2 Microglia and Exerts Neuroprotective Effect in HT22 Hippocampal Cells. Journal of medicinal food. 2016 Nov; 19(11):1032-1040. doi: 10.1089/jmf.2016.0074. [PMID: 27845861]
  • Bo Liu, Yu-Zhen Xie, Xiao-Xiu Li, Ying-Ying Sun, Fang Xu, Teng-Fei Ji. [Chemical constituents of Myripnois dioica]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2016 Sep; 41(17):3260-3264. doi: 10.4268/cjcmm20161723. [PMID: 28920380]
  • Malek Besbes Hlila, Habib Mosbah, Nahla Zanina, Aymen Ben Nejma, Hichem Ben Jannet, Mahjoub Aouni, Boulbaba Selmi. Characterisation of phenolic antioxidants in Scabiosa arenaria flowers by LC-ESI-MS/MS and NMR. The Journal of pharmacy and pharmacology. 2016 Jul; 68(7):932-40. doi: 10.1111/jphp.12561. [PMID: 27230582]
  • Nouha Nasr-Bouzaiene, Aicha Sassi, Ahmed Bedoui, Mounira Krifa, Leila Chekir-Ghedira, Kamel Ghedira. Immunomodulatory and cellular antioxidant activities of pure compounds from Teucrium ramosissimum Desf. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2016 Jun; 37(6):7703-12. doi: 10.1007/s13277-015-4635-0. [PMID: 26692099]
  • Ilina Krasteva, Viktor Bratkov, Franz Bucar, Olaf Kunert, Manfred Kollroser, Magdalena Kondeva-Burdina, Iliana Ionkova. Flavoalkaloids and Flavonoids from Astragalus monspessulanus. Journal of natural products. 2015 Nov; 78(11):2565-71. doi: 10.1021/acs.jnatprod.5b00502. [PMID: 26558405]
  • Medine Gulluce, Furkan Orhan, Derya Yanmis, Tulin Arasoglu, Zuhal Guvenalp, Lutfiye Omur Demirezer. Isolation of a flavonoid, apigenin 7-O-glucoside, from Mentha longifolia (L.) Hudson subspecies longifolia and its genotoxic potency. Toxicology and industrial health. 2015 Sep; 31(9):831-40. doi: 10.1177/0748233713475511. [PMID: 23377117]
  • Chi-Chih Chang, Sheau Ling Ho, Shoei-Sheng Lee. Acylated glucosylflavones as α-glucosidase inhibitors from Tinospora crispa leaf. Bioorganic & medicinal chemistry. 2015 Jul; 23(13):3388-96. doi: 10.1016/j.bmc.2015.04.053. [PMID: 25999202]
  • Mihyang Kim, Jaekwan Lee, Jaehong Han. Deglycosylation of isoflavone C-glycosides by newly isolated human intestinal bacteria. Journal of the science of food and agriculture. 2015 Jul; 95(9):1925-31. doi: 10.1002/jsfa.6900. [PMID: 25199800]
  • Imen Samet, Myra O Villareal, Hideko Motojima, Junkyu Han, Sami Sayadi, Hiroko Isoda. Olive leaf components apigenin 7-glucoside and luteolin 7-glucoside direct human hematopoietic stem cell differentiation towards erythroid lineage. Differentiation; research in biological diversity. 2015 Jun; 89(5):146-55. doi: 10.1016/j.diff.2015.07.001. [PMID: 26299581]
  • Qiang Wei, Xiao-ying Ji, Fei Xu, Qian-rong Li, Hao Yin. [Chemical Constituents from Leaves of Hibiscus syriacus and Their α-Glucosidase Inhibitory Activities]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2015 May; 38(5):975-9. doi: . [PMID: 26767290]
  • Etil Guzelmeric, Irena Vovk, Erdem Yesilada. Development and validation of an HPTLC method for apigenin 7-O-glucoside in chamomile flowers and its application for fingerprint discrimination of chamomile-like materials. Journal of pharmaceutical and biomedical analysis. 2015 Mar; 107(?):108-18. doi: 10.1016/j.jpba.2014.12.021. [PMID: 25575175]
  • Bui Thi Thuy Luyen, Bui Huu Tai, Nguyen Phuong Thao, Ji Yun Cha, Hoon Yeon Lee, Young Mi Lee, Young Ho Kim. Anti-inflammatory components of Chrysanthemum indicum flowers. Bioorganic & medicinal chemistry letters. 2015 Jan; 25(2):266-9. doi: 10.1016/j.bmcl.2014.11.054. [PMID: 25497988]
  • Liwu Chen, Jian Du, Qiwen Dai, Hongcheng Zhang, Wensheng Pang, Juan Hu. Prediction of anti-tumor chemical probes of a traditional Chinese medicine formula by HPLC fingerprinting combined with molecular docking. European journal of medicinal chemistry. 2014 Aug; 83(?):294-306. doi: 10.1016/j.ejmech.2014.06.037. [PMID: 24974349]
  • Gülcan Ozkan, Mehmet Musa Ozcan. Some phenolic compounds of extracts obtained from Origanum species growing in Turkey. Environmental monitoring and assessment. 2014 Aug; 186(8):4947-57. doi: 10.1007/s10661-014-3750-5. [PMID: 24691738]
  • Hui-Peng Song, Hui Zhang, Yu Fu, Hua-yan Mo, Mu Zhang, Jun Chen, Ping Li. Screening for selective inhibitors of xanthine oxidase from Flos Chrysanthemum using ultrafiltration LC-MS combined with enzyme channel blocking. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2014 Jun; 961(?):56-61. doi: 10.1016/j.jchromb.2014.05.001. [PMID: 24861872]
  • Dinesh Kumar, Zulfiqar Ali Bhat. Apigenin 7-glucoside from Stachys tibetica Vatke and its anxiolytic effect in rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2014 Jun; 21(7):1010-4. doi: 10.1016/j.phymed.2013.12.001. [PMID: 24462214]
  • Yan-Xia Yang, Fu-Lin Yan, Xiang Wang. [Chemical constituents from Punica granatum flowers]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2014 May; 37(5):804-7. doi: . [PMID: 25335287]
  • Eri Nakazaki, Soninkhishig Tsolmon, Junkyu Han, Hiroko Isoda. Proteomic study of granulocytic differentiation induced by apigenin 7-glucoside in human promyelocytic leukemia HL-60 cells. European journal of nutrition. 2013 Feb; 52(1):25-35. doi: 10.1007/s00394-011-0282-4. [PMID: 22113421]
  • Wei-Quan Chen, Zhi-Jun Song, Han-Hong Xu. A new antifungal and cytotoxic C-methylated flavone glycoside from Picea neoveitchii. Bioorganic & medicinal chemistry letters. 2012 Sep; 22(18):5819-22. doi: 10.1016/j.bmcl.2012.07.089. [PMID: 22901896]
  • Zaixing Chen, Xixiang Ying, Shu Meng, Xu Zhu, Hong Jiang, Qishen Cao, Lin Wang, Fanhao Meng. LC determination of luteolin-7-O-β-D-glucoside and apigenin-7-O-β-D-glucoside in rat plasma after administration of Humulus scandens extract and its application to pharmacokinetic studies. Natural product research. 2012; 26(6):530-9. doi: 10.1080/14786419.2010.532127. [PMID: 21756194]
  • S Vargas, K Ndjoko Ioset, A-E Hay, J-R Ioset, S Wittlin, K Hostettmann. Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation. Journal of pharmaceutical and biomedical analysis. 2011 Dec; 56(5):880-6. doi: 10.1016/j.jpba.2011.06.026. [PMID: 21872416]
  • Nabila Zaabat, Anne-Emmanuelle Hay, Serge Michalet, Nicole Darbour, Christine Bayet, Inès Skandrani, Leila Chekir-Ghedira, Salah Akkal, Marie-Geneviève Dijoux-Franca. Antioxidant and antigenotoxic properties of compounds isolated from Marrubium deserti de Noé. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2011 Dec; 49(12):3328-35. doi: 10.1016/j.fct.2011.08.026. [PMID: 21924316]
  • Ozlem Baris, Mehmet Karadayi, Derya Yanmis, Zuhal Guvenalp, Tugba Bal, Medine Gulluce. Isolation of 3 flavonoids from Mentha longifolia (L.) Hudson subsp. longifolia and determination of their genotoxic potentials by using the E. coli WP2 test system. Journal of food science. 2011 Nov; 76(9):T212-7. doi: 10.1111/j.1750-3841.2011.02405.x. [PMID: 22416730]
  • Xue-Jing Peng, Chong Li. [Study on the flavanone constitutes of Buddleja davidii]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2011 Oct; 34(10):1534-7. doi: . [PMID: 22372140]
  • Shan Qin, Xuesen Wen. [Simultaneous determination of 6 active components in Chrysanthemum morifolium by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2011 Jun; 36(11):1474-7. doi: 10.4268/cjcmm20111115. [PMID: 22779181]
  • Mostafa Hojati, Seyed Ali Mohammad Modarres-Sanavy, Faezeh Ghanati, Mehdi Panahi. Hexaconazole induces antioxidant protection and apigenin-7-glucoside accumulation in Matricaria chamomilla plants subjected to drought stress. Journal of plant physiology. 2011 May; 168(8):782-91. doi: 10.1016/j.jplph.2010.11.009. [PMID: 21208683]
  • Zaixing Chen, Xixiang Ying, Shu Meng, Xu Zhu, Hong Jiang, Qishen Cao, Xuying Li, Fanhao Meng. High-performance liquid chromatographic determination and pharmacokinetic study of apigenin-7-O-β-D-glucoside in rat plasma after intravenous administration. Archives of pharmacal research. 2011 May; 34(5):741-6. doi: 10.1007/s12272-011-0507-3. [PMID: 21656359]
  • D I Pisarev, O O Novikov, M Yu Novikova, E T Zhilyakova. Flavonoid composition of Juniperus oblonga Bieb. Bulletin of experimental biology and medicine. 2011 Apr; 150(6):714-7. doi: 10.1007/s10517-011-1231-1. [PMID: 22235425]
  • Sara Vitalini, Giangiacomo Beretta, Marcello Iriti, Simone Orsenigo, Nicoletta Basilico, Stefano Dall'Acqua, Maria Iorizzi, Gelsomina Fico. Phenolic compounds from Achillea millefolium L. and their bioactivity. Acta biochimica Polonica. 2011; 58(2):203-9. doi: 10.18388/abp.2011_2266. [PMID: 21503279]
  • Junxian Wang, Yuanyuan Zhang, Sheng Chen, Min Zhao, Lu Zhang. [Chemical constituents of Discocleidion rufescens]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2010 Jun; 35(11):1435-8. doi: . [PMID: 20822016]
  • Cüneyt Cirak, Jolita Radusiene, Valdimaras Janulis, Liudas Ivanauskas. Secondary metabolites of Hypericum confertum and their possible chemotaxonomic significance. Natural product communications. 2010 Jun; 5(6):897-8. doi: ". [PMID: 20614818]
  • Xing-Qi Tan, Liang-Jun Guo, Hai-Sheng Chen, Lin-Song Wu, Fei-Fei Kong. [Study on the flavonoids constituents of Trachelospermum jasminoides]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2010 Jan; 33(1):58-60. doi: ". [PMID: 20518306]
  • Liang Tao, Jincheng Huang, Yanping Zhao, Chong Li. [Chemical constituents in Buddleja albiflora]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2009 Dec; 34(23):3043-6. doi: ". [PMID: 20222420]
  • Prathan Luecha, Kaoru Umehara, Toshio Miyase, Hiroshi Noguchi. Antiestrogenic constituents of the Thai medicinal plants Capparis flavicans and Vitex glabrata. Journal of natural products. 2009 Nov; 72(11):1954-9. doi: 10.1021/np9006298. [PMID: 19943620]
  • Hyung Jae Jeong, Young Bae Ryu, Su-Jin Park, Jang Hoon Kim, Hyung-Jun Kwon, Jin Hyo Kim, Ki Hun Park, Mun-Chual Rho, Woo Song Lee. Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities. Bioorganic & medicinal chemistry. 2009 Oct; 17(19):6816-23. doi: 10.1016/j.bmc.2009.08.036. [PMID: 19729316]
  • Giovanni Agati, Giovanni Stefano, Stefano Biricolti, Massimiliano Tattini. Mesophyll distribution of 'antioxidant' flavonoid glycosides in Ligustrum vulgare leaves under contrasting sunlight irradiance. Annals of botany. 2009 Oct; 104(5):853-61. doi: 10.1093/aob/mcp177. [PMID: 19633310]
  • Kailan Zhou, Feng Zhao, Zhihui Liu, Yulei Zhuang, Lixia Chen, Feng Qiu. Triterpenoids and flavonoids from celery (Apium graveolens). Journal of natural products. 2009 Sep; 72(9):1563-7. doi: 10.1021/np900117v. [PMID: 19778086]
  • Ye Tian, Haifeng Tang, Xiaojuan Wang, Feng Qiu, Gaijin Xue, Jun Li. [Studies on antibacterial constituents of Discocleidion rufescens (2)]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2009 Jun; 34(11):1377-80. doi: . [PMID: 19771866]
  • Laura Hanske, Gunnar Loh, Silke Sczesny, Michael Blaut, Annett Braune. The bioavailability of apigenin-7-glucoside is influenced by human intestinal microbiota in rats. The Journal of nutrition. 2009 Jun; 139(6):1095-102. doi: 10.3945/jn.108.102814. [PMID: 19403720]
  • Yanyan Jiang, Renbing Shi, Bin Liu, Qiuying Wang, Ying Dai. [Studies on chemical components of Lobelia chinensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2009 Feb; 34(3):294-7. doi: . [PMID: 19445152]
  • Jun Li, Hua Jiang, Renbing Shi. A new acylated quercetin glycoside from the leaves of Stevia rebaudiana Bertoni. Natural product research. 2009; 23(15):1378-83. doi: 10.1080/14786410802447294. [PMID: 19809909]
  • Dong-Mei Ren, Zhi Qu, Xiao-Ning Wang, Jing Shi, Hong-Xiang Lou. Simultaneous determination of nine major active compounds in Dracocephalum rupestre by HPLC. Journal of pharmaceutical and biomedical analysis. 2008 Dec; 48(5):1441-5. doi: 10.1016/j.jpba.2008.09.013. [PMID: 18930620]
  • M Sharaf. Chemical constituents from the seeds of Trifolium alexandrinum. Natural product research. 2008 Dec; 22(18):1620-3. doi: 10.1080/14786410701869226. [PMID: 19085418]
  • Rafael Japón-Luján, Patricia Janeiro, María Dolores Luque de Castro. Solid-liquid transfer of biophenols from olive leaves for the enrichment of edible oils by a dynamic ultrasound-assisted approach. Journal of agricultural and food chemistry. 2008 Aug; 56(16):7231-5. doi: 10.1021/jf800748p. [PMID: 18656923]
  • Kazutoshi Shindo, Etsuko Saito, Miki Sekiya, Tomo Matsui, Yukiko Koike. Antioxidative activity of the flower of Torenia fournieri. Journal of natural medicines. 2008 Apr; 62(2):247-8. doi: 10.1007/s11418-007-0207-y. [PMID: 18404334]
  • Ya-Jun Wang, Xiu-Wwei Yang, Qiao-Sheng Guo. [Studies on chemical constituents in Huangjuhua (flowers of Chrysanthemum morifolium)]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2008 Mar; 33(5):526-30. doi: ". [PMID: 18536375]
  • Wei-Sheng Feng, Hong-Wei Li, Xiao-Ke Zheng, Hai-Xue Kuang, Sui-Qing Chen, Yan-Zhi Wang, Xin-Yu Zang. Chemical constituents from the leaves of Broussonetia papyrifera. Yao xue xue bao = Acta pharmaceutica Sinica. 2008 Feb; 43(2):173-80. doi: . [PMID: 18507345]
  • Janmejai K Srivastava, Sanjay Gupta. Antiproliferative and apoptotic effects of chamomile extract in various human cancer cells. Journal of agricultural and food chemistry. 2007 Nov; 55(23):9470-8. doi: 10.1021/jf071953k. [PMID: 17939735]
  • Birgit Benedek, Brigitte Kopp, Matthias F Melzig. Achillea millefolium L. s.l. -- is the anti-inflammatory activity mediated by protease inhibition?. Journal of ethnopharmacology. 2007 Sep; 113(2):312-7. doi: 10.1016/j.jep.2007.06.014. [PMID: 17689902]
  • Prasoon Gupta, Dinesh Kumar Yadav, Kiran Babu Siripurapu, Guatam Palit, Rakesh Maurya. Constituents of Ocimum sanctum with antistress activity. Journal of natural products. 2007 Sep; 70(9):1410-6. doi: 10.1021/np0700164. [PMID: 17850106]
  • Xia Wu, Jing Liu, Zhi-Bin Yu, Yun-Hua Ye, Ya-Wei Zhou. [Studies on flavones in of Lavandula augustifolia]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2007 May; 32(9):821-3. doi: ". [PMID: 17639984]
  • G Innocenti, E Vegeto, S Dall'Acqua, P Ciana, M Giorgetti, E Agradi, A Sozzi, G Fico, F Tomè. In vitro estrogenic activity of Achillea millefolium L. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2007 Feb; 14(2-3):147-52. doi: 10.1016/j.phymed.2006.05.005. [PMID: 16860978]
  • R Japón-Luján, M D Luque de Castro. Superheated liquid extraction of oleuropein and related biophenols from olive leaves. Journal of chromatography. A. 2006 Dec; 1136(2):185-91. doi: 10.1016/j.chroma.2006.09.081. [PMID: 17045596]
  • Dong-bao Zhao, Wei Zhang, Ming-jing Li, Xiu-hua Liu. [Studies on chemical constituents of Acroptilon repens]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 Nov; 31(22):1869-72. doi: . [PMID: 17285986]
  • Bi-Bo Hu, Zu-Shuai Wu, Jun Cai, Hui-Di Jiang. [Determination of main flavone glycosides in Flos Chrysanthemi and observation of factors influenced contents]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 Nov; 31(21):1772-5. doi: ". [PMID: 17260789]
  • Stefan Schwaiger, Christoph Seger, Bettina Wiesbauer, Peter Schneider, Ernst P Ellmerer, Sonja Sturm, Hermann Stuppner. Development of an HPLC-PAD-MS assay for the identification and quantification of major phenolic edelweiss (Leontopodium alpium Cass.) constituents. Phytochemical analysis : PCA. 2006 Sep; 17(5):291-8. doi: 10.1002/pca.917. [PMID: 17019930]
  • Yi-Nan Zheng, Jing Zhang, Li-Kun Han, Keizo Sekiya, Yoshiyuki Kimura, Hiromichi Okuda. Effects of compounds in leaves of Salix matsudana on arachidonic acid metabolism. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2005 Dec; 125(12):1005-8. doi: 10.1248/yakushi.125.1005. [PMID: 16327246]
  • Fernando Calzada. Additional antiprotozoal constituents from Cuphea pinetorum, a plant used in Mayan traditional medicine to treat diarrhoea. Phytotherapy research : PTR. 2005 Aug; 19(8):725-7. doi: 10.1002/ptr.1717. [PMID: 16177979]
  • Xueliang Fang, Lei Shao, Hui Zhang, Shaomeng Wang. CHMIS-C: a comprehensive herbal medicine information system for cancer. Journal of medicinal chemistry. 2005 Mar; 48(5):1481-8. doi: 10.1021/jm049838d. [PMID: 15743190]
  • Qiu-Sheng Zheng, Xi-Ling Sun, Bo Xu, Gang Li, Meng Song. Mechanisms of apigenin-7-glucoside as a hepatoprotective agent. Biomedical and environmental sciences : BES. 2005 Feb; 18(1):65-70. doi: . [PMID: 15861781]
  • Xianfeng Zhu, Hongxun Zhang, Raymond Lo. Phenolic compounds from the leaf extract of artichoke (Cynara scolymus L.) and their antimicrobial activities. Journal of agricultural and food chemistry. 2004 Dec; 52(24):7272-8. doi: 10.1021/jf0490192. [PMID: 15563206]
  • C S Kaiser, H Römpp, P C Schmidt. Supercritical carbon dioxide extraction of chamomile flowers: extraction efficiency, stability, and in-line inclusion of chamomile-carbon dioxide extract in beta-cyclodextrin. Phytochemical analysis : PCA. 2004 Jul; 15(4):249-56. doi: 10.1002/pca.775. [PMID: 15311845]
  • Jin Hui Kim, Young Ho Cho, Sung Min Park, Kyung Eun Lee, Jeong Jae Lee, Bum Chun Lee, Hyeong Bae Pyo, Kyung Sik Song, Hum Dai Park, Yeo Pyo Yun. Antioxidants and inhibitor of matrix metalloproteinase-1 expression from leaves of Zostera marina L. Archives of pharmacal research. 2004 Feb; 27(2):177-83. doi: 10.1007/bf02980103. [PMID: 15022719]
  • Zhen-Dan He, Kit-Man Lau, Paul Pui-Hay But, Ren-Wang Jiang, Hui Dong, Shuang-Cheng Ma, Kwok-Pui Fung, Wen-Cai Ye, Han-Dong Sun. Antioxidative glycosides from the leaves of Ligustrum robustum. Journal of natural products. 2003 Jun; 66(6):851-4. doi: 10.1021/np020568g. [PMID: 12828473]
  • Xuehui Zhang, Minqian Yu, Jianmin Chen. Simultaneous determination of seven compounds in snow lotus herb using high-performance liquid chromatography. Journal of chromatographic science. 2003 May; 41(5):241-4. doi: 10.1093/chromsci/41.5.241. [PMID: 12841951]
  • Yao-Haur Kuo, Shy-Yuan Hwang, Li-Ming Yang Kuo, Yi-Ling Lee, Shyh-Yuan Li, Ya-Ching Shen. A novel cytotoxic C-methylated biflavone, taiwanhomoflavone-B from the twigs of Cephalotaxus wilsoniana. Chemical & pharmaceutical bulletin. 2002 Dec; 50(12):1607-8. doi: 10.1248/cpb.50.1607. [PMID: 12499600]
  • Luis Góngora, Salvador Máñez, Rosa M Giner, M Carmen Recio, Alexander I Gray, José Luis Ríos. Phenolic glycosides from Phagnalon rupestre. Phytochemistry. 2002 Apr; 59(8):857-60. doi: 10.1016/s0031-9422(02)00011-0. [PMID: 11937166]
  • J Zhang, Y N Zhang, L K Han. [Studies on chemical constituents of leaves of Salix matsudana Koidz and their influence on lipolysis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2000 Sep; 25(9):538-41. doi: ". [PMID: 12516463]
  • I Aljancić, V Vajs, N Menković, I Karadzić, N Juranić, S Milosavljević, S Macura. Flavones and sesquiterpene lactones from Achillea atrata subsp. multifida: antimicrobial activity. Journal of natural products. 1999 Jun; 62(6):909-11. doi: 10.1021/np980536m. [PMID: 10395518]
  • J Zhang, Y Zheng, L Han. [Isolation of resisting thrombus and arteriosclerosis compounds in leaves of Salix matsudana]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 1999 Mar; 22(3):131-3. doi: ". [PMID: 12575095]
  • K Cimanga, T De Bruyne, A Lasure, B Van Poel, L Pieters, D Vanden Berghe, A Vlietinck, K Kambu, L Tona. In vitro anticomplementary activity of constituents from Morinda morindoides. Journal of natural products. 1995 Mar; 58(3):372-8. doi: 10.1021/np50117a005. [PMID: 7775983]
  • C Q Hu, K Chen, Q Shi, R E Kilkuskie, Y C Cheng, K H Lee. Anti-AIDS agents, 10. Acacetin-7-O-beta-D-galactopyranoside, an anti-HIV principle from Chrysanthemum morifolium and a structure-activity correlation with some related flavonoids. Journal of natural products. 1994 Jan; 57(1):42-51. doi: 10.1021/np50103a006. [PMID: 8158164]
  • K Tschiersch, J Hölzl. [Absorption and excretion of apigenin, apigenin-7-glycoside and herniarin after oral administration of extracts of Matricaria recutita (L.) (syn. Chamomilla recutita (L.) Rauschert)]. Die Pharmazie. 1993 Jul; 48(7):554-5. doi: NULL. [PMID: 8415854]