Luteolin 7-glucoside (BioDeep_00000000277)

 

Secondary id: BioDeep_00000035636, BioDeep_00000270474, BioDeep_00000345564, BioDeep_00000398502, BioDeep_00000400280, BioDeep_00000859295

natural product human metabolite PANOMIX_OTCML-2023 Antitumor activity


代谢物信息卡片


2-(3,4-dihydroxyphenyl)-5-hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

化学式: C21H20O11 (448.1006)
中文名称: 木犀草素葡萄糖甙, 木犀草苷, 青兰苷, 木樨草苷
谱图信息: 最多检出来源 Viridiplantae(plant) 22.44%

Reviewed

Last reviewed on 2024-07-09.

Cite this Page

Luteolin 7-glucoside. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/luteolin_7-glucoside (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000000277). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1(O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)C=C2OC(C3C=CC(O)=C(O)C=3)=CC(=O)C2=C(O)C=1
InChI: InChI=1/C21H20O11/c22-7-16-18(27)19(28)20(29)21(32-16)30-9-4-12(25)17-13(26)6-14(31-15(17)5-9)8-1-2-10(23)11(24)3-8/h1-6,16,18-25,27-29H,7H2/t16-,18-,19+,20-,21-/m1/s1

描述信息

Luteolin 7-O-beta-D-glucoside is a glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an antioxidant and a plant metabolite. It is a beta-D-glucoside, a glycosyloxyflavone, a trihydroxyflavone and a monosaccharide derivative. It is functionally related to a luteolin. It is a conjugate acid of a luteolin 7-O-beta-D-glucoside(1-).
Cynaroside is a natural product found in Verbascum lychnitis, Carex fraseriana, and other organisms with data available.
See also: Cynara scolymus leaf (part of); Lonicera japonica flower (part of); Chamaemelum nobile flower (part of).
Luteolin 7-glucoside is found in anise. Luteolin 7-glucoside is a constituent of the leaves of Capsicum annuum (red pepper).Cynaroside is a flavone, a flavonoid-like chemical compound. It is a 7-O-glucoside of luteolin and can be found in dandelion coffee, in Ferula varia and F. foetida in Campanula persicifolia and C. rotundifolia and in Cynara scolymus (artichoke)
A glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
Constituent of the leaves of Capsicum annuum (red pepper)
Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 32 nM. Cynaroside also is a promising inhibitor for H2O2-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities[1][3][4][5].

同义名列表

109 个代谢物同义名

2-(3,4-dihydroxyphenyl)-5-hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-, mono-beta-D-glucopyranoside; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one mono-beta-D-glucopyranoside; 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-5-hydroxy-; 2-(3,4-DIHYDROXYPHENYL)-7-(.BETA.-D-GLUCOPYRANOSYLOXY)-5-HYDROXY-4H-1-BENZOPYRAN-4-ONE; 2-(3,4-Dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-7-(b-D-glucopyranosyloxy)-5-hydroxy-; 2-(3,4-Dihydroxyphenyl)-7-(b-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-one; 2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-one; 7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside; 2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-yl b-D-glucopyranoside; 2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-yl β-D-glucopyranoside; Luteolin 7-O-Glucoside, United States Pharmacopeia (USP) Reference Standard; 2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-yl hexopyranoside #; Luteolin 7-glucoside, primary pharmaceutical reference standard; Flavone, 3,4,5,7-tetrahydroxy-, mono-beta-D-glucopyranoside; 3,4,5,7-TETRAHYDROXYFLAVONE 7-.BETA.-D-GLUCOPYRANOSIDE; 3,4,5,7-TETRAHYDROXYFLAVONE 7-beta-D-GLUCOPYRANOSIDE; 3,4,5-TRIHYDROXYFLAVONE 7-O-.BETA.-D-GLUCOPYRANOSIDE; 3’,4’,5,7-Tetrahydroxyflavone 7-β-D-glucopyranoside; 3,4,5-TRIHYDROXYFLAVONE 7-O-beta-D-GLUCOPYRANOSIDE; 3,4,5,7-Tetrahydroxyflavone 7-β-D-glucopyranoside; 3’,4’,5-Trihydroxyflavone 7-O-β-D-glucopyranoside; Luteolin-7-O-glucoside 1000 microg/mL in Ethanol; 7-(.BETA.-D-GLUCOSYLOXY)-3,4,5-TRIHYDROXYFLAVONE; 7-O-beta-D-Glucosyl-5,7,3,4-tetrahydroxyflavone; 3,4,5-Trihydroxyflavone 7-O-β-D-glucopyranoside; 7-(beta-D-GLUCOSYLOXY)-3,4,5-TRIHYDROXYFLAVONE; Luteolin 7-O-beta-D-glucoside, >=98.0\\% (HPLC); Luteolin 7-glucoside;Luteolin 7-O--D-glucoside; 7-(β-D-Glucosyloxy)-3’,4’,5-trihydroxyflavone; 7-O-Β-D-glucosyl-5,7,3,4-tetrahydroxyflavone; 7-O-b-D-Glucosyl-5,7,3,4-tetrahydroxyflavone; 7-(β-D-Glucosyloxy)-3,4,5-trihydroxyflavone; Luteolin 7-glucoside, analytical standard; Flavon, 3,4,5,7-tetrahydroxy-, glucoside; LUTEOLIN 7-O-.BETA.-D-GLUCOPYRANOSIDE; LUTEOLIN, 7-.BETA.-D-GLUCOPYRANOSIDE; LUTEOLIN 5-O-.BETA.-GLUCOPYRANOSIDE; LUTEOLIN-7-O-4C1-.BETA.-D-GLUCOSIDE; Luteolin 7-.beta.-D-glucopyranoside; LUTEOLIN 7-O-.BETA.-GLUCOPYRANOSIDE; luteolin 7-O-beta-d-glucopyranoside; luteolin-7-O-beta-D-glucopyranoside; LUTEOLIN, 7-beta-D-GLUCOPYRANOSIDE; LUTEOLIN 7-O-beta-GLUCOPYRANOSIDE; LUTEOLIN 5-O-beta-GLUCOPYRANOSIDE; LUTEOLIN-7-O-4C1-beta-D-GLUCOSIDE; Luteolin 7-O-β-D-glucopyranoside; LUTEOLIN 7-O-GLUCOSIDE [USP-RS]; LUTEOLIN 7-O-.BETA.-D-GLUCOSIDE; LUTEOLIN 7-O-GLUCOSIDE (USP-RS); Luteolin 7-O-β-glucopyranoside; Luteolin-7-O-D-glucopyranoside; Luteolin 7-b-D-Glucopyranoside; Luteolin 7-.beta.-D-glucoside; Luteolin 7-O-beta-D-glucoside; LUTEOLIN 7-O-.BETA.-GLUCOSIDE; Luteolin 7-O-glucopyranoside; Luteolin-7-D-glucopyranoside; Luteolin-7-O-Glucoside ,(S); 7-.BETA.-D-GLUCOSYLLUTEOLIN; luteolin-7-beta-D-glucoside; luteolin-7-O-beta-glucoside; 7-O-beta-D-Glucosylluteolin; PEFNSGRTCBGNAN-QNDFHXLGSA-N; LUTEOLIN 7-O-beta-GLUCOSIDE; Luteolin 7-beta-D-glucoside; Luteolin 7-O-b-D-glucoside; luteolin-7-O-monoglucoside; Luteolin 7-O-β-D-glucoside; LUTEOLIN 7-GLUCOSIDE [MI]; Luteolin 7-beta-glucoside; 7-beta-D-GLUCOSYLLUTEOLIN; Luteolin 7-O-D-glucoside; Luteolin 7-β-D-glucoside; Luteolin 7-monoglucoside; Luteolin 7-O-β-glucoside; 7-O-β-D-Glucosylluteolin; Luteolin 7-O-glucoside; luteolin-7-O-glucoside; Luteolin monoglucoside; luteolin-7-glucoside; Luteolin 7-glucoside; Daphneflavonoloside; Luteolin, glucoside; luteolin glucoside; 7-Glucosylluteolin; 7-Glucoluteolin; UNII-98J6XDS46I; Flavopurposide; Glucoluteolin; MEGxp0_000619; nephrocizine; luteoloside; nephrocizin; cinaroside; galuteolin; Cynaroside; 98J6XDS46I; 7-O-β-D-Glucosyl-5,7,3,4-tetrahydroxyflavone; Luteolin 7-O-β-D-glucoside; Luteolin 7-O-beta-D-glucoside



数据库引用编号

46 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

26 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(24)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

547 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 14 AIMP2, AKT1, BCL2, CASP3, CAT, MAPK8, MTOR, NFE2L2, NLRP3, NOS2, PIK3CA, PTGS2, STAT3, TLR4
Peripheral membrane protein 3 ACHE, MTOR, PTGS2
Endosome membrane 1 TLR4
Endoplasmic reticulum membrane 4 BCL2, HMOX1, MTOR, PTGS2
Nucleus 12 ACHE, AIMP2, AKT1, BCL2, CASP3, HMOX1, MAPK8, MTOR, NFE2L2, NLRP3, NOS2, STAT3
cytosol 13 AIMP2, AKT1, BCL2, CASP3, CAT, HMOX1, MAPK8, MTOR, NFE2L2, NLRP3, NOS2, PIK3CA, STAT3
dendrite 1 MTOR
phagocytic vesicle 1 MTOR
centrosome 1 NFE2L2
nucleoplasm 8 AKT1, CASP3, HMOX1, MAPK8, MTOR, NFE2L2, NOS2, STAT3
RNA polymerase II transcription regulator complex 2 NFE2L2, STAT3
Cell membrane 4 ACHE, AKT1, TLR4, TNF
Cytoplasmic side 2 HMOX1, MTOR
lamellipodium 2 AKT1, PIK3CA
Golgi apparatus membrane 2 MTOR, NLRP3
Synapse 2 ACHE, MAPK8
cell cortex 1 AKT1
cell surface 3 ACHE, TLR4, TNF
glutamatergic synapse 2 AKT1, CASP3
Golgi apparatus 2 ACHE, NFE2L2
Golgi membrane 3 INS, MTOR, NLRP3
lysosomal membrane 2 GAA, MTOR
neuromuscular junction 1 ACHE
neuronal cell body 2 CASP3, TNF
postsynapse 1 AKT1
Cytoplasm, cytosol 4 AIMP2, NFE2L2, NLRP3, NOS2
Lysosome 2 GAA, MTOR
plasma membrane 9 ACHE, AKT1, GAA, NFE2L2, NOS2, PIK3CA, STAT3, TLR4, TNF
Membrane 10 ACHE, AIMP2, AKT1, BCL2, CAT, GAA, HMOX1, MTOR, NLRP3, TLR4
axon 1 MAPK8
caveola 1 PTGS2
extracellular exosome 2 CAT, GAA
Lysosome membrane 2 GAA, MTOR
endoplasmic reticulum 4 BCL2, HMOX1, NLRP3, PTGS2
extracellular space 5 ACHE, HMOX1, IL6, INS, TNF
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 5 ACHE, HMOX1, NOS2, PIK3CA, TLR4
intercalated disc 1 PIK3CA
mitochondrion 3 BCL2, CAT, NLRP3
protein-containing complex 4 AKT1, BCL2, CAT, PTGS2
intracellular membrane-bounded organelle 2 CAT, GAA
Microsome membrane 2 MTOR, PTGS2
postsynaptic density 1 CASP3
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 TLR4
Secreted 5 ACHE, GAA, IL6, INS, NLRP3
extracellular region 7 ACHE, CAT, GAA, IL6, INS, NLRP3, TNF
Mitochondrion outer membrane 2 BCL2, MTOR
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 3 BCL2, HMOX1, MTOR
mitochondrial matrix 1 CAT
Extracellular side 1 ACHE
transcription regulator complex 1 STAT3
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 2 TLR4, TNF
microtubule cytoskeleton 1 AKT1
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
Early endosome 1 TLR4
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Cytoplasm, perinuclear region 1 NOS2
Membrane raft 1 TNF
pore complex 1 BCL2
focal adhesion 1 CAT
spindle 1 AKT1
Peroxisome 2 CAT, NOS2
basement membrane 1 ACHE
Peroxisome matrix 1 CAT
peroxisomal matrix 2 CAT, NOS2
peroxisomal membrane 1 CAT
Nucleus, PML body 1 MTOR
PML body 1 MTOR
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
Cytoplasm, cytoskeleton, microtubule organizing center 1 NLRP3
Inflammasome 1 NLRP3
interphase microtubule organizing center 1 NLRP3
NLRP3 inflammasome complex 1 NLRP3
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 1 TLR4
neuron projection 1 PTGS2
ciliary basal body 1 AKT1
chromatin 2 NFE2L2, STAT3
mediator complex 1 NFE2L2
phagocytic cup 2 TLR4, TNF
Lipid-anchor, GPI-anchor 1 ACHE
nuclear envelope 1 MTOR
Endomembrane system 2 MTOR, NLRP3
endosome lumen 1 INS
microtubule organizing center 1 NLRP3
tertiary granule membrane 1 GAA
side of membrane 1 ACHE
myelin sheath 1 BCL2
lipopolysaccharide receptor complex 1 TLR4
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 IL6, INS, PTGS2
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
transport vesicle 1 INS
azurophil granule membrane 1 GAA
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Single-pass type IV membrane protein 1 HMOX1
synaptic cleft 1 ACHE
protein-DNA complex 1 NFE2L2
ficolin-1-rich granule membrane 1 GAA
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
aminoacyl-tRNA synthetase multienzyme complex 1 AIMP2
Cytoplasmic vesicle, phagosome 1 MTOR
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
cortical cytoskeleton 1 NOS2
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
autolysosome lumen 1 GAA
BAD-BCL-2 complex 1 BCL2
[Isoform H]: Cell membrane 1 ACHE
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Yiwei Zhou, Yuhan Huang, Wei Ye, Zijie Chen, Zhengzhong Yuan. Cynaroside improved depressive-like behavior in CUMS mice by suppressing microglial inflammation and ferroptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 Apr; 173(?):116425. doi: 10.1016/j.biopha.2024.116425. [PMID: 38490155]
  • Sahar Saleh Alghamdi, Sara Abdulaziz Alghashem, Rizwan Ali, Arwa Alsubait, Rasha Saad Suliman, Afrah E Mohammed, Zeyad Alehaideb, Raghad Abdullah Alshafi, Allulu Yousef Alturki, Ishrat Rahman. Exploring the potential of Ziziphus nummularia and luteolin-7-O-glucoside as tubulin inhibitors in cancer therapy and survival. Scientific reports. 2024 03; 14(1):7202. doi: 10.1038/s41598-024-57680-0. [PMID: 38531974]
  • Taghreed A Majrashi, Mahmoud A El Hassab, Sara H Mahmoud, Ahmed Mostafa, Engy A Wahsh, Eslam B Elkaeed, Fatma E Hassan, Wagdy M Eldehna, Shimaa M Abdelgawad. In vitro biological evaluation and in silico insights into the antiviral activity of standardized olive leaves extract against SARS-CoV-2. PloS one. 2024; 19(4):e0301086. doi: 10.1371/journal.pone.0301086. [PMID: 38662719]
  • Lucia Camelia Pirvu, Lucia Pintilie, Adrian Albulescu, Amalia Stefaniu, Georgeta Neagu. Anti-Proliferative Potential of Cynaroside and Orientin-In Silico (DYRK2) and In Vitro (U87 and Caco-2) Studies. International journal of molecular sciences. 2023 Nov; 24(23):. doi: 10.3390/ijms242316555. [PMID: 38068880]
  • Abdelhakim Bouyahya, Douae Taha, Taoufiq Benali, Gokhan Zengin, Nasreddine El Omari, Naoufal El Hachlafi, Asaad Khalid, Ashraf N Abdalla, Chrismawan Ardianto, Ching Siang Tan, Long Chiau Ming, Narjis Sahib. Natural sources, biological effects, and pharmacological properties of cynaroside. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Feb; 161(?):114337. doi: 10.1016/j.biopha.2023.114337. [PMID: 36812715]
  • Sezen Yılmaz Sarıaltın, Özlem Bahadır Acıkara. Assessment of Correlation Analysis, Phytochemical Profile, and Biological Activities of Endemic Scorzonera Species from Turkey. Chemistry & biodiversity. 2022 Oct; 19(10):e202200007. doi: 10.1002/cbdv.202200007. [PMID: 36031843]
  • Gabin Thierry M Bitchagno, Anja Schüffler, Jonathan Gross, Matthias Krumb, Pierre Tane, Till Opatz. Sesquiterpene Lactones from Vernonia tufnelliae: Structural Characterization and Biological Evaluation. Journal of natural products. 2022 07; 85(7):1681-1690. doi: 10.1021/acs.jnatprod.2c00055. [PMID: 35704432]
  • Shu-Ping Chen, Tian-Hong Hu, Qing Zhou, Tian-Peng Chen, Dong Yin, Huan He, Qing Huang, Ming He. Luteoloside protects the vascular endothelium against iron overload injury via the ROS/ADMA/DDAH II/eNOS/NO pathway. Chinese journal of natural medicines. 2022 Jan; 20(1):22-32. doi: 10.1016/s1875-5364(21)60110-3. [PMID: 35101247]
  • Aboli Girme, Prajkta Bhoj, Ganesh Saste, Sandeep Pawar, Amit Mirgal, Dipak Raut, Machindra Chavan, Lal Hingorani. Development and Validation of RP-HPLC Method for Vicenin-2, Orientin, Cynaroside, Betulinic Acid, Genistein, and Major Eight Bioactive Constituents with LC-ESI-MS/MS Profiling in Ocimum Genus. Journal of AOAC International. 2021 Dec; 104(6):1634-1651. doi: 10.1093/jaoacint/qsab067. [PMID: 33930142]
  • Juanli Ji, Zhongze Wang, Wei Sun, Zekun Li, Huarui Cai, Erhu Zhao, Hongjuan Cui. Effects of Cynaroside on Cell Proliferation, Apoptosis, Migration and Invasion though the MET/AKT/mTOR Axis in Gastric Cancer. International journal of molecular sciences. 2021 Nov; 22(22):. doi: 10.3390/ijms222212125. [PMID: 34830011]
  • Bruno César Correa Salles, Krissia Caroline Leme, Marcelo Aparecido da Silva, Cláudia Quintino da Rocha, Marcelo M P Tangerina, Wagner Vilegas, Sônia A Figueiredo, Stella Maris da Silveira Duarte, Maria Rita Rodrigues, Fernanda Borges de Araújo Paula. Protective effect of flavonoids from Passiflora edulis Sims on diabetic complications in rats. The Journal of pharmacy and pharmacology. 2021 Sep; 73(10):1361-1368. doi: 10.1093/jpp/rgab046. [PMID: 33772554]
  • Zheng Wang, Wen Chen, Yunying Li, Shuying Zhang, He Lou, Xiaoyan Lu, Xiaohui Fan. Reduning injection and its effective constituent luteoloside protect against sepsis partly via inhibition of HMGB1/TLR4/NF-κB/MAPKs signaling pathways. Journal of ethnopharmacology. 2021 Apr; 270(?):113783. doi: 10.1016/j.jep.2021.113783. [PMID: 33421596]
  • Jun Gu Kim, Jin Woo Lee, Thi Phuong Linh Le, Jae Sang Han, Yong Beom Cho, Haeun Kwon, Dongho Lee, Mi Kyeong Lee, Bang Yeon Hwang. Sesquiterpenoids from Chrysanthemum indicum with Inhibitory Effects on NO Production. Journal of natural products. 2021 03; 84(3):562-569. doi: 10.1021/acs.jnatprod.0c01121. [PMID: 33667099]
  • Alessandro De Stefano, Sabrina Caporali, Nicola Di Daniele, Valentina Rovella, Carmine Cardillo, Francesca Schinzari, Marilena Minieri, Massimo Pieri, Eleonora Candi, Sergio Bernardini, Manfredi Tesauro, Alessandro Terrinoni. Anti-Inflammatory and Proliferative Properties of Luteolin-7-O-Glucoside. International journal of molecular sciences. 2021 Jan; 22(3):. doi: 10.3390/ijms22031321. [PMID: 33525692]
  • Stefania Monari, Maura Ferri, Beatrice Montecchi, Mirko Salinitro, Annalisa Tassoni. Phytochemical characterization of raw and cooked traditionally consumed alimurgic plants. PloS one. 2021; 16(8):e0256703. doi: 10.1371/journal.pone.0256703. [PMID: 34437649]
  • Eui Jeong Nam, Gyhye Yoo, Joo Young Lee, Myungsuk Kim, Changho Jhin, Yang-Ju Son, Sun Young Kim, Sang Hoon Jung, Chu Won Nho. Glycosyl flavones from Humulus japonicus suppress MMP-1 production via decreasing oxidative stress in UVB irradiated human dermal fibroblasts. BMB reports. 2020 Jul; 53(7):379-384. doi: . [PMID: 32317077]
  • Saied Goodarzi, Mir Javad Tabatabaei, Razieh Mohammad Jafari, Farzaneh Shemirani, Saeed Tavakoli, Mansur Mofasseri, Zahra Tofighi. Cuminum cyminum fruits as source of luteolin- 7-O-glucoside, potent cytotoxic flavonoid against breast cancer cell lines. Natural product research. 2020 Jun; 34(11):1602-1606. doi: 10.1080/14786419.2018.1519824. [PMID: 30580606]
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