L-Isoleucine (BioDeep_00000000784)

 

Secondary id: BioDeep_00000229676, BioDeep_00000398133, BioDeep_00000399868

natural product human metabolite PANOMIX_OTCML-2023 blood metabolite BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


(2S,3S)-2-amino-3-methylpentanoic acid

化学式: C6H13NO2 (131.0946238)
中文名称: DL-异亮氨酸, L-异亮氨酸, DL-别异亮氨酸, 异亮氨酸, L-异白氨酸, l-异亮氨酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.03%

Reviewed

Last reviewed on 2024-07-01.

Cite this Page

L-Isoleucine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/l-isoleucine (retrieved 2024-11-22) (BioDeep RN: BioDeep_00000000784). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C([C@@H](N)[C@@H](C)CC)(=O)O
InChI: InChI=1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)

描述信息

Isoleucine (Ile) or L-isoleucine is an alpha-amino acid. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). Amino acids are organic compounds that contain amino (–NH2) and carboxyl (–COOH) functional groups, along with a side chain (R group) specific to each amino acid. L-isolecuine is one of 20 proteinogenic amino acids, i.e., the amino acids used in the biosynthesis of proteins. Isoleucine is found in all organisms ranging from bacteria to plants to animals. It is classified as a non-polar, uncharged (at physiological pH) aliphatic amino acid. Isoleucine is an essential amino acid in humans, meaning the body cannot synthesize it and that it must be obtained from the diet. In plants and microorganisms, isoleucine is synthesized starting from pyruvate and alpha-ketobutyrate. Isoleucine is classified as a branched chain amino acid (BCAA). BCAAs include three amino acids: isoleucine, leucine and valine. They are alpha amino acids whose carbon structure is marked by a beta branch point. Despite their structural similarities, BCAAs have different metabolic routes, with valine going solely to carbohydrates (glucogenic), leucine solely to fats (ketogenic) and isoleucine being both a glucogenic and a ketogenic amino acid. Isoleucine is catabolized via with alpha-ketoglutarate where upon it is oxidized and split into propionyl-CoA and acetyl-CoA. Propionyl-CoA is converted into succinyl-CoA, a TCA cycle intermediate which can be converted into oxaloacetate for gluconeogenesis (hence glucogenic). The acetyl-CoA can be fed into the TCA cycle by condensing with oxaloacetate to form citrate or used in the synthesis of ketone bodies or fatty acids. The different metabolism of BCAAs accounts for different requirements for these essential amino acids in humans: 12 mg/kg, 14 mg/kg and 16 mg/kg of valine, leucine and isoleucine are required respectively. Furthermore, these amino acids have different deficiency symptoms. Valine deficiency is marked by neurological defects in the brain, while isoleucine deficiency is marked by muscle tremors. BCAAs are decreased in patients with liver disease, such as hepatitis, hepatic coma, cirrhosis, extrahepatic biliary atresia. An inability to break down isoleucine, along with other amino acids, is associated with maple syrup urine disease (MSUD) (PMID: 34125801). Isoleucine, like other BCAAs, is associated with insulin resistance. In particular, higher levels of isoleucine are observed in the blood of diabetic mice, rats, and humans (PMID 25287287). Mice fed an isoleucine deprivation diet for one day have improved insulin sensitivity, and feeding of an isoleucine deprivation diet for one week significantly decreases blood glucose levels (PMID: 24684822).
L-isoleucine is the L-enantiomer of isoleucine. It has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. It is an aspartate family amino acid, a proteinogenic amino acid, an isoleucine and a L-alpha-amino acid. It is a conjugate base of a L-isoleucinium. It is a conjugate acid of a L-isoleucinate. It is an enantiomer of a D-isoleucine. It is a tautomer of a L-isoleucine zwitterion.
An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of leucine. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.
L-Isoleucine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Isoleucine is one of nine essential amino acids in humans (present in dietary proteins), Isoleucine has diverse physiological functions, such as assisting wound healing, detoxification of nitrogenous wastes, stimulating immune function, and promoting secretion of several hormones. Necessary for hemoglobin formation and regulating blood sugar and energy levels, isoleucine is concentrated in muscle tissues in humans. Isoleucine is found especially in meats, fish, cheese, eggs, and most seeds and nuts. (NCI04)
L-Isoleucine is one of the essential amino acids that cannot be made by the body and is known for its ability to help endurance and assist in the repair and rebuilding of muscle. This amino acid is important to body builders as it helps boost energy and helps the body recover from training. L-Isoleucine is also classified as a branched-chain amino acid (BCAA). It helps promote muscle recovery after exercise. Isoleucine is actually broken down for energy within the muscle tissue. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.
An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of LEUCINE. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.

L-Isoleucine. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=73-32-5 (retrieved 2024-07-01) (CAS RN: 73-32-5). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.
L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.

同义名列表

138 个代谢物同义名

L-Isoleucine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0\\%; (S,S)-2-amino-3-methyl-pentanoicacid;(s,s)-isoleucine;[S-(R*,R*)]-2-Amino-3-methylpentanoic acid; L-Isoleucine, Pharmaceutical Secondary Standard; Certified Reference Material; 6-?amino-?5-?(ethylamino)?-?1-?methyl-2,?4(1H,?3H)?-?Pyrimidinedione; L-Isoleucine, United States Pharmacopeia (USP) Reference Standard; Isoleucine, European Pharmacopoeia (EP) Reference Standard; L-Isoleucine, certified reference material, TraceCERT(R); (2S,3S)-.alpha.-Amino-.beta.-methyl-n-valeric acid; .alpha.-Amino-.beta.-methylvaleric acid, (2S,3S)-; Pentanoic acid, 2-amino-3-methyl-, [S-(R*,R*)]-; L-Isoleucine, Cell Culture Reagent (H-L-Ile-OH); (2S,3S)-alpha-Amino-beta-merthyl-n-valeric acid; (2S,3S)-alpha-Amino-beta-methyl-n-valeric acid; Pentanoic acid, 2-amino-3-methyl-, (S-(R*,R))-; L-Isoleucine, Vetec(TM) reagent grade, >=98\\%; Acetic acid, amino(1-methylpropyl)-, (R*,R*)-; 2-Amino-3-methylpentanoic acid, (S-(R*,R*))-; (2S,3S)-alpha-Amino-beta-merthylvaleric acid; (+/-)-erythro-2-Amino-3-methylpentanoic acid; (2S,3S)-alpha-Amino-beta-merthyl-n-valerate; (2S,3S)-alpha-Amino-beta-methylvaleric acid; Pentanoic acid, 2-amino-3-methyl-, (2S,3S)-; (2S,3S)-alph-Amino-beta-methylvaleric acid; (2S,3S)-alpha-Amino-beta-methyl-n-valerate; L-Isoleucine, reagent grade, >=98\\% (HPLC); [S-(R*,R*)]-2-Amino-3-methylpentanoic acid; (S-(R*,R*))-2-Amino-3-methylpentanoic acid; L-Isoleucine, SAJ special grade, >=99.0\\%; (2S,3S)-alpha-Amino-beta-merthylvalerate; (2S,3S)-alpha-Amino-beta-methylvalerate; (2S,3S)-a-Amino-b-methyl-n-valeric acid; (2S,3S)-2-amino-3-methyl-Pentanoic acid; (2S,3S)-alph-Amino-beta-methylvalerate; (2S,3S)-2-Amino-3-methylpentanoic acid; [S-(R*,R*)]-2-Amino-3-methylpentanoate; (2S,3S)-2-Amino-3-methylpentanoicacid; L-Isoleucine, BioUltra, >=99.5\\% (NT); (2S,3S)-a-Amino-b-methylvaleric acid; (2S,3S)-2-amino-3-methyl-Pentanoate; (2S,3S)-a-Amino-b-methyl-n-valerate; alpha-Amino-beta-methylvaleric acid; (2S,3S)-2-amino-3-methylpentanoate; Pentanoic acid, 2-amino-3-methyl-; (2S,3S)-a-Amino-b-methylvalerate; LEUCINE IMPURITY A [EP IMPURITY]; L-Norvaline, 3-methyl-, erythro-; 2S-Amino-3S-methylpentanoic acid; L-Isoleucine, Vetec(TM), 98.5\\%; VALINE IMPURITY B [EP IMPURITY]; L-Isoleucine: D-allo-isoleucine; Valeric acid, 2-amino-3-methyl-; alpha-Amino-beta-methylvalerate; 2-Amino-3-methylpentanoic acid; Norvaline, 3-methyl-, erythro-; Acetic acid, amino-sec-butyl-; Isoleucine [USAN:USP:INN:BAN]; 2-Amino-3-methylvaleric acid; a-Amino-b-methylvaleric acid; Α-amino-β-methylvaleric acid; 2S-Amino-3S-methylpentanoate; L-Isoleucine, 99\\%, FCC, FG; ISOLEUCINE [USP MONOGRAPH]; 2-amino-3-methylpentanoate; Isoleucine (L-Isoleucine); ISOLEUCINE [EP MONOGRAPH]; L-Isoleucine (H-L-Ile-OH); Α-amino-β-methylvalerate; 2-Amino-3-methylvalerate; a-Amino-b-methylvalerate; ISOLEUCINE DL-FORM [MI]; L-Isoleucine (H-lle-OH); Isoleucine [USAN:INN]; L-ISOLEUCINE [USP-RS]; Isoleucine, L Isomer; DL-ISOLEUCINE [FHFI]; Isoleucine, L-Isomer; Isoleucine, L- (8CI); Isoleucina [Spanish]; Norvaline, 3-methyl-; erythro-L-Isoleucine; sec-C4H9CH(NH2)COOH; ISOLEUCINE [WHO-DD]; DL-ISOLEUCINE [FCC]; L-Isoleucine (JP17); Isoleucinum [Latin]; L-Isomer Isoleucine; ISOLEUCINE DL-FORM; ISOLEUCINE [VANDF]; L-ISOLEUCINE [FCC]; ISOLEUCINE [MART.]; DL-Allo-isoleucine; L-Isoleucine, 99\\%; L-ISOLEUCINE [JAN]; ISOLEUCINE [INCI]; L-[14C]Isoleucine; ISOLEUCINE [USAN]; ISOLEUCINE [HSDB]; (S,S)-Isoleucine; 2S,3S-Isoleucine; L-Isoleucine,(S); L-(+)-Isoleucine; Isoleucine (VAN); ISOLEUCINE [INN]; (+)-L-isoleucine; Isoleucine (USP); ISOLEUCINE [MI]; Isoleucine, DL-; UNII-5HX0BYT4E3; ISOLEUCINE [II]; UNII-04Y7590D77; (L)-Isoleucine; L- iso-Leucine; (S)-Isoleucine; ISOLEUCINE, L-; Alloisoleucine; Tox21_112765_1; L-iso-leucine; DL-Isoleucine; Tox21_112765; L-lsoleucine; L-Isoleucine; iso-leucine; Isoleucinum; 5HX0BYT4E3; 04Y7590D77; Isoleucine; Isoleucina; AI3-18474; H-Ile-OH; Ile-OH; H-Ile; L-Ile; ile; I; L-Alloisoleucine; Isoleucine; L-Isoleucine; l-Isoleucine



数据库引用编号

55 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(4)

PlantCyc(0)

代谢反应

74 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(4)

WikiPathways(2)

Plant Reactome(0)

INOH(2)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(66)

PharmGKB(0)

407 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Rina Saito, Mai Morikawa, Toshiya Muto, Sayaka Saito, Takuya Kaji, Minoru Ueda. SlCYP94B18 and SlCYP94B19 monooxygenases for the catabolic turnover of jasmonates in tomato leaves. Phytochemistry. 2024 Jul; 223(?):114141. doi: 10.1016/j.phytochem.2024.114141. [PMID: 38750708]
  • Maria Ladeynova, Darya Kuznetsova, Anna Pecherina, Vladimir Vodeneev. pH change accompanying long-distance electrical signal controls systemic jasmonate biosynthesis. Journal of plant physiology. 2024 May; 296(?):154225. doi: 10.1016/j.jplph.2024.154225. [PMID: 38522214]
  • Na Song, Jinsong Wu. NaWRKY70 is a key regulator of Nicotiana attenuata resistance to Alternaria alternata through regulation of phytohormones and phytoalexins biosynthesis. The New phytologist. 2024 May; 242(3):1289-1306. doi: 10.1111/nph.19647. [PMID: 38426573]
  • Ludan Cao, Guo Wang, Xiuxu Ye, Fang Li, Shujun Wang, Huanling Li, Peng Wang, Jiabao Wang. Physiological, Metabolic, and Transcriptomic Analyses Reveal Mechanisms of Proliferation and Somatic Embryogenesis of Litchi (Litchi chinensis Sonn.) Embryogenic Callus Promoted by D-Arginine Treatment. International journal of molecular sciences. 2024 Apr; 25(7):. doi: 10.3390/ijms25073965. [PMID: 38612774]
  • Tianxia Yang, Lei Deng, Qinyang Wang, Chuanlong Sun, Muhammad Ali, Fangming Wu, Huawei Zhai, Qian Xu, Peiyong Xin, Shujing Cheng, Jinfang Chu, Tingting Huang, Chang-Bao Li, Chuanyou Li. Tomato CYP94C1 inactivates bioactive JA-Ile to attenuate jasmonate-mediated defense during fruit ripening. Molecular plant. 2024 Apr; 17(4):509-512. doi: 10.1016/j.molp.2024.02.004. [PMID: 38327053]
  • Haoming Zuo, Jiahao Chen, Zhidong Lv, Chenyu Shao, Ziqi Chen, Yuebin Zhou, Chengwen Shen. Tea-Derived Polyphenols Enhance Drought Resistance of Tea Plants (Camellia sinensis) by Alleviating Jasmonate-Isoleucine Pathway and Flavonoid Metabolism Flow. International journal of molecular sciences. 2024 Mar; 25(7):. doi: 10.3390/ijms25073817. [PMID: 38612625]
  • Shuting Chen, Miaofen Ye, Peng Kuai, Lin Chen, Yonggen Lou. Silencing an ATP-Dependent Caseinolytic Protease Proteolytic Subunit Gene Enhances the Resistance of Rice to Nilaparvata lugens. International journal of molecular sciences. 2024 Mar; 25(7):. doi: 10.3390/ijms25073699. [PMID: 38612510]
  • Yajun Gou, Yueqin Heng, Wenyan Ding, Canhong Xu, Qiushuang Tan, Yajing Li, Yudong Fang, Xiaoqing Li, Degui Zhou, Xinyu Zhu, Mingyue Zhang, Rongjian Ye, Haiyang Wang, Rongxin Shen. Natural variation in OsMYB8 confers diurnal floret opening time divergence between indica and japonica subspecies. Nature communications. 2024 Mar; 15(1):2262. doi: 10.1038/s41467-024-46579-z. [PMID: 38480732]
  • Sarathadevi Rajendran, Patrick Silcock, Phil Bremer. Volatile Organic Compounds (VOCs) Produced by Levilactobacillus brevis WLP672 Fermentation in Defined Media Supplemented with Different Amino Acids. Molecules (Basel, Switzerland). 2024 Feb; 29(4):. doi: 10.3390/molecules29040753. [PMID: 38398505]
  • Weilong Kong, Ping Zhao, Qing Zhang, Jingjing Yang, Qiufang Zhu, Yanbing Zhang, Xuming Deng, Xiao Chen, Jinke Lin, Xingtan Zhang. Chromatin accessibility mediated transcriptome changes contribute to flavor substance alterations and jasmonic acid hyperaccumulation during oolong tea withering process. The Plant journal : for cell and molecular biology. 2024 Feb; 117(3):679-693. doi: 10.1111/tpj.16521. [PMID: 37921032]
  • Deepika Mittal, Janesh Kumar Gautam, Mahendra Varma, Amrutha Laie, Shruti Mishra, Smrutisanjita Behera, Jyothilakshmi Vadassery. External jasmonic acid isoleucine mediates amplification of plant elicitor peptide receptor (PEPR) and jasmonate-based immune signalling. Plant, cell & environment. 2024 Jan; ?(?):. doi: 10.1111/pce.14812. [PMID: 38229005]
  • Hui Yang, Yan-Ru Liu, Zhong-Xing Song, Zhi-Shu Tang, Ai-Ling Jia, Ming-Geng Wang, Jin-Ao Duan. Study on the underlying mechanism of Poria in intervention of arrhythmia zebrafish by integrating metabolomics and network pharmacology. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jan; 122(?):155143. doi: 10.1016/j.phymed.2023.155143. [PMID: 37890443]
  • Ming Zeng, Franziska Krajinski, Nicole M van Dam, Bettina Hause. Jarin-1, an inhibitor of JA-Ile biosynthesis in Arabidopsis thaliana, acts differently in other plant species. Plant signaling & behavior. 2023 Dec; 18(1):2273515. doi: 10.1080/15592324.2023.2273515. [PMID: 37902262]
  • Marta Vazquez-Vilar, Asun Fernandez-Del-Carmen, Victor Garcia-Carpintero, Margit Drapal, Silvia Presa, Dorotea Ricci, Gianfranco Diretto, José Luis Rambla, Rafael Fernandez-Muñoz, Ana Espinosa-Ruiz, Paul D Fraser, Cathie Martin, Antonio Granell, Diego Orzaez. Dually biofortified cisgenic tomatoes with increased flavonoids and branched-chain amino acids content. Plant biotechnology journal. 2023 Sep; ?(?):. doi: 10.1111/pbi.14163. [PMID: 37749961]
  • Taichi Okumura, Tsumugi Kitajima, Takuya Kaji, Haruyuki Urano, Kotaro Matsumoto, Hideo Inagaki, Koji Miyamoto, Kazunori Okada, Minoru Ueda. Difference in the ligand affinity among redundant plant hormone receptors of rice OsCOI1a/1b/2-OsJAZs. Bioscience, biotechnology, and biochemistry. 2023 Sep; 87(10):1122-1128. doi: 10.1093/bbb/zbad092. [PMID: 37403366]
  • Yuli Wang, Xue Rong, Hui Guan, Fangxin Ouyang, Xing Zhou, Feng Li, Xintong Tan, Dapeng Li. The Potential Effects of Isoleucine Restricted Diet on Cognitive Impairment in High-Fat-Induced Obese Mice via Gut Microbiota-Brain Axis. Molecular nutrition & food research. 2023 Sep; ?(?):e2200767. doi: 10.1002/mnfr.202200767. [PMID: 37658490]
  • Hao-Long He, Guo-Shan Zhang, Shan-Feng Xiao, Hong-Hua Liu, Huan Zhong, Xiao-Rong Chang, Qiong Liu, Mi Liu. [Effects of moxibustion at "Tianshu"（ST25） and "Shangjuxu" （ST37） on colonic metabolites and inflammatory factors in rats with Crohn's disease]. Zhen ci yan jiu = Acupuncture research. 2023 Aug; 48(8):736-45. doi: 10.13702/j.1000?0607.20221276. [PMID: 37614131]
  • Alessandre C Crispim, Shirley M A Crispim, Jéssica R Rocha, Jeferson S Ursulino, Roberto R Sobrinho, Viviane A Porto, Edson S Bento, Antônio E G Santana, Luiz C Caetano. Light effects on Lasiodiplodia theobromae metabolome cultured in vitro. Metabolomics : Official journal of the Metabolomic Society. 2023 08; 19(8):75. doi: 10.1007/s11306-023-02041-7. [PMID: 37580624]
  • Vishal Varshney, Abhijit Hazra, Venkateswara Rao, Shraboni Ghosh, Nitin Uttam Kamble, Rakesh Kumar Achary, Shikha Gautam, Manoj Majee. The Arabidopsis F-box protein SKIP31 modulates seed maturation and seed vigor by targeting JAZ proteins independently of jasmonic acid-isoleucine. The Plant cell. 2023 Jul; ?(?):. doi: 10.1093/plcell/koad199. [PMID: 37462265]
  • Joel T Steyer, Richard B Todd. Branched-chain amino acid biosynthesis in fungi. Essays in biochemistry. 2023 Jul; ?(?):. doi: 10.1042/ebc20230003. [PMID: 37455545]
  • Noriyuki Konishi, Namiki Mitani-Ueno, Naoki Yamaji, Jian Feng Ma. Polar localization of a rice silicon transporter requires isoleucine at both C- and N-termini as well as positively charged residues. The Plant cell. 2023 05; 35(6):2232-2250. doi: 10.1093/plcell/koad073. [PMID: 36891818]
  • Marta Mendes Costa, Alda Pereira Da Silva, Carolina Santos, Joana Ferreira, Mário Rui Mascarenhas, Manuel Bicho, Ana Paula Barbosa. Influence of the TAS2R38 Gene Single Nucleotide Polymorphisms in Metabolism and Anthropometry in Thyroid Dysfunction. Nutrients. 2023 May; 15(9):. doi: 10.3390/nu15092214. [PMID: 37432370]
  • Andrei Z Damyanovich, Lisa Avery, James R Staples, K Wayne Marshall. 1H NMR Metabolic Profiling of Synovial Fluid from Patients with Anterior Cruciate Ligament Tears and Hemarthrosis. Osteoarthritis and cartilage. 2023 May; ?(?):. doi: 10.1016/j.joca.2023.03.016. [PMID: 37146959]
  • Lei Song, Yating Zhou, Yuxia Zhai, Xiangxiang Huo, Mengying Chen, Hong Shi, Yingli Yu, Yue Zhang, Kun Zhou. Sub-chronic toxicity of an aqueous extract of Epimedium sagittatum (Sieb. Et Zucc.) Maxim. in rats. Drug and chemical toxicology. 2023 May; 46(3):451-461. doi: 10.1080/01480545.2022.2050749. [PMID: 35287533]
  • Rina Saito, Toshiya Muto, Haruyuki Urano, Tsumugi Kitajima, Nobuki Kato, Eunsang Kwon, Minoru Ueda. (3R,7S)-12-Hydroxy- jasmonoyl-L-isoleucine is the genuine bioactive stereoisomer of a jasmonate metabolite in Arabidopsis thaliana. The Plant journal : for cell and molecular biology. 2023 Apr; ?(?):. doi: 10.1111/tpj.16256. [PMID: 37095639]
  • Kengo Hayashi, Nobuki Kato, Khurram Bashir, Haruna Nomoto, Misuzu Nakayama, Andrea Chini, Satoshi Takahashi, Hiroaki Saito, Raku Watanabe, Yousuke Takaoka, Maho Tanaka, Atsushi J Nagano, Motoaki Seki, Roberto Solano, Minoru Ueda. Subtype-selective agonists of plant hormone co-receptor COI1-JAZs identified from the stereoisomers of coronatine. Communications biology. 2023 03; 6(1):320. doi: 10.1038/s42003-023-04709-1. [PMID: 36966228]
  • Andrea Chini, Isabel Monte, Angel M Zamarreño, José M García-Mina, Roberto Solano. Evolution of the jasmonate ligands and their biosynthetic pathways. The New phytologist. 2023 Mar; ?(?):. doi: 10.1111/nph.18891. [PMID: 36942932]
  • Krishnan Raguvaran, Manickam Kalpana, Thulasiraman Manimegalai, Rajan Maheswaran. Bioefficacy of isolated compound l-isoleucine, N-allyloxycarbonyl-, and dodecyl ester from entomopathogenic actinobacteria Actinokineospora fastidiosa against agricultural insect pests, human vector mosquitoes, and antioxidant activities. Environmental science and pollution research international. 2023 Mar; 30(15):42608-42628. doi: 10.1007/s11356-022-23565-w. [PMID: 36260230]
  • Haiwen Chen, Jintao Cheng, Yuan Huang, Qiusheng Kong, Zhilong Bie. Comparative analysis of sugar, acid, and volatile compounds in CPPU-treated and honeybee-pollinated melon fruits during different developmental stages. Food chemistry. 2023 Feb; 401(?):134072. doi: 10.1016/j.foodchem.2022.134072. [PMID: 36108381]
  • Aslihan Cakmak, Emirhan Nemutlu, Samiye Yabanoglu-Ciftci, Ipek Baysal, Elif Kocaaga, Lutfi Coplu, Deniz Inal-Ince. Metabolomic, oxidative, and inflammatory responses to acute exercise in chronic obstructive pulmonary disease. Heart & lung : the journal of critical care. 2023 Jan; 59(?):52-60. doi: 10.1016/j.hrtlng.2023.01.011. [PMID: 36724589]
  • L H Kan, X Xu, Y M Chen, X M Wang, J L Li, F H Shen. [Correlation between intestinal and respiratory flora and their metabolites in a rat pneumoconiosis model]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. 2023 Jan; 41(1):21-30. doi: 10.3760/cma.j.cn121094-20211011-00495. [PMID: 36725290]
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