Rhamnetin (BioDeep_00000002499)

 

Secondary id: BioDeep_00000266234, BioDeep_00000396881

natural product human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


3 3 4 5-tetrahydroxy-7-methoxyflavone

化学式: C16H12O7 (316.0583)
中文名称: 鼠李素
谱图信息: 最多检出来源 Viridiplantae(plant) 13.25%

分子结构信息

SMILES: COc(c3)cc(O1)c(c(O)3)C(=O)C(O)=C1c(c2)cc(O)c(O)c2
InChI: InChI=1/C16H12O7/c1-22-8-5-11(19)13-12(6-8)23-16(15(21)14(13)20)7-2-3-9(17)10(18)4-7/h2-6,17-19,21H,1H3

描述信息

Acquisition and generation of the data is financially supported in part by CREST/JST.
Rhamnetin is a quercetin derivative found in Coriandrum sativum, inhibits secretory phospholipase A2, with antioxidant and anti-inflammatory activity[1].
Rhamnetin is a quercetin derivative found in Coriandrum sativum, inhibits secretory phospholipase A2, with antioxidant and anti-inflammatory activity[1].
Rhamnetin is a quercetin derivative found in Coriandrum sativum, inhibits secretory phospholipase A2, with antioxidant and anti-inflammatory activity[1].

同义名列表

7 个代谢物同义名

3 3 4 5-tetrahydroxy-7-methoxyflavone; 3,5,3,4-tetrahydroxy-7-methoxyflavone; 3,3,4,5-tetrahydroxy-7-methoxyflavone; 7-O-Methyl Quercetin; 7-methoxyquercetin; Rhamnetin; Rhamnetin



数据库引用编号

31 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(2)

代谢反应

15 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(13)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

260 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 14 AKT1, ANXA5, CASP3, CAT, EGFR, MAPK14, MAPK8, NQO1, PIK3CA, PPARG, PTGS2, SRC, TP53, TYR
Peripheral membrane protein 3 ANXA5, GORASP1, PTGS2
Endosome membrane 2 EGFR, NOTCH1
Endoplasmic reticulum membrane 3 EGFR, NOTCH1, PTGS2
Nucleus 10 AKT1, CASP3, EGFR, MAPK14, MAPK8, NOTCH1, NQO1, PPARG, SRC, TP53
cytosol 12 AKT1, ANXA5, CASP3, CAT, MAPK14, MAPK8, NOTCH1, NQO1, PIK3CA, PPARG, SRC, TP53
dendrite 1 NQO1
centrosome 1 TP53
nucleoplasm 8 AKT1, CASP3, MAPK14, MAPK8, NOTCH1, PPARG, SRC, TP53
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 5 AKT1, EGFR, NOTCH1, SRC, TNF
Lipid-anchor 1 SRC
Cytoplasmic side 1 GORASP1
lamellipodium 2 AKT1, PIK3CA
ruffle membrane 2 EGFR, SRC
Early endosome membrane 1 EGFR
Golgi apparatus membrane 1 GORASP1
Synapse 2 MAPK8, NQO1
cell cortex 1 AKT1
cell junction 2 EGFR, SRC
cell surface 3 EGFR, NOTCH1, TNF
glutamatergic synapse 6 AKT1, CASP3, EGFR, MAPK14, NOTCH1, SRC
Golgi apparatus 1 GORASP1
Golgi membrane 3 EGFR, GORASP1, NOTCH1
lysosomal membrane 1 GAA
mitochondrial inner membrane 1 SRC
neuronal cell body 4 CASP3, NQO1, SRC, TNF
postsynapse 1 AKT1
sarcolemma 1 ANXA5
Cytoplasm, cytosol 1 NQO1
Lysosome 3 GAA, SRC, TYR
acrosomal vesicle 1 NOTCH1
endosome 1 EGFR
plasma membrane 8 AKT1, EGFR, GAA, KNG1, NOTCH1, PIK3CA, SRC, TNF
Membrane 8 AKT1, ANXA5, CAT, EGFR, GAA, NOTCH1, NQO1, TP53
apical plasma membrane 2 EGFR, NOTCH1
axon 1 MAPK8
basolateral plasma membrane 1 EGFR
caveola 2 PTGS2, SRC
extracellular exosome 5 ANXA5, CAT, GAA, KNG1, SRC
Lysosome membrane 1 GAA
endoplasmic reticulum 3 NOTCH1, PTGS2, TP53
extracellular space 4 EGFR, IL6, KNG1, TNF
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 5 EGFR, PIK3CA, PPARG, SRC, TYR
Schaffer collateral - CA1 synapse 1 NOTCH1
adherens junction 1 NOTCH1
intercalated disc 1 PIK3CA
mitochondrion 4 CAT, MAPK14, SRC, TP53
protein-containing complex 5 AKT1, CAT, EGFR, PTGS2, TP53
intracellular membrane-bounded organelle 4 CAT, GAA, PPARG, TYR
Microsome membrane 1 PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 3 EGFR, NOTCH1, TYR
Secreted 2 GAA, IL6
extracellular region 8 ANXA5, CAT, GAA, IL6, KNG1, MAPK14, NOTCH1, TNF
Mitochondrion matrix 1 TP53
mitochondrial matrix 2 CAT, TP53
transcription regulator complex 1 TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
nuclear membrane 1 EGFR
external side of plasma membrane 2 ANXA5, TNF
microtubule cytoskeleton 1 AKT1
nucleolus 1 TP53
Melanosome membrane 1 TYR
cell-cell junction 1 AKT1
Golgi-associated vesicle 1 TYR
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Cytoplasm, perinuclear region 1 SRC
Mitochondrion inner membrane 1 SRC
Membrane raft 3 EGFR, SRC, TNF
Cell junction, focal adhesion 1 SRC
Cytoplasm, cytoskeleton 2 SRC, TP53
focal adhesion 4 ANXA5, CAT, EGFR, SRC
spindle 1 AKT1
cis-Golgi network 1 GORASP1
Peroxisome 1 CAT
intracellular vesicle 1 EGFR
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 1 TP53
PML body 1 TP53
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 2 ANXA5, KNG1
nuclear speck 1 MAPK14
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Late endosome 1 SRC
receptor complex 3 EGFR, NOTCH1, PPARG
Zymogen granule membrane 1 ANXA5
neuron projection 1 PTGS2
ciliary basal body 1 AKT1
chromatin 2 PPARG, TP53
Late endosome membrane 1 NOTCH1
phagocytic cup 1 TNF
podosome 1 SRC
Secreted, extracellular space 1 KNG1
spindle pole 1 MAPK14
actin filament 1 SRC
blood microparticle 1 KNG1
site of double-strand break 1 TP53
tertiary granule membrane 1 GAA
Melanosome 1 TYR
germ cell nucleus 1 TP53
replication fork 1 TP53
dendritic growth cone 1 SRC
basal plasma membrane 1 EGFR
synaptic membrane 2 EGFR, SRC
ficolin-1-rich granule lumen 2 CAT, MAPK14
secretory granule lumen 2 CAT, MAPK14
endoplasmic reticulum lumen 3 IL6, KNG1, PTGS2
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
platelet alpha granule lumen 1 KNG1
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
azurophil granule membrane 1 GAA
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GORASP1
postsynaptic density membrane 1 NOTCH1
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
vesicle membrane 1 ANXA5
clathrin-coated endocytic vesicle membrane 1 EGFR
[Isoform 1]: Nucleus 1 TP53
ficolin-1-rich granule membrane 1 GAA
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
postsynaptic specialization, intracellular component 1 SRC
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
endothelial microparticle 1 ANXA5
autolysosome lumen 1 GAA
dendritic filopodium 1 SRC
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[Notch 1 intracellular domain]: Nucleus 1 NOTCH1
MAML1-RBP-Jkappa- ICN1 complex 1 NOTCH1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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